Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21575264 | 2011 | Cell line : HCT116, SW620 Source : - Sample Type : - No. of Sample : - Stage : - | Microarray, real-time RT-PCR, Western blotting | Up-regulation | - | Expression of both TIG1 isoforms was observed in normal prostate and colon tissues and was downregulated in colon cancer cell lines. Both TIG1 isoforms suppressed cell growth and stimulated GRK5 expression . |
| 22126303 | 2011 | Cell line : HCT116 Source : - Sample Type : - No. of Sample : - Stage : - | Western blotting,confocal microscope,enzyme immunoassay | Up-regulation | - | TIG1 suppressed PGE2-stimulated Wnt and cAMP signaling pathways in colon cancer cells through GRK5. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008] |
| Chromosome | 10 |
| Location | 10q26.11 |
| Start | 120967197 |
| End | 121215131 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 247935 |
| OMIM ID | 600870 |
| HGNC ID | HGNC:4544 |
| Unigene ID | Hs.524625 |
| Ensembl ID | ENSG00000198873 |
| PharmGKB ID | PA180 |
mRNA Information
| mRNA ID | NM_005308.2 |
|---|---|
| Exon | join(1..285,118832..118927,173131..173243,189011..189088, 215482..215582,217309..217401,222691..222754, 223703..223843,228967..229157,232047..232084, 234315..234404,235860..236068,240439..240576, 244987..245124,245461..245592,247285..247935) | mRNA Sequence | Download Select all |
| Length | 2575 |
Protein Information
| Protein ID | NP_005299.1 |
|---|---|
| Protein Name | G protein-coupled receptor kinase 5 |
| Molecular Wt. (Da) | 67656 |
| Protein Sequence | Download Select all |
| Length | 590 |
| Uniprot ID | Q92766 |
| Ensembl Protein ID | ENSP00000335574 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 484 |
| T | Phosphorylation | 485 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 154 | ADRB2 | 187 | NP_000015.1 | in vitro | 8662852 |
| 552 | AVPR1A | 2894 | NP_000697.1 | in vitro;in vivo | 10858434 |
| 553 | AVPR1B | 2600 | NP_000698.1 | in vitro;in vivo | 10858434 |
| 554 | AVPR2 | 2368 | NP_000045.1 | in vitro;in vivo | 10858434 |
| 624 | BDKRB2 | 213 | NP_000614.1 | in vitro;in vivo | 11517230 |
| 1129 | CHRM2 | 328 | NP_000730.1 | in vitro | 8288567 |
| 5957 | RCVRN | 1558 | NP_002894.1 | in vivo | 12507501 |
| 6010 | RHO | 1584 | NP_000530.1 | in vitro | 82 885 678 144 599 |
| 6620 | SNCB | 3980 | NP_003076.1 | in vitro | 10852916 |
| 6622 | SNCA | 1227 | NP_000336.1 | in vitro;in vivo | 1 061 763 010 852 910 |
| 6623 | SNCG | 4297 | NP_003078.2 | in vitro | 10852916 |
| 6869 | TACR1 | 1208 | NP_001049.1 | in vitro | 12067742 |
| 6915 | TBXA2R | 1768 | NP_963998.2 | in vitro;in vivo | 11504827 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Chemokine signaling pathway | hsa04062 |
| Endocytosis | hsa04144 |
| Morphine addiction | hsa05032 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05632 | 183-495 | STKc_GRK5 |
| cl21453 | 183-495 | PKc_like superfamily |
| cd08752 | 53-175 | RGS_GRK5 |
| cl02565 | 53-175 | RGS superfamily |
| cd05605 | 185-469 | STKc_GRK4_like |
| cd05631 | 185-469 | STKc_GRK4 |
| cd05630 | 185-469 | STKc_GRK6 |
| cd05577 | 192-468 | STKc_GRK |
| cd05607 | 186-468 | STKc_GRK7 |
| cd05608 | 186-468 | STKc_GRK1 |
| cd05123 | 192-448 | STKc_AGC |
| cd05606 | 191-467 | STKc_beta_ARK |
| cd05570 | 190-467 | STKc_PKC |
| cd05633 | 181-518 | STKc_GRK3 |
| cd14223 | 186-502 | STKc_GRK2 |
| cd05580 | 184-467 | STKc_PKA_like |
| cd05578 | 186-448 | STKc_Yank1 |
| cd05571 | 190-468 | STKc_PKB |
| cd05592 | 190-497 | STKc_nPKC_theta_like |
| cd05589 | 186-467 | STKc_PKN |
| cd05575 | 190-485 | STKc_SGK |
| cd05584 | 190-500 | STKc_p70S6K |
| cd05587 | 191-498 | STKc_cPKC |
| cd05583 | 191-451 | STKc_MSK_N |
| cd05573 | 184-497 | STKc_ROCK_NDR_like |
| cd05595 | 190-467 | STKc_PKB_beta |
| cd05616 | 186-498 | STKc_cPKC_beta |
| cd08751 | 35-179 | RGS_GRK6 |
| cd05579 | 194-452 | STKc_MAST_like |
| cd05574 | 186-470 | STKc_phototropin_like |
| cd05614 | 186-484 | STKc_MSK2_N |
| cd05581 | 190-448 | STKc_PDK1 |
| cd05585 | 191-467 | STKc_YPK1_like |
| cd05615 | 191-467 | STKc_cPKC_alpha |
| cd05613 | 186-467 | STKc_MSK1_N |
| cd05590 | 190-467 | STKc_nPKC_eta |
| cd05591 | 190-467 | STKc_nPKC_epsilon |
| cd05582 | 190-467 | STKc_RSK_N |
| cd05594 | 178-467 | STKc_PKB_alpha |
| cd05604 | 190-486 | STKc_SGK3 |
| cd05117 | 190-447 | STKc_CAMK |
| cd05612 | 186-468 | STKc_PRKX_like |
| cd05619 | 181-467 | STKc_nPKC_theta |
| cd05620 | 190-471 | STKc_nPKC_delta |
| cd05593 | 182-467 | STKc_PKB_gamma |
| cd05572 | 192-452 | STKc_cGK |
| cd14209 | 185-467 | STKc_PKA |
| cd08750 | 52-183 | RGS_GRK4 |
| cd05603 | 190-470 | STKc_SGK2 |
| cd05602 | 186-468 | STKc_SGK1 |
| cd05586 | 192-467 | STKc_Sck1_like |
| cd05596 | 186-468 | STKc_ROCK |
| cd05598 | 186-467 | STKc_LATS |
| cd05611 | 194-453 | STKc_Rim15_like |
| cd05600 | 178-468 | STKc_Sid2p_like |
| cd05588 | 190-467 | STKc_aPKC |
| cd05601 | 191-467 | STKc_CRIK |
| cd05618 | 186-501 | STKc_aPKC_iota |
| cd05617 | 186-497 | STKc_aPKC_zeta |
| cd05599 | 184-468 | STKc_NDR_like |
| cd05597 | 186-468 | STKc_DMPK_like |
| cd08724 | 56-169 | RGS_GRK-like |
| cd14007 | 190-449 | STKc_Aurora |
| cd00180 | 192-446 | PKc |
| cd06606 | 190-448 | STKc_MAPKKK |
| cd05122 | 186-448 | PKc_STE |
| cd05624 | 170-468 | STKc_MRCK_beta |
| cd14003 | 190-447 | STKc_AMPK-like |
| cd05621 | 186-497 | STKc_ROCK2 |
| cd08215 | 186-431 | STKc_Nek |
| cd05629 | 184-467 | STKc_NDR_like_fungal |
| cd05622 | 190-468 | STKc_ROCK1 |
| cd05609 | 186-453 | STKc_MAST |
| cd14008 | 192-448 | STKc_LKB1_CaMKK |
| cd08530 | 186-436 | STKc_CNK2-like |
| cd14098 | 190-447 | STKc_Rad53_Cds1 |
| cd05623 | 170-468 | STKc_MRCK_alpha |
| cd14014 | 188-431 | STKc_PknB_like |
| cd05626 | 186-453 | STKc_LATS2 |
| cd06623 | 191-450 | PKc_MAPKK_plant_like |
| cd14006 | 192-446 | STKc_MLCK-like |
| cd05625 | 186-453 | STKc_LATS1 |
| cd14084 | 190-446 | STKc_Chk2 |
| cd14166 | 183-447 | STKc_CaMKI_gamma |
| cd05610 | 192-469 | STKc_MASTL |
| cd14083 | 191-436 | STKc_CaMKI |
| cd14095 | 190-446 | STKc_DCKL |
| cd14081 | 190-448 | STKc_BRSK1_2 |
| cd14168 | 175-447 | STKc_CaMKI_delta |
| cd14099 | 185-448 | STKc_PLK |
| cd14196 | 192-447 | STKc_DAPK2 |
| cd14093 | 191-448 | STKc_PhKG |
| cd14194 | 192-436 | STKc_DAPK1 |
| cd14105 | 192-436 | STKc_DAPK |
| cd06614 | 186-448 | STKc_PAK |
| cd05118 | 186-448 | STKc_CMGC |
| cd14169 | 192-447 | STKc_CaMKI_beta |
| cd05627 | 184-456 | STKc_NDR2 |
| cd14167 | 186-436 | STKc_CaMKI_alpha |
| cd14103 | 192-436 | STKc_MLCK |
| cd14082 | 191-385 | STKc_PKD |
| cd14118 | 192-446 | STKc_CAMKK |
| cd14195 | 192-432 | STKc_DAPK3 |
| cd14009 | 192-436 | STKc_ATG1_ULK_like |
| cd08529 | 192-431 | STKc_FA2-like |
| cd14106 | 192-432 | STKc_DRAK |
| cd08217 | 188-448 | STKc_Nek2 |
| cd14198 | 192-431 | STKc_DRAK2 |
| cd06627 | 192-385 | STKc_Cdc7_like |
| cd14663 | 190-447 | STKc_SnRK3 |
| cd06632 | 185-447 | STKc_MEKK1_plant |
| cd14181 | 183-448 | STKc_PhKG2 |
| cd13994 | 192-436 | STKc_HAL4_like |
| cd14087 | 191-447 | STKc_PSKH1 |
| cd14114 | 192-436 | STKc_Twitchin_like |
| cd14190 | 191-448 | STKc_MLCK2 |
| cd14010 | 189-447 | STKc_ULK4 |
| cd14097 | 190-436 | STKc_STK33 |
| cd05628 | 186-456 | STKc_NDR1 |
| cd14073 | 186-431 | STKc_NUAK |
| cd14094 | 191-450 | STKc_CASK |
| cd14091 | 192-450 | STKc_RSK_C |
| cd08748 | 37-175 | RGS_GRK1 |
| cd14182 | 191-449 | STKc_PhKG1 |
| cd06625 | 187-384 | STKc_MEKK3_like |
| cd07829 | 186-390 | STKc_CDK_like |
| cd14197 | 190-448 | STKc_DRAK1 |
| cd14092 | 186-449 | STKc_MSK_C |
| cd13999 | 192-387 | STKc_MAP3K-like |
| cd07832 | 188-448 | STKc_CCRK |
| cd14185 | 190-447 | STKc_DCKL3 |
| cd14069 | 186-384 | STKc_Chk1 |
| cd14079 | 186-448 | STKc_AMPK_alpha |
| cd14189 | 185-448 | STKc_PLK3 |
| cd14191 | 192-436 | STKc_MLCK1 |
| cd14104 | 192-449 | STKc_Titin |
| cd14192 | 188-432 | STKc_MLCK3 |
| cd14039 | 192-426 | STKc_IKK_alpha |
| cd14184 | 190-447 | STKc_DCKL2 |
| cd00192 | 190-387 | PTKc |
| cd06648 | 186-449 | STKc_PAK_II |
| cd14090 | 191-447 | STKc_Mnk |
| cd14186 | 186-447 | STKc_PLK4 |
| cd14183 | 190-450 | STKc_DCKL1 |
| cd13996 | 184-431 | STKc_EIF2AK |
| cd14038 | 192-385 | STKc_IKK_beta |
| cd08749 | 37-174 | RGS_GRK7 |
| cd14002 | 188-447 | STKc_STK36 |
| cd07831 | 189-448 | STKc_MOK |
| cd06630 | 191-385 | STKc_MEKK1 |
| cd14188 | 190-448 | STKc_PLK2 |
| cd06612 | 184-448 | STKc_MST1_2 |
| cd14088 | 197-436 | STKc_CaMK_like |
| cd14086 | 192-450 | STKc_CaMKII |
| cd14193 | 191-447 | STKc_MLCK4 |
| cd14200 | 188-447 | STKc_CaMKK1 |
| cd06610 | 191-448 | STKc_OSR1_SPAK |
| pfam00615 | 52-170 | RGS |
| cd14080 | 189-448 | STKc_TSSK-like |
| cd14116 | 190-447 | STKc_Aurora-A |
| cd14161 | 183-392 | STKc_NUAK2 |
| cd06657 | 192-448 | STKc_PAK4 |
| cd13989 | 192-426 | STKc_IKK |
| smart00315 | 52-170 | RGS |
| cd14179 | 190-432 | STKc_MSK1_C |
| cd08223 | 190-378 | STKc_Nek4 |
| cd06626 | 188-384 | STKc_MEKK4 |
| cd06658 | 192-449 | STKc_PAK5 |
| cd14071 | 190-448 | STKc_SIK |
| cd06609 | 186-450 | STKc_MST3_like |
| cd08224 | 192-431 | STKc_Nek6_7 |
| cd06605 | 184-448 | PKc_MAPKK |
| cd14113 | 192-431 | STKc_Trio_C |
| cd14096 | 188-431 | STKc_RCK1-like |
| cd06628 | 190-385 | STKc_Byr2_like |
| cd06613 | 192-448 | STKc_MAP4K3_like |
| cd14072 | 186-399 | STKc_MARK |
| cd07833 | 191-448 | STKc_CDKL |
| cd08528 | 189-385 | STKc_Nek10 |
| cd06631 | 191-447 | STKc_YSK4 |
| cd07830 | 190-448 | STKc_MAK_like |
| cd14174 | 191-449 | STKc_Mnk1 |
| cd14173 | 188-447 | STKc_Mnk2 |
| cd08228 | 186-431 | STKc_Nek6 |
| cd14070 | 190-385 | STKc_HUNK |
| cd14115 | 192-447 | STKc_Kalirin_C |
| cd14162 | 190-448 | STKc_TSSK4-like |
| cd14178 | 192-453 | STKc_RSK3_C |
| cd14111 | 193-425 | STKc_SPEG_rpt2 |
| cd14085 | 192-457 | STKc_CaMKIV |
| cd14199 | 188-447 | STKc_CaMKK2 |
| cd14176 | 192-450 | STKc_RSK2_C |
| cd08220 | 190-387 | STKc_Nek8 |
| cd08222 | 186-447 | STKc_Nek11 |
| cd14175 | 192-447 | STKc_RSK1_C |
| cd14180 | 186-432 | STKc_MSK2_C |
| cd07838 | 192-448 | STKc_CDK4_6_like |
| cd14077 | 198-447 | STKc_Kin1_2 |
| cd14046 | 184-436 | STKc_EIF2AK4_GCN2_rpt2 |
| cd08221 | 190-436 | STKc_Nek9 |
| cd06655 | 183-385 | STKc_PAK2 |
| cd13979 | 191-392 | STKc_Mos |
| cd07840 | 192-448 | STKc_CDK9_like |
| cd14172 | 190-432 | STKc_MAPKAPK3 |
| cd14137 | 185-448 | STKc_GSK3 |
| cd14047 | 185-445 | STKc_EIF2AK2_PKR |
| cd13997 | 186-437 | PKc_Wee1_like |
| cd07846 | 191-387 | STKc_CDKL2_3 |
| cd14187 | 180-431 | STKc_PLK1 |
| cd06629 | 192-384 | STKc_Bck1_like |
| cd06647 | 183-385 | STKc_PAK_I |
| cd14171 | 190-447 | STKc_MAPKAPK5 |
| cd08225 | 190-387 | STKc_Nek5 |
| cd14074 | 190-431 | STKc_SNRK |
| cd06659 | 189-448 | STKc_PAK6 |
| cd14202 | 183-448 | STKc_ULK1 |
| cd06654 | 183-385 | STKc_PAK1 |
| cd08218 | 186-431 | STKc_Nek1 |
| cd08229 | 186-431 | STKc_Nek7 |
| cd13978 | 192-394 | STKc_RIP |
| cd13987 | 192-431 | STKc_SBK1 |
| cd13990 | 192-431 | STKc_TLK |
| cd06656 | 183-385 | STKc_PAK3 |
| cd14120 | 192-385 | STKc_ULK1_2-like |
| cd14078 | 189-436 | STKc_MELK |
| cd07836 | 186-388 | STKc_Pho85 |
| cd14107 | 189-448 | STKc_obscurin_rpt1 |
| cd06653 | 186-385 | STKc_MEKK3_like_u1 |
| cd14075 | 189-436 | STKc_NIM1 |
| cd07873 | 185-451 | STKc_PCTAIRE1 |
| cd14089 | 190-446 | STKc_MAPKAPK |
| cd14117 | 182-449 | STKc_Aurora-B_like |
| cd14109 | 206-448 | PK_Unc-89_rpt1 |
| cd06621 | 190-455 | PKc_Pek1_like |
| cd14133 | 191-448 | PKc_DYRK_like |
| cd08219 | 190-391 | STKc_Nek3 |
| cd07871 | 185-395 | STKc_PCTAIRE3 |
| cd14052 | 186-377 | PTKc_Wee1_fungi |
| cd05576 | 187-448 | STKc_RPK118_like |
| cd06651 | 178-447 | STKc_MEKK3 |
| cd07834 | 190-448 | STKc_MAPK |
| cd07880 | 178-448 | STKc_p38gamma |
| cd14076 | 190-447 | STKc_Kin4 |
| cd14119 | 192-448 | STKc_LKB1 |
| cd07841 | 192-379 | STKc_CDK7 |
| cd06611 | 192-450 | STKc_SLK_like |
| cd14201 | 191-387 | STKc_ULK2 |
| cd06641 | 186-384 | STKc_MST3 |
| cd07866 | 185-448 | STKc_BUR1 |
| cd14066 | 192-437 | STKc_IRAK |
| cd14131 | 187-447 | PKc_Mps1 |
| cd13985 | 190-431 | STKc_GAK_like |
| cd07869 | 184-390 | STKc_PFTAIRE1 |
| cd14004 | 190-431 | STKc_PASK |
| cd07856 | 182-388 | STKc_Sty1_Hog1 |
| cd06652 | 186-385 | STKc_MEKK2 |
| cd06622 | 192-447 | PKc_PBS2_like |
| cd07860 | 186-390 | STKc_CDK2_3 |
| cd14108 | 192-448 | STKc_SPEG_rpt1 |
| cd14165 | 190-448 | STKc_TSSK1_2-like |
| cd06624 | 191-385 | STKc_ASK |
| cd06620 | 187-385 | PKc_Byr1_like |
| cd14170 | 190-436 | STKc_MAPKAPK2 |
| cd07847 | 192-390 | STKc_CDKL1_4 |
| cd13982 | 294-448 | STKc_IRE1 |
| cd14102 | 191-405 | STKc_PIM3 |
| cd07855 | 190-448 | STKc_ERK5 |
| cd06644 | 192-455 | STKc_STK10 |
| cd14050 | 191-436 | PKc_Myt1 |
| cd07848 | 184-390 | STKc_CDKL5 |
| cd07865 | 184-378 | STKc_CDK9 |
| cd07851 | 184-449 | STKc_p38 |
| cd07844 | 185-448 | STKc_PCTAIRE_like |
| cd07835 | 192-390 | STKc_CDK1_CdkB_like |
| cd14665 | 192-447 | STKc_SnRK2-3 |
| cd06645 | 178-447 | STKc_MAP4K3 |
| cd06642 | 186-385 | STKc_STK25 |
| cd06615 | 186-384 | PKc_MEK |
| cd14100 | 191-405 | STKc_PIM1 |
| cd06618 | 177-449 | PKc_MKK7 |
| cd07879 | 192-388 | STKc_p38delta |
| cd07876 | 186-387 | STKc_JNK2 |
| cd06640 | 186-384 | STKc_MST4 |
| cd07872 | 185-387 | STKc_PCTAIRE2 |
| cd14177 | 192-385 | STKc_RSK4_C |
| cd07870 | 192-433 | STKc_PFTAIRE2 |
| cd06637 | 186-455 | STKc_TNIK |
| cd07878 | 186-448 | STKc_p38beta |
| cd14000 | 191-387 | STKc_LRRK |
| cd07877 | 178-423 | STKc_p38alpha |
| cd13986 | 185-385 | STKc_16 |
| cd07863 | 270-390 | STKc_CDK4 |
| cd14121 | 192-447 | STKc_ULK3 |
| cd07864 | 191-399 | STKc_CDK12 |
| cd06608 | 184-447 | STKc_myosinIII_N_like |
| cd07861 | 192-390 | STKc_CDK1_euk |
| cd06638 | 164-431 | STKc_myosinIIIA_N |
| cd06646 | 176-384 | STKc_MAP4K5 |
| cd07862 | 192-390 | STKc_CDK6 |
| cd14048 | 184-423 | STKc_EIF2AK3_PERK |
| cd07857 | 294-388 | STKc_MPK1 |
| cd06917 | 186-387 | STKc_NAK1_like |
| cd14146 | 191-387 | STKc_MLK4 |
| cd14210 | 189-391 | PKc_DYRK |
| cd13991 | 192-385 | STKc_NIK |
| cd05084 | 192-401 | PTKc_Fes |
| cd05081 | 191-378 | PTKc_Jak3_rpt2 |
| cd07837 | 192-390 | STKc_CdkB_plant |
| cd14110 | 182-385 | STKc_obscurin_rpt2 |
| cd14164 | 190-387 | STKc_TSSK6-like |
| cd14135 | 189-388 | STKc_PRP4 |
| cd14061 | 191-387 | STKc_MLK |
| cd06643 | 192-447 | STKc_SLK |
| cd05085 | 191-399 | PTKc_Fer |
| cd06636 | 186-385 | STKc_MAP4K4_6_N |
| cd07849 | 185-388 | STKc_ERK1_2_like |
| cd14662 | 190-447 | STKc_SnRK2 |
| cd07845 | 180-449 | STKc_CDK10 |
| cd14226 | 174-390 | PKc_DYRK1 |
| cd05068 | 172-399 | PTKc_Frk_like |
| cd05041 | 192-399 | PTKc_Fes_like |
| cd07874 | 186-388 | STKc_JNK3 |
| cd05038 | 190-378 | PTKc_Jak_rpt2 |
| cd13974 | 283-445 | STKc_SHIK |
| cd06650 | 184-384 | PKc_MEK1 |
| cd13983 | 191-385 | STKc_WNK |
| cd14225 | 191-390 | PKc_DYRK4 |
| cd05034 | 190-399 | PTKc_Src_like |
| cd05072 | 181-388 | PTKc_Lyn |
| cd07850 | 186-388 | STKc_JNK |
| cd14203 | 192-399 | PTKc_Src_Fyn_like |
| cd07875 | 186-388 | STKc_JNK1 |
| cd06649 | 186-413 | PKc_MEK2 |
| cd05097 | 183-378 | PTKc_DDR_like |
| cd14163 | 190-448 | STKc_TSSK3-like |
| cd14101 | 188-431 | STKc_PIM2 |
| cd14158 | 190-422 | STKc_IRAK4 |
| cd07852 | 302-388 | STKc_MAPK15-like |
| cd06619 | 188-385 | PKc_MKK5 |
| cd14147 | 185-387 | STKc_MLK3 |
| cd14027 | 192-385 | STKc_RIP1 |
| cd14036 | 190-385 | STKc_GAK |
| cd13993 | 190-386 | STKc_Pat1_like |
| cd14005 | 188-448 | STKc_PIM |
| cd05067 | 181-388 | PTKc_Lck_Blk |
| cd14224 | 190-390 | PKc_DYRK2_3 |
| cd14062 | 233-387 | STKc_Raf |
| cd14664 | 192-385 | STK_BAK1_like |
| cd14017 | 188-391 | STKc_TTBK |
| cd14058 | 192-385 | STKc_TAK1 |
| cd07843 | 195-390 | STKc_CDC2L1 |
| cd05070 | 181-399 | PTKc_Fyn |
| cd06639 | 176-385 | STKc_myosinIIIB_N |
| cd14019 | 184-385 | STKc_Cdc7 |
| cd06616 | 192-478 | PKc_MKK4 |
| cd05069 | 181-399 | PTKc_Yes |
| cd05045 | 190-387 | PTKc_RET |
| cd07859 | 186-451 | STKc_TDY_MAPK |
| cd14212 | 189-390 | PKc_YAK1 |
| cd05060 | 192-389 | PTKc_Syk_like |
| cd07858 | 192-388 | STKc_TEY_MAPK |
| cd05035 | 190-387 | PTKc_TAM |
| cd14059 | 291-387 | STKc_MAP3K12_13 |
| cd06617 | 192-448 | PKc_MKK3_6 |
| cd14148 | 191-386 | STKc_MLK2 |
| cd07842 | 294-399 | STKc_CDK8_like |
| cd07854 | 186-463 | STKc_MAPK4_6 |
| cd05083 | 192-385 | PTKc_Chk |
| cd05073 | 181-405 | PTKc_Hck |
| cd14064 | 192-385 | PKc_TNNI3K |
| cd05071 | 181-399 | PTKc_Src |
| cd05148 | 183-399 | PTKc_Srm_Brk |
| cd14145 | 259-387 | STKc_MLK1 |
| cd05032 | 190-406 | PTKc_InsR_like |
| cd14149 | 233-385 | STKc_C-Raf |
| cd05074 | 190-458 | PTKc_Tyro3 |
| cd14150 | 233-385 | STKc_A-Raf |
| cd05061 | 190-453 | PTKc_InsR |
| cd07839 | 192-384 | STKc_CDK5 |
| cd14151 | 233-385 | STKc_B-Raf |
| cd14205 | 192-378 | PTKc_Jak2_rpt2 |
| cd14227 | 184-390 | STKc_HIPK2 |
| cd14229 | 185-390 | STKc_HIPK3 |
| cd05080 | 183-451 | PTKc_Tyk2_rpt2 |
| cd05095 | 185-436 | PTKc_DDR2 |
| cd05075 | 190-387 | PTKc_Axl |
| cd05096 | 192-379 | PTKc_DDR1 |
| cd05047 | 191-387 | PTKc_Tie |
| cd05062 | 181-403 | PTKc_IGF-1R |
| cd14222 | 192-382 | STKc_LIMK2 |
| cd07440 | 60-169 | RGS |
| cd14065 | 192-379 | PKc_LIMK_like |
| cd05116 | 192-389 | PTKc_Syk |
| cd05082 | 190-396 | PTKc_Csk |
| cd05044 | 190-388 | PTKc_c-ros |
| cd05090 | 234-402 | PTKc_Ror1 |
| cd14228 | 184-390 | STKc_HIPK1 |
| cd06633 | 192-449 | STKc_TAO3 |
| cd14067 | 292-390 | STKc_LRRK1 |
| cd14204 | 181-387 | PTKc_Mer |
| cd14049 | 184-431 | STKc_EIF2AK1_HRI |
| cd14159 | 192-444 | STKc_IRAK1 |
| cd13995 | 189-388 | STKc_MAP3K8 |
| cd05054 | 190-387 | PTKc_VEGFR |
| cd14056 | 285-379 | STKc_TGFbR_I |
| cd14026 | 190-385 | STKc_RIP2 |
| cd05055 | 159-387 | PTKc_PDGFR |
| cd13988 | 192-391 | STKc_TBK1 |
| cd14154 | 192-379 | STKc_LIMK |
| cd14011 | 277-450 | PK_SCY1_like |
| cd05115 | 192-397 | PTKc_Zap-70 |
| cd14041 | 179-436 | STKc_TLK2 |
| cd14143 | 292-359 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd14060 | 193-387 | STKc_MLTK |
| cd05103 | 286-403 | PTKc_VEGFR2 |
| cd14136 | 292-381 | STKc_SRPK |
| cd07853 | 294-384 | STKc_NLK |
| cd14040 | 179-436 | STKc_TLK1 |
| cd14140 | 303-444 | STKc_ACVR2b |
| cd05098 | 192-387 | PTKc_FGFR1 |
| cd14221 | 192-379 | STKc_LIMK1 |
| cd13998 | 298-378 | STKc_TGFbR-like |
| cd14141 | 287-378 | STKc_ACVR2a |
| cd14144 | 297-378 | STKc_BMPR1 |
| cd05058 | 190-386 | PTKc_Met_Ron |
| cd05101 | 192-387 | PTKc_FGFR2 |
| cd13975 | 246-381 | PKc_Dusty |
| cd05048 | 192-387 | PTKc_Ror |
| cd05112 | 234-398 | PTKc_Itk |
| cd14022 | 284-448 | PK_TRB2 |
| cd05079 | 183-379 | PTKc_Jak1_rpt2 |
| cd14207 | 286-387 | PTKc_VEGFR1 |
| cd05114 | 190-413 | PTKc_Tec_Rlk |
| cd05043 | 181-398 | PTK_Ryk |
| cd14220 | 289-378 | STKc_BMPR1a |
| cd06635 | 186-385 | STKc_TAO1 |
| cd07867 | 287-393 | STKc_CDC2L6 |
| cd05100 | 192-387 | PTKc_FGFR3 |
| cd14025 | 189-389 | STKc_RIP4_like |
| cd14134 | 183-386 | PKc_CLK |
| cd05059 | 231-408 | PTKc_Tec_like |
| cd07868 | 287-393 | STKc_CDK8 |
| cd14016 | 186-335 | STKc_CK1 |
| cd05039 | 192-401 | PTKc_Csk_like |
| cd06607 | 296-385 | STKc_TAO |
| cd05089 | 191-387 | PTKc_Tie1 |
| cd14211 | 191-390 | STKc_HIPK |
| cd05036 | 179-388 | PTKc_ALK_LTK |
| cd05063 | 190-385 | PTKc_EphR_A2 |
| cd05088 | 191-387 | PTKc_Tie2 |
| cd05102 | 286-387 | PTKc_VEGFR3 |
| cd14132 | 189-448 | STKc_CK2_alpha |
| cd14023 | 269-448 | PK_TRB1 |
| cd14142 | 284-360 | STKc_ACVR1_ALK1 |
| cd14155 | 192-379 | PKc_TESK |
| cd05057 | 181-387 | PTKc_EGFR_like |
| cd14214 | 192-386 | PKc_CLK3 |
| cd13976 | 284-448 | PK_TRB |
| cd05099 | 292-387 | PTKc_FGFR4 |
| cd06634 | 186-385 | STKc_TAO2 |
| cd05053 | 298-408 | PTKc_FGFR |
| cd05091 | 293-402 | PTKc_Ror2 |
| cd05109 | 186-387 | PTKc_HER2 |
| cd14037 | 190-385 | STKc_NAK_like |
| cd05105 | 266-387 | PTKc_PDGFR_alpha |
| cd14053 | 287-379 | STKc_ACVR2 |
| cd05050 | 181-397 | PTKc_Musk |
| cd05108 | 186-387 | PTKc_EGFR |
| cd05113 | 192-419 | PTKc_Btk_Bmx |
| cd14054 | 301-377 | STKc_BMPR2_AMHR2 |
| cd05046 | 191-397 | PTK_CCK4 |
| cd14068 | 191-381 | STKc_LRRK2 |
| cd05065 | 191-385 | PTKc_EphR_B |
| cd05033 | 190-385 | PTKc_EphR |
| cd05052 | 192-387 | PTKc_Abl |
| cd14055 | 298-357 | STKc_TGFbR2_like |
| cd05066 | 190-385 | PTKc_EphR_A |
| cd13981 | 192-382 | STKc_Bub1_BubR1 |
| cd05056 | 286-397 | PTKc_FAK |
| smart00220 | 186-448 | S_TKc |
| pfam00069 | 186-448 | Pkinase |
| PTZ00263 | 192-464 | PTZ00263 |
| COG0515 | 186-543 | SPS1 |
| PTZ00426 | 178-487 | PTZ00426 |
| smart00221 | 190-387 | STYKc |
| smart00219 | 190-387 | TyrKc |
| pfam07714 | 186-409 | Pkinase_Tyr |
| PHA03390 | 195-450 | pk1 |
| PLN00034 | 190-385 | PLN00034 |
| PTZ00024 | 192-390 | PTZ00024 |
| PTZ00267 | 253-436 | PTZ00267 |
| PTZ00283 | 190-431 | PTZ00283 |
| PRK13184 | 190-445 | pknD |
| PHA03209 | 232-418 | PHA03209 |
| PHA03207 | 207-447 | PHA03207 |
| PTZ00266 | 184-431 | PTZ00266 |
| PHA03210 | 188-379 | PHA03210 |
| PLN00009 | 192-390 | PLN00009 |
| PTZ00036 | 181-388 | PTZ00036 |
| PHA03212 | 194-382 | PHA03212 |
| PHA03211 | 292-418 | PHA03211 |
| TIGR03903 | 293-460 | TOMM_kin_cyc |
| COG4248 | 281-387 | YegI |
Ontology Information
| HPRD ID | 1588 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Oxidoreductase activity (GO:0016491) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.