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General Information
- Evidence
- Gene
- mRNA
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- Protein
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- Enzyme
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23103611 | 2013 | Cell line : - Source : Chonnam National University Hwasun Hospital National Biobank of Korea. Sample Type : CRC tumor and Normal tissue No. of Sample : 50 Stage : - | Tissue microarray, immunohistochemistry and immunofluoresecence | Up-regulation | - | FOXF1 protein is overexpressed as well as mislocalized in cancerous epithelial cells and underexpressed/lost in tumor-associated stromal fibroblasts of colorectal adenocarcinomas. FOXF1 is a potential prognostic marker due to its association with the malignancy and metastasis of colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Forkhead boxes |
| Description | This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the regulation of pulmonary genes as well as embryonic development. |
| Chromosome | 16 |
| Location | 16q24 |
| Start | 86510527 |
| End | 86514464 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 3938 |
| OMIM ID | 601089 |
| HGNC ID | HGNC:3809 |
| Unigene ID | Hs.155591 |
| Ensembl ID | ENSG00000103241 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_001451.2 |
|---|---|
| Exon | join(1..1022,2399..3938) | mRNA Sequence | Download Select all |
| Length | 2579 |
CDS Information
| Location | join(44..1022,2399..2559) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS10957.2 |
Protein Information
| Protein ID | NP_001442.2 |
|---|---|
| Protein Name | forkhead box F1 |
| Molecular Wt. (Da) | 39991 |
| Protein Sequence | Download Select all |
| Length | 379 |
| Uniprot ID | P25092 |
| Ensembl Protein ID | ENSP00000261170 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00059 | 48-125 | FH |
| cl00061 | 48-125 | FH superfamily |
| smart00339 | 48-136 | FH |
| pfam00250 | 48-136 | Fork_head |
| COG5025 | 45-133 | COG5025 |
| COG5025 | 47-133 | COG5025 |
Ontology Information
| HPRD ID | 3465 |
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | DNA binding (GO:0003677) |
| Biological Process | DNA repair (GO:0006281) |
Drug Information
No matching records could be found.