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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
GNB2L1 10399 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1  5Gnb2-rs1, RACK1, H12.3 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24504450   2014Cell line : -

Source : West China hoppital Sichuang, china.

Sample Type : Population basedcCase control study

No. of Sample : 157

Stage : -

RT-PCR, Western-blotting, immunohistochemistryUp-regulation--


Gene Details



NC_000005.9 (180663928..180671209, complement)

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Gene Type protein coding
Gene Family WD repeat domain containing
Description -  
Chromosome 5
Location 5q35.3
Start 180663928  
End 180671209  
Strand -  
Gene Sequence

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Length 7282  
OMIM ID 176981   
HGNC ID HGNC:4399   
Unigene ID Hs.5662   
Ensembl ID -   
PharmGKB ID PA28779   

mRNA Information


mRNA ID ?NM_006098.4
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS34324.1



Protein Information


      
Protein IDNP_006089.1
Protein Nameguanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Molecular Wt. (Da)0
Protein Sequence

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Length 317  
Uniprot IDQ9UKR3
Ensembl Protein ID ENSP00000334079  



Post-translational Modification Information (Source : HPRD)


Residue Type site
YPhosphorylation228;-
TAcetylation2
KAcetylation130
CS-Nitrosylation249
TPhosphorylation316
TPhosphorylation6
TPhosphorylation313
TPhosphorylation2

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
1439CSF2RB739NP_000386.1in vivo;yeast 2-hybrid10490850   
1759DNM13851NP_004399.2in vitro12359736   
2057EPOR587NP_000112.1in vitro;in vivo12960323   
2534FYN655NP_002028.1in vitro;in vivo1   194   384   812   524   440   
2562GABRB38844NP_068712.1in vitro14724252   
2782GNB1766NP_002065.1in vitro12359736   
2904GRIN2B697NP_000825.2in vitro;in vivo12524444   
3454IFNAR1126NP_000620.2in vitro;in vivo11301323   
3480IGF1R932NP_000866.1in vitro;in vivo;yeast 2-hybrid1   188   461   816   382   130   
3560IL2RB896NP_000869.1in vitro;in vivo12960323   
3566IL4R990NP_000409.1in vitro;in vivo12960323   
3643INSR975NP_000199.2in vitro;in vivo16382134   
3688ITGB1628NP_391987.1in vitro;in vivo;yeast 2-hybrid9442085   
3693ITGB5949NP_002204.2in vitro;in vivo;yeast 2-hybrid9442085   
3695ITGB7948NP_000880.1in vitro;in vivo;yeast 2-hybrid9765275   
3716JAK1992NP_002218.2in vitro;in vivo12960323   
4772NFATC12729NP_765975.1in vivo;yeast 2-hybrid12521306   
5335PLCG11398NP_002651.2in vitro;in vivo8290562   
5578PRKCA1498NP_002728.1in vivo12435334   
5579PRKCB1499NP_002729.2in vitro;in vivo10480917   
5580PRKCD1501NP_006245.2in vivo11884618   
5581PRKCE1500NP_005391.1in vitro;in vivo1   195   621   111   709   410   
5587PRKD15668NP_002733.2in vivo11884618   
5797PTPRM1479NP_001098714.1in vitro;in vivo;yeast 2-hybrid11278757   
5921RASA1745NP_002881.1in vitro;in vivo11350068   
6531SLC6A3543NP_001035.1in vitro;in vivo;yeast 2-hybrid15202772   
6774STAT326NP_644805.1in vitro;in vivo16382134   
7297TYK21490NP_003322.3in vitro;in vivo12960323   
11269DDX19B5781NP_009173.1yeast 2-hybrid16169070   
28965SLC27A69173NP_054750.1yeast 2-hybrid16169070   
51280GOLM18428NP_057632.2yeast 2-hybrid16169070   
81628TSC22D418231NP_112197.1yeast 2-hybrid16189514   


Pathway Information


      
Pathway Name Pathway ID
Measles hsa05162


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd002007-311  WD40
cl025677-311  WD40 superfamily
cd002002-133  WD40
pfam0040095-133  WD40
smart0032094-133  WD40
pfam0040053-91  WD40
smart0032053-91  WD40
pfam00400145-178  WD40
pfam00400182-220  WD40
smart00320145-178  WD40
smart00320190-220  WD40
pfam00400May-44  WD40
smart00320Apr-44  WD40
pfam00400286-310  WD40
COG23192-310  WD40
COG231910-283  WD40
COG231932-315  WD40
COG231962-310  WD40
PLN0018180-222  PLN00181
PLN0018131-261  PLN00181
PLN00181108-314  PLN00181
PTZ00421102-213  PTZ00421
PLN0018111-133  PLN00181
PTZ0042111-131  PTZ00421
PTZ00420Nov-92  PTZ00420


Ontology Information


   
HPRD ID15585
Molecular ClassAdapter molecule
Molecular FunctionLigase activity (GO:0016874)
Biological ProcessProtein modification (GO:0006464)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO