Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CLC | 1178 | Charcot-Leyden crystal galectin | 19 | LGALS10, MGC149659, Gal-10 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21716316 | 2011 | Cell line : - Source : Hospitals located in the South East region of Norway. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Microarray | Up-regulation | - | CLC and IFNAR1 were identified to be overall differentially expressed between early- and late-onset CRC, and are important in the development of early-onset CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Lectins, galactoside-binding |
| Description | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008] |
| Chromosome | 19 |
| Location | 19q13.1 |
| Start | 40221893 |
| End | 40228669 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 6777 |
| OMIM ID | 153310 |
| HGNC ID | HGNC:2014 |
| Unigene ID | Hs.889 |
| Ensembl ID | ENSG00000105205 |
| PharmGKB ID | PA26541 |
mRNA Information
| mRNA ID | NM_001828.5 |
|---|---|
| Exon | join(1..92,2957..3033,3537..3747,6525..6777) | mRNA Sequence | Download Select all |
| Length | 649 |
Protein Information
| Protein ID | NP_001819.2 |
|---|---|
| Protein Name | Charcot-Leyden crystal galectin |
| Molecular Wt. (Da) | 16322 |
| Protein Sequence | Download Select all |
| Length | 142 |
| Uniprot ID | P30989 |
| Ensembl Protein ID | ENSP00000359532 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00070 | 5-135 | GLECT |
| cl00071 | 5-135 | GLECT superfamily |
| smart00276 | 12-138 | GLECT |
| pfam00337 | 5-137 | Gal-bind_lectin |
| smart00908 | 14-136 | Gal-bind_lectin |
Ontology Information
| HPRD ID | 3012 |
|---|---|
| Molecular Class | Enzyme: Phospholipase |
| Molecular Function | Transporter activity (GO:0005215) |
| Biological Process | Transport (GO:0006810) |
Drug Information
No matching records could be found.