CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
ALOX5	240	Arachidonate 5-lipoxygenase	10	5-LO; 5LPG; LOG5; 5-LOX

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24062003	2013	Cell line : - Source : Northwestern Memorial Hospital, Chicago, Illinois, American Type Culture Collection. Sample Type : CRC tumor and Normal tissue No. of Sample : 30 Stage : TNM Stage I-IV	Immunohistochemistry	Up-regulation	-	5-LOX expression in colorectal carcinoma is closely associated with lymph node metastasis, infiltration depth, differentiation degree and TNM stage.
18927292	2008	Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 52 Stage : TNM stage I-IV	Immunohistochemistry, RT-PCR	Up-regulation	-	5-LOX is up-regulated in colon polyps and colon cancer compared with normal colonic mucosa, indicating that 5-LOX expression is an early indicator of malignant progression.

Gene Details

Chromosome: 10; NC_000010.10 (45869624..45941567)
View Larger Image

Gene Type	protein coding
Gene Family	Arachidonate lipoxygenases
Description	This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Chromosome	10
Location	10q11.2
Start	45374176
End	45446121
Strand	+
Gene Sequence	>gi\|568815588:45374176-45446121 Homo sapiens chromosome 10, GRCh38.p2 Primary Assembly CCGGGGCCAGGGACCAGTGGTGGGAGGAGGCTGCGGCGCTAGATGCGGACACCTGGACCGCCGCGCCGAG GCTCCCGGCGCTCGCTGCTCCCGCGGCCCGCGCCATGCCCTCCTACACGGTCACCGTGGCCACTGGCAGC CAGTGGTTCGCCGGCACTGACGACTACATCTACCTCAGCCTCGTGGGCTCGGCGGGCTGCAGCGAGAAGC ACCTGCTGGACAAGCCCTTCTACAACGACTTCGAGCGTGGCGCGGTGAGCGCGGGCGGGGCACGGGTGGA GCGCGGGCTGAGGTGCGTCCGGGACCCGGTTTGGACGGCAGAGGCCTGGGCGGGGGCGCCGAGGGCCCGT CGGGGCGGCCCGGACAGGACTGGGGGTGTCCAGGACCCTGTCAGGGAGGGCAGAACTGCGGTGGGGCGTG CCCTGGGCTCCCAGTGGCCGGTGGGTACCCTGGTGGGCAAGCGTCCAGGACCCCTCGCGGCGGCCGCGAC CCCTGTCGGAAACGGAGACTTCCCGCGTGCCGCCTGCAAGGCGTCTTCCCTGGGAGGAGAAGGCCCAAGG TTTCCCCTCCACTTCAAGATCTGGGCTCCGAGGCTCCGGAGCCCCCTTCACTGGGCCGCGTTTCTTGTGC CACCTCTTCCTTAGGCTCCTTCTGCAGGTCGCACAGGGAGGGAGAGGCAGATGAGTCATGCTCACAGAAC TCTGAGGGCACCTCGGAGCAGCCAGCTGTGAGCCGTGGGGAAGGGTGCACGTCAGCGGGTCCAGAGGCCT GAGTTCTGTCCAGACATGACCACCAGCTCACTCTACCGTCTGTCTGGGCCTCAGTTTCCCCAGCTGAAAA TGGAGGGTTGGCTTCAGTCTGGTCCATGAGTCATGGGTGAGCCCAGGCCCATCTGGTGGCTCAGACGGCA CCTGGGCAGCTTACATTCTCAGGACAGTCCCCAGAGGAAATTAAAGGGAAGGAACAGAACCCAGGCCAGG AGAGGCTTTTCCTAAATGGAGGGGCTGCACTCCCTCCCAGCAGAATGTACACCAGGGAACACTTCCACGC TAGGTGTGAGGACGCGAGGGAGCCCTCAGCATTTGGAAGCTAGTTCCTAATGCTGATCTGGACCTGAATT CCAGCCCCACGACTCTTTTCCATGAGCATGGGCAGGTCGCAGTTCTCACTGAGCCTTTAATGAAGTGCCT AATCCAGTACCTGGCACAGAGGAAGCGCTCCGTAAATGACTGGTAATAGTCCCAGACATACTGCAGGTGC GCAGGGAATATCAGTTCCCTTCCACCCCACCCCAGCTCCTAACTGGACCAAAAAGATTTAGACTTTACCA AGCTGCCTTCTCACCATTTAGTTTATTATTTGATCAAACCTTGTGAAATTGCTCATAATGGACAAATACA ACCGGCAAGTTCATGTTTCAACTGATTACTCTTGGATAAAATTTGTGTTTTAGGTGTGCAGAGCCTAAAG TAAGTAAAAACTACTCTTTTTCTGGATTCCAAGCTCTCCATGGGCTCGATTCCTATCCAGGAGCCCATAC CCTCGCTGTAGCACGACATGGCCCTCAGCCAAGTTCACTAGCATCCTGGCTTGAGCTCCCTTCAAGAAGA GTTAGGTGTTGAGTACAAGAGCAACCTTCAGTTGCTTAGTTGCCCCAGTCGGGGAACTGACCCTGAGGAC TGCGGTGCCCTGGAGTTAATGTGTCGTCCATTTAGGGTGATGGCACCCTCTGCCATTTCTGACGCACCTT CATTTACTTCCATTATTTCATGGATTCCCCACACCTGGGGGAGAAGGACAGGGTACAGGCTACTTCCCCT TTGTAAGTGCTTCCTCCTCCCCATTCTCCTCCACACATCATAAGGTTCTAGAAGCACAGGCCATTGGTGT GCTCACACTGCACAGCACGGGCACCCCGTGTGTGCTTTCCTCCTGCAGGGGACATGATAACGTGGCCATA GCGGGCTCTTCGGACAAAGAGTGAAGGCACTGTTTTGTCCACTATCTCCCTCTCTCGGTCTGTCTTCCCC TACCCTGAGAAGTCATTCAAATGACATTATAATTAAACACCTCAGCCGGAATCCCAGGGGCAAATTTCAG GAGAGATTTGCATGTCACATTTCCATTGGGTTGAGAGGGCTATAAGTCAGGGGTGGGGCGGGGGGTGGTT GGGGGTGGGGGCTACCGCAGGGTGGGGAACCAGCTAAGGCTGAAAGTTTCCTTGAAAAAATCAGCTTTTG AGAAAGTTCCTGTTGATGCAAAGTTACTCAACACTTTCTCTTGCCCAGCCCAGAACTACTTCCTCATTCT CCCAGCTTGGTATCTGTAAAGACAATCATCCTTTTTGGGTAAAGGTAAAAGAGAAACCCTAGAGGAAGTA CTTGCTGAGAAGACAAGGTTATCCCATTTTACAGGGAAAAGTGTTAAAATCTGTATTGTTAACAGTAGTA ACGATAACAATAACAATAAAGGTATTTCCACACAATTTAATCATTTCCAAGTTATTGGCAGGTCAACACC CCCCTCCTCCAGGGCATAGTTCAGTCAAATAATGGACAGGACTGATTTTTTCCTTGATAAAGTGAGTCAC AGGTCCCTTGTTATTCTCATCAGAGTTCCGCATAGTGATTCAGTCAGGACTGGGAATCAAGTCCTTCGCA GGTGGGATTATCCTATAAACGGTTGTGTCTTCCTTGGCTCCTCACTGTCTGCTGGAGAAAGCCGGGATCC TACACAGAATGGCCCTGTTTCCAGAGGCTAACCCAAGTCTAGGCAAATTTAACAAGTTGATTTATTTCTT TAACTCTGTAAATTTAAAGTAATTCAGATCGGATACGATAACTGTAACAGATCTGAAGATTTCTGAGAAA TCTTAGTTGGCCCATTTCATTCTGTGCTGGTACTTTTAAGAAAGCTAAGGGCAATAGCGTGGTGTTTAAT ATATGATACTTGAATATGTTCAACAAGTGTAGAAAAGTGTTATAATGATTCATGCTTCTTAAGTCAGTGA GTATTCTTACATTCATGAAAAATTAATTCTAGAATACCTCCTTCTTGTGAATGGGAATATATTAGTGGAG CATAAATATTTCTTTGGTATGACCCTCAATCCGTCTCTCATCTCCCAGTCTCCCCCTCTGAGCCATCTTT TCCCTACATTCTGCCCCCTCTTCTGCCTCCTCTTCCTTCCCCTGCTCCCAGTTCCCTAAATGCCCCCCGT TTCTGCTCTCTACCCTACAACTCTCCCTTCTTTTTTGCTCTGAATTTTCCTCTACACTCTGTCTTCCAGC CACCTCTCAGAGGCCCCTTCTCTGCTCCCTCAATCTCCGGCTCTCTGTCCCACATTTTCCCCCTTCTCTG CCCCTTGGTCTCCCTATCCACTACCCCAATCCCTCTCTCCGTCCCTTGTTTTCCTCAGCTCTTCCCCATA GCCTCCCCCTCTCTCATCCCGAGTCTCTGTTTTGTCTGGCCCCCAATCTTCCTCTCTGCTCTACAGCTTC CTCCTCCCACAGCCCCTCATTAGTCCCCCTCCAAGATGGGTAGTCTGGGGGTGGGGCACACATCCTTGCT TCCGCAGAGAGATCCGTCTCCCTGTCCCAGCAACAGCAGAGATCTGATGAAAGACAGATGAAAACTTTCC TAAAATGCTGATAGAAAGCTCACATGAAAACTGACCAACTGACTCTTTGCCGAAATATTCAAAAGCTTTA AAACTACATATCCAATAAAAAGTTAAAAGCAACAAGCAAAATCAGCAAAGTGGCCCCTTGTGAAATGAGG CCGGTGAGTTGCAGGTTTCCCTTGTTTCTCTCCAGCATCTGCACCACCACGCCACCCACTTCTGTCCCCA GAAACTGTGTCCAGCCTTCCTCCTCCCACGTGTGAATCCCCCGGGGACCCTGCCCTCCCAGTTCCCCACA TCTGAAATGTGCTACCCATGCCCATCCTCCTACTCATCTGCCCTCTGAAATCTGATCAGCCCCTAAAAGC TGCCTGAAATACCCTCTTATGAAGCTTTTCCCTGTCCTTCCATGCCACTCCACATTGCCCCTTTACACTC CATCCAGGGTACAAACCAGGGCTCAAAGCTGGGCCTTCTAGCTTCCGGTTCAGGGCTTTTCTCAAGATGT GGCCTTGGGGAACTGTGGGAGGAACCTGGGCTTGGCCATCACACAGGTGTAGGTTCTGATCTTGAGGCCA CCATTGCTCTCTGAGCCTCAGTTTCTATCTGTAAAGCAGGATAATCACTCGCTCGGCCATTCCCAGGCCC AGTGCTTCCTGAGGGCCTGTTGGGGGGTGTCCACTGTTGATAGTGCCCACCATAATTCAGTGTGTCACCT GAGAATTTAATGTGTCACAGCAAATAGACAAATATAGCATCAGCCCAGTGTACTTGGCCCAGAGAGGAGG GAGGAAGGTGGCCATTGTAGTTCCACAAACCTTCCGAAGATATTTTGCAGTTTGACACATGTGACCCTGG TATTTTCCTGGAAGGAGGCCTTTATCTGTCATTCTTCCATTAGTGGCCCCTGGGATGTTAGAACCACAGC CATCAAGCTTTGTCTTTTACTCCCTGAGTTGGGTCAAGGCTGGAGCCCTCTGCCCCTTGTTCACCTCTTA TCATATTCAGGCTTGAAGCCAGCACCAGGAAAGTGGCTGGGCTGGCCATAGACCAGCCAGACTGCAGGCC TGGCCCCCTCCTGCTGTGGAAGTCCCTGTCAGATGGCAGATGGAGTCCTTGTAAATCTGCCTAGTGATTT CACCCCAAGTGAAACTCAGGGGCTCTCCACCAGGTGCCTGCAGGTGTAGGTAGGGCAGGGGGCCAGGAGT GTCCCAGTCCCCTGTGACTGCACCACAGGTGTGCTGGAGGGTCACCCCACTGTCCACTCCCTCAGAGAAG CTGCTCAGTCTCTTCGTGTGGGTCGTCACCCCCAGGTAGACATCGGGCCCTCCCTGTGGGACCTGCCCAG TCCTGGAATGCCTCCTCAGCCCATCTCCCTCCCCTCTTAGTCCAAGGTACTGGGAGCCTCCCTCCCATGA GAGTGTCCCTGTTAGCTCCTCCCACCCCACCCCAGCTTTCCTGTCATCTATCCCCTGGGGACACCTTCCT CCCTCTCCAGCCCCTCAGAGCCATAGGAAAGCTACTTCCCCTGCAGCAGCCACACTCAGACCAGGCCCGG GCCTCTGGTGGCCGCCCCTCAGTCCTCACCGCACACAGACTTGCTCTGCCTGCCCCACCAGCATTCAGAA TGCCTCCCACTCTCCCTCTGTCCTCACAGCCCTGTCTCCAGCCTTTCAGGAGTTCCTTCTGGGCTTTGAG TGAAGGAGTTTGAGGTCACAGGTTCAGTTTCCTCCTCCCATGTGTGCTCCAGTTACTCGGATTGGCACAT GTAGTCACGAAGTGGCCGTGACGCAGGGGCCCATGCTAGCTCACAGGCGGTGTGGGGCCTGGTGCCCTGC AACCCCCTGGATTCAGGAAGGGGCACTGGTGGTTCTGATGCACACAACCGGTGGCCTGTGCCTCTGGAGA AAGGAGGCCACCCAGGATGGTGTCATTTCATTTTCTCAATGGTCCTGCAAGTGAGGGGTATCTCCTTTGG GTAGATGAAGAAACAGCTTCAGAGAATGAAGCAATGTGCCCAGGCCATCCAGCTACTTGCCTGAAGCTGG GATGTGAATTCAGAGCTCCAGACCCCAGGGCCCACCGAGCCTTCTACCCCTCACTGCCCTCTCCCCACTC CTCGGTGGGATCAGGAATCTCTGTCTTGGCTCACAACCTGCAGCTAAGGCCTCTGTAAATCCCTGTGGCA TGCAGGGCCTGGCGTGGGGCAGGCCCGACGCGTATCCAGTCCTGGGCCACTCAGCCCCCACTCTGCTCCT CCAGATGGGCCCGAGCCCCTGAGATGCTGAGACTCCTGTCCCATCAGAACCTGCCCACCCTGTCCATGAT GGGCGAGGCCTTGTGTGTGGCCCTGCTCTCCTGAGGACAAGCTGTGGCAGGAAGGCTTTCTCAGAGGTGG CAGATGAGGCTGATACTCTCCCTGCAGGAGGGGCATTGTCGTGGGGCCGAGGCTGGTCCACATGTGGCTG GACCCAAGACATGTCATCCCACCACATGGGCCTGGCTCCTCTGTCATCAGAAACTGTTCCTAGGGCCTCT GGCCTAGACTACAGAGCACAGGGAGGAAGCTTCCGCTTTCTGACCACAAGCGTCTGGCCTCAGCGTCAGC CACCCCAAACTGCTCACGGTATTCAGAGCCAGGAGGTTTGTGGAAAACACTCAAGTTCCCATTCCTCTTA GGAAGCCCTCCAGGGGTCCTCCTGGCAGCTTGGAGGCAGGGCATGGAATGGGGATGCCTGCGCTCGCACA AAGGATGATACCCCTCGCCCCTTCCACTTTGCCATCATGCTGAGAACTCTAGGTTCTGCCGCCAGGGATA AAGTTCAAGGGTTGATGAATCTGGCTTAGAAAGTGCCTTGCAGGGGCCAGGCACAGTGGCTCATGCCTGT AATCCCAGCACTTTGGGAGACCGAGGCAGGTGGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCA ACATGGTGAAACCCTGTCTCTACTGAAAATACAAAACTTAACCAGATGTGGTGGCAGGTGCCTGTAGTCC CAGCTACTTGGGAGACTGAGGCAGGAGAATCACTTGAACCCTGGAAGTGGAGGTTGCAGTGAGCCGAGAT CGAGCCACTGCACTCCAGCCTGAGCAACACAGTGAGACTCCACCTCAAAATAAAAAAGAACATGCCTTGG AGGGCATCGAGTCCGGGGCTTTCCAAACCTGCTGGTCATCAGAATGCGTGATGCAATGCCTGAGCCTCTC ATCCCAACTTCCTGTCTGCCATCCATTGCTGCAGAGACAAAAGCCCTCCAGAAGCTATGGCTGTTGCCTC AGAGCCGCCTGTGTCCTGGAAGCAGGAGCCTGGCAGGGAGGGGGCCAAGCAGCCTTGTCCCAGAGGCCTG GGCAGCTGCGCTGTACACAGCCTGGGGTGGTGCCTTCTAGCTGCAAGGCTAGCCTCACCCTGCCACCAGT AATGCCACAGGTGCAGCAGAGCTGCTTGGTCTCACTGTTCTCTGGGCATCACCATGCAGCTGTGAACTGC AAATGTCCCAGGACGACTCGAATCCATGCAAGCTCCCTGTATCTAAGCCTCACCATTTTCACTCACTTAT TATCCCCACTGAAAACTGGAAAGAGAGGAAGTGGCTATGATGGAAAGACCTGGGGTGTGACTCCAGCTCT GCTGGCAAGTGGCAGAGGTGGGAGTCACTGAGCCTCGCTGTCTTCATCTGTGGAAGGGGTGGTAACTCCC CTGCACTCCCAGAGTCATTGTGGGGATCCACTGTCAGCAAGCCCATCTCCAGTTGTAAAGGTCTCCCACA AGGCTATCCCATGTGGGGGCAGCTGCGGACCCTCACTGGGCACAGCCTCGCAGGTGCAGGCATGAGCCTG GGCATCTCCCCATCCTCCAGCCTGAGCTAAGTGCAGTCAGCAGGCGTTGCCCTCTGAGCAGCACAGCACC ATCCTGGCTCACTGGATTCTCTCTCCTCAAGGGCAGGGCCCAGGATTTGTCCATTTCTTTCACCTGCCTG GGTCGTAGCACTGAGCCTTGTCAGGGGCAGGCCTTCAGTGAATGTCTTGGGTAAATGAATTCAGGAGTTC ATTTAAGGTGTTCATGAAGAATCTTGGCTCCATGAACTGTAGTGGAGGCAAAACTCCACCTCTTCCCATT TCAGCTAGGTCTGAGAATCGGCATAAGACAGATTCATGGGCGAAAGCCTACAGATTTCTTTAATACAAGT TGTACGTGGCATGGGAGCCCTCTTAAAAAGATGAAGACCCCAAGAAGCAGTTAGAGTCAATCCCCCTTAG ATACTGCATTGAATGAATCATCGTGAGATGTGATAAGGCCAAGGGGCTTGGGCTAGGGCAGGTAACTGGG CAGGGAAGTGACTCGGGAGGTAAGCGTTCATTGTACAAGATCTGTTTGTATGGATTTCCTTTGGCTTCAA CTTCCCAACCTTGATGAAAAGAGTGTTACTTTCCTTTTGGTATAGTGAGGACATCTTTCATAGGGGACTT TCATCTCCTGCTTCTAAGAAACAGCACGAATGTCAGAGTATCTTGCACCTGCTGTTTTTTTAAGTGCTTT TCATTCAACGTAGTCCCTGTGCCACAGCAGCATACCTTGGGGTGACAAATTCTTAACACCTCCAGAACAA AGGCTCAGGAGACCACGCATGGCCTGATTGCCTGTTCTCCTTCCCAGGTGGATTCATACGACGTGACTGT GGACGAGGAACTGGGCGAGATCCAGCTGGTCAGAATCGAGAAGCGCAAGTACTGGCTGAATGACGACTGG TACCTGAAGTACATCACGCTGAAGACGCCCCACGGGGACTACATCGAGTTCCCCTGCTACCGCTGGATCA CCGGCGATGTCGAGGTTGTCCTGAGGGATGGACGCGGTGAGCAGCTCAGGCCCCTTCTGCCCCGGGCTTC CCAAGAACCGAAAGTTCTTCCTGTCCTCAAAGCACTGTAGTCATAGGAGGAATGACACTGCTGTGCAGGG GCGGGAAGTGGGAGGGCTCTGCCCTGTGCCTCGACACACCTGCAGGAGGCATGACTTTCCTTGGGATTCT TACAAGCCCCTGAGGGTGGAGCGGGTGGCCCCAGGCCTCACTGTCGTCATGTCCTCACTCTGCGCTACAG TTCTACAGGGGAGGGTTGTGCCCCTCTTTTTGTCAGTGGGTAACTAGGGTCCATACAGGCAGATACCTAT GGGACATGCCCCTGGATGGGCACTTCTCTAGTTGCCAGGGTGTGGCATCACTTTCTAGTTCATAGCCTGC CCTCCGTGAGATCACAGTAGGGCTCAGGCAAGCTCAGGGTGCCCCATGTGGGCCTAGGGAGGGAAGGGGT GGACAAGGAGCACCCCAAGTGCCAGCTCTGAGGAGCCATGGACAAGCCTGCAAATCACAGTTACCAGTTC TTCAACCCGAAGTCTCACCTTTCGCTGAAAGAAAGAAGAACCTCAAATCTGTTCCCCTTACTAAGATGCC CAGATGTGCAGACCCCAGTTAGGAGGCCATTCTTTGTTAGGGACACACAGCTGACCTGGTACAGAGCATC AGAGACGGACGCAGGCGTCAAGGTCAGCCAAGGCTCCCTGAATGAACCACCTTGCATACCCAGCCTCCTA GTGTGCCTGGCAAAATCCTACCTCACTTCGAGTCATAACCCTTCAGCTTGCTCTCAGTTTAAACCTGGAA AGATAAGCCTTCAAAGGCCAGGCAGCCACCGTAATAAGAGAAAGCCACTGCTTCTGCCATGACAGCGTCA AACTCTTTCTCTTTGCCAAGTTTCCTGTAGCTAGTGTGTTCTTCACGAAGTTTGGTGGGGTAGGTAGGAA GAGATGACTGTTACCCCCATTTTATAGCTAAGAAAACTGAGACAAAGGAGAAAAAAGTTATTCTGTACCT GCTGTTCTTAAGCTACCAGGCCACATCCCATCGTTTCTGATGTGGAATTTGACTTAAGAAACCAAATTTC CAGAATATTTCTGAACATGGAGTTAAGAGGATTTTTGTCCCCCTACCTAATGACAGGAAAAAAAATCACA AAGTTCATTTATTCCTGTGGTCAACAGAATGTGGAAGGTTGTGGACAGGGCACTTCTCTTTTTCTGGTAG TTAGAAAATGCTGGCTCTGAAACTCCCTCCTGCACATCTACCCAAGGTCTCGGTTATGAAGCCCTTCTTC CTGCAGACCCTTCAGCTCATCTTGGCAAAAAACAGATGGTACACTAGGATGAGGGTTTAACAAAGGGGCA TCACAAAGGTGTGGGCCCATGTGCAGAGGGACCATGCAGAGTGCGGGGCCATCAGCACCACTAGTCCTGA TGCAGGGGGAGGGGGAAGGTTGTGGGAGTAATGCAGAAGTATCCTGGAGACAGCACCCTTGGAGGAGCTG CGGCCCTCAGTAGAAAGGTTCTGGGGAGTGATTGGCCTCTCCTTCCTCTACACATTCCCTCCTTTCTGGT CAGAGTTCCCAGTGGAAAACCCATTGAGGCATCTCATTCCAATCACTTTCAGGGACAGCACAGGTTGGAG GGTGAGCATAGAGAAGCTGTCCAGCAAGTTCCATTCTCTCTACTGCTGTAAAACCAACCTCCTTGGTAAC TTTAAACAGCCATTTAATTTTGTTCATGCTCTTGCAGGTCAGGAATTTAGGAAAGGCTTCACTGGGCAGT TCATCTGTGGCCATGTAGCATCAGCTGAAGGGGGCTGGGCCTTCTTCTGTCATGTGTCTGGCACCTCTAG GCTCCTTGGCCTCTCTGTCCATATGGAGTCTCATTCTTTAAGGCTTCTCACAGAATGGTGTCCTCTGGGT GCCTGCATTTCTTACATGATGGCTGGCTTCCAAGAGCAAGTTTTCTAAGAGACAGAAAGTGGAAGCTGCC AATCTCTTCAGGCTTGGGCCTGGAAACTGGCACACTGTAACTTCCATCATATTCTACTGGTCCAAGCAGT CACAGAGCCCACCCAGACTCCGGGGGTGGGGGTGGGGATGCAGACCCCCCCATCTCTCAATGGAAGGAAT GTCAAAGAATTTGTGGCCTATTATTATTATTATTATTATTATTTTGGGACAGAGTCTCACTCTATTGCCC AAGCTGGAGGGCAGTGGCACGATCTCAGCCCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTG CCTCAGCCTCCTAGGGAGCTTGGTTTACAGGCTCCAGGTAGCCACCAAGCCTGGCTAATTTTTGTATTTT TACTAGAGAAAGGGTTTTGCCATGTTGGCCAGGCTAGTCTGGAACTCCTGACCTCAGGTGATCCACCCGG CTCGGCCTCCCAAAGTGCTGGGATTACAGTCATGAGCTACCATGTCCAGCTGTGGCCAATTATTAATCCA CCACATGGCAAAACAACCAATCCCTTGAACAACCTGGAAATGAGGGGGGCCAGCCTACAAGTGATTCAAT TACTCACCATATGATCACCCCTTAAATCTAATATTTCACCACTACACCTTGGGTGAACATGAATGTCAGA GGGCCATTACTGTGGCCCCACAGATCCAGAGCATCTGTGTGAAGGGACAGCTTCATTAAGGCACTGTGTC AGTCCTTGGAACCTGCCCTGCTGAGCTCTTCTGCCGTCAGTCCAGGCTTTCTCATCCTGCTGTGCTCCCA GAACTTCATCAGCCATTGGATAAATTCTTCAAACACCTTCGGGACCAGGGGAGACAGAACTATTCTCTTT TTGAAACTTGGCATGTTGCAATTCCGCATGTACTGACTTATTCATACCAGTGAAACTGAAGAGATCCAGC TCCTCAGAGTCAAGGTGCCCAAGAGATTAGCTGGTTCCTTAAGGTAGATAAGAGATGATGAATGTTGAGT GCCTCCAGAATTACCCCCATAGCCAATGATAACAGTTATTGTCACCATTAATACTCAGCTTGCCTTCTGT GGCCTCAAGCCTCCCCTCCTGGCTGGCTTTACATCCCCAGGGGAGGATGCAGAGGTATCCCGTTAATATT CCTTTTTGGACCCCAGTTCCAAGCTCAAGGATGAAGATGTCTCAGCCTGGAAGTGCTGTCGGGTGGACAG CTCAGAATGTGGCCTGAGTGTCATCTGAGAACTAACTGCGTCCAGGTCTGCAATTAGATCAGTACAGAGG TTGAAGCCTATAGTTCCAGCACTTTGGGTGGCTAAGGCGGGAGGATTGTTTGAGTCTAGGATTTTGTCAC AAGCCTGGGCAATGTAGAGAGACCCCATCTCTACAAAAAAAATTGAAAATTAGCTAGGGGCCGAGGCGGG TGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTAAAACCCCGTCTCTACTAAAAATAC AAAAAATTAGCTGGATGTGGTGGTGGGCAACTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATG GCGTGAACCTGGGAAGTGGAGCTTGCAGTGAGCTGAGATCATGCCACTGTACCCCAGCCTGGGCAACAGA GCAAGACTCTGTCTCAAAAAAAAAAAAAAAATTAGCCAGGTGTGGTGGTGTGTGCCTATAGTCCCAACTA CTTAGGAGGCTGAGGTTGGGGAATCACTTGAGTCCTGAAGTTCAAGGCTGCAGGGAGCTATGATCATGCC ACTGCACTCTAGCCTGGGAGACAGAGGGAGACCCTGTCTCTTAAAAAAAATAAAAATAAAATAAATACAA AATAAAATACAAAGACTCAGAGGAGGGGTTTTAGAAACTTTTATAGCAACTTAACAGAACAATTTTGTGA CTTTTGCACCTAATAAGAAAAAAAAAGACTTGGATTTTGAATATCTTTGGGTTTTTAAAATTTCATTTTT CTAGTAATTAATTTTTATTATATTTTACAAAAATATAATAATCTGTGTTGAAAAGTAAGTTTTAAAACAC AATGCTTTACCACGAGAGCTAGAGAAACTATTCCAGGACCTGTTTTCAGGAGATCTGGGCTCCCCCTATT CACAGCTCTATGGGCTGCGTTCACAGGCTTGGCCTTAAGCAATAGTTTAAAGAGTGGTCATGATATGACC TCATCTGCTCTAAAGGCTCTGAGAAGCAGCCCCGCCCTTAGCTACCTGCTACCTGCTCCAACTCCTGCAG TGAGAGACGGCAGCAGGACAGGCTGAGAGATAAGATGCTCTCAGAGCTAGGCTTAGAGGGAGGAGCAGAA CCCTCAGGCCAGTGATGACTATAGGCATAATGATAATGATCATTGTTCCCATCCATTGGCATTTACTGCG TGCCAGGCGCCGTGTGGAGGGCTTTCCTGCATTCTCTCCCCAAATGCACACCATGACCCGGAGAAGTAGG CATTATCATCTCCATTTTACATGTGAGGGGGTCAGGGCAACTCTTGGTCACACAGCTTCAGTGACAGAGC CCAAGTCCAAGCACATGTGTCTCTTCTAAAGCCATCTAGGACACTGCACTCTTTTAGAATGGAGCTCATT CTCAATCCTCTGTGTAGGCACGACAGGAAACCGGGTTGTGTCATCGTCACACATTTCTCCATGAAACAAT GAAATGGACTTAGAAACATAAGAGCTGTGAGAACTGCTGCTCTCACAGGCAACACTAAAACCCAGAGTGA ACTCCCGTTTTTGCTCAGTATAAGAATTTCAGAGAAGAGGAGTAAACTATTCTGCAGTGATTTAAAGATA CCCACCAAGGGCCACGAAATGCCTTTCTCCTGGAGCAAAAAGGCAGCTCTGCACCAGGGGCCCTTAGGTC CCTGAAGAGTCTTGAGGGGCTGAGTGGAAGGTTAGGACCTCAAGTGGAAATGCACACGCAGGCCAGAGTT AGGCATGTACTGTGCCTGCCAAGCCCAGTGAGAACCAAGCCTGGCTCTTGCATCTGAACATGATTCTCTA AGCACTGAAAGGCAGGGGCCCCAAGGCTTGCTGAGTGAGTGGGCAAGAGGATGAGGAACTGGATTTGGCT TTTGTAAAGTGAGTGGCTAAGAGCACAGGAGTTGAGTTTTATGTTGAAAATTCACTAATTCAGACTGGTT CCAAGATGGCCGAATAGGAACAGCTCCAGTCTACAGCTCCCAACATGAGCAATGCAGAAGATGGGTGATT TCTGCATTTCCAACTGAGGCACTGGGTTCATCTCACTGGGGATTGTTGGACAGTGGGGGCAGAACAGTGG GGGCAGCCCATTGAGTGTGAGCATCACCTCACCTGGGAAGTGCAAGGAGTCAGGGAATTCCCTTTCCTAG CCAAGGGAAGTGGTGACGGACAGCACCTGGAAAATTGGGTCACTCCCACCCTAATACTGTACTTTTCCAA CAGTCTTAGCAAACAGCATACCAGGAGATTATATCCCATGTCTGGCTCGGAGGGTCCCATGCCCACAGAG CCTTGCTCATTGCCAGCAAGCTCGAACTGGGTGGAGCCCATCGCAGCTCAGGAAGGCCTGCCAGCCTCTG TAGACTCCACCTCTGGGGGCAGGTCATAGCCGAACAAAAGGCAGCAGAAACCTCTGCAGACTTAAATGTC CCTGTCTGACAGCTTTGAAGTGACTAGTGGTTCACCCAACATGGAATTTGAGATCTGAGAAGGGACAGAC TGCCCCCTCAAGTGGCTCCCTGACCCCAGAGTAGCCTAACTGGGAGGCACCCTCCAGTAGGGGCAGACTG ACACCCCACATGGCCAGGTACACCTCTGAGACAAAGCTTCCAGAGGAGCAATCAGGCAGCAACATTTGCT GTTCAGCAATATTCGCTGTTCTGCAGCCTCTGCTGCTGATACTCGGGCAAACAGGGTCTGGAGTGGACCT CTAGCAAACATCAACAAACCTGCAGCTGAGGGTCCTGACTGTTAGAAGGAAAACTAACAAACAGAAAGGA CATCCACACCACCAAAACCCCATCTGTACGTCACCATCATCAAAGACCAAAGGTAAATAAAACCACAAAG ATGGGGAAAAACAGAGCAGAAAAGCTGAACATTCTACAAATCAGAGTGCCTCTCCCCTTCCAAAGGAAGG CAGCTCCTCGCGAGTGGTGGAACAAAGCTGGATGGAGAATGACTTTGACGAGTTGAGAGAAGAAGGCTTC AGATGATCAAACTTCTCCCAGCTAAAGAAGGAAGTTGGAACCCATCGCAAAAAAAGCTAAAAACCTTGAA AAAAGATTAGACGAATGGCTAACTAGAATAACCAATGTAGAGAAGTCCTTAAATGACCTGATGGAGCTGA AAAACATGGCACGAGAACTATGTGACGAATGCACAAGCTTCAGTAGCCGATTCGATCAACTGTAAGAAAG GGTATCAGTGACTGAAGATCAAATGAATGAAATGAAGCGAGAAGATAAGTTTAGAGAAAAAAGAATAAAA AGAAATGAACGAAGCCTCCAAGAAATATGGGACTATGTGAAAAGACCAAATCTACATCTGATTGGTGTAC CTGAAAGTGATGGGGAGAATGGAACCAGGTTGGAAAACACTCTGCAGGATATTATGCAGGAGAACTTGCT CACCCTAGCAAGGCAGGCCAACATTCAAATTCAGGAAATACAGAGAACACCACAAAGATACTCCTTGAGA AGAGCAACTCCGAGACACATAATTGTCAGATTCACCAAAGTTGAAATGAAGGAAAAGATGTTAAGGGCAG CCAGAGAGAAAGGTCAGGTTACCCACAAAGGGAAGCCCATCAGACTAACAGCTGATCTCTCGGCAGAAAC CCTACAAGCCAGAAGAGACTGGGGGCCAATATTCAACATTCTTAAAGAAAAGAATTTTCAACCCAGAATT TCATATCCAGCCAAACTAAGCTTCATAAGTGAAGGAGAAATAAAATCCTTTACAGACAAGCAAATGCTGA GAGATTTTGTCACCACCAGGCCTGCCCTAAAAGAACTCCTGAAGGAAGCACTAAACATGGAAATGAACAA CTGGTACCAGCCACTGCAAAAACATGCCACATTGTAAAGACCATCAATGCTAGGAAGAAACTGCATCAAC TAATGAGCAAAATAACCATCTAACATCGTAAAGACAAGATCAAATTCACACATAACAATATTAACCATAA ATGTAAATGGGCTAAATGCTCCAATTAAAAGACACAGACTGGCAAATTGGATAAAGAGTCAAGACCCATC AGTGTGCTGTATTCAGGAAACCCATCTCATGTGCGGAGACACACATAAGCTCAAAATAAAGGGATTGGAG GAAGATCTACCAAGCAAATGGAAAACAAAGGCAGGGGTTGCAATCCTAGTCTCTGATAAAACAGACTTTA AACCAACAAAGATCAAAAGAGACAAAGAAGGCCATTACATAATGGTAAAGGGATCAATTCAACAAGAAGA GCTAACTATCCGAAACGTATATGCACCCAATACAGGAGCACCCAGATTTATAAAGCAAGTCCTTAGAGAC CTACAAAGAGACCTAGACTCCCACACAATAATAATGAGAGACTTTAACACCCCACTGTCAACATTAGACA GATCAATGAGACAGAAAGTTAACAAGGATATCCAGGAATTGAACTCAGCTCTCCAGCAAGCGGAGCTAAT AGACATCTACAGAACTCTCCACCCCAAATCAACAGAATGTACATTCTTCTCAGCACTGCATCACACCTAT TCTGAAATTGACCACATAGTTGGAAGTAAAGCACTCCTTAGCAAATGTAAAAGAACAGAAACCATAACAA ACTGTCTCTCAGACCACAGTGCAATCAAACTAGAACTCAAGATTAAGAAACTCACTCAAAACCTCTCAAC TACATGGACACTGAACAACCTGCACCTGAATGACTACTGGGTACATAACGAAATGAAGGCAGAAATAAAG ATTTTCTTTGAAACCAATGAGAACAAAGACACAACATACCAGAATCTCTGGGACACATTTAAAGCAGTGT GTAGAGGGAAATTTATAGCACTACATGCCCACAAGAGAAAGCAGGGAAGATCTAAAATTGACACCCTAAC ATCACAGTTAAAAGAACTAGAGAAGCAAGAGCAAACACATTCAAAAGCTAGCAGAAGGCAAGAAATAATT AAGATCAGAGCAGAACTGAAGGAGGTAGAGACACAAAAATCCCTTCAAAAAATCAATGAGTCCAGGAGCT GATTTTTTGAAAGGATCAACAAAATTGATAGACTGCTAGCAAGACTAATAAAGAAGAAAAGAGAAGAATC AGCTCTCCCTCTCCCCTCTCCCCTCTCCCCTCTCTCCTCTCCCATCTCCCCTCTCCCCTCTCCCATCTCC CCTCTCCCCTCTCCCTCTCCCTCTCCCCACGGTCTCCCTCTCCCTCTCCCCACGGTCTCCCTCTCCCTCT CTTTCCACGGTCTCCCTCTGATGCCGAGCCAAAGCTGGACTGTACTGCTGCCATCTCGGCTCACTGCAAC CTCCCTGCCTGATTCTCCTGCCTCAGCCTGCCGAGTGCCTGCGATTGCAGGTGCGCACCGCCACGCCTGA CTGTTTTTCATATTTTTTTGGTGGAGACGGGGTTTCGCTGTGTTGGCCAGGCTGGTCTCCAGCTCCTAAC CGCGAGTGATCCGCCAGCCTCGGCCTCCCGAGGTGCCGGGATTGCAGACGGAGTCTCATTCACTCAGTGC TCAATGGTGCCCAGGCTGGGGTGCAGTGGCGTGATCTCGGCTCGCTACAACCTCCACCTCCCAGCCGCCT GCCTTGGCCTCCCAAAGTGCCGAGATTGCAGCCTCTGCCCGGCCGCCACCCCGTCTGGGAAGTGAGGAGC GTCTCTGCCTGGCCACCCATCGTCTGGGATGTAAGGAGCCCCTCTGCCTGGCTGCCCAGTCTGGAAAGTG AGGAGCGTCTCTGCCCGGCCGCCATCCTGTCTAGGAAGTGAGGAGCGTCTCTGCCTGGCCGCCCATCGTC TGGGATGAAGTGAGGAGCGTCTCTGCCCAGCCGCCCATCATCTGAGATGTGGGGAGCACCACTGCCCCAC CACCCTGTCTGGGAGGTGAGGAGCGCCTCTGCCCGGCCGCCCTGTCTGAGAAGTGAGGAGACCCTCCGCC CGGCAGCCGCCCCATCTGAGAAGTGAGGAGCCCCTCCATCTGAGAAGTGAGGAGCCCCTCCGCCCGGCAG CCGCCCCTTCTGAGAAGTGAGGAGCCCCTCCGCCCGGCAGCCGCCCCGTCTGGGAAGTGAGGAGCGTCTC CGCCCGGCAGCCACCCTGTCCGGGAGGGAGGTGGGGGGCGGTCAGCCCCCCGCCCGGCCAGCCGCCCCGT CCGGGAGGGGAGGGGTTCAGCCCCCCGCCCGGCCAGCCGCCCCGTCCGAGAGGGAGGTGGGGGGGTCAGC CCCCCGCCCGGCCAGCTGCCCCGTCCGGGAGGTGAGGGGTGCCTCTGCCTGGCCACCCCTACTGGGAAGT GAGGAGCCCCTCTGCCTGGCCACCACCCCATCTGGGAGGTGTAGCCAACAGCTCATTGAGAACGGGCCAT GATGACAATGGTGGTTTTGTGGAATAGAAAAGGGGGAAAGGTGGGGAAAAGATTGAGAAATCGGATGGTT GCTGTGTCTGTGTAGAAAGAGGTAGACATGGGAGACTTTTCATTTTGTTCTGTACTAAGAAAAATTCTTC TGCCTTGGGATCCTGTTGATCTATGACCTTACCCCCAACCCTGTGCTCTCTGAAACATGTGCTGTGTCCA CTCAGGGTTAAATGGATTAAGGGCAGTGCAAGATGTGCTTTGTTAAACAGATGCTTGAAGGCAGCAGGCT CCTTAAGAGTCATCACCACTCCCTAATCTCAAGTACCCAGGGACACAAACACTGCGGATGGCCGCAGGGT CCTCTGCCTAGGAAAACCAGAGACCTTTGTTGACTTGTTTATCTGCTGACCTTCCCTCCACTATTGTCCT ATGACCCTGCCAAATCCCCCTCTGCGAGAAACACCCAAGAATGATCAATTAAAAAAAAAGAAAAAAAAAA GAAGAGAAGAATCAATTAGACGCAATAAAAAGTGATAAAGGGGACATCACCACGGATTCCACAGAAATAC AAACTACCATCAGAGAATACTATAAACAACTCTAAGCAAATTAACTAGAAAATCTAGAAAAAATGGATAA ATTCCTCGACACATACACCCTCCCAAGACTAAACCAGGAAGAAGTTGAATCCCTGAATAGACCAATAACA GGCTCTGAAATTGAGGCAATAATTAACAGCCTACCAACCCAGAAAAGTTCAGGACCAGATGGATTCACAG CCGAATTCTACCAGAGGTACAAGGAGGAGCTGGTACCATTCCTTCTGAAACTATTCCAATCAATAGAAAA AGAGGGAATCCTCCCTAACTCATTTTATGAGGCCAGCATCATCCTGATACCAAAGCCTGGCAGATACACA CACAAAAAAAACAATTTTAGACCAATATCCCTGATGAACATCGATGCAAAAATCCTCAATAAAATACTGG CAAACCGAATCCAGCAGCACATCAAAAAGCTTATCCACCAGGATCAAGTGGGCATCATCCCTGGGATGCA AAGCTGGTTCAACATACACAAATCAATAAATGTAATCCAGCATATAAACAGAACCAAAGACAAAAACCAC ATGATTATCTCAATAGATGCAGAAAAGGCCTTTGACAAAATTCAACAACCATTCATGCTAAAAACTCTCA ATAAATTAGGTATTGATGGGACGTATCTCAAAATAATAAGAGCTATTTATGACAAACCCACAACCAATAT CATACTGAATGGGCAAAAACTGGAAGCATTCCCTTTGAAAACTGGCACAAGACAGGGATGCCCTCTCTCA CCACTCCTATTCAACATAGTGTTGGAAGTTCTGGCCAGGGCAATCAGGCAGGAGAAAGAAATAAAGGGTA TTTAATTAGGAAAAGAGGAAGTCAAATTGTCCCTGTTTCCAGATGACATGATTGTATATTTAGAAAACCC CATTGTCTCAGCCCAAAATCTCCTTAAAGCTGATAGGCAACTTCAGCAAAGTCTCAGGATACAAAATCAA TGTGCAAGAATCACAAGCATTCTTATACACCAATAACAGACAAACAGAGAGCCAAATCAGGAGTGAACTC CCATTCACAATTGCTACAAAGAGAATAAAATACCTAAGAATCCAACTTACAAGGGATGTGAAGGACCTCT TCAAGGAGAACTACAAATCACTGCTCAACGAAATAAAGGAAGACACAAACAAATGGAAGAACATCCCATG CTCATGGATAGGAAGAATGAATATCATAAAAATGGCCATACTCCCAAGGTAATTTATAGATTCAATGTCA TCCCCATCAAACTACCAATGACTTTCTTCTCAGAATTGGAAAAATCTACGTTAAAGTTCATATGGAACCA AAAAAGAGCCCGCATTGCCAAGACAATCCTAAGCCAAAAGAACAAAGCTGGAGGCATCATGCTACCTGAC TTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGGTACTGGTACCAAAACAGAGATATAGACC AATGGAACAGAACAGAGCCCTCAGAAATGACACCACACATCTACAACCATCTGATCTTTGACAAACCTGA CAAAAACAAGCAATGGGGAAAGGATTCCCTATTTAATAAATGGTGCTGGGAAAACTGGCTAGCCATAGGT AGACAGCTGAAGCTGGATCCCTTCCTTACACCTTATACAAAAATTAATTCAAGGTGGATTAAAGACTTAA ATGTTAGACCTAAAACCATCAAAACCCTAGAGGAAAACCTAGGCAATACCATTCAGGACATAAGCATGGG CAAGGACTTCATGTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATGGACAAATGGGATCTAATT AAACTAAAGAGCTTCTGCACAGCAAAAGAAACTACCATCAGAGTGAACAGGCAACCTACAGAATGGGAAA AAAATTTTGCAATCTACTCATCTGACAAAGGGCTAATATCCAGAATCTACAAACAACTCAAACAAATTTA CAAGAAAAAAACAAACAACCCCATCAAAAAGTGGGCGAAGGATATGAACAGACACTTCTCAAAAGAAGAC GTTTATGCAGCCAACAGACACATGAAAAAATGCTCATCATCACTGGCCATCAGAGAAATGCAAATCAAAA CCATAATGATATACCATCTCACACCAGTTACAATGGCAATCATTAAAAAGTCAGGAAACAACAGGTGCTG GAGAGGGTGTGGAGAAATGGGAACACTTTTATACTGTTGGTGGGACTGTAAACTAGTTCAACCTTTGTGG AAGACACTGTGGCAATTCCTCAGGGATCTAGAACTAGAAATACCATTTGACCCAGCCATCCCATTACTGG GTATATACCCAAAGGATTATAAATCATGCTGCTATAAAGACACATGCACACGTATGTTTATTGCAGCACT ATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCATCAATGATAGACTGAATTAAGAAAATGTGG CACATATACACCATGGAATACTATGCAGCCATAAAAAAGGATGAATTCATGTCCTTTGTAGGGACATGGA TGAAGCTGGAAATCACCCTTCTCAGCAAACTATCGCAAGGACAAAAAAACAAACACTACATGTTCTCACT CATAGGTGGGAATTGAACAATGAGAACACTTGGACACAGGAAGGGGAACATCACACACCAAGGTCTGTCA TGGGGTGGGGGTAAGGGGGAGGGATAGCATTAGGAGATATAACTAATGTAAATGACGAGTTAATGGGTGC AGCACACCAACATGACACATGTATACATATGTAACAAACCTGCACGTTGTGCACATGTATCCTAGAACTT AAAGTAGAATTAAAAAAAAAAAAAGAAAATTCACTAATTAGGTGTGTGACCTTGGGTAAAGTTCAAGAGC AAAGCTACACAACTTCCCTAAGCCTCAGTTTCTTCATCATTAATTGGGGAAGTGCTCTGAGGCTCAAATG AGGTCATGCACATAAAGCACTCGGCATGGGCAGGGCATCTGAGGGAAGCCTGAACACTTGGCATTGGGCA TTGTTATTGTTCTTCCTCAGGCTCCTCTCATGTTGTTCTTTCTTTACAGCAAAGTTGGCCCGAGATGACC AAATTCACATTCTCAAGCAACACCGACGTAAAGAACTGGAAACACGGCAAAAACAATATCGGTGAGTTAT GACATCAGATCGAGTGGCCACGGGGCCATGGTTTCTTCTATCTCAAGAGCATGGTATGAAATAAACCCTT TCCACAGTGTATGGCCTGTCACTGCTGGAAAGTCACCAAGGCACCAGCTCCCAGTGTGGGTGCACAATCC CCAAACTTCACCTTACCTACAACTCCAGACAAGAGATGGAGAGGAGAGTAATGAAAATAACTTTGGATCA ACCATATTGGCATGTAGGAAGAATGGGCAGAAAAGCTTGAGTGTACCTTAATGTTCTCCATTGTAGGGGT TGCCTCTTACTTCTTATGTCTTCTTATAACAATTCAATTATAAAAGTGATACATGATCAGCAATAAAATT GACAACTCTTCAGCCAACTGACCAGAGGATTCAAACCATTAAAATGAGCAATAAGAGAAAATCAATACAG AAATTAAAATGAATAAAAAAGGAAAAATGAGACTCATAAAATGAGGGAAAATCAATACAGAAATTAAAAT TAATAAAAAAGAATACTATGAACAATTGCATGCCAACAAACTAGTTAAATGAAATGCGCAAATTCCTAGA AAGACGCAAACTGCCAAAACTGACTCATGAAGAAATAGTTAATCTGAATAAAACAATCACAACCAAAGAG ATTGAATTACTAATTCTAAAATTTCCCACAAATAGAAGCCCAGACCCAGATAGCTTCACTGGCTAATTCT ATCAAACATTTAAAGAATTAATACTGATCTTGCATAAACTCTTTTAAGAAATAGAAGGAACACTTCCCAA TTCATTGTCTCATACCCATATTATACCAAAACTAAAGGCATCACAAGAAAACTATAAACCAATATCCCTT AGCAATATAGATATAAACATTTTCAACGAAATACTAGCAAACCTAACCCAGAAGTATATAAAAGGCATTA AACAATATGAACATGTGGGATTTAGCCCAGGAATGCAAAGTTGGTTTAACATCCAAAAATCAATTAATTG AATTCACCATATCAATAGAGTAAATAACAAAACAAAACAAAGTACATAATCATTTCAATAGACATACAAA AAAGGCATTTGACAAAATCCAACACCCATTCATGATAAAACACTCAAAAAATAGGAATTGAAGAAAATGT CCTCAACCTGATAAAGGTTTGAAAATTCACAATTAGGCTGGGCGTGGTGGTTCACACCTGTAATCCCAGC ACTTTGGGAGGCCAAGGCGGGTGGATCACGATGTCAAGAGATTGAGACCATCCTGGCCAACATGGTGAAA CCCCGTCTATACTAAAATACAAAAAGTAGCTGTGTGTGGTGGCATGCGCCTGTAGTCCCAGCTACTCAGG AGGCTGAGGCAGGAGAATCACTTGAACCCAGAAGGCGGAGGTTGCAGTGAGCTGAGATCATGCCACTGCA CTCCAGCATGGTGACAAGCAAGACTCCGTCCCCCCACATACACAAAAAAAGAAAATTCACAGTTAACATT ATACTTAATGATGAAAGGCTGAATCCAGAAACAGGATAAAGATGTTCACTTTTGCTACTTCTATTCAACA TTGTACTGGAGGGTCTAGCCAGCTCAGTTAGGGAATAAAAAGATAAGTAAAGGCACCCACAATGGAGTAC AGTAAGTAAAACTACCACAATTTACAAATAACATGATCTTATATATAGAAAATCTGAAGGCATTCACCAA AAGAAATTATTAGAACTAATAAACCACCAAGATTGCAAGATACAAGATAATCAATTGTTTTTCTATACAT TAACAACCAACTATGTGAAATAAAAGTAAGAAAAAGTTCAATTTACAATAGCATCAAAAACAGTAAACAT TTATGAATAAATTTAACAAAGTAGTCTGAGACTTGTACAATGAAACTACAAAACATTGTTTAACATTATT AAAGAAGATCTAAATAGGTTGAAAGACATTTCATGTTCATGAATCAGAGGACTTAATTTTGTTAAAATGG CAATACCCCACAAATTAATGTACACGTTCAACACAACCCTTATCAAAATTCTAGCTGATTTCTTTGCAGA AATTGACAAGCTGTCAATTCTGCAAATTCATATGGAAATGGAAGGGACCCAGAATAGCCAAAACAATCTT GATAAAAAGAAAACAAAGATGGAGGACTTGCACTTCTCAATATCAAAATTACTACACAGCTATAGTATTC AAGACAATGTGATATCGGCATAAGGATAGATATATAGATCAATGAAATAGACTTGAGAGTCCAGAAATAA GCCCTTACACTTATGGCCAATTAATTTTTGACAGAAGCAGCAAGACAGTTTAACAGAGAAAGAATAGTCT TTTCAACAAATGGTCCTAGCAAAACTGGATAGCCACATGCAAAAGAATGAAGTTGGATCCTTAGCTCACA CCATATACATAAATTAACACAAAATGAGTCAAATACCTACCTAAATGTAAGAGCTAAAACTATAAAACTC TTTTAAGAAAACACAGGAGTAAACCTTCATGACTTTGGATTTGACAAAGGACTCTTGATATGACACCAAA AGCATCAGCAACAAAAGAAAAATAGATAAAGTGATAAAGTGATGTCATCAAATTTACAAACCTTTATGTT TCAAAGGACACCATCAAGAAAGTGAAAAGATGAACCACAGAATGGAAGAAATATTTACAAATTGTATATC TGATAAGGGCCTTCCATCCATAATTTATAAAGAACTCTTACAACTCAATAAAGACAAATAGTCCAATTAA AAAATGAAAAAAATGAGTGAGGATCTGAATAGATATTTCTCCAAGGACCCATTAGTCATCTAGGAAATGC AAATCAACACCACAATGAGATACCACTTGATACTAGGATGGCTAGAATAAAAAAATCCGACAAGAACAAG TGTTGACAAGGATGTGGAGAAATCAGAACCCTCATACACTGCTGGTGGGAATGTAAAATGGCACAGCTGC TTGGGAAACAGTCTGCTAGCTCCTGACTGTTCAACAGAGAGTTACAATATGACAGCATTTCCACTCTTAA GCATATTCCCAACAGAAATGGAAACATATGCCCACACAAAAACTTGTACATGCATGATTATAGCAGCATG ACCTGTAACTATCAAAAAGTGTACACAACCCAAACGTCCATTAATGGATGAATGGATAAAATATAGTATA TCTATATAATTTGACCATGAAAGAAGAATGAAATACTGACACTTGTTACAACATGGATGAATCTCAAAAA CATTATGCTAAGTGAAAGAAACCAGTCACAAAAGATCATATATTGTATGATTCCTTTTATATGAAATTTC TGGAAAAGAAAAATCTGTACAGATATAAAGTAGATTACTGGTTGCCTAGGGGCAGGGAATGAGGAAGTGG TCATGGGAGTGACAGCTAAAGGATACAGTGTTCCTTTTGCCGGGGATGAAAATGTTCTAAAACTGATGGT TGTCCATTGTGTAAAAATTAATACTAAACATCCTTGAATTGAACACTTTAAATGGATAAATTTTACAGTA TGTGCATTATATTTCAATAACGCTGCTAGATAAATTTAAAAATTAATTCAAAATGGATGATAGATCTAAA AGTAAGGGCTAACAACATAACACTCTTGGAAGAAAACATACAAGTAAGTCTTCATAATCTTGGGTTCGGC AAAGTCTCTTAGATATGGCACCAAGAGCACAGGCAGCAAAAGAAAGTAGACAAGTTAGATGTCATTAAAA TGTAAAAGATCTATGCTTCAAAGGACATCATCAATAAAGTGAAAAGACAATCCACAGAATGGAGAAAATA TCTAAATCATATGTCTGATAAGGGACTTGTATCCAGAATATATAAAGAACTCTGACAACTCAATTTTAAA ATATTCTGTACAAAAAACCCCGTTTAAAAATTAGCAAAGGATTTAATTAAATAGTTCTCCAGAGAAAATT TGTGAATCTCCAATAAGCACGTGAAAATATGCTCAACATTATTAATCATCAGGAAATTTCAAATCAAAAC CACAAGATACAATTCTAACCACTAAAATGGTTAGAATAAAAAAGACAGATAGTAACAAGTGCTGCCAAGG ATGTGGAGAAACTGGAACCCTGATGCTGCTACCGGAATGTAAGATGATGCAGCCACTTCAGAAAACAGTT TAGTGGTTCCTCAAAATCTGAAACCCAGCTACAATATGACCCAGCAATTCTACTCCTAGGCCTCTACCCA AGAATATTGAAACCACATGTCTATACAAAACTTGTACACACATATTTATAGCACCATTGTTCACAATAGT CAAAAAGTAGAAACAACCTAAATTCCATTAACTGAGGAATGAATAAACAAAATATAGTTTATCCATACAA TGGGATATTTTTTGGCATCAAAAAGGAATGAATGCCAAGCGCGGAGGCTCACACCTGTAATCCTAGCACT TTGGGAGGTTGAGACGGGCAGATCACTTGAGGTCAGGAGTTTGAGACCAACCTGGCCAACATGGTGAAAC CCCATGTCTACAAAAATACAAAAATTAGCCGGGCATGTTGGTGCACGCCTGTAATCCCAGCTGCTTGGGA GGCTAAGGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCTAGATCCCGCCACTGCAC TCCAGCCTGGGTGACAGAGCAAGACTCCATTTCAAAAAAAGAAAAGAAAAGAAAAGAAATGAACTACAGA TAGATGCCAAACACTGAATGAACTTCAAAAATATGCTAAATGGAAAACTCACTTACGGAAGACCCCATAT TGTGTGATTCTATCTGTATGAAATGTCCAGAATAGGCAAACCCACAGAGTCAGGTTAGTAGGTGAGTAGT TGCCTAGCACTAGGAGTTGGGGAGGGGAAACAAGGAGTGAATGTTAATGGGTTCGAGGTGTCCTCTGGGG ATGAGATTATTTCAGAATTGGGTTATAATGATGGTTACACATACAACTCTGCAAATATATTAAAATCTTT TGATAGCATATTTTTAAGGGGTGAATTTAATGGTATGTAAATGTATCTCAGTAAAGCTTTTTGGAAGATA ATAACACATTACAGAGTGCTCCTCTGGAAATGGGTGGCTGATGGGCTGTATCCAGCCTCTACAAGTGTTT GATGGATCATTATTGACTTATGAGTAAACAGAGATATTCTTCAGGCTTCCCCAGTCCACACTTGTCTGTT GTCTATATCAAGGTTTTCTTTCATTTCATTTCCTGCTTTGGCCCCTGGAAACATTTGAGTCTGTGCCTCC TTCCAAGGGAAGAAAGTGGAAGGAATCATTCTACATGGACAGTGAAGTTACCTGGGCTGTGGAGGGGCCT TTGGGAGCCAATATTGTGATACTTTTCTACATATCCCTCAATAGTTGAACTTCTTACAAGGAATATGTAG TATATCTGGGTTGTTTTTTTAACTCAAAAAAGTAAAAGAAGGAAAATAATATAGAGCCAGAAAAATACCT ATTTTCTGTATGAATTATGAATTTTATGAACTTTTTCATAAAAATTCATGTTTAATTGTTTTCACTTTGT CTTATTCACTTTTTAAAATTTGGGATTGTGCTATATATACCACTTTGCATCCTCCTTGCTGCCCTTTAGC AGTGTAGCAAAAATCATTTTCCCATATTTTCAAAATCTCATCATAAACATTATTCTAGTTTCTATGTACT ATTCCATTGGATGGATGCCTCATCATTCACTTAAACACCCAGCTTCCCTGGACATTTAGGAGGTTTCTAA TTTTTGTATTCTTATAAGCAAAGTGAAAACCCTTGTATGTGAAATTTGTATACATTATTAAGTATTTTCC TAGGACAGATGCCCAGATATGAAATTACCAAATAGTAAAAGTTATTAGTATACATTGACAAATTTCTCCT CAAAAATCTTTAACCATTTGGGAGGCTGAGGTGGGTGGATCACCAGGTCAGGAGATCGAGACCATCCTGG CTAACACGGTGAAACCCCGTCTCTACTAAAAAATACAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGT AGTCCCAGCTGCTCGGGAGGCTGAGGCAAGAGAATGGCGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCC GAGATTGCACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAA ATCTTTAACCAGTTTTCACGAGCCATGTATGGGTCCCTGTTTCATCAAACACTTGCCATAACTGAGCAAT ATCTTCATTTTTCTTAATTTTTCTAAGTTGCAACAGCATCCCTCAACCCTGTAGCTCCTTCTTCCCCTAT GCCCAGCCACCCACTGCTGTCAAGGGGTGAGAAATCCCACACCAAGAACACAATTGCCCCACCTCAAAAC TGTCTTAGCTTCATCCCCCTTTTCATCAAAAACATTCCTTGAAACAGAATAAAGAAACAACAAACAGCCA CACGTATGTGGGTACTGGGTCTGCTACGGAGGGCTCGGCTGATGGGTGGCACTGGGCCACTGGACATGCA TCTCGAGGACAGGGGCCAGCCAGCACGGAGGGCTGAAGGAGAAGGAGAAGAAATCAGACTCCACCTCTTG CCATTCAGGAGACTCAGCTTGGGGTTGATTAGACTTAAAAGTTAAAGGCAAAACTGTAAGACATTTAGAC TACAGGTGATTATTCTTCCAGGTCTCAAGCTAAAAGGATTTTTCAAACAAGACTCAGAACATATTAAACA CAAAGGAAAAGATTGGTAAGTTTGCCTCCCTCAAGATAAGGACACTCTGTTCATTGAAAGACACCAGGAG AGAGTGAAGGCAAGTCATGGAGTGATTGACGAGAATTATTCCTAGTATGTGAAGGACCTACAAATCTTTA AGAAGGGGAGTGTCATTCACTAGAAAATGGGCAAGAAGTTTGAGTACTTACTGTACAAAATATAAGCAGC AAGTATACAAAAGGTGTTCAACTTCATTAGGACTCGGGGAAATCAGAAGATCACAGTGAACTGCTGCTAC TACCACACATATGCCCCCAGATGGGCAACACTTCAACAACTGACAACACCTGAGTATTAAAGAAGATCCA GAGGGCTGGGAACACTCATATACCACCGGCAGGAGGACAAGTTGGTAAGACCTCCGTGGAAAACAATTTA GCAATATGTCATAAAACTGAAGCTACATTATAATCTATGACCCAGAAATCCTATAGTGGGATCCAAATTT GTGTGCATGTGCGCCTGGATACTCACAACAGCATTACTCATGATGGCCAAAAAATGGCAACAACTCAATG TCCAACAAACAGTAGAACAGACAAATTGTCAAGGAAAATTCTACACTGCAAGGAAAATCAACAAACTGCT GCTAACATGGACAAACCTCACTGACGCAGTGTTGAAGGAAAGAAGCCAGGAGCGTGTCTGGCCAATTCAT AACTTTGGAATGAAATTGTTTAGGGAGGTGTGTCATAGCGGAACCTTAAACAATAACAAGAAAATGATTA TCATAAAGCCGAGGATGGTCATTACCGGGGATGGAAGGAGGGTTGATTGGGAAAGGTGGGGGTGAGGGTA CGGACAATGTTCTGATTTTTTACCTGGATGGTGTTCGTACAGGTGTTTTGTACATTTTTCTGCATGTGTG AGTGTGTGTGTGCATATATACATATCCATACATATTTTATATATTCTATTTCCCAATTGAAAAATCAAAA ATAAAACTTACATGCCATTAGCATCAAGTGTGGGAGAGTAACCTGCTGTGCTGTGGGTCATGTTAAGGGT TTATAAATGTGTGATTTGTTTTAGAGTATTTGTGCACAAGCCTCTCAGCTCAGGCACCATATGATGTGTT TCCAGACTTCCATACCTGGTGCAGTGCACACGTTGTGCTTGAGCTCTGCCTCCCATCCCAAAGGGCTGTT GTTTCTATGCTTCTTCCTTGGCTTCCCTCCCTGTTTCAGACACCTATGGCAAAGCCCCTGCAGCCAGTTC TCAGAGCACTTCTGGCCTGTGAATCTGGGTTAAGATAAAATGCCCATAAAATTCATTTAATTTGTTATAA GCCACTAACACTTTAGTATGAATTAGTGGGGCTCTAATTAGACTTTGCTATCTACTCATCTAAGATAACA CAAACTAGCCCAATTATCTGGGAGCTACTTAACATTATCATAATCTTGCAGCAGGGGGCTTCTGGTGAGA TCGTTTCCCCCTTTCTTAGATTTAATCATTTTTTTCTTCCTCCTTCCACTCATCTGTCCTTTTCAGAAAC CCTCCTTTGCTTCCGTTCAGGAAACACTGAACTTTGCACTGTCTGCACAATCTTGGAGTTCCTCTTTCTC