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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
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- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23745026 | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 6 CRC and 3 normal tissue Stage : - | Microarray | Up-regulation | 4.845 fold | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008] |
| Chromosome | 8 |
| Location | 8p12 |
| Start | 24241798 |
| End | 24263526 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 21729 |
| OMIM ID | 606393 |
| HGNC ID | HGNC:16299 |
| Unigene ID | Hs.521459 |
| Ensembl ID | ENSG00000134028 |
| PharmGKB ID | PA24535 |
Protein Information
| Protein ID | NP_001138743.1 |
|---|---|
| Protein Name | ADAM-like, decysin 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 470 |
| Uniprot ID | Q96EP1 |
| Ensembl Protein ID | ENSP00000266880 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd04269 | 218-409 | ZnMc_adamalysin_II_like |
| cl00064 | 218-409 | ZnMc superfamily |
| pfam01562 | 42-173 | Pep_M12B_propep |
| cl03265 | 42-173 | Pep_M12B_propep superfamily |
| cd04267 | 218-389 | ZnMc_ADAM_like |
| cd04273 | 218-409 | ZnMc_ADAMTS_like |
| pfam00200 | 429-461 | Disintegrin |
| cl10507 | 429-461 | Disintegrin superfamily |
| pfam13688 | 216-389 | Reprolysin_5 |
| smart00050 | 429-461 | DISIN |
| pfam13583 | 220-377 | Reprolysin_4 |
| cd04272 | 219-408 | ZnMc_salivary_gland_MPs |
| cd00203 | 261-361 | ZnMc |
| pfam13582 | 242-359 | Reprolysin_3 |
| cd11375 | 349-377 | Peptidase_M54 |
| pfam13574 | 240-389 | Reprolysin_2 |
| TIGR03296 | 347-362 | M6dom_TIGR03296 |
| cl21618 | 347-362 | Peptidase_M7 superfamily |
| cd04270 | 222-407 | ZnMc_TACE_like |
| pfam01421 | 218-412 | Reprolysin |
Ontology Information
| HPRD ID | 10811 |
|---|---|
| Molecular Class | Metallo protease |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Regulation of cell cycle (GO:0000074) |
Drug Information
No matching records could be found.