Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20952268 | 2011 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | Immunoblotting | Up-regulation | - | Excreted Fem1b protein fragments may be a useful biomarker for epithelial Wnt signaling and early intestinal neoplasia. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Ankyrin repeat domain containing |
| Description | This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. |
| Chromosome | 15 |
| Location | 15q22 |
| Start | 68277756 |
| End | 68295865 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 18110 |
| OMIM ID | 613539 |
| HGNC ID | HGNC:3649 |
| Unigene ID | Hs.362733 |
| Ensembl ID | ENSG00000169018 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | XM_006720370.2 |
|---|---|
| Exon | join(1..910,11852..12732,12955..18110) | mRNA Sequence | Download Select all |
| Length | 7132 |
CDS Information
| Location | join(663..910,11852..13487) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS10228.1 |
Protein Information
| Protein ID | NP_056137.1 |
|---|---|
| Protein Name | fem-1 homolog b (C. elegans) |
| Molecular Wt. (Da) | 70133 |
| Protein Sequence | Download Select all |
| Length | 627 |
| Uniprot ID | P10914 |
| Ensembl Protein ID | ENSP00000245414 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 317 | APAF1 | 3755 | NP_863651.1 | in vitro;in vivo | 10764728 |
| 355 | FAS | 609 | NP_000034.1 | in vitro;in vivo;yeast 2-hybrid | 10542291 |
| 9856 | KIAA0319 | 18713 | NP_055624.2 | yeast 2-hybrid | 12421765 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00204 | 87-207 | ANK |
| cl02529 | 87-207 | ANK superfamily |
| cd00204 | 478-577 | ANK |
| cl02529 | 478-577 | ANK superfamily |
| cd00204 | 115-239 | ANK |
| cd00204 | 48-174 | ANK |
| cd00204 | 149-241 | ANK |
| cd00204 | 471-578 | ANK |
| pfam00023 | 87-118 | Ank |
| pfam00023 | 155-183 | Ank |
| cd00204 | 471-545 | ANK |
| smart00248 | 153-182 | ANK |
| smart00248 | 87-115 | ANK |
| pfam00023 | 187-213 | Ank |
| pfam13606 | 153-182 | Ank_3 |
| pfam00023 | 123-152 | Ank |
| pfam13606 | 87-116 | Ank_3 |
| pfam00023 | 48-68 | Ank |
| cl02529 | 48-68 | ANK superfamily |
| pfam12796 | 92-183 | Ank_2 |
| pfam12796 | 158-247 | Ank_2 |
| pfam13637 | 46-108 | Ank_4 |
| pfam13857 | 518-578 | Ank_5 |
| pfam12796 | 125-216 | Ank_2 |
| pfam12796 | 50-151 | Ank_2 |
| PHA03100 | 47-243 | PHA03100 |
| COG0666 | 47-208 | ANKYR |
| COG0666 | 18-175 | ANKYR |
| PHA02878 | 59-226 | PHA02878 |
| PHA03095 | 102-249 | PHA03095 |
| pfam12796 | 32-117 | Ank_2 |
| PHA03100 | 102-239 | PHA03100 |
| pfam13637 | 155-207 | Ank_4 |
| PHA02874 | 49-241 | PHA02874 |
| PHA02874 | 85-243 | PHA02874 |
| PHA03095 | 101-249 | PHA03095 |
| PHA02875 | 48-208 | PHA02875 |
| pfam13637 | 121-174 | Ank_4 |
| PHA02875 | 85-264 | PHA02875 |
| PHA02876 | 86-242 | PHA02876 |
| PTZ00322 | 162-245 | PTZ00322 |
| PHA03100 | 101-182 | PHA03100 |
| COG0666 | 143-289 | ANKYR |
| PHA03100 | 133-253 | PHA03100 |
| PLN03192 | 88-207 | PLN03192 |
| PHA02798 | 101-218 | PHA02798 |
| pfam13637 | 90-141 | Ank_4 |
| PHA03095 | 102-208 | PHA03095 |
| PLN03192 | 48-179 | PLN03192 |
| PHA03095 | 100-227 | PHA03095 |
| pfam13857 | 140-194 | Ank_5 |
| TIGR00870 | 11-239 | trp |
| PHA02878 | 95-264 | PHA02878 |
| PLN03192 | 89-316 | PLN03192 |
| PTZ00322 | 104-174 | PTZ00322 |
| PHA03095 | 475-613 | PHA03095 |
| pfam13857 | 107-161 | Ank_5 |
| PHA02876 | 48-272 | PHA02876 |
| COG0666 | 489-578 | ANKYR |
| pfam13857 | 173-226 | Ank_5 |
| PHA03100 | 83-153 | PHA03100 |
| pfam12796 | 478-570 | Ank_2 |
| PHA02876 | 48-179 | PHA02876 |
| pfam13637 | 189-239 | Ank_4 |
| PHA02875 | 46-163 | PHA02875 |
| PHA02874 | 475-580 | PHA02874 |
| PHA03095 | 516-585 | PHA03095 |
| PHA03100 | 423-577 | PHA03100 |
| PHA03100 | 465-552 | PHA03100 |
| PHA02874 | 103-239 | PHA02874 |
| PHA02876 | 134-216 | PHA02876 |
| PHA02989 | 102-225 | PHA02989 |
| PTZ00322 | 54-140 | PTZ00322 |
| PLN03192 | 134-350 | PLN03192 |
| PHA03100 | 493-581 | PHA03100 |
| PHA02798 | 131-271 | PHA02798 |
| PHA02878 | 512-590 | PHA02878 |
| PHA02878 | 510-587 | PHA02878 |
Ontology Information
| HPRD ID | 3543 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.