Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| WWTR1 | 25937 | WW domain containing transcription regulator 1 | 3 | TAZ, DKFZp586I1419 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22470139 | 2012 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | real time RT-PCR,Colony formation assay,lentivirus-mediated RNA interference | Up-regulation | - | WWTR1 is an oncogene and has an important role in the proliferation of colorectal cancer cells and in tumor growth in vivo. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - |
| Chromosome | 3 |
| Location | 3q23-q24 |
| Start | 149235022 |
| End | 149421060 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 186039 |
| OMIM ID | 607392 |
| HGNC ID | HGNC:24042 |
| Unigene ID | Hs.477921 |
| Ensembl ID | ENSG00000018408 |
| PharmGKB ID | PA134899667 |
Protein Information
| Protein ID | NP_001161750.1 |
|---|---|
| Protein Name | WW domain containing transcription regulator 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 400 |
| Uniprot ID | Q96BK5 |
| Ensembl Protein ID | ENSP00000318966 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 89 |
| S | Phosphorylation | 87;- |
| S | Phosphorylation | 90;- |
| S | Phosphorylation | 105 |
| S | Phosphorylation | 93 |
| T | Phosphorylation | 98 |
| S | Phosphorylation | 117 |
| S | Phosphorylation | 393 |
| Y | Phosphorylation | 118 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 7080 | NKX2-1 | 2798 | NP_001073136.1 | in vitro;in vivo | 14970209 |
| 7531 | YWHAE | 5457 | NP_006752.1 | in vivo | 11118213 |
| 9351 | SLC9A3R2 | 5946 | NP_001123484.1 | in vitro | 11118213 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Hippo signaling pathway | hsa04390 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00201 | 127-156 | WW |
| cl00157 | 127-156 | WW superfamily |
| smart00456 | 125-156 | WW |
| pfam00397 | 126-155 | WW |
| COG5021 | 114-168 | HUL4 |
Ontology Information
| HPRD ID | 18202 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.