Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CTHRC1 | 115908 | collagen triple helix repeat containing 1 | 8 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24504172 | 2014 | Cell line : SW480, HT-29 Source : Samsung Medical Center . Sample Type : CRC tumor and normal tissue No. of Sample : 188 Stage : - | real time RT-PCR,immunohistochemistry,Bisulfite sequencing,Pyrosequencing, Western Blotting | Up-regulation | - | High levels of CTHRC1 expression are associated with poor clinical outcomes. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012] |
| Chromosome | 8 |
| Location | 8q22.3 |
| Start | 104383743 |
| End | 104395233 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 11491 |
| OMIM ID | 610635 |
| HGNC ID | HGNC:18831 |
| Unigene ID | Hs.405614 |
| Ensembl ID | ENSG00000164932 |
| PharmGKB ID | PA38701 |
Protein Information
| Protein ID | NP_001243028.1 |
|---|---|
| Protein Name | collagen triple helix repeat containing 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 243 |
| Uniprot ID | Q7Z6A9 |
| Ensembl Protein ID | ENSP00000333919 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam01391 | 57-89 | Collagen |
| cl22949 | 57-89 | Collagen superfamily |
| pfam01391 | 58-92 | Collagen |
| pfam01391 | 58-92 | Collagen |
| pfam01391 | 58-92 | Collagen |
| pfam01391 | 57-92 | Collagen |
| pfam01391 | 56-91 | Collagen |
| pfam01391 | 56-91 | Collagen |
| pfam01391 | 57-93 | Collagen |
Ontology Information
| HPRD ID | 17819 |
|---|---|
| Molecular Class | Extracellular matrix protein |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.