Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| PRPF31 | 26121 | PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)  | 19 | RP11; PRP31; NY-BR-99  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20089989    | 2010 | Cell line : - Source : VU University Medical Center, Amsterdam, The Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : TNM Stage II | Biochemical isolation to nano-LC-MS/MS analysis | Unknown | - | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.[provided by RefSeq, Jan 2009]   |
| Chromosome | 19 |
| Location | 19q13.42 |
| Start | 54115376   |
| End | 54131719   |
| Strand | -   |
| Gene Sequence |    Download   Select all |
| Length | 16344   |
| OMIM ID | 606419    |
| HGNC ID | HGNC:15446    |
| Unigene ID | Hs.515598     |
| Ensembl ID | ENSG00000105618    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | NM_013342.3 |
|---|---|
| Exon | complement(<1..300)   | mRNA Sequence |    Download   Select all |
| Length | 2243   |
CDS Information
| Location | join(2904..3080,3198..3258,6485..6568,7122..7219, 8079..8185,8374..8543,9124..9281,11153..11242, 12698..12825,12930..13002,13682..13810,13897..13995, 15932..16057) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS12879.1 |    
Protein Information
| Protein ID | NP_056444.3 |
|---|---|
| Protein Name | PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) |
| Molecular Wt. (Da) | 55325 |
| Protein Sequence |    Download   Select all |
| Length | 499   |
| Uniprot ID | P05413 |    
| Ensembl Protein ID | ENSP00000362817   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 439 |
| T | Phosphorylation | 440 |
| S | Phosphorylation | 445 |
| T | Phosphorylation | 455 |
| S | Phosphorylation | 446 |
| T | Phosphorylation | 448 |
| S | Phosphorylation | 450 |
| S | Phosphorylation | 451 |
| S | Phosphorylation | 210 |
| S | Phosphorylation | 432 |
| S | Phosphorylation | 482 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Spliceosome |    hsa03040 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam01798 | 190-334  | Nop |
| cl03357 | 190-334  | Nop superfamily |
| pfam09785 | 336-465  | Prp31_C |
| cl10762 | 336-465  | Prp31_C superfamily |
| pfam08060 | 93-144  | NOSIC |
| cl06890 | 93-144  | NOSIC superfamily |
| smart00931 | 93-144  | NOSIC |
| COG1498 | 76-346  | SIK1 |
| PRK14552 | 92-346  | PRK14552 |
Ontology Information
| HPRD ID | 3490 |    
|---|---|
| Molecular Class | RNA binding protein |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
