CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
GBP1	2633	Guanylate binding protein 1, interferon-inducible, 67kDa	1	-

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20454519	2010	Cell line : - Source : - Sample Type : - No. of Sample : 388 Stage : -	Proliferation Assay, Soft Agar Assay,Western Blotting and Immunohistochemistry	Unknown	-	GBPs might be considered as potent members in an innate, IFN-gamma-induced antitumoral defense system. GBP-1 has been shown to exert antiangiogenic activities and was described as a prognostic marker in colorectal carcinomas.
18697200	2008	Cell line : - Source : Department of Pathology of Wrocaw Medical University. Sample Type : - No. of Sample : - Stage : -	Immunohistochemistry	Up-regulation	-	GBP-1 was strongly expressed in endothelial cells and immune cells in the desmoplastic stroma of 32% of CRC .
22968445	2012	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	Laser capture microdissection,FFPE-FASP,SAX fractionation,LC-MSMS,Label-freequantitation.	Up-regulation	3	-

Gene Details

Chromosome: 1; NC_000001.10 (89517987..89531043, complement)
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Gene Type	protein coding
Gene Family	-
Description	Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008]
Chromosome	1
Location	1p22.2
Start	89052304
End	89065360
Strand	-
Gene Sequence	>gi\|568815597:c89065360-89052304 Homo sapiens chromosome 1, GRCh38.p2 Primary Assembly GGAGTCAGTGATTTGAACGAAGTACTTTCAGTTTCATATTACTCTAAATCCATTACAAATCTGCTTAGCT TCTAAATATTTCATCAATGAGGAAATCCCAGCCCTACAACTTCGGAACAGTGAAATATTAGTCCAGGGAT CCAGTGAGAGACACAGAAGTGCTAGAAGCCAGTGCTCGTGAACTAAGGAGAAAAAGAACAGGTAAGAACT TTTACTACTTCTCATCAAGCAGCTTTCTCTCTAGCTCCAAAGGATCTCAGCTCAGTGATATGGAACCTAT AAGGTTGTGGCAGGGATGGGAAGGAATTTATAAAGGTCAGTTCATTTTCTTAAACATCATCAGAACCAAA TTAGGCTGCAGATGAGCCTGAAGTGGGACGCAGGTCAGATGAAATCCTGGTGTTATCAGGGACAGCATGG CCTTAAGTGCCACTACAGTGCTTGTGTTGAATTAGGCACCAGTAGACAGGGGCTAAACTGAGCATTTGAA ATGTACTAGGATAGTCTTTCTCTTTGTTGACATTATCTATGTTGACTAGGGATATGATTACATTTCCATC GTCAGTGATGGACTGAATCCTGCTTCTATGCAGCTAAGAAATGGAAGAGTTACAAACGGGTTCTTTTCAT GGAAGGAAAGAACAGCAAATGAGAAGCAGAGTAAGCAGCCCACTGACACGGTTAAAGACAAAGAAAAAAC TGAAACTCAGCCTGAAAGATGAAGATTCATGAAAACAGTATACTTTTTATTACACTTGTGAACTTTGTTT CAGAATGGATTACTTTCTTTAGAAATAGTCCAGACTCACTAATTTCCTAGTGCCCACTGATCCCTGTCCC TTAGAAGTGAAATTCAACCCCACTGCTTCACTGAAGTGCTTCCAATTTTGTCTTCTTTTAGTAGAGAGCA GGGCCAAAAGTGTTTCCTCTTTAATTCTCCTGTAATGCATCTCTACAGAAAATATCTTTGCTTACTTTAA CCTCTCCATGCACTCAGACTACTTTGATCCTGCCTTCTGCAAAGTCTTCCCCTGAATGCCTTGTCAAGAC ACTAGCCTCATTCATCACCTCTGGTCTGACAGCTCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC ACACACACACACACACACACACACACACACACACACACACATTCCCAGCCCCTTATCCTCCTCTCCACTC CTACTATTCCTCCTCTTTCTATTTCTCTTTCTCCTACCCTACCAAATGGAAAACAGAACAAAACAGAAAT CCTAAAGCTGTATCGCTGGAAATATATTTTATTTGAACAACTTCCTAGGTAGCTCTCTTTATCTGCCTCT TGATCTTTTAATCCTTATTATCTGGAGGAAACATTCAGTATTTGCAATTTTGCATTCATACCCTCAGTGA CTTAGAAGCTATCTTATCGTGACTCTAATGAAGCTTAAGTTTCAGGGCCCTTCTCTTGGACATGACCCTT AGGAGCCCTTGGAAGGTTCCCTAGCCATGTGTTTCACATGGTTGTATAGTTTTATAAAATTTGCAAAAGT ATGTTACATTGTTACCACTTCCAGAATGGCAATGTGAGAAGCTTTGTCAATCCTCATTGCAGTGAAATAA GCATAATCATTTGAAGATGGAGGAAGGAACACATTTAAAAATCTTTGGAAATTTTTCTAAGGGTAAACAT CAAACTATGAATACTGATTCACTGTGTTGGATGTTTATTCACTGTGAGAATTAATAAGTGAATCAATATT GAATTCCTTACATACAGCCAGGATGCAAATAAATCCTCTAAATCCTATTCTATCTTCCATTAATTGACTA GTGAAAATATCTAATAAGAATCCAAAAAGAAAGTTTTCCACAATAAACTAAATGAAATATTTGGGTCGTG AGAGTAGTTGAGTGTTGATAAGTCACTGTCATGCTAACATTTTTCATAATGAGCTACTTTGACAATACTT CCATAACTTTCTCAAATGATACAGATTTTGCCTCATCTCTTTTGCTGTCACACACAAAACTTTTGGCCAT ACTGGGGAATCTTATGATTCTCCCTTATAATTGCAAAACACTAGAAATTCTCATGTATTTCACCTCTTCT CTTGCAGACAAGGGAACAGCCTGGACATGGCATCAGAGATCCACATGACAGGCCCAATGTGCCTCATTGA GAACACTAATGGGCGACTGATGGCGAATCCAGAAGCTCTGAAGATCCTTTCTGCCATTACACAGCCTATG GTGGTGGTGGCAATTGTGGGCCTCTACCGCACAGGCAAATCCTACCTGATGAACAAGCTGGCTGGAAAGA AAAAGGGTGAGTGGCATGAGCAAAGCTCTGCCAAGTCCCTTCTGTCCATCTACACAGTCAGCCTCCATTA TGAAGATGTGAGGAGAGAAAGAGATGAGGATGAATACTGAAAGCTAACTTTCCATTCACAGTCGGGCTCC TTATCTTCACGCTGTTCTAGGGGATAAGAATCAATTCATTAATTATTCCCATGATACCTTAGTTTCCATT TCAAAAGCACAAATTATGCCTCTCCTAAAAGGAGTAAGACAGTAATAAAAATAATTAATGTACATAATAA TAACTATAATAAACTATACAATGTTTATTACAATTTTTATGCAATAACAGAGTTCACAGTGATCTTTAAG GTTGAAAAAATGTTTCAATCTGTAGTGGATATTATTTTTTGTTGTTGTAAAAAAAATAAAATTTAACCTC GTAACCATTTTTAAGTGTACAGCTCTGTAGCATTAATGAAATTCACATTGTTATACAGCTGTCACCTCCA TCCATATCCAGAAATCTTTCATCTTGCCTAACAGAAACTGTATTAACTAAACAAAAGCTCCACATAAACC CATTGCCTGCCATCATTCTACATTCTATCTCTATGAATTTGACTACTACAGAAACCTTATATAAGTGGAA TCATTCAATATTTGTCCTTTTATGACTGGCTTATTTCAATTCATATGTCTTCAAGGTTCATCAGTGTGTT AGCATGTGTCAAAACTCTTCCTTTTTAAGGCTTAGTAATTGTACGTGTATACTAATTTGTTTATCTCTTC ATCTGTCAATGGACACTTGGATTTCTTCCACCTTTTGTCTATTATAAATAATGCTAATAGGAACATGGGT GTCTGAATATCTGTTCAAGTCCCTGCTTTCACTTCTTTTGGGAATATACCCAGAAGGGGAATTGCTGGCT CATGCAGTCATTGCATGTTAACTTTTTTTAAGAAATCACTATACCATTTTCCACAGTGACTGTACCGTTT TACATTCTCAACAGAAATGCACAAGGGTTCTAATTTCTCTACATCCTCACCAACATTTTTTATTTTCAGT GGTTTTTTTTTTTTATAGTGGCCATACGAATGGAAGTTAAGTAGTATCTCGTTGTGGTTTTGATTTTGAT TTCCGTAATGACTAGTGATGTTGAGCATCTTTTCACGTGCTTATTGGCCACTTGTATATCTTCTTTGGGA GAATGTCTATTCAAGTCCATTGTTCATTTATTAATCTGGTTGTTTATTTCTGTTGCTTTGTAAATTTTTT TATATTTTCTAGATATCAATCCCTTATCATATACATGTTTAGAAACCATTTTCTTACATTCCGTGTGTTG CCTTTTTTAACTCTGTTGATAGTGTCCGTTAATACACAAAAGTTTTAAATTTTGCTGAAGTCCCACTAAT CTATTTTTTCTTTTATTGTCTATAGTTTTGGTTTCTTATTCAAAAAATAATTTCCAAATCCAATATTATA AAACTTTTACCCTTTATTTTCTTCTACAACTTTTATAGTTTCAACTCTAATGTTTGGTTCTTTGATCCAT TTTGAGTTCATATTTGTAAGTTATAAGGTAATAGCCCAACTTTTTAAGGAGATATATCATTTCCTCAACA TCATTTGTTAAAGAGACTCTCCTTTCTTCATTAAATGATCTTGACACCCATACTGGAAATCATTTGACCA TATATATCAGAGTTTATTCATGGGCTGTCTTTTCTATTCTATTGGTTTATATGTCAGTCTTTATACCAGT ACCACACATGGTTTTGTAATACGTTTCACAACTCAGAAACTGTGAGACTCCAACTTTGCTCTTCCTTTTT ATTTTTATAATTAGGGGATCTCTGGAAATTTCATATGAAATTTATGGTGGATTTTTCTATTTATACAAAG TAATTGGAATGTTGGTAGGGATTATATCAAACCTGTACATCACTTTGGGTAGTAGTGACATCTTAAGAAT ATTAAGTCTTCCAATCCATAAACACAGGATGTCTTTCTAATAACTTATGTCATCTATAATTTCTTTAAAG GGTGTTTGAAGTTTTCACTCTACAAGTCTTCCACCTGCTTGGTTAAGCTGATTCCTAAGTAGTTTATTCT TTTGATGCTGTTAAATTGGATTGTTTCCAAAATTTCCTTTTCTATTTTTTACACTAGCAACTGATTTCTC CATATTGACTTTGCATGCTGCAACTTTGATGAATTGTTTTAATAGTTCTAATAGTTTTTTGTGGGATAGT TAATGTTTTCTACAAATTAGATACTATCATCAGCAGACAGAGATAATTTTACTTTTTCATTACCAATTAG GATGCCTCCTTTATGCTTCTCTTGTCTAATTACTCTGGATAGGACTTGCAGTGTTCTGTGGAATGCAATT GACAAAAGTAGGCATCCTTTTCTTGTTCATGATGTTATAGGAAAAGCTATGACGTTTCATCATTAAATGT GAAGTTAGCTGTGGGTTTTTAATACATGGCATTTATTATGTTGAGGTGCTGTCTTTCTATTTCTACTTTG TTGATTATTTTTATCATGAAAGCCTCCTGAATGTTTCCATGCATTGGATATTCAAATTTCCTATTTCTTT GATTGTAAGTACGTAAGGTGAATACTGATTGTTGTTTCAGTTCTCTCTCTTAACCTTAAATATACTACTT TTTCCTTCAATTGCCAGAACTGCCTGTTACTAAATCCCCATCGCTGGTCTCCTCTCTCCCTTGCAGGCTT CTCTCTGGGCTCCACGGTGCAGTCTCACACTAAAGGAATCTGGATGTGGTGTGTGCCCCACCCCAAGAAG CCAGGCCACATCCTAGTTCTGCTGGACACCGAGGGTCTGGGAGATGTAGAGAAGGTGAGACTCAAGGATC CAGTTGTGGAGTAAGCCCCTCCTCTCTGAATATTTTATGCAGCGGTTAATTGTTTATTAACTATTAACTA CAGGCTGTAATATGTGTGGGTTAACACAGATGCATAAAGGGAGCACAAATAATCCCAGTGTCATAAGTCT TATCCTGCACAGAACTTTAGTTAAGAATTTGGGTGCTAAAGCCATGTGACTTTGTATTTAAATTTAAATT CTGTCACTAATTCAGTAGCCTGAGAAAATTGACTTATTTTCGCCTCAGCATTCTAATCTTTAAAATGTAT GGAAAAGACCTATGTTGGCCATATAGTATTATTTTGAATATTTAATAAGATAATACATTACAGGTGTATA TTAATTATTCAATAAAATAGCAACTAATAGTACCAATCTTATATGTGAATTCTGTTATTGAAAAAAAGAA GAGAAAATTTTAAATTTACATTGTACTCAGGCCTTAAAATGCCCACCAACCTTGAATTTTAATTTTACAA TTATCTGTTGATGATCATTAGAAGACCTAGTAAGAATCATGGTAACCCAAAAACACTCGTCGAAAAACTA CCCAAAAGCCACATCCTACTGAGAATAATTTTTGTATTTGTCTTCCTTTAATAGGTCATTAGTGTTAAAA AAAAAAAAAAAAAAGAAAAGAAAAAAAAACCCTCTAACATATGAACATAGTTTTACTACTGTTACTCTGA AAAGTGCTGCGATGATGAAACTTGCTCCTGACTCCAGTGTGTCTTGACTTCCAGGGTGACAACCAGAATG ACTCCTGGATCTTCGCCCTGGCCGTCCTCCTGAGCAGCACCTTCGTGTACAATAGCATAGGAACCATCAA CCAGCAGGCTATGGACCAACTGTAGTATCCTTTTGTGACCCAGAACAGCACCAAGGTCAGAGGGGACACC TGTATTCATACACCAGCTGCCTGACTGTGAATCCTGATGAATCAAGCTCAAAAGGAGAAAACAAAAAATA ATGCAAGTACAGAGGAGAGATCCCATGTATCCACTTTAGAACTGACACTGACACTTAGGTTAGGAGCAAA GGAAAATGGAAGGTTTGGGTATGTGTTGAACTAACATGGGATGAGGTCCCTGTTCATTTTGTCACATTTC CTTAGTTAGCTACTCAGCTATGTGACAGAGCTGACACATAGAATCCGATCAAAATCCTCACCTGATGAGA ATGAGAATGAGGTTGAGGATTCAGCTGACTTTGTGAGCTTCTTCCCAGACTTTGTGTGGACACTGAGAGA TTTCTCCCTGGACTTGGAAGCAGATGGACAACCCCTCACACCAGATGAGTACCTGACATACTCCCTGAAG CTGAAGAAAGGTAACAGAGAGCTTCAACTGATAAATGAGGATGAGAAAACACAAGAAATTATCATTTTTC AGTTTACTATTGCTAGTTTTCCAGCATTTGCAGTTTTCTATGTCTTCAGCTGGCTATTCCTAGAAATTAA TACTTGCTGAATATCCAAATTAATAGATGTTATTTTAAATTACATTTGTCATTGTTCTAGAACAAGTTTC TTGTTCTTTCACCTTTGTGTATGCTGTGATTAGGTTAATTTTATCTCCCTGCCTAGGGTTTGTGATCTTC TACTTAGCCATAGAGTATGGAGTACAATGGATATTTATTTAAAGAACATAGACTAAAACATGAACCGTGT GCTAGTCCAAGCATTGGCAAACTACAGCCCAAGACAAATCATGGCAAATCCTGCCTGCCAGCTGTCTTTG TAAATAAGGTTTTTTTGGAATAATGCTATGCCCATTCATTTACATATTGTCTAAAGCTGTTGTCATGCTT CAATAACAGAGTTGAATACTTGGAAAAGAGACCATCCAGCCTGAAGAGCCTAAAATATTTACTATTTGGC CCTTTACAGAAACACTTATATTAGGCAATTTTATAATTTTTTAAATGTTTTTCTAGGTACCAGTCAAAAA GATGAAACTTTTAACCTGCCCAGACTCTGTATCCGGAAATTCTTCCCAAAGAAAAAATGCTTTGTCTTTG ATCGGCCCGTTCACCGCAGGAAGCTTGCCCAGCTCGAGAAACTACAAGATGAAGAGCTGGACCCCGAATT TGTGCAACAAGTAGCAGACTTCTGTTCCTACATCTTTAGTAATTCCAAAACTAAAACTCTTTCAGGAGGC ATCCAGGTCAACGGGCCTCGTAAGTCCCCTTCCTAGTACTTCTGCTCATTGTTTAAGACTAGAGGAGCAT AGAATAACTTCCACCTAGTTTCAGCATTGAAAAATCCCAATCTACTGCTATATTTGTGTTAAATTCTAGA TGGCACCAATGTTTCTAACATATATTGTTAGTCACATTTCCAGTCTAGGAAAAGGCCAAAGGAAAAAAGT TCTATTGCTTGAAATTGCCCTAGTGAACTGGACCTGCACTATGCAATAGAGTAGCCCCTAGACAAGTGTG TCTATGTAAACATAAATGTAAATAATTTAAATAGGGAAAATTTAAAAGTCAATTCACATGCCTGTATTTC AAGGACTAATATTTACACGTACTTAGTGACTAGCACACTGAAAAGCACATATACAACATTCCCAGCATTA CAGAAAGCGCTTTTGAACAATACTGCAATAAAATAAACTAAATGGATGACTCTTTTTTATTGGAATAGTG TCATTTGTTTCATACATATTGATCAAATGCTTACTATGAATAGACTGAAGATACAGATATAAATGAAATA GATATGGTTCCTGTCCTAATGTTGGTTGGGGTTAAAATGGATGCAAACATTCAATTAACACAAGTCTATG TAATCTAGTACAAGAACTCTCAAATGTTGGTATGCATACATATCTTCTGAGGATCTTACCAAACACAAAA GTCTAATTCAATAGATCTCGGACAGGGTCTGAGAGTCTATTTCCAGCAAGCTTCCAAGTGATGCTGAGGA CATTGATGCTGTGAGGAAAATAGGTGGTATTTGACATGCTCAGAATTACATGGAATAGAGACTTTCTTTA CCACCAGAAACATTATCATTTGTTCTTCATATGCAGGTCTAGAGAGCCTGGTGCTGACCTACGTCAATGC CATCAGCAGTGGGGATCTGCCGTGCATGGAGAACGCAGTCCTGGCCTTGGCCCAGATAGAGAACTCAGCT GCAGTGCAAAAGGCTATTGCCCACTATGAACAGCAGATGGGCCAGAAGGTGCAGCTGCCCACAGAAACCC TCCAGGAGCTGCTGGACCTGCACAGGGACAGTGAGAGAGAGGCCATTGAAGTCTTCATCAGGAGTTCCTT CAAAGATGTGGACCATCTATTTCAAAAGGAGTTAGCGGTAATTTTTGTCTCAAATGTATACGGTTTAGGG TCATAGAAGCTAAAGTACCACAAGGAAAGAAAACTATTATTTATTTTGACGGAAGTAATTCCTCCTAGCT TCCATAATGGTGAAAACAACAGATTTGTGATCACATCAGTCAGAAGGACCAACTGTATTATTACAGACCC AAAGTTCTAAAACATTTTTTCCTGAATAATTTTCCCTTTACTTATGCATACAACTGACAACCAGAGCTTC TAATAAAATTACCTGCCCACTCTTCTCAGACTGATTTGATATTCTAGCCAAACACAAAGAAAATTTTCAT CCTACTTATCTTGAGCAGGCTTCCGTTCAGCCACATTTATTCCATATGAAATCATTAGTCCAATATGCAA AAACAGAGTTTTCCTCTAACAGTTGACATAAAGCTATCAATCTCAGCCCTGAACCTCACCTCCAAAAAGA AAGCGACTTCAGCAGAAAGTGGGGTCAGAAGGAAGAGTGTGGTCCTGGTGAGGAGGCTGTCAGTTTCTCC AGCATCATTGACTTCTATTTTCAGAAATCGTTCCCAAAATTCTGAGGTCAAGCTAACATCCTTTCCCTGT TACTCTTTTTACTTCCTATTTTTACATTAAAGGCCCAGCTAGAAAAAAAGCGGGATGACTTTTGTAAACA GAATCAGGAAGCATCATCAGATCGTTGCTCAGCTTTACTTCAGGTCATTTTCAGTCCTCTAGAAGAAGAA GTGAAGGCGGGAATTTATTCGAAACCAGGGGGCTATCGTCTCTTTGTTCAGAAGCTACAAGACCTGAAGA AAAAGTACTATGAGGAACCGAGGAAGGGGATACAGGTAACCAAGATTTATCTGTCAATTATGGAAAGCTG CTGACCTGCCTCCTACAAACACCAAGGTGACCAAGCTTCACTGCATACAGATGTGCTTTTTTGTTTGCAT AACATTCATGCTTTTATTCAATAACATATGCAAACAGGCTGTTATACCAGATATGTCCTAGGTGCTCATC AAAGAGAGTGCAGTCAATTAACTATTAAGTTATAAATTCAATTAGCAGATGAAGCACAAAGTTATTATTG TCATCATTACAGCTGGGCTTTTCCTGTTGCAAGAGACAGGAACCCAATGATGGCTGCTTAAACAAAAATG TAATTCATTGATTTAGGCTGCAAACTGGCTTTACAGGTCAGGTGGGTCTAAGGTTTCAAGTAACATCATG AACTGGCTCTCTGTCCAGTGTTCCCCCATCCCCACAGTTTTCTCCCTCCCACCATCCCTCTATCTGAGTC ACTCTGATATTTGCTTTCTCAATGATGGCTTCATTCCCCAGCAGGCTCAGCCCATATGGGACCACAGCAT TAACAGTTCCAAACTTAGAGCCCTTAATCTAAACAGGACAGAGACTCTCCTTTTCCCAGTATCTATATTA GCCTACTAAAAATGACTGCTAAGTAGGATGTTCTGATCGGCTTGCCAGGAGCATGTGTCTGTCGCTCCGA CAGGGAATTTGACCACCAAGGACAATAGGGCCAAGAGAAAGAATTCCCAGAGGAGAAAGGATGGCAGGAA GACAAACAGGAACACCTGCTTACAGCCATTTCCTACTTCTCACTCTGTGTTCTCTGGGTCCTAAGGCTGA AGAGATTCTGCAGACATACTTGAAATCCAAGGAGTCTATGACTGATGCAATTCTCCAGACAGACCAGACT CTCACAGAAAAAGAAAAGGAGATTGAAGGTGAGGAGTGAGTTAAGAGATTAGATGGCCTCAAAAGCTCCA AAAATTGAAATAACTTGACTGGATAAACATGGGACCCTTTAACTAGAGCAAGATCCACAAAGGTGTGTCT TACTTGCCGAGGTCATCTCTGAGTAGGGCATATGCAGTCAGCAACAACGACAGGTAAGTGTATAAGGAAG AATGAGGCAACAAGATAACCCCACACAAATTTTTCTTCTGCCTTTTCCTCCTCAGTGGAACGTGTGAAAG CTGAGTCTGCACAGGCTTCAGCAAAAATGTTGCAGGAAATGCAAAGAAAGAATGAGCAGATGATGGAACA GAAGGAGAGGAGTTATCAGGAACACTTGAAACAACTGACTGAGAAGATGGAGAACGACAGGGTCCAGTTG CTGAAAGAGCAAGAGAGGACCCTCGCTCTTAAACTTCAGGTATCTAATTGCATCACCTTGAGGTTTCTGT TTTTCTGTTTTCTCTCCATTCTCCCTGATCGCAAACTTAGTGTGGCAGAGAGAACATGAAGCCCAGGGTA