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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
ARL11 115761 ADP-ribosylation factor-like 11  13ARLTS1, FLJ33930 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
21819567   2011Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : Stage 1 515 CRC and 515 controls, stage 2 901 CRC and 909 controls

Stage : Stage I,III

GenotypingPolymorhpism-ARL11, ADH1C, GALNTL2 and IL6 genetic variants may have an effect on CRC risk.


Gene Details



NC_000013.10 (50202435..50208008)

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Gene Type protein coding
Gene Family ADP-ribosylation factors-like, "ADP-ribosylation factors"
Description This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010]  
Chromosome 13
Location 13q14.12
Start 50202435  
End 50208008  
Strand +  
Gene Sequence

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Length 5574  
OMIM ID 609351   
HGNC ID HGNC:24046   
Unigene ID Hs.558599   
Ensembl ID ENSG00000152213   
PharmGKB ID PA134974627   

mRNA Information


mRNA ID ?NM_138450.5
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS9419.1



Protein Information


      
Protein IDNP_612459.1
Protein NameADP-ribosylation factor-like 11
Molecular Wt. (Da)0
Protein Sequence

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Length 196  
Uniprot IDQ7Z7J5
Ensembl Protein ID ENSP00000417710  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0415614-172  ARLTS1
cl2145514-172  P-loop_NTPase superfamily
pfam000251-169  Arf
cd0087814-167  Arf_Arl
cd041538-166  Arl5_Arl8
cd0415510-166  Arl3
cd0415215-184  Arl4_Arl7
cd0414912-166  Arf6
cd0415412-166  Arl2
cd0415114-169  Arl1
smart0017710-175  ARF
PLN0022310-177  PLN00223
PTZ0013310-177  PTZ00133
cd0415014-169  Arf1_5_like
cd0087910-169  Sar1
cd0416015-165  Arfrp1
cd0415714-169  Arl6
cd0415915-169  Arl10_like
cd0415814-169  ARD1
cd0416115-161  Arl2l1_Arl13_like
cd0416214-173  Arl9_Arfrp2_like
cd0088216-169  Ras_like_GTPase
cd0410515-142  SR_beta
COG222910-169  Srp102
cd0088019-173  Era_like
cd0189878-173  Obg
pfam0847715-125  Miro
cd0015415-169  Rab
cd0991412-164  RocCOR
cd0187823-169  HflX
cd0410813-178  Rab36_Rab34
pfam0192614-123  MMR_HSR1
cd0411316-165  Rab4
cd0411614-128  Rab9
cd0410914-127  Rab28
cd0186314-169  Rab18
PRK0045470-174  engB
cd0411014-128  Rab35
cd0412216-165  Rab14
cd0412914-162  Rho2
cd0416471-168  trmE
smart0017415-164  RHO
smart0017812-169  SAR
COG110012-143  Gem1
TIGR0023112-129  small_GTP
pfam0943915-142  SRPRB
PRK1229978-175  obgE
COG053215-169  InfB
TIGR0272978-173  Obg_CgtA
PLN03118Jan-91  PLN03118
TIGR0048715-191  IF-2
COG226214-169  HflX
PRK1229779-175  obgE
COG053678-176  Obg
pfam0467015-93  Gtr1_RagA
pfam0007115-123  Ras
pfam0050341-123  G-alpha
TIGR0315623-169  GTP_HflX


Ontology Information


   
HPRD ID6392
Molecular ClassGTPase
Molecular FunctionReceptor activity (GO:0004872)
Biological ProcessImmune response (GO:0006955)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO