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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PDAP1 | 11333 | PDGFA associated protein 1 | 7 | PAP1, PAP, HASPP28 |
- Evidence
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- mRNA
- CDS
- Protein
- PTM
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- PPi
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21331762 | 2011 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 12 Stage : - | DNA sequencing, suppressive subtractive hybridization, real time RT-PCR | Up-regulation | - | ST3GAL5, IFITM3, PDAP1, ALKBH3, NUDT14, CNN2, MAPK14, ACO1, and SEPHS1 may be involved in rectal carcinogenesis. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. [provided by RefSeq, Dec 2010] |
| Chromosome | 7 |
| Location | 7q |
| Start | 98992296 |
| End | 99006305 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 14010 |
| OMIM ID | 607075 |
| HGNC ID | HGNC:14634 |
| Unigene ID | Hs.632296 |
| Ensembl ID | ENSG00000106244 |
| PharmGKB ID | PA33102 |
Protein Information
| Protein ID | NP_055706.1 |
|---|---|
| Protein Name | PDGFA associated protein 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 181 |
| Uniprot ID | Q9NPH5 |
| Ensembl Protein ID | ENSP00000263317 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 60 |
| S | Phosphorylation | 63 |
| S | Phosphorylation | 63;- |
| S | Phosphorylation | 57;- |
| S | Phosphorylation | 19 |
| S | Phosphorylation | 176 |
| S | Phosphorylation | 178 |
| Y | Phosphorylation | 70 |
| Y | Phosphorylation | 17 |
| K | Acetylation | 132 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5154 | PDGFA | 1424 | NP_002598.4 | in vitro | 8780057 |
| 5155 | PDGFB | 1815 | NP_002599.1 | in vitro | 8780057 |
| 5159 | PDGFRB | 1423 | NP_002600.1 | in vitro | 11331882 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 5809 |
|---|---|
| Molecular Class | Secreted polypeptide |
| Molecular Function | GTPase activator activity (GO:0005096) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.