Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| MAPK14 | 1432 | mitogen-activated protein kinase 14 | 6 | PRKM14, p38, Mxi2, PRKM15 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26185457 | 2015 | Cell line : - Source : Renji Hospital (Shanghai, People�s Republic of China). Sample Type : CRC tumor and normal tissue No. of Sample : 2 Stage : - | DNA methylation microarray | Hypermethylation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Mitogen-activated protein kinase cascade / Kinases |
| Description | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Chromosome | 6 |
| Location | 6p21.3-p21 |
| Start | 35995412 |
| End | 36079013 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 83602 |
| OMIM ID | 600289 |
| HGNC ID | HGNC:6876 |
| Unigene ID | Hs.485233 |
| Ensembl ID | ENSG00000112062 |
| PharmGKB ID | PA30621 |
mRNA Information
| mRNA ID | XM_011514311.1 |
|---|---|
| Exon | join(1..639,25065..25194,31655..31713,45239..45350, 46057..46086,46415..46462,48214..48328,48903..48974, 68353..68432,72618..72633,74937..75018) | mRNA Sequence | Download Select all |
| Length | 1383 |
Protein Information
| Protein ID | XP_011512613.1 |
|---|---|
| Protein Name | mitogen-activated protein kinase 14 |
| Molecular Wt. (Da) | 29482 |
| Protein Sequence | Download Select all |
| Length | 258 |
| Uniprot ID | O14638 |
| Ensembl Protein ID | ENSP00000350265 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 180 |
| Y | Phosphorylation | 182 |
| T | Phosphorylation | 180 |
| Y | Phosphorylation | 182 |
| T | Phosphorylation | 180 |
| Y | Phosphorylation | 182 |
| T | Phosphorylation | 180 |
| T | Phosphorylation | 180 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| T | Phosphorylation | 180;- |
| T | Phosphorylation | 180;- |
| T | Phosphorylation | 180;- |
| T | Phosphorylation | 180;- |
| T | Phosphorylation | 263;- |
| T | Phosphorylation | 263;- |
| T | Phosphorylation | 263;- |
| T | Phosphorylation | 175 |
| T | Phosphorylation | 175 |
| T | Phosphorylation | 175 |
| T | Phosphorylation | 175 |
| T | Phosphorylation | 298 |
| T | Phosphorylation | 298 |
| T | Phosphorylation | 241 |
| S | Phosphorylation | 2 |
| S | Phosphorylation | 2 |
| S | Phosphorylation | 2 |
| S | Phosphorylation | 2 |
| T | Phosphorylation | 16 |
| T | Phosphorylation | 16 |
| T | Phosphorylation | 16 |
| T | Phosphorylation | 16 |
| Y | Phosphorylation | 9 |
| Y | Phosphorylation | 9 |
| Y | Phosphorylation | 9 |
| Y | Phosphorylation | 9 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
| Y | Phosphorylation | 182 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 677 | ZFP36L1 | 3041 | NP_004917.2 | yeast 2-hybrid | 16189514 |
| 995 | CDC25C | 1146 | NP_001781.2 | in vitro | 1 133 398 610 557 090 000 000 000 000 000 |
| 1385 | CREB1 | 442 | NP_604391.1 | in vivo | 11377386 |
| 1386 | ATF2 | 443 | NP_001871.2 | in vitro;in vivo | 7 535 770 121 105 900 000 000 000 000 000 |
| 1459 | CSNK2A2 | 279 | NP_001887.1 | in vivo | 10747897 |
| 1460 | CSNK2B | 278 | NP_001311.3 | in vivo | 10747897 |
| 1649 | DDIT3 | 529 | NP_004074.2 | in vitro | 8650547 |
| 1978 | EIF4EBP1 | 3746 | NP_004086.1 | in vitro | 11777913 |
| 2002 | ELK1 | 2407 | NP_005220.2 | in vitro | 862 266 991 307 078 000 000 |
| 2004 | ELK3 | 2593 | NP_005221.2 | in vitro | 11042694 |
| 2099 | ESR1 | 589 | NP_000116.2 | in vitro;in vivo | 12138194 |
| 2316 | FLNA | 2060 | NP_001104026.1 | in vivo | 11390380 |
| 2885 | GRB2 | 150 | NP_002077.1 | in vitro | 8695800 |
| 3172 | HNF4A | 2612 | CAA89989.1 | in vitro | 16351573 |
| 3299 | HSF4 | 3896 | NP_001035757.1 | in vitro | 16581800 |
| 3726 | JUNB | 1303 | NP_002220.1 | in vitro | 98 891 988 917 518 |
| 3856 | KRT8 | 1015 | NP_002264.1 | in vitro;in vivo | 11 788 583 117 813 200 000 000 |
| 3875 | KRT18 | 1020 | NP_000215.1 | in vivo | 11788583 |
| 4088 | SMAD3 | 4380 | NP_005893.1 | in vitro;in vivo | 14512875 |
| 4141 | MARS | 8864 | NP_004981.2 | in vitro | 9878398 |
| 4149 | MAX | 1113 | NP_002373.3 | in vitro | 7479834 |
| 4205 | MEF2A | 2807 | NP_005578.2 | in vitro;in vivo | 10 330 143 985 852 800 000 000 |
| 4208 | MEF2C | 2809 | NP_002388.2 | in vitro;in vivo | 103 301 439 753 748 000 000 000 000 000 |
| 4687 | NCF1 | 1990 | NP_000256.3 | in vitro | 15629715 |
| 4772 | NFATC1 | 2729 | NP_765975.1 | in vitro;in vivo | 15304486 |
| 4776 | NFATC4 | 9096 | NP_001129494.1 | in vitro;in vivo | 11997522 |
| 5321 | PLA2G4A | 8986 | NP_077734.1 | in vivo | 9468497 |
| 5371 | PML | 23 | NP_150241.2 | in vitro;in vivo | 15273249 |
| 5594 | MAPK1 | 1496 | NP_002736.3 | in vitro | 1 269 781 017 255 940 |
| 5778 | PTPN7 | 1480 | NP_542155.1 | in vitro | 105 599 441 020 698 000 000 000 |
| 6334 | SCN8A | 9006 | NP_055006.1 | in vivo | 16014723 |
| 6548 | SLC9A1 | 123 | NP_003038.2 | in vitro;in vivo | 11604491 |
| 6775 | STAT4 | 2779 | NP_003142.1 | in vitro;in vivo | 10961885 |
| 6885 | MAP3K7 | 4011 | NP_663304.1 | in vivo | 12589052 |
| 8202 | NCOA3 | 3570 | NP_858045.1 | in vivo | 1 613 581 515 383 280 |
| 8411 | EEA1 | 5460 | NP_003557.2 | in vitro;in vivo | 16138080 |
| 8550 | MAPKAPK5 | 9467 | NP_620777.1 | in vitro | 9628874 |
| 8986 | RPS6KA4 | 4677 | NP_003933.1 | in vitro;in vivo;yeast 2-hybrid | 979 267 710 806 207 |
| 9261 | MAPKAPK2 | 11882 | NP_116584.2 | in vitro;in vivo;yeast 2-hybrid | 884 678 475 929 799 000 000 |
| 9972 | NUP153 | 4899 | NP_005115.2 | in vitro | 17255949 |
| 10891 | PPARGC1A | 5155 | NP_037393.1 | in vitro;in vivo | 11741533 |
| 23770 | FKBP8 | 5327 | NP_036313.3 | yeast 2-hybrid | 16169070 |
| 29904 | EEF2K | 7369 | NP_037434.1 | in vitro | 12171600 |
| 64145 | ZFYVE20 | 15732 | NP_071735.2 | in vitro;in vivo | 16138080 |
| 122953 | JDP2 | 16360 | NP_001128521.1 | in vitro;in vivo | 1 222 528 911 602 240 |
| 389692 | MAFA | 14346 | NP_963883.2 | in vitro;in vivo | 11416124 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Adrenergic signaling in cardiomyocytes | hsa04261 |
| AGE-RAGE signaling pathway in diabetic complications | hsa04933 |
| Amyotrophic lateral sclerosis (ALS) | hsa05014 |
| Chagas disease (American trypanosomiasis) | hsa05142 |
| Dopaminergic synapse | hsa04728 |
| Epithelial cell signaling in Helicobacter pylori infection | hsa05120 |
| Epstein-Barr virus infection | hsa05169 |
| Fc epsilon RI signaling pathway | hsa04664 |
| FoxO signaling pathway | hsa04068 |
| GnRH signaling pathway | hsa04912 |
| Hepatitis C | hsa05160 |
| Inflammatory mediator regulation of TRP channels | hsa04750 |
| Influenza A | hsa05164 |
| Leishmaniasis | hsa05140 |
| Leukocyte transendothelial migration | hsa04670 |
| MAPK signaling pathway | hsa04010 |
| Neurotrophin signaling pathway | hsa04722 |
| NOD-like receptor signaling pathway | hsa04621 |
| Osteoclast differentiation | hsa04380 |
| Pertussis | hsa05133 |
| Platelet activation | hsa04611 |
| Progesterone-mediated oocyte maturation | hsa04914 |
| Prolactin signaling pathway | hsa04917 |
| Proteoglycans in cancer | hsa05205 |
| Rap1 signaling pathway | hsa04015 |
| Retrograde endocannabinoid signaling | hsa04723 |
| RIG-I-like receptor signaling pathway | hsa04622 |
| Salmonella infection | hsa05132 |
| Shigellosis | hsa05131 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| Sphingolipid signaling pathway | hsa04071 |
| T cell receptor signaling pathway | hsa04660 |
| TNF signaling pathway | hsa04668 |
| Toll-like receptor signaling pathway | hsa04620 |
| Toxoplasmosis | hsa05145 |
| Tuberculosis | hsa05152 |
| VEGF signaling pathway | hsa04370 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd07877 | 6-350 | STKc_p38alpha |
| cl21453 | 6-350 | PKc_like superfamily |
| cd07851 | 8-350 | STKc_p38 |
| cd07878 | 8-350 | STKc_p38beta |
| cd07880 | 8-350 | STKc_p38gamma |
| cd07834 | 23-344 | STKc_MAPK |
| cd07879 | 8-350 | STKc_p38delta |
| cd07849 | 19-347 | STKc_ERK1_2_like |
| cd07858 | 19-350 | STKc_TEY_MAPK |
| cd07856 | 16-344 | STKc_Sty1_Hog1 |
| cd07855 | 19-344 | STKc_ERK5 |
| cd07850 | 23-345 | STKc_JNK |
| cd07857 | 23-345 | STKc_MPK1 |
| cd07852 | 22-345 | STKc_MAPK15-like |
| cd07876 | 2-346 | STKc_JNK2 |
| cd07859 | 23-350 | STKc_TDY_MAPK |
| cd07875 | 2-348 | STKc_JNK1 |
| cd07874 | 8-347 | STKc_JNK3 |
| cd05118 | 24-308 | STKc_CMGC |
| cd07853 | 29-343 | STKc_NLK |
| cd07829 | 24-308 | STKc_CDK_like |
| cd07854 | 23-344 | STKc_MAPK4_6 |
| cd07840 | 24-308 | STKc_CDK9_like |
| cd07841 | 23-309 | STKc_CDK7 |
| cd07830 | 24-308 | STKc_MAK_like |
| cd14137 | 19-310 | STKc_GSK3 |
| cd07838 | 24-308 | STKc_CDK4_6_like |
| cd07833 | 22-308 | STKc_CDKL |
| cd07832 | 23-308 | STKc_CCRK |
| cd07835 | 24-308 | STKc_CDK1_CdkB_like |
| cd07866 | 22-308 | STKc_BUR1 |
| cd07860 | 24-308 | STKc_CDK2_3 |
| cd07831 | 24-308 | STKc_MOK |
| cd07845 | 24-318 | STKc_CDK10 |
| cd07843 | 22-308 | STKc_CDC2L1 |
| cd07847 | 22-308 | STKc_CDKL1_4 |
| cd07836 | 24-308 | STKc_Pho85 |
| cd07844 | 24-308 | STKc_PCTAIRE_like |
| cd14132 | 5-308 | STKc_CK2_alpha |
| cd05117 | 23-305 | STKc_CAMK |
| cd07839 | 23-308 | STKc_CDK5 |
| cd07846 | 22-308 | STKc_CDKL2_3 |
| cd07842 | 23-308 | STKc_CDK8_like |
| cd07871 | 22-308 | STKc_PCTAIRE3 |
| cd07861 | 24-308 | STKc_CDK1_euk |
| cd07873 | 22-308 | STKc_PCTAIRE1 |
| cd14133 | 24-308 | PKc_DYRK_like |
| cd07865 | 23-308 | STKc_CDK9 |
| cd07837 | 22-308 | STKc_CdkB_plant |
| cd07864 | 22-307 | STKc_CDK12 |
| cd07872 | 22-308 | STKc_PCTAIRE2 |
| cd05122 | 24-308 | PKc_STE |
| cd14210 | 23-308 | PKc_DYRK |
| cd07863 | 23-308 | STKc_CDK4 |
| cd00180 | 31-305 | PKc |
| cd07870 | 24-308 | STKc_PFTAIRE2 |
| cd14134 | 22-308 | PKc_CLK |
| cd14014 | 23-306 | STKc_PknB_like |
| cd07848 | 23-308 | STKc_CDKL5 |
| cd14003 | 23-305 | STKc_AMPK-like |
| cd06606 | 30-305 | STKc_MAPKKK |
| cd07862 | 22-308 | STKc_CDK6 |
| cd14135 | 23-308 | STKc_PRP4 |
| cd14007 | 29-305 | STKc_Aurora |
| cd14099 | 22-308 | STKc_PLK |
| cd07869 | 22-309 | STKc_PFTAIRE1 |
| cd14084 | 19-307 | STKc_Chk2 |
| cd14224 | 23-307 | PKc_DYRK2_3 |
| cd14225 | 23-308 | PKc_DYRK4 |
| cd14098 | 23-305 | STKc_Rad53_Cds1 |
| cd14009 | 30-265 | STKc_ATG1_ULK_like |
| cd14226 | 22-308 | PKc_DYRK1 |
| cd14211 | 24-307 | STKc_HIPK |
| cd13999 | 30-225 | STKc_MAP3K-like |
| cd06614 | 24-309 | STKc_PAK |
| cd14008 | 31-308 | STKc_LKB1_CaMKK |
| cd14229 | 24-307 | STKc_HIPK3 |
| cd06623 | 25-305 | PKc_MAPKK_plant_like |
| cd05123 | 30-308 | STKc_AGC |
| cd08215 | 23-308 | STKc_Nek |
| cd14136 | 23-308 | STKc_SRPK |
| cd14019 | 30-308 | STKc_Cdc7 |
| cd14069 | 30-308 | STKc_Chk1 |
| cd14002 | 22-237 | STKc_STK36 |
| cd06627 | 30-219 | STKc_Cdc7_like |
| cd14081 | 31-308 | STKc_BRSK1_2 |
| cd14228 | 24-312 | STKc_HIPK1 |
| cd07868 | 30-308 | STKc_CDK8 |
| cd06628 | 30-307 | STKc_Byr2_like |
| cd07867 | 30-308 | STKc_CDC2L6 |
| cd14212 | 24-308 | PKc_YAK1 |
| cd14162 | 30-267 | STKc_TSSK4-like |
| cd14091 | 24-312 | STKc_RSK_C |
| cd14086 | 22-310 | STKc_CaMKII |
| cd05581 | 29-308 | STKc_PDK1 |
| cd14079 | 31-308 | STKc_AMPK_alpha |
| cd14227 | 24-312 | STKc_HIPK2 |
| cd14213 | 22-308 | PKc_CLK1_4 |
| cd06612 | 30-215 | STKc_MST1_2 |
| cd06629 | 30-307 | STKc_Bck1_like |
| cd14093 | 22-308 | STKc_PhKG |
| cd14083 | 20-305 | STKc_CaMKI |
| cd05578 | 24-225 | STKc_Yank1 |
| cd14119 | 31-308 | STKc_LKB1 |
| cd00192 | 29-225 | PTKc |
| cd14663 | 23-305 | STKc_SnRK3 |
| cd14167 | 20-309 | STKc_CaMKI_alpha |
| cd06605 | 25-311 | PKc_MAPKK |
| cd14097 | 24-262 | STKc_STK33 |
| cd14121 | 31-307 | STKc_ULK3 |
| cd14080 | 30-308 | STKc_TSSK-like |
| cd06632 | 23-307 | STKc_MEKK1_plant |
| cd14096 | 22-305 | STKc_RCK1-like |
| cd05611 | 27-309 | STKc_Rim15_like |
| cd14120 | 30-223 | STKc_ULK1_2-like |
| cd08217 | 24-308 | STKc_Nek2 |
| cd14202 | 30-274 | STKc_ULK1 |
| cd14095 | 71-305 | STKc_DCKL |
| cd14106 | 29-308 | STKc_DRAK |
| cd14006 | 31-305 | STKc_MLCK-like |
| cd14105 | 20-307 | STKc_DAPK |
| cd14166 | 30-309 | STKc_CaMKI_gamma |
| cd14176 | 11-307 | STKc_RSK2_C |
| cd14092 | 28-322 | STKc_MSK_C |
| cd05572 | 30-262 | STKc_cGK |
| cd13996 | 23-303 | STKc_EIF2AK |
| cd14196 | 19-307 | STKc_DAPK2 |
| cd14103 | 30-305 | STKc_MLCK |
| cd05580 | 30-219 | STKc_PKA_like |
| cd06626 | 23-307 | STKc_MEKK4 |
| cd14087 | 23-307 | STKc_PSKH1 |
| cd13994 | 30-303 | STKc_HAL4_like |
| cd14214 | 22-308 | PKc_CLK3 |
| cd14175 | 30-310 | STKc_RSK1_C |
| cd13983 | 30-308 | STKc_WNK |
| cd08529 | 24-239 | STKc_FA2-like |
| cd14185 | 71-307 | STKc_DCKL3 |
| cd14194 | 20-307 | STKc_DAPK1 |
| cd14078 | 22-305 | STKc_MELK |
| cd13993 | 23-224 | STKc_Pat1_like |
| cd06648 | 21-309 | STKc_PAK_II |
| cd14090 | 29-305 | STKc_Mnk |
| cd14046 | 23-216 | STKc_EIF2AK4_GCN2_rpt2 |
| cd06620 | 27-316 | PKc_Byr1_like |
| cd08225 | 23-234 | STKc_Nek5 |
| cd05579 | 32-219 | STKc_MAST_like |
| cd14073 | 23-228 | STKc_NUAK |
| cd08219 | 23-223 | STKc_Nek3 |
| cd14004 | 24-308 | STKc_PASK |
| cd14116 | 29-262 | STKc_Aurora-A |
| cd14010 | 67-307 | STKc_ULK4 |
| cd06630 | 30-238 | STKc_MEKK1 |
| cd06647 | 22-308 | STKc_PAK_I |
| cd14169 | 31-307 | STKc_CaMKI_beta |
| cd06610 | 24-308 | STKc_OSR1_SPAK |
| cd06624 | 31-223 | STKc_ASK |
| cd14177 | 22-318 | STKc_RSK4_C |
| cd14039 | 30-219 | STKc_IKK_alpha |
| cd06631 | 31-307 | STKc_YSK4 |
| cd13990 | 23-278 | STKc_TLK |
| cd08218 | 23-223 | STKc_Nek1 |
| cd06609 | 22-219 | STKc_MST3_like |
| cd14052 | 23-305 | PTKc_Wee1_fungi |
| cd14201 | 24-274 | STKc_ULK2 |
| cd14179 | 28-297 | STKc_MSK1_C |
| cd08530 | 23-306 | STKc_CNK2-like |
| cd14131 | 23-307 | PKc_Mps1 |
| cd14189 | 30-247 | STKc_PLK3 |
| cd14161 | 23-228 | STKc_NUAK2 |
| cd13989 | 31-219 | STKc_IKK |
| cd14082 | 30-305 | STKc_PKD |
| cd06659 | 25-315 | STKc_PAK6 |
| cd14195 | 20-307 | STKc_DAPK3 |
| cd14181 | 22-308 | STKc_PhKG2 |
| cd06611 | 16-313 | STKc_SLK_like |
| cd14215 | 22-308 | PKc_CLK2 |
| cd05595 | 30-236 | STKc_PKB_beta |
| cd14145 | 30-227 | STKc_MLK1 |
| cd14038 | 30-224 | STKc_IKK_beta |
| cd05571 | 31-309 | STKc_PKB |
| cd06613 | 24-217 | STKc_MAP4K3_like |
| cd14183 | 20-307 | STKc_DCKL1 |
| cd14193 | 30-307 | STKc_MLCK4 |
| cd06625 | 30-308 | STKc_MEKK3_like |
| cd14182 | 68-311 | STKc_PhKG1 |
| cd14118 | 47-305 | STKc_CAMKK |
| cd14184 | 22-307 | STKc_DCKL2 |
| cd14186 | 22-264 | STKc_PLK4 |
| cd14070 | 30-223 | STKc_HUNK |
| cd05573 | 22-309 | STKc_ROCK_NDR_like |
| cd14173 | 30-307 | STKc_Mnk2 |
| cd06655 | 16-308 | STKc_PAK2 |
| cd14047 | 24-217 | STKc_EIF2AK2_PKR |
| cd14114 | 22-308 | STKc_Twitchin_like |
| cd08224 | 23-225 | STKc_Nek6_7 |
| cd06917 | 24-235 | STKc_NAK1_like |
| cd06615 | 22-316 | PKc_MEK |
| cd06654 | 22-308 | STKc_PAK1 |
| cd13997 | 23-305 | PKc_Wee1_like |
| cd14168 | 15-309 | STKc_CaMKI_delta |
| cd14178 | 24-307 | STKc_RSK3_C |
| cd06656 | 22-308 | STKc_PAK3 |
| cd06652 | 30-290 | STKc_MEKK2 |
| cd14085 | 28-307 | STKc_CaMKIV |
| cd14188 | 22-227 | STKc_PLK2 |
| cd14209 | 22-229 | STKc_PKA |
| cd14199 | 23-223 | STKc_CaMKK2 |
| cd06608 | 21-223 | STKc_myosinIII_N_like |
| cd05148 | 18-237 | PTKc_Srm_Brk |
| cd14216 | 23-308 | STKc_SRPK1 |
| cd14187 | 55-308 | STKc_PLK1 |
| cd06653 | 21-262 | STKc_MEKK3_like_u1 |
| cd06621 | 27-224 | PKc_Pek1_like |
| cd06607 | 22-215 | STKc_TAO |
| cd14076 | 24-307 | STKc_Kin4 |
| cd05053 | 18-225 | PTKc_FGFR |
| cd05577 | 30-264 | STKc_GRK |
| cd08223 | 23-307 | STKc_Nek4 |
| cd14000 | 31-236 | STKc_LRRK |
| cd06657 | 21-314 | STKc_PAK4 |
| cd05072 | 18-245 | PTKc_Lyn |
| cd14058 | 30-230 | STKc_TAK1 |
| cd14071 | 30-308 | STKc_SIK |
| cd14190 | 30-308 | STKc_MLCK2 |
| cd08528 | 24-266 | STKc_Nek10 |
| cd14089 | 31-224 | STKc_MAPKAPK |
| cd14072 | 23-237 | STKc_MARK |
| cd13982 | 47-308 | STKc_IRE1 |
| cd14198 | 30-308 | STKc_DRAK2 |
| cd06658 | 21-219 | STKc_PAK5 |
| cd05593 | 24-351 | STKc_PKB_gamma |
| cd14050 | 24-218 | PKc_Myt1 |
| cd05612 | 24-297 | STKc_PRKX_like |
| cd06635 | 19-291 | STKc_TAO1 |
| cd05582 | 67-237 | STKc_RSK_N |
| cd14192 | 30-308 | STKc_MLCK3 |
| cd06633 | 21-216 | STKc_TAO3 |
| cd08222 | 23-280 | STKc_Nek11 |
| cd14165 | 30-234 | STKc_TSSK1_2-like |
| cd14048 | 30-306 | STKc_EIF2AK3_PERK |
| cd14077 | 24-305 | STKc_Kin1_2 |
| cd14146 | 30-227 | STKc_MLK4 |
| cd14061 | 30-227 | STKc_MLK |
| cd14066 | 30-220 | STKc_IRAK |
| cd14074 | 30-307 | STKc_SNRK |
| cd14059 | 30-227 | STKc_MAP3K12_13 |
| cd13985 | 23-223 | STKc_GAK_like |
| cd14164 | 24-226 | STKc_TSSK6-like |
| cd06649 | 22-227 | PKc_MEK2 |
| cd05604 | 27-331 | STKc_SGK3 |
| cd05592 | 107-232 | STKc_nPKC_theta_like |
| cd14174 | 30-307 | STKc_Mnk1 |
| cd06650 | 24-227 | PKc_MEK1 |
| cd05073 | 15-225 | PTKc_Hck |
| cd14107 | 24-308 | STKc_obscurin_rpt1 |
| cd05570 | 31-227 | STKc_PKC |
| cd14180 | 28-225 | STKc_MSK2_C |
| cd14200 | 23-236 | STKc_CaMKK1 |
| cd05630 | 30-265 | STKc_GRK6 |
| cd05067 | 18-225 | PTKc_Lck_Blk |
| cd06643 | 21-307 | STKc_SLK |
| cd05068 | 18-225 | PTKc_Frk_like |
| cd05038 | 20-218 | PTKc_Jak_rpt2 |
| cd06651 | 30-262 | STKc_MEKK3 |
| cd14163 | 24-227 | STKc_TSSK3-like |
| cd06644 | 10-303 | STKc_STK10 |
| cd08221 | 24-303 | STKc_Nek9 |
| cd14075 | 30-266 | STKc_NIM1 |
| cd05605 | 31-223 | STKc_GRK4_like |
| cd06636 | 30-261 | STKc_MAP4K4_6_N |
| cd14117 | 29-238 | STKc_Aurora-B_like |
| cd14148 | 30-219 | STKc_MLK2 |
| cd05099 | 18-235 | PTKc_FGFR4 |
| cd14041 | 22-223 | STKc_TLK2 |
| cd14665 | 23-307 | STKc_SnRK2-3 |
| cd05584 | 27-250 | STKc_p70S6K |
| cd14108 | 30-308 | STKc_SPEG_rpt1 |
| cd14147 | 30-227 | STKc_MLK3 |
| cd14094 | 70-307 | STKc_CASK |
| cd06637 | 30-261 | STKc_TNIK |
| cd14197 | 120-262 | STKc_DRAK1 |
| cd08228 | 30-234 | STKc_Nek6 |
| cd13978 | 30-229 | STKc_RIP |
| cd05594 | 24-236 | STKc_PKB_alpha |
| cd06634 | 21-267 | STKc_TAO2 |
| cd05619 | 30-227 | STKc_nPKC_theta |
| cd08220 | 23-306 | STKc_Nek8 |
| cd06617 | 25-312 | PKc_MKK3_6 |
| cd05034 | 31-225 | PTKc_Src_like |
| cd14040 | 22-223 | STKc_TLK1 |
| cd05614 | 24-308 | STKc_MSK2_N |
| cd05607 | 30-223 | STKc_GRK7 |
| cd14113 | 24-265 | STKc_Trio_C |
| cd05602 | 21-329 | STKc_SGK1 |
| cd06641 | 22-307 | STKc_MST3 |
| cd05600 | 24-225 | STKc_Sid2p_like |
| cd13979 | 21-225 | STKc_Mos |
| cd05586 | 30-262 | STKc_Sck1_like |
| cd05583 | 104-308 | STKc_MSK_N |
| cd14068 | 31-219 | STKc_LRRK2 |
| cd14111 | 22-227 | STKc_SPEG_rpt2 |
| cd05098 | 18-235 | PTKc_FGFR1 |
| cd05059 | 30-225 | PTKc_Tec_like |
| cd14049 | 23-217 | STKc_EIF2AK1_HRI |
| cd05603 | 30-227 | STKc_SGK2 |
| cd13987 | 30-224 | STKc_SBK1 |
| cd05632 | 30-225 | STKc_GRK5 |
| cd14005 | 23-308 | STKc_PIM |
| cd14205 | 27-218 | PTKc_Jak2_rpt2 |
| cd05071 | 15-225 | PTKc_Src |
| cd05069 | 13-237 | PTKc_Yes |
| cd14191 | 15-262 | STKc_MLCK1 |
| cd05041 | 30-225 | PTKc_Fes_like |
| cd14088 | 22-307 | STKc_CaMK_like |
| cd05599 | 30-219 | STKc_NDR_like |
| cd05052 | 30-227 | PTKc_Abl |
| cd05044 | 30-243 | PTKc_c-ros |
| cd05608 | 30-312 | STKc_GRK1 |
| cd14203 | 30-237 | PTKc_Src_Fyn_like |
| cd05613 | 24-297 | STKc_MSK1_N |
| cd14001 | 51-218 | PKc_TOPK |
| cd14104 | 30-310 | STKc_Titin |
| cd05101 | 18-235 | PTKc_FGFR2 |
| cd14218 | 23-308 | STKc_SRPK3 |
| cd14221 | 30-217 | STKc_LIMK1 |
| cd06646 | 24-216 | STKc_MAP4K5 |
| cd06638 | 18-307 | STKc_myosinIIIA_N |
| cd05085 | 30-225 | PTKc_Fer |
| cd05070 | 15-237 | PTKc_Fyn |
| cd05587 | 110-227 | STKc_cPKC |
| cd05620 | 129-344 | STKc_nPKC_delta |
| cd14062 | 30-240 | STKc_Raf |
| cd13988 | 30-223 | STKc_TBK1 |
| cd06639 | 18-219 | STKc_myosinIIIB_N |
| cd05039 | 18-224 | PTKc_Csk_like |
| cd05079 | 30-218 | PTKc_Jak1_rpt2 |
| cd13995 | 24-219 | STKc_MAP3K8 |
| cd05055 | 18-225 | PTKc_PDGFR |
| cd14662 | 23-307 | STKc_SnRK2 |
| cd05621 | 21-223 | STKc_ROCK2 |
| cd14154 | 30-220 | STKc_LIMK |
| cd05100 | 18-235 | PTKc_FGFR3 |
| cd05590 | 30-237 | STKc_nPKC_eta |
| cd14171 | 30-305 | STKc_MAPKAPK5 |
| cd14102 | 24-249 | STKc_PIM3 |
| cd05081 | 22-218 | PTKc_Jak3_rpt2 |
| cd14033 | 30-308 | STKc_WNK4 |
| cd05574 | 27-309 | STKc_phototropin_like |
| cd14109 | 31-308 | PK_Unc-89_rpt1 |
| cd05074 | 30-228 | PTKc_Tyro3 |
| cd06618 | 12-329 | PKc_MKK7 |
| cd05631 | 30-223 | STKc_GRK4 |
| cd05083 | 30-224 | PTKc_Chk |
| cd14100 | 24-237 | STKc_PIM1 |
| cd14060 | 31-225 | STKc_MLTK |
| cd14151 | 18-240 | STKc_B-Raf |
| cd06642 | 21-219 | STKc_STK25 |
| cd05058 | 30-237 | PTKc_Met_Ron |
| cd14036 | 30-213 | STKc_GAK |
| cd14172 | 20-262 | STKc_MAPKAPK3 |
| cd05054 | 18-225 | PTKc_VEGFR |
| cd13991 | 30-219 | STKc_NIK |
| cd05596 | 9-223 | STKc_ROCK |
| cd05618 | 30-326 | STKc_aPKC_iota |
| cd06640 | 22-227 | STKc_MST4 |
| cd05114 | 30-237 | PTKc_Tec_Rlk |
| cd14031 | 30-310 | STKc_WNK3 |
| cd05033 | 30-218 | PTKc_EphR |
| cd05606 | 123-234 | STKc_beta_ARK |
| cd05616 | 103-232 | STKc_cPKC_beta |
| cd05063 | 30-218 | PTKc_EphR_A2 |
| cd05609 | 24-225 | STKc_MAST |
| cd14150 | 27-252 | STKc_A-Raf |
| cd08216 | 36-310 | PK_STRAD |
| cd05084 | 30-215 | PTKc_Fes |
| cd05598 | 27-262 | STKc_LATS |
| cd05575 | 30-264 | STKc_SGK |
| cd05622 | 22-223 | STKc_ROCK1 |
| cd06645 | 22-216 | STKc_MAP4K3 |
| cd05065 | 30-218 | PTKc_EphR_B |
| cd14115 | 30-307 | STKc_Kalirin_C |
| cd05075 | 30-228 | PTKc_Axl |
| cd14016 | 23-181 | STKc_CK1 |
| cd14112 | 22-225 | STKc_Unc-89_rpt2 |
| cd05113 | 71-218 | PTKc_Btk_Bmx |
| cd06619 | 134-224 | PKc_MKK5 |
| cd14065 | 30-222 | PKc_LIMK_like |
| cd05057 | 19-237 | PTKc_EGFR_like |
| cd06616 | 25-321 | PKc_MKK4 |
| cd14664 | 30-245 | STK_BAK1_like |
| cd05617 | 30-223 | STKc_aPKC_zeta |
| cd06622 | 27-315 | PKc_PBS2_like |
| cd05060 | 30-218 | PTKc_Syk_like |
| cd08229 | 30-225 | STKc_Nek7 |
| cd05112 | 21-221 | PTKc_Itk |
| cd05626 | 24-310 | STKc_LATS2 |
| cd05624 | 22-223 | STKc_MRCK_beta |
| cd05066 | 30-218 | PTKc_EphR_A |
| cd13998 | 30-216 | STKc_TGFbR-like |
| cd14223 | 103-264 | STKc_GRK2 |
| cd14158 | 30-219 | STKc_IRAK4 |
| cd05589 | 27-227 | STKc_PKN |
| cd05032 | 18-236 | PTKc_InsR_like |
| cd14067 | 132-238 | STKc_LRRK1 |
| cd05035 | 30-225 | PTKc_TAM |
| cd14017 | 23-271 | STKc_TTBK |
| cd14170 | 30-223 | STKc_MAPKAPK2 |
| cd05045 | 30-225 | PTKc_RET |
| cd05080 | 30-218 | PTKc_Tyk2_rpt2 |
| cd05082 | 30-224 | PTKc_Csk |
| cd05585 | 128-310 | STKc_YPK1_like |
| cd05108 | 24-218 | PTKc_EGFR |
| cd05092 | 30-218 | PTKc_TrkA |
| cd14032 | 30-218 | STKc_WNK2_like |
| cd05116 | 30-215 | PTKc_Syk |
| cd05588 | 80-231 | STKc_aPKC |
| cd13974 | 104-307 | STKc_SHIK |
| cd05633 | 103-264 | STKc_GRK3 |
| cd05615 | 103-236 | STKc_cPKC_alpha |
| cd05046 | 24-218 | PTK_CCK4 |
| cd05103 | 18-231 | PTKc_VEGFR2 |
| cd05625 | 24-324 | STKc_LATS1 |
| cd14056 | 28-217 | STKc_TGFbR_I |
| cd14042 | 44-218 | PK_GC-A_B |
| cd14027 | 32-232 | STKc_RIP1 |
| cd13986 | 23-305 | STKc_16 |
| cd14020 | 17-309 | STKc_KIS |
| cd14064 | 30-223 | PKc_TNNI3K |
| cd14053 | 50-218 | STKc_ACVR2 |
| cd14101 | 30-223 | STKc_PIM2 |
| cd14149 | 27-244 | STKc_C-Raf |
| cd14037 | 32-217 | STKc_NAK_like |
| cd05049 | 30-218 | PTKc_Trk |
| cd05591 | 103-236 | STKc_nPKC_epsilon |
| cd05047 | 30-218 | PTKc_Tie |
| cd13977 | 23-218 | STKc_PDIK1L |
| cd14207 | 132-238 | PTKc_VEGFR1 |
| cd14011 | 121-308 | PK_SCY1_like |
| cd14110 | 70-210 | STKc_obscurin_rpt2 |
| cd05628 | 22-223 | STKc_NDR1 |
| cd14217 | 23-308 | STKc_SRPK2 |
| cd05623 | 22-223 | STKc_MRCK_alpha |
| cd05105 | 132-225 | PTKc_PDGFR_alpha |
| cd05040 | 31-218 | PTKc_Ack_like |
| cd14222 | 30-217 | STKc_LIMK2 |
| cd13992 | 30-224 | PK_GC |
| cd05093 | 30-218 | PTKc_TrkB |
| cd05048 | 27-218 | PTKc_Ror |
| cd05610 | 22-175 | STKc_MASTL |
| cd05629 | 22-219 | STKc_NDR_like_fungal |
| cd14155 | 70-217 | PKc_TESK |
| cd05107 | 124-224 | PTKc_PDGFR_beta |
| cd05051 | 50-218 | PTKc_DDR |
| cd14030 | 30-218 | STKc_WNK1 |
| cd14220 | 30-216 | STKc_BMPR1a |
| cd05601 | 122-225 | STKc_CRIK |
| cd05102 | 18-225 | PTKc_VEGFR3 |
| cd08226 | 19-310 | PK_STRAD_beta |
| cd14063 | 133-241 | PK_KSR |
| cd05109 | 30-218 | PTKc_HER2 |
| cd14141 | 50-216 | STKc_ACVR2a |
| cd05089 | 30-218 | PTKc_Tie1 |
| cd05627 | 24-223 | STKc_NDR2 |
| cd14144 | 30-226 | STKc_BMPR1 |
| cd05094 | 30-218 | PTKc_TrkC |
| cd05090 | 50-218 | PTKc_Ror1 |
| cd05095 | 70-218 | PTKc_DDR2 |
| cd14129 | 23-220 | STKc_TTBK2 |
| cd05097 | 50-218 | PTKc_DDR_like |
| cd14206 | 27-217 | PTKc_Aatyk3 |
| cd05061 | 18-218 | PTKc_InsR |
| cd05050 | 30-218 | PTKc_Musk |
| cd14156 | 45-217 | PKc_LIMK_like_unk |
| cd14055 | 50-218 | STKc_TGFbR2_like |
| cd14012 | 70-307 | PK_eIF2AK_GCN2_rpt1 |
| cd14022 | 111-308 | PK_TRB2 |
| cd14138 | 24-159 | PTKc_Wee1a |
| TIGR03724 | 63-177 | arch_bud32 |
| COG3642 | 66-178 | Bud32 |
| smart00220 | 24-308 | S_TKc |
| pfam00069 | 24-308 | Pkinase |
| PTZ00024 | 22-319 | PTZ00024 |
| PLN00009 | 22-308 | PLN00009 |
| COG0515 | 24-345 | SPS1 |
| PTZ00036 | 30-314 | PTZ00036 |
| smart00219 | 31-230 | TyrKc |
| smart00221 | 31-235 | STYKc |
| pfam07714 | 31-235 | Pkinase_Tyr |
| PTZ00284 | 22-322 | PTZ00284 |
| PHA03212 | 33-319 | PHA03212 |
| PTZ00263 | 30-223 | PTZ00263 |
| PLN00034 | 30-224 | PLN00034 |
| PHA03209 | 68-310 | PHA03209 |
| PTZ00266 | 24-232 | PTZ00266 |
| PTZ00426 | 22-219 | PTZ00426 |
| PTZ00267 | 71-236 | PTZ00267 |
| PHA03207 | 20-308 | PHA03207 |
| PHA03210 | 19-309 | PHA03210 |
| PRK13184 | 22-224 | pknD |
| PTZ00283 | 22-227 | PTZ00283 |
| PHA03390 | 14-298 | pk1 |
| PHA03211 | 68-215 | PHA03211 |
| TIGR03903 | 46-225 | TOMM_kin_cyc |
| COG0661 | 119-188 | AarF |
Ontology Information
| HPRD ID | 3774 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.