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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
EMP1 2012 epithelial membrane protein 1  12TMP, CL-20 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24744589   2014Cell line : SW 480

Source : -

Sample Type : CRC tumor and adjacent normal tissues

No. of Sample : 63

Stage : TNM stage I-IV

Immunohistochemistry, Western blot analysisDown-regulation-Low EMP1 expression in colorectal cancer is associated with increased disease severity, suggesting that EMP1 may be a negative regulator of colorectal cancer.


Gene Details



NC_000012.11 (13349602..13369708)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 12
Location 12p12.3
Start 13349602  
End 13369708  
Strand +  
Gene Sequence

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Length 20107  
OMIM ID 602333   
HGNC ID HGNC:3333   
Unigene ID Hs.719042   
Ensembl ID -   
PharmGKB ID PA27770   

mRNA Information


mRNA ID NM_001423.2
Exon join(1..205,14802..14921,16812..16908,17014..17154, 17867..20107)  
mRNA Sequence

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Length 2804  



CDS Information


   
Location 248..721
CDS Sequence

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CCDS ID CCDS8660.1



Protein Information


      
Protein IDNP_001414.1
Protein Nameepithelial membrane protein 1
Molecular Wt. (Da)17432
Protein Sequence

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Length 157  
Uniprot IDQ08209
Ensembl Protein ID ENSP00000320580  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam008221-151  PMP22_Claudin
cl215981-151  Claudin_2 superfamily


Ontology Information


   
HPRD ID2735
Molecular ClassCell cycle control protein
Molecular FunctionProtein serine/threonine kinase activity (GO:0004674)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO