CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
FOXM1	2305	forkhead box M1	12	HFH-11, trident, HNF-3, INS-1, MPP2, MPHOSPH2, TGT3

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
21281787	2011	Cell line : - Source : Department of Surgery at the King Faisal Specialist Hospital and Research Center Sample Type : CRC tumor and Normal tissue No. of Sample : 448 CRC, 307 normal matched colorectal mucosa, and 24 benign colorectal adenoma Stage : -	Microarray, Immunohistochemistry, ELISA and Immunoblotting	Up-regulation	-	FOXM1 gene may serve as a useful molecular biomarker and potential therapeutic target. Overexpression of FoxM1 potentiated cell proliferation, cell transformation, and migration/invasion of CRC cells via up-regulation of FoxM1 target genes MMP2 and MMP9 and protected these cells from thiostrepton-mediated antiproliferative effects.

Gene Details

Chromosome 12 - NC_000012.12 (2857681..2877155, complement)
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Gene Type	protein coding
Gene Family	Forkhead boxes
Description	The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.
Chromosome	12
Location	12p13
Start	2857681
End	2877155
Strand	-
Gene Sequence	>gi\|568815586:c2877155-2857681 Homo sapiens chromosome 12, GRCh38.p2 Primary Assembly TTTCAAACAGCGGAACAAACTGAAAGCTCCGGTGCCAGACCCCACCCCCGGCCCCGGCCCGGGACCCCCT CCCCTCCCGGGATCCCCCGGGGTTCCCACCCCGCCCGCACCGCCGGGGACCCGGCCGGTCCGGCGCGAGC CCCCGTCCGGGGCCCTGGCTCGGCCCCCAGGTTGGAGGAGCCCGGAGCCCGCCTTCGGAGCTACGGCCTA ACGGCGGCGGCGACTGCAGTCTGGAGGTGAGCGGGATGCAGCAATGGAGTCCCAGGCCTGGCCTGGGCAC AGGCGGGGAGCAAGGCCTCCGGGCGCGGAGGTCAGGGCGTCTAGCAGCAGGGCACGGGCCACGAGTGGAG ATTTGGGTCACACGGGAAGAATCTGAGCCAGGGTGCAAGTTTTTTCTGCGTCCACCTCCTGGCCGTGGCC TTCTCACTGCTTAAAGCGCCCCTTGGCCTTCCCTGGAAGTCTGACCTCCGCACCCTGCCCGCGGCCTCGG GAGGGCTGGGGTGGCCTACCTTCTTAGGCCGACTGTGGCTGAGATGAAGACTGAGATTGTACTACATTGA GTCAAAGACCAACCTGCATACACACTCCCCTGCTCCCAGGCTGTCTCACCACTAGGCAACACCGCCTCCA TCTTACTTACCCTTTTGCAGGGCCCTTTTCCTGGTTCTTGAGAATGTAGCAAGATTTCCCCGCTCAGGAT GGGGATGGGTCGGAGGAGCCACTCTGGAAGTTTCCCGGGCAAGAAAGTGTTGGCAATAATAATAACGGGC TGGTCAGGAAGTAGAAGAGAAAATTAAGACTTAGATATCCTGTGGAAAAAGAGGAATAATATCTACTGAT TGATGCGGGGAGAGAGGGAAGCCTGGAAAGATCGGAGGTGAAAGTAAAACTGAGATTTGAAGGTAGAGGT GTGGAGGGCCTGTGAACTCTATGCAGATGACAAATGTCAAAAAAGTGCAGTTGCTTTTCAGGGAGAGAAT AAGTGTCCTAAAAAAGAGACAGCCAATTCCTCTGTCTTCCAAAGTTCCGTGAAATAGAATTACACAATTT TGCTTAATGGTAGAATATTCCATGTATCTATTAAAATCAACAAAAGGCCGGGCGCAGTGGCTCACGCCTG TAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGAGTTCAAGACCAGCCTGGCAAACAT GGTGAAACCCTGTTTCTACTAAAAAAAAAAAAAAAAAATTAGCTGGGCATGGTGGTGCATGCCTGTAATT GCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCCGAGGTTGCAGTGAGCTGAGA TTGCGCCATTGCACTCCAGCCTGGGTGACAAGAGCGAAGCTCCGTCTCAAAAAAAAAAAAAAAATTAAAA AAAATCAACAAAAGACTTAAAAAAAAAAGACTACACTGTTAGCATTTCAGAACCACCTTAGTGTAATGAT GATAGCTCATTGTGGTACTAAGAAGACAGGGGTTATAGTCTTATTTCTGGAAAAGAAATTAATAAAGTGG CATGCTTAGTTAAAATATATATAACCACATGCAAGTACTAAAATGCCACTGTATAAATACAATACAAATT GTAAAAGAAAACATGCTTTTTAAATTAGAGCAAGTATAATAGCCTGTGAAATAAATGTCACCCTCTAGAG TTGTTCAGTGCACAAGCTGCACAACTTTACATGGGCCTTCAGTAGAGGTTTCCATTTTATGTGAGGTTTT GTAAACTGGGAGATGATTTTTCCAGTAGTGTGGCAATAGTACAATCTGCCTTTCTTCCCTGATTCTGTGT GCACTGGTCCTATTTACAAAGTAATATAAAAATCAAAAGGCTTGGCCAGACGCGGTGGCTCACGCCTGTA ATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATGACCTGAGGTCAGGAGTTTGAGACCAGCCTGAGCAA CATGGTGAAACCCTGTCTCTACTAAAAATACAAAAACTAGCCGGGCGTGGTGGTGGGCACCTGTAATCCC AGCTACTCAGGAGGCTGAGACGTGGGACTCGCTTAAACCCAGGAGGCAGAGGTTGCAGTGAACTGAGATC GTGCCACTGCACTCCAGCCTGGGTGACAAAGTGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAATTA AAATCCTTTGTCTTGAATGGATTATGGGATCAGAGTTTCATCAGGACTCCTAATTACCATATGCTTTCCT ATTCTAGCATCTTCCATTTCTGTCCATACAGTCATTGCAAGTGATCTATTTATATTATAGTAGGCAATTA TAGAGATTTCCACATATTTGTAGCTATCCCATCCATTTCTGTAGCCAAATATTCTGAAGCTTCAAGGAGA TCTTTGTCTTATCTCCAACCCAGTCCCATTTTTGCCCTTTGAATTGCTTCTGTCTGCTGTAATTTTAGCC TTCTTTTGTCAGTAAAGCTTATCTCCTTATTATCTGAGGTCTTTACAAAAGTCCATGGAATGTTTACCTG GGCCTTTAGGCTCATGTTCCTGGTCATATAAAGAGGAGCACCTTTCTCTAAAAGGACCTCTTCTCAGCCT AAACAATCTCTAACATCTTGCCACTATTTGCATTTTCCAGGGTCCACACTTGTGATTCTCAATGGAGAGT GAAAACGCAGATTCATAATGAAAACTAGCCCCCGTCGGCCACTGATTCTCAAAAGACGGAGGCTGCCCCT TCCTGTTCAAAATGCCCCAAGTGAAACATCAGAGGAGGAACCTAAGAGATCCCCTGCCCAACAGGAGTCT AATCAAGCAGAGGCCTCCAAGGAAGTGGCAGAGTCCAACTCTTGCAAGTTTCCAGCTGGGATCAAGATTA TTAACCACCCCACCATGCCCAACACGCAAGTAGTGGCCATCCCCAACAATGCTAATATTCACAGCATCAT CACAGCACTGACTGCCAAGGGAAAAGAGAGTGGCAGTAGTGGGCCCAACAAATTCATCCTCATCAGCTGT GGGGGAGCCCCAACTCAGCCTCCAGGACTCCGGCCTCAAACCCAAACCAGCTATGATGCCAAAAGGACAG AAGTGACCCTGGAGACCTTGGGACCAAAACCTGCAGCTAGGGATGTGAATCTTCCTAGACCACCTGGAGC CCTTTGCGAGCAGAAACGGGAGACCTGTGGTATGTGGTCTTCCAGGGAAAGGGGTGAGGGAGCCCAGCCT TTCCTCTGTAGTGGCAAGGTGTGTAGTCAGTCTTGATGCTTACAACAGTCAGGCTTCTGGCCGAGCACAG TGGCTCATCCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCACTTGAGGTCAGCAGTTTGG ACTAGCCTGGCCAACATGGTGAAACCCGTCTCTACTAAAAATATAAAAAAACTAGCCGAGCGTGGTGGCA CACGTCTGTAGTCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTGAACCTGGGAGGTGGAGGTTGC AGTGAGCTGAGATTATGCCACTGCACTCCAGCCTGGCCACAGAGGGAGACTCTGTCTCAAAAAAAAAAAT AAAAATGAAAAAAGAAGGGGTCTCAAAAATAAATAAATGAAGAAGGGGTCTCACTATGTTGCCCAGGCTG GTCTCGGACTCCTGAGCTCAAGGGATCCAACCATATGGGCCTCCCAAGGTGCTGGGATTATAGGCATGAA CGACAGCGCCTGACTTCATTTTCCTTCTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGC CCAAGCTGTAGTGCAGTGGTGCAATCTCAGCTCACTGCAATCTCCACCTTCTGGGTTCAAGTGATTCTCC TGCCTCAGCCTTCTGAGTAGCTGGGATTACAGGCACCCGCCACCACACCTGGCTAATTTTGGTATTTTTT AGTAGAGACAGGGGTTTGCCATGTTAGCCAGGTTGGTCTTGAACTCCTGACCTCAGGTGATTCGCCCACC TCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCTGGCCTCATTTTCCTTCTTGATAAA GGAGAAAACTGAAGCAAGAGGAGGAAAATGACTTTTTCTTTAGAGATGCGGTCTCGCACTGTCACCCAGG CTAGAGTGCAGTGGCGCAATCACGGCTCACTCTAGCCTCGAATGCCTGGACTCAAGCCATTCTCCCACAT CAGCCTCCCAAGTAGCTGGGACTATAGGCATGCACCATCATTCCCAGTTAATTTTTTTTTTCTTTTTGCA GAGATGGGGTCCCACTATATTGCCCAGGCTGAAAAGTGACTTTTTTGGTGTGCATATCTCAATAATTCTT TTGTAAGCCTGCCTTGATTGATCTCTAAGGCTCAGTGTGGCTCAGCTTGAAATGCAATTTGAACTATGCT CCTAAATTTGTCCTGAAATGCATAATGGGGCAGAGTAACTTAGAGCCACAATAGATTCAGCATGTGTTCT CCGTCCCTAAAGGCAGAGGTCTTGGACAAGTGATCCCTAGCCACCAATTCTTTCTTTTTTATTTTTTATT TTTCTGAGACAGAGTCTCACTCAGGCTGGAGTGTAGTGGCGCAATGTTGGCTCACTGCAGCCTTCGTCTC CCGGGTTCGAGCAATTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGTGTGCCACCACACCC AGCTAATTTTGTATTTTTAGTAGAGACGAGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACC TCAGGAGATCCACCCGCCTCGCCCTCCCAAAGTGCTAGGATTACAGGTGTGAGCCACTGCACCCGGCCTG CTAGCCACCAATTCTGATGGACACACCTGGGCATCTGATGAGGCAGCTAAGTGGGGTGTTGGATTATTTT CCCTCTAGCAGATGGTGAGGCAGCAGGCTGCACTATCAACAATAGCCTATCCAACATCCAGTGGCTTCGA AAGATGAGTTCTGATGGACTGGGCTCCCGCAGCATCAAGCAAGAGATGGAGGAAAAGGAGAATTGTCACC TGGAGCAGCGACAGGTTAAGGTGAATTGTTCCGTCCCTCACTAAAGAAATCAGATCCAGTGTAGGGAATT CCTAGGTAGGGAAATGGATCAAGTGGCCTGATGGACCAGAATTTCCAAGTTCTGGTATTAGCTCTCCACT TCATGCTATTCTGCATAACTTTTGAGCTATTTTTCTGCCTGGGATCTTTTCTCTCCCATCTGTGAAATTT CCTTGAGGGCAGAGTCCCTTGGTCACTCTGTATTCCAGCCAGCACTGGGTTTAGTATTTTGTCCTTAGTA GGTATTCAGGAAATGATTAAGAGGTCTTCATTTTGGGAATCCACCTGAACTTTAAAGATGCTTCCCAACA GTATGAACAGTATGAATTGAATAGAATACAACAAGTTAATTTTATTAGAAGATATAATATTAATAGCAGA TAAAGTCAGTTATATATATACACGTATATATATTTTTTTTTTTTAAGACAGCGTCTTGCTCTGTTGCCCA GGCTGGAGCGCAATGGTGCAGTCATGGCTCTCTGCAGCCTCGACCTCCAGGGCTCAACTGATCCTTCTAC CTCAGTCTTCCAAGTAGCTGGGACTTGCCAGCTTGGTGCATGCCACCATGCCCAGCTAATTTTTGTATTT TTTGTAGAGATGGGGTTTCGCTATGTTGCCCAGGCTGATTTCAACTCCTGGGCTCTAGTGATCCTCCTGC CTCAGCCTCCCAAAGGGCTGGGATTACAGGCGTGAACCACCAGCCTGGCCTAGATACGAATTTTAAATAC TTCTCTAGCAATCAAAATTGATCTAACCCAATTGTGTAGTCTGGGTTTTTTTCCCACAGTTACCAATATA ACACATCTAGATTCTATTGTATATATGTGTAAATCACTCATTCAACCTTTATTTTCTTTTTTTTCTCAAC TTTTATTTTAGGTTCAGGGGGTACATGTGCAGGTGTGTTACATGGGTATATTGTGTGTCGCTGGGGTTTA GTGTACAAATGATTTTGTCACCCAGGTAGTGAGTATAGTACCTGCTAGGTAGTTTTTCTGTCTCCCCCTC CTCCCACTCTCCACCCTCAAGAAGGCCCTGGTGTCTAGTGTTCCCTTCTTCATATCCATGTGTGCTCAAT GTTTAGCTCCTGCTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGTAGTCTTTCTCTGTCTCCTAGGCTGG AGTGCAGTGCTGCGATTTCAGCTCACTGCTACCTCCACCTCCCAGGTCAAGTGATTCTCCTGCCTCAGAC TTCTGAGTAGCTGGGATTACAGGTGCCCGCTGCCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGG GGTTTCACTATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCGTGATCCACCTGCCTTGGCCTTCCAAA GTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCTCTTTTTTTTTCTTTTTGAGACGGATTCTCTCT TTGTTGCCAGGCTGGAGTGCAGTGGCACAATCTCTGCTCACTGAAACCTCTGCATCCCAGGTTCAAGTGA TTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTATAGGCGCCCGCCACCACGCCCGGCTAATTTTTTTA TTTTTAGTAGAGATGGGGTTTCACCATGGTGGCCAGGATGGTCTCAATCTCTTGACCTCGTCATCCACCC GCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCGTACCCAGCCTAGTTCCTACTTATAAG TGAGAACATGCAATATTTGGTTTTCTGTTCCTGCATTAAATCGCTTAGGATCATAGCCTCCAGCTCAACA ATCTTTAAAAGTGAAAATTTGGCCAGGCGCGATAACTCATGCTTGTAATCACAGCACTTTGGGAGGCCAA GGTGAGTGGATCACCTGACGTCGGGAGTTCCAGACCAGCCTGACCCCGCCTCTACTAGCAATACAAAATT AGCTGGGTGCAGTAGTACATGCCTATAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAAC CCAGGAGGCAGAGCTTGCGGTGAGCCAAGATCGTGCCATTACACTCCAACCTGGGCAACAAAAGTGAAAC TCTGTCTCAAAAAAAAAAAAAAAGTGAAAATTTACATGCGTGTATATGTAAGTAAATATTAATTGTGCTA TATACATAAAATTTGTGTACTTTAGAAAGTAATATCTCCAATTTTAAAAATGTGAATGAGACCGGGCATA GCGGCTGACAATTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATTGCTTGAGCCCGTAAGTTCT AGGCCAGCCTGGGCAACATAGCAAAATCCTGGTCTCTACTACTAAAAATACGAAAAAAAAAAAAAAAATC GCCAGGCGCAATGGCTCATGCCTGTAATCCCATCACTCTGGGAGGCCAAGGTGGGTGGATCACCTGAGGT CAGGAGTTCGAGACTAGCCTGGCCAATATGGTAAACCCCATCTCTACTAAAAATACAAAAAAAGTAGCTG GGCGTGGTGGCAGGCACCTGTAATCTCAGCTACTTGGGAGGCTGCAGCAGGAGAATCGCTTGAACCCAGG AGGCAGAGGTTGCAGTGAGCCGAGATCGTACCATTGTACTCCAGCCTGGGCAACAAGAGTGAAACTCCAT CTCAAAAAAAAAAAAAAAATTAGCTGGGCGTGGTGGTGTATGCCTGTAGTCCCAGCTACTTGGAGGCTGA GACAGGAGGATCACCTGAGCCTGGGAAGGTCAAGGCTGCAGTGAGCTGTGATCCAGCCACTGCACGCTAT CCTGGGTGACACAGTGAGACCCTGTCTCAAAAAAAGAAAAAGAAATGTGATTGATCAGCTCTTTGCCTAA AACTTAGCTAACTGTGTGCTTTGCAGACATTGTCTGACTCATAGTCTTGAGAATGTTTCTCTCATACAAA CATTGAAATGAGATGCGTTTATTCACAGCACATCAGGAACAGAAATGGGACTAAGACCTAGGTTTCTAGA CCCAAAAGTCTGAAAAACGGGCGTGGTTTTAGTGTAACATCAATGCTTTGAGAATCAAAGTACATACTCA AACTTTCCTAAGAAATTTCAACTGGAAGGGACTGGATTTTCTCCAAATTCAACAAAATGATGGATGACAA AACCAGTTTCTTATTGGCTAGGGTCTAGGCTAGATCATCTCCAAGATTCTTCCCAACTCTAAAATTTTAT TCTATGAGATAGTGGTCTCAGATGAGTTTGTTTCTAGACCGTCCTATGGGATAAAGGTTTCTCTAGATGT TCTTCAAGGGCTTGGGTTGGGGGTGCTTCTCATGAACTCTTTCATGTCATTCCCTGTGTCATAACCCTCA GGTTGAGGAGCCTTCGAGACCATCAGCGTCCTGGCAGAACTCTGTGTCTGAGCGGCCACCCTACTCTTAC ATGGCCATGATACAATTCGCCATCAACAGCACTGAGAGGAAGCGCATGACTTTGAAAGACATCTATACGT GGATTGAGGACCACTTTCCCTACTTTAAGCACATTGCCAAGCCAGGCTGGAAGGTAATGTGTCCCACAGC AACCAAAATCAAGGTCAGCCCAGCCTGACAGTCTCTCCAGTGCTGTACTGCAACTTGTATCTGGGACAGC AGTTAAGTGCAAAGGACACTAGAATGATAAACAAATGTATCTTTTAGATTGTGACTCAATCTTATTGAAT CCAGGCAAAATCATTAAGAAGAGCTCCTTAACTACTTCATGTGTTACTACCTAAAGTCCATGGAGGGTCT TCAATGTAGCACTCAAGCCCACTTTTCTGCTACACTCAACAGCCGTCCTAGATGCCAGCAGCTAGAGTGG CTAAGTAGTTTTATGAAAATGTCTTGATTAAAAAAAAAAATGCTGTCTGTGAGCCTCATGACCCAAGATG TCATCTCCTGTAGCGTCACATAGCATTTCTAGTGGGCAGGGGTTTTCCTTTCACTTCATTCATGGAAAGA CCGAGATGCCTGTGAGTCAACATAGCTCACGCAGTTGGTCGGTGTCAGAGCCACAAATGAGGTCTTCTGA CGGGTGCTCAATTCCAAGTCAAGTGTGCTTTGTTTTCCTCATGGTAGAACTCTTTCTTTTTTTTTTTTTT TTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAATGGCAGATCTCAGGTCACTGCAACC TCCTCCGCCTCCAAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCATGCG CCACCACGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGACAGTGTTTCACCATGTTGGTCAGGCTGGTC TCGAACTCCTAACCTCAAATGATCCACCCGTCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCA CCACACCTGGCCCCTCATGGTAGAACTATGTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCA GGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCTGGGTTCACGCCATTCTCCTGC CTCAGCTTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCTGGCTAATTCATGGTAGAACTTTT AATTTTACTCCCTTCCATCAGCTTACTTTCCTAGTTTTTTGTTTGTTTGTTTTTTGAGACAGGGTCTCAC CCTGTTGCCTGGGCTGGAGTGCAGCCTCAGCCCCCTGGGCTCAAGCTCTTCCCTCCTCAACATCCCAAGT AGCTGGGATAACAGGTGCACCACCACAGTCCGCTAATTTTTTTTTTGTAGAGACAGTTGCCCAGGCTGGT TACTATGTTGCCCAGGCTGGTCTGAACTCCTAGTCTCAAGCACTCCTCCTGCCTTAGCCTCTCAGTGCAC TGTGATTACAGGCGTGAGCCACCACACCCAGCCTTAATTTCCTAGTTTCTTGTTTGTTTGTTTGAGACGG GGCCTCACTCTGTCACCCAGGCTGGAGTGCAGTGACATGATCTTGGCTAACTTCAACCTCTGCCTCCCAG GTTCAAGTGATTCCCCTGCCTCAGCCTCCCGAGTAGCTGGGACTAAAGGCATGCGCCACCATGCCTGGCT AATTTTTATATTTTTGATAGAGACAGGGTTTCACCATGTTTGCTAGGCTGGTCTCAAACTCCTGGCCTCA AGTGATCCACTCACCTTGGCCTCCCACAGTGCTGGGATTATAGGCGTGAGCCACCACGCCGGGCCTAATT CCCTAGTTTCTTAATTTCTCTGAGCCACCTTTCTTGCTATTGATCACTACCTCACAGCCTTACTCTGCTT TTCTAGCCCCTGACAGCTATCTAGGTCTTTTCTTTATCACAATCTAAGGTTGGCATCAGTCTTTATTCCC GTAGAATAGATGGGTTTATGGCTGAAGGTGACGGCTCTGCGGTGTGGAGTGTCAGGAGAGTTGCCAAGAG GGCTGCAAAGACACCAGACGAAGCCTGTGCTGAGCACAGTGGGAGGGGCCTGAGGCTGGTTTCCCCATGT GTTTGAAGGGTGATGTTTCTGAATCTAAAGTAGCTGATAACCAGTTGTCTTGCTCTTCTTCCAGAACTCC ATCCGCCACAACCTTTCCCTGCACGACATGTTTGTCCGGGAGACGTCTGCCAATGGCAAGGTCTCCTTCT GGACCATTCACCCCAGTGCCAACCGCTACTTGACATTGGACCAGGTGTTTAAGGTGAATGCCCTGCTTTC CTCTAAATAGGGCCTAAGTTGGAGGTTGTCATAGCCATCTCAAAAGGAAACAAGTTCTGCTAGTGATGCT TTCATTTGATCAGGGGAGAGTTAGAAGCCAGCCACCCAATTAGTGACTTGCACAAAACCCAGTGAATTAA GTACACTTGACAAATACCAAATGACACATTTTTGTGCCAGACCAGAGCAAGGAGAAGGCTGTTCTGACCC AACAGAAAGGGCTCCCCAGGGCAGTGTTTTCCTAACTTCCCTGTGAATGGGAATTGCCTGGGACATTGTT AAAACACAGCTTCCCAGACCCCTCTCTTGGGGCTCTTGATTTAGTGCTTCTGGGATGGGCCCAGGAATTT GTATTTTTAGCAAGCATCTCAGGTGATTCTTACAAGAAATTCTGGGAATGCTTGCTCTAAAAAAAGCCCT TCCTGCTGGGTGTGGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTA AGGTCGGGAGTTGGAGACCAGCCTGACCAACATGGAGAAACTCCGTCTCTACTAAAAATACAAAAATTAG CTGGGTGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCCCTTGAACCC AGGAGGCGGTGGTTGTGGAGAGCTGAAATCGCACCATTGCACTCCAGCCTGGGCAATAAGAGTGAAAGTC TGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAGCCTGCCTTAGGCTGGAGACCAGAAGCTGAGCTACCAG AACGTCTTTTCAGAAAGAAGTTATTTTGGTTTTTCAGAGTGCCCATAAGGCTGCTGGTAGCTGTAACCAT TCTCCTGGGAGGGGCAGTTGTCTGGGGTGTCTTTTGTCATCAGTCAGGAATAAGTGTTTTTCCCAATCCG GTCAAATTGACCACGTTGGTGGTAACTTCATCTCATTTCTCTCCCACAATGCCTGGCCGCCACCAGCCAC TGGACCCAGGGTCTCCACAATTGCCCGAGCACTTGGAATCAGTAAGGTTCTTTCCCTCTGGCTCGGGGCT TGGCCTTGTTTTCCTTTCACTGCTCAGCATGGCTTTAGTGGACAGAGACAAGATGTGATGTGGGGAAGGG TCCCTATGGCCATGTTTTGTCTAGGTGCCAGCCCTAGACACAGAACACCCTGAGGGTCAGGCACACACCC ACTTCCCTCCCCTTCCATGGGCATCACAAGGGCACACTGAGCAGAGCAGGGCACAGCAGGGGAGCATGCT GCAGCAGCCACAAGCGCATGGCACCAGCCTCAGGGGCGGCAGTTCGTTCGCTCACTTTTGTGCCTAGCTT TTCTTTGCCACGCATATAGCTACCTGCTCTGGCATCCCCCAGGGGTGTTGAGGACACGTGGGTGAAGCGG TAGTGCCACTCTGCCATCATGTGTCTGTAGGCCACCCACCTGCCCACTCATCACAGTTTTGGAGACTGCT CGCCTACGTCCATCCCCTCAGGTTGGCCTCCTCTCTCTGGGCTGTCATTAACTCAAGCACACACCACCAG AGCAGCTGGTGGGGTTTTGCCATCCCCTCTTTACCTTATTGTGTTAACATAGGTTTCTTTCTCTCCCCAT CTGCCACAAGCAGCAGCAGAAACGACCGAATCCAGAGCTCCGCCGGAACATGACCATCAAAACCGAACTC CCCCTGGGCGCACGTTAGTATGGGAGAGTGGGCCTTGGGCCTGGTCCTTGTTCTGGGGCCATATCTTTAG GGAACCAGACTCTGGGATTCTGTTCCCACCTCAAAGGGATCTGAGCCCAGAGAAGGAGAGCAAAGCTCCT