Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ARID2 | 196528 | AT rich interactive domain 2 (ARID, RFX-like) | 12 | KIAA1557, DKFZp686G052, FLJ30619, BAF200 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24382590 | 2014 | Cell line : - Source : Hospital District of Helsinki and Uusimaa, Finland. Sample Type : CRC tumor No. of Sample : 46 CRC tumor Stage : - | Exome capture and sequencing | Mutation | - | ARID1A mutated in 39% of the tumors (18/46), also ARID1B (13%, 6/46), ARID2 (13%, 6/46) and ARID4A (20%, 9/46) were frequently mutated. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 [PubMed 15985610]).[supplied by OMIM, Mar 2008] |
| Chromosome | 12 |
| Location | 12q13.11 |
| Start | 46123494 |
| End | 46301820 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 178327 |
| OMIM ID | 609539 |
| HGNC ID | HGNC:18037 |
| Unigene ID | Hs.317304 |
| Ensembl ID | ENSG00000189079 |
| PharmGKB ID | PA134916396 |
Protein Information
| Protein ID | NP_689854.2 |
|---|---|
| Protein Name | AT rich interactive domain 2 (ARID, RFX-like) |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1835 |
| Uniprot ID | P25391 |
| Ensembl Protein ID | ENSP00000374309 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 1496 |
| S | Phosphorylation | 631 |
| S | Phosphorylation | 635 |
| T | Phosphorylation | 653 |
| S | Phosphorylation | 689 |
| T | Phosphorylation | 692 |
| T | Phosphorylation | 1723 |
| S | Phosphorylation | 32 |
| S | Phosphorylation | 626 |
| S | Phosphorylation | 1292 |
| S | Phosphorylation | 1808 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 6597 | SMARCA4 | 4459 | NP_001122321.1 | in vivo | 15985610 |
| 6605 | SMARCE1 | 4382 | NP_003070.3 | in vivo | 15985610 |
| 8900 | CCNA1 | 4946 | NP_003905.1 | in vitro;in vivo;yeast 2-hybrid | 15159402 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart01014 | 14-101 | ARID |
| cl02633 | 14-101 | ARID superfamily |
| smart00501 | 14-106 | BRIGHT |
| pfam01388 | 17-101 | ARID |
| pfam02257 | 522-603 | RFX_DNA_binding |
| cl03504 | 522-603 | RFX_DNA_binding superfamily |
| pfam09770 | 575-852 | PAT1 |
| pfam09606 | 630-1019 | Med15 |
| PHA03247 | 626-1097 | PHA03247 |
| pfam05109 | 698-1020 | Herpes_BLLF1 |
| pfam09606 | 656-1162 | Med15 |
| pfam09606 | 793-1235 | Med15 |
| pfam09770 | 984-1162 | PAT1 |
| pfam03153 | 685-850 | TFIIA |
| pfam07223 | 738-966 | DUF1421 |
Ontology Information
| HPRD ID | 1033 |
|---|---|
| Molecular Class | DNA binding protein |
| Molecular Function | Extracellular matrix structural constituent (GO:0005201) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.