Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DNAJB4 | 11080 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 1 | HLJ1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24696714 | 2014 | Cell line : - Source : Affiliated Hospital of Luzhou Medical College Sample Type : CRC tumor and normal tissue No. of Sample : 120 Stage : Duke stage A-D | Real time RT-PCR, Western blotting, Immunohistochemistry | Down-regulation | - | HLJ1 is a strong tumor suppressor for CRC, and thus the down-regulation of the HLJ1 expression may be used as a biomarker to predict clinical outcome of patients with CRC. HLJ1 expression was significantly down-regulated in CRC or lymphatic metastatic tissues from patient, compared to that in the normal mucosa and the HLJ1 expression was correlated strongly with lymph metastasis, Dukes' stage, and remote metastasis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Heat shock proteins / DNAJ (HSP40) |
| Description | DNAJB4 belongs to the evolutionarily conserved DNAJ/HSP40 protein family. For background information on the DNAJ family, see MIM 608375.[ |
| Chromosome | 1 |
| Location | 1p31.1 |
| Start | 77979217 |
| End | 78018721 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 39505 |
| OMIM ID | 611327 |
| HGNC ID | HGNC:14886 |
| Unigene ID | Hs.13852 |
| Ensembl ID | ENSG00000162616 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | XM_005270397.2 |
|---|---|
| Exon | join(1..77,33835..34403,36798..39505) | mRNA Sequence | Download Select all |
| Length | 2250 |
CDS Information
| Location | join(25895..26105,33835..34403,36798..37031) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS684.1 |
Protein Information
| Protein ID | NP_008965.2 |
|---|---|
| Protein Name | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| Molecular Wt. (Da) | 37676 |
| Protein Sequence | Download Select all |
| Length | 337 |
| Uniprot ID | P26010 |
| Ensembl Protein ID | ENSP00000267082 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 122 |
| T | Phosphorylation | 223 |
| Y | Phosphorylation | 252 |
| S | Phosphorylation | 38 |
| S | Phosphorylation | 148 |
| S | Phosphorylation | 133 |
| S | Phosphorylation | 138 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd10747 | 158-322 | DnaJ_C |
| cl21722 | 158-322 | DnaJ_C superfamily |
| cd06257 | Apr-57 | DnaJ |
| cl02542 | Apr-57 | DnaJ superfamily |
| pfam00226 | Apr-65 | DnaJ |
| smart00271 | Mar-60 | DnaJ |
| pfam01556 | 249-328 | CTDII |
| COG0484 | 1-332 | DnaJ |
| TIGR02349 | 4-332 | DnaJ_bact |
| PTZ00037 | 3-336 | PTZ00037 |
| PRK10767 | 1-332 | PRK10767 |
| PRK14286 | 3-332 | PRK14286 |
| PRK14289 | 3-332 | PRK14289 |
| PRK14291 | 1-319 | PRK14291 |
| PRK14293 | 1-332 | PRK14293 |
| PRK14299 | 3-332 | PRK14299 |
| PRK14298 | 3-332 | PRK14298 |
| PRK14283 | 3-332 | PRK14283 |
| PRK14301 | 1-332 | PRK14301 |
| PRK14277 | 1-332 | PRK14277 |
| PRK14281 | 1-331 | PRK14281 |
| PRK14297 | 3-337 | PRK14297 |
| PRK14292 | 4-330 | PRK14292 |
| PRK14294 | 3-330 | PRK14294 |
| PRK14295 | 3-337 | PRK14295 |
| PRK14280 | 1-332 | PRK14280 |
| PRK14278 | 1-332 | PRK14278 |
| PRK14282 | 3-331 | PRK14282 |
| PRK14276 | 3-337 | PRK14276 |
| PRK14279 | 3-336 | PRK14279 |
| PRK14284 | 4-332 | PRK14284 |
| PRK14287 | 3-332 | PRK14287 |
| PRK14290 | 1-332 | PRK14290 |
| PRK10266 | 3-319 | PRK10266 |
| PRK14296 | 3-332 | PRK14296 |
| PRK14300 | 1-332 | PRK14300 |
| COG2214 | 3-251 | CbpA |
| PRK14285 | 1-330 | PRK14285 |
| PRK14288 | 1-332 | PRK14288 |
| TIGR03835 | Mar-72 | termin_org_DnaJ |
| COG5407 | Apr-68 | SEC63 |
| PTZ00341 | May-73 | PTZ00341 |
| COG5269 | Apr-65 | ZUO1 |
| PHA03102 | Sep-69 | PHA03102 |
| PRK09430 | Mar-55 | djlA |
| PHA02624 | Sep-61 | PHA02624 |
| PRK01356 | Apr-64 | hscB |
| COG1076 | 20-64 | DjlA |
| COG1076 | Apr-53 | DjlA |
Ontology Information
| HPRD ID | 992 |
|---|---|
| Molecular Class | Heat shock protein |
| Molecular Function | Protein-tyrosine kinase activity (GO:0004713) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.