GGGGCTGAGAAGGGGTGTACTCCAGTCCCCCTGCTCCTGATCTCTCGTGTTTCCTCCTAGGGCGGAAGAT GAAGCCACTGCTACCACGGGTCAGCTCATACCTGGTACCTATCCAGTTCCCGGTGAACCAGTCACTGGTG TTGCAGCCCTCGGTGAAGGTGCCATTGCCCCTGGCGGCTTCCCTCATGAGCTCAGAGCTTGCCCGCCATA GCAAGCGAGTCCGCATTGCCCCCAAGGTGGGTGTCCTATTTTCCTCTGAAGAGAGATTCTGGCCAATTAA GAATGTTGGACCTTCAGCTTGCAAAGCACTCTGATAAGTGTTCCTTGAGAGCTTATAAATCTAGTTGGGT AGAAAAGGCATAAAAACATAGGGAAGTGTAATAGCATTAGAAGAGCTAAAAAGGTATTTGGATTACAATG TAAGTGGTGTCAGAAGGCCCATAAATACCTGATGAGCTTGTAAGAATTCAGACAAAAGTGATTGTGATAG ATGGGCTAGGATTATTAAGGAAGATACACAAGGGAGGCAGGCCTTAGAAAGAGATGGATTTGGCCGGGCG CTGTGGCTTACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCATGAGGTCAGGAGTTTG AGACCAGCCTGGCCAACGTGGCGAAACCCCGTCTCTACTAAAAAATACAAAAATTAGCTGGGCTTGGTGG CACATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCTGGAGAATCACATGAGCCCAGGAAGGGAAGTT GCAGTGAGCCGAGATCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCAAAAAAAAAAAAAG AAAAGAAAGAAGTGGATTTGAGGCTAGACGCTGTGGGTCTCACTTGTAATCCCGACACTTTGGGAGGCCG AGGCAGGGGTATTGCTTACAGCCAAGAGTTCGAGACCAGCCTGGGCAACATAGCAAGACCCCAGTCTCTG CTAAAAATGCAAAAAAAAAAATTAGCCACGGTGGTAGTACATGCCTGTGGTACCAGCTACTCAGGAGGCT GAGGCAGAAGGATCACTTGAGTCCAGGAGGTTGAGGCTGCAGTGAGCCCTGTTTGCACCACTGCACTCCA GCCTGGGCAACAGTGAGGCCCTGTCTCAAAAAAGAAAAGAAAAAAAGTAGATTTGGGTAAGCAAACAGGT GTAGAGAGAGCATGCTAATGGGCAGTGCCATGGAGGCGGGAAATGCAGTTCGTACCTGGCAGTAGTAAAG TGACTGGGTCAGACTAACTCAGGGTTTCTCAAGTACTATTCACGTTGACAGCTGGAGAATTCTTTGTTGG GCGTGGGAGGGACTGTCCTGTGCACTGAAGGGTGTTTAGCAGTATCCCTTGTTTTCCCCACTAGACGCCA GTAGCACCCACCACAGGCGCGGCAATCCAAATGCCTCCAGACATTGCCAAATGTCCCCTGGCAGGGAGGG AATCACCCCTGCTTGAGTATCACTGGTCTAGCTTGAGGGGAAGGTGAGAAGGGTAAATTCAGAGCCAACT TGGATCAGCCATCAGATCTGCACTTAACACTGTTAAAGGGTTCTGTGAGTACGGGCTGACATGTAACCAA AGTGAAAAGCTTCCCCCATCCCCTTCAGAGAGATGAAAATAGCATAGAGTCTGGAGTTTAGAGCGACTTG GGTTTGCTTTTTTTTTAATATATAAAATCTTTTAGGCCATGCACAGTGGCTCACACCTATAATCCTAGTA TTTTGGGAGGCCAAGGCAGGAGGATCACTTGAGGCCAGGAGTTCAAGACCAGCCTGGGCAGCAAAGTAAG ACCCTGTCTGTAACAAAAAAAAAAAAATTTTTTTTTAATTAGCCAGGCATTTTCATGTATACCTGTTGTC CCAGCCACTTGGGAGGCTGAGGCAGAAGGATTACTTGAGCTCCAGAGCTGGAGGCTGCAATGAGCTATAA TCGTGCCACTGCATTCTAGCTTAGGCAACAAAATGAGACCCTGTCTCTAAAAAACATTTTCTTTAATTAT AAATAAAACATATTACACACAAAATTATACCACACATACATAATTTAGCGTAAATTCATTCATGTGGCCG TAGCATGTGCCCTGTTTGGGTTTTCATGCAGTGGGTTTTCTCCCCTTTCCTTTTTGGCTCCCTCTCCACC CTACCATCACCCACATCACCCCTACTCCCAAGATAACTGGTTGATAATTTATGATGCTTTCTTGCATATT TTATCAATGCTCTTAGTTATACTATACATGTATAGCGATAGCCATTTTATATGTACACATACAACACACA GAACATTGATAATGTAATCATGTTGTGCATACTTCTCTACATGTCTCTTTTTTTTTTTTTTTTTCCTGAG ACGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAATGGCATGATCTTGGCTCACTGCAACCTCCGCCTC CTGGGTTCAAGCGATTCTCCTGCCTCGGCCTCCTGAGTAGCTGCGATCACAGGCGCACGTCACCACGCCC AGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAGCTCCTGAC CTCATGATCCGCCTGCCTTGGCCTCCCAAAGTGTTGAGATTACAGGAATGACCCACCACGCCCAGCCTCT ACATGTCTCTAACTCAACAATGCCTCATGGAATTTCTTCCAAGTCACTTGGCATAGTCCTAATTCATTAT TTTTTAGTGTCCATGTAATATTCCATGATGTGGCTACACCACAGATTTTTCAGCCATTCCACTTTTATGG ACAGATTCTGTTTCTCAAATTTTGCCCAATGAACGACACTGCAATAAATATGTTTGCAAGGATCTCTCTT ACTAGTGCTTTCATTTCTCTAGGATAGAGTCCCAGATGTGAGATTGTTGGGTGAGAAGGTATTTTAAATT CTACTAAATATTGCTAGATTGCTTTCCAAAAAAGCTATGATAAGTCATGTTTAAACCAGCAATATATGAT AAGATCTATATCTTTGCCAGCAATTGGTATTATTAGTCTGTTTAATATCTGCCAATCTAATATGTATAGG TTATATCTTCTTAATTTTTTAAAATGTTTTATTTATTTATTTTTAAATTTTTTATTTCCATAGGTTTTTG GGGAACAGGTGGTGTTTGGTTACATGAGTAAGTTCTTTAGTGGCGATCTGCGAGATTTTGGTACACCCAT CACCAGCTTGTTTAATTTTATCTTTCTTTGTTTATCAGTAAGTCTGAGCACCTTGTCATTATGTTTGGTG ACTTGGAATTGTCCTCTATGAATTGGTTATTTATGAACATTGCCCATTTTTATATAGGTTTTGTTATCAA TTTGTGAGAGCTCTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGG CGTGATCTCAGCTCACTGCAGACTCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTA GCTGGGATTACAGGCGCCCACCACTGCGCCCAGCTAATTTTTGTATTTTTTAGTAGAGACAGGGTTTCAC CATCTTGGCCAGGCTGGTCACGAACTCCTGACCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGGG ATTACAGGCATAAGCCACCACGCCCAGCCTGTGAGAGTTTTTTTTTTTTTTGAGATGGAGTCTTGCTATG TCACCCAGGCTGAAGTACAGTGGTGTGATCTTGGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCGTGC CTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCATGCCACCACGCCCGGCTAATTTTGTATTTTTAGTAG AGACAAGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTTCTGACCTCAGGTGATCTGCCTGCCTTGGC CTCCCAAAGTGCTGGATTACAGGCGTGAGCCACCGCACCCAGCCCCCTGTGAGAGCTCTTTGTTGTTAAA ATAATCTTCTTTCTTTTATGCTGAAGATATTTTTCTACTTCTATTGTTTATCTCTTTACTTTCCTTTCTT TTCTTTTCTGAGACAGGATCTTGCTATGTTGCCTAGTCTGGAGTGCAGTGGTGTAATGAAGGCTCACTAC ATCCTTGACCTCCCAGGCTCAAGTGATCTTCCCACCTCAGCCTCCCACCTGTAGCTGGAACTACAGGTGC ATGCCACCACATCCAGCTAATTAAAAAAAATTTTTTTGTAGAGATGGGATCTCACTATGTTGCTCAGGCT GGTCTCAAACTGGCCTCAGTGTCTTGCAGTGCTGGGATTACAGGCATTGTTTGTTGTTTCTTAACTTTGT TTATGGTATCTCTTGCCACAGTAAAATTTTAAAGTTTTATGTAGTCAAATGTCTCTCTTCTCTTTTACAG TTTCTGGGTTTCCAGTCTTGGTTAAGAAGGTCACCCGCACCCTCAGATTGTATATGTAGTCTCCTAGATT CTCTTTCAGGATTTGTATGATTTTAAGGTTTTCATTTTTTTTTTAAAGCCAGTCAAATTTAGCAGTTGGG GGTTGTGTACCAACTTTAGTGACAATAATGTCACTACCCGCTACCATCAGAGCAGCCTAAGGTTCTTATT TTCATGCATTAAATCTTTGTATACAGTGTAAGACAAGCATGCAATTTTATTTCCTCTCGGATGAATGCTA TTATAATTATGCCACTACATACTACATACCCGCATCTTTTACCCCCAGAATTGAACTACCAACTTCAACA TACATCGTATTCTCATATTTAATAGATTTTAAGACTTCAAAACGACACAAAGAGGATCAGAACCCGTATG TGATATTTTTGTGCGTCCTGTCTGGTGACCGTTGGTTCACCTTATCTCTGTTTCCCTTTCAGGTGCTGCT AGCTGAGGAGGGGATAGCTCCTCTTTCTTCTGCAGGACCAGGGAAAGAGGAGAAACTCCTGTTTGGAGAA GGGTTTTCTCCTTTGCTTCCAGTTCAGACTATCAAGGAGGAAGAAATCCAGCCTGGGGAGGAAATGCCAC ACTTAGCGAGACCCATCAAAGTGGAGAGCCCTCCCTTGGAAGAGTGGCCCTCCCCGGCCCCATCTTTCAA AGAGGAATCATCTCACTCCTGGGAGGATTCGTCCCAATCTCCCACCCCAAGACCCAAGAAGTCCTACAGT GGGCTTAGGTCCCCAACCCGGTGTGTCTCGGAAATGCTTGTGATTCAACACAGGGAGAGGAGGGAGAGGA GCCGGTCTCGGAGAAAACAGCATCTACTGCCTCCCTGTGTGGATGAGCCGGAGCTGCTCTTCTCAGAGGG GCCCAGTACTTCCCGCTGGGCCGCAGAGCTCCCGTTCCCAGCAGACTCCTCTGACCCTGCCTCCCAGCTC AGCTACTCCCAGGAAGTGGGAGGACCTTTTAAGACACCCATTAAGGAAACGCTGCCCATCTCCTCCACCC CGAGCAAATCTGTCCTCCCCAGAACCCCTGAATCCTGGAGGCTCACGCCCCCAGCCAAAGTAGGGGGACT GGATTTCAGCCCAGTACAAACCTCCCAGGGTGCCTCTGACCCCTTGCCTGACCCCCTGGGGCTGATGGAT CTCAGCACCACTCCCTTGCAAAGTGCTCCCCCCCTTGAATCACCGCAAAGGCTCCTCAGTTCAGAACCCT TAGACCTCATCTCCGTCCCCTTTGGCAACTCTTCTCCCTCAGATATAGACGTCCCCAAGCCAGGCTCCCC GGAGCCACAGGTTTCTGGCCTTGCAGCCAATCGTTCTCTGACAGAAGGCCTGGTCCTGGACACAATGAAT GACAGCCTCAGCAAGATCCTGCTGGACATCAGCTTTCCTGGCCTGGACGAGGACCCACTGGGCCCTGACA ACATCAACTGGTCCCAGTTTATTCCTGAGCTACAGTAGAGCCCTGCCCTTGCCCCTGTGCTCAAGCTGTC CACCATCCCGGGCACTCCAAGGCTCAGTGCACCCCAAGCCTCTGAGTGAGGACAGCAGGCAGGGACTGTT CTGCTCCTCATAGCTCCCTGCTGCCTGATTATGCAAAAGTAGCAGTCACACCCTAGCCACTGCTGGGACC TTGTGTTCCCCAAGAGTATCTGATTCCTCTGCTGTCCCTGCCAGGAGCTGAAGGGTGGGAACAACAAAGG CAATGGTGAAAAGAGATTAGGAACCCCCCAGCCTGTTTCCATTCTCTGCCCAGCAGTCTCTTACCTTCCC TGATCTTTGCAGGGTGGTCCGTGTAAATAGTATAAATTCTCCAAATTATCCTCTAATTATAAATGTAAGC TTATTTCCTTAGATCATTATCCAGAGACTGCCAGAAGGTGGGTAGGATGACCTGGGGTTTCAATTGACTT CTGTTCCTTGCTTTTAGTTTTGATAGAAGGGAAGACCTGCAGTGCACGGTTTCTTCCAGGCTGAGGTACC TGGATCTTGGGTTCTTCACTGCAGGGACCCAGACAAGTGGATCTGCTTGCCAGAGTCCTTTTTGCCCCTC CCTGCCACCTCCCCGTGTTTCCAAGTCAGCTTTCCTGCAAGAAGAAATCCTGGTTAAAAAAGTCTTTTGT ATTGGGTCAGGAGTTGAATTTGGGGTGGGAGGATGGATGCAACTGAAGCAGAGTGTGGGTGCCCAGATGT GCGCTATTAGATGTTTCTCTGATAATGTCCCCAATCATACCAGGGAGACTGGCATTGACGAGAACTCAGG TGGAGGCTTGAGAAGGCCGAAAGGGCCCCTGACCTGCCTGGCTTCCTTAGCTTGCCCCTCAGCTTTGCAA AGAGCCACCCTAGGCCCCAGCTGACCGCATGGGTGTGAGCCAGCTTGAGAACACTAACTACTCAATAAAA GCGAAGGTGGACATG Download Select all
Length	19475
OMIM ID	602341
HGNC ID	HGNC:3818
Unigene ID	Hs.735243
Ensembl ID	ENSG00000111206
PharmGKB ID	-

mRNA Information

mRNA ID	NM_001243089.1
Exon	join(1..236,2631..3179,4912..5060,8402..8593,10635..10763, 12404..12473,12661..12836,17493..19475)
mRNA Sequence	>2305 TTTCAAACAGCGGAACAAACTGAAAGCTCCGGTGCCAGACCCCACCCCCGGCCCCGGCCCGGGA CCCCCTCCCCTCCCGGGATCCCCCGGGGTTCCCACCCCGCCCGCACCGCCGGGGACCCGGCCGG TCCGGCGCGAGCCCCCGTCCGGGGCCCTGGCTCGGCCCCCAGGTTGGAGGAGCCCGGAGCCCGC CTTCGGAGCTACGGCCTAACGGCGGCGGCGACTGCAGTCTGGAGGGTCCACACTTGTGATTCTC AATGGAGAGTGAAAACGCAGATTCATAATGAAAACTAGCCCCCGTCGGCCACTGATTCTCAAAA GACGGAGGCTGCCCCTTCCTGTTCAAAATGCCCCAAGTGAAACATCAGAGGAGGAACCTAAGAG ATCCCCTGCCCAACAGGAGTCTAATCAAGCAGAGGCCTCCAAGGAAGTGGCAGAGTCCAACTCT TGCAAGTTTCCAGCTGGGATCAAGATTATTAACCACCCCACCATGCCCAACACGCAAGTAGTGG CCATCCCCAACAATGCTAATATTCACAGCATCATCACAGCACTGACTGCCAAGGGAAAAGAGAG TGGCAGTAGTGGGCCCAACAAATTCATCCTCATCAGCTGTGGGGGAGCCCCAACTCAGCCTCCA GGACTCCGGCCTCAAACCCAAACCAGCTATGATGCCAAAAGGACAGAAGTGACCCTGGAGACCT TGGGACCAAAACCTGCAGCTAGGGATGTGAATCTTCCTAGACCACCTGGAGCCCTTTGCGAGCA GAAACGGGAGACCTGTGATGGTGAGGCAGCAGGCTGCACTATCAACAATAGCCTATCCAACATC CAGTGGCTTCGAAAGATGAGTTCTGATGGACTGGGCTCCCGCAGCATCAAGCAAGAGATGGAGG AAAAGGAGAATTGTCACCTGGAGCAGCGACAGGTTAAGGTTGAGGAGCCTTCGAGACCATCAGC GTCCTGGCAGAACTCTGTGTCTGAGCGGCCACCCTACTCTTACATGGCCATGATACAATTCGCC ATCAACAGCACTGAGAGGAAGCGCATGACTTTGAAAGACATCTATACGTGGATTGAGGACCACT TTCCCTACTTTAAGCACATTGCCAAGCCAGGCTGGAAGAACTCCATCCGCCACAACCTTTCCCT GCACGACATGTTTGTCCGGGAGACGTCTGCCAATGGCAAGGTCTCCTTCTGGACCATTCACCCC AGTGCCAACCGCTACTTGACATTGGACCAGGTGTTTAAGCAGCAGCAGAAACGACCGAATCCAG AGCTCCGCCGGAACATGACCATCAAAACCGAACTCCCCCTGGGCGCACGGCGGAAGATGAAGCC ACTGCTACCACGGGTCAGCTCATACCTGGTACCTATCCAGTTCCCGGTGAACCAGTCACTGGTG TTGCAGCCCTCGGTGAAGGTGCCATTGCCCCTGGCGGCTTCCCTCATGAGCTCAGAGCTTGCCC GCCATAGCAAGCGAGTCCGCATTGCCCCCAAGGTGCTGCTAGCTGAGGAGGGGATAGCTCCTCT TTCTTCTGCAGGACCAGGGAAAGAGGAGAAACTCCTGTTTGGAGAAGGGTTTTCTCCTTTGCTT CCAGTTCAGACTATCAAGGAGGAAGAAATCCAGCCTGGGGAGGAAATGCCACACTTAGCGAGAC CCATCAAAGTGGAGAGCCCTCCCTTGGAAGAGTGGCCCTCCCCGGCCCCATCTTTCAAAGAGGA ATCATCTCACTCCTGGGAGGATTCGTCCCAATCTCCCACCCCAAGACCCAAGAAGTCCTACAGT GGGCTTAGGTCCCCAACCCGGTGTGTCTCGGAAATGCTTGTGATTCAACACAGGGAGAGGAGGG AGAGGAGCCGGTCTCGGAGGAAACAGCATCTACTGCCTCCCTGTGTGGATGAGCCGGAGCTGCT CTTCTCAGAGGGGCCCAGTACTTCCCGCTGGGCCGCAGAGCTCCCGTTCCCAGCAGACTCCTCT GACCCTGCCTCCCAGCTCAGCTACTCCCAGGAAGTGGGAGGACCTTTTAAGACACCCATTAAGG AAACGCTGCCCATCTCCTCCACCCCGAGCAAATCTGTCCTCCCCAGAACCCCTGAATCCTGGAG GCTCACGCCCCCAGCCAAAGTAGGGGGACTGGATTTCAGCCCAGTACAAACCTCCCAGGGTGCC TCTGACCCCTTGCCTGACCCCCTGGGGCTGATGGATCTCAGCACCACTCCCTTGCAAAGTGCTC CCCCCCTTGAATCACCGCAAAGGCTCCTCAGTTCAGAACCCTTAGACCTCATCTCCGTCCCCTT TGGCAACTCTTCTCCCTCAGATATAGACGTCCCCAAGCCAGGCTCCCCGGAGCCACAGGTTTCT GGCCTTGCAGCCAATCGTTCTCTGACAGAAGGCCTGGTCCTGGACACAATGAATGACAGCCTCA GCAAGATCCTGCTGGACATCAGCTTTCCTGGCCTGGACGAGGACCCACTGGGCCCTGACAACAT CAACTGGTCCCAGTTTATTCCTGAGCTACAGTAGAGCCCTGCCCTTGCCCCTGTGCTCAAGCTG TCCACCATCCCGGGCACTCCAAGGCTCAGTGCACCCCAAGCCTCTGAGTGAGGACAGCAGGCAG GGACTGTTCTGCTCCTCATAGCTCCCTGCTGCCTGATTATGCAAAAGTAGCAGTCACACCCTAG CCACTGCTGGGACCTTGTGTTCCCCAAGAGTATCTGATTCCTCTGCTGTCCCTGCCAGGAGCTG AAGGGTGGGAACAACAAAGGCAATGGTGAAAAGAGATTAGGAACCCCCCAGCCTGTTTCCATTC TCTGCCCAGCAGTCTCTTACCTTCCCTGATCTTTGCAGGGTGGTCCGTGTAAATAGTATAAATT CTCCAAATTATCCTCTAATTATAAATGTAAGCTTATTTCCTTAGATCATTATCCAGAGACTGCC AGAAGGTGGGTAGGATGACCTGGGGTTTCAATTGACTTCTGTTCCTTGCTTTTAGTTTTGATAG AAGGGAAGACCTGCAGTGCACGGTTTCTTCCAGGCTGAGGTACCTGGATCTTGGGTTCTTCACT GCAGGGACCCAGACAAGTGGATCTGCTTGCCAGAGTCCTTTTTGCCCCTCCCTGCCACCTCCCC GTGTTTCCAAGTCAGCTTTCCTGCAAGAAGAAATCCTGGTTAAAAAAGTCTTTTGTATTGGGTC AGGAGTTGAATTTGGGGTGGGAGGATGGATGCAACTGAAGCAGAGTGTGGGTGCCCAGATGTGC GCTATTAGATGTTTCTCTGATAATGTCCCCAATCATACCAGGGAGACTGGCATTGACGAGAACT CAGGTGGAGGCTTGAGAAGGCCGAAAGGGCCCCTGACCTGCCTGGCTTCCTTAGCTTGCCCCTC AGCTTTGCAAAGAGCCACCCTAGGCCCCAGCTGACCGCATGGGTGTGAGCCAGCTTGAGAACAC TAACTACTCAATAAAAGCGAAGGTGGACATGAAAAAAAAAAAAAAAAAAA Download Select all
Length	3506

CDS Information

Location	join(2678..3179,4912..5060,8402..8593,10635..10763, 12404..12473,12661..12836,17493..18518)
CDS Sequence	>lcl\|NM_001243088.1_cds_NP_001230017.1_1 [gene=FOXM1] [protein=forkhead box protein M1 isoform 4] [protein_id=NP_001230017.1] [location=284..2530] ATGAAAACTAGCCCCCGTCGGCCACTGATTCTCAAAAGACGGAGGCTGCCCCTTCCTGTTCAAAATGCCC CAAGTGAAACATCAGAGGAGGAACCTAAGAGATCCCCTGCCCAACAGGAGTCTAATCAAGCAGAGGCCTC CAAGGAAGTGGCAGAGTCCAACTCTTGCAAGTTTCCAGCTGGGATCAAGATTATTAACCACCCCACCATG CCCAACACGCAAGTAGTGGCCATCCCCAACAATGCTAATATTCACAGCATCATCACAGCACTGACTGCCA AGGGAAAAGAGAGTGGCAGTAGTGGGCCCAACAAATTCATCCTCATCAGCTGTGGGGGAGCCCCAACTCA GCCTCCAGGACTCCGGCCTCAAACCCAAACCAGCTATGATGCCAAAAGGACAGAAGTGACCCTGGAGACC TTGGGACCAAAACCTGCAGCTAGGGATGTGAATCTTCCTAGACCACCTGGAGCCCTTTGCGAGCAGAAAC GGGAGACCTGTGATGGTGAGGCAGCAGGCTGCACTATCAACAATAGCCTATCCAACATCCAGTGGCTTCG AAAGATGAGTTCTGATGGACTGGGCTCCCGCAGCATCAAGCAAGAGATGGAGGAAAAGGAGAATTGTCAC CTGGAGCAGCGACAGGTTAAGGTTGAGGAGCCTTCGAGACCATCAGCGTCCTGGCAGAACTCTGTGTCTG AGCGGCCACCCTACTCTTACATGGCCATGATACAATTCGCCATCAACAGCACTGAGAGGAAGCGCATGAC TTTGAAAGACATCTATACGTGGATTGAGGACCACTTTCCCTACTTTAAGCACATTGCCAAGCCAGGCTGG AAGAACTCCATCCGCCACAACCTTTCCCTGCACGACATGTTTGTCCGGGAGACGTCTGCCAATGGCAAGG TCTCCTTCTGGACCATTCACCCCAGTGCCAACCGCTACTTGACATTGGACCAGGTGTTTAAGCAGCAGCA GAAACGACCGAATCCAGAGCTCCGCCGGAACATGACCATCAAAACCGAACTCCCCCTGGGCGCACGGCGG AAGATGAAGCCACTGCTACCACGGGTCAGCTCATACCTGGTACCTATCCAGTTCCCGGTGAACCAGTCAC TGGTGTTGCAGCCCTCGGTGAAGGTGCCATTGCCCCTGGCGGCTTCCCTCATGAGCTCAGAGCTTGCCCG CCATAGCAAGCGAGTCCGCATTGCCCCCAAGGTGCTGCTAGCTGAGGAGGGGATAGCTCCTCTTTCTTCT GCAGGACCAGGGAAAGAGGAGAAACTCCTGTTTGGAGAAGGGTTTTCTCCTTTGCTTCCAGTTCAGACTA TCAAGGAGGAAGAAATCCAGCCTGGGGAGGAAATGCCACACTTAGCGAGACCCATCAAAGTGGAGAGCCC TCCCTTGGAAGAGTGGCCCTCCCCGGCCCCATCTTTCAAAGAGGAATCATCTCACTCCTGGGAGGATTCG TCCCAATCTCCCACCCCAAGACCCAAGAAGTCCTACAGTGGGCTTAGGTCCCCAACCCGGTGTGTCTCGG AAATGCTTGTGATTCAACACAGGGAGAGGAGGGAGAGGAGCCGGTCTCGGAGGAAACAGCATCTACTGCC TCCCTGTGTGGATGAGCCGGAGCTGCTCTTCTCAGAGGGGCCCAGTACTTCCCGCTGGGCCGCAGAGCTC CCGTTCCCAGCAGACTCCTCTGACCCTGCCTCCCAGCTCAGCTACTCCCAGGAAGTGGGAGGACCTTTTA AGACACCCATTAAGGAAACGCTGCCCATCTCCTCCACCCCGAGCAAATCTGTCCTCCCCAGAACCCCTGA ATCCTGGAGGCTCACGCCCCCAGCCAAAGTAGGGGGACTGGATTTCAGCCCAGTACAAACCTCCCAGGGT GCCTCTGACCCCTTGCCTGACCCCCTGGGGCTGATGGATCTCAGCACCACTCCCTTGCAAAGTGCTCCCC CCCTTGAATCACCGCAAAGGCTCCTCAGTTCAGAACCCTTAGACCTCATCTCCGTCCCCTTTGGCAACTC TTCTCCCTCAGATATAGACGTCCCCAAGCCAGGCTCCCCGGAGCCACAGGTTTCTGGCCTTGCAGCCAAT CGTTCTCTGACAGAAGGCCTGGTCCTGGACACAATGAATGACAGCCTCAGCAAGATCCTGCTGGACATCA GCTTTCCTGGCCTGGACGAGGACCCACTGGGCCCTGACAACATCAACTGGTCCCAGTTTATTCCTGAGCT ACAGTAG Download Select all
CCDS ID	-

Protein Information

Protein ID	NP_001230017.1
Protein Name	forkhead box M1
Molecular Wt. (Da)	82611
Protein Sequence	>2305 MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPAGIKI INHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPGLRPQTQTS YDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCDGEAAGCTINNSLSNIQWLRKMSSD GLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYSYMAMIQFAINSTERKRM TLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLD QVFKQQQKRPNPELRRNMTIKTELPLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPL PLAASLMSSELARHSKRVRIAPKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEE IQPGEEMPHLARPIKVESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCV SEMLVIQHRERRERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYS QEVGGPFKTPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLG LMDLSTTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLT EGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ Download Select all
Length	748
Uniprot ID	P10144
Ensembl Protein ID	ENSP00000216341

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	742
S	Phosphorylation	704
S	Phosphorylation	689
T	Phosphorylation	649
T	Phosphorylation	611
T	Phosphorylation	596
T	Phosphorylation	649
T	Phosphorylation	611
T	Phosphorylation	596
S	Phosphorylation	331
S	Phosphorylation	331
T	Phosphorylation	658
T	Phosphorylation	665
T	Phosphorylation	620
T	Phosphorylation	627
T	Phosphorylation	605
T	Phosphorylation	612
T	Phosphorylation	757
S	Phosphorylation	768
T	Phosphorylation	719
S	Phosphorylation	730
T	Phosphorylation	704
S	Phosphorylation	715
S	Phosphorylation	755
S	Phosphorylation	717
S	Phosphorylation	702
S	Phosphorylation	777
S	Phosphorylation	739
S	Phosphorylation	724

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
6774	STAT3	26	NP_644805.1	in vivo	11861839

Pathway Information

No matching records could be found.

Structure Information

PDB ID	3G73
Resolution	2.21
Method	X-RAY DIFFRACTION
Chains	A,B
Molecule	Forkhead box protein M1
Model	View

Domain Information

ID	Location	Description
cd00059	236-311	FH
cl00061	236-311	FH superfamily
smart00339	236-315	FH
pfam00250	236-314	Fork_head
COG5025	236-313	COG5025
COG5025	235-312	COG5025
PHA03307	402-711	PHA03307
COG5025	223-345	COG5025

Ontology Information

HPRD ID	3271
Molecular Class	Transcription factor
Molecular Function	Transferase activity (GO:0016740)
Biological Process	Metabolism (GO:0008152); Energy pathways (GO:0006091)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO

Mechanism	Up-regulation
Biomarker	21281787
Drug Target	21281787
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism