Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ANKRD1 | 27063 | Ankyrin repeat domain 1 (cardiac muscle) | 10 | ALRP; CARP; C-193; CVARP; MCARP; bA320F15.2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22930170 | 2012 | Cell line : KM 12C, KM 12SM, HT 29 Source : ATCC. Sample Type : - No. of Sample : - Stage : - | Microarray analysis,Real time RT-PCR and Flow cytometry | Up-regulation | - | Gene differentially expressed and analysed bye by Microarray. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Ankyrin repeat domain containing |
| Description | The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system. [provided by RefSeq, Jul 2008] |
| Chromosome | 10 |
| Location | 10q23.31 |
| Start | 90912100 |
| End | 90921275 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 9176 |
| OMIM ID | 609599 |
| HGNC ID | HGNC:15819 |
| Unigene ID | Hs.448589 |
| Ensembl ID | ENSG00000148677 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_014391.2 |
|---|---|
| Exon | join(1..275,928..1107,2008..2145,2304..2411,3446..3544, 5007..5105,5396..5494,5635..5733,8300..9176) | mRNA Sequence | Download Select all |
| Length | 1994 |
CDS Information
| Location | join(249..275,928..1107,2008..2145,2304..2411,3446..3544, 5007..5105,5396..5494,5635..5733,8300..8410) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS7412.1 |
Protein Information
| Protein ID | NP_055206.2 |
|---|---|
| Protein Name | Ankyrin repeat domain 1 (cardiac muscle) |
| Molecular Wt. (Da) | 36121 |
| Protein Sequence | Download Select all |
| Length | 319 |
| Uniprot ID | Q12830 |
| Ensembl Protein ID | ENSP00000307208 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 845 | CASQ2 | 256 | NP_001223.2 | in vitro | 15698842 |
| 7273 | TTN | 1787 | NP_596869.3 | in vitro;yeast 2-hybrid | 14583192 |
| 84665 | MYPN | 10536 | NP_115967.2 | yeast 2-hybrid | 11309420 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00204 | 147-272 | ANK |
| cl02529 | 147-272 | ANK superfamily |
| cd00204 | 182-291 | ANK |
| cd00204 | 127-239 | ANK |
| cd00204 | 214-295 | ANK |
| cd00204 | 246-295 | ANK |
| pfam00023 | 251-282 | Ank |
| pfam00023 | 188-217 | Ank |
| pfam00023 | 221-250 | Ank |
| pfam00023 | 154-183 | Ank |
| smart00248 | 251-280 | ANK |
| pfam13606 | 251-280 | Ank_3 |
| smart00248 | 188-214 | ANK |
| smart00248 | 221-247 | ANK |
| smart00248 | 152-180 | ANK |
| pfam13606 | 188-214 | Ank_3 |
| pfam12796 | 190-282 | Ank_2 |
| pfam12796 | 124-216 | Ank_2 |
| pfam12796 | 157-249 | Ank_2 |
| PHA02874 | 150-289 | PHA02874 |
| COG0666 | 117-302 | ANKYR |
| PHA02876 | 120-297 | PHA02876 |
| PHA03095 | 166-293 | PHA03095 |
| pfam12796 | 223-309 | Ank_2 |
| PHA03100 | 126-288 | PHA03100 |
| PHA02874 | 161-289 | PHA02874 |
| PHA03095 | 131-298 | PHA03095 |
| PHA02878 | 143-300 | PHA02878 |
| COG0666 | 142-291 | ANKYR |
| PHA02874 | 133-289 | PHA02874 |
| PHA02878 | 154-293 | PHA02878 |
| PHA03100 | 166-293 | PHA03100 |
| PHA02874 | 123-306 | PHA02874 |
| PHA03095 | 123-289 | PHA03095 |
| PHA02878 | 123-261 | PHA02878 |
| pfam13637 | 186-239 | Ank_4 |
| PHA02875 | 142-279 | PHA02875 |
| PHA03095 | 149-272 | PHA03095 |
| COG0666 | 150-310 | ANKYR |
| PHA02876 | 130-319 | PHA02876 |
| PHA03100 | 125-279 | PHA03100 |
| PLN03192 | 116-282 | PLN03192 |
| pfam13857 | 243-292 | Ank_5 |
| PHA02875 | 127-280 | PHA02875 |
| PHA02875 | 154-304 | PHA02875 |
| pfam13637 | 221-272 | Ank_4 |
| pfam13637 | 154-206 | Ank_4 |
| pfam13857 | 204-257 | Ank_5 |
| PHA02743 | 202-276 | PHA02743 |
| PTZ00322 | 184-274 | PTZ00322 |
| PTZ00322 | 238-306 | PTZ00322 |
| pfam13637 | 123-172 | Ank_4 |
| PTZ00322 | 172-248 | PTZ00322 |
| TIGR00870 | 159-283 | trp |
| PHA02736 | 190-309 | PHA02736 |
| PTZ00322 | 140-206 | PTZ00322 |
| pfam13857 | 187-226 | Ank_5 |
| pfam13637 | 252-297 | Ank_4 |
| PHA02917 | 244-287 | PHA02917 |
| pfam13857 | 143-193 | Ank_5 |
| PHA02741 | 191-308 | PHA02741 |
| PHA02859 | 149-291 | PHA02859 |
| PHA02878 | 134-239 | PHA02878 |
| TIGR00870 | 144-310 | trp |
| PHA02874 | 219-314 | PHA02874 |
| PHA02946 | 246-299 | PHA02946 |
| PHA02798 | 236-299 | PHA02798 |
| PHA02798 | 198-308 | PHA02798 |
| PHA02716 | 166-289 | PHA02716 |
Ontology Information
| HPRD ID | 2986 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Cell adhesion molecule activity (GO:0005194) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.