Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| LRRC3B | 116135 | leucine rich repeat containing 3B | 3 | LRP15 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18815942 | 2009 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | Microarray, methylation-specific PCR , real timeRT- PCR | Methylation | - | LRRC3B methylation has significant tumor specificity and may be a biomarker of CRC. LRRC3B may be a novel methylation-sensitive tumor suppressor gene in CRC. LRRC3B methylation intensity was significantly higher in cancer tissues than in the corresponding non-cancerous tissues. Decreased LRRC3B expression (17/31, 55%) was observed in the cancer tissues by real-time PCR. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | - |
| Chromosome | 3 |
| Location | 3p24 |
| Start | 26622809 |
| End | 26710776 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 87968 |
| OMIM ID | |
| HGNC ID | HGNC:28105 |
| Unigene ID | Hs.517868 |
| Ensembl ID | ENSG00000179796 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_052953.2 |
|---|---|
| Exon | join(1..429,86705..87968) | mRNA Sequence | Download Select all |
| Length | 1718 |
Protein Information
| Protein ID | NP_443185.1 |
|---|---|
| Protein Name | leucine rich repeat containing 3B |
| Molecular Wt. (Da) | 25475 |
| Protein Sequence | Download Select all |
| Length | 259 |
| Uniprot ID | P28300 |
| Ensembl Protein ID | ENSP00000231004 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00013 | 33-68 | LRRNT |
| cl02423 | 33-68 | LRRNT superfamily |
| pfam01462 | 33-63 | LRRNT |
| pfam12799 | 69-104 | LRR_4 |
| cl19302 | 69-104 | LRR_4 superfamily |
| cd00116 | 67-125 | LRR_RI |
| cl23707 | 67-125 | LRR_RI superfamily |
| pfam13855 | 69-125 | LRR_8 |
| pfam13855 | 90-138 | LRR_8 |
| PRK15370 | 52-145 | PRK15370 |
| COG4886 | 39-135 | LRR |
| PRK15370 | 43-162 | PRK15370 |
| COG4886 | 54-147 | LRR |
| pfam13306 | 51-135 | LRR_5 |
| pfam13306 | 73-135 | LRR_5 |
Ontology Information
| HPRD ID | 1063 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transporter activity (GO:0005215) |
| Biological Process | Transport (GO:0006810) |
Drug Information
No matching records could be found.