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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ARID3A | 1820 | AT rich interactive domain 3A (BRIGHT-like) | 19 | BRIGHT |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24366420 | 2014 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 690 Stage : - | Tissue microarray and immunohistochemistry | Up-regulation | - | Strong expression of ARID3A may predict a good prognosis in patients with CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008] |
| Chromosome | 19 |
| Location | 19p13.3 |
| Start | 925733 |
| End | 972816 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 47084 |
| OMIM ID | 603265 |
| HGNC ID | HGNC:3031 |
| Unigene ID | Hs.501296 |
| Ensembl ID | - |
| PharmGKB ID | PA27485 |
mRNA Information
| mRNA ID | NM_005224.2 |
|---|---|
| Exon | join(1..23,3226..3860,6382..6706,34056..34128, 38212..38395,38797..39044,40536..40832,42369..42467, 45842..46780) | mRNA Sequence | Download Select all |
| Length | 2823 |
Protein Information
| Protein ID | NP_005215.1 |
|---|---|
| Protein Name | AT rich interactive domain 3A (BRIGHT-like) |
| Molecular Wt. (Da) | 62758 |
| Protein Sequence | Download Select all |
| Length | 593 |
| Uniprot ID | P53350 |
| Ensembl Protein ID | ENSP00000300093 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 81 |
| S | Phosphorylation | 88 |
| S | Phosphorylation | 77;- |
| S | Phosphorylation | 101 |
| S | Phosphorylation | 119 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 695 | BTK | 2248 | NP_000052.1 | in vitro | 15203319 |
| 1832 | DSP | 513 | NP_004406.2 | in vivo | 9780002 |
| 1869 | E2F1 | 1806 | NP_005216.1 | in vitro;in vivo | 9780002 |
| 1870 | E2F2 | 2692 | NP_004082.1 | in vitro;in vivo | 15017387 |
| 1874 | E2F4 | 2806 | NP_001941.2 | in vitro;in vivo | 15017387 |
| 5371 | PML | 23 | NP_150241.2 | in vitro;in vivo | 15017387 |
| 6672 | SP100 | 6844 | NP_001073860.1 | in vitro;in vivo;yeast 2-hybrid | 15017387 |
| 7157 | TP53 | 1859 | NP_000537.3 | in vitro;in vivo | 1 213 666 215 017 380 |
| 10477 | UBE2E3 | 5000 | NP_006348.1 | in vitro;in vivo;yeast 2-hybrid | 15017387 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam01388 | 238-326 | ARID |
| cl02633 | 238-326 | ARID superfamily |
| smart00501 | 239-331 | BRIGHT |
| smart01014 | 239-326 | ARID |
Ontology Information
| HPRD ID | 5410 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Ion channel activity (GO:0005216) |
| Biological Process | Transport (GO:0006810) |
Drug Information
No matching records could be found.