Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CITED2 | 10370 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 6 | MRG1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18054336 | 2007 | Cell line : RKO Source : ATCC Sample Type : - No. of Sample : - Stage : - | Reporter assay,si RNA RT-PCR,Matrigel invasion assay,Confocal microscopy | Up-regulation | - | CITED2 regulates colon cancer invasion and might be a target for HDAC inhibitor-based intervention of colon cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
| Chromosome | 6 |
| Location | 6q23.3 |
| Start | 139693392 |
| End | 139695787 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 2396 |
| OMIM ID | 602937 |
| HGNC ID | HGNC:1987 |
| Unigene ID | Hs.82071 |
| Ensembl ID | ENSG00000164442 |
| PharmGKB ID | PA26524 |
Protein Information
| Protein ID | NP_001161860.1 |
|---|---|
| Protein Name | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 270 |
| Uniprot ID | Q8TDI0 |
| Ensembl Protein ID | ENSP00000262450 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1387 | CREBBP | 2534 | NP_004371.2 | in vivo | 9887100 |
| 2033 | EP300 | 4078 | NP_001420.2 | in vitro;in vivo;yeast 2-hybrid | 98 871 001 258 684 000 000 000 |
| 3091 | HIF1A | 4517 | NP_001521.1 | in vitro | 12778114 |
| 7020 | TFAP2A | 128 | NP_003211.1 | in vitro;in vivo;yeast 2-hybrid | 12586840 |
| 7022 | TFAP2C | 3361 | NP_003213.1 | in vitro;in vivo;yeast 2-hybrid | 1 258 684 011 744 730 |
| 8022 | LHX3 | 2783 | NP_055379.1 | in vivo;yeast 2-hybrid | 10593900 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 5917 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | RNA binding (GO:0003723) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.