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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
HBEGF 1839 heparin-binding EGF-like growth factor  5DTR; DTS; DTSF; HEGFL 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22930170   2012Cell line : KM 12C, KM 12SM, HT 30

Source : ATCC

Sample Type : -

No. of Sample : -

Stage : -

Microarray analysis,Real time RT-PCR and Flow cytometryUp-regulation-Gene differentially expressed and analysed bye by Microarray.

KM12C, KM12SM (SM), HT-29 cell line were used for this study.


Gene Details



Chromosome: 5; NC_000005.9 (139712428..139726188, complement)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 5
Location 5q23
Start 140332843  
End 140346603  
Strand -  
Gene Sequence

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Length 13761  
OMIM ID 126150   
HGNC ID HGNC:3059   
Unigene ID Hs.799   
Ensembl ID ENSG00000113070   
PharmGKB ID -   

mRNA Information


mRNA ID NM_001945.2
Exon join(1..321,520..693,3792..3969,10577..10732,11856..11946, 12324..13761)  
mRNA Sequence

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Length 2381  



CDS Information


   
Locationjoin(276..321,520..693,3792..3969,10577..10732, 11856..11928)
CDS Sequence

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CCDS ID CCDS4223.1



Protein Information


      
Protein IDNP_001936.1
Protein Nameheparin-binding EGF-like growth factor
Molecular Wt. (Da)21072
Protein Sequence

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Length 208  
Uniprot IDO14514
Ensembl Protein ID ENSP00000313046  



Post-translational Modification Information (Source : HPRD)


Residue Type site
TGlycosylation75
TGlycosylation85

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
960CD44115NP_000601.3in vivo7532176   


Pathway Information


                                    
Pathway Name Pathway ID
Bladder cancer hsa05219
Epithelial cell signaling in Helicobacter pylori infection hsa05120
ErbB signaling pathway hsa04012
Estrogen signaling pathway hsa04915
GnRH signaling pathway hsa04912
Proteoglycans in cancer hsa05205


Structure Information


No matching records could be found.

Domain Information




ID Location Description
PHA02887108-148  PHA02887
cl20100108-148  PHA02887 superfamily


Ontology Information


   
HPRD ID4062
Molecular ClassGrowth factor
Molecular FunctionProtein binding (GO:0005515)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO