Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| AKT3 | 10000 | v-akt murine thymoma viral oncogene homolog 3 | 1 | PKBG, RAC-gamma, PRKBG |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18813315 | 2008 | Cell line : - Source : The Melanoma Informatics, Tissue Resource and Pathology Core at The University of Texas MD Anderson Cancer Center. Sample Type : OCT-embedded frozen tumor No. of Sample : - Stage : - | Mass spectroscopy,transfection, western blotting. | Mutation | - | The AKT3 E17K mutation results in activation of AKT when expressed in human melanoma cells. |
| 26222778 | 2015 | Cell line : - Source : Databases Sample Type : - No. of Sample : - Stage : - | Microarray | Up-regulation | - | Kras, araf, pik3r5, ralgds and akt3 via our novel
designed parameters illustrating high statistical significance. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Pleckstrin homology (PH) domain containing |
| Description | The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
| Chromosome | 1 |
| Location | 1q44 |
| Start | 243651535 |
| End | 244014381 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 362847 |
| OMIM ID | 611223 |
| HGNC ID | HGNC:393 |
| Unigene ID | Hs.498292 |
| Ensembl ID | ENSG00000117020 |
| PharmGKB ID | PA24686 |
Protein Information
| Protein ID | NP_001193658.1 |
|---|---|
| Protein Name | v-akt murine thymoma viral oncogene homolog 3 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 479 |
| Uniprot ID | Q9UPY5 |
| Ensembl Protein ID | ENSP00000280612 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 472 |
| T | Phosphorylation | 305 |
| T | Phosphorylation | 305 |
| S | Phosphorylation | 120 |
| S | Phosphorylation | 120 |
| T | Phosphorylation | 305 |
| T | Phosphorylation | 305 |
| S | Phosphorylation | 472 |
| S | Phosphorylation | 123;- |
| S | Phosphorylation | 123;- |
| S | Acetylation | 2 |
| S | Acetylation | 2 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 8115 | TCL1A | 1744 | NP_068801.1 | in vitro;in vivo | 11707444 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Acute myeloid leukemia | hsa05221 |
| Adipocytokine signaling pathway | hsa04920 |
| Adrenergic signaling in cardiomyocytes | hsa04261 |
| AGE-RAGE signaling pathway in diabetic complications | hsa04933 |
| AMPK signaling pathway | hsa04152 |
| Apoptosis | hsa04210 |
| B cell receptor signaling pathway | hsa04662 |
| cAMP signaling pathway | hsa04024 |
| Carbohydrate digestion and absorption | hsa04973 |
| Central carbon metabolism in cancer | hsa05230 |
| cGMP-PKG signaling pathway | hsa04022 |
| Chagas disease (American trypanosomiasis) | hsa05142 |
| Chemokine signaling pathway | hsa04062 |
| Choline metabolism in cancer | hsa05231 |
| Cholinergic synapse | hsa04725 |
| Chronic myeloid leukemia | hsa05220 |
| Colorectal cancer | hsa05210 |
| Dopaminergic synapse | hsa04728 |
| Endometrial cancer | hsa05213 |
| Epstein-Barr virus infection | hsa05169 |
| ErbB signaling pathway | hsa04012 |
| Estrogen signaling pathway | hsa04915 |
| Fc epsilon RI signaling pathway | hsa04664 |
| Fc gamma R-mediated phagocytosis | hsa04666 |
| Focal adhesion | hsa04510 |
| FoxO signaling pathway | hsa04068 |
| Glioma | hsa05214 |
| Glucagon signaling pathway | hsa04922 |
| Hepatitis B | hsa05161 |
| Hepatitis C | hsa05160 |
| HIF-1 signaling pathway | hsa04066 |
| HTLV-I infection | hsa05166 |
| Influenza A | hsa05164 |
| Insulin resistance | hsa04931 |
| Insulin signaling pathway | hsa04910 |
| Jak-STAT signaling pathway | hsa04630 |
| Longevity regulating pathway - mammal | hsa04211 |
| Longevity regulating pathway - multiple species | hsa04213 |
| MAPK signaling pathway | hsa04010 |
| Measles | hsa05162 |
| Melanoma | hsa05218 |
| mTOR signaling pathway | hsa04150 |
| Neurotrophin signaling pathway | hsa04722 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 |
| Non-small cell lung cancer | hsa05223 |
| Osteoclast differentiation | hsa04380 |
| Pancreatic cancer | hsa05212 |
| Pathways in cancer | hsa05200 |
| Phospholipase D signaling pathway | hsa04072 |
| PI3K-Akt signaling pathway | hsa04151 |
| Platelet activation | hsa04611 |
| Progesterone-mediated oocyte maturation | hsa04914 |
| Prolactin signaling pathway | hsa04917 |
| Prostate cancer | hsa05215 |
| Proteoglycans in cancer | hsa05205 |
| Rap1 signaling pathway | hsa04015 |
| Ras signaling pathway | hsa04014 |
| Regulation of lipolysis in adipocytes | hsa04923 |
| Renal cell carcinoma | hsa05211 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| Small cell lung cancer | hsa05222 |
| Sphingolipid signaling pathway | hsa04071 |
| T cell receptor signaling pathway | hsa04660 |
| Thyroid hormone signaling pathway | hsa04919 |
| Tight junction | hsa04530 |
| TNF signaling pathway | hsa04668 |
| Toll-like receptor signaling pathway | hsa04620 |
| Toxoplasmosis | hsa05145 |
| Tuberculosis | hsa05152 |
| VEGF signaling pathway | hsa04370 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05593 | 132-479 | STKc_PKB_gamma |
| cl21453 | 132-479 | PKc_like superfamily |
| cd01241 | 4-110 | PH_PKB |
| cl17171 | 4-110 | PH-like superfamily |
| cd05571 | 152-476 | STKc_PKB |
| cd05595 | 152-476 | STKc_PKB_beta |
| cd05594 | 126-477 | STKc_PKB_alpha |
| cd05570 | 152-473 | STKc_PKC |
| cd05575 | 152-473 | STKc_SGK |
| cd05123 | 154-405 | STKc_AGC |
| cd05589 | 148-475 | STKc_PKN |
| cd05592 | 152-473 | STKc_nPKC_theta_like |
| cd05584 | 151-450 | STKc_p70S6K |
| cd05580 | 146-436 | STKc_PKA_like |
| cd05587 | 151-473 | STKc_cPKC |
| cd05603 | 152-448 | STKc_SGK2 |
| cd05604 | 151-444 | STKc_SGK3 |
| cd05591 | 152-473 | STKc_nPKC_epsilon |
| cd05590 | 152-475 | STKc_nPKC_eta |
| cd05602 | 146-474 | STKc_SGK1 |
| cd05616 | 147-473 | STKc_cPKC_beta |
| cd05586 | 154-440 | STKc_Sck1_like |
| cd05582 | 152-448 | STKc_RSK_N |
| cd05585 | 153-442 | STKc_YPK1_like |
| cd05588 | 152-448 | STKc_aPKC |
| cd14209 | 147-437 | STKc_PKA |
| cd05615 | 145-471 | STKc_cPKC_alpha |
| cd05619 | 144-458 | STKc_nPKC_theta |
| cd05614 | 147-449 | STKc_MSK2_N |
| cd05620 | 152-458 | STKc_nPKC_delta |
| cd05612 | 147-436 | STKc_PRKX_like |
| cd05583 | 154-408 | STKc_MSK_N |
| cd05617 | 145-473 | STKc_aPKC_zeta |
| cd05574 | 147-426 | STKc_phototropin_like |
| cd05613 | 147-424 | STKc_MSK1_N |
| cd05573 | 146-474 | STKc_ROCK_NDR_like |
| cd05618 | 145-473 | STKc_aPKC_iota |
| cd05579 | 156-410 | STKc_MAST_like |
| cd05599 | 146-473 | STKc_NDR_like |
| cd14003 | 151-402 | STKc_AMPK-like |
| cd05117 | 147-404 | STKc_CAMK |
| cd14007 | 147-404 | STKc_Aurora |
| cd05572 | 154-412 | STKc_cGK |
| cd05581 | 146-405 | STKc_PDK1 |
| cd05578 | 148-405 | STKc_Yank1 |
| cd05601 | 146-437 | STKc_CRIK |
| cd05577 | 154-424 | STKc_GRK |
| cd05598 | 146-473 | STKc_LATS |
| cd05609 | 147-410 | STKc_MAST |
| cd05600 | 141-437 | STKc_Sid2p_like |
| cd05597 | 147-449 | STKc_DMPK_like |
| cd05605 | 148-424 | STKc_GRK4_like |
| cd05596 | 142-453 | STKc_ROCK |
| cd05611 | 151-410 | STKc_Rim15_like |
| cd08215 | 147-405 | STKc_Nek |
| cd05629 | 146-449 | STKc_NDR_like_fungal |
| cd05608 | 148-424 | STKc_GRK1 |
| cd05606 | 153-424 | STKc_beta_ARK |
| cd05630 | 148-424 | STKc_GRK6 |
| cd14663 | 147-404 | STKc_SnRK3 |
| cd05610 | 144-442 | STKc_MASTL |
| cd05631 | 148-424 | STKc_GRK4 |
| cd05624 | 146-449 | STKc_MRCK_beta |
| cd05633 | 144-440 | STKc_GRK3 |
| cd05632 | 146-424 | STKc_GRK5 |
| cd14083 | 148-388 | STKc_CaMKI |
| cd06606 | 152-405 | STKc_MAPKKK |
| cd00180 | 154-403 | PKc |
| cd05623 | 118-449 | STKc_MRCK_alpha |
| cd14008 | 154-405 | STKc_LKB1_CaMKK |
| cd14002 | 146-390 | STKc_STK36 |
| cd14073 | 148-388 | STKc_NUAK |
| cd14095 | 148-402 | STKc_DCKL |
| cd14081 | 152-405 | STKc_BRSK1_2 |
| cd05607 | 148-424 | STKc_GRK7 |
| cd05622 | 125-437 | STKc_ROCK1 |
| cd14079 | 152-405 | STKc_AMPK_alpha |
| cd05621 | 147-437 | STKc_ROCK2 |
| cd14223 | 147-440 | STKc_GRK2 |
| cd14166 | 142-407 | STKc_CaMKI_gamma |
| cd14099 | 152-405 | STKc_PLK |
| cd05122 | 147-405 | PKc_STE |
| cd14014 | 151-401 | STKc_PknB_like |
| cd14084 | 152-403 | STKc_Chk2 |
| cd14078 | 154-389 | STKc_MELK |
| cd14167 | 148-407 | STKc_CaMKI_alpha |
| cd14161 | 148-388 | STKc_NUAK2 |
| cd05627 | 145-437 | STKc_NDR2 |
| cd06623 | 146-404 | PKc_MAPKK_plant_like |
| cd14072 | 148-388 | STKc_MARK |
| cd14077 | 147-404 | STKc_Kin1_2 |
| cd05628 | 147-437 | STKc_NDR1 |
| cd14080 | 151-405 | STKc_TSSK-like |
| cd14097 | 154-402 | STKc_STK33 |
| cd14098 | 147-402 | STKc_Rad53_Cds1 |
| cd14093 | 153-405 | STKc_PhKG |
| cd14116 | 144-402 | STKc_Aurora-A |
| cd05626 | 148-467 | STKc_LATS2 |
| cd14169 | 154-407 | STKc_CaMKI_beta |
| cd14071 | 148-390 | STKc_SIK |
| cd14096 | 146-402 | STKc_RCK1-like |
| cd14117 | 141-421 | STKc_Aurora-B_like |
| cd05625 | 148-436 | STKc_LATS1 |
| cd14168 | 148-407 | STKc_CaMKI_delta |
| cd14076 | 154-404 | STKc_Kin4 |
| cd14006 | 154-389 | STKc_MLCK-like |
| cd14009 | 154-390 | STKc_ATG1_ULK_like |
| cd08530 | 147-390 | STKc_CNK2-like |
| cd14162 | 152-405 | STKc_TSSK4-like |
| cd14087 | 148-402 | STKc_PSKH1 |
| cd08529 | 147-401 | STKc_FA2-like |
| cd14075 | 154-404 | STKc_NIM1 |
| cd13999 | 154-388 | STKc_MAP3K-like |
| cd14185 | 152-404 | STKc_DCKL3 |
| cd06614 | 148-406 | STKc_PAK |
| cd14103 | 154-402 | STKc_MLCK |
| cd14085 | 148-409 | STKc_CaMKIV |
| cd14086 | 154-404 | STKc_CaMKII |
| cd14010 | 154-404 | STKc_ULK4 |
| cd14091 | 147-430 | STKc_RSK_C |
| cd14662 | 148-404 | STKc_SnRK2 |
| cd14118 | 154-389 | STKc_CAMKK |
| cd14074 | 148-388 | STKc_SNRK |
| cd14189 | 152-405 | STKc_PLK3 |
| cd14105 | 148-404 | STKc_DAPK |
| cd05118 | 151-405 | STKc_CMGC |
| cd13994 | 154-405 | STKc_HAL4_like |
| cd06632 | 152-404 | STKc_MEKK1_plant |
| cd06625 | 152-405 | STKc_MEKK3_like |
| cd14188 | 152-405 | STKc_PLK2 |
| cd08217 | 147-405 | STKc_Nek2 |
| cd14089 | 152-402 | STKc_MAPKAPK |
| cd14665 | 148-389 | STKc_SnRK2-3 |
| cd14092 | 152-389 | STKc_MSK_C |
| cd08222 | 154-404 | STKc_Nek11 |
| cd06627 | 152-405 | STKc_Cdc7_like |
| cd14004 | 147-388 | STKc_PASK |
| cd08218 | 151-388 | STKc_Nek1 |
| cd14184 | 152-402 | STKc_DCKL2 |
| cd14179 | 152-389 | STKc_MSK1_C |
| cd06605 | 146-405 | PKc_MAPKK |
| cd14181 | 148-405 | STKc_PhKG2 |
| cd14106 | 152-405 | STKc_DRAK |
| cd14165 | 154-405 | STKc_TSSK1_2-like |
| cd14070 | 152-388 | STKc_HUNK |
| cd06609 | 146-404 | STKc_MST3_like |
| cd14186 | 147-389 | STKc_PLK4 |
| cd06626 | 152-404 | STKc_MEKK4 |
| cd14194 | 154-389 | STKc_DAPK1 |
| cd14119 | 154-405 | STKc_LKB1 |
| cd14182 | 148-405 | STKc_PhKG1 |
| cd14196 | 148-404 | STKc_DAPK2 |
| cd06611 | 154-417 | STKc_SLK_like |
| cd14090 | 153-402 | STKc_Mnk |
| cd14088 | 148-404 | STKc_CaMK_like |
| cd06612 | 146-405 | STKc_MST1_2 |
| cd14183 | 152-388 | STKc_DCKL1 |
| cd07829 | 150-405 | STKc_CDK_like |
| cd14121 | 154-389 | STKc_ULK3 |
| cd14082 | 152-381 | STKc_PKD |
| cd08225 | 148-388 | STKc_Nek5 |
| cd14069 | 146-405 | STKc_Chk1 |
| cd14199 | 145-389 | STKc_CaMKK2 |
| cd06648 | 147-405 | STKc_PAK_II |
| cd06613 | 147-405 | STKc_MAP4K3_like |
| cd08219 | 147-388 | STKc_Nek3 |
| cd14187 | 143-388 | STKc_PLK1 |
| cd14200 | 154-390 | STKc_CaMKK1 |
| cd14120 | 154-404 | STKc_ULK1_2-like |
| cd06647 | 154-405 | STKc_PAK_I |
| cd08223 | 147-404 | STKc_Nek4 |
| cd14180 | 154-389 | STKc_MSK2_C |
| cd07833 | 146-405 | STKc_CDKL |
| cd14005 | 152-405 | STKc_PIM |
| cd06656 | 154-405 | STKc_PAK3 |
| cd14198 | 145-388 | STKc_DRAK2 |
| cd08528 | 147-394 | STKc_Nek10 |
| cd14195 | 154-389 | STKc_DAPK3 |
| cd06610 | 146-405 | STKc_OSR1_SPAK |
| cd06654 | 154-405 | STKc_PAK1 |
| cd14190 | 152-392 | STKc_MLCK2 |
| cd14202 | 147-405 | STKc_ULK1 |
| cd14171 | 147-389 | STKc_MAPKAPK5 |
| cd14172 | 152-389 | STKc_MAPKAPK3 |
| cd14113 | 154-388 | STKc_Trio_C |
| cd08220 | 147-402 | STKc_Nek8 |
