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General Information
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24811787 | 2014 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 12 Stage : - | Illumina Infinium Human Methylation 450 BeadChip | Methylation | - | Aberrant methylation of the DCLRE1C and GPC6 genes are presented here for the first time and are therefore of special interest for further validation as novel candidate biomarker genes in CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Proteoglycans / Cell Surface : Glypicans |
| Description | The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. [provided by RefSeq, Jan 2009] |
| Chromosome | 13 |
| Location | 13q32 |
| Start | 93879078 |
| End | 95060274 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 1181197 |
| OMIM ID | 604404 |
| HGNC ID | HGNC:4454 |
| Unigene ID | Hs.444329 |
| Ensembl ID | ENSG00000183098 |
| PharmGKB ID | PA28835 |
Protein Information
| Protein ID | NP_005699.1 |
|---|---|
| Protein Name | glypican 6 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 555 |
| Uniprot ID | Q9ULV3 |
| Ensembl Protein ID | ENSP00000362029 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam01153 | 22-554 | Glypican |
| cl12245 | 22-554 | Glypican superfamily |
Ontology Information
| HPRD ID | 5117 |
|---|---|
| Molecular Class | Growth factor |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.