Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CSRP1 | 1465 | Cysteine and glycine-rich protein 1 | 1 | CRP; CRP1; CSRP; CYRP; D1S181E |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 19187582 | 2008 | Cell line : - Source : Cancer Tissue Bank at the First People Hospital. affiliated to Shanghai Jiaotong University of China. Sample Type : - No. of Sample : 83 Stage : TNM Stage I-IV | loss of heterozygosity (LOH) mapping, PCR, PCR products were eletrophoresed on an ABI 377 DNA seque | Down-regulation | - | By database searching, CSRP1 was hypothesized to be a colorectal cancer related tumor suppressor gene.
|
| 20089989 | 2010 | Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and Normal tissue No. of Sample : - Stage : - | Biochemical isolation to nano-LC-MS/MS analysis. | Unknown | - | This genes are differenitially expressed between colorectal adenoma and Colorectal cancer tissue. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010] |
| Chromosome | 1 |
| Location | 1q32 |
| Start | 201483530 |
| End | 201507259 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 23730 |
| OMIM ID | 123876 |
| HGNC ID | HGNC:2469 |
| Unigene ID | Hs.108080 |
| Ensembl ID | ENSG00000159176 |
| PharmGKB ID | PA26967 |
mRNA Information
| mRNA ID | NM_001193570.1 |
|---|---|
| Exon | join(1..190,10956..11068,16916..17084,18276..18387, 21884..21977,22471..23730) | mRNA Sequence | Download Select all |
| Length | 1952 |
CDS Information
| Location | join(10957..11068,16916..17084,18276..18387,21884..21977, 22471..22547) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS1413.1 |
Protein Information
| Protein ID | NP_001180499.1 |
|---|---|
| Protein Name | Cysteine and glycine-rich protein 1 |
| Molecular Wt. (Da) | 19911 |
| Protein Sequence | Download Select all |
| Length | 187 |
| Uniprot ID | P84077 |
| Ensembl Protein ID | ENSP00000272102 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 192;- |
| K | Acetylation | 112 |
| K | Acetylation | 131 |
| K | Acetylation | 108 |
| T | Phosphorylation | 79 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 87 | ACTN1 | 20 | NP_001123476.1 | in vitro | 10926853 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd09479 | Aug-63 | LIM1_CRP1 |
| cl02475 | Aug-63 | LIM superfamily |
| cd09403 | 119-172 | LIM2_CRP |
| cl02475 | 119-172 | LIM superfamily |
| cd09402 | Oct-62 | LIM1_CRP |
| cd09326 | 119-171 | LIM_CRP_like |
| cd09840 | 119-172 | LIM2_CRP2 |
| cd09480 | Sep-63 | LIM1_CRP2 |
| cd09482 | 119-172 | LIM2_CRP3 |
| cd09481 | Sep-62 | LIM1_CRP3 |
| cd09326 | Oct-62 | LIM_CRP_like |
| cd09401 | 119-171 | LIM_TLP_like |
| cd09404 | 118-171 | LIM1_MLP84B_like |
| pfam00412 | 119-175 | LIM |
| cd09358 | Oct-59 | LIM_Mical_like |
| cd09404 | Sep-62 | LIM1_MLP84B_like |
| smart00132 | 118-170 | LIM |
| pfam00412 | Oct-66 | LIM |
| cd09480 | 118-171 | LIM1_CRP2 |
| cd09401 | Oct-62 | LIM_TLP_like |
| cd09479 | 117-171 | LIM1_CRP1 |
| cd09358 | 119-168 | LIM_Mical_like |
| cd09482 | Oct-62 | LIM2_CRP3 |
| cd09481 | 118-171 | LIM1_CRP3 |
| cd09402 | 119-171 | LIM1_CRP |
| cd09476 | 119-171 | LIM1_TLP |
| cd09403 | Oct-62 | LIM2_CRP |
| cd09478 | 119-167 | LIM_CRIP |
| cd09477 | 119-167 | LIM2_TLP |
| cd08368 | 119-171 | LIM |
| cd09443 | 119-169 | LIM_Ltd-1 |
| smart00132 | Sep-61 | LIM |
| cd09445 | 119-168 | LIM_Mical_like_2 |
| cd09840 | Oct-63 | LIM2_CRP2 |
| cd09440 | Sep-59 | LIM1_SF3 |
| cd08368 | Oct-62 | LIM |
| cd09445 | Oct-59 | LIM_Mical_like_2 |
| cd09440 | 117-175 | LIM1_SF3 |
| cd09441 | 119-178 | LIM2_SF3 |
| cd09441 | Oct-70 | LIM2_SF3 |
| cd09442 | 119-168 | LIM_Eplin_like |
| cd09345 | 119-171 | LIM2_FHL |
| cd09349 | 110-171 | LIM1_Zyxin |
| cd09485 | 119-168 | LIM_Eplin_alpha_beta |
| cd09447 | 119-171 | LIM_LASP |
| cd09364 | 119-171 | LIM1_LIMK |
| cd09476 | Oct-62 | LIM1_TLP |
| cd09400 | 117-174 | LIM_like_1 |
| cd09442 | Oct-62 | LIM_Eplin_like |
| cd09462 | 119-171 | LIM1_LIMK1 |
| cd09340 | 119-167 | LIM1_Testin_like |
| cd09359 | 119-171 | LIM_LASP_like |
| cd09443 | Oct-60 | LIM_Ltd-1 |
| cd09447 | Oct-62 | LIM_LASP |
| cd09446 | 119-168 | LIM_N_RAP |
| cd09478 | Oct-62 | LIM_CRIP |
| cd09354 | Oct-69 | LIM2_LPP |
| cd09485 | Oct-59 | LIM_Eplin_alpha_beta |
| cd09359 | Oct-62 | LIM_LASP_like |
| cd09343 | 137-171 | LIM1_FHL |
| cd09414 | 119-171 | LIM1_LIMPETin |
| cd09477 | Oct-62 | LIM2_TLP |
| cd09446 | Oct-59 | LIM_N_RAP |
| cd09344 | 136-170 | LIM1_FHL1 |
| cd09424 | 21-66 | LIM2_FHL1 |
| cd09486 | Oct-59 | LIM_Eplin_like_1 |
| cd09353 | Oct-69 | LIM2_Zyxin |
| cd09331 | 119-171 | LIM1_PINCH |
| cd09421 | 119-171 | LIM3_LIMPETin |
| cd09396 | 119-171 | LIM_DA1 |
| cd09348 | Aug-64 | LIM4_FHL1 |
| cd09426 | 119-173 | LIM2_FHL2 |
| cd09406 | 119-171 | LIM1_Leupaxin |
| cd09366 | 138-171 | LIM1_Isl |
| cd09354 | 119-178 | LIM2_LPP |
| cd09439 | Oct-44 | LIM_Mical |
| cd09394 | 119-170 | LIM1_Rga |
| cd09453 | 119-171 | LIM1_ENH |
| cd09361 | 132-171 | LIM1_Enigma_like |
| cd09424 | 136-175 | LIM2_FHL1 |
| cd09486 | 119-168 | LIM_Eplin_like_1 |
| cd09457 | 119-171 | LIM2_ENH |
| cd09377 | 115-168 | LIM2_Lhx2_Lhx9 |
| cd09355 | 136-167 | LIM2_Ajuba_like |
| cd09328 | Jul-61 | LIM2_abLIM |
| cd09336 | 119-171 | LIM1_Paxillin_like |
| cd09348 | 136-173 | LIM4_FHL1 |
| cd09396 | Oct-62 | LIM_DA1 |
| cd09426 | Oct-65 | LIM2_FHL2 |
| cd09345 | 26-62 | LIM2_FHL |
| cd09454 | 132-171 | LIM1_ZASP_Cypher |
| cd09425 | 136-171 | LIM4_LIMPETin |
| cd09373 | 136-171 | LIM1_AWH |
| cd09329 | 119-171 | LIM3_abLIM |
| cd09341 | 118-171 | LIM2_Testin_like |
| cd09369 | 135-171 | LIM1_Lhx2_Lhx9 |
| cd09430 | 119-171 | LIM5_LIMPETin |
| cd09405 | 119-171 | LIM1_Paxillin |
| cd09422 | 116-175 | LIM1_FHL2 |
| cd09439 | 119-168 | LIM_Mical |
| cd09355 | 24-62 | LIM2_Ajuba_like |
| cd09423 | 116-171 | LIM1_FHL3 |
| cd09463 | 119-171 | LIM1_LIMK2 |
| cd09362 | 119-171 | LIM2_Enigma_like |
| cd09427 | Sep-62 | LIM2_FHL3 |
| cd09327 | 135-168 | LIM1_abLIM |
| cd09418 | 118-171 | LIM2_Prickle |
| cd09428 | 136-171 | LIM2_FHL5 |
| cd09469 | 119-171 | LIM1_Lhx2 |
| cd09427 | 116-171 | LIM2_FHL3 |
| COG2191 | 145-176 | FwdE |
Ontology Information
| HPRD ID | 54 |
|---|---|
| Molecular Class | Adapter molecule |
| Molecular Function | GTPase activity (GO:0003924) |
| Biological Process | Signal transduction (GO:0007165); Endosome transport (GO:0016197) |
Drug Information
No matching records could be found.