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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
ASB9 140462 ankyrin repeat and SOCS box containing 9  XDKFZP564L0862, MGC4954, FLJ20636 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20878058   2010Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 125

Stage : -

real time RT-PCR, immunohistochemistry,proliferation and invasion assayUp-regulation-ASB9 mRNA expression was higher in CRC tissue than corresponding normal tissue and Patients expressing low levels of ASB9 had a poorer overall survival rate than those expressing high levels.


Gene Details



NC_000023.10 (15262109..15288589, complement)

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Gene Type protein coding
Gene Family Ankyrin repeat domain containing
Description This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]  
Chromosome X
Location Xp22.2
Start 15262109  
End 15288589  
Strand -  
Gene Sequence

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Length 26481  
OMIM ID 300890   
HGNC ID HGNC:17184   
Unigene ID Hs.19404   
Ensembl ID ENSG00000102048   
PharmGKB ID PA25037   

mRNA Information


mRNA ID ?NM_001031739.2
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS14163.1



Protein Information


      
Protein IDNP_001026909.1
Protein Nameankyrin repeat and SOCS box containing 9
Molecular Wt. (Da)0
Protein Sequence

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Length 294  
Uniprot IDQ96RK1
Ensembl Protein ID ENSP00000361721  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
55662HIF1AN9426NP_060372.2yeast 2-hybrid16189514   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0020463-187  ANK
cl0252963-187  ANK superfamily
cd03728253-294  SOCS_ASB_9_11
cl02533253-294  SOCS superfamily
cd0020437-154  ANK
cd00204136-235  ANK
cd03716253-293  SOCS_ASB_like
cd03587255-293  SOCS
pfam07525255-292  SOCS_box
smart00969256-293  SOCS_box
cd03720255-293  SOCS_ASB1
cd03724255-291  SOCS_ASB5
cd03729255-294  SOCS_ASB13
cd03721253-293  SOCS_ASB2
cd03717253-292  SOCS_SOCS_like
cd03718255-293  SOCS_SSB1_4
cd03723255-292  SOCS_ASB4_ASB18
pfam0002371-96  Ank
smart0024868-96  ANK
cd03743255-291  SOCS_SSB4
smart00253252-292  SOCS
pfam00023136-163  Ank
pfam00023169-195  Ank
smart00248169-194  ANK
cd03731253-293  SOCS_ASB15
cd03744255-293  SOCS_SSB1
cd03726255-293  SOCS_ASB7
cd03730253-293  SOCS_ASB14
pfam1360671-96  Ank_3
smart00248136-161  ANK
pfam00023103-128  Ank
pfam12796106-194  Ank_2
pfam1279641-128  Ank_2
pfam1279673-163  Ank_2
pfam12796138-229  Ank_2
PHA0287638-236  PHA02876
PHA0287445-236  PHA02874
COG066615-197  ANKYR
PHA0287885-239  PHA02878
PHA0310017-230  PHA03100
PHA0287451-237  PHA02874
PLN0319243-193  PLN03192
PHA0287538-194  PHA02875
pfam1279638-96  Ank_2
PHA0287537-225  PHA02875
PHA0310055-167  PHA03100
PHA0287830-183  PHA02878
PHA0287540-235  PHA02875
pfam1363769-122  Ank_4
pfam12796171-235  Ank_2
PTZ0032242-132  PTZ00322
PHA0287438-236  PHA02874
PHA0287655-229  PHA02876
PHA0287852-209  PHA02878
PHA0309572-236  PHA03095
pfam1363737-89  Ank_4
PHA03095147-235  PHA03095
PHA0287682-239  PHA02876
PHA03095118-236  PHA03095
COG0666129-284  ANKYR
pfam13637102-154  Ank_4
PHA0309552-235  PHA03095
pfam13637136-187  Ank_4
TIGR0087094-227  trp
PHA02875106-238  PHA02875
PHA0287440-141  PHA02874
PHA0287650-129  PHA02876
PHA0287636-128  PHA02876
PHA02884104-184  PHA02884
PHA0309522-158  PHA03095
pfam1385755-109  Ank_5
PHA0287439-141  PHA02874
PHA0294652-239  PHA02946
PHA0279885-195  PHA02798
pfam13857121-174  Ank_5
PTZ00322183-238  PTZ00322
PHA03100160-235  PHA03100
PHA0287438-128  PHA02874
PHA0288434-106  PHA02884
PHA03095171-238  PHA03095
TIGR0087066-129  trp
PTZ00322153-243  PTZ00322
pfam13637169-218  Ank_4
PHA02884115-194  PHA02884
PHA02859169-235  PHA02859


Ontology Information


   
HPRD ID9921
Molecular ClassUnclassified
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO