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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
PRPF31 26121 PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)  19RP11; PRP31; NY-BR-99 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
20089989   2010Cell line : -

Source : VU University Medical Center, Amsterdam, The Netherlands.

Sample Type : CRC tumor and normal tissue

No. of Sample : -

Stage : TNM Stage II

Biochemical isolation to nano-LC-MS/MS analysis Unknown--


Gene Details



Chromosome: 19; NC_000019.9 (54618790..54635150)

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Gene Type protein coding
Gene Family -
Description This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.[provided by RefSeq, Jan 2009]  
Chromosome 19
Location 19q13.42
Start 54115376  
End 54131719  
Strand -  
Gene Sequence

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Length 16344  
OMIM ID 606419   
HGNC ID HGNC:15446   
Unigene ID Hs.515598    
Ensembl ID ENSG00000105618   
PharmGKB ID -   

mRNA Information


mRNA ID NM_013342.3
Exon complement(<1..300)  
mRNA Sequence

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Length 2243  



CDS Information


   
Locationjoin(2904..3080,3198..3258,6485..6568,7122..7219, 8079..8185,8374..8543,9124..9281,11153..11242, 12698..12825,12930..13002,13682..13810,13897..13995, 15932..16057)
CDS Sequence

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CCDS ID CCDS12879.1



Protein Information


      
Protein IDNP_056444.3
Protein NamePRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
Molecular Wt. (Da)55325
Protein Sequence

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Length 499  
Uniprot IDP05413
Ensembl Protein ID ENSP00000362817  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation439
TPhosphorylation440
SPhosphorylation445
TPhosphorylation455
SPhosphorylation446
TPhosphorylation448
SPhosphorylation450
SPhosphorylation451
SPhosphorylation210
SPhosphorylation432
SPhosphorylation482

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
Spliceosome hsa03040


Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam01798190-334  Nop
cl03357190-334  Nop superfamily
pfam09785336-465  Prp31_C
cl10762336-465  Prp31_C superfamily
pfam0806093-144  NOSIC
cl0689093-144  NOSIC superfamily
smart0093193-144  NOSIC
COG149876-346  SIK1
PRK1455292-346  PRK14552


Ontology Information


   
HPRD ID3490
Molecular ClassRNA binding protein
Molecular FunctionTranscription regulator activity (GO:0030528)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO