Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
CD55 1604 CD55 molecule, decay accelerating factor for complement (Cromer blood group)  1CR, TC, CROM 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24978917   2014Cell line : -

Source : -

Sample Type : CRC tumor and adjacent normal tissues

No. of Sample : -

Stage : -

ImmunohistochemistryUp-regulation-CD46, CD55, and CD59 are up-regulated in colon cancer


Gene Details



NC_000001.10 (207494817..207534311)

View Larger Image
   
Gene Type protein coding
Gene Family CD molecules, "Blood group antigens"
Description This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]  
Chromosome 1
Location 1q32
Start 207494817  
End 207534311  
Strand +  
Gene Sequence

   Download   Select all

Length 39495  
OMIM ID 125240   
HGNC ID HGNC:2665   
Unigene ID Hs.126517   
Ensembl ID ENSG00000196352   
PharmGKB ID PA27137   

mRNA Information


mRNA ID NM_001114752.2
Exon join(1..394,911..1096,3088..3279,4151..4250,5281..5366, 9637..9825,15222..15347,15858..15938,17926..17946, 18920..19037,38075..39495)  
mRNA Sequence

   Download   Select all

Length 2914  



CDS Information


   
Location 295..1617
CDS Sequence

   Download   Select all

CCDS ID CCDS31006.1



Protein Information


      
Protein IDNP_001108224.1
Protein NameCD55 molecule, decay accelerating factor for complement (Cromer blood group)
Molecular Wt. (Da)45142
Protein Sequence

   Download   Select all

Length 440  
Uniprot IDQ9Y237
Ensembl Protein ID ENSP00000362773  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SGlycosyl phosphatidyl inositol GPI353
SPhosphorylation140
NGlycosylation95

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
1378CR1398NP_000642.3in vitro11694537   


Pathway Information


                  
Pathway Name Pathway ID
Complement and coagulation cascades hsa04610
Hematopoietic cell lineage hsa04640
Viral myocarditis hsa05416


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd00033225-284  CCP
cl00043225-284  CCP superfamily
cd00033163-221  CCP
cl00043163-221  CCP superfamily
cd0003398-159  CCP
cl0004398-159  CCP superfamily
cd0003336-94  CCP
cl0004336-94  CCP superfamily
smart00032225-283  CCP
pfam00084225-283  Sushi
smart00032163-220  CCP
pfam0008498-158  Sushi
pfam00084163-220  Sushi
smart00032115-158  CCP
smart0003236-94  CCP
pfam0008436-94  Sushi
PHA0292798-280  PHA02927
PHA02639159-284  PHA02639
PHA02639119-283  PHA02639
PHA02831125-294  PHA02831
PHA02817157-283  PHA02817
PHA02817220-284  PHA02817
PHA0295497-271  PHA02954


Ontology Information


   
HPRD ID3328
Molecular ClassComplement protein
Molecular FunctionTranscription factor activity (GO:0003700)
Biological ProcessOrganogenesis (GO:0009887)  



SNP Information


View SNP Geneview Report   

Drug Information


Uniprot ID DrugBank ID Name Type
P08174DB00446ChloramphenicolSmallMoleculeDrug

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO