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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
SCAI 286205 suppressor of cancer cell invasion  9FLJ36664, NET40 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
26314959   2015Cell line : SW480, SW620, HT29, HCT116, Colo205

Source : -

Sample Type : -

No. of Sample : -

Stage : -

Wound healing assay,Cell migration and invasion assay,real time RT-PCR,Western blotting Down-regulation-miR-625-3p exerts its oncogenic functions through regulation of�SCAI/E-cadherin/MMP-9 pathways.


Gene Details



NC_000009.11 (127704887..127905838, complement)

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Gene Type protein coding
Gene Family -
Description This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]  
Chromosome 9
Location 9q34.11
Start 127704887  
End 127905838  
Strand -  
Gene Sequence

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Length 200952  
OMIM ID -   
HGNC ID HGNC:26709   
Unigene ID Hs.59504   
Ensembl ID ENSG00000173611   
PharmGKB ID PA165586233   

mRNA Information


mRNA ID ?NM_001144877.2
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS43877.1



Protein Information


      
Protein IDNP_001138349.1
Protein Namesuppressor of cancer cell invasion
Molecular Wt. (Da)0
Protein Sequence

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Length 606  
Uniprot IDQ6ZN28
Ensembl Protein ID ENSP00000328410  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation458

Enzyme Information


No matching records could be found.

PPi Information


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No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam1207063-558  DUF3550
cl1350063-558  DUF3550 superfamily


Ontology Information


   
HPRD ID12381
Molecular ClassUnclassified
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO