Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CYP24A1 | 1591 | cytochrome P450 family 24 subfamily A member 1 | 20 | CP24; HCAI; CYP24; P450-CC24 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26238339 | 2015 | Cell line : HT29 Source : - Sample Type : - No. of Sample : - Stage : - | Immunofluorescence, realtime RT-PCR | Polymorhpism | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Cytochrome P450 family 24 |
| Description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Chromosome | 20 |
| Location | 20q13 |
| Start | 52769985 |
| End | 52790516 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 20532 |
| OMIM ID | 126065 |
| HGNC ID | HGNC:2602 |
| Unigene ID | - |
| Ensembl ID | ENSG00000019186 |
| PharmGKB ID | - |
Protein Information
| Protein ID | |
|---|---|
| Protein Name | cytochrome P450 family 24 subfamily A member 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 0 |
| Uniprot ID | P48736 |
| Ensembl Protein ID | ENSP00000352121 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Metabolic pathways | hsa01100 |
| MicroRNAs in cancer | hsa05206 |
| Steroid biosynthesis | hsa00100 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00067 | 59-512 | p450 |
| cl12078 | 59-512 | p450 superfamily |
| PTZ00404 | 58-505 | PTZ00404 |
| COG2124 | 89-511 | CypX |
| PLN03112 | 59-476 | PLN03112 |
| PLN00110 | 59-510 | PLN00110 |
| PLN02394 | 59-485 | PLN02394 |
| PLN03234 | 59-484 | PLN03234 |
| PLN02687 | 59-509 | PLN02687 |
| PLN02183 | 59-480 | PLN02183 |
| PLN03195 | 60-514 | PLN03195 |
| PLN02966 | 59-474 | PLN02966 |
| PLN02655 | 56-464 | PLN02655 |
| PLN02936 | 323-501 | PLN02936 |
| PLN02426 | 325-490 | PLN02426 |
| PLN02169 | 320-498 | PLN02169 |
| PLN03018 | 257-484 | PLN03018 |
| PLN00168 | 311-494 | PLN00168 |
| PLN02971 | 59-498 | PLN02971 |
| PLN02302 | 326-489 | PLN02302 |
| PLN02196 | 325-514 | PLN02196 |
| PLN02290 | 326-509 | PLN02290 |
| TIGR04538 | 297-476 | P450_cycloAA_1 |
| PLN02500 | 277-491 | PLN02500 |
| PLN02987 | 311-483 | PLN02987 |
| PLN02774 | 310-483 | PLN02774 |
| PLN03141 | 370-509 | PLN03141 |
| PLN02648 | 338-393 | PLN02648 |
| PLN02738 | 86-514 | PLN02738 |
Ontology Information
| HPRD ID | 4404 |
|---|---|
| Molecular Class | Not Available |
| Molecular Function | Kinase regulator activity (GO:0019207) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
| Uniprot ID | DrugBank ID | Name | Type |
|---|---|---|---|
| Q07973 | DB00136 | Calcitriol | SmallMoleculeDrug |
| Q07973 | DB00146 | Calcidiol | SmallMoleculeDrug |
| Q07973 | DB00153 | Ergocalciferol | SmallMoleculeDrug |
| Q07973 | DB00910 | Paricalcitol | SmallMoleculeDrug |
| Q07973 | DB01285 | Corticotropin | BiotechDrug |
| Q07973 | DB02300 | Calcipotriol | SmallMoleculeDrug |