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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
SND1 27044 staphylococcal nuclease and tudor domain containing 1  7TDRD11, p100 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
17909068   2007Cell line : -

Source : National Cancer Center Hospital, Tokyo, Japan.

Sample Type : CRC tumor and adjacent normal tissues

No. of Sample : 32

Stage : -

real time RT-PCR,Immunoblotting,ImmunohistochemistryUp-regulation-Up-regulation of SND1 may thus occur at a very early stage in colon carcinogenesis and contribute to the posttranscriptional regulation of key players in colon cancer development, including APC and beta-catenin.

20883704   2010Cell line : -

Source : -

Sample Type : -

No. of Sample : -

Stage : -

-Up-regulation-Staphylococcal nuclease homology domain containing 1 (SND1), a component of RISC, is frequently up-regulated in human colon cancers.


Gene Details



NC_000007.13 (127292043..127732659)

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Gene Type protein coding
Gene Family Tudor domain containing
Description -  
Chromosome 7
Location 7q31.3
Start 127292043  
End 127732659  
Strand +  
Gene Sequence

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Length 440617  
OMIM ID 602181   
HGNC ID HGNC:30646   
Unigene ID Hs.122523   
Ensembl ID ENSG00000197157   
PharmGKB ID PA162404053   

mRNA Information


mRNA ID ?NM_014390.2
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS34747.1



Protein Information


      
Protein IDNP_055205.2
Protein Namestaphylococcal nuclease and tudor domain containing 1
Molecular Wt. (Da)0
Protein Sequence

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Length 910  
Uniprot IDQ9NS68
Ensembl Protein ID ENSP00000248484  



Post-translational Modification Information (Source : HPRD)


Residue Type site
YPhosphorylation908;-
YPhosphorylation908;-
YPhosphorylation109;-
YPhosphorylation109;-
SPhosphorylation238;-
SPhosphorylation238;-
TPhosphorylation240;-
TPhosphorylation240;-
TPhosphorylation429;-
TPhosphorylation429;-
SPhosphorylation781;-
SPhosphorylation781;-
SPhosphorylation426
SPhosphorylation426
SPhosphorylation10
SPhosphorylation10
SPhosphorylation3
SPhosphorylation3
KAcetylation193
KAcetylation193
KAcetylation641
KAcetylation641
KAcetylation752
KAcetylation752
TPhosphorylation103
TPhosphorylation103
TPhosphorylation418
TPhosphorylation418

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                                                                                         
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
2960GTF2E11799NP_005504.2in vitro;in vivo7651391   
2961GTF2E21800NP_002086.1in vitro;in vivo7651391   
3516RBPJ920NP_005340.2in vitro;in vivo7651391   
4602MYB1810NP_001123645.1in vitro;yeast 2-hybrid98   090   638   756   344   
4605MYBL23247NP_002457.1in vitro11259168   
5292PIM11292NP_002639.1in vitro;in vivo;yeast 2-hybrid9809063   
6778STAT63302NP_003144.3in vitro;in vivo12234934   


Pathway Information


            
Pathway Name Pathway ID
Epstein-Barr virus infection hsa05169
Viral carcinogenesis hsa05203


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd0017526-166  SNc
cl0014026-166  SNc superfamily
cd00175533-660  SNc
cl00140533-660  SNc superfamily
cd00175350-496  SNc
cl00140350-496  SNc superfamily
cd00175201-328  SNc
cl00140201-328  SNc superfamily
cd04508733-777  TUDOR
cl02573733-777  TUDOR superfamily
pfam00565552-659  SNase
smart00333728-784  TUDOR
pfam0056549-166  SNase
pfam00565367-496  SNase
pfam00565220-328  SNase
cd00175844-895  SNc
cl00140844-895  SNc superfamily
pfam00565850-893  SNase
smart0031821-166  SNc
smart00318525-660  SNc
smart00318193-328  SNc
smart00318341-495  SNc
pfam00567680-799  TUDOR
COG1525345-501  YncB
COG152540-168  YncB
COG1525521-667  YncB
smart00318844-895  SNc
COG1525844-903  YncB
COG1525193-332  YncB


Ontology Information


   
HPRD ID8493
Molecular ClassTranscription regulatory protein
Molecular FunctionUbiquitin-specific protease activity (GO:0004843)
Biological ProcessProtein metabolism (GO:0019538)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO