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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
LRIG1 26018 leucine-rich repeats and immunoglobulin-like domains 1  3LIG-1, DKFZP586O1624, LIG1 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
26159916   2015Cell line : -

Source : -

Sample Type : CRC tumor and normal tissue

No. of Sample : 46

Stage : -

-Methylation-LRIG1 is frequently methylated in human CRC and consequent mRNA and protein downregulation may contribute to tumor growth by activating EGFR/AKT signaling.


Gene Details



NC_000003.11 (66429221..66551446, complement)

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Gene Type protein coding
Gene Family Immunoglobulin superfamily / I-set domain containing
Description -  
Chromosome 3
Location 3p14
Start 66429221  
End 66551446  
Strand -  
Gene Sequence

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Length 122226  
OMIM ID 608868   
HGNC ID HGNC:17360   
Unigene ID Hs.518055   
Ensembl ID ENSG00000144749   
PharmGKB ID PA38450   

mRNA Information


mRNA ID ?NM_015541.2
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS33783.1



Protein Information


      
Protein IDNP_056356.2
Protein Nameleucine-rich repeats and immunoglobulin-like domains 1
Molecular Wt. (Da)0
Protein Sequence

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Length 1093  
Uniprot IDQ5XXA6
Ensembl Protein ID ENSP00000319477  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd05763616-690  Ig_1
cl11960616-690  Ig superfamily
cd00096512-586  Ig
cl11960512-586  Ig superfamily
cd05745707-780  Ig3_Peroxidasin
cl11960707-780  Ig superfamily
cd00096710-775  Ig
cd00096616-686  Ig
cd05725616-689  Ig3_Robo
cd05729704-780  Ig2_FGFR_like
cd07693598-689  Ig1_Robo
cd05728603-689  Ig4_Contactin-2-like
cd05856706-770  Ig2_FGFRL1-like
pfam13895693-780  Ig_2
cd04968692-780  Ig3_Contactin_like
cd04978616-690  Ig4_L1-NrCAM_like
cd07693688-775  Ig1_Robo
cd05724605-689  Ig2_Robo
cd05737703-780  Ig_Myomesin_like_C
cd00116131-416  LRR_RI
cl23707131-416  LRR_RI superfamily
cd05725710-780  Ig3_Robo
cd04969707-780  Ig5_Contactin_like
cd05726616-689  Ig4_Robo
pfam13895604-689  Ig_2
cd05851692-780  Ig3_Contactin-1
cd05857704-780  Ig2_FGFR
smart00082442-490  LRRCT
cl15307442-490  LRRCT superfamily
cd05891703-780  Ig_M-protein_C
cd05748617-689  Ig_Titin_like
cd05748717-775  Ig_Titin_like
cd05724701-780  Ig2_Robo
cd05746617-688  Ig4_Peroxidasin
cd05894703-780  Ig_C5_MyBP-C
cd05747704-779  Ig5_Titin_like
cd05867616-690  Ig4_L1-CAM_like
cd05722600-689  Ig1_Neogenin
cd0011673-323  LRR_RI
cd05765707-780  Ig_3
pfam13927692-767  Ig_3
cd05746710-779  Ig4_Peroxidasin
cd05738714-780  Ig2_RPTP_IIa_LAR_like
cd04978707-781  Ig4_L1-NrCAM_like
cd04968605-689  Ig3_Contactin_like
cd05731618-689  Ig3_L1-CAM_like
cd05728699-780  Ig4_Contactin-2-like
cd05729617-689  Ig2_FGFR_like
cd05732699-770  Ig5_NCAM-1_like
cd05730706-780  Ig3_NCAM-1_like
cd05736711-780  Ig2_Follistatin_like
cd05765616-689  Ig_3
cd05726707-780  Ig4_Robo
cd04969618-689  Ig5_Contactin_like
cd05745620-689  Ig3_Peroxidasin
cd0011653-176  LRR_RI
cl2370753-176  LRR_RI superfamily
pfam00047707-764  ig
cd05744710-780  Ig_Myotilin_C_like
cd05893710-780  Ig_Palladin_C
cd05747598-688  Ig5_Titin_like
cd05738616-689  Ig2_RPTP_IIa_LAR_like
cd05849710-774  Ig1_Contactin-1
cd00116253-421  LRR_RI
cd05893617-689  Ig_Palladin_C
cd05743707-771  Ig_Perlecan_D2_like
cd04967691-771  Ig1_Contactin
cd05869704-772  Ig5_NCAM-1
cd05856617-689  Ig2_FGFRL1-like
pfam13927494-581  Ig_3
cd05762700-781  Ig8_MLCK
cd05730618-689  Ig3_NCAM-1_like
cd05734710-776  Ig7_DSCAM
cd05723618-689  Ig4_Neogenin
cd05731712-775  Ig3_L1-CAM_like
cd05744616-689  Ig_Myotilin_C_like
cd05736616-679  Ig2_Follistatin_like
cd05894605-689  Ig_C5_MyBP-C
cd05754696-779  Ig3_Perlecan_like
pfam13927599-676  Ig_3
cd05868707-781  Ig4_NrCAM
cd05852707-780  Ig5_Contactin-1
cd05892710-780  Ig_Myotilin_C
cd05764707-780  Ig_2
pfam1279971-110  LRR_4
cl1930271-110  LRR_4 superfamily
cd05739707-779  Ig3_RPTP_IIa_LAR_like
cd05876710-780  Ig3_L1-CAM
cd05733618-687  Ig6_L1-CAM_like
cd05868618-690  Ig4_NrCAM
cd05750712-778  Ig_Pro_neuregulin
cd04972605-689  Ig_TrkABC_d4
cd05733712-771  Ig6_L1-CAM_like
cd05757722-768  Ig2_IL1R_like
cd04976710-780  Ig2_VEGFR
cd05892616-689  Ig_Myotilin_C
cd05852618-689  Ig5_Contactin-1
cd05848599-687  Ig1_Contactin-5
pfam15369841-1013  KIAA1328
cl21207841-1013  KIAA1328 superfamily
cd05773711-778  Ig8_hNephrin_like
cd05722701-771  Ig1_Neogenin
cd05760618-691  Ig2_PTK7
cd04970618-693  Ig6_Contactin_like
cd05851618-679  Ig3_Contactin-1
cd04977704-772  Ig1_NCAM-1_like
cd05864710-781  Ig2_VEGFR-2
cd05850708-771  Ig1_Contactin-2
pfam00047615-674  ig
cd05857617-689  Ig2_FGFR
cd05870696-770  Ig5_NCAM-2
cd05876618-689  Ig3_L1-CAM
cd05867707-781  Ig4_L1-CAM_like
pfam12799211-251  LRR_4
cl19302211-251  LRR_4 superfamily
cd05724500-595  Ig2_Robo
pfam07686694-767  V-set
pfam13895494-595  Ig_2
cd05858707-781  Ig3_FGFR-2
cd05854616-693  Ig6_Contactin-2
cd05722498-595  Ig1_Neogenin
cd05848710-771  Ig1_Contactin-5
cd05723710-780  Ig4_Neogenin
pfam08205696-774  C2-set_2
cd05870605-679  Ig5_NCAM-2
cd05874618-684  Ig6_NrCAM
cd05732605-679  Ig5_NCAM-1_like
cd05743618-689  Ig_Perlecan_D2_like
cd07693495-595  Ig1_Robo
cd05869618-689  Ig5_NCAM-1
cd04967599-686  Ig1_Contactin
cd04969527-588  Ig5_Contactin_like
cd05754605-687  Ig3_Perlecan_like
cd05774704-780  Ig_CEACAM_D1
cd07702617-690  Ig2_VEGFR-1
cd04971717-774  Ig_TrKABC_d5
cd05740710-774  Ig_CEACAM_D4
pfam12799283-323  LRR_4
cd05756703-767  Ig1_IL1R_like
cd05749601-688  Ig2_Tyro3_like
cd05737605-689  Ig_Myomesin_like_C
cd05741724-780  Ig_CEACAM_D1_like
cd04979702-780  Ig_Semaphorin_C
cd05714707-767  Ig_CSPGs_LP
cd05863710-773  Ig2_VEGFR-3
cd05734618-689  Ig7_DSCAM
cd04972693-780  Ig_TrkABC_d4
pfam1279992-132  LRR_4
cd05760710-771  Ig2_PTK7
pfam07679599-689  I-set
pfam07679693-780  I-set
pfam13855211-271  LRR_8
pfam13855383-442  LRR_8
pfam07679495-595  I-set
pfam13855308-367  LRR_8
pfam1385571-127  LRR_8
pfam13855140-223  LRR_8
pfam13855259-319  LRR_8
smart00409700-780  IG
smart00410700-780  IG_like
smart00408707-770  IGc2
COG488667-328  LRR
COG488662-246  LRR
smart00409605-689  IG
smart00410605-689  IG_like
pfam13855236-295  LRR_8
PLN0011372-383  PLN00113
pfam13855340-394  LRR_8
PLN0011373-438  PLN00113
PLN0011362-442  PLN00113
COG4886198-396  LRR
PLN0011372-443  PLN00113
smart00408616-679  IGc2
pfam13855197-247  LRR_8
TIGR00864412-490  PCC
PRK1537062-252  PRK15370
pfam13855115-175  LRR_8
pfam13306341-439  LRR_5
smart00409501-595  IG
smart00410501-595  IG_like
PLN00113114-445  PLN00113
COG4886290-439  LRR
PHA02785573-763  PHA02785
smart00408509-584  IGc2
PRK1537051-178  PRK15370
PRK1538751-251  PRK15387
PHA02826724-765  PHA02826


Ontology Information


   
HPRD ID7670
Molecular ClassCell surface receptor
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO