Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| DNAJB8 | 165721 | DnaJ (Hsp40) homolog, subfamily B, member 8 | 3 | MGC33884, CT156 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24450541 | 2014 | Cell line : SW480, HT29, HCT15 Source : Kind gifts from Dr K. Imai (Sapporo, Japan). Sample Type : - No. of Sample : - Stage : - | - | Up-regulation | - | DNAJB8 is expressed and has role in CRC CSC/CIC and that DNAJB8 is a novel target of CRC CSC/CIC-targeting immunotherapy. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Heat shock proteins / DNAJ (HSP40) |
| Description | The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma. [provided by RefSeq, Jun 2012] |
| Chromosome | 3 |
| Location | 3q21.3 |
| Start | 128181275 |
| End | 128186091 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 4817 |
| OMIM ID | 611337 |
| HGNC ID | HGNC:23699 |
| Unigene ID | Hs.518241 |
| Ensembl ID | ENSG00000179407 |
| PharmGKB ID | PA134881798 |
Protein Information
| Protein ID | NP_699161.1 |
|---|---|
| Protein Name | DnaJ (Hsp40) homolog, subfamily B, member 8 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 232 |
| Uniprot ID | Q8N4U5 |
| Ensembl Protein ID | ENSP00000299045 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd06257 | Mar-58 | DnaJ |
| cl02542 | Mar-58 | DnaJ superfamily |
| pfam00226 | Mar-66 | DnaJ |
| smart00271 | Mar-61 | DnaJ |
| PTZ00100 | May-56 | PTZ00100 |
| COG0484 | 3-106 | DnaJ |
| PRK10767 | 1-106 | PRK10767 |
| TIGR02349 | 4-106 | DnaJ_bact |
| PRK14290 | 3-106 | PRK14290 |
| PRK14297 | 1-106 | PRK14297 |
| PRK14280 | 3-106 | PRK14280 |
| PRK14284 | 2-105 | PRK14284 |
| PRK14301 | 3-105 | PRK14301 |
| PRK14282 | 3-121 | PRK14282 |
| PRK14281 | 3-113 | PRK14281 |
| PRK14294 | 4-105 | PRK14294 |
| PRK14298 | 3-106 | PRK14298 |
| PRK14276 | 1-106 | PRK14276 |
| PRK14278 | 1-106 | PRK14278 |
| PRK14291 | 3-113 | PRK14291 |
| PRK14292 | 1-107 | PRK14292 |
| PRK14277 | 3-106 | PRK14277 |
| PRK14289 | 3-111 | PRK14289 |
| PRK14286 | 4-106 | PRK14286 |
| PRK14295 | Mar-93 | PRK14295 |
| PRK14285 | 3-106 | PRK14285 |
| PRK14293 | 1-106 | PRK14293 |
| PRK14279 | 3-107 | PRK14279 |
| PRK14283 | 3-112 | PRK14283 |
| COG2214 | 3-146 | CbpA |
| PRK14299 | 3-106 | PRK14299 |
| PRK14300 | 3-106 | PRK14300 |
| PTZ00037 | 4-106 | PTZ00037 |
| PRK14287 | 3-106 | PRK14287 |
| PRK14288 | 3-100 | PRK14288 |
| PRK10266 | 3-105 | PRK10266 |
| TIGR03835 | 3-104 | termin_org_DnaJ |
| PRK14296 | 3-105 | PRK14296 |
| COG5407 | May-69 | SEC63 |
| PTZ00341 | Apr-71 | PTZ00341 |
| PRK09430 | May-34 | djlA |
| COG5269 | Feb-66 | ZUO1 |
| PRK01356 | Jan-65 | hscB |
| COG1076 | May-54 | DjlA |
| PHA03102 | Aug-62 | PHA03102 |
| PHA02624 | Aug-62 | PHA02624 |
Ontology Information
| HPRD ID | 17555 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.