| cd14191 | 148-389 | STKc_MLCK1 |
| cd14094 | 151-402 | STKc_CASK |
| cd14192 | 152-405 | STKc_MLCK3 |
| cd06659 | 149-405 | STKc_PAK6 |
| cd06655 | 154-405 | STKc_PAK2 |
| cd14111 | 155-350 | STKc_SPEG_rpt2 |
| cd14174 | 152-404 | STKc_Mnk1 |
| cd14175 | 154-413 | STKc_RSK1_C |
| cd14193 | 152-402 | STKc_MLCK4 |
| cd07830 | 151-405 | STKc_MAK_like |
| cd06644 | 140-409 | STKc_STK10 |
| cd14114 | 148-389 | STKc_Twitchin_like |
| cd13990 | 151-388 | STKc_TLK |
| cd14176 | 154-402 | STKc_RSK2_C |
| cd06629 | 152-404 | STKc_Bck1_like |
| cd00192 | 152-358 | PTKc |
| cd14178 | 154-404 | STKc_RSK3_C |
| cd13993 | 154-388 | STKc_Pat1_like |
| cd13974 | 164-389 | STKc_SHIK |
| cd07834 | 148-440 | STKc_MAPK |
| cd14197 | 154-402 | STKc_DRAK1 |
| cd06658 | 154-405 | STKc_PAK5 |
| cd13987 | 154-403 | STKc_SBK1 |
| cd07841 | 148-406 | STKc_CDK7 |
| cd07838 | 148-405 | STKc_CDK4_6_like |
| cd14170 | 152-389 | STKc_MAPKAPK2 |
| cd06628 | 153-404 | STKc_Byr2_like |
| cd06643 | 145-409 | STKc_SLK |
| cd06917 | 148-404 | STKc_NAK1_like |
| cd06640 | 148-423 | STKc_MST4 |
| cd06608 | 146-404 | STKc_myosinIII_N_like |
| cd06657 | 148-406 | STKc_PAK4 |
| cd07832 | 154-405 | STKc_CCRK |
| cd14173 | 152-402 | STKc_Mnk2 |
| cd14201 | 143-405 | STKc_ULK2 |
| cd13996 | 146-388 | STKc_EIF2AK |
| cd06624 | 154-404 | STKc_ASK |
| cd14059 | 154-350 | STKc_MAP3K12_13 |
| cd13997 | 147-388 | PKc_Wee1_like |
| cd14107 | 148-405 | STKc_obscurin_rpt1 |
| cd14177 | 154-406 | STKc_RSK4_C |
| cd06652 | 152-404 | STKc_MEKK2 |
| cd14046 | 146-388 | STKc_EIF2AK4_GCN2_rpt2 |
| cd07835 | 150-405 | STKc_CDK1_CdkB_like |
| cd07840 | 148-405 | STKc_CDK9_like |
| cd13989 | 154-346 | STKc_IKK |
| cd14137 | 151-405 | STKc_GSK3 |
| cd06620 | 147-388 | PKc_Byr1_like |
| cd08224 | 147-388 | STKc_Nek6_7 |
| cd06641 | 148-423 | STKc_MST3 |
| cd06642 | 148-404 | STKc_STK25 |
| cd06653 | 152-404 | STKc_MEKK3_like_u1 |
| cd06651 | 152-404 | STKc_MEKK3 |
| cd07831 | 152-405 | STKc_MOK |
| cd06630 | 152-405 | STKc_MEKK1 |
| cd06645 | 141-406 | STKc_MAP4K3 |
| cd14115 | 154-388 | STKc_Kalirin_C |
| cd14164 | 148-388 | STKc_TSSK6-like |
| cd06646 | 141-404 | STKc_MAP4K5 |
| cd07851 | 151-406 | STKc_p38 |
| cd05576 | 157-405 | STKc_RPK118_like |
| cd06631 | 153-404 | STKc_YSK4 |
| cd14110 | 144-388 | STKc_obscurin_rpt2 |
| cd14061 | 153-346 | STKc_MLK |
| cd14133 | 151-405 | PKc_DYRK_like |
| cd14163 | 152-384 | STKc_TSSK3-like |
| cd08221 | 151-388 | STKc_Nek9 |
| cd07845 | 143-405 | STKc_CDK10 |
| cd07860 | 148-405 | STKc_CDK2_3 |
| cd07866 | 144-405 | STKc_BUR1 |
| cd14039 | 154-398 | STKc_IKK_alpha |
| cd14066 | 154-348 | STKc_IRAK |
| cd14050 | 148-388 | PKc_Myt1 |
| cd06621 | 146-388 | PKc_Pek1_like |
| cd08228 | 145-388 | STKc_Nek6 |
| cd14038 | 154-383 | STKc_IKK_beta |
| cd07871 | 150-405 | STKc_PCTAIRE3 |
| cd13978 | 154-351 | STKc_RIP |
| cd14104 | 148-402 | STKc_Titin |
| cd06615 | 147-400 | PKc_MEK |
| cd07847 | 150-405 | STKc_CDKL1_4 |
| cd07846 | 146-405 | STKc_CDKL2_3 |
| cd07877 | 148-443 | STKc_p38alpha |
| cd14210 | 151-405 | PKc_DYRK |
| cd14012 | 200-404 | PK_eIF2AK_GCN2_rpt1 |
| cd07880 | 151-422 | STKc_p38gamma |
| cd14131 | 151-404 | PKc_Mps1 |
| cd07855 | 154-407 | STKc_ERK5 |
| cd14041 | 144-389 | STKc_TLK2 |
| cd06638 | 148-404 | STKc_myosinIIIA_N |
| cd05081 | 150-339 | PTKc_Jak3_rpt2 |
| cd06636 | 148-404 | STKc_MAP4K4_6_N |
| cd14052 | 147-338 | PTKc_Wee1_fungi |
| cd07848 | 146-352 | STKc_CDKL5 |
| cd08229 | 144-388 | STKc_Nek7 |
| cd06637 | 148-404 | STKc_TNIK |
| cd14040 | 144-377 | STKc_TLK1 |
| cd14058 | 154-388 | STKc_TAK1 |
| cd14019 | 146-405 | STKc_Cdc7 |
| cd07873 | 150-405 | STKc_PCTAIRE1 |
| cd14147 | 147-388 | STKc_MLK3 |
| cd07844 | 150-405 | STKc_PCTAIRE_like |
| cd07861 | 149-405 | STKc_CDK1_euk |
| cd14222 | 154-340 | STKc_LIMK2 |
| cd14022 | 245-405 | PK_TRB2 |
| cd13983 | 150-405 | STKc_WNK |
| cd14062 | 154-348 | STKc_Raf |
| cd13986 | 148-388 | STKc_16 |
| cd14047 | 147-402 | STKc_EIF2AK2_PKR |
| cd06650 | 146-354 | PKc_MEK1 |
| cd14150 | 151-348 | STKc_A-Raf |
| cd14145 | 147-366 | STKc_MLK1 |
| cd14065 | 154-345 | PKc_LIMK_like |
| cd05039 | 145-346 | PTKc_Csk_like |
| cd07852 | 258-406 | STKc_MAPK15-like |
| cd13976 | 238-405 | PK_TRB |
| cd05074 | 152-388 | PTKc_Tyro3 |
| cd06619 | 147-363 | PKc_MKK5 |
| cd07836 | 148-405 | STKc_Pho85 |
| cd07865 | 146-405 | STKc_CDK9 |
| cd06622 | 146-413 | PKc_PBS2_like |
| cd13985 | 151-388 | STKc_GAK_like |
| cd05038 | 150-339 | PTKc_Jak_rpt2 |
| cd13979 | 154-352 | STKc_Mos |
| cd14148 | 153-350 | STKc_MLK2 |
| cd14101 | 153-388 | STKc_PIM2 |
| cd14154 | 154-344 | STKc_LIMK |
| cd14146 | 153-350 | STKc_MLK4 |
| cd14102 | 153-388 | STKc_PIM3 |
| cd14023 | 238-405 | PK_TRB1 |
| cd06639 | 146-388 | STKc_myosinIIIB_N |
| cd06649 | 146-354 | PKc_MEK2 |
| cd05082 | 145-346 | PTKc_Csk |
| cd06633 | 151-404 | STKc_TAO3 |
| cd13988 | 154-346 | STKc_TBK1 |
| cd07872 | 150-405 | STKc_PCTAIRE2 |
| cd14048 | 145-366 | STKc_EIF2AK3_PERK |
| cd14024 | 229-402 | PK_TRB3 |
| cd07879 | 151-430 | STKc_p38delta |
| cd14134 | 151-405 | PKc_CLK |
| cd06607 | 148-404 | STKc_TAO |
| cd14100 | 153-388 | STKc_PIM1 |
| cd14151 | 154-358 | STKc_B-Raf |
| cd14049 | 145-340 | STKc_EIF2AK1_HRI |
| cd14000 | 153-354 | STKc_LRRK |
| cd14108 | 148-405 | STKc_SPEG_rpt1 |
| cd05059 | 147-360 | PTKc_Tec_like |
| cd14109 | 152-405 | PK_Unc-89_rpt1 |
| cd14221 | 154-344 | STKc_LIMK1 |
| cd07870 | 151-346 | STKc_PFTAIRE2 |
| cd07856 | 143-389 | STKc_Sty1_Hog1 |
| cd07858 | 152-389 | STKc_TEY_MAPK |
| cd14063 | 147-352 | PK_KSR |
| cd07878 | 151-444 | STKc_p38beta |
| cd07869 | 146-346 | STKc_PFTAIRE1 |
| cd06635 | 148-404 | STKc_TAO1 |
| cd07849 | 147-406 | STKc_ERK1_2_like |
| cd06618 | 144-404 | PKc_MKK7 |
| cd07843 | 147-405 | STKc_CDC2L1 |
| cd05080 | 140-340 | PTKc_Tyk2_rpt2 |
| cd07853 | 154-407 | STKc_NLK |
| cd14031 | 185-406 | STKc_WNK3 |
| cd07863 | 154-405 | STKc_CDK4 |
| cd14205 | 150-339 | PTKc_Jak2_rpt2 |
| cd14149 | 154-346 | STKc_C-Raf |
| cd05079 | 154-340 | PTKc_Jak1_rpt2 |
| cd06634 | 148-350 | STKc_TAO2 |
| cd06616 | 144-414 | PKc_MKK4 |
| cd14033 | 196-405 | STKc_WNK4 |
| cd14064 | 154-346 | PKc_TNNI3K |
| cd05113 | 147-346 | PTKc_Btk_Bmx |
| cd05045 | 152-388 | PTKc_RET |
| cd05084 | 154-358 | PTKc_Fes |
| cd14037 | 152-388 | STKc_NAK_like |
| cd13982 | 254-405 | STKc_IRE1 |
| cd07857 | 148-415 | STKc_MPK1 |
| cd05085 | 152-338 | PTKc_Fer |
| cd07842 | 148-405 | STKc_CDK8_like |
| cd05083 | 152-346 | PTKc_Chk |
| cd14032 | 196-406 | STKc_WNK2_like |
| cd14060 | 155-346 | STKc_MLTK |
| cd13975 | 254-351 | PKc_Dusty |
| cd14026 | 151-346 | STKc_RIP2 |
| cd14068 | 153-393 | STKc_LRRK2 |
| cd14224 | 148-342 | PKc_DYRK2_3 |
| cd07854 | 151-406 | STKc_MAPK4_6 |
| cd14226 | 145-360 | PKc_DYRK1 |
| cd07850 | 246-389 | STKc_JNK |
| cd06617 | 147-406 | PKc_MKK3_6 |
| cd07876 | 246-421 | STKc_JNK2 |
| cd14056 | 152-341 | STKc_TGFbR_I |
| cd14156 | 154-345 | PKc_LIMK_like_unk |
| cd07839 | 148-405 | STKc_CDK5 |
| smart00133 | 406-475 | S_TK_X |
| cl11395 | 406-475 | Pkinase_C superfamily |
| cd14025 | 152-346 | STKc_RIP4_like |
| cd07864 | 142-404 | STKc_CDK12 |
| cd07862 | 154-393 | STKc_CDK6 |
| cd14132 | 144-405 | STKc_CK2_alpha |
| cd05032 | 145-359 | PTKc_InsR_like |
| cd14158 | 153-358 | STKc_IRAK4 |
| cd05060 | 154-346 | PTKc_Syk_like |
| cd05041 | 154-358 | PTKc_Fes_like |
| cd14030 | 185-405 | STKc_WNK1 |
| cd05112 | 154-358 | PTKc_Itk |
| cd14212 | 151-352 | PKc_YAK1 |
| cd14016 | 151-364 | STKc_CK1 |
| cd05148 | 147-370 | PTKc_Srm_Brk |
| cd05114 | 150-358 | PTKc_Tec_Rlk |
| cd05057 | 145-346 | PTKc_EGFR_like |
| cd13995 | 156-402 | STKc_MAP3K8 |
| cd07875 | 246-424 | STKc_JNK1 |
| cd14664 | 154-346 | STK_BAK1_like |
| cd14155 | 154-345 | PKc_TESK |
| cd05095 | 154-356 | PTKc_DDR2 |
| cd13998 | 153-339 | STKc_TGFbR-like |
| cd13991 | 154-348 | STKc_NIK |
| cd14027 | 154-352 | STKc_RIP1 |
| cd13977 | 221-389 | STKc_PDIK1L |
| cd14229 | 148-347 | STKc_HIPK3 |
| cd07859 | 151-385 | STKc_TDY_MAPK |
| cd14227 | 146-347 | STKc_HIPK2 |
| cd05035 | 152-359 | PTKc_TAM |
| smart00233 | 6-107 | PH |
| cd14228 | 146-347 | STKc_HIPK1 |
| cd14211 | 148-347 | STKc_HIPK |
| pfam00169 | 6-105 | PH |
| cd14214 | 154-390 | PKc_CLK3 |
| cd07837 | 148-405 | STKc_CdkB_plant |
| cd05043 | 153-354 | PTK_Ryk |
| cd05056 | 152-346 | PTKc_FAK |
| cd13968 | 154-291 | PKc_like |
| cd08216 | 151-405 | PK_STRAD |
| cd05097 | 154-356 | PTKc_DDR_like |
| cd07874 | 243-421 | STKc_JNK3 |
| cd14036 | 152-389 | STKc_GAK |
| cd05116 | 154-338 | PTKc_Syk |
| cd05075 | 152-358 | PTKc_Axl |
| cd05072 | 151-346 | PTKc_Lyn |
| cd05101 | 152-358 | PTKc_FGFR2 |
| cd05047 | 153-356 | PTKc_Tie |
| cd14159 | 154-345 | STKc_IRAK1 |
| cd05046 | 151-366 | PTK_CCK4 |
| cd14204 | 152-388 | PTKc_Mer |
| cd05099 | 152-358 | PTKc_FGFR4 |
| cd05048 | 144-358 | PTKc_Ror |
| cd14112 | 148-388 | STKc_Unc-89_rpt2 |
| cd14055 | 152-340 | STKc_TGFbR2_like |
| cd05058 | 152-347 | PTKc_Met_Ron |
| cd05067 | 149-346 | PTKc_Lck_Blk |
| cd14011 | 158-405 | PK_SCY1_like |
| cd14152 | 152-354 | STKc_KSR1 |
| cd14067 | 154-345 | STKc_LRRK1 |
| cd05098 | 152-358 | PTKc_FGFR1 |
| cd05050 | 146-354 | PTKc_Musk |
| cd05092 | 154-389 | PTKc_TrkA |
| cd05053 | 151-358 | PTKc_FGFR |
| cd14136 | 154-405 | STKc_SRPK |
| cd05066 | 152-350 | PTKc_EphR_A |
| cd14142 | 151-339 | STKc_ACVR1_ALK1 |
| cd14225 | 148-352 | PKc_DYRK4 |
| cd05100 | 152-358 | PTKc_FGFR3 |
| cd14153 | 152-354 | PK_KSR2 |
| cd14206 | 150-361 | PTKc_Aatyk3 |
| cd05040 | 152-339 | PTKc_Ack_like |
| cd05090 | 196-358 | PTKc_Ror1 |
| cd05034 | 152-346 | PTKc_Src_like |
| cd05068 | 151-346 | PTKc_Frk_like |
| cd05052 | 132-339 | PTKc_Abl |
| cd05065 | 152-388 | PTKc_EphR_B |
| cd13992 | 192-388 | PK_GC |
| cd05033 | 152-388 | PTKc_EphR |
| cd05088 | 146-356 | PTKc_Tie2 |
| cd05093 | 154-389 | PTKc_TrkB |
| cd05087 | 150-367 | PTKc_Aatyk1 |
| cd05042 | 154-367 | PTKc_Aatyk |
| cd13276 | 8-102 | PH_AtPH1 |
| cd05063 | 152-358 | PTKc_EphR_A2 |
| cd14213 | 154-366 | PKc_CLK1_4 |
| cd05089 | 147-356 | PTKc_Tie1 |
| cd05096 | 154-356 | PTKc_DDR1 |
| cd14018 | 239-405 | STKc_PINK1 |
| cd05073 | 152-346 | PTKc_Hck |
| cd05108 | 147-346 | PTKc_EGFR |
| cd05070 | 151-358 | PTKc_Fyn |
| cd05115 | 154-346 | PTKc_Zap-70 |
| cd05061 | 151-359 | PTKc_InsR |
| cd14203 | 152-356 | PTKc_Src_Fyn_like |
| cd05044 | 152-346 | PTKc_c-ros |
| cd14143 | 220-348 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd14215 | 148-366 | PKc_CLK2 |
| cd13282 | 8-110 | PH1_PLEKHH1_PLEKHH2 |
| cd14001 | 196-340 | PKc_TOPK |
| cd00821 | 8-102 | PH |
| cd13263 | 6-106 | PH_RhoGap25-like |
| cd13215 | 5-105 | PH-GRAM1_AGT26 |
| cd13389 | 6-112 | PH1_FGD5_FGD6 |
| cd13328 | 8-102 | PH1_FDG_family |
| smart00220 | 148-405 | S_TKc |
| PTZ00263 | 133-436 | PTZ00263 |
| pfam00069 | 148-405 | Pkinase |
| PTZ00426 | 135-436 | PTZ00426 |
| COG0515 | 147-476 | SPS1 |
| PHA03390 | 157-406 | pk1 |
| pfam07714 | 151-358 | Pkinase_Tyr |
| smart00221 | 151-358 | STYKc |
| PTZ00267 | 171-388 | PTZ00267 |
| smart00219 | 151-358 | TyrKc |
| PLN00034 | 121-407 | PLN00034 |
| PTZ00283 | 152-388 | PTZ00283 |
| PTZ00024 | 152-405 | PTZ00024 |
| PHA03212 | 180-377 | PHA03212 |
| PHA03209 | 148-340 | PHA03209 |
| PTZ00266 | 145-384 | PTZ00266 |
| PLN00009 | 145-405 | PLN00009 |
| PRK13184 | 145-388 | pknD |
| PTZ00036 | 113-389 | PTZ00036 |
| PHA03207 | 195-347 | PHA03207 |
| PTZ00284 | 131-361 | PTZ00284 |
| PHA03210 | 247-340 | PHA03210 |
| TIGR03903 | 175-343 | TOMM_kin_cyc |
| PHA03211 | 183-338 | PHA03211 |
Ontology Information
| HPRD ID | 6448 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | GTPase activator activity (GO:0005096) |
| Biological Process | Cell migration (GO:0016477) |
Drug Information
No matching records could be found.