Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PDPN | 10630 | podoplanin | 1 | T1A-2, Gp38, aggrus, GP40, PA2.26 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19556810 | 2009 | Cell line : HCT116, HCT15 Source : National Cancer Center Hospital, Tokyo, Japan. Sample Type : CRC tumor and normal tissue No. of Sample : 120 Stage : - | DNA microarray , Immunohistochemistry,coculture invasion assay,Univariate analysis | Down-regulation | - | Positive podoplanin expression in stromal fibroblasts could have a protective role against CRC cell invasion and is a significant indicator of a good prognosis in patients with advanced CRC. |
| 24015033 | 2013 | Cell line : - Source : Department of Pathology of the Chungbuk National University Hospital. Sample Type : Paraffin-embedded tissues No. of Sample : - Stage : AJCC Stage I-IV. | Tissue microarray and immunohistochemistry | Down-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Chromosome | 1 |
| Location | 1p36.21 |
| Start | 13910252 |
| End | 13944452 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 34201 |
| OMIM ID | 608863 |
| HGNC ID | HGNC:29602 |
| Unigene ID | Hs.468675 |
| Ensembl ID | ENSG00000162493 |
| PharmGKB ID | PA142671187 |
Protein Information
| Protein ID | NP_001006625.1 |
|---|---|
| Protein Name | podoplanin |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 162 |
| Uniprot ID | Q7KZF4 |
| Ensembl Protein ID | ENSP00000346762 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam05808 | 1-162 | Podoplanin |
| cl05402 | 1-162 | Podoplanin superfamily |
Ontology Information
| HPRD ID | 12062 |
|---|---|
| Molecular Class | Water channel |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.