AGGACCCTGCTTGCTTACTTGTACTTTTCAATTCCTGTCTGTCCAGCCTGACTGGCTACTGCCAAGTCTG GTCACTGAAAGTTTTTTATTTGCAGTTGTGTAACATTCAGTCCTTTATCAATATATCCTTCATTTCAAGG AAGCTATTATCTGCTAGGCATCATTAAAATATCTGTATCTCGGTGGGGCATTGTGGCTCACGCCTGTAAT CCCAGCACTCTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGGAGATTGAGGCCATCCTGGCTAACACG GTGAAATCCCGTCACTACTAAAAATACAAAAAATTTAGCTAGATGTGGTGGCGGGCACCTGTAGTCCCAG CTACTCAGGAAGCTGAGGCAGGAGAATGGAGTGAACCCAGGAGGCAGAGCTTGCAGTGAGCTGAGATCGC ACCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCAAAAAAAAAAATCTGTATCTCTTGCTTAATAA CATATGTAGCAAGAACTATATCCTTATTACTTAGAAGAAGAAACAAAGGTTCCAAAAAGAATAAATAATT AAGTTCACACAGCTAGTAAATATATCAGAGCTGTCTTCATCACTTAGCGGAATCCACAATGATTATTTGT TTCTGTGACACCTACTATGAAATTAGATTTAAGAAACCTTTATGAGCAGAAAGGCTCCTAACCCTCACAC CTGTGTGATACTCTGCTAATTCTGATTATTTTTAATGTCCTGCTCCCAGTTTGTTTTGAGTTGTGAGCTA TGTGCAGAAACTCAGTATGGTCAGTCTGGCACTCAGATTTCTTACCTGTCTTCTGCTACCCCTGACACCA AGGTGTGGCAGCTTAGACCAAATTTCCTAATCCATGATTCATACACCTTATGAGATTTTGAGGATACTTT GCTTATTTCGGTGTTATGTCATATACATAATAGGGTAAGGAACATGGCTGTGCTTTGGTCAATGATAGGC CAAAGTATGACATTTACGTCTTGCGTGACTCAGAGAAAATTAAATAACAAATCATTTAATGTGGAAACCA GATAGAATGTTTCAATTTGCCTGATGCTACACTTTACTCAGCCTTCGTTTGTCCCTTTTTAGGAACAGGA GCAACTACTAAAAGAGGGATTTCAAAAAGAAAGCAGAATAATGAAAAATGAGATACAGGATCTCCAGACG AAAATGAGACGACGAAAGGCATGTACCATAAGCTAAAGACCAGAGCCTTCCTGTCACCCCTAACCAAGGC ATAATTGAAACAATTTTAGAATTTGGAACAAGCGTCACTACATTTGATAATAATTAGATCTTGCATCATA ACACCAAAAGTTTATAAAGGCATGTGGTACAATGATCAAAATCATGTTTTTTCTTAAAAAAAAAAAAAGA CTGTAAATTGTGCAACAAAGATGCATTTACCTCTGTATCAACTCAGGAAATCTCATAAGCTGGTACCACT CAGGAGAAGTTTATTCTTCCAGATGACCAGCAGTAGACAAATGGATACTGAGCAGAGTCTTAGGTAAAAG TCTTGGGAAATATTTGGGCATTGGTCTGGCCAAGTCTACAATGTCCCAATATCAAGGACAACCACCCTAG CTTCTTAGTGAAGACAATGTACAGTTATCCGTTAGATCAAGACTACACGGTCTATGAGCAATAATGTGAT TTCTGGACATTGCCCATGTATAATCCTCACTGATGATTTCAAGCTAAAGCAAACCACCTTATACAGAGAT CTAGAATCTCTTTATGTTCTCCAGAGGAAGGTGGAAGAAACCATGGGCAGGAGTAGGAATTGAGTGATAA ACAATTGGGCTAATGAAGAAAACTTCTCTTATTGTTCAGTTCATCCAGATTATAACTTCAATGGGACACT TTAGACCATTAGACAATTGACACTGGATTAAACAAATTCACATAATGCCAAATACACAATGTATTTATAG CAACGTATAATTTGCAAAGATGGACTTTAAAAGATGCTGTGTAACTAAACTGAAATAATTCAATTACTTA TTATTTAGAATGTTAAAGCTTATGATAGTCTTTTCTAACTCTTAACACTCATACTTGAAAACTTTCTGAG TTTCCCCAGAAGAGAATATGGGATTTTTTTTGACATTTTTGACTCATTTAATAATGCTCTTGTGTTTACC TAGTATATGTAGACTTTGTCTTATGTGTGAAAAGTCCTAGGAAAGTGGTTGATGTTTCTTATAGCAATTA AAAATTATTTTTGAACTGAAAATACAATGTATTTCAC Download Select all
Length	13057
OMIM ID	600411
HGNC ID	HGNC:4182
Unigene ID	Hs.62661
Ensembl ID	ENSG00000117228
PharmGKB ID	-

mRNA Information

mRNA ID	NM_002053.2
Exon	join(1..201,2108..2316,5037..5164,5935..6044,6318..6520, 7127..7369,8227..8507,9133..9345,10146..10248, 10486..10679,11893..13057)
mRNA Sequence	>2633 GGAGTCAGTGATTTGAACGAAGTACTTTCAGTTTCATATTACTCTAAATCCATTACAAATCTGC TTAGCTTCTAAATATTTCATCAATGAGGAAATCCCAGCCCTACAACTTCGGAACAGTGAAATAT TAGTCCAGGGATCCAGTGAGAGACACAGAAGTGCTAGAAGCCAGTGCTCGTGAACTAAGGAGAA AAAGAACAGACAAGGGAACAGCCTGGACATGGCATCAGAGATCCACATGACAGGCCCAATGTGC CTCATTGAGAACACTAATGGGCGACTGATGGCGAATCCAGAAGCTCTGAAGATCCTTTCTGCCA TTACACAGCCTATGGTGGTGGTGGCAATTGTGGGCCTCTACCGCACAGGCAAATCCTACCTGAT GAACAAGCTGGCTGGAAAGAAAAAGGGCTTCTCTCTGGGCTCCACGGTGCAGTCTCACACTAAA GGAATCTGGATGTGGTGTGTGCCCCACCCCAAGAAGCCAGGCCACATCCTAGTTCTGCTGGACA CCGAGGGTCTGGGAGATGTAGAGAAGGGTGACAACCAGAATGACTCCTGGATCTTCGCCCTGGC CGTCCTCCTGAGCAGCACCTTCGTGTACAATAGCATAGGAACCATCAACCAGCAGGCTATGGAC CAACTGTACTATGTGACAGAGCTGACACATAGAATCCGATCAAAATCCTCACCTGATGAGAATG AGAATGAGGTTGAGGATTCAGCTGACTTTGTGAGCTTCTTCCCAGACTTTGTGTGGACACTGAG AGATTTCTCCCTGGACTTGGAAGCAGATGGACAACCCCTCACACCAGATGAGTACCTGACATAC TCCCTGAAGCTGAAGAAAGGTACCAGTCAAAAAGATGAAACTTTTAACCTGCCCAGACTCTGTA TCCGGAAATTCTTCCCAAAGAAAAAATGCTTTGTCTTTGATCGGCCCGTTCACCGCAGGAAGCT TGCCCAGCTCGAGAAACTACAAGATGAAGAGCTGGACCCCGAATTTGTGCAACAAGTAGCAGAC TTCTGTTCCTACATCTTTAGTAATTCCAAAACTAAAACTCTTTCAGGAGGCATCCAGGTCAACG GGCCTCGTCTAGAGAGCCTGGTGCTGACCTACGTCAATGCCATCAGCAGTGGGGATCTGCCGTG CATGGAGAACGCAGTCCTGGCCTTGGCCCAGATAGAGAACTCAGCTGCAGTGCAAAAGGCTATT GCCCACTATGAACAGCAGATGGGCCAGAAGGTGCAGCTGCCCACAGAAACCCTCCAGGAGCTGC TGGACCTGCACAGGGACAGTGAGAGAGAGGCCATTGAAGTCTTCATCAGGAGTTCCTTCAAAGA TGTGGACCATCTATTTCAAAAGGAGTTAGCGGCCCAGCTAGAAAAAAAGCGGGATGACTTTTGT AAACAGAATCAGGAAGCATCATCAGATCGTTGCTCAGCTTTACTTCAGGTCATTTTCAGTCCTC TAGAAGAAGAAGTGAAGGCGGGAATTTATTCGAAACCAGGGGGCTATCGTCTCTTTGTTCAGAA GCTACAAGACCTGAAGAAAAAGTACTATGAGGAACCGAGGAAGGGGATACAGGCTGAAGAGATT CTGCAGACATACTTGAAATCCAAGGAGTCTATGACTGATGCAATTCTCCAGACAGACCAGACTC TCACAGAAAAAGAAAAGGAGATTGAAGTGGAACGTGTGAAAGCTGAGTCTGCACAGGCTTCAGC AAAAATGTTGCAGGAAATGCAAAGAAAGAATGAGCAGATGATGGAACAGAAGGAGAGGAGTTAT CAGGAACACTTGAAACAACTGACTGAGAAGATGGAGAACGACAGGGTCCAGTTGCTGAAAGAGC AAGAGAGGACCCTCGCTCTTAAACTTCAGGAACAGGAGCAACTACTAAAAGAGGGATTTCAAAA AGAAAGCAGAATAATGAAAAATGAGATACAGGATCTCCAGACGAAAATGAGACGACGAAAGGCA TGTACCATAAGCTAAAGACCAGAGCCTTCCTGTCACCCCTAACCAAGGCATAATTGAAACAATT TTAGAATTTGGAACAAGCGTCACTACATTTGATAATAATTAGATCTTGCATCATAACACCAAAA GTTTATAAAGGCATGTGGTACAATGATCAAAATCATGTTTTTTCTTAAAAAAAAAAAAAGACTG TAAATTGTGCAACAAAGATGCATTTACCTCTGTATCAACTCAGGAAATCTCATAAGCTGGTACC ACTCAGGAGAAGTTTATTCTTCCAGATGACCAGCAGTAGACAAATGGATACTGAGCAGAGTCTT AGGTAAAAGTCTTGGGAAATATTTGGGCATTGGTCTGGCCAAGTCTACAATGTCCCAATATCAA GGACAACCACCCTAGCTTCTTAGTGAAGACAATGTACAGTTATCCGTTAGATCAAGACTACACG GTCTATGAGCAATAATGTGATTTCTGGACATTGCCCATGTATAATCCTCACTGATGATTTCAAG CTAAAGCAAACCACCTTATACAGAGATCTAGAATCTCTTTATGTTCTCCAGAGGAAGGTGGAAG AAACCATGGGCAGGAGTAGGAATTGAGTGATAAACAATTGGGCTAATGAAGAAAACTTCTCTTA TTGTTCAGTTCATCCAGATTATAACTTCAATGGGACACTTTAGACCATTAGACAATTGACACTG GATTAAACAAATTCACATAATGCCAAATACACAATGTATTTATAGCAACGTATAATTTGCAAAG ATGGACTTTAAAAGATGCTGTGTAACTAAACTGAAATAATTCAATTACTTATTATTTAGAATGT TAAAGCTTATGATAGTCTTTTCTAACTCTTAACACTCATACTTGAAAACTTTCTGAGTTTCCCC AGAAGAGAATATGGGATTTTTTTTGACATTTTTGACTCATTTAATAATGCTCTTGTGTTTACCT AGTATATGTAGACTTTGTCTTATGTGTGAAAAGTCCTAGGAAAGTGGTTGATGTTTCTTATAGC AATTAAAAATTATTTTTGAACTGAAAATACAATGTATTTCAC Download Select all
Length	3050

CDS Information

Location	join(2127..2316,5037..5164,5935..6044,6318..6520, 7127..7369,8227..8507,9133..9345,10146..10248, 10486..10679,11893..12006)
CDS Sequence	>gi\|166706902:221-1999 Homo sapiens guanylate binding protein 1, interferon-inducible (GBP1), mRNA ATGGCATCAGAGATCCACATGACAGGCCCAATGTGCCTCATTGAGAACACTAATGGGCGACTGATGGCGA ATCCAGAAGCTCTGAAGATCCTTTCTGCCATTACACAGCCTATGGTGGTGGTGGCAATTGTGGGCCTCTA CCGCACAGGCAAATCCTACCTGATGAACAAGCTGGCTGGAAAGAAAAAGGGCTTCTCTCTGGGCTCCACG GTGCAGTCTCACACTAAAGGAATCTGGATGTGGTGTGTGCCCCACCCCAAGAAGCCAGGCCACATCCTAG TTCTGCTGGACACCGAGGGTCTGGGAGATGTAGAGAAGGGTGACAACCAGAATGACTCCTGGATCTTCGC CCTGGCCGTCCTCCTGAGCAGCACCTTCGTGTACAATAGCATAGGAACCATCAACCAGCAGGCTATGGAC CAACTGTACTATGTGACAGAGCTGACACATAGAATCCGATCAAAATCCTCACCTGATGAGAATGAGAATG AGGTTGAGGATTCAGCTGACTTTGTGAGCTTCTTCCCAGACTTTGTGTGGACACTGAGAGATTTCTCCCT GGACTTGGAAGCAGATGGACAACCCCTCACACCAGATGAGTACCTGACATACTCCCTGAAGCTGAAGAAA GGTACCAGTCAAAAAGATGAAACTTTTAACCTGCCCAGACTCTGTATCCGGAAATTCTTCCCAAAGAAAA AATGCTTTGTCTTTGATCGGCCCGTTCACCGCAGGAAGCTTGCCCAGCTCGAGAAACTACAAGATGAAGA GCTGGACCCCGAATTTGTGCAACAAGTAGCAGACTTCTGTTCCTACATCTTTAGTAATTCCAAAACTAAA ACTCTTTCAGGAGGCATCCAGGTCAACGGGCCTCGTCTAGAGAGCCTGGTGCTGACCTACGTCAATGCCA TCAGCAGTGGGGATCTGCCGTGCATGGAGAACGCAGTCCTGGCCTTGGCCCAGATAGAGAACTCAGCTGC AGTGCAAAAGGCTATTGCCCACTATGAACAGCAGATGGGCCAGAAGGTGCAGCTGCCCACAGAAACCCTC CAGGAGCTGCTGGACCTGCACAGGGACAGTGAGAGAGAGGCCATTGAAGTCTTCATCAGGAGTTCCTTCA AAGATGTGGACCATCTATTTCAAAAGGAGTTAGCGGCCCAGCTAGAAAAAAAGCGGGATGACTTTTGTAA ACAGAATCAGGAAGCATCATCAGATCGTTGCTCAGCTTTACTTCAGGTCATTTTCAGTCCTCTAGAAGAA GAAGTGAAGGCGGGAATTTATTCGAAACCAGGGGGCTATCGTCTCTTTGTTCAGAAGCTACAAGACCTGA AGAAAAAGTACTATGAGGAACCGAGGAAGGGGATACAGGCTGAAGAGATTCTGCAGACATACTTGAAATC CAAGGAGTCTATGACTGATGCAATTCTCCAGACAGACCAGACTCTCACAGAAAAAGAAAAGGAGATTGAA GTGGAACGTGTGAAAGCTGAGTCTGCACAGGCTTCAGCAAAAATGTTGCAGGAAATGCAAAGAAAGAATG AGCAGATGATGGAACAGAAGGAGAGGAGTTATCAGGAACACTTGAAACAACTGACTGAGAAGATGGAGAA CGACAGGGTCCAGTTGCTGAAAGAGCAAGAGAGGACCCTCGCTCTTAAACTTCAGGAACAGGAGCAACTA CTAAAAGAGGGATTTCAAAAAGAAAGCAGAATAATGAAAAATGAGATACAGGATCTCCAGACGAAAATGA GACGACGAAAGGCATGTACCATAAGCTAA Download Select all
CCDS ID	CCDS718.1

Protein Information

Protein ID	NP_002044.2
Protein Name	Guanylate binding protein 1, interferon-inducible, 67kDa
Molecular Wt. (Da)	67800
Protein Sequence	>2633 MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAGKKKG FSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVY NSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEAD GQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDE ELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALA QIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKEL AAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYY EEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRK NEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEI QDLQTKMRRRKACTIS Download Select all
Length	592
Uniprot ID	O00238
Ensembl Protein ID	ENSP00000264568

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
C	Prenylation	589

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

No matching records from HPRD source could be found.

Pathway Information

No matching records could be found.

Structure Information

PDB ID	1DG3
Resolution	1.8
Method	X-RAY DIFFRACTION
Chains	A
Molecule	PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1)
Model	View

Domain Information

ID	Location	Description
cd01851	32-276	GBP
cl21455	32-276	P-loop_NTPase superfamily
pfam02263	18-282	GBP
cl22891	18-282	GBP superfamily
cd00882	42-117	Ras_like_GTPase
cd07648	436-559	F-BAR_FCHO
cl12013	436-559	BAR superfamily
pfam12203	478-559	HDAC4_Gln
cl13614	478-559	ClassIIa_HDAC_Gln-rich-N superfamily
cd10149	479-558	ClassIIa_HDAC_Gln-rich-N
pfam05879	49-120	RHD3
cd10162	479-567	ClassIIa_HDAC4_Gln-rich-N
TIGR01541	435-568	tape_meas_lam_C
cl19901	435-568	Tape_meas_lam_C superfamily
pfam02841	284-580	GBP_C
COG0419	348-588	SbcC
PTZ00121	381-577	PTZ00121
pfam12297	374-568	EVC2_like
pfam04111	505-585	APG6
pfam09731	471-568	Mitofilin
COG1842	437-583	PspA
COG0419	321-592	SbcC
PRK12704	434-591	PRK12704
COG5019	435-557	CDC3
PTZ00121	438-585	PTZ00121
TIGR03319	457-571	RNase_Y
TIGR00618	445-579	sbcc
pfam11600	457-582	CAF-1_p150
COG1196	438-585	Smc
pfam09726	418-582	Macoilin
COG4372	291-563	COG4372
COG4942	296-588	EnvC
COG5394	371-554	COG5394
pfam07111	433-543	HCR
TIGR02169	465-588	SMC_prok_A
COG5185	416-587	HEC1
pfam12128	438-586	DUF3584
pfam11600	484-588	CAF-1_p150
PTZ00121	437-563	PTZ00121

Ontology Information

HPRD ID	4457
Molecular Class	Enzyme: GTPase
Molecular Function	Receptor signaling protein serine/threonine kinase activity (GO:0004702)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO