CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
12115344	2002	Cell line : HT 29, CaCo 2 Source : - Sample Type : - No. of Sample : - Stage : -	Immunohistochemistry, western blotting.	Hyper Activation	-	Activation of Akt plays an important role during the progression of colorectal carcinomas by helping promote cell growth and rescue cells from apoptosis.
25714871	2015	Cell line : DLD 1, Colo205 Source : Yamagata University Hospital. Sample Type : CRC Tumor No. of Sample : 65 Stage : -	Immunohistochemical analysis	Mutation	-	AKT1 E17K mutations contribute to primary resistance to cetuximab.
20133737	2010	Cell line : SW480, SW948, HCT116 Source : - Sample Type : - No. of Sample : - Stage : -	Colony-Formation Assays,Apoptosis Assays, Western Blotting	Mutation	-	Nockout of AKT1 and AKT2 simultaneously makedely inhibites the proliferation and reduced metastasis in these two cell lines.
11756242	2002	Cell line : HepG2, HCT 116 Source : - Sample Type : - No. of Sample : - Stage : -	Immunohistochemistry	Up-regulation	-	Overexpression of this proto-oncogene as an early event during colon carcinogenesis.
15888491	2005	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	Real time RT-PCR,Immunoblotting, Immunohistochemistry and Transfection	Up-regulation	-	-
24297510	2014	Cell line : HepG2, HCT 116 Source : - Sample Type : - No. of Sample : - Stage : -	Plasmid construction and transfection, MTT assay,real timeRT-PCR,Colony formation assay ,Wound scratch assay.	Up-regulation	-	Akt1 involves in tumor cell migration and invasion.

Gene Details

NC_000014.8 (105235686..105262080, complement)
View Larger Image   

Gene Type	protein coding
Gene Family	Pleckstrin homology (PH) domain containing
Description	The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
Chromosome	14
Location	14q32.33
Start	105235686
End	105262080
Strand	-
Gene Sequence	>gi|568815584:c104795743-104769349 Homo sapiens chromosome 14, GRCh38.p2 Primary Assembly CGGCAGGACCGAGCGCGGCAGGCGGCTGGCCCAGCGCACGCAGCGCGGCCCGAAGACGGGAGCAGGCGGC CGAGCACCGAGCGCTGGGCACCGGGCACCGAGCGGCGGCGGCACGCGAGGCCCGGCCCCGAGCAGCGCCC CCGCCCGCCGCGGCCTCCAGCCCGGCCCCGCCCAGCGCCGGCCCGCGGGGATGCGGAGCGGCGGGCGCCG GAGGCCGCGGCCCGGCTAGGCCCGCGCTCGCGCCCGGACGCGGCGGCCCGGTGAGTCCCCGCCCGCCGTG GCCGCCCGGGCCTGGATTTCCTCCCCGCGGGCCGGGCCGCTTTGTTCGCGGCCGGTCGGGCCGGGGCGCG AGCCGCGGCGCCGCCAGAATGGAGGAGCGGGAGCAGGAAGTGGCCGAGCGGGCCTGGGCGGGGAGGGCGC GGGGCGCGCGGGCCCGGCCAAGGGAGGGCGGCCCCACGCCGGGCGCCGGGGGTGCAGGCTGCCGGCCCCA GCCTCCCTCATGACCTTGGGGAGGCCGCTCCGCCGGGCGAGGCCGGGACCCGAGAGAAGGGACGCCGCCG GGCCTGGAGCTGGGGCTCGGGGTGCCCCTGCGGGCCGTGGGGCTCCCCGGGCGCTGGGCCAGCGAGGCAG CCGGCGGAGGTGCCCCGGGGTTGGAGAAAGACTCGCCGCGGCCGGCCTTCAAGTTTGTGGGAGGGCCCCG GAAGGAGACTTCGTTTCCCACGGACGAAAAGTTGTACGTGGTGGCGGGGTACCCAGGCTAGCCACAAAGG ACTGTGACCCTCCTGGGCCCCGGAACTGCTTCCTGTCTTGGGTGGGCCCTGGAGGTCCTGCCCGCCCATC CCAGAGGCCAAGGCTTGGAGGGCAGCTGGGGCTTGCCCCTTAGATTGAGTATCCTGGGGCGCTAGCGAGC TTGGTCCTGTCGGGACGGCCTCTGAGTGCTGCCTTGGTCAGCGGGTGAGCTTGGGCCCCTGCTCTGCAGC CAGAGGCCGCCCCACATTCACTCCTGGGTCTCTCGGCCTTGCTCCAGGTGGCCACTTCTTGACTGCTTTG AGTCCCTCATCCGAGCGAAGGGCGGACGGAGTCCGTTGGTGGGGGTCCGGTTGCCTCTCCCGGGAGCTGT GTAGACTTCTCATACACCAGGGTTCTGGAGGCAGATGGAGGAGCCCTTTCGAAAACAGAGTATTTTTTTT TAAGTTGTGACTTAATAATAGTAGCAAGAATATGTGCTTATGGTAAAGGCAGGCGGCAGGTACGGAGGCT GTGGGAAGTCGGGGTCCCTCCGCCCCCACAGGCAGCCCTGTGCTGGCCTGGTGTATACGTTTCTGTGCAG ACGTACACCACCCTGTGTGAGCACAGATGTATTTTTACACATGGCTCTGGACAGCTGTCTGACTCTGTCA GCAGCAGGCCTTGGAGGGGCTCAGGCCCGTGTGGGGGTGGGGGGACATCCAGAGGTCTTTGAGTCCAGCC CTCTGCCTCCAGGCCACGCCCACTCAGTGTCGTCAGAGCCCCCTGTGCCTGAGGCGTGCGCGGCTCGGAG CCCTGCCCTCGGAGTCCTGCGGTGCCTTCCTCGAGTCTGGCCTGCTTTCCATCCTGCTAAGTACTTGGGG CATTTCCCTCTTTGGGTAAGGTGTGGTCTTCCCTGTCCTGGCATTAGACACAAGGCAGTGGGCCTTCCTG CCATTCTAAGTGTAGCTTAAGACAATCAGTGCAAAGCAACCCTTTGTGGGTGTCCAGCCCTTGCCTCGGG AGGCCAGAAAGGTGGCCTGGGGGGAGAGCGTCTAAGCTGGCTGTGGAAAGACCCATGTTGGGATCCATTC CACAGAGGTCGTCAGGGGTCTCTGCCTGGCCTGGAGGTCCCAGAGAGGACCCTCCTCCCCTCAGGAAGGC CCATCTGGAAGGGTAGCAGAGGACTGCTCACAGGAAGAGCATGCGAAGTGCTCTTTCTGGGGATGCCTGT AGTTGGTGATGTGGGAACTGGGTTTTGAGGGATGCCTAGGAGTTCATCCATCAGAGGGGAAATGAGGAAG CCATGCAGGATCAATGGATAAAGTGTGCTCAGGTGAGGGTTGGCTGGTGGGCCGCTGCAGGGCGGGGGCC TGTCCAGTGCTCCCCCACTTACTTGCTGCCTCCCGACTGCTGTAATTATGGGTCTGTAACCACCCTGGAC TGGGTGCTCCTCACTGACGGACTTGTCTGAACCTCTCTTTGTCTCCAGCGCCCAGCACTGGGCCTGGCAA AACCTGAGACGCCCGGTACATGTTGGCCAAATGAATGAACCAGATTCAGACCGGCAGGGGCGCTGTGGTT TAGGAGGGGCCTGGGGTTTCTCCCAGGAGGTTTTTGGGCTTGCGCTGGAGGGCTCTGGACTCCCGTTTGC GCCAGTGGCCTGCATCCTGGTCCTGTCTTCCTCATGTTTGAATTTCTTTGCTTTCCTAGTCTGGGGAGCA GGGAGGAGCCCTGTGCCCTGTCCCAGGATCCATGGGTAGGAACACCATGGACAGGGAGAGCAAACGGGGC CATCTGTCACCAGGGGCTTAGGGAAGGCCGAGCCAGCCTGGGTCAAAGAAGTCAAAGGGGCTGCCTGGAG GAGGCAGCCTGTCAGCTGGTGCATCAGGTTAGGGAGGCTGGGAAGGCCTTTTGGGGATGGGGGTGATTTG TCCAACGGCTGGGGGAGGTGGGAATGGGGAGGTGAGCAAGGCAGCAGCTCTCAGGGCCTGGCTGTTGCGG GTGGTGGTGGCAGGGGCTGGAGGCTCTAAGCCTAGAATAAGGAGAGGCCCAGGTCCAGGGAACTGTGTTC AATTACATGGATTTGACACTTGGCAGCCCTGAGTGTTTTGGGGAGAGGGAAGGCAGGCGGGCAGATGGGG GTCAGAGAGCTTAGAGGGATGGCAGCCCACCTGGGAAGGCAGGTGCGGGTGGAGCCCCCAGGCACGTGCA GTGGGTCTCTGGCTCACCCAGGGCGAGGAGCTGCCCTTAGCCAGGCGTGGCCTCACATTCAGCTTCCTTT GCTTCTCCCAGAGGCTGTGGCCAGGCCAGCTGGGCTCGGGGAGCGCCAGCCTGAGAGGAGCGCGTGAGCG TCGCGGGAGCCTCGGGCACCATGAGCGACGTGGCTATTGTGAAGGAGGGTTGGCTGCACAAACGAGGTTA GTACCCGCTGCCAGGGCTGGGCCTGGGGAGGGAGAGATGGGGGTAGTAGCCCCAGGGTCTGTGAGTGCCT GTGCCCTGCTGGGTGGGAGGGGCTGCCTCCCCTGGGGCTCCTGGGCTGGCCTAGGGTGAGTGTCCTGGGC CCCATGTCTTCCCATGGCATGGAGGGCACGGCCTCGGGGAGGCCAGGAGGATGAGGCCCTGTGCAGGGCC GGCCATCTGAGTGGCTTCCTGGTGTGGGCCCTGGCAGGCGGGGGAGCTGCTGCCAGCCTCTCTCCTGGCT TTCCTGGAAGGCAGCGAGGACACTGGGCTGTTCCAGGGTCTGGCACGCTGGCGGCCCAGGGCACTGCCCA AGGGCTCCTGAGGGCAGGGCAGGGCTGCTTGGCTTGGCCTGGTGCCTGCTTCAGGCCTGAGCTTTGGGGG TGGGGGGAATCCGTACCGCCTGGGCACAGGGCATGTTTGCCTTGGAGCTGCAGAGCTGGCTGAGCCAAGT CCCCCAGCCCCTGTGTCCCCCTCCTCACTCATTTGGCCTTGCAGCCTATGGAGGAGGTGCTGCCCGAGGG GCCTGGCCAGCAGCTGGGTGGGATGGGAGCTGGGGACATAGCCCCACCCCTTCCAACCCTGTGCAGGCCC TTCTGCCTCACCCACCCTCCGTTGCTCAGCGGGGTGCGGTGGAGTCTGGGTGGCTGTTTTGCTCCTCTGT CCTGCTAGGGTGGGCTTCCTGTTCAGGTCCAGGTCCTCTGGCCAAGTCACTCTCTTCTGCCCCAGGCGGA ATCGGTCCGCCCTCTCCTGACTTCTTTTTCCAGACTTGTTCCCTCCTAAGTTCTAGTGATCTCATGCCAG CAGCCCCCCGGCTTTACGTACACCCTCTAGCAGATGGGTTTCACATCTGGTAGTGGGGAGACCCCAAACA CAGCTGGAGCAGACAGGGAGGTGTGGCAAAAGTAGGTGTCACAAGATGGGGCATTGTGGGATGTATAGGA GCTCACAGAAGAGCAGGCCTAAGGAGCCACAGGAGCCTGGGGGTGGGGTGAAGGAGTGACCGAGATGAGA TGCTGGGGGAATCAGGGGTGTGGCTGGCTGTGTGTTTGGAGTGTTTGAGTGGGCAGCTACCAGTGATGGC ACGCGGGGCCTCGAGATGAAGACAAGGAGGCTGCAGACGCCTGTGGTCCTTGGGGAGCTTCTGGCTCTGC TTCCCCCCAAGGCCTCCTGCCGCATCCTGCCTTCTCCATCCCCTCCCCGTGTGCTGTCCCCTGCTTGTTC CCCAGGAGTCCTGCCACCTGTGCCTGGAGGTCCTCTCCTCACCTCACAGCCCTCTTTGGTGTCAGGGACC CCCTGCCCCGACCCTGGCCCTGTTCCTCTCTGTGTCACATAGTCTGCTGCCTGGGGCCGCTGCTTCTTTA TCCTTGGCAAATGTGTGTTTGTTGATAGACTGTTGGATCTCGGGCTGACCCAGGAGATGCCAGGGCCTTG ACTGCCCAGGGGCCCAGGCCCCAGTTACTGGGGCACCCATCAGCCAGCTGGGCCTAGGCAGGAGTGCTCC CCCGAGGCCAGGTGATTTTCAGGCTGCTGCTGATGTCGTGCCTTCAGGAGGGGCCTGGCAGGGACAGGAC ATCAGGCCCAGTGGGGCGTCCAGAGAGCTGAGTTTGAACCCTGGTTAGCCACTCTATCGCCATGACCCTT TCCAAGAGCAAGGTCATTGAGCTCCTTGGGCCTCAGTTTCCCCATCTACACCAGGGAGCGGTGGTGGGAG AGAGACCTGGTGGAGTGGAGAATGGCTTGTGGGCGGCCCTGAGTTGGGGTCCGGCCAGCCTCAGCAGCCT CTGGGCTCTGTCATCTGGCCCCTAGCCTCAGGCCAGGAGAGAGGGTCCTGTACCTCTACCCCCGGCTCTT CCTCCTCCATCCCCAGTGTAGTGGGCGCTGAGGATGGGAGGTGGCGTGGATATGACATATGCCCTTGGCA GGCATAGCCCCTCTTGTTGCCGAGAGCAGGTGGCGTCCACCCGCATGGCCGGCCGCTCCTTGCGGAGGAA AGCCTGTCCTCCGGGGCCTGCCGCATTTCGCCACTCCCGTCCCTGGGGTCCCCTGTGTGTCTTGCAGATG TGCTGTGCCACCCTCCTGGCAGGGCCAGCCCCACCCGCAACACTGGTTAGAGGTACTAGCTGCCTTCCTG TCCCTAGCAGGGCTGTGCTGGGCTGACCCCACCCGTGCTTCACAGTGCTCAGGCCTGGCTGGGGGTGGGG AGGGAGGGAGGGACGCAGTGACTGTCCTCCAGGCCCGGCCGCAGCCCCTTGCAGACGCCCTGTTCCACTC CCCCCCAGCCTTGCTCCTGCAGGTCAGGGTGCTTGTCTCAGAGGCTGGCCCGCACCTGTCCCCTTTGCCG GGACTCCCCACGACCGTGGCCTGGGGCACTTTGGTTCTCAGCTGAATCCCCAGGTGACAGTCCCACCACG GCTACTTGGGCTGGCCACACGTGGCGTGATGGTGCCTTCAGGGGTGATGTGGTCATTGAGATGAGAGGGG ACGGGTATGCCCTGTGTGTGAGGGGTGGGGTGGCAGTGTCTGCAGGCTCCTTCTCCTGCTCCTTGGGAGG TGAGCGTCATCTCTGGGAAGTGGCCCAGGCTGCTTTCTGTTGTTCTGATGTGTGTGCTCTGAGTCAGAGG AGCTTCAGGGACAGAAGGGACCGGGCATGGGGACACAGGAGTTCCGGCTGCAGGCCTGTGTGGACCTGTG GCTGGACCCAGGCGAGGCCTCTGGGTCTGCACATCTAACAGGGAGATGGTTCCTGGAGGGTGAGCTTAGG CTGTTAAGGGCAGGAGCTAGTGAGGAGGCTGGTGGGGCCTATAGGGACAGGGGGCCAGATGTCCCCTCCT GTTTCGGCTGTCTCACTGGATAAGCAGCCCAGCTCAGCTCTGGCCATTGGTGGTCTGGTGGGCTCAGTGT TGCTCAGACGTTTGCATTTTCAAAGATTTGTTCTGTTGTGTGAAGTCTCCTGATTTTTGAAGGCTGACAA TTTTAAAAAATCAATCCTGGGCCAGGGCGCAGGTCTGGCTGAACTCGGCCTCCAGCCTGCAGTTTTCCTT CCTTTGATAGCTCCGTGCCAGGCTTTGGCCAGAGGCTGTGTGGCTCTTTTGAGGTACTTTCCCCAAACAG CTTGCTCACCTTGCCCGCTTGCCCCAGTACTCCTGGGGCCGTGCACCAGCCTGGCTGCAGCCTAGCCCCG TGGAGAGCTGCCCTGGTGCAGCCCCGGCCTGGAGCCTGTTTTTGTCCACTCGCGGCTGTCTTCCTGAGCG TCCCCCCGTCCACATGGCTGGACCAAGTGGGTCAGGAGAGGGCCGAGGCGGGTGGCCGGGATGCTGGGAC CCAGGATGAGGTGCTCTGGGCTCTCGAGAAAGGGCTGGGCCTAGGCCAGGAGTGGGTGCCGGCCGCAGGG GCACCACCTGGACTCCCTCAGGCTGGTCGCTGTCCGAGAGGGGCCGGGGAAGAGCTGCAGGCCTGGCTGC CTTCGGCAGGCTGTGACCCAGCAGGCCAAGGCCGAGTGGGCGGGGGTCGAGGGAAGCTGCCTGGGGCGCG TGGGTTACGCGGCAGACGCTCCTGAGTGTGTGGGCAGCGTGTCCAAGCCACGGATCTGGGTGCCTGGCCG GGCCCGGGTGACACGGGACCGTGTGTCCATGCGGCTCACGGAGGGTCCAGTCTCCGGACATCTGAGTCCT TGCCATGCCCTACCCCGGGCCCATGCCTGGCATAGACCCCCCAGTCCAGGCCTCAGGGCAGCCCCCTCAC CACTCCTGCTGAGTTAGCCCCAGGCGTCCCGGTGGGGAGTATGGAGGCTGGTCTCTGACCCCAAGCAGGT GCCTAGGCTGGGCCTCCTTCCCACCCCCTCTCCCCGCCTTGAAGTCCTGGCACTGGCTGTCCCTGCGGGG GGGCACTGAGGCAGGGAGAGAGTGGTTCCTACCCCAGTGTGTTACTTCGCTTTGGTGAGCGACATAGAAC CTCACTGCATCCCCAGCTGCTGCTCAGCCATCCAGCTGGTCCTGGGGTCCCTGCGTGAGGTGGGGGACCT CAGAGGGTACAGGCCACTCCCCTTCATCCTGGAGGAGGCCTTGGCTTTGCTGAGTAAACACCCTTGAGAA GAGGTCTGTGGGGGACTCTGAGCCCACTCCAGAGAGCAGCTGCTGCGGAGGGCCCCGCAGGGCTAATTGT TTGTGTGCAGATGGAGGCTGCTCATTACCCCGCCAGGATGAGGGGCCCAGCAGGACCCTGAGGGAGGGAG CCCGCAGACTCTCCCCTCAGCCTGTGGGAACCTTTGGGCTCCAGGCCAGGGCTGCCTGTGCCTCCTGGGC CTCAGTTTTTCCCAGGCTGTCAGGTGAGGGTCAACCCCAGGCTGCGTCTAGGTGGCTTCAGTGTGAGACC CGCGGGCCCTGGGCTGGTTAGTGCCAAGCTCTGCCTCCCCTGGGGGAGCGTTGAGGGTCTGGAACGGCCC CCGTGGGCAGGCCAGGGACAGAGATGGGGAGGCAAGTGTGCTGGCTCCTGGTGGGAGGGCTGGGCAGAGA GTGGGGGTCCCAACAGCCCTGGGCCTACCCGGGAGAGGGGCAGGAGGCACAGGCTGGTGGAGGTCATGGC ATGGCTGTGGTGGAGGCCGCCAGCATCAGGGAGGTTCCTGTTTTGGGAGCTTGTTGAGTTCTCACTTCAA AAACAACAAAAGAGGAAGCCGAGGTGGCCTTGAGTGGGGGTGAGGGGTCACTGCTGGCCCCAGCCCTGGA CCTTAGCCCCCACGCCTGGTGGCTCCTGAGTGGACAGCTCTTCTTCCTGTGTGTTTCTTGGTCACTGGCC CTCTCTGGGCAGGGATGCCCTGTGGGGGGCTGGACTCCGGGAAGGGAAACTGAGGCCCAGGAGAGTGGAC AGAATGTGGGTGGAATGATTCCTGTGCTGGGGCCTAGACCCCCGTACACCTTCCACTCTCAGGAGAAGCC TGGCCGGGTTGCATCAGGCCGGGTTCCTAGAAGTCCTGCACGAGGCTGAGCGGAGGGAACTGGCGCGGCC CCCGCTGGCGTCCCCTCTGCCTGGGCACACCCGGCCCGGCTTGGGGCCAGCACCCTGCCCTCGGGCCCTC CCATAGCTGAGACTGGTGGCTGTGGCTGTGGCTCTGGGCCTGCTCCCCAGGCCACCCTGGGTGGGCAGCT GCCTGCTGCTTCTGTCTGCTTGGACCATTGTGCCTAGTCCCATGGCCTCAGGAGAAGGTTCCCCCAGCCC AGCGCTGGGGCCCCGGGCAGGTTGGCAGAGGGCCCTGGGGCTCCAGGCCAGGATGGGGCTGTTAGGCGAA CCCTAGGCCCCTTACTTCCTCATCTCCAACGGGAGTTCCCTTCCCTGCCATGCCGCCTTTAGGTGTGTTT TCCTTGAACCTTAAGGAATGATAGGTTTGGATTTCAGAAACGTTGGAATTGAGGGGGTTGGGAGTTCATG GGTGACTCTGCTGCCAATGTTGCGGGCTTTGGGGTGGGATCCTTGGGGCGCTGTGTTTGGGCTCACACAC CCCCCAGGCGGGCCCGGTGACTGCAGACCCCACCCATACCCTGTAACCTGGCGGGCCCACCTGCCCAGGC CCTCAGCTGGTTGTCCAGCTCAGGGGTGGAGACACCCCCTGGGCAGGCCTGGCGGGGAGGTGGCTGCTCC CTGGGCCTGGAGAATGCAGAGAGGCCCTTCGGCTGGCCAGGGTCTGGCTGGCCTCCCCACAGACTGGGGC CAGGGGCACAGCAGCCAGGTGTAGGGCGCGGAGACGCTGAGCTGCACAAGCTTGGTGAGGTGTGGGGTGA GGCCACGGGGGTCAGGGCCACAATGTCCCAGCAGGCCGGGGGATCAGAAGGAGCACCCTCCACAGCTGGC CGTGCTCTGGGGGCCCTCCTGCCCCAGGCGTGGCTCCAAGTTGGGGCAGAAACAAGATGGTGGGGAGATG GAAGGCCCCTCTGTGGCGGGTGCTTCCCATGGTCGGTGTGGAGGACGAGGTCCCTACTGCCTGGTTCCAG TTCCCCCAGCAATGCAGGGCACTTTTCCTGGGGTGTCAGGGATTGAGAGGCCAGCACTGGAGCCCTTCAA CCGCCAGGGGCCCTGCCCAAGAGAGACGGGAGGAGGGAGGGGCTGTGGGCATGGCTGCGTGCCCCCGGCC GAGCCCCGGAAGGAGCCTGTGCCCGTGCCCACTTCCTTTCCCGAGGGCAGTGTCTACACGTGGGACACTG TGGCCAGCCCTCCCTCGCAGCAGGCACTGTGTGCTGTCCCCATGCCCAGCTTCCTCCCACGCAGGGAGCG AGGGTGAGGGCCCTGGGAACCCACTGGGTGGAGGGCACTTGGCAAAGCCTGCTGCAAGTTATGGGGAGAG TGGGCGGGGGCAGAGTAGGAGGCGCCAGGGAGGGGCTGCAGCCTCATCTGCAGGGGTCCTGAGTAGGCAG GGTGGGCCATGACATGGGTGGGGCTTGTTTGGGGCAGACCAAAAATGAGGTGGGGGACAGGGACAGGGAC AGGGTCTTGGGATGTGCTGGGCTCTGCGATGGATGGGTGTGTGGCAGGTGGGGTGCCTTTGCCGGCCCGA GGGGTGGGTGACGGGCAGTGCCTGTGGGGGAGGACATCCAGGCCCAGGTGGTCTGTCAGGGGCAGCACCA GGGAGGCCCAGTACCCCACCCAGTAGAGCCCCAGGAGAATGGAAAGCTGAGACCCAGGTGCTTCCCTGGA GTGGCAGGAAGAGAGGCCCCAGCGCCTCCGGCTGTGCCTCAGCGAGGTGGACGGGGTCATGGTGGTGCCG CCTGCCCGCACCATGTTCCTCCCGGGGTGTGTGTGTCGGGCTGAGGCCTGCTCCATGGTGGAGCGGAAGG AGGTGAAGAATTTGCAGTTTGTGTCAAGTTACAACCCCTGCCTTGGCGGCAGGACCTGGGGTCTCTCTGG TCATGATCTGCCTCTGAGGGTCACCTCCCCTAAGTCTCCGTTTTCCCAGGGAGCTGATGGGCATGATGAG CCCTGCCCGCCCTGCCTGCCTGGTGGGCTTTCTGGGAGAGCAGAATGGGTCCTGGGCTGGGCGAGGCCCA GGCAGGTGGAGCGCCAGTCCTCTGCCTGGCGGGAACAGACACCTCTCCTTGTGCAGACTGGCCACTTGTG CCCCCTCAGAAGGGCTTGTGCCGGGAGGAGCAGTGGATGTATTTCACCCACAGACCTGGGGGCTCCAGCC AAGTGGGGTCAGCTGGCCTCCGTTGTGTGGCCCCTCCCCTGCCCCCACCCCAGCCTGGTTGTTTACAGGG TTCGAGGGCTGCTGGTAAAGGGGTGTGTACTCCCGGGCCCGGGCAGAGGCCTGGCAGGCCGGGCCCTTCG CGGTGAGCTGTGCGGTCTCCTGGCAGGCGGGGAGGGTGGGTTGCGGGCCCCTCATGGGCTGCCGTCAGCG GAGCCGTCTGCTCAATGTGCTGGAGAAGGTAAATGGGCCCCCGGCAGCTGTCGGGGCGATGGATGTGTCG GCAGTGGGGACCACGGTGGCCGCTGTCAGCTGGCGCCCGCTCCCAGGGCCTGCTGGGCTCACTTTGCTGT GGAGAAGCAGCTCGGTGCCGCCTGGCACCCTGCCAGCCGCTGCCACCACCGTCTCTGCGAAGTGTTTATC CAGCAGTTTCCTGAGAACTGGGGACTTTGAGAGAATGTTCAGGGAGCTGAGGACGTGGTGGCCTAGGGGG GCTGACACACCTGGTGGCTCAGGAGGTGGTCAGTCCCGGGACGTGGAGGGCCACCAGCTGGCCCTCAGGG GCCCACCCAGTCCTGCCCATGGCGCGTGGGTCCTGGCCCCCATGTCTAAGTGGGTGCCGCTTTGGGGGGC CTGACCCACAGTGTGGCCTGGGACACGTGTGTGAGGCGTGGAGAGGGTGGGCTGCCTGTGACTGTCCATG TGGTCCCCGTGGTGGTGGTGGGGTGGGTTGGGGGAGGCCAGGCAGGAGCAGCTTCCTCTCAGAACCCCGG TATTTGGTCCAGGAGGACTTCTGGGAAGGAACCCTCTTTCCCTGGGGGTGCTCCAGCCCCTTCCTGGGGA TGAGCGGGGTTGGGGATGGAAGGTCACTCCTGCCGGAGGGCCACCCGGGACATCGGGATGCCAGAGGGAC CAGGGCTGGGGTTGTGTGGGGCCCAGGAGGTGCAGGAGGAGTCGAGGGAGCCTGGTCTCCGCTGTCCCCC CGGGCAGGGACAGGAGTCTGGCCAACTGCCTACCCCCCACCGAGGGCAGCCACCTCCCATGCCTGGAGCC CTGGGCCATGGATGTGCTGGCTGGTGGGGAGGGTTACGGGTTTCATCAGGCACAGGAGCCCCTGCCCTTG TGGCTTCACAGGACCTGGTCTTGGATAGGTGCAGTGTCACAGGGTTAAGGGTCAGGGTGGCTCCCACCTG GCCCAGGGCTGGCCTTGAGAGAACCCTGAAGGGTGGGACCGGAGCTGCTGCCTCCCACTGCCCAGGGGGC CAGCAGGAGGGTGAGACTGGAACTGCTGCTTCCCCGCTGCCGAGGGAACCGGCCATGGGGCAGGAGGGTG GGACCGGAGCTGCTGCTTCCCCCTTGCCCAGGGGACCAGCCATGGGGCAGGAAGGTGGGACCAGTCCCCA GTGCCGTCCTCCACTCGGCCCCCCACTCAGGTCTTCTGGCAGTGGTGTGGGGTCCCCCATCCGGACTTGC TGACATTTCTGAAGGGGCACCTAGCCGTCTTCCCTGCCAGACCCTGAGGCCCAGGCCGGGGTTGCACTGG GACCCTGCCTGCTCCAGGTCCCGGGTCTGAAACATGTGCAGCGGGTGGGGACTTGGGGGTTCTTGAGCCC AGCATGGGGGTGTGAGAGTTAGGGACTGAAGAGGCCCCCTGGGCCTGAATGCTGGGCGGTCTCCATTGCC CTTGGGAGTGGCTGCTGGCAGGAGATGACTCTGGCTGTGTGTGGGGTGGGGCGTGCCCTGGCCTCCCCAT TTGTTGCCTGCCTGTACCCGTCTGGAGTGAGGGCCTGGCGTGGCAACCTGGGGGTCTGTGCCCACTCTGT GTTTGGTGCCCTCAGCTGTGCAGGCAGGTGGGTGGGGTGGTGTTGGGGGGGTGACTGGGGTGGGGTGGGG GGATGCCAGCTGGCTGATGGTGGGGAGATGGAAGGCCCCTCTGTGGCGGGTGCTTCCCATGGTCGGTGTG GAGGACGAGGTCCCTACTGCCTGGTTCCAGTTCCCCCAGCAATGCAGGGCACTTTTCCTGGGGTGTCAGG GATTGAGAGGCCACTCTTCAAGTGGACTGTACTCCTGCCTCGAGTGGGGGGCATCTGAGGACCACAACAG GGTGGGGAACTCAAGTTAAGTCCTGGATGACAGGTTCCAGTTCCCCTGGGGACCCTCAGGATAGTGAAGG AGAAGACTCCATGTGGGTTGGTCTCTTTGTGTGAGGGGTCTGGGAGGGCAGCCCTGGCTGATGTGTCTGT GCTCCCACCCTCCTGAGGGACCCGGAGTAGGCAGGTGCAGGCCTGCAGGCGTCCTGTGGCCATGAGGACA GTGATGCTGGGCCCCGGGTGGCTGTCTCCTCCACCTGCCCCGTCCTGTGTCACCCCAGTCCTGGATCAGG GAGTAGTGGGGCCCTGCCGCATCTGCTGTCGGGGCTGGCCGCCCACCCAGCATCCTGTCTGGGCTGAACT CGTTAAGATGCGCGCCACGGCCCTGGCTGCAGCTGGCACCCCCCCAAGTGATCCTCTAGCTGACCCTCTA GGCGAGAGATGAAGAAAGAGAACTGTGTGTCTCTGGACCCCTTACCCCGGGTCCCTGGGGATCCTGCTCC TCCCCTGGAGGGGTCTGTGTGCTGGGCTGGGATGCCGAAGACAAAGGCCACGTGAGGCCCCTTCACTCAC ACCCGTCTCCTGGGGTAGGCCCTGATCGCCGTCTGTTCCCTGGGTCTGTGGGGCCAGGCGAGGGGAAGGC ACTGAAAGCCCAGGGCCCATTTGGGCCTCTGCCCATCCCAGGACTCCCCAGGAATGCTCGGGGCTGGGCA CCTGTCCTCTCCCACCCCCCACGCCTGGTAAGCGCCGCCCCTGGGCCTGCCCCTCCCGCACCCCCAGATC CAGCTCCCAGAACCCCCCAGATGCAGCTCACAGAACCTGGGGCTGGGCTTGTGGCAGCAGGGTCAGGGGC AAGGCTGGGGTTGGGCACGGGAGCTGCGTGCTCGGGGGCAGCACGGGGCCATGCTGGGCACGGTGGGGGC TGGCAGCAGTTGGTGGATAAGATGGGTTTCAGGGGTGCCGGGCCTGGGCGCTCATCAGTCTTCCCGCTCA GTTAGCGTCCCGGGGAGTGGCAGCTGGCAGGATGGGAGGCACTCCATCAGGGGCCGACAGCTCCAGACTG GCATGCAGGCGGGTGGGCGTGAGCAGCGGGGTGGCCCAGGATGGGGGACGGGTGGGGTGGGCTGCATGCA GCCCCCTGAGCCTGCTCTGCTCTCACTGAGCGCCCCTGCCTGCCCGCTGCACCTGCAGGGGCCCTGTGGC TGGGGGAGGGGACGTGGGAGGCGGGGTGGAGCTGCGTGGCACGTATGTGCGTGTATGTGCACACTCGGGG GTGTGCGAGATCCCAGGTCAGGGACAGGAGCCGGCACCCAAGGGTGGCAGGACCACGCCTGCTCGGCAGC CCACTGGCAGGGGCATGGAGGGCTTGCGGAGTGGGTGGGGTCTCCTGATGAGTGCTCTTGGGCACAGGGG CAGATTCTGGGCCCTGGATCATCCTCCCTGCAACTGGGTGTTGGCCGTCCTCCAGAGGTGTCAGGCAGCT ATGAGTGGGCTGTGGCTGTCCCCTTCCTGGTCCACCCCAGACCTGACAACAGCCTCTTCCCACACTCAGG CCCTGCTGGGTGGGGTGTCCCCACCCTCCACCAGCATCCCCCCAGCAGCCCTGGCTTGGGCAGAGAGAGG GCTGGTCTTGTGGAGACCACGCCCCGTGGTGCTGGTGGGAAGGGCATTGGGCAGCTGGGGCCGGGGTAGG AGGGAGAGGTCACCTGGCCGGGGGGTGGCCATGTGTCGAGCCTTGGTGGCTCACCTCTATTAAAGAACTC CCCCGTGGCTCCCTGGAAAGTAGAATGCCTGCTGGGATGCCCATGACCCATGTCCTCTGAGCTCCCCTGG GGCTGCTGCCCTGCTGGGACTTCCCTGTGCACCAGGGAGGGCTGGACGCGTCTGGGCTCACCACGAAGAC CCAGCAGGACTGGGTGGTGGGTGGTCTGGTGATGGGACAATTGCTTGTCCCCCACATCCCTCCAGGTGTC CCTGTCTGGGGCTCAGTGTGGCATGAAAACCCAGGCCCCAGAGCTCAGGGACCCCAACCCCTTACCCTGG CCCCCTCCCTAACCCCTGCCCAGTGACCCCTCAGATGAAGCAGTTGCCTAATTAGTAAGTTCCCTGTTGT TCAAACTCCTTGCTTGGCAAAATGTAAGTGGAACATTTTTTTCCGAGTGTCAGTATGAAAAATGGTACTT GCTGGGCTATCACCGAGGACAGCTGCTCTGATTCTGAAGTGTGAACGCCTGCGTACGGCTGATGCTGCAA AACTTGAGGGAGAATGTTCCCGTGTACCTGAATGACCCACGGGTGGGACGCGGCAGGGCCGACGGCGGCA GGGCCTGAGTGTGGGTCTCAGCCTGGGGACTTGGCACCCTCTGTGCCCTGGGGCCCCTGCCCAGCTGGCT GGGCCACCTCCGTGTCTGGCTTCATCGGCAGTCCCCAAGACGGTGCTCCAGGCCCCTAGACAGGGAGTGC GATCCCACGGCAGTGGGCAGTCCTGTCCCGCGAGCCCGGCCCTCAGTCTGAGTGGTGCTGACCTCTAACT GTGGACGCCATGCTCCATCCTCCTGGTGGGTGGCGGCGGGGCGGGGGGGGCGGCCATGCTGGGCAGCCCA CACAAGCCACTGTCACCTGCTGTCGCCACCTGGCCGACCCTGGTTGATTGGGGAATGCTGTCAGCCCCGC AGCCCCTGTGGCCATAGCTGGGGCCCGAGCTGCTGCTGGTGCCTGCTGGGGACTGGCTGGTTTAGGGCTG CCTCCTCCAGGAAGGCTGTGCAGACTGGCCCAGACCTCTTCCCAGCCTCCTGTCCATGGTACTCCATCCC CTGCGTCCAGCTGGCCCAGCCCGTTTTCAGACACAGCTCGGGGTGGCTCTTCTGAGAGGGGCGCTGTGGT GGGGCGAGTCTGCCTTCCCGTTGACCCAGGGCCGTTTCTGTCGCTGGCCCTAAGAAACAGCTCCCGTACC GCGCCTGCCCCCTGGGACTCAGGCATCCCAGGCACATCTGTCCTGGCACACCCAGTTCCTGCCTGGCTGC CTGGCGAGGGTCTGACGGGTAGAGTGTGCGTGGCTCTCACCACCCGCACGTCTGTAGGGGAGTACATCAA GACCTGGCGGCCACGCTACTTCCTCCTCAAGAATGATGGCACCTTCATTGGCTACAAGGAGCGGCCGCAG GATGTGGACCAACGTGAGGCTCCCCTCAACAACTTCTCTGTGGCGCGTAAGTATCCCCTTGGCCTCTCGG GATTCAGATTTGGGGGGTTGGCTGGAGCCCTCTTTGCCCACCAGGCCCCACGATGGGGGTCCCCTGGAGC CTCCAAGTCCTGGGCTGGCAAGCAACAAGCACTGGCTGGGTGGGGGTCTCTGGGCCGAGTCCCGAGGCTG GCTGGGCAGGGGTCTCCGGGCTGAGTCCCAAAGCTGAGGCTGGCTGGGTGGGAGTCTCCAGGCTGAGTCC TAAGGCCGAGGCTGGCTGGGCAGGGGTCTCTGGTCCAAGTCCCGAGGCCGAGGCTGGCTGGGCAGGGGTC TCCGAGCTGAGTCCTGAGGCTGGCTGGGCGGGGGTCTCTGGTCCGAGTCCCGAGGCCGAGGCTGGCTGGG CCGGGGTCTCTGGGCTGAGTCCCGAGGCCGAGGCCGGCTGGGCAGGGGTTTCTGGGCAGAGTCCTGAGGC CGAGGCTGGCTGGGCGGGGGTCTCTGGGCCGAGTCCCAAGGCTGGCTGACCCTGGAGCAGTTCCCTGGTG CCCATGCTCTGGAAGCTGGAGGGTCCGGACAAGTGGCAGCAGAGCCCAGTCTCAGGGTGGACAGCTGCCC CGGGGGCCCCTCCTCCAAGGGGGTTAGATAGAGCCCATCAGGGCCTCTCCTTGGGAAACCCCTTGGGTGA GGGGGCAAGAGTCCATTGGGGTCTCCAGCTCTGAAGCCTCCATCACTCGAGGAAGAGCTCGTGCCTCTCC CTGCACAGGCTCTCAGCCTCCAGACCCCATGGCAGAGCCTTTGCTTCCCCTCTGTGAGGCTGCCTCCTTG CCCATGGAGGGGCAGGTGCAGAAAGGCCAGCGGGGGACCTTGGCCGGAGCATCCCACAGAGATGAGAGAC ATGTGACGCTCCCTGCTCCGCCCTGCTGTGGCTTTATTCCTTACCTGTAGCGGGGGCAGGTGCGACCCTA CCCATGTCAGACGGGAACCCTGGCATGGAGACCCAGGCGCCCTGCTAGGTGGGAGGCTGGGGACACGTGG GCCTCCCAGCATGGTCCCCATTTTCTGTGTCCCTGTCCTGGAGCCCAGCTCTGCCTGTGGCAGCCAGAGA CACGGGTTGGGCATGCAGGTGTGACTGAGTGGCTAATTAGGGCCCAGTTGTGGGCCATCTGTATGTGGCA GGGCTGGGTAACTGCAGGCCTCTGGGATCTGTCTCAGGCAGGTCTGTGGTGCAGAGCGAGGTGCCCACCA GGGGCTGGCCTTAGGTTCCATCCCCATGTGCTGCATCGGCCCCTCCCCTCCAAGTAGCTCTGCCCTCCTT TCTTTGAGGCCTGCGGTCCTCCGACTCCCTTGAACTTGCTGGACCCCCAGGTTCTGGTCCAGGGTCTGGG AGGAGGTTAAATGCAGGGAATCCGTCCCCAGGCTGGGCAGGGAAGGACTCCCACCCTTGGTGCCTGCACG TATAAGGGGAGGTGGGGTCAGTCTGGCACCCTGGCTGCTAGGTGGTCTGTGGCCAGCAAACCGTGCCCTG AAGCTTCTAGTTGGGAGGGGCAGAGGCCTTGCCCTGCAAAGCCCCAGGCTGAGGGGCTGGGGTTGGGGTG GGGTTTACCAGGACCTGGTTCCTGTAAGCCGAGGTCTCCTTCCCTGGCTCTTCCAGCCTCAAGCCAGCAG TAGCAGGGCAGCCTGATAGAGTAGGGCACCCCAGGGGTGAGGGGAGACCAGGAAGGCAGACACCCCTGTC TCCTGACAGCCTCGTAACCATGCAGGAGACTCACTGTGACTTGTCCCACACCCTCCCCAGTGTCTCCTCG GTTGGGGCTGGGGGCTTCAGGGATCAGGGAGAGGCTGGGTGCCAGCAGCGTGCCTGGTGGCACCTGGGAC AGGGCCTTGCTGGGGGTGGGTGCTGTGGGTGTGCTCGCCAGGCCGAGGCATTGGGAAGGAACGAGGTGGG GAGCTCTCTGGAGAGGCACACGGGTGGGTACCAGCTGGAGGTGTTGCCTGAGCAGCTGGCAAGGCTGGGG CCTTCAGATTAGGCCATAGGTGAGTGGCCTGGAGCGCCTGGCCAAGGAGCAGAGCTGGGCAGGGGCCAGG GGCTGTGCTGGGCCTCTGTCCGGGGCTTTTCTCCGGGGAACGGTTCCGGGGCAGTGGGCTCGAGACTCTG GCCCTGGGGATTGCATACTGGGGCAGATCGGACCATCCAGGAGCGAGTGGGAGGTGGGTGTGCCGGGGCT TCACACCGGTTTCCACTTCTCTGGCCTGTGTTGACACAGGCCACCCTCCCCACCAGGCTGGTCCCGAGCC CCCTCCTGGCCCCCAGGCCTGGAAGACAGCTTCCTTGCTGCCTGGCCAGGCCCCCTTGTGGTTGCCAGGG CCTCGATGCTGGAATGTCAGAGGCCCCCCACTGGCCCCTCAGCCTCCTCCTGCTTTGCACAGGCTGGGCC AGAGCCTGCCACGGAGCCCCAGCGGCTACACACTCCACTCACTCACACCTCTCAGGGCCCCGCACGTTCC CACAGCCCTCAGGGTGTACGTGCTGTAGGTGTGGCTGTGCCCCAGGTATGTGTTCCCCAGGTGTGCTTGT GCCCCAGGTGTGGCTGTGCCCCAGGTGTGCGTGTGCCCCAGGTGTTCGTGTGCCCCAGATGTGGCTAGGT GTCTAGATGTGTTCTAGATGTCTGTGTATTCCAGTGTGGCTGTGTCCCAGGTGTGCGTGTGCCCCAGGTG TGTGCCTCAGGTGTGCGTGTGCCCCAGGTGTGGCTTTGCCTCCAGTGTGTGTGTGCCCCAGATGTATGTG TGCCCCAGGTGTGGCTGTGCCCCAGGTGTGCCTGTGCCCCAGGTGTGGCTGTGCCCCAGGTGTGCCTGTG CCCCAGGTGTGGGTGTGCCCCAGGTGTGGGTGTGCTCCAGGTGGCTGTATTTCCCAGGTACTCAGGGTGA GGTTGGGAAAAAAGCAGGACATTTCTACACTAGGTGGGACAAGCAGGTTTCTGGGGTGCCCCCCTCATGC CAGCCCCTCTGTGGGATCTCCATACCCCTCATCCTCTGAGGCCTGGCGCACGGCGGGGCTCAGAGACTGA AGGAAGGACTGTAGGAGTGGACGATGGTGGGGGTTTGACCTGACGCCGGGCCAGATGCCCTGTGTGGCTG CCTCAGCCTGGAGTAGAGTGTCTGAGCTGGAACAGGGGTCCTAGCCCCACTCTGTGAGGCGAGAAACTGA GGCTTGGAGAGAGGAAGAGATGGGGCTTCCCAGGACCTGGTGGGTGGTATGCAAGGGGAGCTGGCTGGTG CAGCGGGGGCTGTGGTGAGGGCCCTGGGAGGGGCAGGGGGATGCACGCAGACAGAGGCTCTGCCTGCCCG CAGAGTGCCAGCTGATGAAGACGGAGCGGCCCCGGCCCAACACCTTCATCATCCGCTGCCTGCAGTGGAC CACTGTCATCGAACGCACCTTCCATGTGGAGACTCCTGAGGAGCGGTACGTGGGCTGTGGCGGCCAGGCC AGGCACTTGGGCAGCCCCAGCGCTTAGGAGGGACACGGGGATGGCGGGGTGCTGGCACCTCTGCCTGTAG CCATCCTCACTCCCCAGTGCTCCCAGGCCCTCCTCAGAGCCCAGTTTGGAAACTGGCCCAGTCCTGCCTG TGGGGTTTGGGTGGGGAAACTGAGGCTGGAGATAAAAACTGGCTAGGGACCGGGTGCAGTGGCTCACGTC TATAATCTCGGCACTTTGGGAGGCCGAGGTGCGCAGATCACTTGAGACCAGGAGTTTGAGACTAGCCTGC CAACATGGTGAAACCCCCGTCTCTACTAAAAATATAAAACTTAGCTGGGTGTGGTGGTGCACACCTGTAA TCCCGGCTACTTGGGAGGCTGAGGCACAAGAATCGCTTGAACCCGAGAGGCAGAGGCTGCAGGAGCCGAG ATTTTACCACTGCACTCCAGCCAGGGCGATAGAGCAAGACTCCGTCTCAAAAAAAGAAAAACCCGGTGGA GAGGGCCAGTCCTCCTTGGGGGGCGGAGTCCTGCTTGGGAGGCGGAGTCCTGCTTGGGGGGGGCGGAGTC CTGCTGGGGGGCGGAGTCCTGCTGGGGGTTGGAGTCCGGTTGTGGGGACAGAGTCCTGCTGGGGGGCTAA GCCTGGGTGTCCCCCACGTCCAAGAGGGCTTCGTGACCCTGAGTGTATGTGGCCAGACCAGGTCAAGTGG TGGCCTCCTCAGGGCTGTCTCTGGGAACCCCGACAGCTGTGGAACCACGCTTGTGAGGCTGGCGGGTGGG TGAAAGACGTGGGGTGGAGCTCCTGATCTGGTACAGGCCTGCAGCCTCACCTGACCTCCTGCAGGGAGGA GTGGACAACCGCCATCCAGACTGTGGCTGACGGCCTCAAGAAGCAGGAGGAGGAGGAGATGGACTTCCGG TCGGGCTCACCCAGTGACAACTCAGGGGCTGAAGAGATGGAGGTGTCCCTGGCCAAGCCCAAGCACCGCG TGGTGAGGCCTGTCCCCACTTCTGCCTGTGCCTGGGGCTGCCTTGGACTGTGGAGGGCTGGGTGGGTCAT GGGGTCCCAGCTCGGCCCAGGAGACACTCAGCACTCCACGGCATCTCCACCTAGGCCGGTTTTCCATGTA GGGCGCAGCTGCTTCCCAGGTGGGTCCTCTTCCCCATGTCAGAGGAAAACTGGGGTTGCTGAGCCCTGCC AGGCTTGGGCAATGTTACCCCACCCTTCCCTGAACCCCATGCTCTGAGCTGGGGCCGCAGCCATGTGTTC CCTGTAAGCCTGGACTCCCCGCTGAGCCCAGTAGGCCACCAGGTGTGAAGTGGACGCCTCTCCTGGCTCT GCCTCCGACTCTGGGGCCCCTCATGCCACCCCACGCATGCCGACCAGCTGGGCACTGTTGGCAGCGCCGC TTGCTGACCCTGGTGCCTGCCCATAGACCATGAACGAGTTTGAGTACCTGAAGCTGCTGGGCAAGGGCAC TTTCGGCAAGGTGATCCTGGTGAAGGAGAAGGCCACAGGCCGCTACTACGCCATGAAGATCCTCAAGAAG GAAGTCATCGTGGCCAAGGTGGGGCCGGGGCGGTGGGGCAGGGTGGAGATGAGGGTGCGGGGTGGCAGCT CACCCAGCCCTGCTTTACAGGACGAGGTGGCCCACACACTCACCGAGAACCGCGTCCTGCAGAACTCCAG GCACCCCTTCCTCACAGTGAGTGGGAGCCCAGATGGGGCTGAAGGGCTGGGGCCAGGTAGCGACTCCTGG GGCTGTCTCTAGGGGACGATGTCCTGTCTTCTTGGGCACGTGAGGGCTTTACACACCGTGGACTCCGCCG CTGGTGAGACAGGCCTGCCCTGGAGGGTCAGGCTGTGGAGGTGCCCAGTGTGGGCTAGGGGCTGTGCTCG CTGCTCCCGTGTGCGGGCAGGTGGGTGGGGCAGGTGGCCCTGGTCTTCCTTGCACTCTGCCGAGGCTCCA GGAGGCCCCAGCTCCCCATGCCCTGCAGCCCTGCCTGCCAGGCTTTTGTTGAGGCCCGGGCTCTGTCCTG CAGAACCTGTTCTGGGGACTTGGCCCAGGAGGTATTTACTGTGAAGGGGGCCAGGGTCCAGCCACTTGGT TAGTTCCAGGTCACTGTGTTTGGGGACGATTCTCCTGCAGATGGGGCCTTTGCTTTAAAAGCACAGTCGC CTGTGGTGGAAGGCGGGAGGGTGGGTCTCGCCTGGGAGGGTGTGTCCTCCCTTTGCGAAGGCCCTGGTGC TGGGAGCACTGTCCCCTGCTGAGGTCCCAACTCACCCTGGAGGACCTGAGCCCAGGCCACCTTGCTCACC TTTCAAACACTCCTTGGCACCTCAGGGGCTGCCGGGGCCCAGCCTGATGGTGGCGTGGCATGAGGCAGTG TGGTGTGGGGCAGTGTGGTGTGGGGCAGCGTGGCATGGGGGCAGTGTGATGTGGGGGTGTATGGTGTGGG GCAGTGTGATGGGGTGTGTGGTGTGGGGCAGTGTGGTATCGGGCGGTGTGGTATCAGGCAGCGTGGTGTC GGGCAGTGTGGTGTGGGGCTACGGGCGGTGTGGTATCAGGCGACGTGGTATCAAGCAGCGTGGTGTCGGG CAGCGTGGTGCGGGGCTGCCGTCCTGCCTGTGGGGCCGCAGTTCCAGCTCCCCTTCCTTGCAGGCCCTGA AGTACTCTTTCCAGACCCACGACCGCCTCTGCTTTGTCATGGAGTACGCCAACGGGGGCGAGGTAGGGGC TGGGGCTGCGGGGGATGGACTTCGCGGCCTGTGGGCCGCCCATGGTGGGGCCGGTCCTTCCCGGAGCCTC GGCTACTCTCCATGGCACCAGACGGTGCTCCCTGCTGGGTGGGTGGTGTGATGCCTGCCCAGGCAGCTGC CTGCTGTGGGGTGACTTGTTCCTGCTGAGTTAGGGCTTCTGAGACTTTCCAGGCCCCCGTGCCCTCTGGT GGCTGGTCCCTTCCCTGTGCAATGCCGAGACCCGGTCTGAGAAACCCCAGCCCTGCAGGCCATGGGGGCA GAGGCCCGAGCCACGGCTGTGCCTCAGGTTGCGCCTCCCGCAGCTGTTCTTCCACCTGTCCCGGGAGCGT GTGTTCTCCGAGGACCGGGCCCGCTTCTATGGCGCTGAGATTGTGTCAGCCCTGGACTACCTGCACTCGG AGAAGAACGTGGTGTACCGGGACCTCAAGGTGCGCTGGCGGGCAGGCAGGGGGGCAGGGCCCTGGGGGCC TGGCGGCACTGACCTGAGGCCACCTTTCCCCTAGCTGGAGAACCTCATGCTGGACAAGGACGGGCACATT AAGATCACAGACTTCGGGCTGTGCAAGGAGGGGATCAAGGACGGTGCCACCATGAAGACCTTTTGCGGCA CACCTGAGTACCTGGCCCCCGAGGTGTGCGCCCCACCTGCGTGCATACGCGTTGCTGCGTCCCCACGTCC TGAGCACACGCAATGCTGTGTCCTCTCTGTGCCCCAAGCACGTCACACCTCCCCCGGCAGTGTCCCGGAC ACCCCTTGATGCCGAGTCCTGCCCATCTGCCACCCGTGCAGGTGCTGGAGGACAATGACTACGGCCGTGC AGTGGACTGGTGGGGGCTGGGCGTGGTCATGTACGAGATGATGTGCGGTCGCCTGCCCTTCTACAACCAG GACCATGAGAAGCTTTTTGAGCTCATCCTCATGGAGGAGATCCGCTTCCCGCGCACGCTTGGTCCCGAGG CCAAGTCCTTGCTTTCAGGGCTGCTCAAGAAGGACCCCAAGCAGAGGTGAGGGCCGCCCATCCCAGCTAC AGGCTACACCTCCATCCCCTCATCCCCAGGCTGCACCTGCCCCTGCGCCAGGCGGTCCTGGCACCTCCCA GACTACACTGATAGCCAAAGCTTGATGTCCTTGGCCAGGGCTGATCTCCAAAGCCTCAGGCCCAAGCAGA GTGGCGGGCAGGCCGGGGTCAGTTGGGCCTCTGTCCCCAACCCTGCAGCCTGCACCCACCCACTCAGGAA GCCCCTGCCCTGCCGTGAGCTCTGTGGTGCTTTGCTACCCACAGCTGCTCAGGGACGCTGCACCACCGGC TCCCCTCCCTGGCCCCGGAACGTCCTGTCTGGCGGGCCCTACATCACAGGAGGAAGGGGCCTGAACCCAG GGCCTGGGCAGGTGGCGGTACCGACACTGTGGCCTTGTTTCCTGCCTGCAGGCTTGGCGGGGGCTCCGAG GACGCCAAGGAGATCATGCAGCATCGCTTCTTTGCCGGTATCGTGTGGCAGCACGTGTACGAGAAGAAGG TGCGGCTGCTCCCCGCATATTCACGCGCACGCATGCTCCCCACATATCCACACTCACGCATGCACGTGGC ACGCTCGCCAGATTTCCCACACACTCGCCCTCACCTCAGGAGCCTGCTGCAGTCCTGGTACAAGGAGGGC CTTGCTGCACCAACCTCAGCGCCTGGTGCTCAGAGGCTCTGGCACTGCCGGGTTCCACCAGGAAACTGGC CTGGTCCTCATTTCCTCCTCCCCTCGGAGGTGTGTCACACTCTGAGTTTCCTCCTCCCCTCGGAGGTGTG TCACACTCTGAGTGCCAGCCTTGGGGTTCCCTTCCCTGACGCTGTGCAGTGAAGGCTGGCTGGTGGTGGA CCAGGGGTGCTGCCCCTTGGCCTCCACGAGTTCCTCCTGTTTGACCTCAATCCCTTCTGCCGCAAGGAGA GCCCAGCCCTATTTCTGGCTGTGCAGGGACAGGGACAGCACCTACTTTTCTGGCACATGGGGGAGTCCGC CCTGGAGGGAGGCAGCTCTTTCTGCATGAGTCGCCATCCTGGGTGCTCATCTTTCAGGGACCCTAGGAGC CCTGGCCATCACCCCAGCTGATGGGGTCTGCCAGCTGGGTTCGGAAGCCTGCACTCTGAGATGCTGGGTG CCCTGTCACCAGGTGTGCTTCTGCCCCGTTCCCAGCCTGCCCCTCCCCTGAATGCCTGTCCTAGGCTGTG TGCAGCTGGTCGGGCTGGGCAGCCCTGGGACCCAGCTGGGCACCTGTTCTCCCATTAACACAGGGTGCCC TGGTCCTGGTCCCCGTTCCTGCCTTGAGGCCTGCCACCCTCCTGCCCTGCCCTCCAAGGGTATGGGGGGC CTGGGCAGTGCTCAACCTCTGCCCAGCCTTGACCAGAGACCTTGCTAATTGACAATGGACAATGCTGGTG CCCAGCCCAGACTCTGGGGTGGGGCAGTGCTTGAGGGGGTCCTTGACTGTGGGACCTGAGGGGCTCTCTG GCAGCTCCTCACGTGTGCACATCACCTTATAGTCACCCTTCATCCTGGGTCATTGAGAGTCCTGTCTGCA GCCAGATGCCAGCAGGCTGTGGTCCTGTAGTCCCTGAGCCATGGAGGCAGGGTGGGCTCATCCTGTGCAC CTTGTTCCACAGTCTCCCTCTTTCCCAATTTACAAGAAGACCAATAAGAAAAATAAGAAAACAAGAAAGA AAAAGGAAAAATAAAGTTATCACCTCCTGGTAGCAGGGAGGGTCTCTCAGAGCTGGGCTGCACTACCTCC TGTCGCCTGCTGGGGCTGCTGTGAGGGCAGCTTTGCGTCTCAGCTGTTGAGGGTTGTCTCCGTGCTCCTG CACCCCTCATGTCCCTCCCTCCCAGAGCTGCCTCTGTGGGGGGCTGGTGGCTTGCTGCTCTCTGACATCA GTCCTGCCTGGAGACCCCTTGGAGATCCAGGTGCTTTGAAGGTCTTGAGCACACTTGAGGGTGTGCTGGG AGTGGGGAGCGAAGCTCATGACTGTCCCGTCTGCCCACCTCTGCAGCTCAGCCCACCCTTCAAGCCCCAG GTCACGTCGGAGACTGACACCAGGTATTTTGATGAGGAGTTCACGGCCCAGATGATCACCATCACACCAC CTGACCAAGGTGAGGGGCCACTGCCTGCCCCCGCCCACTCCCTTTTCTCTCCACACTCAGAGAGGCCTGC AGTGTTCAGCTTTTTTGGCTTCAGATGTTTTAAAATCTAAATATTTAAAAAGGTTCCTTTTGGAGAGTGC CAATGATCAGGGTGGGAGGCAGTGCTCTGAGGGCCCAGGTCCCTGTGTCAATCTGTGGGGCCCTGTCTCA GTTTCCTGGCAGTATGGCAGCGTGCTGGCCGTGCTTTAAGAGGTTGGCTTCCTACTGGAGCTGTGGGTGG GTGGAGGTGGCAGGGAGGTGGGGCACCGGGGTCTGAGCTGTCTACACCCACAGATGACAGCATGGAGTGT GTGGACAGCGAGCGCAGGCCCCACTTCCCCCAGTTCTCCTACTCGGCCAGCGGCACGGCCTGAGGCGGCG GTGGACTGCGCTGGACGATAGCTTGGAGGGATGGAGAGGCGGCCTCGTGCCATGATCTGTATTTAATGGT TTTTATTTCTCGGGTGCATTTGAGAGAAGCCACGCTGTCCTCTCGAGCCCAGATGGAAAGACGTTTTTGT GCTGTGGGCAGCACCCTCCCCCGCAGCGGGGTAGGGAAGAAAACTATCCTGCGGGTTTTAATTTATTTCA TCCAGTTTGTTCTCCGGGTGTGGCCTCAGCCCTCAGAACAATCCGATTCACGTAGGGAAATGTTAAGGAC TTCTGCAGCTATGCGCAATGTGGCATTGGGGGGCCGGGCAGGTCCTGCCCATGTGTCCCCTCACTCTGTC AGCCAGCCGCCCTGGGCTGTCTGTCACCAGCTATCTGTCATCTCTCTGGGGCCCTGGGCCTCAGTTCAAC CTGGTGGCACCAGATGCAACCTCACTATGGTATGCTGGCCAGCACCCTCTCCTGGGGGTGGCAGGCACAC AGCAGCCCCCCAGCACTAAGGCCGTGTCTCTGAGGACGTCATCGGAGGCTGGGCCCCTGGGATGGGACCA GGGATGGGGGATGGGCCAGGGTTTACCCAGTGGGACAGAGGAGCAAGGTTTAAATTTGTTATTGTGTATT ATGTTGTTCAAATGCATTTTGGGGGTTTTTAATCTTTGTGACAGGAAAGCCCTCCCCCTTCCCCTTCTGT GTCACAGTTCTTGGTGACTGTCCCACCGGGAGCCTCCCCCTCAGATGATCTCTCCACGGTAGCACTTGAC CTTTTCGACGCTTAACCTTTCCGCTGTCGCCCCAGGCCCTCCCTGACTCCCTGTGGGGGTGGCCATCCCT GGGCCCCTCCACGCCTCCTGGCCAGACGCTGCCGCTGCCGCTGCACCACGGCGTTTTTTTACAACATTCA ACTTTAGTATTTTTACTATTATAATATAATATGGAACCTTCCCTCCAAATTCTTCAATAAAAGTTGCTTT TCAAA    Download   Select all
Length	26395
OMIM ID	164730
HGNC ID	HGNC:391
Unigene ID	Hs.525622
Ensembl ID	ENSG00000142208
PharmGKB ID	PA24684

mRNA Information

mRNA ID	NM_001014431.1
Exon	join(1..260,3022..3146,15528..15656,18974..19085, 19945..20092,20537..20668,20741..20806,21764..21832, 22164..22289,22365..22493,22652..22866,23292..23379, 24897..24999,25324..26395)
mRNA Sequence	Download   Select all
Length	2794

CDS Information

   

Location	341..1783
CDS Sequence	>lcl|NM_001014431.1_cds_NP_001014431.1_1 [gene=AKT1] [protein=RAC-alpha serine/threonine-protein kinase] [protein_id=NP_001014431.1] [location=341..1783] ATGAGCGACGTGGCTATTGTGAAGGAGGGTTGGCTGCACAAACGAGGGGAGTACATCAAGACCTGGCGGC CACGCTACTTCCTCCTCAAGAATGATGGCACCTTCATTGGCTACAAGGAGCGGCCGCAGGATGTGGACCA ACGTGAGGCTCCCCTCAACAACTTCTCTGTGGCGCAGTGCCAGCTGATGAAGACGGAGCGGCCCCGGCCC AACACCTTCATCATCCGCTGCCTGCAGTGGACCACTGTCATCGAACGCACCTTCCATGTGGAGACTCCTG AGGAGCGGGAGGAGTGGACAACCGCCATCCAGACTGTGGCTGACGGCCTCAAGAAGCAGGAGGAGGAGGA GATGGACTTCCGGTCGGGCTCACCCAGTGACAACTCAGGGGCTGAAGAGATGGAGGTGTCCCTGGCCAAG CCCAAGCACCGCGTGACCATGAACGAGTTTGAGTACCTGAAGCTGCTGGGCAAGGGCACTTTCGGCAAGG TGATCCTGGTGAAGGAGAAGGCCACAGGCCGCTACTACGCCATGAAGATCCTCAAGAAGGAAGTCATCGT GGCCAAGGACGAGGTGGCCCACACACTCACCGAGAACCGCGTCCTGCAGAACTCCAGGCACCCCTTCCTC ACAGCCCTGAAGTACTCTTTCCAGACCCACGACCGCCTCTGCTTTGTCATGGAGTACGCCAACGGGGGCG AGCTGTTCTTCCACCTGTCCCGGGAGCGTGTGTTCTCCGAGGACCGGGCCCGCTTCTATGGCGCTGAGAT TGTGTCAGCCCTGGACTACCTGCACTCGGAGAAGAACGTGGTGTACCGGGACCTCAAGCTGGAGAACCTC ATGCTGGACAAGGACGGGCACATTAAGATCACAGACTTCGGGCTGTGCAAGGAGGGGATCAAGGACGGTG CCACCATGAAGACCTTTTGCGGCACACCTGAGTACCTGGCCCCCGAGGTGCTGGAGGACAATGACTACGG CCGTGCAGTGGACTGGTGGGGGCTGGGCGTGGTCATGTACGAGATGATGTGCGGTCGCCTGCCCTTCTAC AACCAGGACCATGAGAAGCTTTTTGAGCTCATCCTCATGGAGGAGATCCGCTTCCCGCGCACGCTTGGTC CCGAGGCCAAGTCCTTGCTTTCAGGGCTGCTCAAGAAGGACCCCAAGCAGAGGCTTGGCGGGGGCTCCGA GGACGCCAAGGAGATCATGCAGCATCGCTTCTTTGCCGGTATCGTGTGGCAGCACGTGTACGAGAAGAAG CTCAGCCCACCCTTCAAGCCCCAGGTCACGTCGGAGACTGACACCAGGTATTTTGATGAGGAGTTCACGG CCCAGATGATCACCATCACACCACCTGACCAAGATGACAGCATGGAGTGTGTGGACAGCGAGCGCAGGCC CCACTTCCCCCAGTTCTCCTACTCGGCCAGCGGCACGGCCTGA    Download   Select all
CCDS ID	CCDS9994.1

Protein Information

      

Protein ID	NP_001014431.1
Protein Name	v-akt murine thymoma viral oncogene homolog 1
Molecular Wt. (Da)	55556
Protein Sequence	Download   Select all
Length	480
Uniprot ID	P31153
Ensembl Protein ID	ENSP00000303147

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	124
S	Phosphorylation	129
T	Phosphorylation	450
Y	Phosphorylation	474
S	Phosphorylation	124
S	Phosphorylation	129
T	Phosphorylation	450
Y	Phosphorylation	474
S	Phosphorylation	124
S	Phosphorylation	129
T	Phosphorylation	450
Y	Phosphorylation	474
Y	Phosphorylation	315
Y	Phosphorylation	326
Y	Phosphorylation	315
Y	Phosphorylation	326
Y	Phosphorylation	315
Y	Phosphorylation	326
D	Proteolytic Cleavage	462
D	Proteolytic Cleavage	462
D	Proteolytic Cleavage	462
S	Phosphorylation	473
S	Phosphorylation	473
S	Phosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
T	Dephosphorylation	308
T	Dephosphorylation	308
T	Dephosphorylation	308
T	Phosphorylation	308
T	Phosphorylation	308
T	Phosphorylation	308
S	Dephosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
S	Dephosphorylation	473
T	Phosphorylation	308
S	Phosphorylation	473
S	Dephosphorylation	473
S	Phosphorylation	473
S	Phosphorylation	473
S	Phosphorylation	473
S	Phosphorylation	126;-
S	Phosphorylation	126;-
S	Phosphorylation	126;-
S	Phosphorylation	122
S	Phosphorylation	122
S	Phosphorylation	122

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
331	XIAP	2094	NP_001158.2	in vitro;in vivo	14645242
334	APLP2	103	NP_001633.1	in vivo	10490823
367	AR	2437	NP_000035.2	in vitro;in vivo	114   044   601   115   637   000   000   000
572	BAD	4409	NP_004313.1	in vitro;in vivo	9381178
672	BRCA1	218	NP_009231.2	in vitro;in vivo	10542266
673	BRAF	1264	NP_004324.2	in vitro;in vivo	1   086   935   911   410   590
842	CASP9	3756	NP_001220.2	in vitro	9812896
1026	CDKN1A	298	NP_510867.1	in vitro;in vivo	11756412
1027	CDKN1B	2867	NP_004055.1	in vitro;in vivo	12244301
1111	CHEK1	4356	NP_001265.2	in vitro	12062056
1147	CHUK	2811	NP_001269.3	in vitro;in vivo	10485710
1326	MAP3K8	1863	NP_005195.2	in vivo	12138205
1385	CREB1	442	NP_604391.1	in vitro	9829964
1901	S1PR1	3578	NP_001391.2	in vitro;in vivo	11583630
1978	EIF4EBP1	3746	NP_004086.1	in vitro	11777913
2033	EP300	4078	NP_001420.2	in vitro	11116148
2099	ESR1	589	NP_000116.2	in vitro;in vivo	11139588
2100	ESR2	3390	NP_001428.1	in vivo	15001646
2146	EZH2	3342	NP_004447.2	in vitro;in vivo	16224021
2175	FANCA	6186	NP_000126.2	in vitro	11855836
2308	FOXO1	645	NP_002006.2	in vitro;in vivo	10358014
2309	FOXO3	4061	NP_001446.1	in vitro;in vivo	10102273
2475	MTOR	3134	NP_004949.1	in vitro	1   143   872   310   910   060
2623	GATA1	2372	NP_002040.1	in vitro;in vivo	16107690
2624	GATA2	673	NP_116027.2	in vivo	15837948
2931	GSK3A	6002	NP_063937.2	in vitro;in vivo	11   035   810   118   845   900   000   000
2932	GSK3B	5418	NP_002084.2	in vitro;in vivo	110   358   108   524   413
3064	HTT	883	NP_002102.4	in vitro;in vivo	12062094
3162	HMOX1	782	NP_002124.1	in vitro;in vivo	15581622
3164	NR4A1	744	NP_002126.2	in vitro;in vivo	11274386
3320	HSP90AA1	777	NP_001017963.2	in vivo	1   099   545   719   356   720
3551	IKBKB	4462	NP_001547.1	in vitro;in vivo	10485711
3615	IMPDH2	895	NP_000875.2	in vitro;in vivo;yeast 2-hybrid	10930578
3654	IRAK1	2235	NP_001560.2	in vitro;in vivo	11976320
3667	IRS1	943	NP_005535.1	in vivo	10497255
3690	ITGB3	1428	NP_000203.2	in vitro	10896934
3858	KRT10	1021	NP_000412.3	in vivo	11585925
4087	SMAD2	3221	NP_005892.1	in vivo	16362038
4088	SMAD3	4380	NP_005893.1	in vivo	16362038
4089	SMAD4	2995	NP_005350.1	in vivo	16362038
4092	SMAD7	4241	NP_005895.1	in vivo	16362038
4193	MDM2	1272	NP_002383.2	in vitro;in vivo	121   452   041   150   491   000   000   000
4194	MDM4	4082	NP_002384.2	in vitro	16163388
4217	MAP3K5	3904	NP_005914.1	in vitro;in vivo	11154276
4234	METTL1	6834	NP_005362.3	in vitro	15861136
4296	MAP3K11	2502	NP_002410.1	in vitro;in vivo	12458207
4303	FOXO4	2070	NP_005929.2	in vitro;in vivo	11   313   479   102   171   400   000   000   000   000   000
4486	MST1R	2545	NP_002438.2	in vitro	12919677
4687	NCF1	1990	NP_000256.3	in vitro	12734380
4846	NOS3	1224	NP_000594.2	in vitro	1   169   657   910   376   600
4904	YBX1	1095	NP_004550.2	in vitro;in vivo	16354698
5058	PAK1	3995	AAC24716.1	in vivo	12138087
5140	PDE3B	3626	NP_000913.2	in vitro;in vivo	10454575
5164	PDK2	3955	NP_002602.2	in vitro	10438924
5208	PFKFB2	1383	NP_006203.2	in vitro	12853467
5295	PIK3R1	1381	NP_852664.1	in vitro	10527852
5591	PRKDC	2941	NP_008835.5	in vitro	15262962
5728	PTEN	3431	NP_000305.3	in vitro;in vivo	120   772   561   086   665   000   000   000
5770	PTPN1	1477	NP_002818.1	in vitro;in vivo	11579209
5879	RAC1	3627	NP_061485.1	in vitro;in vivo	10617634
5894	RAF1	1265	NP_002871.1	in vitro;in vivo	1   057   674   219   058   870
6310	ATXN1	3333	NP_000323.2	in vitro;in vivo	1   275   770   712   741   980
6416	MAP2K4	3213	NP_003001.1	in vitro;in vivo	11707464
6772	STAT1	2777	NP_009330.1	in vivo	15284024
7015	TERT	1754	NP_003210.1	in vitro;in vivo	10224060
7249	TSC2	1850	NP_000539.2	in vitro	1   243   823   912   150   910
7534	YWHAZ	3183	NP_003397.1	in vitro;in vivo	11956222
8349	HIST2H2BE	3494	NP_003519.1	in vivo	9973250
8682	PEA15	4579	NP_003759.1	in vitro;in vivo	12808093
9545	RAB3D	5070	NP_004274.1	in vitro	11903042
9846	GAB2	5866	NP_036428.1	in vitro;in vivo	11782427
10018	BCL2L11	4828	NP_619527.1	in vitro;in vivo	16282323
10395	DLC1	5035	NP_872584.2	in vivo;yeast 2-hybrid	16338927
10413	YAP1	9424	NP_001123617.1	in vitro;in vivo	12535517
10603	SH2B2	16097	NP_066189.3	in vitro;in vivo	16141217
11331	PHB2	17843	NP_009204.1	in vivo;yeast 2-hybrid	15173318
26060	APPL1	5053	NP_036228.1	in vitro;in vivo	12621049
55704	CCDC88A	11131	NP_001129069.1	in vitro;in vivo	16139227
65125	WNK1	5570	NP_061852.2	in vitro;in vivo	14611643
79026	AHNAK	14684	NP_001611.1	in vitro	11535620
84335	AKT1S1	12441	NP_115751.2	in vitro;in vivo	1   252   443   914   973   220
133522	PPARGC1B	10594	NP_573570.2	in vitro	17554339

Pathway Information

                                                                                                                                                                                                                                                                                                                                                                                                                                    

Pathway Name	Pathway ID
Acute myeloid leukemia	hsa05221
Adipocytokine signaling pathway	hsa04920
Adrenergic signaling in cardiomyocytes	hsa04261
AGE-RAGE signaling pathway in diabetic complications	hsa04933
AMPK signaling pathway	hsa04152
Apoptosis	hsa04210
B cell receptor signaling pathway	hsa04662
cAMP signaling pathway	hsa04024
Carbohydrate digestion and absorption	hsa04973
Central carbon metabolism in cancer	hsa05230
cGMP-PKG signaling pathway	hsa04022
Chagas disease (American trypanosomiasis)	hsa05142
Chemokine signaling pathway	hsa04062
Choline metabolism in cancer	hsa05231
Cholinergic synapse	hsa04725
Chronic myeloid leukemia	hsa05220
Colorectal cancer	hsa05210
Dopaminergic synapse	hsa04728
Endometrial cancer	hsa05213
Epstein-Barr virus infection	hsa05169
ErbB signaling pathway	hsa04012
Estrogen signaling pathway	hsa04915
Fc epsilon RI signaling pathway	hsa04664
Fc gamma R-mediated phagocytosis	hsa04666
Focal adhesion	hsa04510
FoxO signaling pathway	hsa04068
Glioma	hsa05214
Glucagon signaling pathway	hsa04922
Hepatitis B	hsa05161
Hepatitis C	hsa05160
HIF-1 signaling pathway	hsa04066
HTLV-I infection	hsa05166
Influenza A	hsa05164
Insulin resistance	hsa04931
Insulin signaling pathway	hsa04910
Jak-STAT signaling pathway	hsa04630
Longevity regulating pathway - mammal	hsa04211
Longevity regulating pathway - multiple species	hsa04213
MAPK signaling pathway	hsa04010
Measles	hsa05162
Melanoma	hsa05218
mTOR signaling pathway	hsa04150
Neurotrophin signaling pathway	hsa04722
Non-alcoholic fatty liver disease (NAFLD)	hsa04932
Non-small cell lung cancer	hsa05223
Osteoclast differentiation	hsa04380
Pancreatic cancer	hsa05212
Pathways in cancer	hsa05200
Phospholipase D signaling pathway	hsa04072
PI3K-Akt signaling pathway	hsa04151
Platelet activation	hsa04611
Progesterone-mediated oocyte maturation	hsa04914
Prolactin signaling pathway	hsa04917
Prostate cancer	hsa05215
Proteoglycans in cancer	hsa05205
Rap1 signaling pathway	hsa04015
Ras signaling pathway	hsa04014
Regulation of lipolysis in adipocytes	hsa04923
Renal cell carcinoma	hsa05211
Signaling pathways regulating pluripotency of stem cells	hsa04550
Small cell lung cancer	hsa05222
Sphingolipid signaling pathway	hsa04071
T cell receptor signaling pathway	hsa04660
Thyroid hormone signaling pathway	hsa04919
Tight junction	hsa04530
TNF signaling pathway	hsa04668
Toll-like receptor signaling pathway	hsa04620
Toxoplasmosis	hsa05145
Tuberculosis	hsa05152
VEGF signaling pathway	hsa04370

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd05594	124-479	STKc_PKB_alpha
cl21453	124-479	PKc_like superfamily
cd01241	4-111	PH_PKB
cl17171	4-111	PH-like superfamily
cd05571	154-477	STKc_PKB
cd05595	154-477	STKc_PKB_beta
cd05593	133-478	STKc_PKB_gamma
cd05570	154-474	STKc_PKC
cd05575	154-474	STKc_SGK
cd05123	156-408	STKc_AGC
cd05589	150-476	STKc_PKN
cd05592	154-474	STKc_nPKC_theta_like
cd05587	153-474	STKc_cPKC
cd05584	153-476	STKc_p70S6K
cd05603	154-475	STKc_SGK2
cd05580	148-439	STKc_PKA_like
cd05591	154-474	STKc_nPKC_epsilon
cd05604	153-447	STKc_SGK3
cd05590	154-454	STKc_nPKC_eta
cd05616	149-474	STKc_cPKC_beta
cd05602	139-475	STKc_SGK1
cd05586	156-443	STKc_Sck1_like
cd05588	154-455	STKc_aPKC
cd05585	155-445	STKc_YPK1_like
cd05615	144-454	STKc_cPKC_alpha
cd05582	154-453	STKc_RSK_N
cd14209	149-440	STKc_PKA
cd05619	144-442	STKc_nPKC_theta
cd05617	147-455	STKc_aPKC_zeta
cd05573	148-440	STKc_ROCK_NDR_like
cd05620	154-474	STKc_nPKC_delta
cd05614	149-452	STKc_MSK2_N
cd05618	139-455	STKc_aPKC_iota
cd05583	156-411	STKc_MSK_N
cd05612	149-439	STKc_PRKX_like
cd05574	150-429	STKc_phototropin_like
cd05579	158-413	STKc_MAST_like
cd05599	148-474	STKc_NDR_like
cd05613	150-427	STKc_MSK1_N
cd14003	150-407	STKc_AMPK-like
cd05117	150-407	STKc_CAMK
cd05572	156-414	STKc_cGK
cd14007	149-407	STKc_Aurora
cd05581	148-408	STKc_PDK1
cd05578	150-408	STKc_Yank1
cd05577	156-427	STKc_GRK
cd05601	148-440	STKc_CRIK
cd05598	150-474	STKc_LATS
cd05597	149-453	STKc_DMPK_like
cd05605	150-427	STKc_GRK4_like
cd05609	149-413	STKc_MAST
cd05600	138-440	STKc_Sid2p_like
cd05629	148-454	STKc_NDR_like_fungal
cd05596	142-440	STKc_ROCK
cd05611	153-413	STKc_Rim15_like
cd08215	150-408	STKc_Nek
cd05630	150-427	STKc_GRK6
cd14663	150-407	STKc_SnRK3
cd05606	155-427	STKc_beta_ARK
cd05631	150-427	STKc_GRK4
cd05624	143-439	STKc_MRCK_beta
cd05608	150-427	STKc_GRK1
cd05633	145-443	STKc_GRK3
cd05632	148-427	STKc_GRK5
cd05610	146-445	STKc_MASTL
cd00180	156-405	PKc
cd05623	139-452	STKc_MRCK_alpha
cd14008	156-408	STKc_LKB1_CaMKK
cd14083	150-391	STKc_CaMKI
cd06606	154-408	STKc_MAPKKK
cd14073	150-391	STKc_NUAK
cd05607	150-427	STKc_GRK7
cd14081	154-408	STKc_BRSK1_2
cd14099	154-408	STKc_PLK
cd14095	149-406	STKc_DCKL
cd14079	154-408	STKc_AMPK_alpha
cd14223	149-455	STKc_GRK2
cd05622	144-440	STKc_ROCK1
cd14002	148-407	STKc_STK36
cd14014	153-391	STKc_PknB_like
cd14078	150-406	STKc_MELK
cd14167	150-410	STKc_CaMKI_alpha
cd05122	149-408	PKc_STE
cd05621	149-440	STKc_ROCK2
cd14080	153-408	STKc_TSSK-like
cd14166	150-410	STKc_CaMKI_gamma
cd05627	147-440	STKc_NDR2
cd14161	142-391	STKc_NUAK2
cd14084	154-405	STKc_Chk2
cd14093	155-408	STKc_PhKG
cd06623	148-407	PKc_MAPKK_plant_like
cd14009	156-393	STKc_ATG1_ULK_like
cd14072	150-391	STKc_MARK
cd05625	150-439	STKc_LATS1
cd05626	150-439	STKc_LATS2
cd05628	149-440	STKc_NDR1
cd14097	156-405	STKc_STK33
cd14098	149-405	STKc_Rad53_Cds1
cd14071	150-408	STKc_SIK
cd14116	146-405	STKc_Aurora-A
cd14077	150-407	STKc_Kin1_2
cd14006	156-406	STKc_MLCK-like
cd14169	156-410	STKc_CaMKI_beta
cd14076	156-405	STKc_Kin4
cd14096	148-405	STKc_RCK1-like
cd14075	156-407	STKc_NIM1
cd14162	150-389	STKc_TSSK4-like
cd06614	150-409	STKc_PAK
cd14168	150-410	STKc_CaMKI_delta
cd14087	149-392	STKc_PSKH1
cd14185	150-405	STKc_DCKL3
cd08530	150-393	STKc_CNK2-like
cd13999	156-391	STKc_MAP3K-like
cd14086	148-405	STKc_CaMKII
cd14117	144-424	STKc_Aurora-B_like
cd14091	149-433	STKc_RSK_C
cd08529	149-404	STKc_FA2-like
cd14085	150-410	STKc_CaMKIV
cd14074	154-405	STKc_SNRK
cd14103	156-406	STKc_MLCK
cd14165	156-408	STKc_TSSK1_2-like
cd13994	156-408	STKc_HAL4_like
cd05118	150-408	STKc_CMGC
cd14118	156-392	STKc_CAMKK
cd14662	150-405	STKc_SnRK2
cd14010	156-407	STKc_ULK4
cd14089	154-406	STKc_MAPKAPK
cd14092	154-392	STKc_MSK_C
cd06627	154-408	STKc_Cdc7_like
cd14189	154-408	STKc_PLK3
cd14665	150-392	STKc_SnRK2-3
cd06632	154-407	STKc_MEKK1_plant
cd08217	149-408	STKc_Nek2
cd14184	154-405	STKc_DCKL2
cd14186	149-392	STKc_PLK4
cd06609	148-407	STKc_MST3_like
cd14119	156-408	STKc_LKB1
cd14188	154-408	STKc_PLK2
cd14181	155-408	STKc_PhKG2
cd06626	154-407	STKc_MEKK4
cd14106	154-408	STKc_DRAK
cd14105	150-405	STKc_DAPK
cd14070	154-391	STKc_HUNK
cd14183	154-405	STKc_DCKL1
cd06605	148-408	PKc_MAPKK
cd14187	146-391	STKc_PLK1
cd07829	150-408	STKc_CDK_like
cd14090	155-405	STKc_Mnk
cd08222	150-407	STKc_Nek11
cd14179	154-392	STKc_MSK1_C
cd08218	153-391	STKc_Nek1
cd14004	150-408	STKc_PASK
cd08219	149-391	STKc_Nek3
cd14005	150-408	STKc_PIM
cd14182	149-408	STKc_PhKG1
cd06625	154-408	STKc_MEKK3_like
cd14121	156-392	STKc_ULK3
cd14082	154-391	STKc_PKD
cd06611	156-409	STKc_SLK_like
cd06613	149-408	STKc_MAP4K3_like
cd08225	150-391	STKc_Nek5
cd07833	148-408	STKc_CDKL
cd14088	161-407	STKc_CaMK_like
cd06648	156-409	STKc_PAK_II
cd14196	150-392	STKc_DAPK2
cd08528	149-391	STKc_Nek10
cd14172	154-392	STKc_MAPKAPK3
cd14194	148-392	STKc_DAPK1
cd14171	156-405	STKc_MAPKAPK5
cd06612	148-408	STKc_MST1_2
cd14120	156-407	STKc_ULK1_2-like
cd06647	137-408	STKc_PAK_I
cd14069	148-408	STKc_Chk1
cd06656	136-408	STKc_PAK3
cd14199	147-392	STKc_CaMKK2
cd06654	136-408	STKc_PAK1
cd13990	153-391	STKc_TLK
cd14200	156-393	STKc_CaMKK1
cd06917	150-407	STKc_NAK1_like
cd08223	149-407	STKc_Nek4
cd14175	156-405	STKc_RSK1_C
cd06655	136-408	STKc_PAK2
cd07830	150-408	STKc_MAK_like
cd14195	150-392	STKc_DAPK3
cd14180	156-392	STKc_MSK2_C
cd14202	149-408	STKc_ULK1
cd06659	151-408	STKc_PAK6
cd14198	154-391	STKc_DRAK2
cd14174	154-405	STKc_Mnk1
cd06644	150-412	STKc_STK10
cd14173	154-405	STKc_Mnk2
cd14094	150-405	STKc_CASK
cd14191	156-392	STKc_MLCK1
cd13987	156-348	STKc_SBK1
cd14113	156-391	STKc_Trio_C
cd14176	137-405	STKc_RSK2_C
cd14111	157-386	STKc_SPEG_rpt2
cd13993	156-391	STKc_Pat1_like
cd06640	150-407	STKc_MST4
cd06610	148-408	STKc_OSR1_SPAK
cd14178	150-405	STKc_RSK3_C
cd14170	154-405	STKc_MAPKAPK2
cd14190	154-395	STKc_MLCK2
cd14201	146-392	STKc_ULK2
cd14197	156-405	STKc_DRAK1
cd08220	149-405	STKc_Nek8
cd13974	166-392	STKc_SHIK
cd07840	150-408	STKc_CDK9_like
cd06643	150-407	STKc_SLK
cd13996	148-391	STKc_EIF2AK
cd14192	154-408	STKc_MLCK3
cd14114	150-392	STKc_Twitchin_like
cd00192	154-391	PTKc
cd14137	153-408	STKc_GSK3
cd06608	148-407	STKc_myosinIII_N_like
cd07838	150-408	STKc_CDK4_6_like
cd07841	150-409	STKc_CDK7
cd13997	149-391	PKc_Wee1_like
cd06642	150-407	STKc_STK25
cd06657	156-409	STKc_PAK4
cd07834	150-411	STKc_MAPK
cd14177	150-409	STKc_RSK4_C
cd06658	156-408	STKc_PAK5
cd07832	149-408	STKc_CCRK
cd14164	150-391	STKc_TSSK6-like
cd14193	154-405	STKc_MLCK4
cd14039	156-401	STKc_IKK_alpha
cd14046	148-405	STKc_EIF2AK4_GCN2_rpt2
cd06641	150-407	STKc_MST3
cd06629	150-407	STKc_Bck1_like
cd13989	156-399	STKc_IKK
cd14059	156-353	STKc_MAP3K12_13
cd05576	159-408	STKc_RPK118_like
cd14163	154-387	STKc_TSSK3-like
cd06620	151-391	PKc_Byr1_like
cd14210	150-408	PKc_DYRK
cd14107	150-408	STKc_obscurin_rpt1
cd07851	143-409	STKc_p38
cd14061	155-349	STKc_MLK
cd14050	150-391	PKc_Myt1
cd07831	154-408	STKc_MOK
cd06630	154-408	STKc_MEKK1
cd07835	150-408	STKc_CDK1_CdkB_like
cd06653	154-349	STKc_MEKK3_like_u1
cd06645	144-407	STKc_MAP4K3
cd06652	154-349	STKc_MEKK2
cd08224	149-391	STKc_Nek6_7
cd14104	156-405	STKc_Titin
cd06628	155-407	STKc_Byr2_like
cd06615	149-409	PKc_MEK
cd07866	146-408	STKc_BUR1
cd06624	149-407	STKc_ASK
cd14041	143-392	STKc_TLK2
cd06646	135-407	STKc_MAP4K5
cd14038	156-391	STKc_IKK_beta
cd14115	156-391	STKc_Kalirin_C
cd06651	154-349	STKc_MEKK3
cd14066	156-351	STKc_IRAK
cd06621	148-349	PKc_Pek1_like
cd13978	156-354	STKc_RIP
cd08221	149-391	STKc_Nek9
cd07855	149-410	STKc_ERK5
cd14131	149-407	PKc_Mps1
cd14147	149-391	STKc_MLK3
cd06631	155-407	STKc_YSK4
cd14148	155-396	STKc_MLK2
cd14058	156-391	STKc_TAK1
cd14012	222-407	PK_eIF2AK_GCN2_rpt1
cd07846	148-408	STKc_CDKL2_3
cd07860	150-408	STKc_CDK2_3
cd14133	150-408	PKc_DYRK_like
cd14040	146-392	STKc_TLK1
cd06622	148-391	PKc_PBS2_like
cd13979	156-393	STKc_Mos
cd14022	247-408	PK_TRB2
cd14110	146-370	STKc_obscurin_rpt2
cd06650	148-357	PKc_MEK1
cd14145	144-391	STKc_MLK1
cd13983	152-408	STKc_WNK
cd08228	147-391	STKc_Nek6
cd06636	150-378	STKc_MAP4K4_6_N
cd14000	155-391	STKc_LRRK
cd14146	155-353	STKc_MLK4
cd06618	142-407	PKc_MKK7
cd14052	150-341	PTKc_Wee1_fungi
cd13985	153-391	STKc_GAK_like
cd07845	146-408	STKc_CDK10
cd14102	155-391	STKc_PIM3
cd14047	149-343	STKc_EIF2AK2_PKR
cd07836	150-408	STKc_Pho85
cd07865	148-408	STKc_CDK9
cd14024	230-405	PK_TRB3
cd14023	240-408	PK_TRB1
cd05081	150-342	PTKc_Jak3_rpt2
cd06638	148-407	STKc_myosinIIIA_N
cd14150	149-351	STKc_A-Raf
cd06637	150-407	STKc_TNIK
cd07877	149-404	STKc_p38alpha
cd07847	150-408	STKc_CDKL1_4
cd14049	147-391	STKc_EIF2AK1_HRI
cd05039	144-349	PTKc_Csk_like
cd14101	155-405	STKc_PIM2
cd06649	148-357	PKc_MEK2
cd14222	156-343	STKc_LIMK2
cd14019	148-408	STKc_Cdc7
cd05074	149-391	PTKc_Tyro3
cd14062	156-351	STKc_Raf
cd07848	148-355	STKc_CDKL5
cd08229	146-391	STKc_Nek7
cd14065	156-348	PKc_LIMK_like
cd14134	148-408	PKc_CLK
cd05038	149-342	PTKc_Jak_rpt2
cd06619	149-407	PKc_MKK5
cd07871	152-408	STKc_PCTAIRE3
cd13986	150-405	STKc_16
cd14100	155-391	STKc_PIM1
cd14109	154-408	PK_Unc-89_rpt1
cd14048	147-405	STKc_EIF2AK3_PERK
cd06607	150-407	STKc_TAO
cd07844	152-408	STKc_PCTAIRE_like
cd13976	240-408	PK_TRB
cd07873	152-408	STKc_PCTAIRE1
cd14154	156-347	STKc_LIMK
cd07858	154-409	STKc_TEY_MAPK
cd14060	157-349	STKc_MLTK
cd07880	153-408	STKc_p38gamma
cd14033	198-408	STKc_WNK4
cd07856	146-409	STKc_Sty1_Hog1
cd14221	156-347	STKc_LIMK1
cd14151	156-391	STKc_B-Raf
cd14031	198-409	STKc_WNK3
cd05059	149-375	PTKc_Tec_like
cd06639	137-351	STKc_myosinIIIB_N
cd07852	260-409	STKc_MAPK15-like
cd05082	145-349	PTKc_Csk
cd06633	150-407	STKc_TAO3
cd07872	152-408	STKc_PCTAIRE2
cd06617	257-408	PKc_MKK3_6
cd13988	156-349	STKc_TBK1
cd14108	156-408	STKc_SPEG_rpt1
cd07857	150-401	STKc_MPK1
cd14205	152-342	PTKc_Jak2_rpt2
smart00133	409-476	S_TK_X
cl11395	409-476	Pkinase_C superfamily
cd07843	149-408	STKc_CDC2L1
cd14063	149-403	PK_KSR
cd06616	143-418	PKc_MKK4
cd14068	155-391	STKc_LRRK2
cd07870	153-408	STKc_PFTAIRE2
cd07879	153-408	STKc_p38delta
cd06635	150-353	STKc_TAO1
cd14149	145-349	STKc_C-Raf
cd13982	256-408	STKc_IRE1
cd07861	149-408	STKc_CDK1_euk
cd14226	147-391	PKc_DYRK1
cd05045	154-391	PTKc_RET
cd14064	156-349	PKc_TNNI3K
cd14056	154-344	STKc_TGFbR_I
cd14156	156-348	PKc_LIMK_like_unk
cd14032	198-409	STKc_WNK2_like
cd05079	156-343	PTKc_Jak1_rpt2
cd06634	150-353	STKc_TAO2
cd07869	148-349	STKc_PFTAIRE1
cd05080	152-343	PTKc_Tyk2_rpt2
cd07854	153-409	STKc_MAPK4_6
cd05083	154-391	PTKc_Chk
cd13998	155-367	STKc_TGFbR-like
cd05148	149-391	PTKc_Srm_Brk
cd14212	153-381	PKc_YAK1
cd07849	149-409	STKc_ERK1_2_like
cd13991	149-391	STKc_NIK
cd14132	146-408	STKc_CK2_alpha
cd07837	148-408	STKc_CdkB_plant
cd13975	256-354	PKc_Dusty
cd14224	150-345	PKc_DYRK2_3
cd14026	153-349	STKc_RIP2
cd14030	187-408	STKc_WNK1
cd07853	149-449	STKc_NLK
cd07859	150-411	STKc_TDY_MAPK
cd05057	145-349	PTKc_EGFR_like
cd14016	153-362	STKc_CK1
smart00233	6-108	PH
cd07839	150-408	STKc_CDK5
cd05113	149-349	PTKc_Btk_Bmx
cd05041	156-361	PTKc_Fes_like
pfam00169	6-104	PH
cd05085	154-341	PTKc_Fer
cd07862	149-373	STKc_CDK6
cd05032	145-362	PTKc_InsR_like
cd07864	147-407	STKc_CDK12
cd13995	158-405	STKc_MAP3K8
cd14067	156-348	STKc_LRRK1
cd13968	156-294	PKc_like
cd05114	148-361	PTKc_Tec_Rlk
cd05035	154-391	PTKc_TAM
cd14229	150-381	STKc_HIPK3
cd07878	150-354	STKc_p38beta
cd05112	148-361	PTKc_Itk
cd14025	154-349	STKc_RIP4_like
cd05116	156-393	PTKc_Syk
cd14011	257-408	PK_SCY1_like
cd07842	150-408	STKc_CDK8_like
cd14027	156-391	STKc_RIP1
cd13992	173-370	PK_GC
cd05060	156-349	PTKc_Syk_like
cd14158	155-366	STKc_IRAK4
cd14214	150-391	PKc_CLK3
cd05043	138-357	PTK_Ryk
cd13276	8-103	PH_AtPH1
cd05084	156-391	PTKc_Fes
cd14112	150-407	STKc_Unc-89_rpt2
cd14227	148-382	STKc_HIPK2
cd07863	149-408	STKc_CDK4
cd14664	156-349	STK_BAK1_like
cd14155	156-348	PKc_TESK
cd14152	149-391	STKc_KSR1
cd05056	144-349	PTKc_FAK
cd05095	141-359	PTKc_DDR2
cd07850	260-424	STKc_JNK
cd05092	156-392	PTKc_TrkA
cd07876	248-424	STKc_JNK2
cd14225	150-355	PKc_DYRK4
cd05047	155-391	PTKc_Tie
cd14159	156-365	STKc_IRAK1
cd14228	148-382	STKc_HIPK1
cd05101	141-361	PTKc_FGFR2
cd14055	154-343	STKc_TGFbR2_like
cd05048	144-361	PTKc_Ror
cd05097	141-359	PTKc_DDR_like
cd14211	150-350	STKc_HIPK
cd08216	151-408	PK_STRAD
cd05100	139-361	PTKc_FGFR3
cd14036	154-357	STKc_GAK
cd05075	154-361	PTKc_Axl
cd14213	150-386	PKc_CLK1_4
cd05063	154-376	PTKc_EphR_A2
cd05040	154-342	PTKc_Ack_like
cd07875	248-427	STKc_JNK1
cd14206	152-365	PTKc_Aatyk3
cd05115	156-349	PTKc_Zap-70
cd14204	154-391	PTKc_Mer
cd05098	141-361	PTKc_FGFR1
cd01252	8-106	PH_GRP1-like
cd13282	8-109	PH1_PLEKHH1_PLEKHH2
cd13255	1-113	PH_TAAP2-like
cd05072	141-391	PTKc_Lyn
cd14001	152-391	PKc_TOPK
cd05089	149-391	PTKc_Tie1
cd05050	148-357	PTKc_Musk
pfam00433	428-477	Pkinase_C
cd05067	151-349	PTKc_Lck_Blk
cd14207	151-391	PTKc_VEGFR1
cd14037	143-391	STKc_NAK_like
cd14136	156-408	STKc_SRPK
cd05065	154-353	PTKc_EphR_B
cd13977	223-356	STKc_PDIK1L
cd05099	141-361	PTKc_FGFR4
cd05058	154-350	PTKc_Met_Ron
cd05053	141-391	PTKc_FGFR
cd14142	153-342	STKc_ACVR1_ALK1
cd07874	245-424	STKc_JNK3
cd05088	148-391	PTKc_Tie2
cd14215	150-391	PKc_CLK2
cd05087	152-381	PTKc_Aatyk1
cd05033	154-353	PTKc_EphR
cd05108	149-349	PTKc_EGFR
cd05055	148-342	PTKc_PDGFR
cd05046	153-355	PTK_CCK4
cd05090	198-391	PTKc_Ror1
cd05103	253-391	PTKc_VEGFR2
cd05066	154-373	PTKc_EphR_A
cd14053	154-367	STKc_ACVR2
cd05093	156-392	PTKc_TrkB
cd05034	154-349	PTKc_Src_like
cd05054	154-391	PTKc_VEGFR
cd14153	149-357	PK_KSR2
cd13288	8-116	PH_Ses
cd05049	156-392	PTKc_Trk
cd00821	8-103	PH
cd13263	6-107	PH_RhoGap25-like
cd13215	5-104	PH-GRAM1_AGT26
smart00220	150-408	S_TKc
pfam00069	150-408	Pkinase
PTZ00263	147-455	PTZ00263
PTZ00426	140-439	PTZ00426
COG0515	149-435	SPS1
PHA03390	159-408	pk1
pfam07714	150-391	Pkinase_Tyr
smart00221	153-361	STYKc
PTZ00267	177-391	PTZ00267
smart00219	153-361	TyrKc
PLN00034	122-410	PLN00034
PTZ00283	154-391	PTZ00283
PTZ00266	147-391	PTZ00266
PRK13184	147-405	pknD
PTZ00024	154-408	PTZ00024
PHA03209	116-343	PHA03209
PHA03212	114-359	PHA03212
PTZ00036	111-392	PTZ00036
PLN00009	147-408	PLN00009
PTZ00284	145-390	PTZ00284
PHA03207	124-350	PHA03207
TIGR03903	172-391	TOMM_kin_cyc
PHA03211	185-341	PHA03211
PHA03210	256-343	PHA03210

Ontology Information

   

HPRD ID	1133
Molecular Class	Serine/threonine kinase
Molecular Function	Transcription regulator activity (GO:0030528)
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)

SNP Information

View SNP Geneview Report