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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
CADM4 199731 cell adhesion molecule 4  19TSLL2, Necl-4, SynCAM4 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22718847   2012Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 513

Stage : -

Tissue microarrays by immunohistochemistryMutation-Loss of CADM4 expression is relatively frequent in colorectal adenocarcinomas and may play an important role in cancer progression and patient survival.


Gene Details



NC_000019.9 (44126519..44143991, complement)

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Gene Type protein coding
Gene Family Immunoglobulin superfamily / V-set domain containing, "Immunoglobulin superfamily / C2-set domain containing", "Immunoglobulin superfamily / Immunoglobulin-like domain containing"
Description -  
Chromosome 19
Location 19q13.32
Start 44126519  
End 44143991  
Strand -  
Gene Sequence

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Length 17473  
OMIM ID 609744   
HGNC ID HGNC:30825   
Unigene ID Hs.370984   
Ensembl ID -   
PharmGKB ID PA162380931   

mRNA Information


mRNA ID ?NM_145296.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS12627.1



Protein Information


      
Protein IDNP_660339.1
Protein Namecell adhesion molecule 4
Molecular Wt. (Da)0
Protein Sequence

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Length 388  
Uniprot IDQ6WRI0
Ensembl Protein ID ENSP00000282466  



Post-translational Modification Information (Source : HPRD)


Residue Type site
NGlycosylation67
NGlycosylation262
SPhosphorylation361

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd05885140-220  Ig2_Necl-4
cl11960140-220  Ig superfamily
cd05761140-220  Ig2_Necl-1-4_like
cd0588129-120  Ig1_Necl-2
cl1196029-120  Ig superfamily
cd0571729-120  Ig1_Necl-1-3_like
cd0770129-120  Ig1_Necl-3
cd0588229-120  Ig1_Necl-1
cd05884141-220  Ig2_Necl-3
cd05883140-222  Ig2_Necl-2
pfam13927224-295  Ig_3
cl11960224-295  Ig superfamily
cd05759143-220  Ig2_KIRREL3-like
cd07705143-206  Ig2_Necl-1
pfam13895230-298  Ig_2
pfam08205127-210  C2-set_2
cd05729226-308  Ig2_FGFR_like
cd00096241-302  Ig
cd05856238-304  Ig2_FGFRL1-like
cd05728238-298  Ig4_Contactin-2-like
cd04968238-298  Ig3_Contactin_like
cd05731241-308  Ig3_L1-CAM_like
cd05851238-305  Ig3_Contactin-1
cd04978238-308  Ig4_L1-NrCAM_like
cd00096141-211  Ig
cd05725242-308  Ig3_Robo
cd05737233-298  Ig_Myomesin_like_C
cd05891235-298  Ig_M-protein_C
cd05857227-308  Ig2_FGFR
cd05743238-316  Ig_Perlecan_D2_like
pfam13927120-203  Ig_3
cd05740235-308  Ig_CEACAM_D4
cd05876241-308  Ig3_L1-CAM
cd05730224-309  Ig3_NCAM-1_like
cd05749243-298  Ig2_Tyro3_like
cd05732237-307  Ig5_NCAM-1_like
pfam00047238-293  ig
cd05754235-295  Ig3_Perlecan_like
cd05867238-298  Ig4_L1-CAM_like
cd05755137-212  Ig2_ICAM-1_like
pfam0768626-120  V-set
smart00294344-362  4.1m
cl02555344-362  4.1m superfamily
cd05723241-308  Ig4_Neogenin
cd07693224-301  Ig1_Robo
pfam07686229-295  V-set
pfam13895127-217  Ig_2
cd05742238-295  Ig1_VEGFR_like
cd05869231-307  Ig5_NCAM-1
smart0040640-105  IGv
cd05745237-308  Ig3_Peroxidasin
cd05893243-298  Ig_Palladin_C
cd04972233-302  Ig_TrkABC_d4
cd05870237-305  Ig5_NCAM-2
cd05735243-311  Ig8_DSCAM
cd05760241-300  Ig2_PTK7
cd05746243-306  Ig4_Peroxidasin
cd05861238-308  Ig1_PDGFR-alphabeta
cd05736243-310  Ig2_Follistatin_like
cd04969238-308  Ig5_Contactin_like
COG2887108-271  COG2887
cl00641108-271  Cas4_I-A_I-B_I-C_I-D_II-B superfamily
pfam0004737-106  ig
cd05852238-308  Ig5_Contactin-1
cd00098227-290  IgC
cd0009932-107  IgV
smart00408237-298  IGc2
smart0041030-120  IG_like
smart00408137-205  IGc2
smart00410231-308  IG_like
smart00409231-308  IG
pfam07679224-298  I-set
smart0040930-120  IG
PHA03273100-340  PHA03273
smart00410135-203  IG_like
smart00409135-203  IG
pfam02124251-341  Marek_A
pfam0767926-120  I-set


Ontology Information


   
HPRD ID13732
Molecular ClassUnclassified
Molecular FunctionAntigen binding (GO:0003823)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO