CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
GPX3	2878	Glutathione peroxidase 3 (plasma)	5	GPx-P; GSHPx-3; GSHPx-P

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22371331	2012	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	TagSNP Selection and Genotyping	Polymorhpism	-	Genetic variability in GPX3 contributes to risk of rectal cancer but not of colon cancer and thusprovide additional support for differences in underlying pathogenetic mechanisms for colon and rectal cancer. The homozygous variant genotypes of rs3828599, rs736775 and rs8177447 in GPX3 were associated with a 40-50% risk reduction for rectal cancer, specifically for rectal cancers with TP53 mutations.

Gene Details

Chromosome: 5; NC_000005.9 (150399999..150408554)
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Gene Type	protein coding
Gene Family	-
Description	This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]
Chromosome	5
Location	5q23.2
Start	151020438
End	151028993
Strand	+
Gene Sequence	>gi\|568815593:151020438-151028993 Homo sapiens chromosome 5, GRCh38.p2 Primary Assembly GTCGCCCCGGGACGGGGAGGTGGGGAGCTGAGGGCAAGTCGCGCCCGCCCCTGAAATCCCAGCCGCCTAG CGATTGGCTGCAAGGGTCTCGGCTTGGCCGCGGATTGGTCACACCCGAGGGCTTGAAAGGTGGCTGGGAG CGCCGGACACCTCAGACGGACGGTGGCCAGGGATCAGGCAGCGGCTCAGGCGACCCTGAGTGTGCCCCCA CCCCGCCATGGCCCGGCTGCTGCAGGCGTCCTGCCTGCTTTCCCTGCTCCTGGCCGGCTTCGTCTCGCAG AGCCGGGGACAAGAGAAGTCGAAGGTGAGTGAGCCTCCGGGCCGGGGGCCGGGAGAAAAAACCTAGCCCC TCGGTGTCCAGCGCTCAGTGCAATGCACCCCTTTTCCCAGGCTCCCCGCCAGATGGGCAATCCCCAGGTG CGAGAGACCTCCTGAACCCCTTTTGCCGCCCCCTCCGCCGCCGGGACCCCGCCCCCGACCGTCGTCGTCT CGTAGTTCCATCTGTTGGAGAGCCGAGACCTGGTGCTTCAGGCGGGCAGAATGACTAAGGGAGGAAGGTC TCTCTCCCCGAGCTCGCACTTTCTCCCCACTGCCACCTCGAGGGTCGCCTTGCTACATCTATGTCACCTC CGTGCCTGAGCTGCTCCCCTTCAGTAGGGCCTAAGAGGGAGGGCGTCACAGAAAAAAATGCCCAGCGTCT GGGTGGGCTGTGCAAGTTCCCAGGGAGAGAGACAAGGAGAAAGGAGAGAGGCAGCTGGGTGGTCCTGGTC CTGAAGAACTGCTGTGGGGGGCTCTTCTACCCCAAGAATGATACAGGCAGGTAGAAATGGCCACTTGGAT TCAGGGCATTGGTAGAAGAGGCAGAGATCTGTGCTAGAAAGAGCTCTGGAGTGACAGTGCAGAACACTCA GGACCCTGAGTCCTTACCTGCTCCTGGACCCCCGTTTCTCCATCTGCAGGGGAGAGTTTGGGGGTGGGAG TGCATGGGGCACAATGAAGCTGAGGGCCTCAGAGGGGATGCTTGGAGAAGCTGAAAAATCCACAAGCTGT TCTCTGAAATTTCCTCCCCTGGGGCAGCCTCACTACCCAGGACCCACTGTCCTCATTAGCCTGAGGAAAC CTGGTAGTTGGAGAAAGCTGGGGACTGCTAATTCAGAAGAAGAGGTAGAATTCTCTAGAGCCTCAGTCTA TTTCCAGCAGGTGTGTGGCCCACACCTGGAGTGGGGATACTGAGGCCAGGAGTGGGATGACCCAGCATGC TTATCTCCTTTGACAGTATGTACTGGGGTGGGCTCTGTAGACCTCTCCTCTACCCAGGGAGTGGGAGTGG GTGGGGAAGGAGGCAGAAGCCAGGTGTAGGGATAGACTCAAAGCGAGCGATTTCTGTCTCCAACTTCCCA ACATGCATAACTCACATTTTTGCAAGCTCTGAGCTTTTGTTTCTAAAATCCTCTGGGTCTTCACTTTAAT TAAGTTCTTATGAGTCTAGGATTCCGTTTCCAAAATTCTGTCCACTTCTCAGGAAGCCCATTGGAAGCAC AGGGTTCCTTCCATGTTACTCACCCCTTTTCGGTCCTCAGCCTAAATCCGATTAATCAGCCTCTCCTTGG AGTCAGTCTAAATGGATGTGAAGCCACTTCGTCCAAGTCCCCTCCTTTTTATCCATCCCTGTTCATAATC CCCAACTCAGAAGGCATTTTCCAGGTCAGGAATGGGATCGATTTTCAACATTGAGGTTTGGGGTGGGCCA TAGACAGGCCAGCACCGTGGAGTCAGTCCCAACCTTCAGTTTTGGAAAGGTCAAAGAAGATACAATTGGG CCCTGCCTCAAGAAGGCTAGTGGGGAGAACGTGGACTCCATGAATAACTCATCATAGCTGTGTCTTCTCT GCAGCACTCTGGGGAAGGATAAATGGACTCAGAGAGAATAGGATGGGGATGGTCTAGAAAAGTTTTAGGG TGAGGTGTGATCATATCACATACAACCAGTCAGGACTTGCTGGCTAATGAAAGCCTGGGCATGCCCATCT CTGCTCCCAAGTTCTTAGAGTTCAGATGTCTTAGCTCTGGGTTAGGACCCAACCACTCACCTTACCCCCA ACCCCAGGGTAAAGAGATAGGGTTATGGGGCATGTGGAGAATGGAATGGACGAAAGGTGACTCAGCCCCA GAGAGGTGTTTTCCTCCTACCAATTGAAAGGGAGATGCTAGGGAAGAGACCAGGTCCTCCTCTTCTTGCT GCGTCACCTCCCCAGTCCAACTTCAGGCTGCCCACGCTCCTTGTCTCTACAAAAGGACTGCAGAAGCCGG AAAGAGTGACAACTGCTGACGTGCACGGGATCCTAGTAACTGCTGGTTTCTAGGTGACTAAACCTGGCAG AGAGAATCATGGAACCACAGGCTGACAGAGTTAAAGGGCCCTTAAGACAGCCCTGAACCTGACTCCATCT TACAATGGAGGAGCTGGAGCCCCAGCAAAGGGGGTCACATGGCATCAGAGACACAGCAAAGCCCAGCACT CAGGTCTCCTGACTCCCAGACCACTTCTCACAGCATCATATTGATAGGAGTAATAAGACGGGAGAGGAGA AAGACACAAGACCAGCAGCCCCAGCCAGCCAGAGTCCTGGCTGAGTCCCATCATCCAACTCTCAAGCCAT TGGAACCCTCTTCTCTTGCCCGGCTGTGGGAGGATTCAGGCACCCTCATGGCCTCTCCCCTTATCTCCTC TGGCCACTGTTTCAGATGCGGTGCTCTGGGATTCCACGTGCCCAGAGAAGGGAAGGGGGCTCATAGAGGA CTGAGTTGCAGTGATCAGTGGTGAGCACAGCCGTGGCTCTCCACCCATGGGCCACCTTCTGACCCCCACT ATCCCTTGACATGAGATTTCGTTCCAAGAGACTCCAGGCCTGTTTTGCTCTGCCAGCAGATTCCCACAAC CATTTTGGGCAGCAGCATGCTTATCTCCCTGGACATATGCCCAGACAGTGTAAGTGACTTGCTCAGGGCC ACACAGCCAGCAAAAAATAGAACCTAATGAAATAGGGTTCTCCTTGCCACACCCCCAAGCTGAAACTGTG CCCAGAAGCTGGTCCTTCTGTTTACAAGTTCCCATTATTAGGACAACCTGTAATCTTTTTTTCCTCCATG TCTCAGAGTTCATTTTTGGATCATGGCAGAGTTAAAAAAGTGGAGAGGCTATAGACATGCCTGGCTTTCT GGCCACTAGATCTTTGTGGCGGTCTAGGGTGTATTTGTTGTGCCCCAGTTTGTCTGCATTTTAAGGCGGA ACTGGCCCTGGCTGGGAACGAGGAGGTCCAGGAGCAGTAGGAATGTTGATCTTAGGTCTTGGGCCTGCCT CCAGCACCCACCAAAAGTCACCGGATGTGGAATATTAGACTCATGTAAAGCAGGAAGTTTGCACCAGAGC CAAGAAGAGAGCTTGCAGCTGCCAGGGAATGGCCTGGCGGAGGAAGCGCAGCCTCGCCCAGCTCAGCAGA CCTGCTTCATGACAGAGGCAGCTCTTCTGCACTCTACTGGGGCCACGCCCTGCCAGCATATATCACTCCC TTCACCTGGTCAGGCCCAGGTACCTTGCCTCAACAGCAAGTTCTCCAGAATTGAGGGGAAGAGAGGGAGT GAATTTGCTTCTCTAACTCCAGCCACCTGTCTCTGCCCTCTCCTGGTCTATAATGCTACTTTGCATTCCA TTTGTTTATTGTCTGCCCACCTCTCAAAGGATATCAGGGCCACAAAGGACCTTAAAGACCACCTTATACA ATGGTTTCAAGGTTTCTCCTTTCCCATCACGACCAGCCCACCTGCCAAATTGTGTCAATGATGCAATGAC ATCCTTTCAAGAATAGTCTCAGAATTTTGTTGTCTGTGTCACGGGCAGAGTAGGCTCATAGGCCACATCC TACTAGCCAGCAGTGACCCCAATCCCCTCTCTCCCACTGATCATGATCCTATCAAGCCATCATGGTTGAC CTGGTTGGAGAGTTGGTTCAGTTCAAGGTTCTCATTTTATAAATGAGGAAACTCAGGTCCGAAGAAAAGA AAGGGCCAGTCCAAGACCACACAGGGAGTTAATGGCAAAGGGACATGGAGCCCAGGTCTCCCAGCCCACA GTCCACTGCACTCTGTCCCTCCTTGTCCTGGAGGCTGACTGTGAGCAGCAGCTGGGGAGGGAGGAAGGCA TAAGGGTCATCACCAGCCTGCTCAGACCCGGAACATTAACACATGCAGGTACTGTTGCTTTTCCCTACCT CACCACAGCCCTTTCCCCCATGCCTGGCTCTCAGTCCTGCTTCCCTATTTGGTAACAACAGCTTCATCTT TCCTGTCCTGCAGATTGGGAGCCTCTGAATCACCATGTCCATACGGCCTCTTCCTCCTTTCTGTTCAGTT TTTCCTTCACACTGGCCTAGTTCAGGTTCTCATCCTCAATTGCCTGGATTATTCCAACAGCCACCCAACC AGTCTCCATCAGCCCGTCTAGGAACCCAGTCATCAGCTTTAGGGCAGTCTCCCTGAGAGCCCAGTAAATG TTCTGAAATTGACATGTGATGTGGAAGTAATTAGCAAAATAAGTCATTCTCCAGGGTTCCATAGCACTCA CTTATTAAGTGCTTAATATTAATAAGTGCTTATTAGGTGCTTAATATTAATAAGTGCTTTTTAAGCACTT AATATTAAGTACCCGAAAAGCACTTATTAAGTGCTTTCATAATCATTATCTTAAACAAGGAATTAGGAGA CGTCAGTGCTAGTCCAGTTCCAATTCTCGGTGATTACTTTGAGAAAGTCACTCTCTCTGTTGGGATCTTT CATTCTTTTGAAAACGGAGATGTCCAAGTTCCTTTCCAGCTCTAACTGCTCCTTTTATGGCCTGTGTTCC AGATGGACTGCCATGGTGGCATAAGTGGCACCATTTACGAGTACGGAGCCCTCACCATTGATGGGGAGGA GTACATCCCCTTCAAGCAGTATGCTGGCAAATACGTCCTCTTTGTCAACGTGGCCAGCTACTGAGGCCTG ACGGGCCAGTACATTGGTAAGAGCCCACCCTTCCTCCCTGCTTTATTTGGGGCTGTATGGCATATTTCAA TCACAGGAGCTTTTCTGGTGCATGGGGGAAAGGGTGATGGCAATCACGAGAGTCCAAGCCCCTTTTCTCA GCTCCACTGTGTTCCGTGGTTTTGTGAAGATGATTATATAAGCCTGAGGTCTGATTGCCTTTGGACATGT TCTAGGAGATTCCTAGTTATCCTTCTTCATCTCTGGGCACCTCAACAACCCTAAAGGCAGAGGGATAGAG ATTAGGTTTGTGCTTAGAGCTCCCTTTGGCTGGAGCATGAGATGGTAACTGAAGCTCCATCTTGCTGAGA ATATCTTATTTTCCCTCAGCCCCATCTGCTTTGGTGCTTCTCTTGGCAGCTCTCTGGAAAGCAGGCAATT GCCTCGAGGCCCCAGAGTGTATGCGTGGTGTAGCGGGATGAAGGAGCAGGCTACACTTCTAATGCCCATT CTAAAATAAACTTTGAAGATGATCTAGTTTAGCCTTCCCCTCTTCTCAATCTACACATGGGAAACCAAGA CTCAGAGCGAAGATACAACTTAAACAGGGTCACAAAGCTATTAGCGGTGGAATGGGGCATTTGGCGCAGG TTTCATGATCTCCTGATATGCTTACTCCTTTCTCCCTAGCTGGGGTAGAATACAGAGGCTAGGGGAACAG GCAACCAAAGGCAAGCGACAGCACCCAGGGGAAAACGCTTTGGGGCTGAGCAGTCTACTGGCAGGGGGTC AGGGAGGCAAGGGCAATTTGACCCTCCATGCTCTGCCTGGCAATCACAGGCGAATTCCCGGAAGTGAAAG GACGGCGGTCACGTGGCCCAGTGGCTGTGAGTGCTTTTTCTGGGATGCTTCTCTCTAGCCTTGGAACAGA GCAGAGTGCGTTTGGGCAAGAGATGGGCTGGGTGCTGCTGCAAAAGAGACCAGGGGACACTGAGGAAACT GGGGAGCTGGGCCAGGGCCTCATCTGTGTTCCTGATTTGCCAAAGATTATGGGAGGGTTGTAACCTCACC CCAAAGAAGTTCTCTGCCTTGTATCCAGGGATGGATAGTTCTTGCTCCAGAAAACTCAATCCTGAGGGTT CTGAATGAGTGCTCTAGCTGGCCCAGGTGGAGGGCCTTGGCAATGGGCAGGTGACTGACAGCTGACTTGA GGAAGGGTATTATTCTTGTCCTCCAAACCTCCAATCCATCCAGATTAGAGTCAAGAGGATAGGACCTGAG TCCCAGCATTGCTGTGAACTCACTGGTGATCCTGCGCAAGTCCCTCCCTTTCTCGGGCCTCAGTAGTTCC AGCGGCACAGCGGGTGAGCCGGGGGAGTGGTGTGGATGAGACAGGGCTCCTCGCCAGGATACTCCCACAT CTGCTCTTTCTCTTTGGCCCAGAACTGAATGCACTACAGGAAGAGCTTGCACCATTCGGTCTGGTCATTC TGGGCTTTCCCTGCAACCAATTTGGAAAACAGGAACCAGGAGAGAACTCAGAGATCCTTCCTACCCTCAA GTGAGTACTCACTCAGCATCCTGAGAAAGCTCCTCTCACATGGCCCACATCTTGTTATCAACCCCAAATC ATGGTGGACATTTATCGGCCACCAAGAACTACTCTCCTCTTCTAGGATCCCCAGTGGAATGAGGGAAGGG AAGGGACAAGAGAGGGAGAAGGACAGGGACAACTGGTTGTGATGTGCATCCGCAGGGAGCACCAAGGTTG AGGGACACTGAAAAGGGACCAGGCTAGAAAGGAAGACCGTGGACTCACATTATGCCTATGCCCACTGCAC ATTCACTGGCTCCTGCTGCCCACTGCAGAATAAATCCAGACTCCCAACACCCTCTCCCCTGTTCTGTCCC TTCCTCTCATTTCTGAGCCCTGTGCCCACCTCCTTGGGACCCACCTAAGAACATTTCTCAACAGGTATGT CCGACCAGGTGGAGGCTTTGTCCCTAATTTCCAGCTCTTTGAGAAAGGGGATGTCAATGGAGAGAAAGAG CAGAAATTCTACACTTTCCTAAAGGTAAGTGAGCTGCCACCTGTGCTGGCTGGGGCTGCAGCCCCTCCTG GCTCCAGCCCACAGCGTCAGGGCCCATGCCACCTCCCCTGCTCCTGGGCTCTTGGGGAATTTCTTGGCAC CTGACTATTGTTCCAACTAGAGGGCTCTGCAGACCCTGACTAGGGTCTCATTGGCCCATTTTACAGAAAG GCCCAGAAGGACCCAGAGTGAACATACTAAGGGTCTCACAATCTTCTAGAGCCACAGCTGGCGCTGGCAG TCTTCTAACTCCCAAACTGGGGCTCTTTTCTCAGGGCCAGGCTATTCCCCAGGAAGGCCTGGGAAGGAAG AGGGTCAGGGGGCCTCAAGCAAGGTTGACACTCCTCTTATCCCTGCTCTAGAACTCCTGTCCTCCCACCT CGGAGCTCCTGGGTACATCTGACCGCCTCTTCTGGGAACCCATGAAGGTTCACGACATCCGCTGGAACTT TGAGAAGTTCCTGGTGGGGCCAGATGGTATACCCATCATGCGCTGGCACCACCGGACCACGGTCAGCAAC GTCAAGATGGACATCCTGTCCTACATGAGGCGGCAGGCAGCCCTGGGGGTCAAGAGGAAGTAACTGAAGG CCGTCTCATCCCATGTCCACCATGTAGGGGAGGGACTTTGTTCAGGAAGAAATCCGTGTCTCCAACCACA CTATCTACCCATCACAGACCCCTTTCCTATCACTCAAGGCCCCAGCCTGGCACAAATGGATGCATACAGT TCTGTGTACTGCCAGGCATGTGGGTGTGGGTGCATGTGGGTGTTTACACACATGCCTACAGGTATGCGTG ATTGTGTGTGTGTGCATGGGTGTACAGCCACGTGTCTACCTATGTGTCTTTCTGGGAATGTGTACCATCT GTGTGCCTGCAGCTGTGTAGTGCTGGACAGTGACAACCCTTTCTCTCCAGTTCTCCACTCCAATGATAAT AGTTCACTTACACCTAAACCCAAAGGAAAAACCAGCTCTAGGTCCAATTGTTCTGCTCTAACTGATACCT CAACCTTGGGGCCAGCATCTCCCACTGCCTCCAAATATTAGTAACTATGACTGACGTCCCCAGAAGTTTC TGGGTCTACCACACTCCCCAACCCCCCACTCCTACTTCCTGAAGGGCCCTCCCAAGGCTACATCCCCACC CCACAGTTCTCCCTGAGAGAGATCAACCTCCCTGAGATCAACCAAGGCAGATGTGACAGCAAGGGCCACG GACCCCATGGCAGGGGTGGCGTCTTCATGAGGGAGGGGCCCAAAGCCCTTGTGGGCGGACCTCCCCTGAG CCTGTCTGAGGGGCCAGCCCTTAGTGCATTCAGGCTAAGGCCCCTGGGCAGGGATGCCACCCCTGCTCCT TCGGAGGACGTGCCCTCACCCCTCACTGGTCCACTGGCTTGAGACTCACCCCGTCTGCCCAGTAAAAGCC TTTCTGCAGCAGCTGA Download Select all
Length	8556
OMIM ID	138321
HGNC ID	HGNC:4555
Unigene ID	Hs.386793
Ensembl ID	ENSG00000211445
PharmGKB ID	-

mRNA Information

mRNA ID	NM_002084.3
Exon	join(1..304,4903..5056,6463..6580,6995..7094,7472..8556)
mRNA Sequence	>2878 GTCGCCCCGGGACGGGGAGGTGGGGAGCTGAGGGCAAGTCGCGCCCGCCCCTGAAATCCCAGCC GCCTAGCGATTGGCTGCAAGGGTCTCGGCTTGGCCGCGGATTGGTCACACCCGAGGGCTTGAAA GGTGGCTGGGAGCGCCGGACACCTCAGACGGACGGTGGCCAGGGATCAGGCAGCGGCTCAGGCG ACCCTGAGTGTGCCCCCACCCCGCCATGGCCCGGCTGCTGCAGGCGTCCTGCCTGCTTTCCCTG CTCCTGGCCGGCTTCGTCTCGCAGAGCCGGGGACAAGAGAAGTCGAAGATGGACTGCCATGGTG GCATAAGTGGCACCATTTACGAGTACGGAGCCCTCACCATTGATGGGGAGGAGTACATCCCCTT CAAGCAGTATGCTGGCAAATACGTCCTCTTTGTCAACGTGGCCAGCTACTGAGGCCTGACGGGC CAGTACATTGAACTGAATGCACTACAGGAAGAGCTTGCACCATTCGGTCTGGTCATTCTGGGCT TTCCCTGCAACCAATTTGGAAAACAGGAACCAGGAGAGAACTCAGAGATCCTTCCTACCCTCAA GTATGTCCGACCAGGTGGAGGCTTTGTCCCTAATTTCCAGCTCTTTGAGAAAGGGGATGTCAAT GGAGAGAAAGAGCAGAAATTCTACACTTTCCTAAAGAACTCCTGTCCTCCCACCTCGGAGCTCC TGGGTACATCTGACCGCCTCTTCTGGGAACCCATGAAGGTTCACGACATCCGCTGGAACTTTGA GAAGTTCCTGGTGGGGCCAGATGGTATACCCATCATGCGCTGGCACCACCGGACCACGGTCAGC AACGTCAAGATGGACATCCTGTCCTACATGAGGCGGCAGGCAGCCCTGGGGGTCAAGAGGAAGT AACTGAAGGCCGTCTCATCCCATGTCCACCATGTAGGGGAGGGACTTTGTTCAGGAAGAAATCC GTGTCTCCAACCACACTATCTACCCATCACAGACCCCTTTCCTATCACTCAAGGCCCCAGCCTG GCACAAATGGATGCATACAGTTCTGTGTACTGCCAGGCATGTGGGTGTGGGTGCATGTGGGTGT TTACACACATGCCTACAGGTATGCGTGATTGTGTGTGTGTGCATGGGTGTACAGCCACGTGTCT ACCTATGTGTCTTTCTGGGAATGTGTACCATCTGTGTGCCTGCAGCTGTGTAGTGCTGGACAGT GACAACCCTTTCTCTCCAGTTCTCCACTCCAATGATAATAGTTCACTTACACCTAAACCCAAAG GAAAAACCAGCTCTAGGTCCAATTGTTCTGCTCTAACTGATACCTCAACCTTGGGGCCAGCATC TCCCACTGCCTCCAAATATTAGTAACTATGACTGACGTCCCCAGAAGTTTCTGGGTCTACCACA CTCCCCAACCCCCCACTCCTACTTCCTGAAGGGCCCTCCCAAGGCTACATCCCCACCCCACAGT TCTCCCTGAGAGAGATCAACCTCCCTGAGATCAACCAAGGCAGATGTGACAGCAAGGGCCACGG ACCCCATGGCAGGGGTGGCGTCTTCATGAGGGAGGGGCCCAAAGCCCTTGTGGGCGGACCTCCC CTGAGCCTGTCTGAGGGGCCAGCCCTTAGTGCATTCAGGCTAAGGCCCCTGGGCAGGGATGCCA CCCCTGCTCCTTCGGAGGACGTGCCCTCACCCCTCACTGGTCCACTGGCTTGAGACTCACCCCG TCTGCCCAGTAAAAGCCTTTCTGCAGCAGCTGAAAAAAAAAAAAAAAAAAA Download Select all
Length	1779

CDS Information

Location	join(218..304,4903..5056,6463..6580,6995..7094,7472..7693)
CDS Sequence	>gi\|89903006:218-898 Homo sapiens glutathione peroxidase 3 (plasma) (GPX3), mRNA ATGGCCCGGCTGCTGCAGGCGTCCTGCCTGCTTTCCCTGCTCCTGGCCGGCTTCGTCTCGCAGAGCCGGG GACAAGAGAAGTCGAAGATGGACTGCCATGGTGGCATAAGTGGCACCATTTACGAGTACGGAGCCCTCAC CATTGATGGGGAGGAGTACATCCCCTTCAAGCAGTATGCTGGCAAATACGTCCTCTTTGTCAACGTGGCC AGCTACTGAGGCCTGACGGGCCAGTACATTGAACTGAATGCACTACAGGAAGAGCTTGCACCATTCGGTC TGGTCATTCTGGGCTTTCCCTGCAACCAATTTGGAAAACAGGAACCAGGAGAGAACTCAGAGATCCTTCC TACCCTCAAGTATGTCCGACCAGGTGGAGGCTTTGTCCCTAATTTCCAGCTCTTTGAGAAAGGGGATGTC AATGGAGAGAAAGAGCAGAAATTCTACACTTTCCTAAAGAACTCCTGTCCTCCCACCTCGGAGCTCCTGG GTACATCTGACCGCCTCTTCTGGGAACCCATGAAGGTTCACGACATCCGCTGGAACTTTGAGAAGTTCCT GGTGGGGCCAGATGGTATACCCATCATGCGCTGGCACCACCGGACCACGGTCAGCAACGTCAAGATGGAC ATCCTGTCCTACATGAGGCGGCAGGCAGCCCTGGGGGTCAAGAGGAAGTAA Download Select all
CCDS ID	CCDS43389.1

Protein Information

Protein ID	NP_002075.2
Protein Name	Glutathione peroxidase 3 (plasma)
Molecular Wt. (Da)	23464
Protein Sequence	>2878 MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYAGKYV LFVNVASYUGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTLKYVRPGGGF VPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDIRWNFEKFLVGPDG IPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK Download Select all
Length	226
Uniprot ID	P15056
Ensembl Protein ID	ENSP00000288602

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

EC	1.11.1.9
Name	glutathione peroxidase GSH peroxidase selenium-glutathione peroxidase reduced glutathione peroxidase
Class	Oxidoreductases; Acting on a peroxide as acceptor; Peroxidases
Sysname	glutathione:hydrogen-peroxide oxidoreductase
Substrate	glutathione [CPD:C00051]; H2O3
Product	glutathione disulfide [CPD:C00127]; H2O
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

No matching records from HPRD source could be found.

Pathway Information

Pathway Name	Pathway ID
Arachidonic acid metabolism	hsa00590
Glutathione metabolism	hsa00480
Thyroid hormone synthesis	hsa04918

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00340	39-211	GSH_Peroxidase
cl00388	39-211	Thioredoxin_like superfamily
pfam00255	40-153	GSHPx
COG0386	37-211	BtuE
PRK10606	36-198	btuE
PLN02412	39-222	PLN02412
PTZ00256	39-212	PTZ00256
PLN02399	39-211	PLN02399
TIGR02540	41-213	gpx7
PTZ00056	37-192	PTZ00056

Ontology Information

HPRD ID	1264
Molecular Class	Enzyme: Peroxidase
Molecular Function	Protein serine/threonine kinase activity (GO:0004674)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P22352 DB00143 Glutathione SmallMoleculeDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO