CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
19404924	2009	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	real time RT-PCR,Methylation-specific PCR	Methylation	-	Promoter methylations of the studied genes could be explored as promising biomarkers for new diagnostic, prognostic and therapeutic targets of colorectal cancer.

Gene Details

NC_000001.10 (27938800..27961727, complement)
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Gene Type	protein coding
Gene Family	SH2 domain containing
Description	This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Chromosome	1
Location	1p36.2-p36
Start	27938800
End	27961727
Strand	-
Gene Sequence	Download Select all
Length	22928
OMIM ID	164940
HGNC ID	HGNC:3697
Unigene ID	Hs.1422
Ensembl ID	ENSG00000000938
PharmGKB ID	PA28135

mRNA Information

mRNA ID	XM_011541010.1
Exon	join(1..117,10411..10473,11633..11871,12418..12520, 13905..14003,18266..18369,18556..18705,19718..19873, 19949..20128,20636..20712,20979..21132,22212..22343, 22440..23273)
mRNA Sequence	Download Select all
Length	2408

CDS Information

Location	194..1783
CDS Sequence	Download Select all
CCDS ID	CCDS305.1

Protein Information

Protein ID	XP_011539312.1
Protein Name	FGR proto-oncogene, Src family tyrosine kinase
Molecular Wt. (Da)	59348
Protein Sequence	Download Select all
Length	529
Uniprot ID	P62820
Ensembl Protein ID	ENSP00000381540

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Phosphorylation	412
Y	Phosphorylation	523
Y	Phosphorylation	34;-
Y	Phosphorylation	28;-
Y	Phosphorylation	34;-
Y	Phosphorylation	28;-
Y	Phosphorylation	34;-
Y	Phosphorylation	28;-
Y	Phosphorylation	208;-
Y	Phosphorylation	208;-
Y	Phosphorylation	208;-
Y	Phosphorylation	412;-
Y	Phosphorylation	412;-

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
408	ARRB1	146	NP_004032.2	in vivo	10973280
1796	DOK1	4228	NP_001372.1	in vitro	11071635
3059	HCLS1	3199	NP_005326.2	in vitro;in vivo	10066823
6622	SNCA	1227	NP_000336.1	in vitro;in vivo	120 967 131 174 462 000 000 000
6714	SRC	1819	NP_005408.1	in vitro	124 686 451 238 781 000 000 000 000 000
10971	YWHAQ	886	NP_006817.1	in vitro	10066823

Pathway Information

Pathway Name	Pathway ID
Chemokine signaling pathway	hsa04062
Epstein-Barr virus infection	hsa05169

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd10367	140-240	SH2_Src_Fgr
cl15255	140-240	SH2 superfamily
cd14203	267-514	PTKc_Src_Fyn_like
cl21453	267-514	PKc_like superfamily
cd05034	267-513	PTKc_Src_like
cd05069	250-527	PTKc_Yes
cd05068	254-518	PTKc_Frk_like
cd05070	253-526	PTKc_Fyn
cd05071	253-527	PTKc_Src
cd05067	256-518	PTKc_Lck_Blk
cd05072	255-524	PTKc_Lyn
cd05073	253-515	PTKc_Hck
cd05148	256-515	PTKc_Srm_Brk
cd00192	267-513	PTKc
cd05052	256-516	PTKc_Abl
cd05059	258-512	PTKc_Tec_like
cd05039	256-513	PTKc_Csk_like
cd05112	258-508	PTKc_Itk
cd05041	267-512	PTKc_Fes_like
cd05033	258-515	PTKc_EphR
cd05082	256-514	PTKc_Csk
cd05113	258-513	PTKc_Btk_Bmx
cd05114	258-514	PTKc_Tec_Rlk
cd05032	256-514	PTKc_InsR_like
cd05060	267-515	PTKc_Syk_like
cd05083	256-513	PTKc_Chk
cd13999	269-512	STKc_MAP3K-like
cd05053	255-513	PTKc_FGFR
cd05085	269-512	PTKc_Fer
cd05044	269-514	PTKc_c-ros
cd05056	256-514	PTKc_FAK
cd05063	257-513	PTKc_EphR_A2
cd05066	258-513	PTKc_EphR_A
cd05040	268-514	PTKc_Ack_like
cd05065	258-513	PTKc_EphR_B
cd05084	268-512	PTKc_Fes
cd05057	269-508	PTKc_EGFR_like
cd09933	140-240	SH2_Src_family
cd05036	257-508	PTKc_ALK_LTK
cd05051	257-512	PTKc_DDR
cd05048	257-512	PTKc_Ror
cd05099	256-523	PTKc_FGFR4
cd05055	255-514	PTKc_PDGFR
cd05049	257-506	PTKc_Trk
cd10418	140-240	SH2_Src_Fyn_isoform_a_like
cd05064	257-512	PTKc_EphR_A10
cd05092	258-513	PTKc_TrkA
cd10368	140-240	SH2_Src_Fyn
cd05058	267-518	PTKc_Met_Ron
cd05050	257-513	PTKc_Musk
cd05061	256-524	PTKc_InsR
cd05038	263-509	PTKc_Jak_rpt2
cd05098	256-508	PTKc_FGFR1
cd05100	252-528	PTKc_FGFR3
cd05116	269-516	PTKc_Syk
cd05045	262-513	PTKc_RET
cd05109	267-508	PTKc_HER2
cd14014	264-504	STKc_PknB_like
cd05115	266-518	PTKc_Zap-70
cd05101	256-517	PTKc_FGFR2
cd05046	258-514	PTK_CCK4
cd05075	263-513	PTKc_Axl
cd05093	258-523	PTKc_TrkB
cd00180	269-512	PKc
cd05108	267-508	PTKc_EGFR
cd05110	269-510	PTKc_HER4
cd05062	256-514	PTKc_IGF-1R
cd10419	141-234	SH2_Src_Fyn_isoform_b_like
cd05074	258-513	PTKc_Tyro3
cd05095	257-514	PTKc_DDR2
cd05035	263-514	PTKc_TAM
cd05090	257-515	PTKc_Ror1
cd05091	257-515	PTKc_Ror2
cd05094	258-512	PTKc_TrkC
cd05054	256-514	PTKc_VEGFR
cd05097	257-512	PTKc_DDR_like
cd05106	254-513	PTKc_CSF-1R
cd10366	140-237	SH2_Src_Yes
cd10363	140-241	SH2_Src_HCK
cd05043	258-517	PTK_Ryk
cd10365	140-237	SH2_Src_Src
cd14204	258-513	PTKc_Mer
cd05096	257-512	PTKc_DDR1
cd10362	140-240	SH2_Src_Lck
cd05047	301-505	PTKc_Tie
cd05111	269-510	PTK_HER3
cd10364	140-240	SH2_Src_Lyn
cd05089	256-505	PTKc_Tie1
cd05079	267-508	PTKc_Jak1_rpt2
cd14066	269-513	STKc_IRAK
cd06606	262-504	STKc_MAPKKK
cd05080	267-515	PTKc_Tyk2_rpt2
cd05104	256-513	PTKc_Kit
cd05105	256-513	PTKc_PDGFR_alpha
cd14062	269-513	STKc_Raf
cd05107	255-517	PTKc_PDGFR_beta
cd14205	267-514	PTKc_Jak2_rpt2
cd05102	256-514	PTKc_VEGFR3
cd10371	140-240	SH2_Src_Blk
cd05081	269-513	PTKc_Jak3_rpt2
cd13978	269-505	STKc_RIP
cd05088	261-505	PTKc_Tie2
cd14207	256-514	PTKc_VEGFR1
cd14151	254-513	STKc_B-Raf
cd05103	256-514	PTKc_VEGFR2
cd14146	269-505	STKc_MLK4
cd14060	270-513	STKc_MLTK
cd05087	267-512	PTKc_Aatyk1
cd10370	140-240	SH2_Src_Src42
cd14149	256-513	STKc_C-Raf
cd14058	269-514	STKc_TAK1
cd14221	269-514	STKc_LIMK1
cd06627	264-508	STKc_Cdc7_like
cd14061	269-506	STKc_MLK
cd14150	263-513	STKc_A-Raf
cd14145	257-505	STKc_MLK1
cd05122	264-508	PKc_STE
cd14059	269-513	STKc_MAP3K12_13
cd14154	269-513	STKc_LIMK
pfam00017	144-226	SH2
cd14147	263-513	STKc_MLK3
cd10369	140-240	SH2_Src_Frk
cd10344	129-234	SH2_SLAP
cd05042	267-512	PTKc_Aatyk
cd14065	269-512	PKc_LIMK_like
cd14148	269-514	STKc_MLK2
cd14003	264-504	STKc_AMPK-like
cd12007	80-137	SH3_Yes
cl17036	80-137	SH3 superfamily
cd05118	267-504	STKc_CMGC
cd12006	80-135	SH3_Fyn_Yrk
cd14009	269-506	STKc_ATG1_ULK_like
smart00252	142-232	SH2
cd14064	269-514	PKc_TNNI3K
cd07840	269-477	STKc_CDK9_like
cd14027	269-505	STKc_RIP1
cd05086	267-512	PTKc_Aatyk2
cd14158	267-453	STKc_IRAK4
cd13992	288-512	PK_GC
cd05117	264-504	STKc_CAMK
cd14081	265-506	STKc_BRSK1_2
cd06605	269-508	PKc_MAPKK
cd14042	279-512	PK_GC-A_B
cd14008	269-504	STKc_LKB1_CaMKK
cd14206	267-509	PTKc_Aatyk3
cd07830	264-516	STKc_MAK_like
cd11845	81-132	SH3_Src_like
cd14073	265-506	STKc_NUAK
cd14080	264-506	STKc_TSSK-like
cd14222	269-513	STKc_LIMK2
cd08215	264-504	STKc_Nek
cd06614	268-508	STKc_PAK
cd06610	287-508	STKc_OSR1_SPAK
cd05037	263-505	PTK_Jak_rpt1
cd14063	263-513	PK_KSR
cd14664	269-456	STK_BAK1_like
cd06628	269-504	STKc_Byr2_like
cd06632	269-508	STKc_MEKK1_plant
cd06626	267-509	STKc_MEKK4
cd14162	263-474	STKc_TSSK4-like
cd14119	269-510	STKc_LKB1
cd14007	267-506	STKc_Aurora
cd14045	280-512	PK_GC_unk
cd12008	82-135	SH3_Src
cd13985	262-509	STKc_GAK_like
cd06612	269-463	STKc_MST1_2
cd07866	268-454	STKc_BUR1
cd14071	265-474	STKc_SIK
cd08222	265-504	STKc_Nek11
cd13979	262-504	STKc_Mos
cd13997	266-508	PKc_Wee1_like
cd14056	268-504	STKc_TGFbR_I
cd14099	267-516	STKc_PLK
cd14156	269-514	PKc_LIMK_like_unk
cd14012	306-510	PK_eIF2AK_GCN2_rpt1
cd06623	265-510	PKc_MAPKK_plant_like
cd14050	264-508	PKc_Myt1
cd14098	267-504	STKc_Rad53_Cds1
cd14072	265-478	STKc_MARK
cd05581	267-504	STKc_PDK1
cd05123	269-502	STKc_AGC
cd06625	267-511	STKc_MEKK3_like
cd08529	268-510	STKc_FA2-like
cd08225	267-504	STKc_Nek5
cd14075	269-510	STKc_NIM1
cd14079	264-506	STKc_AMPK_alpha
cd00173	143-226	SH2
cd06609	264-508	STKc_MST3_like
cd14006	269-474	STKc_MLCK-like
cd14043	275-506	PK_GC-2D
cd07829	267-454	STKc_CDK_like
cd09935	144-240	SH2_ABL
cd14053	272-454	STKc_ACVR2
cd14069	264-510	STKc_Chk1
cd07841	264-519	STKc_CDK7
cd06607	267-508	STKc_TAO
cd06629	269-510	STKc_Bck1_like
cd14025	267-506	STKc_RIP4_like
cd09941	144-227	SH2_Grb2_like
cd07833	268-516	STKc_CDKL
cd14121	268-506	STKc_ULK3
cd14057	275-513	PK_ILK
cd07832	268-512	STKc_CCRK
cd14155	269-513	PKc_TESK
cd07834	264-527	STKc_MAPK
cd14078	265-508	STKc_MELK
cd14026	267-505	STKc_RIP2
cd07864	269-484	STKc_CDK12
cd14068	269-510	STKc_LRRK2
cd06640	268-508	STKc_MST4
cd14137	262-463	STKc_GSK3
cd14161	269-506	STKc_NUAK2
cd07877	251-522	STKc_p38alpha
cd13983	265-516	STKc_WNK
cd07843	288-471	STKc_CDC2L1
cd06642	268-504	STKc_STK25
cd14663	265-506	STKc_SnRK3
cd14190	259-474	STKc_MLCK2
cd08220	266-504	STKc_Nek8
cd13982	266-504	STKc_IRE1
cd08530	264-504	STKc_CNK2-like
cd06611	254-504	STKc_SLK_like
pfam00018	83-130	SH3_1
cd06619	323-508	PKc_MKK5
cd06613	268-451	STKc_MAP4K3_like
cd14165	287-478	STKc_TSSK1_2-like
cd06620	279-520	PKc_Byr1_like
cd14052	264-450	PTKc_Wee1_fungi
cd06621	263-460	PKc_Pek1_like
cd13998	270-504	STKc_TGFbR-like
cd13994	269-516	STKc_HAL4_like
cd06653	265-508	STKc_MEKK3_like_u1
cd06641	268-508	STKc_MST3
cd14074	265-506	STKc_SNRK
cd14070	267-503	STKc_HUNK
cd06633	269-473	STKc_TAO3
cd07845	268-473	STKc_CDK10
cd10360	144-226	SH2_Srm
cd14144	267-491	STKc_BMPR1
cd06617	285-509	PKc_MKK3_6
cd14193	262-471	STKc_MLCK4
cd06631	269-510	STKc_YSK4
cd13996	269-504	STKc_EIF2AK
cd07860	268-461	STKc_CDK2_3
cd06644	254-525	STKc_STK10
cd14142	262-451	STKc_ACVR1_ALK1
cd12009	83-135	SH3_Blk
smart00326	78-134	SH3
cd14159	269-458	STKc_IRAK1
cd05580	261-453	STKc_PKA_like
cd05619	261-481	STKc_nPKC_theta
cd14186	269-506	STKc_PLK4
cd07870	261-522	STKc_PFTAIRE2
cd14084	264-506	STKc_Chk2
cd08218	267-504	STKc_Nek1
cd14220	267-462	STKc_BMPR1a
cd14000	269-514	STKc_LRRK
cd07865	268-462	STKc_CDK9
cd06650	304-525	PKc_MEK1
cd14164	264-470	STKc_TSSK6-like
cd08224	264-508	STKc_Nek6_7
cd14133	269-504	PKc_DYRK_like
cd06618	248-518	PKc_MKK7
cd14044	303-517	PK_GC-C
cd08223	267-504	STKc_Nek4
cd07878	251-480	STKc_p38beta
cd08219	267-504	STKc_Nek3
cd12004	81-137	SH3_Lyn
cd06634	267-508	STKc_TAO2
cd07856	269-463	STKc_Sty1_Hog1
cd14010	304-486	STKc_ULK4
cd14039	269-502	STKc_IKK_alpha
cd05572	269-461	STKc_cGK
cd05578	267-502	STKc_Yank1
cd06635	267-508	STKc_TAO1
cd10341	140-229	SH2_N-SH2_PLC_gamma_like
cd05077	287-505	PTK_Jak1_rpt1
cd14143	268-451	STKc_TGFbR1_ACVR1b_ACVR1c
cd14103	269-474	STKc_MLCK
cd06615	304-467	PKc_MEK
cd09937	144-240	SH2_csk_like
cd07836	268-505	STKc_Pho85
cd14002	270-459	STKc_STK36
cd14114	269-472	STKc_Twitchin_like
cd09938	144-241	SH2_N-SH2_Zap70_Syk_like
cd07851	251-463	STKc_p38
cd10354	143-226	SH2_Cterm_RasGAP
cd00174	82-132	SH3
cd08216	301-480	PK_STRAD
cd14054	269-504	STKc_BMPR2_AMHR2
cd06649	304-486	PKc_MEK2
cd06622	318-508	PKc_PBS2_like
cd08217	268-508	STKc_Nek2
cd14046	268-510	STKc_EIF2AK4_GCN2_rpt2
cd07880	253-471	STKc_p38gamma
cd08229	240-510	STKc_Nek7
cd14038	268-504	STKc_IKK_beta
cd06652	265-508	STKc_MEKK2
cd06651	269-508	STKc_MEKK3
cd13987	269-459	STKc_SBK1
cd05582	269-471	STKc_RSK_N
cd14191	265-471	STKc_MLCK1
cd07846	298-504	STKc_CDKL2_3
cd14194	306-471	STKc_DAPK1
cd14188	269-516	STKc_PLK2
cd07873	268-525	STKc_PCTAIRE1
cd14201	269-459	STKc_ULK2
cd05620	269-478	STKc_nPKC_delta
cd07871	268-468	STKc_PCTAIRE3
cd06643	253-473	STKc_SLK
cd14076	265-459	STKc_Kin4
cd14105	306-474	STKc_DAPK
cd07852	265-463	STKc_MAPK15-like
cd14120	269-506	STKc_ULK1_2-like
cd13986	264-514	STKc_16
cd08226	259-481	PK_STRAD_beta
cd14097	264-474	STKc_STK33
cd07839	300-461	STKc_CDK5
cd07853	265-457	STKc_NLK
cd07849	269-461	STKc_ERK1_2_like
cd14209	267-478	STKc_PKA
cd14096	264-476	STKc_RCK1-like
cd14185	267-504	STKc_DCKL3
cd07859	304-525	STKc_TDY_MAPK
cd14202	256-467	STKc_ULK1
cd05076	287-505	PTK_Tyk2_rpt1
cd07869	268-473	STKc_PFTAIRE1
cd08228	261-511	STKc_Nek6
cd09934	137-242	SH2_Tec_family
cd06637	269-468	STKc_TNIK
cd07854	267-471	STKc_MAPK4_6
cd14055	268-429	STKc_TGFbR2_like
cd06638	254-451	STKc_myosinIIIA_N
cd14219	263-451	STKc_BMPR1b
cd14160	269-457	PK_IRAK3
cd05616	269-471	STKc_cPKC_beta
cd05579	272-503	STKc_MAST_like
cd10398	143-240	SH2_Tec_Txk
cd14131	301-511	PKc_Mps1
cd06647	268-463	STKc_PAK_I
cd06616	256-521	PKc_MKK4
cd14187	259-518	STKc_PLK1
cd07855	267-463	STKc_ERK5
cd14004	267-508	STKc_PASK
cd14192	269-471	STKc_MLCK3
cd06659	268-459	STKc_PAK6
cd14095	306-480	STKc_DCKL
cd13995	272-504	STKc_MAP3K8
cd12005	81-134	SH3_Lck
cd10402	144-241	SH2_C-SH2_Zap70
cd06624	269-459	STKc_ASK
cd05632	267-473	STKc_GRK5
cd07861	268-454	STKc_CDK1_euk
cd09940	143-230	SH2_Vav_family
cd13990	304-470	STKc_TLK
cd05590	267-471	STKc_nPKC_eta
cd14011	306-514	PK_SCY1_like
cd09931	144-226	SH2_C-SH2_SHP_like
cd05630	267-473	STKc_GRK6
cd14163	287-508	STKc_TSSK3-like
cd07838	268-451	STKc_CDK4_6_like
cd05615	269-471	STKc_cPKC_alpha
cd06608	270-451	STKc_myosinIII_N_like
cd14033	269-516	STKc_WNK4
cd13989	269-473	STKc_IKK
cd06917	264-461	STKc_NAK1_like
cd06655	260-468	STKc_PAK2
cd06636	269-468	STKc_MAP4K4_6_N
cd14132	254-454	STKc_CK2_alpha
cd14208	263-505	PTK_Jak3_rpt1
cd05570	269-471	STKc_PKC
cd13975	265-514	PKc_Dusty
cd10348	143-233	SH2_Cterm_shark_like
cd09943	142-227	SH2_Nck_family
cd14077	283-474	STKc_Kin1_2
cd14196	306-471	STKc_DAPK2
cd11850	81-135	SH3_Abl
cd11772	82-135	SH3_OSTF1
cd11840	83-135	SH3_Intersectin_5
cd05589	269-471	STKc_PKN
cd06630	269-504	STKc_MEKK1
cd07847	301-461	STKc_CDKL1_4
cd07857	264-458	STKc_MPK1
cd14189	267-516	STKc_PLK3
cd05577	269-473	STKc_GRK
cd14036	265-515	STKc_GAK
cd06648	260-459	STKc_PAK_II
cd05573	267-466	STKc_ROCK_NDR_like
cd05592	269-471	STKc_nPKC_theta_like
cd06658	268-459	STKc_PAK5
cd07835	300-461	STKc_CDK1_CdkB_like
cd05587	269-471	STKc_cPKC
cd07844	288-472	STKc_PCTAIRE_like
cd14136	266-453	STKc_SRPK
cd08528	269-503	STKc_Nek10
cd10361	137-228	SH2_Fps_family
cd05622	242-459	STKc_ROCK1
cd06646	265-451	STKc_MAP4K5
cd14175	285-474	STKc_RSK1_C
cd07872	263-461	STKc_PCTAIRE2
cd14166	260-476	STKc_CaMKI_gamma
cd05078	266-508	PTK_Jak2_rpt1
pfam14604	84-134	SH3_9
cd14005	269-506	STKc_PIM
cd07879	251-480	STKc_p38delta
cd14152	263-513	STKc_KSR1
cd10401	144-241	SH2_C-SH2_Syk_like
cd14199	291-465	STKc_CaMKK2
cd14091	269-475	STKc_RSK_C
cd07850	287-522	STKc_JNK
cd07863	269-454	STKc_CDK4
cd14197	317-473	STKc_DRAK1
cd14135	269-468	STKc_PRP4
cd13993	262-460	STKc_Pat1_like
cd14195	306-471	STKc_DAPK3
cd14107	269-504	STKc_obscurin_rpt1
cd07842	270-453	STKc_CDK8_like
cd14179	306-474	STKc_MSK1_C
cd07858	287-461	STKc_TEY_MAPK
cd14113	253-459	STKc_Trio_C
cd05601	269-463	STKc_CRIK
cd06656	268-468	STKc_PAK3
cd13988	269-471	STKc_TBK1
cd14184	306-510	STKc_DCKL2
cd06654	268-468	STKc_PAK1
cd07875	288-505	STKc_JNK1
cd14109	302-504	PK_Unc-89_rpt1
cd10358	141-226	SH2_PTK6_Brk
cd11996	83-133	SH3_Intersectin2_5
cd05631	267-473	STKc_GRK4
cd14093	302-412	STKc_PhKG
cd14178	285-474	STKc_RSK3_C
cd14198	304-506	STKc_DRAK2
cd08221	304-508	STKc_Nek9
cd11770	81-135	SH3_Nephrocystin
cd05603	269-483	STKc_SGK2
cd09942	137-226	SH2_nSH2_p85_like
cd14047	268-508	STKc_EIF2AK2_PKR
cd14210	269-469	PKc_DYRK
cd10408	143-226	SH2_Nck1
cd13991	263-443	STKc_NIK
cd14001	305-453	PKc_TOPK
cd14177	289-474	STKc_RSK4_C
cd14067	303-503	STKc_LRRK1
cd14153	269-513	PK_KSR2
cd14116	267-473	STKc_Aurora-A
cd11855	84-134	SH3_Sho1p
cd14019	264-459	STKc_Cdc7
cd10340	144-228	SH2_N-SH2_SHP_like
cd09932	142-227	SH2_C-SH2_PLC_gamma_like
cd12011	82-136	SH3_SLAP2
cd05611	272-474	STKc_Rim15_like
cd14176	289-474	STKc_RSK2_C
cd07874	288-505	STKc_JNK3
cd05605	267-473	STKc_GRK4_like
cd14017	267-513	STKc_TTBK
cd14092	306-466	STKc_MSK_C
cd14031	269-474	STKc_WNK3
cd05621	269-459	STKc_ROCK2
cd10347	144-226	SH2_Nterm_shark_like
cd14106	304-506	STKc_DRAK
cd10352	145-238	SH2_a2chimerin_b2chimerin
cd14037	260-451	STKc_NAK_like
cd14169	261-471	STKc_CaMKI_beta
cd14157	272-453	STKc_IRAK2
cd14041	306-466	STKc_TLK2
cd14049	268-510	STKc_EIF2AK1_HRI
cd11848	83-136	SH3_SLAP-like
cd06657	268-459	STKc_PAK4
cd06645	265-451	STKc_MAP4K3
cd05597	269-452	STKc_DMPK_like
cd07862	269-454	STKc_CDK6
cd11768	83-135	SH3_Tec_like
cd14167	269-506	STKc_CaMKI_alpha
cd05607	267-473	STKc_GRK7
cd06639	247-508	STKc_myosinIIIB_N
cd14094	285-506	STKc_CASK
cd05583	269-453	STKc_MSK_N
cd11758	83-133	SH3_CRK_N
cd05610	272-413	STKc_MASTL
cd14211	269-513	STKc_HIPK
cd11769	83-133	SH3_CSK
cd11877	84-133	SH3_PIX
cd14112	281-466	STKc_Unc-89_rpt2
cd09930	144-233	SH2_cSH2_p85_like
cd14229	269-478	STKc_HIPK3
cd11775	83-135	SH3_Sla1p_3
pfam07714	263-512	Pkinase_Tyr
smart00221	263-512	STYKc
smart00219	263-512	TyrKc
smart00220	264-506	S_TKc
pfam00069	263-508	Pkinase
COG0515	264-529	SPS1
PTZ00267	379-529	PTZ00267
PTZ00024	257-463	PTZ00024
PLN00034	267-460	PLN00034
PTZ00426	267-452	PTZ00426
PTZ00263	244-452	PTZ00263
PLN00009	300-461	PLN00009
PTZ00283	365-504	PTZ00283
PHA03209	264-452	PHA03209
PHA02988	280-515	PHA02988
PRK13184	267-525	pknD
TIGR03903	285-470	TOMM_kin_cyc

Ontology Information

HPRD ID	4846
Molecular Class	Tyrosine kinase
Molecular Function	GTPase activity (GO:0003924)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report