AGAAGATTTCTCAGGCTTCCAGATCAGAGTTTGGAAGTAAAGCAATGACTAAGAATAGTCCACACTATGT CAGAAAGCTGGCGCTTCTTGCAGGCCCTCCTTACTCACTCAGCCACGCAGGGAGAAGGAGAAGCAGACCC AGGTCATAGCCCACAGCTTGTGCTCTCCCACTGTGACCACATCTGTCTGTGTTACATGCACACTCACACA CAGCAGTAAATGGCAAAGTGTAGGTGTTTGTTAATCGATATAATTTAATCTAATCATTATGTGACCTGCA CTTTTCACTCATCACTAAGTATTGAAGAGGATCTGGTTGACACAGATAGATGTGGTTCATGCAGTTAACT TCTTCATGGCATATCAGTATCTGAATAACCCATGCGCTCGTCCGCTCTCCTGCTGATGGGCAGGCGGGCT GTCTTTAATTTCTAGCTGTTGCAAACCAAGCGACAGTGAGCTTTCTCACACATCTCTCTGTGCTCTCATG GAAGAGTTACTGTAGGGAATATTCCAAGAAGTAGAGTTGCAGGGTTGCAGACCACGTGTTTTTAAGCTTT CTAGATATTGCTGATTGTTTTCCAAAGGCATTCTGCCAGTAGACACCCCAGTAACTGTTTCTGAGATTCA CTGTTTCCCTGCATCATCAACACTTCGCATCTTCAGATGTTTTCATTCTTGCGTGTGAAATAGTATCTCA TATATTTTCCCCTTCTTAAACTGCTACTATTTCTTGCCTTCTGGGAATGCACCATAATTTACTTAGCCAT TCCCCTATTCACTGACGTTCAGTTCATTTCCCATTTGTAGATGTGTTTGTTTGTTTTGGGTATTGCAGTA CAAACAATGCTGCCAGAACCAACCTTGTACAAACATCTTGATGTACTGGTGCTTTAATTAATGGCAGATC CATTTCCAGAACTCAGATTGCTGGAACAAATCAGCATTTTTTCATCTTAAGAAATACCGACAAAAATCCT TTCACAAAATTGTATCGTAATTTGCGGTCCTACCAGCTGTGTATGAAAAGATACTTTTGCCCATCCATAC ATTTGTCAGTACCCGATGACCTTGTTTGACAGTCTAAAAATCCCTAAGACCTTGTGGTTGTTTTAGTCTG CACTCCCCTGACCACTAATAAGCATCACTGCATTGCCTATTTATAAGCTTTTTTTCCCTATTGTTCTTTC AATTATTAATCTAAAGGAGCTCTTTCTATATCAGGATAGTATCCGTTTGTTACATATGTATAGCATTTAT TATTTGTCTTCTGTTGCTTTTGCCACAGGAGATTTTAGTTCTTTATTTTATTAACTATGTATTGTTTACA TCTATAACTTTTGGGTTTCCTCCTTTGCTTAAGAAAACCCTTTCCATCCCAGTGTTACACAAATACTTCC CCCGTAATTTTGTCTAATACTTTTATAATTTCCCCTTTGAGTTTAGAGCTTTCATTCATCTACCTTTTTT TTTTTTTTTGAGACAGAGTCTTGCTCTGTTTCCTAGGCTGGAGTGCAGTGGCATGATCATGGTTCACTGC TGCCTCAAACTAACCCAGGCTCAATCCATCTTCCCACGTCAGCCTCCCAAGTAGCTGGGGCTACAGGCGT GCGCCACCATGCCCCACTCCTGCCACGTGTTTTCATACATACCTGGGTGGAACTCTCCCGGTAGCATTCG TTCCTGACTTGGATGACAGGGATGATGTCTTTCCTCCTGACTTGGATGACAGGGATGATGATACCCACGG TACAAGCTGGCATAGGATGGCAGTCATGAGCTCTGGATTCGAGTGTCTGGGCTCAACTCACACTTACTGG CACTTTCTCCAGTCCTGTGAAAGTTGTTTAATCTGTCTGTGCCTCACTTCCCTCATCTGTAAAATGAGGG AAATAACAGTGCCTTCCTTTTAGGGGTTTGAGATAATAGGTTAAACCATGAAAACACAGAGAATAGTAGT AGGCACATAGAAAGCACTGGATAAGTGTTGGCGAGTTTTGTATTATGTATACATAGTCTCTGGGTCTGTT TCCGCACTTTATGTGTTAGCCTATTTTTCTACTCGAGACCCCAGCACCAGCTTTTGGTTATCATAACTTT CTAATAAATGTTAATGTCTGTTACATATCTCACTGTTCTTTCTTAAGTTTTTCATAATGAGAATTACTTT GAACTTCACATAACTGTGTTATGTGTTGGCATTTTACTGAGATTCAGTCTTTCCATCCAGGAACACAGCG TGTCTTTCCACCTCTCTAGATCCTGTGTCAACGTACTTCCATAGAATTTCTAGTTTTCTTCATGCAGGTC CTTCACCTTTCTAGCTACTCTACATTTAGCATTTGCTGTTCTGAGTAGGATATTTTTCTGTTTGCAAAAA TATTGCTGGGATAAATGTAAATTACTTGTTTCTTACATTTACTGTGTGTTGGTCCCTTACTGAATTCTTT CATTGGTTCTAATCACTTGTTTTTGTTTGTTTGTTGTTAGTGAGTCTGGTTAGTTAATGTGCTCATATTA TCTAAATGTTAATAATTTTGTCTCTTACTTTCCATTATCTACACCACTGATATTCTTTTCTTATTCCATG TCTGGAATTCCCAAAACAAGTAGTGGTAGTAGTGATGAACATCCCTCTCATATTTTTGTTTCTTTGTTTA CTATTATATTTGCTGTAGTTTTATAATGCATATTCTTTGCTGTATTTAGGAGTTTATTGATTCATTCTAA TTTAATTTTTGTTCAGCTGAACTTGTTCAATTAATTTCCTCAGAAGGTCCATGTGTAGTGTAAGATCTGA GTCTGTGCTTGTCGTCCTGTCCCCCTACCCATCCCCTCAAACAAATTCCCCTGCCCTCATTGATGACAAT ATGAGAGGCTTAGATGACGATCTAAAAAAAGTGTGTATACACTTCAGTCTTCCCATTTTCAGAATGACAG AGGAGAAATCTAATGATAGTTTGTTTCTTTTCCTAGAGTTTCTATCTCCCTCCCTCCCCCACTTTCTTCC TCTCTCGTTCACTCTCTGCATCTCTTTCCTTCTCTCTGTCTCTGTTTCTCCTGTCTCTTGGACATTTTAA AATGTATTCAGTATATACCTAGGTGTATCTTTTTCCTTTTTTTTTTTCCCCCCCACCTAGGACTTGTCAT TGAGAAAAATGACGAGACAAGTCTCAATCATTTTAGGAAATTTATTTGCGAAAGTTAAGGACGCATGCCC GGGAGACAGCACTATGCCTTTCTCTGAAGGTGATTTTGAGGGCTCCAAATTTAAAGGGAAAAGGGCGGGA TATTGAGAAGTACACAATTTTCATGTAAGAGCAGGGCAGGGAAAAATAGTTATTCATGCCTTTCTCTGGC TCAGTGAATCTGCATTTTTTTTAACATAAGATGACATAAACAAATGAGGCAGAGGAAAAATGCAGGGAGT CTGCATTTTACATAAGAGAACATAGATAAAGTAAGGCAGGGGAACAATCAGATATGCATTTGTATCTGGT GGGTGACTGCACTTGTAAAGATAAGCTATCAATTTGCATTGCCATGGTGAAATTTTAACGGTTCACTAGG AATTTCCTTGTGAGCAAAATATGGTGGAGACATGTAGCTTTTCATCATAGCCATCTTATTTAGGAACCAA AAGGGGGAGGCAGGTTTGCATGACACAGTTCCCAGCTTGACATTTCCCTTTGGCTAAATGAGTTTGGGGT CCTAAAATTTAATTTCCTTTCACAGACTTAAGATATTGAAGTATTTTTCAGCTTAAAGGAGTTCTTCTTT TATTTCTTTGATTTTTTTCACTTCTCCATATATTACTCTCTCTCCTTTTGGAGCTTTTACTCCTTGCATA TTACATCTGTATCTGGCTTTCATGTCTGTTAATGAAAAGAGTCACACTCTGTGAAATATTTGAAAAGACT TATTCTGAGCCAAATATGAGTGACCAGTGGCCCATGATGCAGCCCCAGGAGATCCTGAGAACATGCACCC AAGGTGGTTGGGGTACAGCTTGCTTTTGTGCATTTTAGGGAGACATAAGACATCAGTCAATACATGTAAG ATGGACAGTGGTTTGGTTTTGGAAAGGTGGGACAACTTGGGGGAGGGGAGCTTCCAGGTCATAGGCAGAT TCAAAGAGTTTCTGATTGGCAACTGCTTAAAAGAATTATTATCTAAAAACTTGGAATGTCTAGGTTAAGA TAAGGGGTTGTGGAAACAAAGTTTTTTATCATGCAGATGAAGCCTCCAGGTAGCAGGCTTCAGGTAGAAT CAATTGTAAATGTTTCTTATCAATCTTAAAGAGTCTGTTCTAATGGGCTTAACATCTCTGTGTTGATGTG AATGCTGATCAGTTGTGCCTGAATTCCAAGAGGAGGAGAGTACAATGAGGCACGTTTAGCCACCCATTCC TATCATGGCCTGAACTAATTTTTCAGGTTAACTTTGGAATGCCCTTGGCCAAGGGGAGGGTCCATCAGTC AGTTCAGGGGCTTAGAATTTTATTTTTGGTTTATGTCTCTCATAGTTTCATTTATGGCTTCCATTTCTTT GTAGTTTCACCCTGTATTTGGGTTACATGTTCTTCTATTTTGCACAAAGCACTTCCTGGCACATAGTAGG TGCTCCATAATTAGTTGTCGAATGAACACCTTCTCTCTTCTAGGTGTTAATGAGTTTAGCTTAAACTTTT CTCCTTACATATTTTAAATTCAGCCTAAAAGTTTCTCTGTACATAGTGAACTGTAACCTAACTGGATGTG TAAACAGACTGTCACCTACTCTCATAGCAAGTAACCAAGTCTCAGCCAATCACAGCGGCCAGACTTCAGC CACTCACAGTGGCCAGCTGTTCAAACTGGGCTCAAGTAAGGCAAATGCTGAGCCATCACCAATCTGGCTG TTTCTGTACCTCACTTCCATTTTCTGTACATCACGTTCCTTTTTCTGCCCATAAATCCTATCCAACTATG AGACAGCATCAAAGTCACTCGGAGCCTGCTCTGGTTTAGGGGCTGCCCTATTCTTGAATTGTTCTTTGCT CAATTAAACTGCTAAATTTAATTTGTCTAAAGCTTTTCTTTTAATACAAGAGACCAAACATCTCACAGTG ATTATTCTCTTTGTCTGTTTCTCTATTGAAGTCTTCATTCAGAAATCATGTTTGTGGTTACAGAAAGTCT TTTTACACTCCAATTATACTAACTGCATCCCCTTAGGATCTCTCTGTCTGTCTGTCTCTCTCTCTCTCTC TCTCTCTCTGTCTCTCTGTCTCTCTTGCTTTCTCTCTCTCTCTTTCTCTCTCTCTCTCTCTCTGTCTCTC TGTCTCTCTTGCTTTCTCTCTCTCTCTTTCTCTCTCTCTCTCATTTTTTTTCCAATAAATTAAATGCCTT TCTACTTCTTTGTTCCTTCTGCCTGGGTGTTCCACTTGGTCTTCCTCAATGGAGTGGGATTCCATCTCCA CCAGTTAATGTCTGTGGCCATGCAGGCCTTCGGCTCCTGTGCAGGTCAGCCTGTCAGGGTCTCTTAAGCA GCAGTGACCTGCAGTGGAAGGGACATAAACATTTGGTTTCAGGGGGGCAGTAGTGAACTAGCAAGCAAGC TGTCCTGTCTCCATGTGCTGTGAGGCCATCATCTTCTAACCACACAAGTGGGGCATTTCTGCCCATTGGT GCTGCCACCCTCCATAGACCAGGGCAGGGCATGGGGCAAGAAGGTCTTTTTGGTGCTGAAGAAGTATTCC ACATCCGTCCAAGTGGACTATTCACTTAAGAAAACATTAATGCCATTTGCTGGCACAGATGCCCTTGCAT GGCTCATTGTTTACATACTGAAAAACATCTAGCTCCACTGAGCTTTTAAAATTAACTAGAGCCCTTGAAC TGTCCAGGCAAAGAGAAAATCATCAGTAATATTTAAATTGATATGACTAATGATAGCTAATTAATTGATC ATTACTACCAGTGAGGCTACTGAATGGCTCAATTTTAGATATATATTGGAGATGCCTTGAGTCATTTTCC AAAACAAACAAACAAAAAATGTGTAGACTTGTCCACATTTTTATCCTTGTTAATATACTATCATTGGCAT TAATACAAACAGCAAAAATGGAAGGTTTTCTTAAAATCTGAGGACGTAGAATATTCTAAATAAACCAACA GTGAGAAATGTAAGGTGCCACATAACAGAAAACACTTGACAAAATGCCTTTGCTGTCAGAAGGATCATAC CCGGTCCCTGTTCACTTCTTGTGATCCTAAGGAGAGGCTACTGGGCCAAGAGGACACTGTGACAGTTGGG ATTTGGGGAAAGTCAAAGCACAAGATCATATTAAAATAACTCAGGACTTTTTTAAGACCCAAAATCTCGA TATTTTACTTTCCTCTCAAAAGAAAATTTTAAAAGGAAGGAGAATTAGGAATATAAATGAAAAAGCTAAA ACCCTAAAATGTAAAATCTGGTTTTTAAACAAACACAAAATCATTCTCCCTCCCCAAAGAAACTAACAGG ATTTCATTTTGTTTTTGTTACCAGAAAGGGGTCCTGATCCAGACCCCAAGAGAGAGTTCTTGGACCTCCA CAGGAAAGAATTCAGGGTGAATCCATAAAGTGAAAGCAAGTTTATTAGGAAAGTAAAGCAATAAAGAAAG GCTACTCCATAGGCAAGGCAGTAGCATGGGCTACTCGACTGAGCATACTTACAGTCACTTCGTGATCATG TGCTAAACAATGAGTGGATTATTCATGAGTTTTCCAGGAGAGGGGTGGGCAATTCCAGGAACTGAAGGTT CCTCCCTTTTTTAGACCATATAGGGTAACTTCCTGACATTACTATGGCATTTGTAAACTGTCATGGCACT GGTGGGAGTTTCTTTTAGCATGCTAATGCATTATAATTAGCATATAATGAGTGGTGAGGATGAACAGAGG TCACTTTCATCACCATCTTAGTTTTGTTGGGTTTTGGCCGGCTTCTTTACCACAACCCATTTTATCAGCA AGGTCTTTCTGCCCTGTATCTTGCATCAATGTCCTGTCTCATCCTGTGACTTAGAATGCCTAACCTCCTG GGAATGCTGCCCAGTAGGTCTCAGCCTTATTTTACCCAGCCCCTATTCAAGATGGAGTTGCTGTGGTTCA AACACCTCTGACATTTTCACAATTTAAGTTTACTCAATAAGTAAACAAAAAAGCAAAATAAACATTTTTC AAAAACACAAATGCCCAATGCCACGGGATACGTTTCAAGGATGTCAGGATCTGAGCATGTTTACTGGATG CAGTCCGTGGCTTGTCTTTGGGGAAGCTGTTTTGATTGTAATAATCTCTAAAGCTGCTATTGGCCAGCAG GTGAGAGAGGGAAGCCTTTTAGCCATCTGTGCCTGGGTCCCTCTCCCAGGCCACCTGCTGCCGTGTCGTC CTATTGTGAAGGCAGAAGAACTGTCCCATTTCCCCAAATGCCACATGCAGGACATGCACGCAGTCCAGGG CACACACTGATCAAGTTGGCAGAATGGTGGATGTCCAGGTTGGGCGTGGCTGGGCAGCCTTAATACCTTC TACCTCCAGTGACTGGCAAGGCAGGCCTCTACTGTTCAATGTCACCTCTAGTAAGTGAGGTCTCCCTAGA CTACCTACAGAACTTTTTATGCAGTGGTGCACACCTGTACCACTATAAGCCCAGTCTCAGGGTTCCCACT CTGATGCTCAGGGCACAGCAAAGTTGGTGCGACTGGACTTTGGAAGAGGTCCCAGAACCTTACTGGACAC AGGGTCAGCCTATGATGTGTTGACTTTATTTTGAGTACATCAATCTCCCTGTGTAACATCGTCTGACAGT GTGGGCGGCCCTCAGCTGAGGGGGCAGACCAAAGGCTGGCATTTAACTCAATTTCTTCTCCTTTCTCATG CTCAGATGGATGGAGTGGAACCCTGGCTTCCCCTTGAGCATCGATGCCAAATGCCACAAGGATTTACCCC GTGATATCCAGTTTGATAGTGAAAAAGGAGTGGACTTTGTTCTGAATTACTCCAAAGCGTAAGTTTACGA GAACTGAGGGACTCTGGGCAGCCCCTCCAGTGGCTGGTGCTGGGGGTGGAACCCTCACTCCTTTCCTCAT GGGGTCCTTGGGTTGGGGGAACAGCCTAGCTGAGCCAAACGCTTTGATGATATGTTGGCCATAGAGTGGA TTCTCAACGCACAATTGCAGGACAACCGGTATCTTAAAAAAGGCATAACCAGAGGACTCCAGACACCAGA CATACATGTGTTTTTGGCCCAAAGCAGGGGTCTTTAGTTGGAATGCCTCCTCCCCATCCATATCTCATGC TCTCTATGGCCACTTCAAAGGTGTGAAGGCTTTGTGTCCAGGCTGTCACCAAGATGGCAGGTGCTATGGT AAGAATGGCCAAATTGCCAGTGCTGATCCCAGGACATATGTCCCCTGTTCCTCCGTCACAACCCCACGAG GGAGCCACAGTCATCATCCCCATTTTACAGTTGAGGAACTGAGGAATACGGAGGTTGACTACCTTCCTTG CCTAAGGCCCCCAGCTAATAAATGGCAGAGATATAGGTTCTGTGCACCTTTGTTTCATCCGAATGTCCGC AGGGCTTTTTAAAGCTTGCCCAGGCTATCGGGAGACTCTAGGCTGCTTGTTAAACATATGGATCCCCCGA CCCTATCCCAGGACTACTGAGTGTAGGGATCTTTAAATCTGCACATTGACCCTATAGGGAATTTTAAAAA TCATGTCAGTTTGGCGAAACTATTCCAATCAATAGAAAAAGAGGGAATCCTCCCTAACTCATTATATGAG GCCAGCATCATCCCGATACCAAAGCCTGGCAGACACACAACAAACAAAGAGAATTTTAGACCAATATCCC TGATGAACATCAATGCGAAAATCCTCAATAAAATACTGGCAAACCGAATCCAGCAGTACATCAGAAAGCT TATCCACCATGATCAAGTGGGCTTCATCCCTGGGATGGAAGGCTGGTTCAACATACGCAAATCAATAAAT GTAATCTAGCATATAAACAGAACCAATGACAAAAAACACATGATTATCTCAATAGATGCAGAAAAGGCCT TTGACAAAATTCAACAACCATTCATGCTGAAAACTCTCAATAAATTAGGTATTGATGGGATGTATCTCAA AATAATAAGAGCTATTTATGACAGACCCACAGCCAATATCATACTGAAGGAGCAAAAACTGGAAGCATTC CCTTTGAAAACTGGCACAAGACAGGGATGCCCTCTCTCACCACTCCTATTCAACATAGTGTTGGAAGTTC TGGCCAGGGCAATCAGGCAGGAGAAGGAAATAAAGGGTATTCAATTAGGAAAAGAGGAAGTCAAATTGTC CCTGTTTGTAGATGACATGATTTTATATCTAGAAAACCCCATCGTCTCAGCCCAAAATCTCCTTAAGCTG ATAAGGAACTTCAGCAAAGTCTCAGGATACAAAATCAATGTGCAAAAATCACAAGCATTCTTATATACCA ATAACAGACAGACAGCCAAATCATGAGTGAACTCCCATTCACAATTGCTTCAAAGAGAATAAAATACCTA GGAATCCAACTTACAAGGGATGTGAAGGACCTCTTCAAGGAGAACTACAAACCACTGCTCAACAAAATAA AAGAGGACACAAACAAATGGAAGAACATTCCATGCTCATGGATAGGAAGAATCAATATCATGAAAATGGC CATACTCCCAAGGTAATTTATAGATCAATGCCATCCCCATCAAACTACCAATGACTTTCTGCACAGAATT GGGAAAAACTACTTTAAAGTTCATATGGAACCAAAAAAGAGCCCGCATTGCCAAGACAATCCTAAGCCAA AAGAACAGAGCTGGAGGCATCATGCTACCTGACTTCAAACCATACTACGAGGCTACAGTAACCAAAACAG CATGGCACTGGTACCAAAACAGACATATAGACCAATGGAACAGAACAGAGCCCTCAGAAATAACACCACA CATCTACAACCATCTGATCTTTGACAAACCTGACAAAAACAAGCAATGGGGAAAGGATTCCCTATTTAAT AAATGGTGCTGGGAAAACTGGCTAGCCATATGTAGAAAGCTGAAGCTGGATCCCTTCCTTACACCTTATA CAAAAATTAATTCAAGATGGATTAAATACTTAAATGTTAGACCTAAAACCATAAAAACCCTAGAAGAAAA CCTAGGCAATACCATTCAGGACATAGGCATGGGCAAGGACTTCATGTCTAAAACACCAAAAGCAATGGCA ACAAAAGCCAAAATGGACAAATGGGATCTAATTAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTACCA TCAGAGTGAACAGGCAACCTACAGAATGGGAAAAAAATTTTGCAATCTACTCAGCTGACAAAAGGCTGAT ATCCAGAATCTACAAACAACTCAAACAAACTTACAAGAAAAAAACAACCCCATCAAAAAGTGGGCAAAGG ATATGAGCAGACACTTCTCAAAAGAAGACATTCATGCAGCCAATAGACACATGAAGAAATGCTCATCATC ACTGGCCATCAGAGAAATGCAAATCAAAACCACAATGAGATACCATCTTACACCAGTTAGAATGGCAATC ATTAAAAAGTCAGGAAACAACAGGTGCTGGAGAGGATGTGGAGAAGTAGGAACACTTTTACACTGTTGGT GGGACTGTAAACTAGTTCAACCATTGTGGAAGACAGTGTGACGATTCCTCAAGGATCTAGAACTAGAAAT ACCATTTGACCCAGCCATCCCATTATCGGGTATATACCCAAAGGATTATAAATCATGCTGCTATAAAGAC ACATGCACACGTATGTTTATTGTGGCACTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCAT CACCGATAGACTGGATTAAGAAAATGTGGCACATATGCACTATGGAATACTATGCAGCCATAAAAAAGGA TGAGTTAATGTCCTTTGCAGGGACATGGATGAAGCTGGAAACCATTATTCTCAGCAAACTATCGCAAGGA CAAAAAACCAAACACCGCATGTTCTCACTCATAGGTGGGAATTGAACAATGAGAACACTTGGACACAGGA AGGGGAACATCACACACCAGGGCCTGTCATGGGGTGGGGAGAGGGGGGAGGGATAGCATTAGGAGATATA CCTAATTAGGAGTTAATGGGTGCAGCACACCAACATGGCACATGTATACATATGTAACAATCCTGCACGT TGTGCACATGTATCCTAGAATTTAAAGTATAATAATAAAAAAAAAGACATACACGGAAAAAAGGAACACA AATCCACAGGAACAGTTGGTGGACTGTGCCTTTTTCCGAAGATGTCTTTAAGGGCATCAATATTTAAAGG AGAACAGGCTGGAAGGAAGAAAGGGAGGGCATGGTCACGTTACTGAATCCACATGTTGCAAAAGAAAAGG AGCAGGTAGGGGAATAGTCAGTTATGTATTCCTCTTGCGCTTAGTACATCAGCACTTGATAAGGTGAACA CCAAGAGCTACCTGTGGAGGTTTTCACCTTTTATCTGTAGCTATCTTCGTTTCTTGCATCACTCAGCTTT CAGCTTAATTTTTCCCTTTTGGCAGAGTGAATTGGGGTCCAAAGATTTTCATTTCCTTTTACACCTAGAA TCCTCTGAGGAGCATTAGCACCTGCTAGTGCCAGGCCAACCCCACACCCACAGATGACAGTCTATGAGGG TGGGACCCTGGCTTTGAGTCTGCACACCCAGCAGGTAGACGAGGCTGAGAACCCAGCCAGACTTCAAAGC TTAAAATAATATTATTTATTTCTAAACATTGTGTCGGTGTTTTGGGGGGTACAATAATCTATTTTAAGCT TCATGGCCATCCTGGGAGGTAAATAATATTATTGACCATTTCTAGGTGAGGAAACTGAGTCTCCAAGGGG TCAAGGTCAAGGAGTTTGCCTAAAGTCATTTAGGCAGAAATTGGCAAAACCAGGATTTGAATCCAGGTCT GTTTGTGTCCAAAGCTGGGGCATTTTTCTCCTACCACAATTGGGGTCTACTGGAGAGAAAAATTAAAACC TAACATCTGGATTAGTAATGCAGCAGTATCCACCATCTCCCTGGAAACATCACGGCAGTTAGGGGCTCAC TTCCCTTCCCCTACTCTGGGATTGGGATTGTTGATCAAAGCCATGTAGCTTTAGTGGGATAGGTCCCAGA CCAGGATGGGACAGGCAGGACAGAAGGCCCTTGTGAAAGAGACAGTTTGGAGGGAATAATAAGGATGGTG AGGTAGTGAGGTGGAGAGTACTGCCACCCAGTTTGGAGGGAATGGAGGAATACTGGACAGATGGACAATC AAACCGATGGACAGGCAGATGGATGGGTTGAGGGATGGATGATGAATGGATGGATGAAGGGAAGGAGGAA GGATGGAAGAAGAGGTGGATGGGGGATGGATGGAGAGATAGATGAGAAATTGATATACGGATGGATGGAT TCATGGATGGTGGATGGATGGATGGATGACAGATAGTGAGATGGATGGATGGATAGATGGGTGGATGGAT TGATGGGTGGATGGTGAATGGATGGTGGATGGATGGAAGTATAGACAGAGAGATGGATGGATAGATGGAT GGATGGATGGATGGAGGAATTAATGGTGGAGTGAAGGCCAGACTGTGCCTTTCTTATCTCTGTTCAGTGT TTCTGAAGGTCATTGTCATCTCTGTATCTCAGGAGCCTCTGTATCTTAGCAGCTGTCACAGAATAGGTGC TCATTAAATCCTATTAAAATGAAAGTGTGACCCACCTGGCCCCTGAGTGCCCCTGAGTGCCAGCTGGGTC ACAGTCCATTTTAACAGGGTTTAATGAGCACCTATCCTGTGGTATAGAAGGTAACTGTGCACCTCCTTTT CATGTATCCCCATCATGGCTAACAACAGCCTAGACATATGGTTCTCAATCCTGTGTGTTTAGTGTTACAG ACTCCATGCTGCCCACTCTGCACAAACTGTGGAACCAGGGGAAGTCCAGCACAGTTATATTTTAGGGCTA CTGGTGGATTCCAGTGTATAGCCAGGATTAAGAACACTGGCCTGTAATGCCTTTCTGGGCCTCCCCACCC CCCACATATGGTTGCATCTATTTGCTGAGTCAAGTCCATCTGCTGGGTCCCAGGGAGTGCCTCCTCCTCT CCCAGCTCCACCATCTCTCCTGAGTGAGGGCAGGAGCATCTTTCCAGCTGCCTCCCTGGGCTCCATCTCT CAAGACAGTGGGAGGGCTTATTCTCAAGTGCTTGTATAATTTGTTGGAGGCTCGCTCTAAAAAGTAAATA TAATTTCTTGGTTGGCTCAATTGCAGGTGAGAGCCCAGATGTCTCTGCCCAGAAATGGAGATACATCCAT AGGGACGCACCCGCCCCTGCCATCTCTCAGGTCCTACATGCATAGGATGCTCCACCGTGGGGAGCCAGCA GGGCTTTGCAGAGCATCTCTTGTCTCTGACCTAGCTGTTTCCTTTGCCACACCCACCCTCCCCACTTCTT GGCCAAGACATGGGTGAGGGGCCCCTTCTTGCAGAAGCTTCTAGAAGCCTCTGGCCCCAGTGAGGTCCCC TCCCCTGTACTCCCCAGTGCCGCCCACCCTGCCCTTGGCCCCAGAAGTGCTGCAGCCCACGTTTCTCCAC ATCGTCCTGTCATTAGCCCCTTGAGTGATGGCCTATTGGCAGGAGCAGAGCGAAGGAATCCTGAGAGGGG CCCTTCTGCCCCTCCTGGCCCAGCAGGCTGGACAGTAAGCTTAGCCCCACTCTGAGCACCGCCTCTGTGC TGGCACAGTGGATGGAGACCCTTGAGTTCTGCGGGGGAGAGAAGAGGTGTCCCTGTATTTGAGGAGCTGA GCCAAGGGGGCTGGACCACAAGGAAGCAGCTTAGAGGAGCCTGTGTGGGGATGAGGGGTGCCTGGGAGAG GGCCCTGGGCCGGTGGGGGTTGGGGGGACCCTAGGAAAGTCGTCTAAGTTCCCTGAGCCTCGGTGTCCTC AAATGAACAATGAGACCCGGCCCCAGCTCCTCCCCAGGGTTGTGAGATTAAAATGGGATCGCACACATCA GCCCCTCAGGGAAGTTTCTCCCTAAAGACAGCCTTTGTCTTCTCCATTCTTGGTTCAGGCCCTCTGGGAC CGCGTCTCCACCATCACACACCGGCCTAGGGCTGCACTCTTGGAAGGGCCCCTGCGCTTGCAGGGTGGGC AGGGGACCCTCGCTTCACCTGGGCGTCCTCTCTGATGGGGCCCAGGAAGGCTTTGCAGCCGGGGGCCATC TGACCAGGTCTTACTGGGCCCAGGCAGAGGTACGTGGGGCCTGGAGAATGGCACAGGGGGCTGCAGCGGA GAGAGACTGTGGGCACAGGTGTGGCGAGGCCAGGCCGCCGAGAGCCAAGTGGTTTGCGAAATTTCCTGGT GGTGTGGAGGGAGGAAAAGCTGATGTGTTCACCTCCCCACTCGCTGTTTGCAGCCTGGAAGACGATTGCA GGGGGTGGCAGGGCTGAAAAGACAATGTCCTCATTAAAGGAAATTGAGAAAGAGAGTTTCCTTCCCAGTG GGGCGGGACAGTGCAGAAATGCGGCCGGTCCTGGAAGAGGTGGGGGCGAGGGGTCGGGGGCTCACACGCC CTGCGATTTCCTCCCATGAGAATGGGCGGGGGCAGCTCCGGGAAGGGTGGCGGATGGAGCCGCCCTCTCC CCAGGACCACAGGGGCGCTTTCCAGTGAAGGCGCCGTAGGAAACGCCAGTCTGTGCCGCAGTGTACGTAG AGGCGCTATGAGCCCGAGTTTCCCACGTCCAGGGACAAACTGGGAGCCGTGACTGTCAGGCCGCGCGGAG GCTGCCCTGGCCGCCTTTGCGGTCAGGTGAAGGCGCAGAGGCAGGGAGGCCGGGCGAGCGCAGGCGGGCG GAGAGCAGACCACGCGGAAGAGGCCGAGAGAGAAAGCGGGGCACCCGGCCGGGGGGGTCATTTACAAGGG ACGCTGGGCACGAAGGAGGCTGGGGCGAAGATGAGTCCAGGGGTTGGGTTGAGAGCGCTGCGCAGCCGGG CTGAGAAGAGAAGCTGACGAGTGACTCCCGACAAGGGACGGGGGAGAGGGAACCTGGGGGCAGGCAGAGG CCTAGGGGGTGGGCTCTGAGGGCAGCCACTCCCACCGGCCCTCCCCCAGCCCCGCAGGCCAGCCACATGC CCCGTGCTCCAGACGACCCAGCTACATGGATGGCAGCGTCCTGAAGGGGGATGATCGGTAGGGAGTGGGT GCGGAGGCTCACGCCTGTAATCCCAGTGTTCGGGGATTCCCGAGCGGGAGGATCGCTTGAGCCGGGGAGG TGGAAGCTGCAGTGATCTGCGCCACTGAACTCCCGCCTGGGCGGCAGAGTGAGACCCTGTTTCAAAAGGC ACCAGGGGTGTAGGGAAGGAGCGATATCCCCCAGGCAAGGAAGGCTGCGGAGGGGCCAGGCCAGGAGAGA AGGGCCCTGAGCTCAGTGGACGGGCAGGGTGCCTGTGGAGGAAGGGAGGGACGTAGCAGCAGGAGGAAGG GTGAGGACCCAGGCTGGGGATCGGGAGAAGTGATGGCGGAGGAAAGAGAGGCCGGAAGAGGAGGGGGCCT GCTGGCCTGGCACTGGAAAGCAAAGCGTGGGTTTGTATATGGGAAGAAGACCACATCCCCTCTTATCGTC ATCCCAACTCAGAAACCATTTGGCCCCAAGTCACCAAAGCACTCATAGGAACCACTTTTCCTGTGACACA AGTAGGATTCTCCCACTTTTAACTTCCCAAATGCTACCCGAAAGCCTCTGAAATCCTTGGAAATTTAAAA AATAATCCCCTTCTATTAACTGATGCCTATAAAACATATTGACTTTCATTAAATTTTGTTATGAAATCAG GGATGTGTCCCATTGTAAAATAAATTTGTTTGGAAAATGTAGGGTGGTATCCCATCTAAAAATCAGACGA GGCTAGAAAATTTCAATTTTATTTGCTAAGGTAGCATCATGTTGTTAAAAATGCATCATAAAATAAGACC AAGAGTTAATACAAAGCATGAAGTCATGTTTCCCTCAAAAAAATGATTTGTTCTGTAGTCAAATTAATTT GGAAAACATTGCAAACTCTTCAGCAGTGGTTCTCAAAGTATAGCTTGCGTCAGAATCCCCTGGGGCCCTT GCTAAAATCTGGATGGCTACACTCCCCGCCTAGAGTGGGTTAAACTCAGTGCCCACTGGCAGGAAACTGA AACTTGGCTGAAGTCACCGAGGAGGCCTTCCCCGTTAAACCTCTGGCTGGCGACAGCTTGGTTTCCTCGC CGCTGCTTCTGAGTAATTCTGGCACGCAGTTCCTCCTAGCCACCTGCTGTACCTGGAAGGGGGCCAGCCC TCCTCAGCAGGCTTTGCTCCTGCCCTGCACAGCACAACTGTGGCGTAAAAAATGGAAAAGCTGGTAGCAG AAGGAAAGAGCAGGGAGACAGAGGTTAGGTGAACCTCAATGGCCTCATTAAAGCAAATTGAGAAAGAGAG TTTCCTTCCCAGTGAGGCGGGACAGTGCAGAAATGCGGCCCGTCCTGGGAGAAGTAGGGGCGAGGGGTGG GGGGCTCACCGGGCACATGGCCAACAGCTGGTGCCCAGCCTGGGCCACAGTTTGGCACAGGAGAAAGCTG AAGATGCAGGAGAAAGCTAGGTCACTGCCCCTAGGCCAGGTGATCAAGGTGGCTGTTACCTGCCTGTGTG GCCTTGAAAAAGCCTGGTGCCCTCTCTGGCTTGCAGGGTCCTTCTTTTTACAAAAGCGGGTCTTCGAAGC CCTGAATATTCCAGTTATCTGTAAGGATATAGAAATATTTTGCCTCTAGATGACATGTAAATATGTTCCT CCTAACTCCACTTCTTCCTACATCTGTGGCTTCTTCTGAGAACTACCAGACCCACCCTGTTTTCAGAGTA AACCTCCTGTTTTGAGGTCAAACAGACCCAGCTGGGTAATTGGTGACTCACTCCTGGTTCCTCCAAAGAA CAGGGGCAAGGGACCACCCGGGACCTCAGGTGCCCCAGCACAGGACCTCTTTCTGGGGCACCCTCTGGCA CTGGGCCATCTTCAGGCCCTACAGGGCTCTCGGGGCCTGCGTAGGCCTCTCATCTCCCAGAAATAAGTTC TTTTCCCCACCCAGACTGACACCAGATGCTACAGTGAGGTTTACCCCTCCAGCTTGACAAGCATTCCTAG CCCAGAACACTCAGCTGACGAGGGGTGCTGGGGGAGGAAGGAGGCAGCAAGGCTGAAAGAAGCTTCTCTG GGTATTCCAGTGCCTGGCTGCTGGTCGTAGCCATGGTGAGACCACAGCAGCCTCCCTGGAAGCAAGCACC TGTGTAAAAGCCCCTCCTTCCCCACAAGGGGCTGGATCCAAGTGAAGAAGGTACCAGAAGGACTGGAAGA TGATGCTGGTATTATTCGACAGCTCCAGGGTGCTGTAGCACTGAGCACCTACTGTATGCAGCCCATCACA AAGCCAGCCACACTGCCCAGGCTGTGCCATGGCAACTTCCAGCAGTACACCCTCTCGGTCACCTGCAGGC TCCTTGTTCATCCTGACACATGAGGAGAAAAAGACAGTACTCACAAAGGCCTCTAGCCTTGTGGCCCCAG GACCCTCTCCTGAGCATCATGGCCTCCTAGGAGACCCAGGGTAGCCAGGACAAAGGAGAGAAGCATTTGC TAAGCTAAGAAAGGATGGAAGGGGATTGCTGTTCTGCCTGGATGCACCCCTAGACCTGGCAGGGCAGGCA GGAGAGACCCCCAGTGTCTCTTGCTTATCCTAGGAGTTCCCCCCTGTGGTTGCTCCAGTTTGCTGCCTTC ATGCATGTTCACAGGGTGATTCCCCTGAGACAACAGAGCTGGGATGTCACCAAGCCCTGTGTCCCATCAG CCAGGCTCTCCCCAGCCTCCATCCTCTCATTCTGCTGGATCAGGAGGATGTGGGGAGGTCCCTGACTCCC CAGCTTTCCCCATGACAAGGTGTGTGTCTACAGCTCAGACCCAGCCATGCTCCACCTGAGAAGTGGGTCC AGGCAGAGCACTGGGTCCTGGCCACCTAGGGCTGCCTCCTCAGGGGTGGGCAGGAAGGGGAGCCACTGGA GGAGTGCCCCGGGCACAGTCCCCTGCACCAGGTGAGGTCACCTCTTAGTCCATGAGGCGATGCTGCATGA GCCCCTCTGGACACTAGAAGGCCTGGGCTCAATGCTGAGTAAAGTGCAGGCATGACTGTGCCCTCAGCAT GCATAGGGCAGCAGGCATAGATTCATACACGTGAGTTTGCACTTAAGCTGCAGTAAGAGCTACAGAGGAA ATGAACAGAGACAGCATCACTCCAGTGAGCCCTCCAGATACACCCCATGTGCGCAGTAAGAGAATGGCAT AGTCTATTGGGACAGCCACATCAAAATACCACAGACCAGATGGCTTAAACGGCAGATATTTGTCTCTCAC AGGTCCGGAGGCTAGAAGTCCAAGATTAGGGTGCCAGCCAATCCACTTGCTGGTGAGGGCCCTCTTCCCA GCTTGCAGATGTCTCTGTGTTCCCACAGCATGGTCACGTGGCAGAGAGAGGGGGACAGGGCATGAATAAG CCCTCGGTGCCTTCCTCTTCTTACGAGGATGCTAATCCCATCACGGGTACCCCACCCTCGTGACCTCGTC TAACCCTAATCACCTCCCAAAGGCCCCATCTCCTAATGCCATCACACTGGGGGTCAGGGCTTCAACACAT GAATTTGGGGAGCACAATTTAGTCCACAGCAGAAAAGAAAGGGGCACAGAGCATTCCAGCCTGAAGGAAA CAGATGTGCAAAGGCCCAAGGCAAAGGCCTGAGCTCTGAGGGGCAACCAGAGTCAAGGCTGAAGAGTGGG CAGTGATTGAGCACTGACGGTGGAGAGGCAACAGGCTATCTTGTTAATCTCAGTCTTTTGTGTGCCAGAG AGAGAAACTGAGGCACAGTGTGTCATGGTGAACACTGGGCAGCACTCCCACGCTCCTGTCCTGCACTCTG CAGGGTTATGGAGGAAGCCTGGGAAGTCTCTCCCCTCTTTTCCACCTTTCCTGGACCCATCCCACACCCT GCCTCCTCCAGGAAGCCCTGGGGATTGCTCATACACTCACATCTCACTCCTTAGTACCTGCAGCCTGCAT TCTGAATTTAGCAAGCTCTGGCCTTGGGTTTCTATTTTCTTGTCCTGTGCAGTGAGCATTTGGAAACTTC TCCTCAGCACCAAACACGGAGCCATTTAGCAGAAAATACATGAGTTTTCAAGTCAATTGAACTGTTCATC GCCCCAAAAGCCAGGCAACACGGTAGAGCAGCTGGATCTCTGTTCGTAGAAGCTTTCTCAGGGACTGGCC CACCGAGTGGGGGACTGCAAGTGCCCGATGAGTGAATGAATGAACACATGTGTGAATGGAATTCAAGGCA CTGCAGGCTATTCTGGAGGGTACTGGCCTGTCTCTTCGACAGGTGAGGTGCAGTAGAACAGCATCCCGTA TAGATGCCAGTTTCTGACCTGGTTCTGAAAAGCCAGTCACCTACCTCTGCAGAGCTGCCTGGAGGGGGCG GGGGTTGTGAGGACCCCTGAGAGCTTGGTGTGAAGGGGCTCTGCAGAGGGAGGCATGGCTAGTGTGCGCA AGGTGACCTCTCTCCTGGTCTGCAGGATGGAGAACCTGTTCATCAACCGCTTCATGCACATGTTCCAGTC TTCTTGGAATGACTTCGCCGACTTTGAGAAAATCTTTGTCAAGATCAGCAACACTATTTCTGGTGAGTGT GCCTCTGGGGGCCCAAGTGGTGCTGGGGACAGGGGATGCTGCTCTCCTGTCTGATACTTGCCGGGAAATT GACAAGGGCCTTCCTGCCTGCTGCAGCATGGGGGCCTCGCTGCCACCATGCCACCCTGGACAGCACCCCC TACACTCCACACCTTTTACCATCACTGTGGTCACCCTTGTGCCCAGAGGTTTCTCCTCCTCAGATATTCA AGCTCGAGCACCCTCAACCTCATTTCACTATCAAAAGTCTCAAAAGTATCAGAACTTTTTCTTGGCACAA ATCAATCATTTGTGCTTCTGAACAGAGCAAAGGCAGAACTTGGCTTGTGTTTTAGGTATTTACACAAAAG CAACTTTGGGTTCCTTTGGACTAGGATGTGTTTGATGAGAGCACTAGCTTCATAGTGGCCAGTCATGGCA TGGGAAGGACGTTAGGAAGGCAGGAATGGCTGGACAAGAAGAGGTGCTGAAATCAGGACATGGGGAACCA AACTTGGCAAACTGCCCCCAGGGACTCTCCTCCACGCCCTCCTTCTTCCATCCTGGACACTCCATGCTGG GCTGAAGGACCTGAGTGCTCCAGGAGGCTTCTGAGCCACGAAGGGCCAGCTCAGGTATGATGAGTTGGTG CCACAGCCTGACCCAGTGATGGGCAGGGGGCAGCAGTTGGAGCTGTGCCCATCCAGGGAGCACTCGGGAG AGGAGACCAAGCAGGGACTCTGCTCTTAGGTGAGGTCAGGAGGGCCATGGCCCTGGCTGCCCTCTACTCA GAGCTCAGGGTGGGCCTCGCTTTTCTCCTGGTAGAGCGGGTCATGAATCACTGGCAGGAAGACCTGATGT TTGGCTACCAGTTCCTGAATGGCTGCAACCCTGTGTTGATCCGGCGCTGCACAGAGCTGCCCGAGAAGCT CCCGGTGACCACGGAGATGGTAGAGTGCAGCCTGGAGCGGCAGCTCAGCTTGGAGCAGGAGGTCCAGGTA GGGGTTGATGGGCTGGGGAAGTGGCCAAGGTCACAGTCTGTCAGGTGGAAGCCAGTTCCTCCTGGCCAGT GCTCATAGGCCACCAAGACGCTAACTGCAGGCCCATCTGGCCTACAGCAGCCGCTTCCTTTTCCTGGCAG