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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
STRAP 11171 serine/threonine kinase receptor associated protein  12UNRIP, pt-wd, MAWD 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
17316412   2007Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 59 colonic adenomas and 123 CRC

Stage : -

ImmunohistochemistryUp-regulation-Upregulation of STRAP might play a role in tumor development as an early event for colorectal cancers.


Gene Details



NC_000012.11 (16035288..16056412)

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Gene Type protein coding
Gene Family WD repeat domain containing
Description -  
Chromosome 12
Location 12p13.1
Start 16035288  
End 16056412  
Strand +  
Gene Sequence

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Length 21125  
OMIM ID 605986   
HGNC ID HGNC:30796   
Unigene ID Hs.743971   
Ensembl ID ENSG00000023734   
PharmGKB ID PA134867032   

mRNA Information


mRNA ID ?NM_007178.3
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS8676.1



Protein Information


      
Protein IDNP_009109.3
Protein Nameserine/threonine kinase receptor associated protein
Molecular Wt. (Da)0
Protein Sequence

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Length 350  
Uniprot IDQ96T88
Ensembl Protein ID ENSP00000484739  



Post-translational Modification Information (Source : HPRD)


Residue Type site
TPhosphorylation325
TPhosphorylation326
SPhosphorylation335
SPhosphorylation338

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                  
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
4087SMAD23221NP_005892.1in vitro;in vivo10757800   
4088SMAD34380NP_005893.1in vitro;in vivo10757800   
4091SMAD64240NP_005576.3in vitro;in vivo10757800   
4092SMAD74241NP_005895.1in vitro;in vivo10757800   
6606SMN12646NP_000335.1in vitro;in vivo15848170   
6628SNRPB1655NP_937859.1in vitro15848170   
6633SNRPD23038NP_004588.1in vitro15848170   
6634SNRPD33039NP_004166.1in vitro15848170   
6635SNRPE548NP_003085.1in vitro15848170   
7046TGFBR11822NP_004603.1in vitro;in vivo;yeast 2-hybrid9856985   
7048TGFBR21823NP_001020018.1in vitro;in vivo;yeast 2-hybrid9856985   
51250C6orf20312873NP_001135942.1yeast 2-hybrid16169070   
79760GEMIN77600NP_078983.1in vitro15848170   
79833GEMIN66110NP_079051.9in vitro15848170   


Pathway Information


      
Pathway Name Pathway ID
RNA transport hsa03013


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd002009-293  WD40
cl025679-293  WD40 superfamily
cd0020099-302  WD40
smart00320254-292  WD40
pfam00400255-292  WD40
pfam0040098-128  WD40
smart0032090-128  WD40
smart00320137-170  WD40
pfam00400137-170  WD40
smart00320Sep-40  WD40
COG231911-292  WD40
COG231954-292  WD40
COG231911-298  WD40
COG23198-305  WD40
COG23192-186  WD40
PLN0018197-292  PLN00181
PLN0018185-193  PLN00181


Ontology Information


   
HPRD ID17966
Molecular ClassCell cycle control protein
Molecular FunctionDNA binding (GO:0003677)
Biological ProcessDNA replication (GO:0006260)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO