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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22641666 | 2012 | Cell line : HCT116, HCT15, DLD-1, SW48, LS180, Colo201 Source : ATCC Sample Type : - No. of Sample : - Stage : - | real time RT-PCR,Cell proliferation assay,Immunoprecipitation, western blotting,Microarray | Down-regulation | - | ALPK2, down-regulated by oncogenic KRAS, is crucial for luminal apoptosis and expression of DNA repair-related genes, possibly in the transition of normal colonic crypt to adenoma. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Immunoglobulin superfamily / I-set domain containing |
| Description | - |
| Chromosome | 18 |
| Location | 18q21.31 |
| Start | 56148479 |
| End | 56296189 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 147711 |
| OMIM ID | - |
| HGNC ID | HGNC:20565 |
| Unigene ID | Hs.628152 |
| Ensembl ID | ENSG00000198796 |
| PharmGKB ID | PA134916108 |
Protein Information
| Protein ID | NP_443179.3 |
|---|---|
| Protein Name | alpha-kinase 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 2170 |
| Uniprot ID | Q5SGD2 |
| Ensembl Protein ID | ENSP00000295839 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00096 | 29-101 | Ig |
| cl11960 | 29-101 | Ig superfamily |
| cd00096 | 1804-1872 | Ig |
| cl11960 | 1804-1872 | Ig superfamily |
| smart00811 | 1905-2125 | Alpha_kinase |
| cl03728 | 1905-2125 | Alpha_kinase superfamily |
| pfam02816 | 1925-2125 | Alpha_kinase |
| cd05748 | 35-104 | Ig_Titin_like |
| cd04978 | 27-104 | Ig4_L1-NrCAM_like |
| cd05729 | 23-104 | Ig2_FGFR_like |
| cd05893 | 31-104 | Ig_Palladin_C |
| cd05723 | 28-102 | Ig4_Neogenin |
| cd05744 | 31-104 | Ig_Myotilin_C_like |
| pfam13895 | 17-104 | Ig_2 |
| cd05867 | 29-104 | Ig4_L1-CAM_like |
| cd05731 | 30-105 | Ig3_L1-CAM_like |
| cd05857 | 23-96 | Ig2_FGFR |
| cd05728 | 33-104 | Ig4_Contactin-2-like |
| cd05868 | 28-104 | Ig4_NrCAM |
| cd05725 | 29-104 | Ig3_Robo |
| cd05891 | 25-94 | Ig_M-protein_C |
| cd05737 | 31-94 | Ig_Myomesin_like_C |
| cd07693 | 23-94 | Ig1_Robo |
| cd05760 | 30-99 | Ig2_PTK7 |
| cd05856 | 24-104 | Ig2_FGFRL1-like |
| cd05724 | 29-94 | Ig2_Robo |
| cd05892 | 31-104 | Ig_Myotilin_C |
| cd05747 | Nov-94 | Ig5_Titin_like |
| pfam13895 | 1801-1874 | Ig_2 |
| cd05760 | 1804-1880 | Ig2_PTK7 |
| cd05736 | 29-95 | Ig2_Follistatin_like |
| pfam07679 | 14-104 | I-set |
| smart00408 | 1802-1865 | IGc2 |
| smart00410 | 20-104 | IG_like |
| smart00409 | 20-104 | IG |
| smart00408 | 25-94 | IGc2 |
| smart00410 | 1802-1874 | IG_like |
| smart00409 | 1802-1874 | IG |
| pfam07679 | 1804-1874 | I-set |
Ontology Information
| HPRD ID | 13248 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.