CAGTGTCAGCCAGGGTCCTGGGCATTATGCAGACTGTCTTGTGCAACATCAGAGGAGGAATTGCGGGGAA TGTTTCTCCATGATGCTCGAGTCTGGGAACATAATGTCAATATTTTCACTATCAGTATCAATAATTACAG GAGCTACCCTTGATTAGGGGCCTGTGGTGGGACAGGCATTGTGACAGGTGCTTTACACACAAGGTCATCA GTTGTCACCCACCTTGCAAAGGGGAGAACACTGGAGAAAGAAGCAGACCTTGTGTGAGAATAAAAAAGGG GCACGAGGAGAAACCCAACAGAATGGTTGATTTTCTCGTTAGAAATGCTGCTGCCCATGCTCCTGTCGCA CCCTCCTCCCCACCCTCACCTGCAGACTCAGCTGCCTCCGGCTGCAAGGCTGACCTAGTCTTGAGACAGA AGAAGTTCAAACCAACTCCACCTGGATCTGGTGGGGCTCAGCAACAGGCGCTGGCCCATCAGCCTGCCTC TTCCCCATGGATCCAGCGTGATGGGGCCTCCTGCCACCCAGGCCCTGCTGCCTATCCCCAGGTGTCCAGG TGGCCTCTGCTGCTTCCAGTCTTTTGAGCTCAGCTTACCCTGAGGCCCTAGTTGGAGAGGGATGGTTGGT GCCCTTTAGAGATAAACCTACAGCCCCAGTACCTGGCCCACCTGAATCTAGAGGGCCACCCACCCAGCTG AAGTCCCTGGGCAAGTCTCCTGCCCCAGTGCAGGCAGTGTTTCCTAACCTCCTCCTCCTCCTGCACCCAA CCAGGCCCAGAACACTTCCTGGTCATGTGAACAGCTGACAGTTACAATCCCCCACACACTGAGAGAGCAT CTGTGTTCCTGAGTGGACTGAATTGCTAGATGTAGTAACATTGATTTGGTGGCTATAGGTTTCAAACTTC AAGTCAGAGATCATAGAACTTTAAGCCATATAGAATCCTAGAATTGGAAGACTCTGAGCAGCCATCTCTG CACCCAGCAGCCAAGGAGTGGCCATCCTCAGCACCTGGCAGGGCATCAGCCTCCCACTGGGAGTCCCGGC CACCTCCAGGGCACGTGGGTTATGAGTCACCTTTCCTTTGAGCTGACCCACCCCTCACTGACTAGACTCT TAAACACACACTGCCCCGTCTAATACACACCAGCATGATTCTTAATCCCCACAGTCATTCACGCTGCCCA TCTGGCAGCACCTTAATGATCTACAGCAAGCTTGTGGCCTACTAAAAACGCCTCCATTGTTTTTTAAAAT GTGCAGTTATTTTCCGGATCATGAATAGAGAAATTGTATCCCTGTTGTTGGTATTGATTCAGTGTTCCAG CTCAAGTTTGAGTTCTTAGACTTTATATTTGGATTCTTTGGTTTCAAATCACAAAAATCAACTCCATCTG GTTTAATCCAAGAACTCTATTGGCTCAGGCAACAGTAAAAAGCAATGCTAACTCATTTGGGACCAGGGCT CAGATCATCCCCTGCACTGTCTCTCTCTCGCTCCATGTCTCAATCCTCTGCCTCTGGTGATTTTTTCCTT AGGAGGGTTTCCTTATGTGGAGGTAAAAAATGATCACCGGCAGCTTCAGATTTACCTTCCACCAGCTTAG CAAACACCACCCACTCCCAGCAAGAAAGACCCTGTTTCCCAATGCTCCCAGCAGATGTCTTAGGCCATCC TCGGGCCTCACTGATTCTGTGAGCCAGTGCCCACGGCCAGGAGAATGGAATACACTGACCTAGAGGGGAC AGGGACTCTAGACAGGCAAAAACTCCACTGTCAGAAGCAGAATCCTAAAATGTCAGAACTGAAAGGTAGG CCCGCCCCTCGTTTTCCAGAAATATGAAAGGGAGGCTTGGGATAACAGAGAAATGCTGCAGGCATTGGCC CCAAATCTCAGGCCTCCTATTCCCAGTATCACCTTCACCAGCCTGGGTGGTCTCAAGATTGGATTAGCAG CCATTCCTTCTGGGTAGAGTCTGATGGTCACTTCAGCTCTCAAAGTCCAGCTATCCAGCCATAGTCCTAG AAGGCAAGACATCACTGTGCCCGACCAACCCAAGGGTCTCCACCTGCCCCCCTCAACACAAGGTGCCCTG AGTGCCTCCGCGGGGATAGTCCCCGTCCCCACCCCTGCTTCCCCCGCCCATCGCGACAGATGCTCAGAGC TCATCCCTGGTGTCACACCACATAAAGGAGGAGGGCGGTGGCCAGGCTCCGAGCTCCTGCCGTCCTGGGT GGGTGGCTTCTGTCCTGCGTGCCGCCGGGCAGCCCGGGGGTCCTGCGCGCGGGCGCGGTCGGTGGAGCTG CAGGGGGGCGCTCTGGGATGTCTCCAGGCAGAGTAGATACTGACCCCTCCGCAGCCGGGACCCTCACCCT TTCCTTCATCACTCAGGAAACAGAAAAGGCTTCAGAAGGAGCGGCCATGCCCCCGGCCTAAGCGCTGCGT TCCCGGCCCAGCAGGCCTACCCTGCACCTGGCGTTCCTAGGGGCCCCTCTGCGGGACCCACTGCGCGGCT CGCAGCGGCCGCCCGCCTCCCACTTCACCGGCACGCTCGTTGCGTGTCGAGGTGTGTTGACTCCTACAGC AAAGGGCACGGATCCGCGGGTCAGCAAGCCCGACGAATTTACACCAATGACCCGCCGTGTCGCCAGTCTC AGACCAGGGCACAACACGCCAACCCTGCAGACCACCCCCACCTCCCCAGCCACTGCAGACCCTTCCCCCT CTGCTTCTGCAGCACCTCTCCCGAAACACGCTCATTCCCGCCCCCGCAGACCTTCCCTACCTCCTGGAGA CCCCCCTCAACCCCTGTAGAGTCCCCTGCCCGTGCAGAATCCCCTCCCCCTTCCCCCGCAGCCCCCCTAC CCCACCCGGCGGACAGCCCCGCCTCGCTTCCTGTCTCTTCCTCCCAAGGGAGACCCCTGTCCTGGCTCTG ACTGGGGTTGAGTTCGCCAGTTTTGACTTATGTGTAGAGTCCGGCAGCATCATTTTTTGGCATTTAACTC GTCACATCTATTTCACCTAACCTCTTTCTTCTTAGTAAACTGACACTCGGGTCGGTCTCTCATCTTTCGT GCCAGTCAAGCAGGTTTCAGACACCACAAATGCCGAATGAGCTGCTGCCATTCCTTCATCTTACCCCGAA CTGCCACAACCTGTGAACACCTTCCATGTGAATCAATCAGCCTTGGAGTCAGAGGAGAGAAGTACACATT CTGAGCTCCGCTGAGTCGCAGGAAAGGGAGAGGGGTGCCCAGAGGTCATCACTCTTTCCCCAGGCCTGAT TTTTGGTCCGTCTGCTGAGCCTGATTTGGACACATCTCTCTGCCTCCTGCAGCAAGGGAACATTTTCATC GTGGACTTTGAGCTGCTGGATGGCATCGATGCCAACAAAACAGACCCCTGCACACTCCAGTTCCTGGCCG CTCCCATCTGCTTGCTGTATAAGAACCTGGCCAACAAGATTGTCCCCATTGCCATCCAGGTAGGCTGCTG GGGGGCACACCTTTCTGAGCAGCTCAGTCCTCTGCGATCCAGGGCTCCTGGGTGGCTCCATTCACACTCC AGCTGAGGAAGCTATGTCTTGAAAGACACTAGGGCTTCCTGCAGGCCCTGAGGTGGGCTGTCCATAGGGG CGGAGAGGGTTCTACTCCCCAAGGCACACTTGAGAAGCCCCTGGCCAGTCGAGGCACACTGTGGAGGACC TGCCCTGGGATCATATTCTGCACTCTCCACCCCAGCACCCTGACCAAGGGCCCCCAGTCAAGGTGCTGCC AGGGGCCAGGCAGGTGAAGCTGTGGACTAAGCTGGAGACCAAGACCACTGAGGGGCACCATGGGTTCTGG GGTCAGGAACCAGGCCAGTCCTGGTATGCCACCTTTGATGATGATGTGAGTTCTTATGTCCACCGGAGAT GAGGCAGGAGGAAGAGGGAGACCCTGGAGGAAAGGCAGGCGGGCACAGGGCTTTGTCTCCCCCTGTTCCT GGCACCAGCCTGCTGCCAGGCTGGGAGCTGGTGTGCAGACAGCAGGGGCCAAGGCCAGGACTGGACTGGG CATAGGTCCCTGGGAGTAGGGAGGAACTGCGCAGAGGACACCGTGGGAGACTGGCAGATGAGCATTCAGC AAATAATGTCCATGAACTGGACCTTGGGAGCTGTGGACACAATAGCAGCTGGATAGGTCAGGCACCAGCC ACATGCCAAGGCTATCCTATGGGTTAACCTGCACAGTCCGCAATCCCTTACCCTCGATTCTAAATCTAAA AAATCTGAAAACTGCTGCATATTTCAAAACTGTGCAGCAAATTCATTGTTTGTAAACAAACCTTCTTTGA AGCAATAGGTGAGGTTATTTAGAGGCTTTTTCCATTCAATGTGATATGTATGTGGATCACTGCAGAAATA CTGCTCTGTTCGATTGTAAAATAGTATGTTGCCCTAGACTGGGGGTGGGAGGGGGTATGGCACATAATGA AGTATACCCACTGCTAAAATCCTAAAAATTCTGGATTCTGAAGCACATTTGACCACTGGGGTTTTAGATA ACCTATCTTTATTTGTGTAATCATCACCACAACCATCCTAGGTAGTGGGCTCTATTGATGTTGATCATTT TACCCAGATAAGAAAACTGAGACACAGGTGCCCACAGCCAGCCACAGAGCTAGGATTCAAGCCAGGTCAT CTGACTCTAGATTCCAGCCTCCCCACAGTCTCCCAGGGGCACGTAGCCTCAGAGGAGCTTCCTGTCTGTT ACCAGAGAGAAGCCCTGTGCCTAAGAAACTGAAGCAGCAGGTAAAGGGACAGGTGACCTAAAAGAAGACA AAATTGCTGGGAGATCCCCGGAGATCCCAGGCACCACTGATGGTGCCTTCAAAAGCTTGGCTCAGAGATC TCTTGGAGCAGCCTGGAGTCAGGGGCCTAGCTTAAATTCCAGTTCAGCCACTTGCTAGCAGGCTGTGGGA CCTTGAGCAAGCCACAGAATGTTCCTGGGTCTCTTTCTTCTTCTGAAAATGGAAACTTTGCAAACTATAA AGACTCAAGCAAATGAAAGCCAGAGGATAGTAAATCCAAGATCTGGTTCTTTGAAAGGTCCAAAAAATAA TAATAATAACCTCCTCATGAGGCTGATGGAAAAAAAGAGATAGAAAAAAAAAATGCAAGATTCGGAATAA AAAAGGAATCATAAAAAGAGTAATTATAGCCAGGCACCATGGTGGTACACAACTGTAGTCCCAGCTACTT GAGAGGCTGAGGCAGGAGGCTCACTTGAGGCTGTAGTGTGCTATGATCACACCTGTGAATAGCCACAGCA GTCTAGCCTGAGCAACATATCAAGACCCCGTCTCTTAAAAAAAAAAAAGAACAGTAATTATGATTACATA TTTTTTAAATGAGAGTAATATGGCAAAAATTTGAAAAATTAGAGAAATGGATAAAAACCTAGGAAAAGAT AAATTAGAAGAAATTGTAGAAAATAGGCCAATTTCCATATAGTGATTGGAAACAGACCTACACAGCGAGC AGCTGAGTCTCACCCAGCCACTAGACAGCTGACATTTCCAGGGCTCTTTATCAGCCCCAAATTGATCATA TAAAGCTGGTGTAAGCTTAGTTCTGAAACTGGATACAGGCAGGCTTCAAAAGAAGGCTGAAGACCAATCC AAGTATTAAATAAAGATTTAAAAGAAAACTAAAGGTGATATTAGCGAAGTGAGTGCAGCAGTGTATTAAA TGACTATATGTAATAACCAAGCAGGGTTTATTCCAGATATTTCAATATCAAGAGAGCTACCACCATAATT TATTATACCCATAAGGATAAAGTTTATGATTATATCAATTCACACTAAAAGGGAATTTAATAACATTTAA TAGCCACAACTAATAAAAATTAATAGGAGGAACCTTACTTTATATGATAAAGATAGCTAACATCAAAAAG GTGCAACTCTAATGCCATTTCCATTAAAATAATAAGAATGCTGATATCACTGTTTTTATTCAACATTATT TTAGAGGTCATACCACATGATAAAACAGGAAAACAATCAATAAACATATTGTCAAAGAACAGGGAAGATG ATCTTTTCTGGTAATGCTATGGTAGACCTAGAAAACACAAGAGATTCTAATTTTTTTAAAAGCTACTAGA TTAATAAATTCATTTGGCAAAGTGTTTAGATAAATATATTTCTCAAAAAAATCAATAGCCTTTCTCCATA CTAACAATAAAATATAATGCCCATATAAGGAAAAACTATAAAGTTATTTATTTATTTATTTATTTATTTA TTTATTTATTTATTTGAGATGGAGTTTCGCACTGTCACCCAGGCTAGAGTGCAGTGGCGTGATCTCGGCT CACTGCAACCTCCACCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAG GCACCTGCCACCACGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGCATTTCACCATGTTGGCCAGG CTGGTCTCGAACTCCTGACCTTGTGATTTGCCTGCCTCAGCCTCCCAAAGTGTTGGCATTACAGGCGTGA GCTACCGCACCCGGCCAACTATAAAGTTATTTTAAAGGATATACAATGAACTCTTAACAGTGATTTGATA TTGGGGAGGAAACTGTAAAAATGTCAGTTCTACCAAATTCTATTATAAAAACTTAATGCACTTCCAAGTA AAATTTCAGCCAGAATTTTTTATCTTTCTTGGTGGGGGTGTGGTGGTGGTGAAGAGGAACTAAAAAGGAG AGAAAACAATTAAAAAATTGAAAGATTCATATGGAAAAAGAAATCTAGCATAGTCAAAAATTTTTTGAAA AAAATTAAAACCACATAGAGAGGCAGGGCAACCAAGTGAGACCTCATGTCTTAAAAAAAAAAAAAATTAA TAGAAAAAATTAGGTATGGTGGCGCATGCCTGTAATCCCAACTGCTCAGGAGGCTGAGGTGGGAGGATGG CTTGAGTCCAGGAGTTTGAGGCTGCAGTGAGCCATGGTCGCTCCACTGCACTCCACACTGGGCAACAGAG TAAGACCCTATCTTTAAAAAAAAAAAAAAAAAGTAAAAGAAAACACAGAAGGAACACTTTCCTTGCTGGA TTTGTAAGGTTACTGTTAAGCAGACACTGTGCTTGAAAACAGAGAGAATTGGGGGACAGTATAGAGTAAG ATCCAGAAATGGACTCCCCCACAGAGGAATTCAGTGTATCACAATGGAGGTTTTTCAACTCAGTGAAAAA GGGATATTATTTTAATGATGCTATCACACTGCCTTTGCATGAGAAGAAAATTAAATTGGACTGCTCTGTC ATGCCATTTACAAAAATAAATCTCATCATGTAGAGGAGTTGCTTAGAAGAAAAAGAAAAAATTCAGATGA AGTAAAAATTAAAATGAAAAAAGTAAACGAATTTAGAAAAACTAATTACGCAGACACTCAGAAGACTTTT AGAAGGAAAAGGAAACCAAGAAGTTATAAGGGGAAAGCTAAGCATATTTGATTATGTAATGTTTTAAAAC TTGAGTGATAAACCATAAACAAAGCCAAAAAGCAAAACAGAGATTAGGGTGAGTAACCATAACAGAAGTG ACAGCTAAGAGATGCCTATCTATGATACACAGGTAGCTCCTTTACATTGACGGGAAAATACCAATACTCC AGTGGAAAAATGAGCAGAGAATATGAATAGGCAATTCACAAAAGAAGAAATGTAAATGGGCAACCAGCAT ATGGAAAAACTCCTAACTTCACCTGTAGTTAGAGAAATGCAAATGAAAGTTAACAATGAGATATCATTTC TGACATGCCTGGTTGGAAAAACAAAGGGGTAACTCCCAGACACCAGCAAGGACGGAGCCCCATGCTCTGC TCATGAGTTGTTGCAGCCTGGCAGTGTTCACGGGATAACTGGTGGGCCTGGGCAGCCCAAGGTCAGAGCT TCGGCCAGCACCGGAGCAAGGTCAGAGCTTCGGCCAGCACCGGAGCAGATCCCACAGCGCCTGCTGTACC AGGTGCATGTTGCAGTGGGCGGTCAGAGGGTCCTGGGGTTGAGGCTGTCGTGGCGAGGACAGTTGTGTTA CCGAGCTGGACTGGGATCTGCTTGCCCAGTGCAGCAAAACCAAACACTGAGATTGGGATATAATCTACGA GAACACAAGGCATTTATTGCGGGGACCAAAAAAGGAGAATTGGGCAGCTCACTCTTAAGACCGGAACTCC CTGATGGCTTGCAGGTAAGGGTTTTTAAAGGCAGAGTGAATTTCAGGAATTGCAGAAGTTAACAGGCAAA ATCATTAATCAATACATGGAGGGTACACATTGGTTTTGGCCTAAAAGGGCGGGATATCTTGAAGTGGGGG TGGGCTTCCAGGTCATAGGTAGATTCAAAAATTTGTTGTTTTGAAATTGGTTAAGGAAGAGAAGTTTCAT TTAAAAATTTGGGTTACCAGAAAGGAATGTTAGCTGTGGCTTGTGGGCGGGACTTCCCCCAGGCCCCCCA GGAAGAAATTTAGAACAAAGAGCCTGCTCAGAGTTCAGTCCTCAGTTCCGTCTTATCTGAGGTCTCTGTG CCAGTGGATCGGTTTGGTGGGGGTCTGGGTTTCTGAAAAACAACTCAGAGACACATGTTCAGGGGTTCTC TTTAGTTTCCAGAGGGAACCAAACAGCCCAGGACTCTGGCTTCCTTGGCTGTTGTTTTAGGCTGCTGTTA CCCTCTTGTTTGTCAAGTTGCTCATTTATTTCTCAGGGCTAGCTAGGTGCCTGGAACTTCCCTTCAAGGA ACTCGGGATTTTCCTTCATTTCCATGCCCTGTTGCGGGGCTGGGGGGCTACAGTGCCCTAAGAGGAGGCC CCTGCCCCGTCTCAATTGGAGGAGCACTGGAGGGGACTTTATTGTTTAAGTGTTCTGACAGCCAGTAGCA CTGAACAGGTGTGCACCAGGAGAGTGAAACTGTCTGAGGAACAGTAGGGCAGGCACTGTCTACTCGAAAA CATACCCAAACCCCCAAGGCTCAGCCTTCGCTAGCAGCCACTCAGCAGAAATGAAAGCACAAATGTGTGT GGGTAGCAACAGGAGCATAGTTTGTGATGGGGAAAAAAATTGAAAACAGTCTGAAGGCAGAAGAGGATTG AGTGAGTGAGCCCTTCCATGTCCTCACCATAAAATGTTGAGGCGTCTTTGAAAGGAATGCTTTGGTTCCC TTCCAGCTGACCTGGAGGGGTCTCCACAATGAGTTAACAGTGGAAAAACAAGACACAAGGGACCGATAAA GGATACATATCTGTCGTATACAAATAGCTCCTTCAAACTGCTAAGGCAATGGGCATGGTCTCACTTATGT AAAATGAATGCAAGGATGCAGCAGGCCTACTGTGCCAGCATGGGGACACAAGGACGCAGTGTCACCAGGT AGGAACACAGTGATGGCCCAGTGGGGGACAGGTGAGCAAAACAAAGAGACAGATGTTGATTATAATCATA TTCAGTTGATGGAAAATTGGACAGATAAATGTGCACACATGCAAAGACCTATGAAAGGAGGCTCCCCAGA ATTTGGTGGTTATCCCTGGGCGCTGGAAGATGAGATGATGTTTTCTTTCTCAGGCTCTCCTGTCATGACT CAGATTTCTTTTTACGATAAGCACATATTCTTTTCTAATCAGAAACGCAAAGCTACTTCCTTACCCAAAA AACAAATTTAAGAAACACAAATTGCTCAGGGCAAGTTCTGGCATCCCATGGCAGGCCAAAATCCTGGACA GGAGTGGGAGGATGTGAAGGATGGGTTGGGGAAGGCCCAGCTCAGTGGTACAAGAGCTCAAGGAGATGGG CAGGTGAGGCCCGGTCAGGCCGGGAGGTGAAGAGAAGCAGAAGGGAGAGTGATGGGCTGAAATAGGCAGA GCACTGGGCCCATCCTCATTCAGCTCTTTTTTTACTGGTCAGAACAGTTTTTTTTTTTTTAATATATAAA ATTTTAGATTCAGGTACATGTGCAGGTTTGTTACATGGTTATATTGCATAATGCTGGGGTTAGGCTTCTA TTGAACCCATCACTCAAATACTGAGCATAGTACCCAATACCCAGTTTTTCAACCCTTTCCTCCCTCCCTC CCCTTCCTGGAGTCCCCAGTGTCTTTTGTTCCCACTTTTATGCCCATGTGTACACAATGCTTAGCTCCCA CTTATAAATAAGAACATGCAGTATTCGATTTTCTGTTTCTGGGTTAATTCACTTAAGATTATGGCTTAAG TGCCAATCCTAAGCTGCATCCATGTTGCTGCAAAGAACACGATTTCATTCTTTTTTATGGCTATGTAGTA TTCCTTGGAGTACATGTATCACATTTTCTTTATCTGGTGCCACTATTGATGGGCACCTAGGTTGATTACA TGATTTTGATATTGTGAACAGTGCTGCAATAAACATATGTGTGCCTATGTCCTTTTGGTAAAACAATTTC TTTTCCTTTGGGTAGGTACACAGTAATGGGGTTGTTGGGTCAACTGGTAATTCTATTTGCAGTTCTTTGC AAAATCTCCAAACTGCTTTCCACAGGGATGGAAGTAATTTACACTGCCACCAACAGTGTGTAAGCATTCC CTTTTGTCTGCATCCTGCCAACATCTGTCATTTTTTTACTTTTTAATAATAGCCATTCTGACTGGTATCC CTTTGTGGTTTTAATTTGCATTTCTCTGATGATTAGTGATGTTGGGCATTTTTTCATATGTTTGTTGGCC ACTTGTATGTCTTCTTTTGAGAAGTGTCTGTTCCTGTCCTTTGCCCACTTTTTAATGGTGGTGTTTTTTC TTAAGTTCCTCATAGATTCTGGGTATTAGTCGTTTGTGGATGCATAGTTGCAAATATTTTCTCTCATTCT GTAGGTTGTCTGTTTACTTTGTTGATAGTTTGTTTTGCTGTGCAGAAGCTCTTTAATTTGATTAAGTCTC ATTTGTCAATTTTTGTTTTTGTTGCATATGCCTTTGAGGTCTAGTCATAAATTCTTTGCCTAGGAAATGT CCATAAGATTTTTTCCTAGGTTTTCTTCTAGAATGTTTAAAGTTTGAAGTCTTACATTTAAGTCTGTAAT CCATCTAGAGGTAATTTTTGTATATGGTGAGAGGTAGGGGCCCAGCGTCATTCTTCTGCATATAGGTAGC CAGTTTTTCCAACACTATTTATTGAATAGGATGTCCTTTCCTTATTGTTTATTTTTGTTGATTTTGTCAA AAATCAGTTGGTTGCAGGTATATGGCTTTATTTCTGGGTTCTCTGTTCTGTTCCATTGATCTCTGTGCCT ATTTTTGTACCAGTATACCATGCTGTTTTTGTTACTGTAGTCTTGTAGTATAGTTTGAAGTCAGGTAATG TGATGCCTCCAGCTTTGTATTTTTGCCTAGGATTGCTTTGGCTATTCGGCTATTTTTTGGTTCCATATGA ATTTTAGGATTTTTTTTTCTAATTCTGTGAAAAATGATGTTGATAATTTGATAGGAATTGTGTTGTATCT GTAGATTGCTTTCTTCCAACCCATTAGCTGGGATGTTTTTCCATTTTTTTGTGTCATCTATGATTTCTTT CATCAGTGTTTTATAGTTCTCTCTGTAGAGCTCTTTCACCTCCTTGGCTGGATACATTCTTTGGTATTTT ATTTTGTGTATGGGGGACTATTGTAACTGAGATCACCACGTTCCTGATATGGTTCTCAGCCTGAACCTGA ACATTGTTGGTGCATAGAAATGCTACTGATTTTTAGGCCAGGCACAGTGGCTCACGCCTGTAATCCCAGC ACTTTGGGAGGCCGAGGTGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGA AACCCCGTCTCAATTAAAAATACAAAAATTAGCCAGGTGTGGTAACACCTGCCTGTAATCCCAGCTACTT GGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTGCGATCACACCACT GCACTCCAGCCTGGGTGATAGTGAGACTCCGTCTCAAATAAAAAGAAATGCTACTGATTTTTGTACACTG ATTTTGTATCTTGAGTGTAGAAAGTCAAAAGTTTTTTTTTTGTTAAGGAGTAAATTATGTGTTAGAAATA ATAGTTTTTTCTAAAGACTAACTTTTTTTAAGCCTTTTCGCTTTGTGCTAATAACTTTTTGTTAAGCCCT ATCATATGTAGCTGTTAGATATAAGGGAATGAGTACATTCTATGTCCTTGTACTTTAACCAAGATATTTG TGCTGGACGTGCTCACAGGCATGTCCCAGCTTGCAGCCCATGCCCCTTCCTTATTTGGAAATGTTATTAC TTTTCTAAGTCCTTTCATAAGCAACTTCCTCTTTTCCTTTGTCTTTCCACTGCTTTTACCTATTTAGAAA AGTTTTAAGTTATTAGCCAGTCGGGTTTTAGTTTAGACTGTGAGGTTTGGCTCCAGCCAATGGAGACAGG ACACGGTAGCAGGGACAAGCTGCGTAAGGAATAAAAATTGCTTCTCTCCATTATTCAGGTGTGCTCTCGC CATTGTTCCATCTGCGAGGAGCACCCTTTCTGCAGAAAGTAAAATTGGCTTGCTAAAAAAACTTTTTGTC TAAATGCTGATTTTTCCTTGCAGTACCGAGGAACAAGCATTCTGTTTCTAAACAAGCATTTTACTTATAA CATTGAGACTTTACTGAAGTTGTTTATCAAGTCTAGGAGTCTTTTGGAGGAATCTTCAGGGTTTTCTAGG TATAGAATCATATCATGGATGAACAAAGATAATTTGACTTCCTCTTTTTTTTTTTTTCATTTGGATCCCT TTTATTTCTTTCTCTTGCCTAATTGCTCTGACTAGGACTTCCAGTACTCTATTGAATAGGAGGGGTGAGA GTGGACATCCTTGTCTTGTTCCAGTTTTTAGGGGGATTGCTTCCAATTTTTGCCTGTTCAATATCATGTT GCCGGCTGAGCTCTTTACCTACTGTGTGACTTGGGAGAGCTGCTAAACCAGCTGGAGCCTCAGTTTCCCC CCATGTAAAATGGGTACAGCAAGGAATATCTGCCTTGCAGGGTCAAAGTGAGGATTAAGTGAGATAGCAT GGGTAAAGCCCCTAGCACACAACAGGGGGGCTCCTCGGCCCCAGAGGATGTCAGGAACATGTCAGTGTCC CAGAGCCATCAGGAACATGTCAGTGTCCCAGAGCCATCAGGAACATGTCAGAGCATGTGGGGACATGTCA GAAAGTGTCTCAGAGCATGCCAGGCAGCCCAGCATTCTAGGGCACAGATCAGGTATCAGTGGCCCAGGCA TCTCATGCAAACGGGTGTGGCAGTGGGGACCCTGAGAGCTGGGACTCTGTAAAAGGGACAAGAGCGTAGT TCTGTGAGAACCTGGGTGCAGAGTTCTGAGACCTTCTAATTTTTCAAGAAAACCAGGTCATTCAAATTTT TATGTGAAACTGTCTGGTATTTAAAAGCAGCCAACTAATCTCAAGTATAAACAGACAGGCACGCCTAATG TGCAAGTCACACTCTGCTCTCCCTCCTCCCTCCCCCCTCCTTGGTCCTCAGGGAGTGCTGAGGCTTCTGG GGTCTCTCTGACCAGGGTGGAGCCACTGGCCACCAGGGCTCTGGAGCACTTGGGATTTGGCTCGTCCAAA CCAAAACCTGCTGCAAGTGCAAAGTTCACACCTGATTTTTAAGACTTAGAATAAGGAGGTGGGGAATGTG AAATATCTCATTTAATAGTTTTAGATTGGTTTCATGTTGAAGTGATAATATTCTGGATATATTGGGTAAA ATAAAATTATATTATTCACCGGCATTTCACCTGTTTCCTTTTATTTTTATTAATATGGCTTCCTGAATAT ATACAATTCCATGTGTGGGGTAGCATTATATGTCTATTGGACAGCACTGTTTTCGAGGGAGAGACGCCCA AGGACCCCACCTTCCACAATACTTATAGCAAGTGACACAGCTGTGTGCTCTGGGACAGTTCTCCCTCCCC AGCCATGACCACTGTGCTGCAGTGACACTGGTCTTTCCCAGCACCTAAAGTCTGGCCATGCCCCTTCCTG GCCGCTCTTGGCTGCAGCCCTGCCACCCACCTCATTCTTTCTGTCAACCCCTCCAATACCCCATGTCTTC ATGTAAAAATGGGCAATGCCAGCACCTGCTGCCGGCTCCCGTGAGAACTCACTGTCGGGTGCTGAGGCTG TGCTGGGCTCTCAATAAGGGGGCAACGTGCAGGGCTGCTGGCATGGAGGGACCTGGGGCTGGGTGCTGGT GTGGGGGCACGAAAGTGAGGCTGTGTGTACAGAGGCATCAGCAACCAGGTCACCACAGAGCTTGGGGATT TTATTTTCTGGCATTAAGAGGTGATTGAGGAGGCAGTTAACATGACATGATTTGCATTTTGGAAAAGAAA AAAACTCACCTTGTCCCAGTGTGGAGTGGAAACTGGAAAGGGAAGACAGGTCCAGCCTCTGCTACAGGAG GTGCCTGGCCACAGGTGTGGGCTCCAGGCAGAGCTCAAGCTGCAGACCCTGATCTGGGAGGCTCAGTACC AGGAGGGCCCCAAGCCTTTAAACAGGAGGAGCTGACTTAGGGCAAGAAAAGAAGACAGGAGCACCAGGGC AGACCCTGGGGAGCTCCAGCATTTCAGGGAAGAGGAGAGGGAGGAAAGTATGAGAGACCAAGGAGAGGCA GTAGAAGAGGGAGCAGGGCAAGGAGGGAAGAGGGGGACAGCGATCCTCCCCCTCCGCTGCTGGGCCTTCG GCCTGCCCGCTCCTTCCATGCTGCCAGCTCCTGAGTAACTGTGAGCCGAGCGATCACTGTCCCCACATGA CAGATGCTGAAGCCGGAGCTTAGAAAGCCCAGTGTGTCATCCAGAGTCATGCAGGTTGTAAGTAATATGG CTGGGACAGGAAATACCACCGCAGGGCCCTTTACCCCCTCCAGGCTCTTCTGATTCCAAAGTCACTGTTA AAGAAATTCAGATACTTCTGGAACTTCCCAAGAGGCGAAGTTCTCCAACAACTATACTCTGAAGTGAAAT ATAGCAGTGTGTTTCCTTTCCCCCAATGTATCAGCTCAACCAAATCCCGGGAGATGAGAACCCTATTTTC CTCCCTTCGGATGCAAAATACGACTGGCTTTTGGCCAAAATCTGGGTGCGTTCCAGTGACTTCCACGTCC ACCAGACCATCACCCACCTTCTGCGAACACATCTGGTGTCTGAGGTTTTTGGCATTGCAATGTACCGCCA GCTGCCTGCTGTGCACCCCATTTTCAAGGTACAGCCAGCTACCGCCCCACCTGCTATGGGAGGGCATCTG AGATGTGGAGTGGGAGGGATCACTGACATCCCACAGGGGGACCTGTGGCTGGGAGTGGGTGGCAGAAAGG GAGCCCTGGAGAGATGTTCTCAGAGTCAGTAATGCCCCTAAAGGAAGAAAACAGCTAGGAGCCTGCTGTT CCCCAGGACACGCGGCTGGGGCATGGGCCTGACACACGGGCCTCGCTGGCCAGCCAGTAGAGTTGGAAAA GGCAAATGAGTTCATGGTGATCCTCGGCTGATGCTGATGGCCGCCCCTGCCATCACTCTCCGTCCCTGTT CTCGAATCCTACAAGCATTGGCTGCTGGGGTGACTGCATGCTAAAAGTACCCATGTGCCTCAGTTTCCTC ACCAGTAAAACAGGTCAAATAGTACAGCTGCCTTACAGAATGATGGTCAGATTAAGACAGTGAACTCAGG GAGCAAAGAGGTAAGCATTGTACAAGTGCTGGCCAGGACCCTCTGAATCATTATCATGCTTAGTAAGCAT CAGAGGGGTGCAGGCCTCCAGCACTTATTCAGCAGAAAGATCAGCACCCAGCCTTCACTTCCTCCCTGCG CCCAGCATCATCCTATAGGGCAGGCCTGGGTGGGGGAGCTGCGGGTCCCTGAGGCACCAGGTCACCTGAC TGGGCCCCCTCTGAGGCCTCCTCCTCTCCCCTCCCCAGCTGCTGGTGGCACACGTGAGATTCACCATTGC AATCAACACCAAGGCCCGTGAGCAGCTCATCTGCGAGTGTGGCCTCTTTGACAAGGTGGGTGCCCTCCTA CCCTACTTGTTGCCTGGAAGAGCCCAGCCTGGCCGCCTTCACTCCCTATCTGAGATCTAGACACCCTTTC AGGAGGCCTGGAAGGGTGAAGGCTGGAGTCTGCTCAGAGCACTGGCTCCAGCATCCTCCTGATGTCTCCA GCCCGTGCCATTCAGCCAGGAGCACTCCTCCAGGCGCACCACCAGGTCTTCCTTCTCACTGATGGCTCCT GGTCCCCTCCTCCCACCCCTCCCCTCTCCCAGCCTCTGGGACCTGGGTGTAGACCCCCCTCTGGAACACA CTCCTTATGGCCCCCTGACCTCCTACGCACCAGGAACCTGTGTCTGCCTCTTAATCTGCCACACCCCTGC CACCCTGACCTGGACCTCCCCAGCACTCTGCTTCCCGGGTCCCAACCCTCCCAACCCACTGTCTCCTGCA TCGGGGACTCCAGGCCCTGCCCAGCCCTCGCATCCCTCAGGTAGCACCCCACCTCGTTTTGAGCCCTCTG TAGCCTTACCAAGCTTGGACTCTCACATGGGCCCTTGCCCCAACCTTCCTCCTTTCCCCAGCCCATTAGT GACCAGGCCAGATGACCACTGAAGTTGAGACACTGTTTGGGCTGCAAATGACAAAACCCAACTCAAACCA GCTGCAGCTGGACAAGACATGCCTTATCTCAAATACCTGGACACAATAGAGGGTCGGGGGCCTCAGCCAG AAATGGATCCAGGGACTCAAGCAATGCCCCAGGGTGCATGCACACTGGCTCCCTCTTTCTGTCTCTTTCA CCTGTGTTGGCATCACACTCTCCTGCTGCAGACAGGCCCCCATGGGAGAGGGCACAGGAGCTCATCATAG TAGCTCCACCTCAGGTTCTCATGTGGCCATTATCTCCCAGCCGCATCTAAACAGAAAGTGCTGGGGGGCA GCTCTGGTTGGTCCTGCTTGGGCTGAATGCCCACCGTGGACCAATCTCTGGCACCCCAGCACCCAAGTCC TTCTTCAAAACCTCTGTGGCACCGACAGCCCAGCCCCCTGGGTGTATTTGCATGTGTGTGTGTGCACGTG GACACACATATGTGCCAGTGAGCTTGTGAGTGTGTCTGCATCACTCAGAAGCCGGGATCGGGATCAGGAC CAGGATCCCTCCTTGTGGGTCTCTCCAGCCCTCACCTGAGCACACAACAGGCCCTCAACAGAGTTGCATG GGTCCTGGAAACTGAGGGTCACTGAGAGCAATGACTGAGGGTCGTGTGCTCAGCACTAGAGCAGACTTCA CAGCCCAGGCCCGCTGGTGCTGGGGTCCCCCACACACCTGCCCACGCCTGCTGCCCTCCTGTGGCTGGGA GCGCACCCTTCCCTCTTGTACTCTGCAGCCCCACGGTTCAGTCCCTTGCATTGGATTGGGCGGGAGGCTC CTCCCTAGCACCTCTCCACCCGGCTGCCCTTGTCATTCTCTGCGTTAAACATCCCTCCCCCATCTCACAG GACAAGGGCTTGCACCTCTGCCTGCCTGGCCTCCTCGCCTCCCCTGGCACATTTCCTCAGGGATGGGTCT GGACAGCTGTGGGAGGAGCCACCCGCTCAGGGCACTCTACCTCCCACTCCAGGCCAACGCCACAGGGGGC GGTGGGCACGTGCAGATGGTGCAGAGGGCCATGAAGGACCTGACCTATGCCTCCCTGTGCTTTCCCGAGG CCATCAAGGCCCGGGGCATGGAGAGCAAAGAAGACATCCCCTACTACTTCTACCGGGACGACGGGCTCCT GGTGTGGGAAGCCATCAGGACGTGAGCGCCCGCGGGGCGGTGGTCCTGGGGGAGGAGCCGGGACCCCTGC CTGACTACCTGGGGCGGGCCTGGCCCCTCCACCGCTAGCGCTGAATGGGGACGGGGTGGGGGAGTCCCAG CGTCCGTGAGGGGGTTGCCGCCGGGCACCGCTCCGCAGACCTGGCTGGGTCGCCCACCCCGGCTGCGCCC CCTGAGCCAGGTTCACGGCCGAGGTGGTAGACATCTACTACGAGGGCGACCAGGTGGTGGAGGAGGACCC GGAGCTGCAGGACTTCGTGAACGATGTCTACGTGTACGGCATGCGGGGCCGCAAGTCCTCAGGTAGGGCC TCCGGGACGTCTCCGGACCCGGCTCCCCCGCAGTCGGCAGCGCTGGCCCCTCCGCCACCCCTCCGGGGTG TCCTGCCCAGGGTGCCCTCCGGCCTTGGGGCAGGGAATCCGGGCACGGGGTGGGCGCCGGGCCCTGGGGT CCTCAGGGACTGGGCCTCAGCCCGCCGGTGGTTCCACCCTAGGCTTCCCCAAGTCGGTCAAGAGCCGGGA GCAGCTGTCGGAGTACCTGACCGTGGTGATCTTCACCGCCTCCGCCCAGCACGCCGCGGTCAACTTCGGC CAGGTAGGCAGGGCCGGGCCCGCTGGGCAGGGCTCCCTTCTCAAGGCCGCTGCCTCCTCCCCCGCCCCGG TTCTGCACGCGTACTGCACCCTCGGACAGCCTCGGGGCCTGGCACGGGACTTGCAGGATGGATTCTGCCC GCTCAGCCAAGGGCGCTGGCCGCGGGGAAAGAGGATGGACGGACTGCAGGGCCCGCTGGAGTTGGGGGGC ACGGGGAGGACGGGGCCCAGGGGGCAGCTGGGCAGCAGGGCTTCGGGGGTGCCCACGCTTGCTGGCGGTC GTCTCCGCAGTACGACTGGTGCTCCTGGATCCCCAATGCGCCCCCAACCATGCGAGCCCCGCCACCGACT GCCAAGGGCGTGGTGACCATTGAGCAGATCGTGGACACGCTGCCCGACCGCGGCCGCTCCTGCTGGCATC TGGGTGCAGTGTGGGCGCTGAGCCAGTTCCAGGAAAACGAGGTGAAGCTGGGCAGGGCGGGGCACAGCCC CAGGTCACCCCAGGTTAAGCGGTTCCTCAGCCTCAGGGCTTTGTGACTCGGGCCCCAAGGCTCACTTGGA GCAAAGGAATCCTGACTTCCAAGGCTGGAAGGGCCCAGAAGGCTGCAGCCGCCACCAGGTCCCCCGGCCT CAGCCTGGACAGAGCTCAGGGTGTGCAGGGCAGGAGAGCACACAGCCCAGGCTTTGCTCACTGTCACCAG AGGGTCGTGTGTGACGCCCCCTCCCCCCAGCTATTGACAAAGTTCTTGCACATGTGTTTTACCCTGGTAC TCCAGAGGGAATGACCAAGAGTTTCCTGGGTTCCTTCCGGACACGTGCATCTCATTTAACCTAACAACTG AATCCGGTGTGTCTTCGTGGATGCACCCGCTTTGGGGTAGCTCAGTACTGCATAGAATGGCCGGACCAGT CCAACCTGCTCCAGACTGCTGGGTGTCTGAGTTGTTCCCGGCCAATGTGTTGGTCCCTCACTGGACATCC TTGTTTTTGTGGCTTTGCACATGTGTTCAGTATGACCGCACACATTCCTAGCAGACAAATTCCTTGGTCA AAGAATATTGATACTGAATTGCCCTCCACAAACTAAATTCAAAATCCCATTATCAATAGCCTATGTTTCT TGGACCTTTCCAGCTCAGAAGCTTTGTGATCTTAATCCAATACAGTATTTTTTTAAAATGATATCTAGCT CTGCCCCGCAGACATCTGTGTGAGAATGCAAATAAGCACAGGACCCCAACAGGGCAGCCACCCCTTCAGG CTCCCTGGCCCGCTTTCTGCCTTCCTGGGCTGGAGAGGCCAGTGCTGGCCCCAGCGCCCCTGATGGGAGG TGAGAGTGCTGCGCAGGGGTGGCCCAAGACAGCAGGATACCATGGCTGCAAACACCAGCAGCCCCCAGCT TCATCTGCATCATCTCGTAACCACTTGGCAGCAGGCAGTTATTTTCCCACTTATCCATGAAGCCCCAGCC CTGGAGCCTTCCTTAGAGAAGCAGGTTGGAGGCGACGACACTTGCCTTCCCGAGGCCCTCTTGTCAGGCA GCAGAGGGTGAATATGGGGAGGTGAATAGATGCTCCCTCCTTCATCTCCCAAACGGTGGCTGGCCCCTTG GGATGAGACAGGCCTGTCAGTTTACACGGGTAGTGGATTGACCTATGTGTGTGTCCATGTCTGGGCCCTC AGCTGTTCCTGGGCATGTACCCAGAAGAGCATTTTATCGAGAAGCCTGTGAAGGAAGCCATGGCCCGATT CCGCAAGAACCTCGAGGCCATTGTCAGCGTGATTGCTGAGCGCAACAAGAAGAAGCAGCTGCCATATTAC TACTTGTCCCCAGACCGGATTCCGAACAGTGTGGCCATCTGAGCACACTGCCAGTCTCACTGTGGGAAGG CCAGCTGCCCCAGCCAGATGGACTCCAGCCTGCCTGGCAGGCTGTCTGGCCAGGCCTCTTGGCAGTCACA TCTCTTCCTCCGAGGCCAGTACCTTTCCATTTATTCTTTGATCTTCAGGGAACTGCATAGATTGATCAAA GTGTAAACACCATAGGGACCCATTCTACACAGAGCAGGACTGCACAGCGTCCTGTCCACACCCAGCTCAG CATTTCCACACCAAGCAGCAACAGCAAATCACGACCACTGATAGATGTCTATTCTTGTTGGAGACATGGG ATGATTATTTTCTGTTCTATTTGTGCTTAGTCCAATTCCTTGCACATAGTAGGTACCCAATTCAATTACT ATTGAATGAATTAAGAATTGGTTGCCATAAAAATAAATCAGTTCATTTAAAATGGG Download Select all
Length	71946
OMIM ID	152390
HGNC ID	HGNC:435
Unigene ID	Hs.89499
Ensembl ID	ENSG00000012779
PharmGKB ID	PA46

mRNA Information

mRNA ID	NM_000698.3
Exon	join(1..254,8308..8506,21680..21761,38016..38138, 49866..49972,50785..50957,54443..54589,66255..66458, 67169..67255,68863..69041,69241..69362,69553..69653, 69941..70111,71333..71944)
mRNA Sequence	>240 CCGGGGCCAGGGACCAGTGGTGGGAGGAGGCTGCGGCGCTAGATGCGGACACCTGGACCGCCGC GCCGAGGCTCCCGGCGCTCGCTGCTCCCGCGGCCCGCGCCATGCCCTCCTACACGGTCACCGTG GCCACTGGCAGCCAGTGGTTCGCCGGCACTGACGACTACATCTACCTCAGCCTCGTGGGCTCGG CGGGCTGCAGCGAGAAGCACCTGCTGGACAAGCCCTTCTACAACGACTTCGAGCGTGGCGCGGT GGATTCATACGACGTGACTGTGGACGAGGAACTGGGCGAGATCCAGCTGGTCAGAATCGAGAAG CGCAAGTACTGGCTGAATGACGACTGGTACCTGAAGTACATCACGCTGAAGACGCCCCACGGGG ACTACATCGAGTTCCCCTGCTACCGCTGGATCACCGGCGATGTCGAGGTTGTCCTGAGGGATGG ACGCGCAAAGTTGGCCCGAGATGACCAAATTCACATTCTCAAGCAACACCGACGTAAAGAACTG GAAACACGGCAAAAACAATATCGATGGATGGAGTGGAACCCTGGCTTCCCCTTGAGCATCGATG CCAAATGCCACAAGGATTTACCCCGTGATATCCAGTTTGATAGTGAAAAAGGAGTGGACTTTGT TCTGAATTACTCCAAAGCGATGGAGAACCTGTTCATCAACCGCTTCATGCACATGTTCCAGTCT TCTTGGAATGACTTCGCCGACTTTGAGAAAATCTTTGTCAAGATCAGCAACACTATTTCTGAGC GGGTCATGAATCACTGGCAGGAAGACCTGATGTTTGGCTACCAGTTCCTGAATGGCTGCAACCC TGTGTTGATCCGGCGCTGCACAGAGCTGCCCGAGAAGCTCCCGGTGACCACGGAGATGGTAGAG TGCAGCCTGGAGCGGCAGCTCAGCTTGGAGCAGGAGGTCCAGCAAGGGAACATTTTCATCGTGG ACTTTGAGCTGCTGGATGGCATCGATGCCAACAAAACAGACCCCTGCACACTCCAGTTCCTGGC CGCTCCCATCTGCTTGCTGTATAAGAACCTGGCCAACAAGATTGTCCCCATTGCCATCCAGCTC AACCAAATCCCGGGAGATGAGAACCCTATTTTCCTCCCTTCGGATGCAAAATACGACTGGCTTT TGGCCAAAATCTGGGTGCGTTCCAGTGACTTCCACGTCCACCAGACCATCACCCACCTTCTGCG AACACATCTGGTGTCTGAGGTTTTTGGCATTGCAATGTACCGCCAGCTGCCTGCTGTGCACCCC ATTTTCAAGCTGCTGGTGGCACACGTGAGATTCACCATTGCAATCAACACCAAGGCCCGTGAGC AGCTCATCTGCGAGTGTGGCCTCTTTGACAAGGCCAACGCCACAGGGGGCGGTGGGCACGTGCA GATGGTGCAGAGGGCCATGAAGGACCTGACCTATGCCTCCCTGTGCTTTCCCGAGGCCATCAAG GCCCGGGGCATGGAGAGCAAAGAAGACATCCCCTACTACTTCTACCGGGACGACGGGCTCCTGG TGTGGGAAGCCATCAGGACGTTCACGGCCGAGGTGGTAGACATCTACTACGAGGGCGACCAGGT GGTGGAGGAGGACCCGGAGCTGCAGGACTTCGTGAACGATGTCTACGTGTACGGCATGCGGGGC CGCAAGTCCTCAGGCTTCCCCAAGTCGGTCAAGAGCCGGGAGCAGCTGTCGGAGTACCTGACCG TGGTGATCTTCACCGCCTCCGCCCAGCACGCCGCGGTCAACTTCGGCCAGTACGACTGGTGCTC CTGGATCCCCAATGCGCCCCCAACCATGCGAGCCCCGCCACCGACTGCCAAGGGCGTGGTGACC ATTGAGCAGATCGTGGACACGCTGCCCGACCGCGGCCGCTCCTGCTGGCATCTGGGTGCAGTGT GGGCGCTGAGCCAGTTCCAGGAAAACGAGCTGTTCCTGGGCATGTACCCAGAAGAGCATTTTAT CGAGAAGCCTGTGAAGGAAGCCATGGCCCGATTCCGCAAGAACCTCGAGGCCATTGTCAGCGTG ATTGCTGAGCGCAACAAGAAGAAGCAGCTGCCATATTACTACTTGTCCCCAGACCGGATTCCGA ACAGTGTGGCCATCTGAGCACACTGCCAGTCTCACTGTGGGAAGGCCAGCTGCCCCAGCCAGAT GGACTCCAGCCTGCCTGGCAGGCTGTCTGGCCAGGCCTCTTGGCAGTCACATCTCTTCCTCCGA GGCCAGTACCTTTCCATTTATTCTTTGATCTTCAGGGAACTGCATAGATTGATCAAAGTGTAAA CACCATAGGGACCCATTCTACACAGAGCAGGACTGCACAGCGTCCTGTCCACACCCAGCTCAGC ATTTCCACACCAAGCAGCAACAGCAAATCACGACCACTGATAGATGTCTATTCTTGTTGGAGAC ATGGGATGATTATTTTCTGTTCTATTTGTGCTTAGTCCAATTCCTTGCACATAGTAGGTACCCA ATTCAATTACTATTGAATGAATTAAGAATTGGTTGCCATAAAAATAAATCAGTTCATTTAAAAT GAAAAAAAAAAAAAAAAAAAA Download Select all
Length	2581

CDS Information

Location	join(105..254,8308..8506,21680..21761,38016..38138, 49866..49972,50785..50957,54443..54589,66255..66458, 67169..67255,68863..69041,69241..69362,69553..69653, 69941..70111,71333..71512)
CDS Sequence	>gi\|371877526:105-2129 Homo sapiens arachidonate 5-lipoxygenase (ALOX5), transcript variant 1, mRNA ATGCCCTCCTACACGGTCACCGTGGCCACTGGCAGCCAGTGGTTCGCCGGCACTGACGACTACATCTACC TCAGCCTCGTGGGCTCGGCGGGCTGCAGCGAGAAGCACCTGCTGGACAAGCCCTTCTACAACGACTTCGA GCGTGGCGCGGTGGATTCATACGACGTGACTGTGGACGAGGAACTGGGCGAGATCCAGCTGGTCAGAATC GAGAAGCGCAAGTACTGGCTGAATGACGACTGGTACCTGAAGTACATCACGCTGAAGACGCCCCACGGGG ACTACATCGAGTTCCCCTGCTACCGCTGGATCACCGGCGATGTCGAGGTTGTCCTGAGGGATGGACGCGC AAAGTTGGCCCGAGATGACCAAATTCACATTCTCAAGCAACACCGACGTAAAGAACTGGAAACACGGCAA AAACAATATCGATGGATGGAGTGGAACCCTGGCTTCCCCTTGAGCATCGATGCCAAATGCCACAAGGATT TACCCCGTGATATCCAGTTTGATAGTGAAAAAGGAGTGGACTTTGTTCTGAATTACTCCAAAGCGATGGA GAACCTGTTCATCAACCGCTTCATGCACATGTTCCAGTCTTCTTGGAATGACTTCGCCGACTTTGAGAAA ATCTTTGTCAAGATCAGCAACACTATTTCTGAGCGGGTCATGAATCACTGGCAGGAAGACCTGATGTTTG GCTACCAGTTCCTGAATGGCTGCAACCCTGTGTTGATCCGGCGCTGCACAGAGCTGCCCGAGAAGCTCCC GGTGACCACGGAGATGGTAGAGTGCAGCCTGGAGCGGCAGCTCAGCTTGGAGCAGGAGGTCCAGCAAGGG AACATTTTCATCGTGGACTTTGAGCTGCTGGATGGCATCGATGCCAACAAAACAGACCCCTGCACACTCC AGTTCCTGGCCGCTCCCATCTGCTTGCTGTATAAGAACCTGGCCAACAAGATTGTCCCCATTGCCATCCA GCTCAACCAAATCCCGGGAGATGAGAACCCTATTTTCCTCCCTTCGGATGCAAAATACGACTGGCTTTTG GCCAAAATCTGGGTGCGTTCCAGTGACTTCCACGTCCACCAGACCATCACCCACCTTCTGCGAACACATC TGGTGTCTGAGGTTTTTGGCATTGCAATGTACCGCCAGCTGCCTGCTGTGCACCCCATTTTCAAGCTGCT GGTGGCACACGTGAGATTCACCATTGCAATCAACACCAAGGCCCGTGAGCAGCTCATCTGCGAGTGTGGC CTCTTTGACAAGGCCAACGCCACAGGGGGCGGTGGGCACGTGCAGATGGTGCAGAGGGCCATGAAGGACC TGACCTATGCCTCCCTGTGCTTTCCCGAGGCCATCAAGGCCCGGGGCATGGAGAGCAAAGAAGACATCCC CTACTACTTCTACCGGGACGACGGGCTCCTGGTGTGGGAAGCCATCAGGACGTTCACGGCCGAGGTGGTA GACATCTACTACGAGGGCGACCAGGTGGTGGAGGAGGACCCGGAGCTGCAGGACTTCGTGAACGATGTCT ACGTGTACGGCATGCGGGGCCGCAAGTCCTCAGGCTTCCCCAAGTCGGTCAAGAGCCGGGAGCAGCTGTC GGAGTACCTGACCGTGGTGATCTTCACCGCCTCCGCCCAGCACGCCGCGGTCAACTTCGGCCAGTACGAC TGGTGCTCCTGGATCCCCAATGCGCCCCCAACCATGCGAGCCCCGCCACCGACTGCCAAGGGCGTGGTGA CCATTGAGCAGATCGTGGACACGCTGCCCGACCGCGGCCGCTCCTGCTGGCATCTGGGTGCAGTGTGGGC GCTGAGCCAGTTCCAGGAAAACGAGCTGTTCCTGGGCATGTACCCAGAAGAGCATTTTATCGAGAAGCCT GTGAAGGAAGCCATGGCCCGATTCCGCAAGAACCTCGAGGCCATTGTCAGCGTGATTGCTGAGCGCAACA AGAAGAAGCAGCTGCCATATTACTACTTGTCCCCAGACCGGATTCCGAACAGTGTGGCCATCTGA Download Select all
CCDS ID	CCDS7212.1

Protein Information

Protein ID	NP_000689.1
Protein Name	Arachidonate 5-lipoxygenase
Molecular Wt. (Da)	77852
Protein Sequence	>240 MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGE IQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHIL KQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFIN RFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKL PVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANK IVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMY RQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYAS LCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVND VYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPP PTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRK NLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI Download Select all
Length	674
Uniprot ID	P12814
Ensembl Protein ID	ENSP00000193403

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	272

Enzyme Information

EC	1.13.11.34
Name	arachidonate 5-lipoxygenase leukotriene-A4 synthase Delta5-lipoxygenase 5Delta-lipoxygenase arachidonic 5-lipoxygenase arachidonic acid 5-lipoxygenase C-5-lipoxygenase LTA synthase leukotriene A4 synthase
Class	Oxidoreductases; Acting on single donors with O2 as oxidant and incorporation of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2; With incorporation of two atoms of oxygen
Sysname	arachidonate:oxygen 5-oxidoreductase
Substrate	arachidonate [CPD:C00219]; O2 [CPD:C00007]; (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate
Product	leukotriene A4 [CPD:C00909]; H2O [CPD:C00001]; (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxyeicosa-6,8,11,14-tetraenoate
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
60	ACTB	32	NP_001092.1	in vitro	7929073
2885	GRB2	150	NP_002077.1	in vitro	85 856 057 929 073

Pathway Information

Pathway Name	Pathway ID
Arachidonic acid metabolism	hsa00590
Metabolic pathways	hsa01100
Ovarian steroidogenesis	hsa04913
Serotonergic synapse	hsa04726
Toxoplasmosis	hsa05145

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd01753	2-115	PLAT_LOX
cl00011	2-115	PLAT superfamily
pfam00305	125-666	Lipoxygenase
cl09510	125-666	Lipoxygenase superfamily
smart00308	4-107	LH2
pfam01477	4-108	PLAT
cd00113	4-109	PLAT
cd01752	3-109	PLAT_polycystin
cd01756	3-104	PLAT_repeat
cd02899	4-104	PLAT_SR
cd01754	Apr-52	PLAT_plant_stress
PLN02337	165-674	PLN02337
PLN02305	227-674	PLN02305
PLN02264	164-674	PLN02264

Ontology Information

HPRD ID	20
Molecular Class	Enzyme: Lipase
Molecular Function	Cytoskeletal protein binding (GO:0008092)
Biological Process	Cell growth and/or maintenance (GO:0008151)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P09917 DB00163 Vitamin E SmallMoleculeDrug
P09917 DB00179 Masoprocol SmallMoleculeDrug
P09917 DB00233 Aminosalicylic Acid SmallMoleculeDrug
P09917 DB00244 Mesalazine SmallMoleculeDrug
P09917 DB00471 Montelukast SmallMoleculeDrug
P09917 DB00586 Diclofenac SmallMoleculeDrug
P09917 DB00711 Diethylcarbamazine SmallMoleculeDrug
P09917 DB00744 Zileuton SmallMoleculeDrug
P09917 DB00795 Sulfasalazine SmallMoleculeDrug
P09917 DB00939 Meclofenamic acid SmallMoleculeDrug
P09917 DB01014 Balsalazide SmallMoleculeDrug
P09917 DB01017 Minocycline SmallMoleculeDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

Uniprot ID	DrugBank ID	Name	Type
P09917	DB00163	Vitamin E	SmallMoleculeDrug
P09917	DB00179	Masoprocol	SmallMoleculeDrug
P09917	DB00233	Aminosalicylic Acid	SmallMoleculeDrug
P09917	DB00244	Mesalazine	SmallMoleculeDrug
P09917	DB00471	Montelukast	SmallMoleculeDrug
P09917	DB00586	Diclofenac	SmallMoleculeDrug
P09917	DB00711	Diethylcarbamazine	SmallMoleculeDrug
P09917	DB00744	Zileuton	SmallMoleculeDrug
P09917	DB00795	Sulfasalazine	SmallMoleculeDrug
P09917	DB00939	Meclofenamic acid	SmallMoleculeDrug
P09917	DB01014	Balsalazide	SmallMoleculeDrug
P09917	DB01017	Minocycline	SmallMoleculeDrug

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO