Search results:


General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
EVPL 2125 Envoplakin  17EVPK 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20089989   2010Cell line : -

Source : VU University Medical Center, Amsterdam, The Netherlands.

Sample Type : CRC tumor and Normal tissue

No. of Sample : -

Stage : -

Biochemical isolation to nano-LC-MS/MS analysis.Up-regulation-This genes are differenitially expressed between colorectal adenoma and Colorectal cancer tissue.

CRC tissue was collected at the VU University Medical Center, Amsterdam, The Netherlands.


Gene Details



Chromosome: 17; NC_000017.10 (74002927..74023507, complement)

View Larger Image
   
Gene Type protein coding
Gene Family -
Description -  
Chromosome 17
Location 17q25
Start 76006845  
End 76027452  
Strand -  
Gene Sequence

   Download   Select all

Length 20608  
OMIM ID 601590   
HGNC ID HGNC:3503   
Unigene ID Hs.500635    
Ensembl ID ENSG00000167880   
PharmGKB ID -   

mRNA Information


mRNA ID XM_011524516.1
Exon join(1..352,3333..3432,3799..3953,4035..4161,4915..5040, 5226..5264,5425..5586,5672..5779,5890..5985,7800..7925, 8393..8539,8853..9007,9195..9358,9542..9714,11825..12003, 12088..12226,12344..12537,12877..13027,15364..15447, 15571..15681,15785..15877,16910..20608)  
mRNA Sequence

   Download   Select all

Length 6587  



CDS Information


   
Locationjoin(255..352,3333..3432,3799..3953,4035..4161,4915..5040, 5226..5264,5425..5586,5672..5779,5890..5985,7800..7925, 8393..8539,8853..9007,9195..9292,9542..9714,11825..12003, 12088..12226,12344..12537,12877..13027,15364..15447, 15571..15681,15785..15877,16910..20350)
CDS Sequence

   Download   Select all

CCDS ID CCDS11737.1



Protein Information


      
Protein IDNP_001979.2
Protein NameEnvoplakin
Molecular Wt. (Da)231474
Protein Sequence

   Download   Select all

Length 2033  
Uniprot IDP32302
Ensembl Protein ID ENSP00000292174  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation1392
SPhosphorylation2025
SPhosphorylation18
SPhosphorylation219
SPhosphorylation1263
SPhosphorylation1799
SPhosphorylation1813
SPhosphorylation1916
SPhosphorylation2006
YPhosphorylation2018
SPhosphorylation227
TPhosphorylation230
YPhosphorylation360

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                                                                                                                                      
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
1475CSTA1697NP_005204.1in vivo8999895   
1832DSP513NP_004406.2in vivo8999895   
3713IVL931NP_005538.2in vivo8999895   
3848KRT1763NP_006112.3in vivo8999895   
3849KRT22560NP_000414.2in vivo8999895   
3852KRT51010NP_000415.2in vivo8999895   
3858KRT101021NP_000412.3in vivo8999895   
4014LOR1070BAA25794.1in vivo8999895   
6700SPRR2A1649NP_005979.1in vivo8999895   
6707SPRR31652NP_005407.1in vivo8999895   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam006811856-1900  Plectin
cl233641856-1900  Plectin superfamily
cd00176228-415  SPEC
cl02488228-415  SPEC superfamily
smart002501894-1931  PLEC
cl233491894-1931  PLEC superfamily
pfam006811932-1976  Plectin
cl233641932-1976  Plectin superfamily
smart002501856-1889  PLEC
cl233491856-1889  PLEC superfamily
cd00176156-330  SPEC
smart00150237-330  SPEC
pfam006811688-1720  Plectin
cl233641688-1720  Plectin superfamily
smart002501818-1855  PLEC
cl233491818-1855  PLEC superfamily
smart002501932-1969  PLEC
cl233491932-1969  PLEC superfamily
pfam006811894-1929  Plectin
cl233641894-1929  Plectin superfamily
pfam006811827-1862  Plectin
cl233641827-1862  Plectin superfamily
smart002501688-1713  PLEC
cl233491688-1713  PLEC superfamily
pfam10174908-1678  Cast
COG1196912-1676  Smc
TIGR02168678-1538  SMC_prok_B
COG1196892-1675  Smc
TIGR02169908-1702  SMC_prok_A
TIGR02168946-1690  SMC_prok_B
PTZ00121879-1662  PTZ00121
TIGR02168912-1645  SMC_prok_B
COG1196668-1452  Smc
COG1196910-1359  Smc
TIGR02169912-1537  SMC_prok_A
pfam13514879-1650  AAA_27
COG11961192-1604  Smc
pfam02463917-1688  SMC_N
PRK039181038-1545  PRK03918
COG04191097-1690  SbcC
TIGR02168795-1127  SMC_prok_B
TIGR02168723-1495  SMC_prok_B
PRK03918914-1470  PRK03918
COG0419880-1530  SbcC
COG0419786-1333  SbcC
PTZ001211087-1679  PTZ00121
COG11961297-1684  Smc
TIGR02168912-1686  SMC_prok_B
PTZ00121850-1402  PTZ00121
TIGR02169668-1451  SMC_prok_A
PRK039181191-1666  PRK03918
COG11961401-1690  Smc
TIGR00618666-1295  sbcc
TIGR006181109-1689  sbcc
PRK03918879-1422  PRK03918
TIGR02169903-1245  SMC_prok_A
pfam121281147-1678  DUF3584
pfam12128912-1684  DUF3584
PRK039181033-1530  PRK03918
pfam04094834-1124  DUF390
PTZ00121786-1059  PTZ00121
COG15791085-1275  COG1579
pfam056671184-1356  DUF812
COG49421150-1365  EnvC
pfam09726998-1220  Macoilin
PRK02224969-1464  PRK02224
pfam024631178-1530  SMC_N
pfam024631346-1739  SMC_N
pfam12128667-1335  DUF3584
TIGR042111248-1355  SH3_and_anchor


Ontology Information


   
HPRD ID3367
Molecular ClassStructural protein
Molecular FunctionG-protein coupled receptor activity (GO:0004930)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO