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General Information

• Evidence
• Gene
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Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
17848589	2007	Cell line : - Source : Tumor Bank Network established at the Centro Nacional de Investigaciones Oncologicas (CNIO). Sample Type : - No. of Sample : - Stage : -	Antibody Microarrays,Protein Labeling and Microarray Assay,Tissue Microarray Design and Immunohistochemistry	Up-regulation	1.667	-
18425376	2008	Cell line : - Source : Chinese Academy of Science Sample Type : Mouse model No. of Sample : - Stage : -	cDNA array analysis, RT-PCR, immunohistochemistry and in vitro wound assay.	Up-regulation	-	The expression of Grb2 and genes in the Grb2-mediated pathways was significantly elevated in the metastases. Overexpression of Grb2 may contribute to tumor growth, invasiveness and metastasis. 1 Patient with advanced gastric carcinoma was taken into account and 5 points of the primary tumor (one at the center, four surrounding the tumor) and 5 metastatic lymph nodes were separately digested into single cells and then implanted into the subcutis of 10 BALB/c nude mice
21622897	2011	Cell line : SW 480, SW 620 Source : West China Hospital or Sichuan Provincial People's Hospital (Chengdu, China). Sample Type : CRC tumor and Normal tissue No. of Sample : 221 Stage : -	-	Up-regulation	-	Molecular and pathological validation demonstrated that altered expression of PGAM1, GRB2, DJ-1, ITGB3, SOD-1, and STMN1 was closely correlated with the metastatic potential of CRC.

Gene Details

Chromosome: 17; NC_000017.10 (73314157..73401790, complement)
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Gene Type	protein coding
Gene Family	SH2 domain containing
Description	The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	17
Location	17q24-q25
Start	75318076
End	75405709
Strand	-
Gene Sequence	>gi|568815581:c75405709-75318076 Homo sapiens chromosome 17, GRCh38.p2 Primary Assembly AAGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGTATTGCTGCTTCGGCGACCGGGCGGCGGC AGCGGCGGCGGCGGCTGTGGCAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTC GCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGCCGGACGCTGAGCGGAGCA GCTGCGCCACGGTGAGTACGGGAGGCTGCGCTCGGCGCCTCTCTCGTGCCTTTTCCTCTTGGCTCTACAG CGGGAGTGGGCCCCGGGGGAACCGGGACCGGCCCCGGGGTTCGCGTCGGGGCGGCGAGGCTTGGGACGTG GAGCGCAATCCCCGGGGCTCCGGACTCTACGTTTCCCCTTTTGGGGCGCTTCCTTCCTGGGGACCGTCCT CCTCCGGCTCTTGGCTCTGGGCAGTCCGGGGGAAGAGGTCGGGGTTCTCTGGCGAGGTCCCCTGCCTTCA TCGGGAGGGTTTGCACGGAAGGGGCCCGGGAAGCCCAGGCGGGCCGAACGCCGACCGAGTCAGTCTACCC GAGCCTGGCGGCGGGGGACTGGTGTGGGCTGCAGCTGTGGTGATTGATGTGCCTTCGACCTGCACGGCAA CCACGTCACCATCTCCTGGCGTCTTTGGGCTTAATTTTGTGCGGGAATCCACTTTGGGGTGGAACGTTTG CTGCTGGAGCCGGGGGAGATACCTTTATTCTGACACTTAAAAAAAAAAACTATTTGAAAAATATTTGTCA AGAAAAATTCAGCAGTAGCAGGTTGGACTGCACCGAGGAAGGATTGCGGCGAGAGCGGGCGCTGGTAATT TTCATTTGCAGCGCGCCCTCTCTATGATTGTAAGCCACACATGAGTTATGGCTTGTTTAGAAAGTTTTTC AAGGCTGGCTTCAAACGCTGTGAAAGTGCAGTTTGCAGGGGACTGAAGTGCACTTGAGGTCTGTCTCTTT TTGATGCTGTTGACTTTCCGAAATGTCAGACACATGAGAGAAATTAGCATTAGTCTATTTTGGCTTTCTT ACTCCTCTTTCTCCAGTTATTTCCTTCCTTCTCTATCTGCTTCTGTCCTTTCCACTAGGGACACGAAATG CTTGTGTAATGCAAGTCATTTGCCCCTTCCTCCCCCCACCCCCCCCTTTTTTTCTAATGTACTTCCCCTT CCTCCTTGTAGTCCCCACTCTGGCGTAATTTTTCGAGGTTTCTTCCCTTTCGTGCTGTTCGTTTTCTCTC ATTTCAAGATTCCGTCTTTTTCCTCGGGAAGAGACTCTCTTTCCTTGCTTTCGTTCCTTTACTTTTGCGC GTCCCCTGCGTTCCCTGCAGTCAGCCAGAAGGGTTGCTAGAGAGCCGTGGGAGGCTGAAGTCCCCTCTCT GAGAACGGGGAGGCTCAAAAGATTGAATTCATCCCTAAGAAATCAGTCCTGCCACTAGGTCGCAAGTGTG GTTTGCTTGTATTATTTTTGTCTTTTACTCTTTTTCTTTTAAGATTATGCTTCTGTGCCTGCTTATGTTT TCTTCTAGTATGTCTTTATAATAGGAAGATTGGGTCAGCTCAGTGACTTTTTTTTTTTAGGCAGAGTTTT GCTCTTTTTGCCCAGGCTGGAGTGCAATGGTGCTATATGGGCTCACTGCAACTCTGCCTCCTGGGTTCAA GCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATCACAGGCGCCCACCACCATGTCCAGCGAATTTT GTATTTTTAGTAGAGATGGGGTTTCACTGTGTTGCCCAGGTTGGTCTTGAACTCTTGACCTCAGGTAATC CACCCGCCTTGGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAGAGTTAATTCT TATAATCAGCTTTCTTCTACTAAACACAAGCATTTATTTATTTATTTTATTTTTTTGAGACGGAGTCTCG CTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAGCTTCCACCTCCTGGGTTTAAG CGATTCTCCTGCCTCGCACTCCCGAGTAGCTGGGATTACAGGTGCTCACCACCACACCTGGCTAATTTTT GTATTTTTGTAAAGACAGAGTTTCACCATGTTGGCCAGGCTGGTCTCGAATTCCTGACCTCAAGTGATCT GCCCATCTCAGCCTTGGGATTACAGACATGAGCCACTGCGCCCGGCCTGAACTCAAACGTTTAAATGTTT GAGGCACTTTACTTCGTCAGCAAGTTATTCAGATTTGAGAGGCTTGCTGGGTTTTAAATACTACTGGTTG ATGGTACTTAGAGATTCTTCTCAGTAATTGCTGTTATCATGTTGCATGTTGTCCATCAGAGTTCTAATTG TTACACATACAACAGAAGAGGAATGGATTTTGGAGAAATGAAGTAATACAGAATAGAGAGTCACCATGCC CTCCGGAGAGAAATTAATACTTGCTTAATTCAGAGGAACTCTCCACCATTACTGAATGGCTTTTGAGAGT CTGTATATATATATATATTTATATATATATATATTTTTTTTGGTCAAAGTTGCCTTTTTCCTAGTTGTGC CAAGTGAATACGCATTATTTTCTTTTTCCTTTTTTTTTTTTTTTGAGACAGATTCTCGCTCTTGTTGCCC AGGCTAGAGTGCAGTGGCACGATCTCAGGTCACCACAACTTCCACCTCCTGGGTTCGGGCAATTCTTCTG CCTCAGCCTCGCTAGTAGCTGGGATCACAGGCATGCACCACCACGCCTGGCTAATTGTGTATTTTTAGTA GAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTCTGGAACTCCCGACTTCAGGTGATCCACTCACCTCAG CCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAATATGCATTATTTTCATTTCATG CAAGGACATTGTAGTGCATTATCTGGAATGCAAATTTTAAAATCTGGTTAAGGCATCCTTATGGTATAGC AGTTATTTAAAATTTAGTATCCATAAAAATCACTGGGAGATCTTTTTAAAATTAGGTTCTGGTAGAACTC CAGGATGTACCCCACAGTGAATCAGTCTCTGAATGGGTGGATTTTGATACAGATGGTCTAAGGATCAAAA CTGTTGTTACCAAATGCAGCCATAAATAATAAGACTGCTGTGTGGCTTTAAGTAATTCAACTTAAAATTA CATTTTTCTGTGTATACACAAAGTCAGTATTTAGAATAGCCTAATGGAATGAGTGACTATAAGCATGATT CATTTTTACATGTGTAAATTTTTTAGCATTCTTAATACTGTGATGTGGAGTGATTTAACTTGAAATTTAT ACTTAATAGGGTCATTAATTTGCCTACCAGAGAATTCTTCTGAGTCTGTAGACTCAGACGAAAGATTTTT CAGCTTTACAGTGGTGTGAAAGCAATAGCGCTCAGTAAAAACTATACTTCCAGTACCCATATAACTGTTT TGTTTTTCACTCTCAGTACCATAGTCAGTAAATTACAGGAGATATTCATCACTTTGTTATAAAATGGGCT TTGTGTTAGATGATTTTGCTTAACTGTAGGCTAATGTGTTTGGAGCACATTTAAGGTAAGGTAGGCTAGG CTAAGCTGTGGTGTTTGGTAGGTTAGGTGTATTAAAATGCATTTCCATGTAACAATATTTTCAACTGATG ATGGTTTCATCAGGATATCTGCCTATGCAGATGGAAGCTCCACATTTACTCTTAGAACATGTAGGCTAGT ATTTGAAAAGAGACTGAAAATACTAGTTAAGGTCTCTGGCTTATACTACATTATAATAATAAAATCATCA CAGCCCACACTATAGTGGATAATTAGTTAGCTCAGTCTTTTGGAGAGAGCCAGAGACTTCTGCCAAGCAT TTTACAACCATTATCTCTTTTAATTATCAAAATGACTTTATAAGGTAGTTGGCTGTTATTATTCCCATTT TCCAGTTAAGGGATACTAGGGATTACAGAGTATAAGTTACTTCTCCAGTGTCCCCTCATTAGTAAGTGGA AAGTGACATTTGAATCCAAGTCTAACTCCAGAGCGTCAGTAAGCTTTTTGGTTTGTGTTGTAACTACAAA AGTAACACATGCCTATTGTAAAAATAATGAAAATACAATTGAGGTGTATCATGCAGAAAGTAAAAGTGTT CTGTGATCTCGCTAGCAGAGATAACCATTGTTAGCCTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCT CGCTCTGTCGCCCAGGCCGGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCTTCCC GGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCGCGCCCGG CTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGATCTCCTGACC TCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCTAGC CTTTTTTTTTAAGCACATACTGATGTATTATTTTGCCTTACAGAAATAGGATAAACTATAATTTTTCTGC AGCTTTAAAAATTTGAGGAGAATGGCTTGAACCCGGGAGGTGGAGGTTGCTTTGAGCAGAGATCATACCA CTGCACTCTAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAATTGATATATCCTGGTA TTTATGTAGATACTCCATACACAAGCTCATGGATATTGATCAAGGGTGTGGGTGTATATGTGTATGTTGC ACATTGTATTTTGTCTCATTGTTTCAGTGAGATAAATCTGGGAAGTGGAATTGCTTGGTCAAGAGTATGT ATTGGTCAGGCACAGTAGCTCACGCCTGTCACCCTGGAACTTTGGGAGGCCGAGGTGGGCGGATCACTTG AGGTTGGAGACCAGCCTGGCCAACATGGTGAAACCTCGTCTTTATTTGAAAATACAAACATTAAAAACAC ACACAAACACACAAAAAAAGAAAATTCAAAAATTAGGTGGTGGTGACACGCCTGGAATCCCAGCTACTTG GGAGGCTGAGGCAAGGAGAATCGCTTGAACGCAGGAGGTGGAGGTTACAGTGAGATGAGATCACACCACT GCATTCCAGCCTGGGCAACAGAGCGAGACTCTGTCTCAGAAAGAAAAAAGGAGCATGAGGCTGGGTATGG TGGTATGCATGTAATCCCAGCACTTTGGGAGGCCAAGGCTGGTGGATTGCCTGAAGTCAGGAGTTTGAGA CCAGCCTGGCCAACCTAGTGAAAGCCCATCTCTACTAACAGTACAAAAATTAGCCAGGCATGGTGGTGCA CGCCTATAGTCCCAGTTACTTGGGAGGCTGAGGCAGGGGAATTGCTGGAACTCAGGAGGCGGAGATTGCA GTGAGCTGAGATCGTGCCATTGCACTTCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAGGAGT ATGTATTTACAAAAATTAGCCAGGTGTGGTGGCACACACCTGTAGTCCCAGCTACTTGGGAAGCTGAGGC GGGAGGATGGCCTGAGCCTGGGAGGTCAAGGCTGCAGTGAGCCAAGATGGCACCCACTGCACTCCAGACT GGGTGACAGAGCAAGACCCTGTCTCAAAAAAAAAAAGAGTATGTATTAATATTTCAAAATTGTCGGTCAG GGCCGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCGGATCACGAGGTC AGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCATGTCTCTACTAAAAATACAAAAAAATAAGCCG GGTGTGGTGGTGGGCACCTATAGTCCCAGCCACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCTGGG AGACGGAGCTTGCAGCGAGCCAAGATTGCGTCACTACACCAGCCTGGGCGACAGAGCGAGACTCTGTCTC AAAAAAATAAATAAATAATTGTTGGTCGGGCGCGGTGGCTCACGGCCTGTAATCCCAGCACTTTGGGAGG CCAAGGCGGGTGGATCACGAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGTGAAACCCTGCCTCTA CTAAAAATACAAAAGTTAGTCAGTCGTGGTGGTGGGGGCATGTAATCCCAGCTACTTGGGAGGCTGAGGC AGGAGAATGGCTTGAATCCAGGAGACAGAGGTTGTGGTGAGCCAAGATCGTGCCACTGCATTCCAGCCTG GGTGACAAAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAAGAAAAGATTGTCAAGGCCAGGTGTGGTG GCTCACCCCTGTAATCCCAGCACTTGGAAAGGCTGAGATGGGGAGGATCACGTGAGTCCAGGAGTTTGAG ATCAGCTTGGGCAACATGGTGAGTCCTGGTCACCACACACACACACACACAAAAATTAGCCAGGCATGGT GGTGTGCACCTGTAGTCCCAGCTACTTGGGAGGCTAAGGCAGGAGGATGGCTTGAGCCAAGGAGTTTGAG GCTGAAGTGAACCATGATTGCTCCACTGCACTTCAGCCTGGGCAATAGAGCGAGACTCTGTCTCAAATAA TAAAAGTAAATAGGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGGCAAAGTGGGCG GATCACCTGAGGTCGGGAGTTCAAGACCATCCTGGGCAACATGGCGAAATCCTGTCTCTATTAAAAATAG AAAAATCAGCTGGTCATGGTTACAGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCG CTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCGGAGATCACGCCACTGCACTCCAGCCTGAGGGATAGAG CAAGACTCTGTCTCCAAAAAATAAATAAAAATAAATAAAAGTTGTCAATAGATTACCAAAGAACTCACCA AAAAGATTGAGCTGAGCTCATTAATTCCTTGCTGTAGTGTGGGTTCTGTGGTGATTTTATTATTATAATG TAACACCAAGCCACATTGTCAGTTAGTAACTTCTCAAAATGTTGAGTCAGTGGACACCGGGTAGGGTAAA AAGTCTTTGTGCCTGGTGCGGTGGCTCATACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCAGAT CTGTTGAGCTTAGGAGTTTGAGACCAGCCTGGGCAGCATAGGGAGACCCCATCTCTACAAAAAAAAATGA GTAGGCTATGGTGGCTGGTGCCTGTAGTCCCCACTAAGGAGGCTGAGGTGAGAGGATCCCTTGAGCCCAG GAGGCGGAGGTTGCAGTAAACCAAGATCACGCCACTGCCCTCCAGCCTTTGCTACAGAGTGAGACCCTTT CTGAAAAATAAATAAATAAATAAAAGTGTGTTTACTCAAAGTATTGCAGATTGGATTTTATAAATATTTT TAAAATTTGCCAATTAGTATATGAAAACTCTGATTGTTTTAATTTGCATTTCTTTTCATATGTTTTAAAT AGAGTAACATTTAAAATTTCTTTTGAAGGCTGGGTGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGG AGGCTGAGGTGGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCCATCTCTACTAAAAATGCAAAA GTTAGCCAGGCTTGGTGGCGCGCACCTGTAGTCCCAGCTACTTGGGAGGTCGAGGCAGGAGAATTGCTTG ATCCTAGGAGGCGGAGGTTGCAGTGACCTGAGATCGTGACACTGCAGTCCAGCCTGGGCGACAGAGCTAG ATGCTGTCTCAAAAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATTTTGAGTGATTATTACA TGTCGGGCTCTATCCAGAGCACTTAATGTATGTTATATATGTTGTCTAATTTAATCCTCAGTGGATCTTA TAAGGTAGATATTCTCATTTTACAGATGAGAAAACTGGAGCTTGTTTCACAACTTTGCCCACAACTGTAG CTGTAAGTGTGAGGGGCCTGCCTCTAGAGACCATGAAGATTCAACACTAAGCTATACTGGACTGTTGTCA TGTATTTTATTTTCTGTGAATTTTGGGAAGAAGAGAGTTAAATGGAAGAAAGAAAAAAAATCTTGCAAAT ACCTTTAGGATAGTAGTTTTTTTGGATACAGTAGACATTGTTTGAAATGAATGATTAAAGCTGTACTTAC CTTTCTTAAAATTCACTGCTTGGGATGGGCTGGTAACAGTTTCGAGGTTACTCTCATTAGGCTTCAGTGT TAAGTACACTATACCCCATTTTCTTGGGAAGTGAACAGCAACATCTACTCTGTTAAAATCATTATACATT GTGTCTGCTTTCAGATTTCTTCCTTTTAGTAATTAGTGTTGTGTATGTGTTAGATTTTTTTTTGTCTTTA CTGAAACACACCCTTTGGAATTCCTTTAGCGAATATGCTCTTTTGGGTGGATAACCTAATAAGCTTTCCT CTTTGAGTTTTCTGTTTTTTTACTCAGCACAGCCATGGAAGTAGGGATTTAATTTTCTGTCAAACTCTGC ATCTCACAAAGCAATAGTTACTCAAAACACGACTTTCAAGAAGGTTATTCTTTTTAAGCTTTCAGCAGAT GAGCTGAGTAGCAGCAGGAAAGCAGGTATTGAGAACTGTCTTGGTTTTTGTACTGCTGTTGAGTAGTAAC ATTGCAGCTGTCTTAAATCCTGAATGACACAGAAGCTTATGGCTGGTCGTACTACATAGCACCTTGAAAG TGACAGGGCTTTTCATTTCTATCTGATTTCTGTTTTTCAAAAATAAAACTCCTTATTCTTTTCCTATCAT TGTAAATATTCTTCAGCTTCCTATCACTAATACATAGTCTCGGCATTAGAGACCAGTTAAAATAAATAGG CTGAGGAAAATCTTGATAGTAGGAGAGATTTTGGAGCATTCATTAAAAGTAAAAATAGGGCTGGGCGTGG TGGCTCACTCTCCCCTGTATTCCTAGCACTTTGGGAGGCCGAGGCAGGCAGATTGCTTGAGGCCAGGAGT TTGAGACCAGCCTGGGTCTTAAAAGGTAGATATTATTCTCATTTTACAGATGACGAAACTGGAGCTTGTT TGAAAAGTTTGCCCAAAATTGTAGCAGTTAGCGTGAGGGGCCTGCCTCTAGAGACCATGCAAATTCAACA CTAAGCTATACTGGACTGGTCTCACATAGTGAGACCCTGTCTCTACAAAAAATAGAAAAAGTAGCCGGGC ATAGTGGCCCACACCTGTAGTTCCAGCTACTTGGGAAGCTGAGGCATGAGGATTACTTGAGCCAAGGAGA TCAAGGATGCAGTAAGCCATGACCATGCCACTGCACTCGTGCCTGGACAACAGTGCAAGACCCTGTCTCA AAAAAAAAGAGAAAAGAAAAAGTAAAAGTAGATACACAGGGAACTAGGCAAGTAAAAAATAGAACATTAA GCAGTTGCTAATGCTGGGAAAAATCTAAGGATTGTACAAAAAAGTATGATTGGGTCAGGCACAGCGGCCG ATGCCTGTAATCCCAGCACTTGGGGAGGCCAAAGTGGGCGGATCACTTGAGGCCAGGAGTTCAAGACCAG CCTGGCCAACATGGTGAAATCCCGTCTCTACTAAAAATATAAAAAGTAGCCAGGCTTGTTGGCACATGCC TGTAGTCCCAGCTACAGGCCGAGGTAGGAGGATCGCTTGAACCTGGGAGGTGGAGGTTGCAATGAGCCGA GATCATGCCACTGCACTCTAGCCTGGGCAATCTTAGAGAACTCTATCTCAAAAAAGAAAAAAAAAAAAAC ACAAAAAGTATGATTGGTTTTAGTGCATTATTTAAATTATCAGTGAGTAGTATTTCATAACATACTACTG ATTAAACCAGAATATGTGATATTACTGGTATAGGTCGGGGGAAACTAAATCTTCACCTTTCAGGCAATAG ATAATGGCTGGAATAAACTGAGAAAGCAGTAAAAGCACATTCTTTAGAAATACTCTATCCATTTTGTGCA TTGACCACAAGATTTAAAAAAAGAAAAATAAGTAAATACAAAGAGAAAGCAAAAAACAAAATCGAGAGTG ATCGCCTGTGGGTGTTGGTAGGGAGCTGCTCTTTTTCATAAGCCTTTTAATACTCTGACTTTTAAAATTA TGTACACGGATTAGTTTGATCAAAGTAACTACAGAGAGTGTAAGTGAAGGGCATTTAAGGATACACAAGT ATAAATATTCGCAGATCAACCTCTGTATTTTTTAATATTTGCTGGGACTCTTTCTTTACTTTCCCTGTTA CAGCCAGCGCCACATGGAATATCTTAGGTATGGCCTGAAGGAATAAACATTGGTTTGGTTTATTAGTTAC CTGCAGCAGAATGTTTGGCTTTCAGAATTTGACTGAAGGACTCATTGTCAGACGATTTATTTTCTTTTTG ATAATACTTATCTTGGTCTAATCTTAATATTCCCCACTGCTTTACTACTTGGTCCATTTGCAGCTATGCT TGATTAGTGCCCCAATTGTCAACTTTAGAACAAAGGAATAATAATCACTTGTGCCCCTCAAATGAGCTGC TGGGTTGTAATTATCCAAGAAAGGTGTCACTATAAATAATCTGTCCCAGTTCTGTTGTTTTCTGCTTTTG TTTAGCAAGTATGAAAACAGTGACCGAGCTAACCAGAACGGGGCTTTATTTTTATTTAGTTATCCACAGA TCTAGGTTGTGTCCTATATTCATGGCTGGAGACGCTTCACTACACCGTTCATTGTACTACTGCCAGTTCC TCATCGTCTGATACAGTATCTCAGGGTTCTCACAGAATCTTTTACCTGCAAAATGCAGTTTGCATCAGTT TTATACTCTGCTTGCTCTAAGAAGCTGTGCACAGGGTGACTGTGAGAGAGACTTCTCTTTGACCTTCTGC GGGCACCATCTCCCTGCACTTTCTTTCCCAAACAAGATACTTGGCAGCTCAGATTCTGAAAAAGGGATTC CTTTCAAGTGTAGATTAGGACTTCAGCTCTGCTCCTTAGGTTAGTTAGAAATAATGTGGAGCTATTTCTG GAGTGCTGAGCCTTGGTCATTTATTTCATTCCTGGTGGGGACCCCAGAGTCTTGGGGATCTGCCGGGGAA AGGGAGCCTTATGCAAGAGCGTCATCCCCACCATTTCCACTGGTACACAGCTTGGAGCTGTGATCTTTCT CTGGTTACCTGAGCTTGCCGATCACAACATGGAAGTGCAGGGGGAAAGCCGCCGGTGCTTGTAGCAGTAA ATGGATTGAAAAAGCAGTTCCTACATTTACTTTCTCCTGCTCTCCTGGGAGCAGATCATGGTTTAGTTTC GAGAAGAGTGCAGCAGCTCGAGACCAAAGAGTTTTGCTTTGCTTGCTCTTGACTGTGCAGTAGGGAAGCC AGCATTCTCAGAAGACCAGAAAGGATGGCGGTGGGGAAGGGAGGGAGACAGGCCTGTTTAACCGAGAAGA GACAGGTGCCATCCCCAGGGTGAGGCCTTCCTTTCAGTGGACCGTATTTGGTGCTGGAGAAGAGCCTGTG AGGAGTAAAGGAGGAAAGGCGGAGACTGAGTGGGACTCCAGCCGGTTCCTGCACGCAGTGCACACCCAGC GGGAAGGAAGAGGAAGTGTGTTCAGGAATAGCTCAGGCAGCTGTGCCATTGGCCGGCAGGCCTGTCAGTC GCCTGGGGGCCGAGGCTGAAAAGAGGAAGAAGTCGGCGGGGGGGGGCTGTTGCCTGGAAGGGAGGGAGGA GGGCTGAGCCAGGCCGAGCCAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGGCGGGGTTGCC TTCAATCCTGGCCACTGCTCTTAATCGTCCCTCTCCTGCTTCAGGGTGGCATTGTGTGTCCCAGAGTGCC GGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCT TCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAA AGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGTAAGTGCTGATGCCGAGCAC AATGCTGAGATCGCTCTCCCTGTGCTCACCCACCTTCTTTCGCCCTGATTACACACAAAGAAGCTGTGTT TTTCATTGTACACTTTTAACATTTACCATCATATTTGTTCTGGAGAGCTTTAGATGCTGAGTAGAATATT AAATATGACTTAAGTGAGTTGGTGTGATGTGTGGTGTTTAACTGCCTTTGTGTGAATGCCTCATTTGTCT GTTGATACTGGTAATATTTCAAGTAAAGTCAAAGTAATGTGATTGTAGAAAGGAAGTATATGAGTAGATT GATTTGCCCTGTAGAGTTTTATTTTAAAAATAGCATTTTTTAAAAAGACCCAGACCTGAAGTATTTATGT AAAAGCATTCAGTTAGTCTTACTTTGTATAGCCAAAGGATTTTGCGTTCTGGAATATGATTTTGGTAGGT TAGAAATTAATTTTCCCAGTTTAGAGAGGTTGTTAGAAGTACATACCAAAACTCATTAAAGAACTTCAGT GTATTTTTATTCTTTGTGAAAAAACAAATGGAGTTCTAAATAATAAGGTGCAACCTGCTATTGTACAAGT CAGATTTCGACTTTCTTAAAAGAAACTTGAGGAGCAATTACCCCATATTAAACTCTAATTGCACGAAAAG AAACCTGCTGACAGTTTAAAAATCAGCTTCTATACCATGTGCAGCTTATTTTGAGCCCCACTATTTATGT GAGGATTCGCTCTCCCCCAGCACATGTTAATTATGTTGTTTACCCAATTGACTGTAGCAGTTTGCTCTTT TGGATGTGTAATTTATTTTAACGAGGATGAGTGTTATCAAAGAGTATGTTAACTTTAAAGGAGGAAAGGC TGAAGCTTCATGTTTGAGTGTTCCCTGTGTCTCAAGTTTTGACATTTTTCCTTCTGAGCCTTAGACTGAT TGTTGGAATTTGCTACCTCATTTGTTTACTACCCCTGAATGAAATTCTTAGAATTTTATGAAGAGAAAGC AAGTGGAGATGTAGAAATATGGTTCTTTATAAAAGGACGTGCAGTCTTTTTACTTTTAAGTTATGTGGAC TTATTGATAGTCTTTATTTTGCCCTCATTGCCCAAGGCGTAGAGTTCTACTCTGAAGTTAACTGCCCAGT AATTTCTTAATGTTAGAAATGTAGGTTGAGCCTCATAGAAGATGATGCTGCAGAGCCCTTTAAAGAGAAG AAAACTTTGTGTCTGTGTGTTCATTTCAAAGCTGTGTTTGTGACACCACACTTTTCGAGGGTATTCTCAA AGTCAACACTAAATTGTCAGAAAGCAGACGGAACCATTTTCTAGAAACTAGGTTTCTATTTTCTTGAACT AGAGAAAATATGCCCAGCTAGAGATCAGGGCAAAGTTAACTTAGACTACAAAATTCCTCAGTTTTCATTG GTGTATGGGAGAGGTAATTTGATGTTTCTGTAGGTGATTACTGTTTTCTGTAGATAACCCACTTGTGATG GTATAAGATGGGCTACTCAAATGCCCACATCTATAGCCTGTACAAAAGCCCTTTTGGGCTAGTATTTTTT GTTTTTGATACAAACTTAGATTTTTTCATAAGTTTATCTTAGAAACTTGAACCTAGAAGGCTGGTGGTTC ATATTTTTCTCTAAATCTGTCCCATTGCACATTAAGCACTGAAGCAACAAATTAAAACAAAACTAGGGGC ATGCGGTCTCTTTTTAAGAATTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGG CTGGAGTGCGGTGGTACAATCTGGGCTCACCGCAAGCTCCACCTCCCAGGTTCATGCCATTCTCCTGCCT CAGCCTCCCGAGTAGCCGGGACTACAGGCGCCCGCCACCACGCCCGGCTAATTTTTTGAATTTTTAGTGG AGATGGGATTTCACCATGTTAGCCAGGATGATCTCAATCTCCTGACCTCGTGATCTGCCCACCTCGGCCT CCCAAAGTGCTGGGATTACAGGCGTGAGCTACTGCACCCAGCCTTTTTTTAAAATTTTTAAACAAGAACT TTCCCTGATTTCTGTCTTTGAAGTTTGTCCTAGACCTAGACCATGAACATTTTATAAATTCTTTAACTTA AATTAGTAAATTCTGGAGCAAGTGTAAAAACCTTCTTTCCCATCCTATTATTAGGGAAGAAGATCCTGTT TAACAGTCCCTCAGAAATTTTTATTATGGAGGAGAAAGTAAATCAGAATACTCACATTCACTTTTAGATT TTCTTTGAGGAGAGAGAAAAATACATATATGTGGTTCTTTTCAATTTGGTAGATAACTGAGATATGAAGT CATAATGCCATTATTGCTTTTGAACGGTGGCCATTAGCTGTTTGTTGGTAATGTTGTGGCTTTACTCCAA AAGAAAAAAAAAAGAGTGACGATACAGTAGTTGCCCTTTGTCTCATAACTGTGTGAAATGGCTGGGTGAA GAGGAGGAACATGCTTTCTTAAAAGCTGTTAGTTAAAAAAACGGAGTTTTCCTCATTTGATTCTTCAAGA AGTAAACTGGCTTCATTTGAATTGCTTTGATTTGGGACGTCTTGAGGGTATTAGTTGTAAGCCAAAACAT GTTTTAAAAGTTGCTGGAATAGCATTGAACAATTTAACTTTCATTGAAATAGGCATATATATGCCTTCTC TTGATAAAGGAGACGTGCATATGGATATTGAATAAGTTTCATTTCAAGATAATGAAATAGGCACTTAGCC TTCATCCTCTGTCTATAGTTCAGAAGGATCACATCTTCTCCTGTCTTGGAGTTCCTGGTTAACTTTTAGT TAAAAATGGTGACTCCTCTCCTCCAGCAGACCCCTTCCCTACTTTCTGTCTACACATTGACCTGTTACTG TCCAGAGAAAAAGAGGAAAAAATAAAAGCATTTTACTGGAAGCCTAAAATAGAGTTGAATGGTTCAATAT GTCTGCCTTTGTTTCTCTCTCTTATAAAAGCTTGTGTTTTTCTTGGCTCGGGGAGGGAGAGGACACTGGG ATGTAAAATAGAAGGAATTGCCCTTCCACTGCAGGTTTCAGGCCTGGTGTGGTTGGAATACATCAGAATT CCTCCCACCATTGTAGGGCAGGCTTGAGACAGTCCCAGAGGTTCTCCACTGACAAGACCCCTAAATAGTC TACACTAGAGCACATAAAACTTACCTAGGAGTTGCAACTGCCATTTAGGGGCTTATGTATACATACTTCA AACTGTGCTTATAGGAATTAAGAGACCCATTTTGAGCTCTCAGATCTGTGCTCATTCCATTCTAGAGCCA GCCTCTTGCTTTCTTCAGCTCTAGTGGAGAGCCAGCCTGGATCATCTAGGTGTATTCTACCCTCTCTGGC ACTAACTACCTTTACCAGTTTCTTAAACTACTTTAAAAACAGGTCTTGAGTTCACATTGAGATCTTCAAA GCATTCTGTCTCAGCACTGCCTGGCCTATTTCAGTGTCACACTGACTGAGCATCTCTTGAGCCAGATACT GGGATAAGTTGCTTTGAGAGTTGGGAGAGAAATATAAGATGTACTTTCTCCCTTCAGAAGCTCCAAAATC TCAAGTAAGAGAATTGAGATTAATATGTGAAACAGTACAAGATGGTATATAAAAATTTTTTTAGAACAGG AAAAGATCTTTTAAAATTTATTTTTATTTATTTTTTTATTTTTTTGAGATGGAGTCTCGCTCTGTCACCC AGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCTGCCTCCCGGGTTCACGCCATTCTCCTG CCTCAGCCTCCCAGTAGCTGGGACTACAGGCACCCACCAGCACGCCCGGCTAATTTTTTGTATTTTTAGT AGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTGGTGATCCGCCCGTCTCGGC CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCAAGATCTTTTAAAATTTCTTAAGTTA GACTTACTCTTTTACAGATGAGGAAATGGTGGCCCATATAGGTTAAATGATCTATCCAAGATCACACAAC TATCATTCTTGGTAGTGATTTGTAGTAGTGATTCTTAGTAGTATTTGATGGTATACTTGAGTCGGGTTGC ACACTGTAACTGCTAGAGTCGTTCAGGAAGGATGAAACTGGCAAGCGCTGACATCAGTCAGGTGTGTGCA GAGTTGTGACTTGAACCTTGTAGGAGAACAGGACGTGTAGGTTAAGAGAAGGAGGACATTTCAAGGGAGA CGAAACTTGTGCTTGTTGTGTTTGAGATAGGAAGGCTGGAATAAGAATCTAGACTGACATAGTGGAAAAT AAGGTAGAGTTGGAGCGAGGTGAGAAAAGCCCAGTAAGAGTTTGATCTGGTCCTTAAGAAGCCTCGGAAG GTTTTTAGCGATGAAGAGCATTGTGTGTGTGTGTATAAAGAATTGCAAGGGGGCAAGGCTGGGGCCCCAA GCCTGGATGGTGGCAAGTAATCGGGTTGTGTGTCAAGTGTCTGTATCAACCTGGGATACTAGAAATGAAG GAGGGGAGTGGTTTGAAAGATACTGAAAGCAAGAATCATGGGATTTCTGCCTGTCAGATAGGGGCATTTT AATAAGTCTCCTAAGAAAGGAATGCCCTTTGATTATGATCCTCAATGGAGAAGATCAGTGGAGAGCCAAT CCCTAGTTTGGTTGGTTAGAGTTTTCACAAGTTATAAGTCCTGAGTTTCAGTGCACAAGTCCCATTTCAG GGGTTCAAATTACCTAATCTAAATAAAAAGCCAGGCATGCTCGTGCAAGCCTGAAGGCCCCACCTGCTCA TGAAGCTGAGAGAGGAAGATTGCTTGAGCCCAGGAGTTGGAGCCCAACCTGGGCAACAAAGCGAGACCCC ATCTCCAAATTAAAAAAAAAAAAAAGTGTTTTTCTTCCCCCCCCCCACTATTTTAAAGTCCTAGTATCAG TATACTCTGTAGAACCATTTATTTTTTCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCATTGCACCCA GCCTTTGCCTTTTGGTAAGAATTCTTATCAATCTTGTTGACTAAACCAGAATATTGCATTTAATCTTTAA GAAGGAGGTTAGTTTGTGGTCAGGCGTGGTGGCTCACGCCTGAATCCCAACACTTTGGGGAGGCCGAGGC GCATGGATCATTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAA AATACAAAAAACAGCCGGGCCCGGTGGTGCGCGTGCGTACCTGTAATCCCAGCTACTCGGGAGGCTGAGG GAGGAGAATCGCTTGAACCCGGGATGTGGAGGTTCCAGTGAGCCAAGATTGTGCCATTCCACTCCAGCCT GGGCAACCGAGAGAGACTCCATCTCAAAAAAACAAAAACAAAAAAGGAAGGGAGCAGTTTGTTGTTTGAG TGCTCTTAAAGCAAATAATCTGCTTGCTTTTTATTATATTCATTTTGTCAGCTGAATGGACTATTTCCAA ATAGGTGCTGAGAATGAACTTTCATTTCCTATAAAAGATTCTTTTTGGGAGACTGGCTGAAGATGATTCT TCCTCCTGTTTGGAGAAAGAAATGAGTAAGGAAATGTAGTATTCCTTCAGAATCTTTCAGTTTCACCTCT AAACCATATGGTAGAATTGCTTCTAAGTTGTTGGGTTTGTTTTTTTGTTTTGTTTTTTTTTTTAGGCGAA GTCTCACTCTGTCGCCCAGGCTGGAGTGCAATCGCACGATCTTGGCTTGCTGCAACCTCCACCTCCTGAG TTCAAGTGATCGTCCTGTCTCAGCCTCCCGAGTAGATGGGATTATAGGCGCCCGCCACCACACCTGGCTA ATTTTTTGTATTTTTAATAGAGATGTGGTTTTATCATGTTGGCCAGGCTGGTCTTAAACTCCTGACCTCA AATGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCCAGCCTACTA AATTATAGATCATTTCTAATCTTGAATGCTGAAATATTGACTTTTTTTTTTTTTTTTTAAGACAGAGTCT CCCCCTGTCACCAAGGCTGGAATGCAGAGGTGCCATCATAGCTCACTGCAACCTCTGCCTCCCAGGCTCA AACGATCCTCCCACCTCAGCCTATAGCTGGGACTACAGGCACGTGCTACCACACCCTGCTAATTTTTGTA CTTTTAGTAGAGGTGAGTTTCACCATGTTGGCCAGGTTAGTCTCGAACTCCTGGCCTCAAAATATCTACC CACCTTGGCTAGGATTACAGGCTTGAGCCACCGTCCTGGGCAAGATTGGCACTCTTTTTTTTTTTGAGAT GGAGTCTCGCTCTGTCCCTCAGGCTGGATGGAGTGCAGTGGTGGGATCTCAGCTCACTGCAAGCTCCGCC TCCTGGGTTCATGCCATTCTCCTACCTCAGCCTCCCGATTAGTTGGGACTACAGGCACCCGCCACCACAC CCAGCTAATTTTTGTGTGTGTGTGTTTTTAGTTAGCCAGGATGGTCTCTATCCTCTGACCTCGTGATCTG CCCCTCTCAGCCTCCCAAAGTGCTGGGGTTACAGGCGTGAGCCACCGCGCCTGGCCAAGATCGGCATTCT TAACCCCATTTTATGGGTGCAGAAACAGGCTCAAAGCTTAAGAAACTTGCTCAGATTCACACATCTAGCA AGTGACAGAGGTGAAGTTTGATCTTAGGTCTTGCTGTGGTGTACTGGGTGTACCCATCACAATACATGGA TACCCCTCTTAACTGTCCAGGTATGAGTAGACCAGAAATGTTAGGGTATCAGTAGTCTTGCTTTGTTCAG CTGCCTGGCATTGCTTCCATGAGTGATTTATTGGACTTCCTGTCTAGAGTAAGTTTGTCATTTTGTATGT CAGATTACCAAAGATAACAAAGATTGACCCCATCCTTTGCTGGCTACAGTGTGAAGAAATGGTTACCACT TTCCCATGTCTCTGGAGATTTTTACCAATATTGTCTTTCTCACTGGTGGCTTGGTAATAGGTATCAGAAC ATAAAATGATCCAGCAAGTAACATTTTAAGAATTTGTTCTAAGGCCAAGCGCAGTGGCTCATGCCTATAA TCCCAGCACTTTGGGAGGCCAAAGCGGGTAGATCACTTGAGGTCAGAGTTTGCGACCAGCCCGGCCAACA TGGTGAAATCCCGTTTCTACTAAAAATACACAAATTAGCTGGGCGTGGTGGTGTGTGCCTCTAGTCCCAG CTACTCAGGAGGCTGAGGCATGAGAATCGCTTGAACTCGGGAGGCAGAGGTTGCAGTGAGCCGAGATCAT GCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCCGTCTCCAAAAAAAAAAAGAATTTATTCTAAGA AACTCATAAACAAGTTTTTTAAAGATGTAGACATAAGGATGTTTATTTCAATTATGTATATACCACCTAG AAAAATTTTTTTCTGCCAATACTGTCAATTGTAAGATGCATTTTAGAGATGTTAAAACACATAAAAGTGG CATGCACCTTCCAGTTCATGAAATTGCCATACAAGCCAAAAAGCAAAACCAATTAGTGGGGTTTACAGAG GTAGATTATGGCACCTATTAAGTGGCAATGAAGGTGTTAACGTTGATCTGTATCAACACAGAATAATGCC TACACTTGCACAGAGAAACGTTTAAATGGATCCTGTTTTAATAAGTAATAATATAACTAACATATTAAAT ACTTAGCATGCCTTTGCTCTAAGCTAAGTATTCAACTTCCCTTCTCTTTTAATCTCACGCAAATCTTGTA AAGGCAGATGCTGTTATCCCCATTTTACTGACAAAAAATCTGAGGCTTAATTTGCCCAAATTCACAAGTT AGGATTCAGATCCAATCTGGTTTAGTCCTGATTTTATGTTCTTTTGTTCTTTTCCCTTTTTTTATTTTTA TTTTTTATTTTCGAGATGGAGTTTCACTCTTGTTGCTCAGGCTGGAGTGCAATGGCACAATCTCAGCTCA CTGCAACCTCCACTTCCGTGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAAGC ATCTACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGTGTTTCACCATGTTGGCCGGGCTG GTCTCAAAATCCTGAACGCAGGTAATATGCCTGCCTCAGCCTCCCAAAGTGTTGGGATTATAGAAGTGAG CCACCACGGTCAGCCTTATTTTCATTTTTGAAACAGGGTCTTGCTCTGTCACCCAGGCTGGGATGCGGTG GCATGATCTTGACTCATTGCAACCTTGACCTCTCAGTCTCAAGGAATCCTCCTACTTCAGCCTCCTGAAT AGGTGGGACTACAGCTGTGCACTACCACACCTGGATAATTTAAGGGTTTTTTTGTTTGTTTGTTTGTTTG CTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGTAGAGCCAGGAGGTCTCACTGTTGCCCACGCTGGTCTC GAACTCCTGGGCTCAAGCGATCCGCCTGCCTCCCAAAGTGCTGGGATTACCGACATGAGCTACCGCGCCC GGCCTCTGTAAATAAAGCCTTTCTATACACAAATGAGGTCAAACTAGAGAGAGAGGCCATTTAGGAAAAA TTGCTGTCTTTTCCTCTTTTTTTATCATATACATAGATCTCTTTCTGAATGGTCTCCCAAGGAGTAATTG TTGTCTCCAAGTAACTGAATTTCAGGTGACTTTTACTCTTCATACTCTTGAATTAGTTACCATATGTATC AGTTTTATTATTTATTTTATTTTATGTTATGTTATGTTATTTTGAGACAAGAGTCTCTGTTGCCCAGGCT GGAGTACAGTGGTGTGATCTCACCTCACTGCAACCTCCACCTCCCGGGTTCAAGCGATTCTCCTGCCTTA GCCTCTTGAGTAGCTGGGATTATAGGCATGTGCCACCACGCCCGGCTTATTTTTTGTATTTTTAGTAGAG ACAGGGTTTCACCATGTCGGCCAGGCTGGTCTCAAACTCCCGACCTCAGGCGATCCACCCGCCTTGGCCT CCCAAAGTGCTGGGATTACAGGGGTGAGCCACCATGCCCAGCTATCAGTTTTATTAAAAGAAAAAAGTTA CATTCAGATAGTAAGCAGTTTACATTCTGCATCTAGTTTACCTTGAAGGATATTCTAGGAAGGTGAAGTG CTCTGCTGAGGAGTGGTTTTGTTTCTTAAGCGTTGAGATTTAACCTGATTTTAAATCTTAGGCTGAAGTT CACTGTGACTGTGCTCAGGATCATAAAACTTTGAGACATTTGAAAAACTGACCCAAAATGACTTTTTGAG GAAAACCTTCGTCCTTTTGGCAGCTACTCCCTTAATTTTACCTCCTTCTGGATGTGGAATGAGAGACATC TGAAGTATTGTAAAGAATACTGGCTCTAGGCGAGACCTGCCTGCTTGGAATCCTAGCTCTGTCACAGACA GATCGGGCATTGCGATCTTGGGCAATTTACGGGATGGCTTTGTGTTTTGGTTCTGACATCTGTAAAATGG GAACAATAGTTTCCTACCTTCCTGGGGTCATAGTGAAGACTAAAAGAGCCAATATGTTGGTGTTTTTTGT TGTTGTTGTTTTCTTTTTGGGAAGGAGTCTCGCTCTGTCACCCAGGCTGTAGTGCAGTGTAGTGTAGTGG TGCTGTCTTGGCTGACTGCAACCTCTGCCTCCTGGGTTCAAGCGAATCTTCTGCCTCAGCCTCTTGAGTA GCTGGGACTACAGGAGCGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGCTTTCACC ATATTGGCCGGGCTGGTCTCGAACTCCTGACCTTGTGATCCGCCTGCCTCAGCCTCCCAAAATGCTGGGA TTACAGGCGTGAGCCACCCGCCCAGCCTATGTTGGTGTTTTTAAAGCAGTAACTAGCATAAAGTAGACAG TAATTGCTAGCTTTTAGTTTTATTAATGCTATTCAGTACACAGCATTGATAAGAGGTGATTAGTCCAGAT CCCGGGTTCAGGAAACTATTGAGTCACATGACTCTACGCATAAAAGTGGCCAAAGGTTATCTGCTGTTAC CTCAGACTCAGAACTGTTCCAGCCCTGTCCCAGAGCTCAGCTGAAAGCACAGTATTGATGGAGAGTTTTT CTCCATTCTTACACATCTATAGCAAATAGATGGATACCTATGCTGTGTCCTACTGGGGGCCTCTTTTGTA AGTTTCTGTAGTTTACCGAAGCTTTGGGATTGTGCAATTGGCTAACAGTAAGGAATGTTTGAAAAAACAG CCTTGGGAAAAACTCATAGTATTTACTTTAAGGATATTAAGGTCGATTTCAGTATCTCTAACTGCCCTCA GTGAGAAGCCATGGGTAAACATTCTCTCTAGTCTCAATAATGAGAATAGGCGTGTTTTTCCCAAACAACT TTTAAAAATCTTAAGGATGCCGGCTGGGCGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCG AGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGATAACCCCGTCTCTACT AAAAATACAAAAAATTAGCTGGGCGTGGTGGCAGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCA GGAGAATGGCGTGAACCCGGAAGGCTGAGCTTGCAGTGATCCCAGATAGTGCCACCGCACTCTAGCCTGG GCAACAGCACAAGACTCCGTCTAAAATAAATAAATAAATAAATAAAAATCTTAGGATGCCATAGATAATG CTTAGTATTTCCTTCTTTACTAGAAAGTTTAGCCCACCTTGGTCTGGTTTCTAGCAGTAGTTCTTTTACT TTCTGTCCTAACATTTTTATCAAAAGAACTACATATTGAGTATCCCTAATCCAAAGATCTGAAATCTGAA ACTTTTTTGAGCGCCAGCATGGCACTCAAAGGAAGTGCCTGTTGGAGCATTTTGGATTTTGAGATTTAGG GATGCTGAACCTATATAAATGCAAATATTCCAAAATCCAGAAACCTTGAAATGCCTCTGGTCGCTTATTC AGTTAAGGGATATACAACCTGTATTAATTATTAGCAGTAACATAGTGAAAGTTTTTTTCTTCGTTTTAAC AGTGGCTTTTATTTTCAACTAATTTATTCTTTAGTTTAATAGTGGACTTTTTATTCCTTTTTTTTTGAGA CAAGGTCTCGATACATTACCCAGGACTTTTTTTTTTTGGAGACGGAGTCTTGCTCTGTCATCAGGCTGGA GTACAGTGGCGCGATCTCGGCTCACCACAACCTCTGCCTCCCGAGTTCAAGTGATTTTTCTGCCTCAGCC TTCCAAATAGCTGGGACTACAGGCACGTGCCTCCACGCCCAGCTTATTTTTATATTTTTAGTAGAGACGA GGTTTCACCATGTTGGCCAGGGTGATCTCGATCTCTTGACCCTGTGATCCACCCGCCTCAGCCTCCCAAA GTGCTGGGATTACAGGAACCCAGGACTTTTAAAATCTAGGTTTAACAAAATGGCAAAAGCCCTTGGTAAC ATTTTTCTTTTGAAAAATGCAAGAGCTTTTAGTTTAGTTATAAAGTGAGAAAAAATGTATTTTGGACCCT GAAACTGTAGGATTCACTGAGAACAAGAAAGGGGTATGTGTTTTTGGGAAGTGTTGATCATTTCATGTCA TTATTTCATATATCTTTATTTTCTTTTTTTTTTTCTTTTTTTTTTTTTTGAGACGGAGTCTTGCACCATC ACCCAGGCTGGAGTGCAGTGGCGTGATCTCAGCTCATTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCT CCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCCGCCACCATGCCTGGCTAATTTTTTTTTTAT TTTTAGTAGAGACGAGGGTTTCACTATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCATGATCTGCCC GCCTCAGCCTCTCAAAGTGCTGGGATGAGCCACTGTACCCAGCCGTATCTTTATTTTCATACATAACTAT GAAAAGGAGTTTGAAAAGGAATGCTGGGGAAAAAGAATAGATTATTTTATTAGCAGTATTTCCACTTCAC TGTAACATTTAAATTACTTTAGCTTACATTAATAGATAGGAAAGTCAATAAGTCCCTCTATTCCAGTATT TTTACTATTTCAGATCTCTCTTAAGCATTGTCATTATGTATACATTTTTATAATCCTGTAATTGTAGTGA ATTTAAAATGTTACCATTTTCCATATTAGTTTTACTAATTATTTTCAGTGGTTGTATAACATATCAAGTT AATGTTCTGTAATTGACTTAATTATTTCCCTATTGCTGTATATTTCACTTGTTTCTGTTAATAATTTAGT TCGTAATCTCAAGGGAGGTTTTGATATATGTATTGTCCTATTGTCTGAATGGCTGAACAAATGGTTACCT ACTTAAGATGACCTTAAGTGAGAATGGCCCATAATCCCTAACCAGAATACATAATAATAGCACAGCTAAT GTTTGCTTCATTCTCTAGTCTCCTTTAACAATAGAACATTATTTCAAAGTTTGACAGTGTTTTATAGGAC TATGTTAACCAGATTTCTGAGATGATTAAACATCCTTCCCTCAGCATGTAAGATGCTTGACACAGTTTTT CCGCCGCACATTTTATTTTGTGCTATTTTTTAAGTGGTTAATTTCCTTTTTTTATAGCTTTGTCAGGTTA AATTAATAAGTGATTATGATAGAGAAATATGGCATGTATTCATAATTTAATTTGTCTTTGAGCTAAATGA ATATTTTCTAGAGGAAGACCATCCATCTTAACTCATGCTTGGAACAAGATGGGAAGACAGACAAACCAGT CTTTGTTTAGTTTATGCTGCAAATGTTTAGCTTTAAGCCAGGAGGCTCTGCTGAGAGCTTTTGAGAAACA AGTATTGTAACTTAATGAAACATCCTTACTCACATATACTGCAATATAAAGAAAAAAGAAGAGTGTGATG TTGGGTAACAGTTGGTTTTCTCTGGATGTAGGGATTATGGAGAACTTTAACTTTCTATATGGTGCATTTC TATAATAGTTTTTTTTTTTTTTTACTACAAGCTATTAGTTTTGTAATCAGAAAAAGCAGTAAAAAACAAA AACACTACAGTAGTTTTCCAGATGTCAGTTTGCAGGTCAACAAATATTTTAGGGCCGTCTTGCTGTCTAA TAAGGAAAGAAAAAATCACTGTGCACAGCTTCATGGAGCAAATTTGTTTCCTATTAAAACTCTTCTTGGT GTAGGCAGTACATCATCTTCCACCTGTATAAGGCTATTACATAGAAATTTTGTAGAATCTAATAAGATAA ACTAGAAACATGACATGTTCAGCTGTTTTCTCTACGAATAAACAAATTGGCGCTAAAACTGGTCTTGCTA TCTAGATTTCTAGTTATATCTCAGTTATCTTTTCCCCACATGGGATGTGAAAGTAATGTTATATGCTTTC TTATGTACGTACTTTTGACTTAGGTCAGTCTCCACACTGCATTAAAATTACTAATGAGACAAATTGCAGT TTTCCAGAGGTTCATGTTTCCATTTCTCCTTCCTTGGCTTTCCTGCATTTTTAGCTCCAGTCAAAATTCT ATTTATTATGTATCAACTTTTATAAAATGCTTGGCTTTGAAAAGTATAATTAAAAGACAAAGATCTGAAA TTAATAGTGGGTTTTTAGCTATCTATCATGCATTAAGAAATCAAGTGACCAGGTGTGGTGGCCTGTAATC CTAGCACTTTGGGAGGCTGAAGTGGGAGGACCACTTGAGCTCAGGAGTTCAAGACCAGCCTGGGCAACAT AGCAAGACCCTGTCTCTACTAAAAATAAAAAAAATTAACCAGGTGTGGTGGTGCATGCCTGTAGTTCCAG CTACTTGGGACGCTAAGGTGGGAAGACTGCTTGAGCCCAGGAGGTGGAGACTACAATGAGCTATGTTTGC CCCACTGTACTCCAGCCTGGGTGACAGTGTGTGACCCTGTCTTTCTTTTTTTTTTTTTTAAGAAATCAAG TGTCTTCTTTATTTAATTCTTTTAAAATTTTTATTAGAATCATTTAATAGAAAAAGCATAAAATAAATTA GGTCATAATTCCCTCCTGATGCCCAGATAACAATTTTGAAATTAAATAAGCAAATAAATAAATGTCTCAC TCATCATTAGAAAATTTATATGACAAACCTTCCCAAAGAAAATCACTATTCAGGTTTTCTATAACCTTTC AGAAAAAACGTTTAATGCATATAGCCATAGTTACTTTTATTGCAGTTCCTGGGTACCATAAAACATAACA ATGAAACCATATTCAAAATTTTATAATGAAAGTAAGCAGGTACTTCATCTTTGGAGAGAAGAATGGCATT TCTGTTAAAGTGTACCTCTTTAGAAAGTGGCAGTAGCTCAGAGGATTTCTGTGCCAGGCTCTTAGAAAAG ATACAATGATTAAGACTTTTCTCAAAATCATATTAAAGCTAATCAGAATAGATTGTGAACCGAAATTTGT GTGAATTTTCCAAAACATTGTGCTGAAGTAGTCCACGTCATATATCCCAGTGAATTTGTAACTAATGGCC TCATTTAATGCTAGAAGTGAGAACTGGTAGACCGTACAAGCCTTCCCTTAATTAATTGGTTCGTCTCCTT CTATACTTAGGTTACCAGTACAGAAGAACTAATACTGTAGTTGTTCGTAAACTTGGAGAAAGTCACACTG TATCTGCTCAGAGGCCTGTCCAATCTGCCATGTTTAAGCTTGTACTAGAACTACACCCACCTGAACAGTT GTTACCTTTAAAGTTCTTAGTAGTAATTTTCATATTTAGCTATGAGTTTGTTAGTGTTGTACGTTCATGT GTGAAATTTCTATATGTTTTTCTCTCACTTCATCCCTTCCCTGTTAGATATTAAAGGCCTGGCAAAAAGG ACATGCCTCTCACCCGCATATCCTCAGGTGACCACATGAAAAATTATTCTTGTGTAACTTGCTTTTGGGT TTGGGTGTTTGTTTGTTTGTTTGTTTTTTGAGACAGTCTCACTCTGTTGCCCAGGCTGAAATGCGGTGGC GAGATCTCAGCTCACTACAACCTCCGCCCTCCTGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTAGGAT TACAGCTGCCCACCACCACGCTCAGCTCATTTTTGTATTTTTAGTAGAGACGGTGTTTCACCATGTTGGT CAGGCTGGTCTCGAACTCCTGACTGCAGGTGATCCTCCCCCCCACCTCGGCCTCCCAAAGTGCTGGAATT ACAGGCGTGAGCCACTGCACCTGGCCTGGGTTTGGGATTTATATTGTCAACTGAAACTAAGACTATTGAG GCAGAAATGATTTCATAAAGGTTTATTGGAAGGCCTGGCAAATGAGAATCGACCTGGGAAGACACACCAG CAGACTTGGGGGTTGTTCTGAAGTCTGTCACAAGGTGAAAGATGTTTTTGTTTTGCTGTTTGTTTCTTCG TGGGTTGTTTTCTTTTTTAGAGTCTTACTCTCTTGCCCAGGCTAGAGTGTAGTGTCATGATCTTGGCTCA CTGCAACCTCTGCCTCCCGGGTTCAAGCAGTTCTACCACCTCAGCCTCCCTAGTAGCTGGGACTACAGGC GTGTGCCACCATACCCGGCTAATTTTTGTACTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCCAGGCTG GTCTCTAACTCTTGACCTGAAGTGATCCACCTGCCTCAGCCTCCCAAAGTACTGGGATTACAGGCGTGAA CTACCACACCCAGCCTTTTTTTTTTTTTTTTTTTTTTTTTTTCTGAGACAGGGTCTCGCTCTGTTGCCTG GGCTGGAGTGCAGCCTCAACTTCCTAGGCTCAAGCACTTCATCCACTTCAGCCTCCCGAGTAGCTGGGAC AGCAGGTGAGCACCACCATGCCCAGCTAACTTTTTGTATTTTGTAGAAACAAGATCCCGCCATGTTGCCC AGGCTGATCTCGAACTCATGGCCTCAAGCAGTCCTCCTGCCTTGACCTCCCAAAGTGTTGGGATTACAGG CATGAACCACTCTGCCTGGCCACTTTTTGTTTGCAATAAACATGGGGTCTCATTCTGTCACCCCAGGCTG GAGTACGGTGGCCCCACCATAGTTCATTGCAGCCTCGAACTCCTGGGCTCAAGTGATCATCTCACCTCAG TCTCCTCAGTAGCTGGGACTACAGATGCGCACCACCACACCCTGTATTATATTTAAAAATGTAACTTTTA ATATTTTTTTTTTGTAGCGGGGGGTCACTATGTTGCCCAGGCTGGTCTCGAGTGATCCTCCCATCTCAGC CTCCCAAGTAGCTCGGATTATAGATGTGAGTCACTGGGCCCAGCTATGAAGGTCTGTCTTTATGTTTTTG AGACAGGGTCTGGCTCTCTTACCCAGGCTGGAGTGCAGAGGTACAATCATGGCTCAGTACAGCCCCAACA TTCCAGGCTCAGTTGATCCTCCCACCCTAGTCTCTGGAACTACAGGTATCCACCACCATGCCCAACTAGT TTTTGTTTGTTTGTTTGTTTTGTTTTGTTTTGTAGGGATGGAGTCTCATTATGTTGCCCAGGCTTGTCTC AAACTTCTGGGATTAAGGGATCCTCTCACCTTGGCCTCCCAAAGTGCTGGGATTACAGATTACAGGTGTA AGCCACCTTGCCTGGCCTGTGAAAGGTTTTTAGGAAAGTTTAAAAGAAGGAAGGGTACTCCTCCTCATAC CAGAGTTGTCTTTTCATTGGATGGTACAATATGTAAGTTATAATCGTTGGTTACAAATTATGTTATACAG GCTAAAAATGTCTATGTGCAAGACAATCAGTAGAAGTTCATGCTTCACTAATCTTTTTTTTTTTTTTTTG AAACAGAGTCTCCCTCTGTTGCCCAGGCTGAAATGCAGCAGTGCAGTCTCAGCTCACTGCAGCCTCCACC TCCCGCATTCAAGAGATTTTCTTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGAGCATGCCACCAGGT CGGGTTAAAAAATTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCTGTCTGTCACCCAGGCTGGAGT GCAGTGGCACAATCTCGGCTCACTGCAACGTCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTC CCAAGTAGCTGGGACTATATAGGCGCATGCCGACACGCCTGGCTGATTTCTTGTATTTCAATAGAGATGG GGTTTAACCGTGTTGCCTAGGCTGGTCTCAAACTCCTGAGCTCAGCCAATCCGCCTGCCTTGGCCTCCCA AAGTGCTGGGATTACAGGCGTGAGCCACTGCGCTCATGCAGGCCCCGGTAATTTTTTTTTTTTTTTTTTT TTTCTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTTGGCTCACTGCAACC TCTGCCTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCA CCACGCCCGGCTAAATTTTTGTATTTTTAGTAGATACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGA TCTCCTGACCTCGTGATCCACCTGCCTCTGCCTCCCAAAGTGTTGGGATTACAGGCTTGAGCCACTGCGC CCGGCCAGTCCCCAGTACTTTTTGTATATTTGTAGAGACGAGGTTTCACCATATTTGCCAAGATGGTCTC AAACTCCTAGCCTCAGTTAATCTGCCTGCCTCGGCCTCCCAAAGTGTTGGGATTACAGGTGTGAGCCACT GTGCCCGGCTGATTTCTATTTTCATTGTAGTTGTAGAACATACTTTGTATGATTTTAATACTTTCAGATT TATTGGGGCTTGTTTTATGGCCTACCATCTGGTTTGTCCTGAGAATGTTCTCCTGTGCGCTTGAGATAGA TTTTTATTCTGCTGTTGTTGGGTAGAGTCTTCTATAGATGTTGTTAGATCTATTGGTTAATTACTTTCTC TCTTTTTTTTTTCCTGAAGATTGTGTTCAAATGGATTTAACTACCATGAAATTCATCATAATTCATAATC AGCAATTACAGGAAAGAATAATGTGAGCTTTTGTGGATTTGTATCCAGTTGAGAACATGAAAGATCAGCC ATAGAATGTGATGTGATGATTGGCATAAGAAGTATAGTGATAGAATTATGTAGATCAGGCTAGCTGGCTC ACATCTGTATTCCCAGCACTTTGGGAGGCTGAGGCAGGAATAGCCCTTAAAGCCAGCAGTTTGAGACCAG CCTGGGCAACACAGTGAGACCCCCCCGTCTACAAAAAAAAAACCAAAAATGTTTAAATTAGCCAATCGTG GTGGCACACATCTGCAGTCCCAGCTACTCAGGAGGCTCAGGCAGGAGGATGACTTGAGTTCAGGAGTTTG AGGATGCAGTGAGCCATGATCTCGCTACTGTACTATAAACCTGAGCGACTGAATGAGACCCCTTATCTCA AGAAAAAGAAACAGAATTATTTAAATGCATGAATCTGAATGCCGTGCAGAGAGTATATGCCATATAGAGT TATATGAGAATGTCATGATAGTAGTAGCTTTTTTTTTCTTCTTTTCTTGAGACAGAGTCTTGTTCTGTTG GCCAGGTTGGGAGTGCAGTGGCGTGATTGATCATGGCTCATTGCAGCCTCAATCTCCTGGGCTCCAGCGA TCTTCCCACATCAGCTTCCCGAGTAGCTGGGACTACAGGCATGTGCCACCACACTCGGCTAGAGTGTGTG TGTTTGTGTGTGTGTGTGTGTGTGACTACAGGCATGTGCCACCACACTCGGCTAGTGTGTGTGTGTGTCA ATAGGATTTTTCCATGTTGCCAGGCTAATCTCAAACTCCTGAGCTAAAGTGATCCACCCACCTTGGCCTC CCAAAATGCTGGGATTACAGGTGTCAGCTACTGTGCCCAGCCAAATGTAGCATTTTGAGGAATTCTTTTT TTTTTTTTTTTTTTTTGATATGGAGTCTTACTCTGTCTCCCAGGCTGGGGTGCAGTGGTGCGATCTCAGC TCACTGCAACCTCCGCCTCCCGGGTTCCAGCGATTCTCTTGCCTCAGCCTCCTGACTAGCTGGAATTATA GGCGCCCGCCACTACGTCTGGCTAATTTTTGTATTTTTAGTAGAGACGGTTTAACCATAATGGCCAGGCT GGTCTCAAACTCCTGACCTCAGATGATCCGCCTGCCTCGGCCTCCCAAAGTGCTAGGATTACAAGCATGA GCCTCTGCGCCTGGCCTTGATAAATTCTTAAGAATATCAGTACCTGGCAGGGCACGGTGGCTCACTCCTG TAATCCCAGCACTTTGGGAGGCTGAGGTGGGCGGATCGTGAGGTCAGGAGATTGAGACCATCCTGGCTAA CACGGTGAAACCCTGTCTCTACTAAAAATGCAAAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGT CCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAGCCTGGGAAGCGGAGCTTGCAGTGAGCCGAG ATTGTGCCTGGGCGATAGAGCGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAATACCAGTAC CTTGATGAATTATAGCAACAAATTATTGAGTATCTCCTAAGCAAAGGGTACTGTGTTTAGTGCTAAGGTT GATACTAAGCAGAATTAAAGATGTGAAATTTAATAAATACCCTGTTTTAAGAGCTTTGCTAAAGATGTGT ATGGAATGTTCTGAATGAAACAGACTTAGTAAGACATGAGTGTTGAAAAGTTTTCTCAGTTAATTTAGCA GCACTCAGGACTGCTTTGTCCATGCAGATACGGCTGACTTACTGGGGACTTTTGTTTCTAACATTAGCCA AGCTTACTGTCAACTCTGAAGAGATGTTGGAGTTGTCCTAGAACACTTAAACTTGGAAGTTAAATTGTCT TTCAATGTGTTTGGCAGAGTTATAAAAGTAGACATGAGCCATATTGATAGCGGCACGGCATATGAAGAGC TTCAGAATACTTATGACACTTCTTTGACGTTCTGTGAAAGGCTATAGATAAGTACCTCCAAACATCATGC CTCCAGCCTCACTCTTGCTTAAGGAAATACTCTGAAAGTAGATTTTCTTTCTTTTTTGAGACAGTCTCTC TGTCTCCCAGGCTGGAGTGCAGTGGCATGATCTTGGTTCACTGCAGCCTCCACCTCCTGGGTTCAACCGA TTCTCCTTCTTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCCACCACCACGCCTGGCTAATTTTTGTT CTTTTAGTAGAGACGGGGATTTGGTTGTGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCGCAAGTG ATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACGGGCATGAGTTACTGCGCCCAGCCAAATATCTG TTCTTTTAGCTCTTTGATAGTTCCTTTGTAGTGACAAATTATTTTTTAAAAGCTTATAAATTGGTGTTTC TGTGGAAGATGTTATTTCTCATCGAATGCGTATTGATAGTGTTTTAAGTTTAGACCACAAAGTATTTGTC TTCCATGTGCCTGATATTTACATAGTACTCTAAGCTGCACTGTTGAGTACTGTAGCATCTAGCTTATATG GCTATTTAAATTTATATTAGGCTAAAAATTCACCAGTGCAGCCATATTTCAAGTTTTCAGTGGCTGTGAG TGGCCAATGGCTCTGTTGTATTGGACAGTACAGATATAGGACATATGCAGAAATTATCATTGGACAACCC TGCTGTAGAATGTCACCAGTGTTTCTGGAATCACTGTTTTCGTGCTTGAAGTATTTTGTGCTCCACTTTG AAATGCTAGGAAATCGTGTCTTCCCTTCACATTGTAAACTCTTGGTGATTATTGTGGTCTTTGGAGGTGA AGCCCTTGGGCAGAATTGGGATGGGAGTGGAAAGTAAACTGCTTTGCTGTGGACTAGAAGTAGAATTGGG ATGAGGTGTTCCCGTTCTCATGAGTCCCTTCCCTGTCTGCACTGTTCCCTTTCCTTGTGAACCTTTATTT CCCAAACCCCTTCTTCACCTTTTCCACCTCCAGCCTGTGCAGAGGCAGATAGATACTGGGGACCTGTTGT ACTTTGTTCTGCATCTTCACTAGTGGAAATAAGAGTTCTCTTAGGCTCACTGCTCGGGGGTGGCCTGTAA GATGTTCTTGAGTCTAGTGCTTTCTCTTTTAATTTGGGTGCCTTGTGTCATTGGATGTGTAATGTGGTCT CGAGCTAAATGTGCAGACAGCAGCATCTGAGACATATCCAGAGAGCAGAGGCAGCATTTCTTTGAATTCA GCAAAACCATAATTATTGTGTTTTCTTTTCAGAACTGTGTTTTACGCAAATAATCTTCGGCAAAGTCTTA CTCTTATTGTAGATACTCATTTTAATTCTGTGTGTTAACTTGCACCACAGTTTTGCATAATTTACTATCC TCCTCCAGAAAGCTCTACAGTGTTCCATTGGTCAACGCTTTTGCCAGTAATGTCAGAAATAATGGGTTGG GTGATCTTACTTTCTATATTTAAACAAAATTTTGTCAATTTTCAGTTAGTTGCTTGTTTTCCCTGACCAC TGGGCTATCTCGTATTTCTGGTCTTCAGTCATGTTGTTCCTTTTGTGTGGTGTAACCTTTAGCATTTACG TGCCTTGGCCACCTCTCGTTGCTTAGAACAGACCCAATCTCCAGAAGGTTTTCTGGGTGTTCTTCTTTTC CCTCGGGTTCCCCTTTGCTGCCCCGAGCACCATTGTGTACCTCTTGCCACAGTGTGCTTTTGTTACTCCA TTTCACAGTAGGTTCCTCTATCAGCATCTTGCACAGTTGCCTAGCAACATAGTTTAATGTGTTGGAGGCA AGAAGGGAGGAAATTCACACCATGTTCATCCTACTCAGTGTGAACTGAGTCTATAGTTGATATCCTCTTT GTGTCACTCAATGTTGTCCTGCCTGAGTTCAGGCTTGGTTCTTACGTTGCGGCAGCTCTTTTGCCTTTAT TTAGGCAACAGACCAGAAATAGAAACCCTTGAATTTTTTTTTTTTTATTCCTTTATTTTCCTTGCCAGCA CCTTGGTTAGATTTCTTAACTACTTTTTTCTTGAGTCTTTGTAAAGTATAATTACACTTTACTGTGCTTA CGATCTAAAGAATACTTAATCAGTGTTATTTTTTATTTTTATGTTTTATTTTTGTATTGATTAGGTCTTG CCATGTTGCCCAGACTGGTCTCGGACTCCTGGACTCAAGCAGTCCTCCCACCTTGGCCTCCCAAAGTGCT GGGATTACAGGCATGGGCCACCACACTTGGCCTCACTTTTATTTCTTAAAGTCACTGCCCAATAAACATT CCAAGTTTCCACTAGTTTTTGTTTTTGGACATTTGTTCCATCCAACATCGTGGTGGCATTATATTTTAGT AGATTGTCCAAACATGGGTAAGAAAGATCAACTATGAAAGGAGGTGTCGAACACATTGGCTTTCCCACCT GAATTTGTTCTTTATTCTTTGGATGTATAAAAAACAAGAATAAAACTCACAGGGAGAGTTTGAAGGAACT GTGAAGATTCGTTCTAATTTACATAGTTTACACAACCCATAGCCCTAGGGAAAGTGCCAAAGAACAGCTT TGCAGAGGACTGAAGTCCTCCTGGGAAGAAGAGTCCCTTCGCATCAGATGGCTCTCTTGAGTTTACTTTG CTGCTAAAAAAGTGAGCTGGATTGAGGGGAAGGTTTTCTATTTTTCAAGCTTTGCCAGAACACTTGGCTT AACAAACAGCTGTTTGAAGTCTTAATTGTGTCTCTGTATTTCCAGGGACGCGTTCTGACCTCTTATTAGC AACACAGCTAGGGCTGGCTGGCATGCTTTGTGGTGCCAAACATAGCTGTACCAGCCTGGAAGGTATCCAA ACCGAACAAGATATTGAAGTCAGAAGGAACAAGTGGTACAAATTCTCTCTTAGTCAGAGTTTGGAAAGCC TTCGTATTGAAATTCATGCGGACAGATTTGACACACTTCTGAAAATTTTTTTCATCAACTGACATTTCAG TTCTTCCAGGCCTGGAATAGTGGGTTTCAGTCAACAAGGCACCAATATCTTTTTAAATTTGCCCATAGTA GCCAGCTTTTGGGGTGTATGAATATTAGTGGCAGCCTTGGAGCTTGAACGTTGCATCAATGACCTCTGTT AACAGCTAACCATATGATATCCACAAAATAATGAATTTACATTTCTCATGGGCCCTGGCTTTAGCCATTA CCTCGAGAGTCAGTCTGAGCATCACTTTTAAGCATTCATTCATTGAGTGTCCCTGTCTCTTAGTACTGTG ATGGTCCATGTTTTGAGTAAGTAATGCCATCCTTCAAGCAAAGGAACATATATATGCTTTGAGTTGTTTT TCTGGTAGTGGTAGGTACATTTGCATCAGAGTCAGTAAGTTCTTAAATACCATCAGCCATAGTCAAAAAC AGTTTTTTTTTTTTGAGACGGAGTCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTTGGCTCACTG CAGCCTCTGCCTCTCTGGTTCAAGCAATTATCCTGTCTCGGCCTCCTGAGTAGCTGGGGACTACAGGCAT GCACCCCCACACCCGGCTAATTTTTTTTTTTTTTTTTTTGGTGGAGACGGTTTCACCATGTTGCCCAGAC TGGTCTTGAACCCCTGACCTCAAGTGATCAGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTA AGCTACTGCGCCTGGCCCAGAAACAGTTTTTAACCAGTGCAACTCATACCCATCCATCCAGAGTCCTTGT CTCAGTCTCACATTCTGATCTAACAGCTGAGCTCAGAGCAGCAAAGGAATAAATGGGAGTTTTTCTCAAT ATAAGGTTGACTATGCCTTCTTATATTTTGCCTTCTTAAATTTTCATATCTTTGGCTCATGGACTGTGGT GTAAAGAAACCTTCAATTTTCCTATAACATTGTGCTGCTACTCCTGTTCCAGCTTAAAATCATTTAAATA CGTTACTTTTGATATGTCGCATTGTGAACTCCTAGGTTAGGAATGTCTAGGGGTAAGTTGATGCAAAATG AGGATAATCATTAATTATTAAATTTCTAAGATGTTCTTTTTATATACCAAAGCTGTGTTTTAGAAGGATG ACTTTGAGTAGTGTGGATTGAAGTAGGGGAGAGGCCAGATACAGAGGACCTAGGCTGGAGCCAGCTTATC TGGGTTCAAACTTTGGCTGTGCCATTTGCCATGATCATGATGTTGGGCAAGTTTTGTTCTTTTTTTAAAC TTCTTTGTGTCACAATTTCCTCACTGGAAAAATGGGGATAATAATGGTCCTTGACTCATTAGATATTGTG AGGATTAAACTAACTGAAATATGGAAGCACTTAAAACAGCAAGTATATGAGAAGCAGTTTTGTTTCAGGC AAGCTGATGGAGTATGTTAGTGGAAATGGAAAAGAGTCATATTTATCTGGGTGCAGTGGCTCACACCTAT AATCCCAGCACTTTGGGAGACCGAGGCAGGAGAATCATTTGAGCCGAGTTCAAGACCAGCCTGGGCAACA CAGTGAGACTCCGTTTCTACAAAATAAAAATAAAAAAATGAGCCGGGCATGGTTGCATGTGCCCGTAGTC CCTGCTACTCAGGAGGCTTAGGTGGGAGGATCTGGGAGGATCATTTGAGCCGGGAGGTTGAGACTGCAGT GAGCTATGATCTCACCACTGCACTCCAGCCTGAGTAACAGAGCAAGATCCTATCTTTAAAAAAAAAAACA ACAAAAAAAAAAACAAACGCCTGACGCAGTGGGTCACGCCTATAATCCCAGCACTTTGGAGGCTGAGGCG GATGGATCACGAGGTCAAGAGTTTGAGATCAGCCTGGCCAAGCTGGTGAAACCCCATCTCTGCTTAGAAC ACTCACACAAACAAAAATTAGCTGAGCACGGTGGGGGGCGCCTGTAATCCCACCTACTCAGGAGGCTGAG GCAGGATAATCGCTTGACCATGGGAGGCGGAGTTTGCAGTGAGCCAAGATCGCATCACTGCACTCTAGCC TGGGTGACAGAGTGAGAGACTCTGTCTCAAAAAAAAAAAAAAAACAGCTGAGCACAGTGCCTCTTATCTT TAATCCCAGCACTTTGGGAGGCCAAGGCGAGTGGATCACTTGAGGTCAGGGGTTCGAGACCAGCCTGGCC AACATGGCAAAACTCCGTCTCTACAAAAAGTACAAAAATTAGCCAGGCGTGGTGGCGAGTGCCTGTAATC CCAGCTGCTCCAGAGGCTGAGGCATGAGAATCGTTTGAACCTGGGAGGCTGAGGCATGAGAATCGCTTGA ACTTGGGAGGCAGGGGTTGCAGTGAGCCGACATCGTGCCACTGCACTCCAGCCTCAGTTACAGAGTGAGA CTCCATCTCAAAAAAAAAACCAAAACAACGAAAAAAATCTAAAGAGTATTTTAAGAGAAGAAATAACAGG ATTTAATGATTAGATGAGACATTCTGTTTAGCCAGAGGATTCCAGGGCTTTGAGGCCGAGGAAATATTGG TGTCATTAACAGAAATGAGTAAATTAGGAATTATCTAATTGGAGAAAGGAAGATACTGAATGCTAAAACC ATAGGAAAAAGTTTGACTAAAAGTACTGTGGATAGTTTAGAATCTTTGCCCACTGCTGTATCAAGTAAAG AATAAAGGGCTGAACTCATTTCTCACAAGGTAACTTCTTTATGCATATTTCCCAGCAAGAAGCAGCCTTA ACCTTGAGAAACATGAGTCACTTCTGAGGCTTTACTGCTCTAGGCAGTTTCTACCTCATGATCTCCCTTA AAAAGAGGGTAACGGCCCAGCTCAGTGGCTCATGCCTCTAATCCCACCACTTTGGGAGGCTGAGATGGGA GGATCACTTGAGCCCAGGAGTTCAAGACCAGCCTGAGCAACACAGCAAAACTCTTACCTCTACAAAAAGT TTTTTTAAAAAATTAGCTGGGTGTGGTGGTGCACACCTGTAGTCTCAACTACTCCAGAGGCTGAGGTGGG AGGATCGCTTCAGTCTGGGAGGTCGCGGCTGCAGTGAGCCATAATCACGCTACAGCACTTTAGCCTGGGT GACAGAGTAAGACCCTGTCCTGAATAGGGGGAAAAAAAGAGCAGTGGGTCTGATTATAACCTTTGTGACA ACACTAGATCCCATTACCATAGACTTTCTGAATTGGTTATAGTAAGCCTTAATTTTATTTGTGCCTCGTA AGAATAGTGTGGCCCTATAAATGATAGATTTGAGTGAGAATTCCCACATCTAAATTGTAAGACCCTCATG TACTGAAGCCTCACGTATTTTTCCTTTTTTTTCTTTTTTGAGTTTTTGTTAGTATATATCACAGGAAATT TTACCTGGGAACCTTAAGCTTATTGGTGATCTAGTTATTAGAGATTTAAGAAGTATTTTTCGTTTTCATT GGCTTATTTCAGGGAAAAAAAATTTGTTGGATTACTTTCTTGTTTTTTGAGCCAGGGTCTCACTCTGACA CCCAGGCTGGAGTGCAGTGATGGGATCATGGCTCACTGCAACCTCCACCTCCTGGGCTCAGAGGTGATCC TCCCACGTCAGCCTCCCAAGTAGCTGAAACTACAGGCATGCACTACCACACCCGGCTAATTTTTGTTTGT TTTTTTGTGGAGATGGGGTTTTGCCATGTTGCCCAGGTGCCCAGGCTGGCTTTGAATTCCTGGGCTCAAG TGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGAGATTACAGTGTGAGCCACGGCAGCTGGCCGTTTTTTT TTTTTTTTTGGAAGCTGATCTCAAACTCCTGTGTTCAAGGGTTCAAATGATTGCCTGTGCCAGCCTCCCA AAGTGCTGGGATTACAGGTGTGAACCACTATTCCTGTCCTGGGCATTTTAAAAGTAGAGACCATACTGTA TATAACTTGCCTTTTAGAAAAATAAACATTTTCCCATTGTGTTAAGCCACTGTTATTTGCAGTTAACAGA ATGTGTTATACTAGCCTACACAGTCGAGTTATGTGTGTATTGGCTCACATAATCGAAACGTTGAAAGGTA GTATAGAGATCAGATAAGATTTGATCAGGGCTGAAGCTCAGCATCTCCATGATTTTTTTTTTCCAAGTTC TGCTCTGAAATTTGTAACGGCTGCAAGGTATTTCATTATATGAATGCACTATAAATAAATATTTAACTGT TCTACTACTGGACATTGTAGGGTGTTTCCTTTCTGCCTCCCGCTATTAAAATAATGCTTAGGTAAACATC CTTGTTATGTTTACATGTGTTTTAAAGGAAGAGTAAGACTTGATATGTGATTAGGTACGACTATGAAAGA GAGGAAAGAGGAGAAATAGTGTGAAAAATGGTATTTCTACAGGTAGAAATGGGCAATTTCAATAGAAGGG AGACATGGGCAGCTGATGGGTTGGGTTGGGCATGCTGAGTGTGAGTCCATTCCTCTAGCCATTCTGTTCA TCTTTTTGGTGCTCCTGAGCAACCCCTGGGCACCCACTGGTTATTAATTGTTTCTAACCACTTCTATTTT ATCTTTTAATGACTCATTGTACTGGCGGTTTTTTTTCTTTCACTCATTTTCTTTCTATCCCCCATAGTTC CATTGTACTTTCTTTTTTCTTTGTTGTACTTTAATTTGAACTTTTTCGCTTTGGTATAGATTGTACCAGA TGTTCCTTTTCAAGTTAAACCAAGCAATCCATTACTACCACAGTTGTATAAGGTGAACCTTTTAAGTCAT CTTCTCACCAGAATAACCTGTCCCCATCTAGTCTTCTGTGTTTCACTTTTATTAAAAATGCAAAACTGAT TTATTCTGAGTAAAAGAATAGCTGACTTTTCTGTACCATTATTTATAGCAAAGTAGAATTCATTAAAGTA GGATTTAGAATTTCTTGGATATAAAGTTCTGTCCAGGAAGATTTAAATGGTTCTAATTTAGAGGTTTCGG GGTTTTGTTTTTTGTTTGTTTTGTTTTGAGAAAGTTAACCGTAGGAGATCTAGCGTAAGATGAGCCATTC GTTTCTGCCCCCTTGATGGACTTTTCCCACTGTAAACATAAGCCTCTGGGTGGGCAGCAGATGGAGCTGC AGTGGGGTTGGTGTCGGACACCTGCCAGCTTGTGGAGCTCACATATTCTCATTATAGCAATCATTTGATA CTAGAACTGCCAGAGAATGTCCTAAAAATAAAGGTGGCCAGTACAAGATTCGTTTGATTTTACTCTTCAT GGTCTGCCATTAGAAGTTTGGGTGTTAGGCTCAAAACTACCAAATAAAAACAATTTCGATGTTTTCAGAC TGCTCTGTCTTCTGAAAAATGAGAGATGCTTTTTCCCTGTGAGAATTGACCTAAGTAAATAAGTAGTTAG TAGATTTTTTTCCTAAATGGACCTCAAAACACTGCCTTTTTCTGCTTGGCTGGGTTTTTATGTTTGGATA GAATGGAGAGATTAGATTGGGTACTAGATACTTGTCTGTGAAGCAGTTTAGAGTAATCCTGTTATTCTGA GTTCATTGTCCATAATAGTCTTAAATCTGAAATACCTCCATCCCCTACAGCTGCAGAAAATAGACAACCC TAATAGAAACCTGTCAGATGACTGATTACAGGACGTACTGGTCAGAAATAGTATGGACGATGATCTTTGG GGGTCCATTAAAGATGGTATAAAACAACACAGGGAGGGAAGTTTACATAGTGGTTACAGACATGGACTCT GGAATTGGTCAGACCTGGGTTCCGATCCTGCCTCTTCCACTTGTAAGCTCTGTCTCCTTGGGCAAGGTAT CTGGTTTTTCTGGGTGGACCTTAGATTCTTCATCTGTAAAATGGTTATAGTACCTATACACCTTACAGAG TTGTGAAGATGAAATGGCCTAATTTGTCATGAATTCTGGTACATAATAAATCTTTACTAAATGTAAGCTG CTGTTTGCTAAAGGAGAGACTAACTCATTTCTCAAACATGTTGAGTGTCTACATAGGTATGTAATAAAAC CACAGCCACTACTGTGAAGGATATGGGCTGGCGATTTAAGCCCAGTTGGTTTGAGTTCACTAGTAGAGGC AATGTACAAGGCAGCTTGGTGGCTATGCGTACTATTAATTGGGCAAGGTAATATGGGAGATAGAATATTT TTTGGAACATACTGAGTTCCATTTGGTTATGGTTAAGTTTGTGGTTCTTGTGAGACATAGAGGGAAAGAG ATGTATTGGGCTGTTAGATATGCTGGTTTAGGCTGCAGAGATTTGGGCATATCCAAATAGAATACAGGCA GCAATGAAGTTTGTGCAGAGGTTGGCTCTTTCTAAAGTGAAACTGTAGAGTTAGAACAATATCAAAAAGC AAACCTTGAGGAATGCCAAACTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGT CTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGGGCGATCTCCGCTTGCTGCAATCTCCACCTCCCGGGTT CACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCTGCTACCATGCCCGGCTAAT TTTTTTGTATTTTTAGTAGAGATGGGGTTTCGCCATGTTGGCCAGGATGGTCTCGATCTCTTGACTTGGT GATCCACCCTCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCCGGCCCGCTAGTT TGCTCTTAAGCTCAGCAAAAATTCAGAGTTGTGATTTAATAAGCGTGAGACTTAGTAAAGCATTTTGTAA ATAGAGTATAACATTCCTTGCATTTGTTGTACTTTTGGTTTCCTGAAATAATAGACAGTGTATCTATCAC TCTCCTCACCACAATCCACATAGCTTTCCAGAGTAGAAAAGATACTCCATGGAGAAAGTTTAGAAGCAGA AAATGAAATGAGACTGTGTGGAAGTAAAAGTAGCCTATCCTCTGTAACTGATTTTAGAGGTGACCTGTGA CCTGGCAGTTCCTTATTTATGAGTGGGTACAGGGCACACATTGACCAAAGAAGATAGTTTAGGTGAGGTG CTACCCTATCTTTGAGAATGGGACTCTTGGCTCTTAAAATTAGAAACCAGGAGATCTATGGGATGGAAAA TAGCCTTCCCTTTCCCCCAAATCAAACAGATACACATACTTTGTGACAGGAATAGATTATGAAATATGGT GTCCAGAACAAACTGTCTGCTGGGCTTTTAAAAGGGTTTTATACTTTCTGCTGGGCACCTAGAGCACTTA CTCTCCCTTCTGTCTCCTTTTATTACCCACCTCAAGCAGTCATAATTTTTTTCCTTTCCATTCCCTAGGC TTAGCCCTCTTCCTTCCTCTACCCCCAAAATGGGAAAGCCTTTAGTATTTAACTGTAGTACTTTATTTGG CTGTCAGTATTTGTCATATTAGTAATTGGGTGAGCTTGGCTGGAGGTGGGGGGCTGTTCTGCCCTTTTTA AGATTGGCCCACACACCATTGTACTTAGGTACCCACACAGGAGCAGAGCAAGTTGGCTAGATTTTGAATA CAAAAGCATGATATTGTGGGTGGGAGCATGTATAGTTTTAGAATTTTTAAAGTAAGGCAAAAACCATGTA CCTAATGAGGCCAGTGGAATAAACTTTACAACAGATAGAACTTCTGTTTCTGTTTAACACCCAGCAATAA AAATGCTAAGAACAGGGATAAAGTGAAAATTATTAAGCCCTTGTATCTATTGCTGACTGGTAAAACCAAC ACATCAAAAAATATCTTTTGGCTCCCAACTTGTTAATAGTTTCTGACTTACGTGTGTTCTGAGTGATTTG GTGGAGTGAATGAGCTAGGTCTTGATTTTTCCCTCAAAGGATTGAAATTTGGTTCTTGGAGGGTGAAAAA ACAAAACTCAACTCTTCATGCATAAAGCACAGATAAACAGTACAGTACATAAATATATGTGTATTTTCAT CTGTGGTATCAGAATTTCATGAGAAGTGGTAATTAAGGAAAAAATGTCTACAAAGACATGGCGGAGGTGA TGATGATTAATAAAAAGACTGAGATATGGGGCTCTCCCCTTTGAGGACCTGTAGGACCTACGTATCTGTG TCCTGGAGAGGCTAGTGGCCCTTCTTTATTTTTCTCATCTCTAAAACTGGGCCTGAGGGTGATGAATGGT GTCACTAGCTGAAGTGCTTCAGGAATGCCAGTGGGTACTCTTAGGATTATTATGGCACAATGTATGTGGT TCTGACACTTAACCAGGAATACAAGCAGTGCTTTACATACTTTCCTTGTATTGGAGAGCCTAGTGGTTGC ATTAAACATGAGGGAAAAAATCTGAAAAAATACCAAGTATGACAAGAAATGAATATTATTTTAATAATCC CTTTTTTTTTTTTAATAAAGACACAGACTGGTCTCGAACTCCTGGCCTCAAGCAATCCTCTCATCTCTCA TTTTAATAGAGTTGCTCAGTTAGTAATGGACATGTAATGAGCGTAATATATTTTGCTCATGAAATCCTAA TGTTTTCAGGGATATTAAAACTTAGTAAATTGGGAAGCTTTTTCCCCCTAGTTTGGTGGGGAGTTTAATG CCCTGCATGCATCACCGTCTCCCCACTCCATAATTTTTAAGGATGGCTCCTCAGACTCTGTGTATGAGTA TTTCCCTCATACCATATTTGGTATTTTTGCAAGTAGATAACTTGGTACCTTTGTAATATGATAAGTCTAG ATAGATGAAGGAAGTAGTGTTTCCTGATAAATTACGCAGTTAGTTGGTAAGGAGACGATAGGATTTATGA TGACATTTTTAGGAGTCAAGTGTTTAGACCCATTTTTCTGAGGATTTCCCTGTCTTTCCCACAGCATAGG AGACCATCTTGTCCTATTTTTCTGTCCTTATACTGCCTGAAGGAAAGATGTGCATTTGGATCTTTGCCAC TCTGTAGTTTAGTTTGTTCCCTTGTCCTCGTTTAAGACAGGTTCGCAAAATGTTTTTGAGAACAACACAG ACTGGAATTTGAATTGAATTGCACTTTTTCTTTTTATTAGCTGTTTGTGGTCAAGACATCTGACCTCTTT GAGCTCTGGTTTGTTCATCTGTAAAATAAAAGTACTATCTCTGGGAAGGGTTGCCTTTAATACAGGAAGG AAGTGTAACAGGTACACAATATATTGTACCTTTTAAAAGTTTGACTTTAGGTCAGGCATAGTGGCTGATG CCTGAAATCCCAGCACTTGGGAGGCTAAGGTGGGAGGATCGCTTGAGGCCAGGAGTTTGAGACCAGCCCT GTTCAATAGAGCAAGACCCCATCTCTACCAAAAAAAAAATTAAAATTAGCTGGGCGTGGCAGCACATGCC TGTAGTCCTGACTGCTCCAGAAGCTGAGGTGGGAGTTCAAGGCTGTAGTGAGCTGTGTTCACGCCACTGC ACTCCAGCCTGGGTGAAAGAGCAAGAACCCTGTCTCAGAAAAAATTGAAAAAAGTTTAAAGTGAAAAAGA ACATAGCATCATAGGACTCTTATTTTATAAGGGGATTTATCTGAGGCCCAGAGAAGCCAAGTGGGCAGAG AGCAAGGTGAGCAGGAGCAGCTGGGCCCATGCCACAAGGTCCCTGTGTGTCCTTTTTGCCCCACAAACCT TGCTTTTGTATTAGGTCACTCCTTACTGTACAGACACAAGTGGTAATGATGGTGTTTTGCTGTCCTGTGT GAACTAGTGTTGAGTTTGACCTCAGTTGAATCAGTAGGGGATTACATTTCTGTGAATTCTGTGGAAGCCT TCTAAAATCAGATAATTACCTTGCTTGTATTTGTGACTTCAGTTACTAGGCTTTATGATAGGAATATGGA TTGGAAAATACTCTAAAATCCCATCTGGTCCTTTGATTTTTGTGTGTGAAGGGCTTAAAATTACCAGGAA TTGTTCCAGACACAGAAAACTAGTTCCTGTTGTCCAGAATTATGTTTCTAAGATAGTAATGGGAGGACTA AACTTGTAATCTGTTGAAAACATATTTTTGAGATTTAAGTTATTGATGCATTTGTTTATTGTGAATAAAA ATAAAACAGAGTAAAAAATCATAATCACATTTCCTTGTTTACATTTGGGAGATCGTTTATGATTTCTTTT TAATTTGACTGTTTAAGTATATTAGAGACAAGGTCTCGCCATGTTGCCCAGGCTGGTCTCTAACCCCTGG CCTCAAGCAATCCTCCCACCTCAGCCTTCTAAATTTCTGAGATTACAGGCATGAGCCACCATGCCCAGTC TGTCTTTTTTTTTTTTTTTTTAAGACAGAAAGAACTTTGTAACACACCACTTTTTCCAACAACATTTATC TTTCCAAGACAAGTCAAACACTTATTGAATGCCCTTGAGTATATACCAAGATTAATAGCCGAGGCTACTA CCCACAAGTAGTTCAATTTAGTAGAGAAAAGAGTATATTGAGACAGGTATACATGGTTCAGTGGTGGGAA GAAAGTGATTCTTAAATTAGGTCTTGAGTTTGCCATTTTAGGCAGAGAGAACAACATATACAAGTGTGAA AATCATAAAACATTCTGGCAGTTGGGAAACCGCAGGTAGCTTTAGTGTTGTTGAAACTTGGAGTTCAAGG CAGGAAGGCAGGAGATGACAGGGACTGGCAGGTGGAGATTGGGGAGTTAGGCAAGGTCTGGGCCATGGAG AGCTTTGTGTTCAGTGCTGTGCTTACTCACACCAATCTGAAATTATTATTATTATTTATTATTATTATTA TTTTGAGACAATGCCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCATAGCTCGCTGCAACCT CGAACTCCTGGACTCAGGTGATCCTCCTGCCTCAGCCTCCCAAGTAGCTAGGATTATGGGCATGTGTCAC CGTGCCTGGCTGATTTTTGTATTTTTTGTAGACATGGGTCTCACTTTTGTTGCCTAGGCTGGTCTTGAGC CCTTGGCTTCAAGCAGTCCTCCTGCCTTGGCCTCCCAATGTGCTAGATCACATGTATGAGCCATCAGCTA TTTGGAGACAATTTAACCAAAGTTGTATTGTCTATTATTCCTCTTTTTTTTTTTTTTTTTTTTTTTTGAG ATGTAGTCTCAAACCCTCCTGGGTTTAAGGGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAG GCGTGTGCCACCACACCGAGCTAATTTTTGCGTTTTTTAAATAGAGACAGAATTTCACTATGTTGGTGAA GCTGGTCTTGAATTCCTGACCTCAGGTAATACACCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGTG TGGGCCACTGGCCTATTTTATATATATATATATTTATATATATATATATAATTTTTTTTTTTTTTTTGAG ACAGAGTCTTGCCCTGTCGCCATGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCTGCCTCC TGGGTTCAGGTGATTCTCATGCCTCAGCCTCCTGAGTAGCTGGGATTTACAGGTATGTGCCACCATACCC AGCTAATTTTTTGTTTTTTTTTTTTTTTTTTTTTTTTTTAGTAGAGATGGGATTTCGCCATGTTGGCCAG GATGGTCTTGATCTCCTGACCTCGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATG CCCAACCGCGGCTGGCCCTGTCTGTTACTCTTAATGATCTTAATGACAGCTCTGTCAGTGTTAACATGTT TCTCCGTTTTAGGATAATGCCATGAATATACAGAGCTAACCACTCAGCAAACACTCAAAGGTAATGGGGA ATGAGCATGCCACAGATAAATAATGGAAAGAGGCTAGAATGCAACTTAAATTGGAATTTAAAACAGACAA AAACACACTCCACCCATAGTGTAGGAGATATTTAGTAACATGAATTGGAGTTTTAAAACTCTAGTCAAAA TGTTAAATATTTGAATTCTTTTCTAACAATTTAGGTAAAATGCAATTTGGAATAATTTTAACAGGGCTTG TGGCCACATTTTTGGTTTAAATATTTATTTACTTAGCTATTTTCTTCCTCTATACTTGTGTGGGCAGTGA ACCTAATAATTAGGTTAAAGGATTAAAAAAATCAATTCCAGAGAGCTCACCTTTGACTAACATAGCAAAG ACCATCATTTAGATTACATCAATGGTAATTTCAGGCTAGACATGGTGGTTGGTGGCTCATGCATGTCGTC TGCAACCTCCACCTCCCGGGTTCAAGCGATTGTCTTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCA CGCGCCACCACGCCCAGCTAATTTTTGTTTTTTGTTTTTTGTTTTTTTTGAGACAAAGTCTCACTGTGTC GCCTAGGCAGGAGTGCAGTGGCGCGATCTTGGCTCTCTACAACCTCTGCTGCCCAGATTCAAGCGGTTCT CCTGCCTCAGCCTCCCCAGTAGCTGGGATTACAGGCGCCTGCCACCACGCCCAGCTAATTTTTGTATTTT TAGTAGAGACAAAGTTTCACCATGTTGGCCACGCTGGTCTCGAACTTGTGACGTCAGGTGATTTACTCTC CTCGGCCTCCCAAAGTGCTAGGATTACAGACGTGCACCACTGCTCCTGGCCTGCCTCAGTTTTAAGCATG AATAGACCGTCAGGGAGCACCAGATGTTTGAGGAATGGAATATTTGGGCCATTGAAGGATTTTAAGCCAA ATGACCTGACAGTCCAACTTTAAAAGAAGACAACTTTATTTTTTCAAAGAACAATTTTAGATTGATAGAG AAGTTGTACAAAGAGTTATCATATGCCCCACATTCACTTTCACCTATTACTAACATTATTATGGCGTATT TACTATTAATGAGCCAATATTGATACGTTATTATTAACTAAAGTTCATACTTGATTCAGTATTTCCTTAG TTTTTCCCAGTGTCCTTCTCTGTTCTACGGTCCCATCCAGGACACCACATTATACCTAGTCATCATATCT CTCTAGACTCCTCTTGGCTGTGACATTTCTGACTTAACTACATCAGTGTAGAGTGAGAAATAAAAATTAA AAAGAAAAACCCTCAAACATTTCTGCCTTACATTTTAATGATGCTAATTCTGGTTGCAGGATTCAGAAGA TTCTGATGGTGGCAAAGTGAAAGCAGTGAGACGGATTAGGAAGCCACTGCAGTAATCCAAGGCAGAGATA ATGATAGGGCTGGATCAGAATGATGGTGGTAAAAGTGAAAAGTGTTCCATTTGGGGATGTTATAAAAGCC ATTAGCCTGGATGGGGAAACTAAAGGAATGAGTGTAGATGGAGAAGAAAAGAGTTCCAGGGATGGAGCCC TTGGGGCACCTGAATGTTTAAAAGTTAGTGAGATAAGAAACTAGCAAAGGAGACCCAACAGGAAGTGGCC AGTTACGTAGGAAGAAAAGCTGGGAAATGATGTGTCTTGGAAGCCAAGAAAGTGCTTCAAGGTGAAGGAA ATGATCACTTCTGTTTTGCCCTGCTTATAGGCCAAGTCAGATGAGGGCAGGGAATTGACCTTTGGATTCA GCAACAGGAGCTGATTGGTGACCTTGAGTAGTTTCAGTAGAGTGGTACGAGCGGAATCGTGCTTGGAAGC TGGTTCAGAGAGGATGGGTATGCACAGGGAAAGCTGCACAAGGAAACTTGCTGTGGTGATAGATGTGTTC TTTATCTCAAAGGTAGCAGATATGTAAATTATACATGCAAACTAATATTTATGAAAGAACGAATGATAGG GTCTTGCCCTGTCACTTAGGCTGCGGTACAGTGGTGTGATCATGGCTCATTGCAGCCTCGACCTCCTGGG CTCAAGCGATCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGTACACACCACCACACCTAACTA ATTTTTAGAGAACAGGGTTTCACAACATGTTGCCTAGGCTGGTCTTGGCTCCTGGGCTCCAGCGAACCTC TTGCCTCAGCTTCCCAAAGTGTTGGAATTACAGGCATGAACCACTGTACCTGGCCCAAATATTTAAATAT AGGTAATAATATGTATATTGAAGTATTTAGGGGGAAATGTACTCATATCTGTAACTTTGAAATGCATTAA AAATTAAGATAGATAGGGCCAGGTGCGGTGGCTCATGCCTGTAATCTTAGCACTTTGGGAGGCCAAGGCG GGTGGATTACCTGAGCTCAGGAGTTCGACACCAGCCTGGGCAACATGGTGACACCCTGATTCTACTAAAG TACAAAAAAAAATTAGCCGGGCATGGCAGCGTGCGTCTGTAGTCCCAGCTACTCGAGAGGCTGAGACAGG AGAATTGCTTGAACTCGGGAGGCGAAGGTTGCAGTAAGCCGAGATCACGCCACTGTACTCCACACTCCAA CCTAGGCGACAGAGCAAGACTCTGTCTCTTTAAAAAAAAAAAAAAAAAAAAAAGAAGAAAGGAAAATTAA GATACATCAATAGGAGAGAGGGATGTATATAGATGGATAGATATGTGACAGAGCAAATAACTTAGGTCAA ACTTGTCCAGCCCCACAGCCCGCAGGCCACATGTGGCCCAGGATGGCTTTGAAGGCGGCCCAACACAAAT TTGTGCTTTCTTAAAACATTATGAGATTTTTTTGCTTTTTTTTTTTTTTTTAAGCTCATCAGCTATCATT AGTGTTAGTGTATTTTATGTGTGGCTTAAGACCTTTTTTTTTTTCCAGTATGGCCCAGGGAAGCCAAAAG ATTGGACATCCCCGATTTATGTGATGGATAAATGTATTCACTGTAAAATTCTTTTCACTTTGCTTTATGC TTGAAAGCTTTTATAACAAGATGTTTGGGGAGGAGGAGAGAACTGGGACAGAGAGTATAGACAACTGTTC CAGAAAGTTTTGATTTAAAGGGGAACAGAGAGATGAGGCAGTAGAGTCAAAAGAAGTCTGCTTTCACCCC ACTCCCAGAGATGAGAGAAATGACAGCATTTTTATTTGTTGATTAGAAAAATCCAGTAGAGATTTTAATT AAAATTGATGATGCAGAAGAAAGGAAAATAACTGAGTTAATGTCCTTGAGCAGGCAAGAAGAGATGGGAT TCAGCACCTTCGTAGAATTTTGTTTTGCTAGGAACAGGGACAAAAGTACGAGTACAGGTCCTGGCCAGGC GCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCAGGAGT TCGAGACCAACCTGGCCTACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGTT GGCATGTGCCTGTAATCCCAACTACTTGGGAGACTCCCGAAGTGCTGAGATTACAAGCATGAACTGTGCC CGGCCATAGATCTGTTTTTATTCACTATGGCTGGGTTCTCAGTGCGCCCTTCCTATCTGAAAATTCATAT TCATCAGCTATGAGAAGTTAAGTTTTTCCTTTTTAAAAAACATTTCGTAGTGTCTTTTCTTCTATTTTCA CTGTTCTCTTTCTGGAAGTTTGAATAATAGCTGTCACATCTTTTGGAAGACTGCAGTGGGCTCTTCCAGC AATTCTTGAATCCAGCAGTCCCCAACCTTTTTGCTACCAGGGACTGGTTTCATGGAAGACAATTTTTCCA TGGAAGTGGGGGGTCGAGATGGTTCAGGATGACTGTTCAACCTCAGATCATCAGGCATTAGATTCTTACA AGGAGCGGGCAACCTAGATCCCTCGCGTGAGCAGTTTACAGTAGGGTTTGTGTTCCTACGAGAAGCACTG GCAATGTGGTGAAACCCCATCTCTACTAAAAATAGAAAAATTAGCCGGTTGTGGTGGCAGGCACCTGTAA TCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACATGGGAAGTGGAGGTTGTTGCAGTGAGC AGAGATCGCACCATTGCACTGCAGCCTGGGAGACAAGAGTGAAACTCCATCTCCCCCCCCCCCCCAAAAA AAAAGACCATGAATAAACTTTGCTTGTACAACTCTGAATACCAGAAAACAATGTCTCTTCCAAGTTCTGA GGGAAAATGCTGTTCAGCCCAGGATTCTGTTGAAATCTATACCCAGCCGAAATAGCCTTCAAGTATAAAC ATAGAATCAAGACATTTCCAGACATGCAAGGACTCAAAACATTTGCCCCTCACGCACCCTTTCGTTTTTG TTTTTTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTACAGTGGTGTGATCTCGGCTCACTG CAACCTCCGCCTCCCGGGTCCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATG CACCACCATGCTTGGCTAATTTTTTGTATTTTTAGTAGAGACGGAGTTTCTCCATGTTGGCCAGGCTGGT CTTGAACTCCTGACCTCAGATGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCC ACTGTACCTGGCCAGAATTTTTTTTGTTGTTGCCCAGGCTGGAGTGCAGTGGCGCAGTCTCGGCTCACTG CAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATG TGCCACCACACCTGGCGAATTTTTGTGTTTTTAGTAGAGGCGGGGTTTCACCGTGTTGTCAGGCTGGTCT TGAACCCCTGACCTCATGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGAATTACAGGTGTGAGCCACCG CGCCCGGTAAAAATGGTTTTTTTTTTAAGGGCATAGAAACTCGAGGAAATACAGAAGCCCAACCAGTAAA GGAAGTACAGTTGACCCTTGAGCAACAGAGGTTTGAGCTGCATGGTTCCGCTTATACACGGATTTTTTTC AGTCTACATGTGTGTCAAAAAGACAGTATTCACAGGATGCACAGCCCACTTACGCAGAGGGCCAACTGTG GGACTTGAGTATGCACAGATTTGGGTATATGCAGGGGTCCTGGAACCAGTCCCCCATGAATACAAGGTAC AACTGTGTCTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGAAGTGCAGTGGCGC GATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCT GGGACTACAGGTGCCCGCCAGCACGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACTAT GTTAGCCAGGATGGTCTCGATCTCCTGACCTTCTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATT ACAGGCGTGAGCCACTGTGCCTGGCCAACTATGTCTTTTAAAAAAAAAAAAAAAACAAGTTAACTTTTTC TCCCAGAGAACGGTCTTGTGAGCTTGATGATGAAAATTCAACTAGAGAAAACTGGAAATTTTGGTGCTAG TCAGTTCAGAGTTGATAGCCTTAATCATTATTGATTTATTATACATAGACATCCGTGACATTAAAACACT TTTACTGCATAGAGGGGATCATAAAGGCTGAGTGATACCAGGCTGTAGCTGCAAACAGTAGGGATATCTT AGTTGTCACATAATATGTCTGATCGCTTTTCTCCTTTGGGAAACTACTTGTCATTGTGAGCAGGAGAATG AACCGTTTATGCCTGGTCACCCTTCCATTTCCAGGGAGCGTGGATGTTCTGTTGGTACTGGGGCCTGACC CAGAATCATGGGATTGTACACACATTTCTCCTTTAAGCACAACATGAAATCAGGAAGTTGTTCTTGTAAC TTGGAGTTGCGGGTCTGACAAGCCTGTTGTTTGCGTTAATACATCCTATCATTTAGCCGTCTTAGTCCCT CTCTTCTCTGCAGGTTGTGACAGTTCTGTGGGACAAAAGTGCTGATTTTTCACATGGAGCAGCGTGTAGG TGCTTAGAGAAAGAACTAGAGGCGGAGCAAGGCTGAGCTTGTCTCTTCATGATGGTGCCTGCCAAGAGCA GGGGCTGTGCTGCGGCTGCCCTGCCCCCCAGCCCTCCCAGTGAACCTGAACCTGCTCCTCCTGAGCTGTG TAGCTGCCTGAAGGAGGCCAGGACCTGGGTAATTAATTACTAGAGAAGCCTCTGGTCTAGCAGCAAAAGG AGGTAGTTAATTTAGCCTGCCTGTTAACAATAGTTATATTTGTCTCCGATTCCATTAGAGATGCTTAGGA AAAGGTTTTTATATCCTGAACCCTGATGTCCATTTTCTTAATGCAAAGGCCTGTACTTGGGGTCTTGTAA GCCCCCTAATGTCACTCTTTGAAGTGAAGTAACTATACGTGATAAGTGAATAAAATGTGTCAGAGTGTAC TACTTAGAATTTTCATAGATTGTAAAGATTTTCTATATATTTATTTGAATTGGTAATTGGTTATGAGCAG TTTGGTGTAGCTGTTTTTAATTGTACAACAATTAAGATATCACCTATATTCTCGAAGAATGGGATCATTC CTTCTAGGTGAGGGATTATCCCTTTAATATATTTTCTTTCTCTTTGTCTTTGTTTATGGTGGAGAATAAT TAAACTTTTTTTTTTTTGGAGGTAGGTCTTGCTCTGTCACCCAGATTGGGGTGCAGTGGCATGATCATAA CTTACTGCAGCCTCAGCCTTCCAGGCTCAACTGATCCTCCCACTGTAGTCTCAGAGTAGCTGGGACTACA GCCGCACACCACTATACCCAGCTAACTTTTTTGTTCTATTTTTTGTAGAGACAGGTCTTGGCTATATCCC TCAGCCTAGTCTTGATCTCCTGGGTTCAAGTGATTCTTCCGCCTCAGCCTCTCAAAGTGCTAGATTACAG GTGTCAGCCACCAGCACTTGGCCGTCTTCCTCTAATTTTTAATTTTTTCACTTTGAGAAGCCTATGATAT GACATGGAATTTGATGTCTCATCCTGTGTGGTCCTGTGCACCCTGTTCCTACAGAAGTACAGAGGGAATC TTTTGAGAGGGAGGGATAAACTTAGATTCTTAAAAATAATGCATGTGGGTTTTTCAGTGTTCATTTTAGA TTCTCTTCAAAACAGTCAGAAGCCCCCTACCCTAATCTCAATTCCTGTCTGCTCCCTCCTGGCTCCCTGC AGTAACCCCTTCTCCACCTGATCTTCCTGCTGCTGCTCTTTGTCCCCTCAGAGCCGTGTGCCACACACAA GCCAGAACCATCATCCTAATGAGCAAATTCCCCAAGTCCTTATTCTGCCCTGCACAGTCGGGCTCAGTTC TCTGTCCCTGGTCTCCCCTAGACTATGCCACATCCCTTCCTGCCTGAGAACTTTTGCACCTGCGCATTCC TCTGCCTGGAATGTTTCTTGCTCTCATTTGTGTCCTCAATGCCCGTCCCCAAGCCTCACTACAGCCTACT TACACTGAGGGTTTCCATTCAAATATTACCACCCAAGTGGCCAGGCACGGTGCTTCACGCCTGTAATCCC AGCACTTTGGGAGGCCAAGGTGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTG AAACCCTGTCTCTACTGAAAATACAAAAAAATTAGCTGCGCGTGGTGACGGGTGCCTGTAGTTCCAGCTA TTTGGGAGGTTGAGGCAGGAGAATGGTGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCGCC ACTGCACTCCAGCCTGTGCAACAGAGCGAGACTCCGTCTCAAAAAAAATAAAAATAAATAAATAAATGTT ACCGCCCAAGTGAGCTTTCCTTGCATTGATTAGATTCGGTCTCCCCAAGATGTGCTTTCATACAGAGCAC TCTGGACTCATAGAACTTACACCTGAAGTTGTAGTGAACTTGGCTTCCCCTGCTGTCAGCTCTTTGAAAG TAAGGCTCATTTTTAAAATTGTATCCCCAGGACCTAGCATAGCTCCTAACTCAAAATAGGCACTCACTCA TACTTGTTTACTCAGTCTTTTTTTTTTTTTTTTTCCCCTCAGAGATGAGATCTTGCTATATTGCCTGGGC CAGAGTGCAGTGGCTATTCACAGGTGCAATCATAGCACACTATAGCCTTAAACTGCTGGGCTTAAGGGAT CTTTCCCAGGTAGCTGGGACTGCAGGCATATGCCACTGTGCCCAGCTGCTCCCTTAGTCTTGACTATGTA TTTTTTTTTTTTTGGTTGTTTTATTAGGATAGAGTCCTAAGAATGGCATTACTGGGTTAATAGGTATGAA CATTAGATCTTTAATACATACAGTCGAATTACTTTTCATAAAGCCATATACCTTTTTATATTCCCACCGA TACTATCCCTATCACTAAGTATTAACTTATTTTCATCTTTGCCAATATGATCATCCAAAGTGAGGCAGTG GGTGGCCATCAGATGTCTGAGTCAGCAGGGTGTGGTGGCTCACGCCTGTAATCCCAGGATTACAAATTTT GGGAGGCTGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCTTGGCCAAAATGGTCAAACCT CGTCTCAACTTAAAATACAAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGCAATCCTAGCTACTTGGGAG GCTGATGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGGTGCGGGGGTTGCAGTGGGCCAAGATCGCAT CACTGCAGTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAGTCTGAGTT ATGAAAACAGAAGGCTCGAACCAGCCCCTTGATCTAGTTATTCTGGGCAAGCCTACATGTGTCCTCGAAG GTTTCTGGGCTCTCAGGTTTTACAGCCTTAGCAGGCTAAAGGCAACAGGGAGGACAGCTTGTCTTATCTG TTAGGCAGTAGTTTTAGTAACATGGCCAGCATGGTTACCTGTAAGAGAGGACCCTGCTTGATTGAGCCAC ATCCAGCTGTCCAAATGTATGTAATTACCATTTATCATTGAAACATATGACAGCTCCATCAAAAGAGAGC AATGTGTAGTCTGGCAGAGGACAGTAGGATTAAACAAGAATGGCTTCTTTTATTTAAACTCAATGAAAAT ACAAGAGGGAAAATTACTTTGCTTACTATACCCTCTCACCTGTTATAAGCTGTTCTACCTTTAGGTTCTT GCCCTATTCCTAGACTATTTGAAGTTGTCCTTTTTTCTAGAACGTCCACACATGAGTTGAATTTTCCATG TCAGCCATGCAGCTAATTTAGAAACATGTTGCTGGGTTGGGCGCAGTGGCTCATGCCTGAAATCCCAGCA TTTTGGGAGGCTGAGGTGGGCGGATTGCTTGAACTCAGGAGTTCGAAACCAGCCTGGACAACATGGGAAA ACCGCATCTCTACAAAAAATACAAAAATTATCCAGGCGTGGCGGCGTGCACCTGTAGTCCCAGCTACTCA GGAGACTGAGGTGGGAAGTTCACTTGGCCTAGGAGGCAGAGGCTGCAGTGAGCAGAGATTGTGCCACTGC ATTGTCTAGCCTGGGTAACAGAGTAAGACCCTGTCTCTAAAACTGAAAAGTAAATAGAAACATGTAGCGG TGAATTCTGTGTCCAGCTCAAAATCAGCAATTTCCCTTATCTCACTTTTTTACTTATTTCCTCTTTATTT ACACACATAGCTCCCTTAGCTCATAAACACTTCTGAGGGCAGGGACCATGCCTTTTATTCTTATTCCCTT TTCAGCTTCCTAACACAATGCTTTCAGTGTAGTAGACACTTGAACAATATCTAAAGTGCAATTCAAAGGG GCAGCTACTGCAAGTCATTATGCCAGTCTAGTAATGGTCAGATTACAAATCTGAGGTTTTTATACCTTCA CCCCCTTTCTCAACTTTTAATAGTAAACAGAATAGGGCTGGGCATTATGGCTCATGCCTATAGCCCAGCA CTTTGGGAGGCTGAGATGGGAGGATACCTTGAGACCAGGAGTTCCAGACCAGCCTTGGCAACATGGTGAG ACCCTGCCTCCACAAAAAAATTTTAAAAGTAGCCAGCTGTAGTGGCTGGCATCTGTAGTCCGAGCTATTT GTGGGAAGATCTGAGACGGGAGGATCACTTGAGCCCGGGAGGCTGAGGCTGCATTGAGCTGTGATTGTGC CTCTGCACTCCAGCCTGGGCCACAGAGCAAGACCCCTGTCTCAAATTTTGAAAAAGCGGTTAACAGAACA GAATTGTTTGGCTCTTTTATAGTTTTCTTCTTCCAAGTAGTTGGTAGAATTTGGATACTTTCTGCCCCAT AACAAATGTCACTTTATATAAAGGAGCATGTCCTTAATGCATTCCAAAAGACATATACAACTGATTTTAG GCTAATTTCAGTCTGAGTCCTGGTAGAGAACACCTGACACACTTAAATTGAGAGGATTTTAATAATGAGA CTATTTGCAAGGTGTTGACTCCAGCTGGGGACCTCCACACTCAGCCCACTCAGGCTAAGTCTTGGTTGCG CACCAGCTCAGCTCATGGCTGGGCTGGGTATGCCCCAGCTCACCTGTGTTATGGCTTGTTCCCAGGTTCA GCAGTTCCCAAGGTCTTGTCCTGTGTCTGAGAAGAATGAGGTTACACTGGCAATTTAAGGGTGAGGAGGG TGGAGAAGAATTTTATTGAGCGGTGAACAGCTTTCAGGAGCGGAGGAGGTAGTGGTTCCCCACCCCTGAA GTCTGGTGGTTTCTCTCCCAGTGTGGCTGGGTGGGGGCTTTTATGGGCTCAGAACAGGGGCATGCATGCT GAATGGTTTGTGGGCATGCAAAGAAAGGCTAAAGCAAAGGCACCACTCAAAGATGGGCATGGCAGTGTAG AAAATCAATTCGGAAAGGGTAGGTAGATGTAAAATAGGTGAAGAGTGGGGATCAATCAGAGGAAAGCCTA CCAAATGGGAAGATGGGTTCTCAGTCCGGTCCATGGATTTGACCTGTAGTGTGGCTTTCAGGCTTTCAGT TGTCTTTGGCTTAGAGGTGGGGTTTCACTGGAGACCCGCCCCTGTGAGGCATTTGTCTGCCTCCTGCCGC TATCAGTGTGGGCGAAGTTTCTCTAGAAACCACAGGGATAATGCAGTGTCCACAGCTGGTAATCAGGTTA CCACCATGAGGCCTACGACAGGGAGAAGGAAGGGGGAGGAGTTGCCCAAACCTGGAGAAGGAAAGGACTT ACTTTCAATTGAGAGTCCAAGACTGTCCACAGACACTCTCAGGGTGGGAGCTGGGAGAATGAATGCCCTG ACCTGACCCTCCCTTCGTCTGACCTTCTGCAGGCCTCCCCATTGATTAATAGCACTGGGAGCCAGAGAGT GAGGGAGCCTGTTGATGTGGTTCTTACAGAGCCAAAAAGTCAGAGCAGGCTGGGCACAGTGGCTCATGCC TGTAATCCCAGCACTTTGAGAGGCCAAGGTGACTTGAGGTTAGGAGTTTGAGACTAGCCTGGCCAACATG ATGAAACCCCGTCTCTACTAAAAAATACAAAAATTAGCCAGGTGTGGTAATCCCAGCTGCTTGGGAGGCT GAGGCAGGGGAATCATTTGAACCCGGGCGGTGGAGGTTGCAGTGAGCCAGGATTGCACCACTGCACTCCT GCCTGTGCAAAGAGTGTGACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGGCAAGAAAAGCAAGGTGT AACTGGATCTGGAGAGACAGATGGAGGATACCAGCATAAGATTGATACCTGTCTTTGTTTTTTGGAGACG GAGTCTCACTCTATTGCCCAGGCTGGAATGCAGTGGCGCAGTCTCGGCTCCCTGCAACTTCTGCCTCCCA GGTTCAAGCGATTCTCCTGCCTCAGCCCCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCGTGCCCAGA TAATTTTTTGTATTTTGTAGTAGAGACAGGGTTTTACCATGTTGGCCAGGCGGGTCTTGAACTCCTGACC TCAAGTGATCCGCCTGCCTTGGCATCCCAAAGTGCTGGGATTACAGGCATCAGCCACTGTGCCCAGCCAA TATAGCAGTTTTTCTAAAGCAGTTTTCAGAAAAAAAAAAAAAAAAAATCAGTGGCCGAGAGGAAGACCAC TGAGCAGCATCTCATCACCAAGTCCTTTTGATTCTACCTCCAGAAATACCTCGACTCTCTCCTCTCTACC GCACTGCCCCACCCACCTGCACCTCCTTGCAGTTCATCTCACAGTCAGCCAGAGGAGCTTTTGAAAAATG CAAACCTGAATGTCACTCTCAGCGACTTCTGATGATTGTAACATATAAGCTTGAGCTTCTTAATTTGCAT ACTGTGGTCTTCTGCCAGACCACCCACAGGAGAGCCTTTGATCTCCCTTCAAATGTCACTGGCTTGGGGA GGCTTTCTCAGGCAGCCCCCACCCCGAGACTAGTTTAGGTCCCTGTGTTTTCTGCTCCCTGACCCTGTCC ACTAGCTTGAATCCACATTTGCAGTTTGTATTGTCATTACCTGTTGAACTCTCTGCATTCGCCTCCACCC TGGGGGTGGGGGTGGGGGTGGGGGTAGGGACTTGCCACTCTACCCCAGTTCCTCTTCCTCTGTCATGTGA TTATAACAAGCCTTTCCCGATTTGGAACTAGATTAACTGCTTCAGAAGTAGAAAATGCATTTGGAACTAG CTTTTTGAGTTGGAAATTAACGGTGTCCTGGTGGGAGGACCCCAGCCTTGAGTTTTTCAGTCCTGTATCC TTATGCACACGTTGGTGAATAGTTCTGTGACCAACATTGCTTTTTCTTCTTTCAATAACATCCTCTGAGG TGGCTCTTGGGTCACAGAACGACTGAAAATCGATCAGTCCTTTCATTGACCCCTTGAATCATAGTCTTAC GTGGAATTAAATAAACTCTGTTGTCGGGCGGGGTGCGGTGGTTCACGCCTGTAATCCCACAACTTTGGGA GGCTGAGGTTGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTC TACTAAAAATACAAAAAAAATTAGCCAGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCAGGAGGCT GAGGCAGGAGAATGGGATGAACCCAGGAGCGGAGGTTGCAGTGAGCCGAGATTGCGCCACTGCACTCCAG CCTGGGGGACAGAGCAAGACTCCATCTCAAAAATAATAATAATAAATAAAATTTAAAAAAAAACCTCTGT TGTCATTAATTTTCAGGGTAGAGGTTTGAGCTCCTGTTTTCTGCTTTATGCTGAGGCAGTGGGAAGTGAG TGGAGACCTTAGAGGGTGGAACTGACACACAGGAGCGGGTTTGCCTGTTAGCATCACAAAACATGAGTAA CAGCTGCTCCCCCAGGCGGGGGGGTTGGGAGGGGGTGTGGGGGGTTGGGGAGGCTTTGTGTTTTATTTTT TGAAGAGAGGAGTGTAGGATTTCATGTAAGATTAAAAGCCTCCTTCTGTTAGTGAAAGGATGAAAAGGAC AGTTGCTAAATATGTGTCATTAAAGTAAAGAATTAGCTACAGTTGAGGCCGAGCGCGGTGGCTCAACACC TGTAAATCCTGGCACTTTGGGAGGCCGAGGCGGGCAGATCACTTGAACTCAGGAGTTCAACACCAGCCTG GCCAACTTGATGAAACCCTGTCTGTACTGAAAATATAGAAATTAGCCAGCTTGGTGGCAGGCACCTGTAA TCCCAGCTACTCAGGAGGTTGAGGCAGGAGAATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGA GATCACGCCATTGCACTCCAGCCTGGGCAACAAAAGCAAGACTCTGTCTGAAAAAAAAAAAAAAAAATTA GCTACAGTTGAGGTTATTTAGGTTATTTCCAGTTAGAAGTTCTGATACCATTAATAAATATTTTACCTTT AAGCTAAAAGAAGCTTAACCAGTGTTTTAGTTAATAGCAGCCAAACAACAATCTGTCTACTTGCAGAGTC TGCCATGTTCCTTCTACTCACAGTCCACACAGACTAAGCAGAGCTAAAGATGCAGACAGGGAATAACCAA GTTCACACTTCATCTAGGATGTTTTCCTGATACCCCCTAACCTGGAGTTAAGTCATCGTCTTTGGTGTTT GGAAGTCAGATGTTTTCTATTGAATTGATGCCTACATAGTACCCATAACTCCCCACTCCTGACATTCGTC ACACTGTGATGCACCTGGCAGCTTTCTAGTCCCCTAAGCTCCTTGGGAAGGGTATCCATTTTATCCTCAG TTCACCTAGCCCAGGGCTTGGTGTTTGTCTAGTACAGGTCATCATATGATTGTTGAATTTTTCAAATACA CAGATTTTTCTTGAAACCTCTTGATCTCTGTGTTGGTCTCTTCCTGCCCCCTCCCTTCCTCTCCTTTCTT CTCCCTGCTCGTGCAGTTGAAATTCTGACATTCCAAGAGCATTTCAGCTCCACCAAATAGGACTTCCACA TGTCACAAAACGCAAGACAGTTATTTTGAATGGAAACTTTTTGTACCCCTTTGGTAGAAGTTTATTTTGG GGTTTGTCTATGCATTTAGGTTTCACTGCCTCCAGATTTATCTGGGTGGAGTAATATCACATAAGTGTGA ACTACCTTCCTGTTTTGTTAAAAATATCAAGAGCAATTTCTCTTGATGATAAGAGGTCAACTGAAGAGGT TGATGAGCATATCCTAGTTATCTTTTGAACTAAAATATTTCTCAGAGAAAGAAATATCCTGTAATTTGGT TAGTCGTCTTAATTGTTCATCTTCTAACATGTATGAACATTATAAAGAAACTTTTTTAATACATGAATAG TCCTGGTCTCTTAATGTGATCATTTTTCTCCATCAGCCTAGTTGCTGGTCAGTGGGTGAATCAAAAAATC CAAGGTCTTGCAGACTGTTCCATAAAAATTTTGCTGGCAGAGTTGTAGCTATTAAAATTAGCACCCTGCA AAAGTCTGTCACAAGTCAGACAGGCAGACCGAATCAGAATTAGACATCACATTGCCAGGAAGCGCTCCAT CCTGAGAGGGATTAATAGGACATGTGTAGAAACAGACTTACACCTCCTCTCTCCCTGGTCCAGCCCCCTT TATCCCTGTCATACTGAAAGTTCCCTGCTCTACCCACCCACCCCCACTCCTTCCCAATCTTATACCTTTT TTTTTTTTTTGAGACAAGGTTTCTCTCTGTCACCCAGGCCGGAGTGCAATGGTGCAATCACAGGTCACTG CAGGCCTCGACCTCCCAGGCTCAAGCAATCCTCCCACCTCAGCCTCCTGAGTAGTTGGGACTGTATGTGC ACACCACCATGCCAGGCTAATTGTTGAATATTTTGTAGAGACAGGGTCTCCCTGTACCCTCTAGGCTGGA CTCAAACTCCAAGGCTCAAGGCATCCTCCCGCCTTGGCTTCCTGGAGTGCTGAAATTTTACAGGCGTGAG CCACTGCACCCAGCCTACTTAGACAAAGAAGTAGGTGGCCTTGTGGAAAGGTACTCCACATGGCCTTTAG GCAGGGTGCTTACGTTACAGGAAGACTGATTGTTTAATTCTCTTACCTCCTTTACCTCTCCTTGCTTGGA TCAACAAACTCATGGCAGTCTTTCTAGGATCTATTTAAGAGGTTCTTGTTTATCACCAAGAATGTATAAA TTGACGGTGCGGTGGCTCATGCCTGTATTCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATCGCTTGAGC CTAGGAATTGGAGAACAGCCGGGGCATCATATGAAGACCCTCGTCTCAATTTTTTATTAAAAAAGAAGAG AGAGAATGTATAAATTGTTGTAGACCCAGCTTGCTCTAGGGCACTAAATGTATTACTTAGAACACTTAGA ACAAAGCCCCCACATATAAGTCAGTTCCCCAAAATATGCTAGATACCATACTAAGAGCTGTGAGGAAGAC AAATGAGAACTGGGTATGGAGCCAGCTTCATTGCTTGCGGGTTAGTTTGGGAGGGGGCCAAGACATAGCA GCACATGGTCCAAGTAGTGATAGACCAGATACCATAAGGGATTATATTATTGACAGTAATCCTCCATTAA ATACTATAAGATTGAAGCAGAGGGAAAGGTGACCAGGGTGGTTGTAAGCTCTGAACTGAATTTTGAAAGA TTTCAGTAGACAAGGAAAAGTACAGACAAGCGGTGGGGAGGAGTACAGTGTGTTTAGAGGTCGGTGAGTT GACTAGCTGACTGCACGGCAGGGCTCATTTGGAGAAGCAATGGGAGATCAGAGCAGAGAGTCGATGATGG CCAAATTATGAAAACTGGAATGCCAGACTATATTTGCACTTGTAGAAGGATACTTACGGCTTTTTAACAG AAAAATTATGGTGGTTAACTTTGGAGCACTTAAGCGTTGTTGCCTGGACATTTGGTGGGTCCCCATCTCC TGACTCACCAATGTTTCCCTGTCACACTGATCCCCACTTTGAGCAGCTACTTTTCAGAAAGGTTGCAGTT GGAAAGAAAGCAGTATTCATGGGGCACAACTCCTTCCTTCATAGGCAGAGGGAAGTATAAAGTAATGAAT GATTTTTACCGTGGAAAGTTGGAGTTTGGGGACTTTGTCCTCCTCCCTGTCTTTCCTTCCTCCTTCCCTT TTTTTTCTTCTTTTCCTTTAAAAATGTTTAAAAGGTGCTAAGTCAGAACCTCTCACCATTCCATCACCAG GGGTCAGGAGGTATACCTGACTAACAAATACCCTTTGTTTTTCTTTTGTGTTTTTTTTTTTTTTTTTTTT TTAATGGAGTCACTCTGTCACCCAGGCTAGAGTGCAATGGCGTGATCTCGGCTCACTGCAACCTCTGCCT CCTGGTTTCAAGCGATTCTCCTGCCTCCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTAC AGGCACGCACCACCAAGCCCAGCTAATTTTTTATATTTTTAGTAGAGACAGGGTTTCACCATGTTGACCA GGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACTCACCTCAGCATGCCAAAGTGCTGGGATTACAGGC GTGAGGCACTGCGCCCAGCCAGGAGAGTTTTAAAACTTCATAAATGCATTTCATTTCTTCTCAACTTTCT GGTTGTTAAAAGCCAAGTACGTATCACCTGGCCTGGTTGGCGAAGATGCTTTTCAGATTTTTATTGAGCC GTGGCCTTGCTGTAGTTGCGGTCATTCCAAATGGAGACTGATCTGCTCGGCATATGTGAGAACTGTTCTC TCTGTGTTCCTGGGTGAGCAATTCAAGCTTTCTGTGGGACCAGAAACCTTAATTATTGAACTACCTTTGC TGGTTATCTCATCACTAAAATTGTTAATCGTTTATCTACACTGTGGGTGTTTTTCATGATTTGGCACACA GCATAGCAGGCAGCATTGCCAAGATGTTTTTCATGTTGCAGAAAAACTGTAACAGATGGAGGTGGTGATT GTGAAGCACTTATTTAAAGTGTTAGTAATGAATCACTATAGCTTGAAACTGAGTCAGTTATCCATACTAA GGGAAGTTGAAGAACATTCTAATAGCTTCTAATAAAATACGTAATCAGGCACCTGAAGAGAACTGACTTT GAGTGGCTCTCCCATTACTGTTACCCTAGCCAGGGCCCTTAGAATTTATTCTTAGGGGCTAAAGTCTTTT AAAAGCATGCATGCATGTGTGTTTTCTCTTTTCTAGGAACTTGAAATTATGTAGTAGATGTCACTAGAAT TCTTGAAATTTGTCTTCAAGTCATGGCAGTATTTCAGTATCGCTCCTTTGGGATTGCCTGAGTGATACTC AAGAGTTAGACTAGTTTTATCTGGGTTCTTTGAAGAACTGGGGACACCTCACTGGCTTATGTTGAATTTC TGCACTGCAGGGACCAACTATAAATGGTGTTTTTGGTTTTTTACGTGTTAAGAGCTTTAAAATGTAATTC TTCCTATCATTCATGCACAAATGTTCTCACACAAATTGCTTCACAGATTGATAAAACTTTGAATAATTTT TCCCTGAAGAAATGTTGAACTTTTCTGCAAGCTGTTGGAATTGGAGCGCGTGTTGAAAGGCTTGATGGGA CCATAACTGTACAGCCTATTTCTTTTAAAAAAAATTATGATTTCTATTTTTTATTCATTTACAGATGACT GAATATGTTCAGGCCAGAAAATATCCCCTTATTTCAAAATGCAGCAATCTATAAACAAAATACTTGCCAT TTTTCTAAATGACACCTTTTTCTATAATTTGTATAGAAAATTAAGTGCAAGGGCCAGGTGCCGTGGCTAA CGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCGCCTGAGGTCAGTAGTTCAAGACCACC CTGGCCAACATGGCGAAACTCCATCTCTACTAAAAATACAAAACAATTAGCCAGGTGTGGTGGCAGACGC CTGTAATCCCAGCTACTTGGGAGGCTGAGGCATGAGAATCACTTGAACCCAGGAGGCAGAGGTGGCAGTG AGCTGAGATGGCGCCATTGCACTCCAGCCTGGGTAACAAGAGTGAAAACTGAAGCTGTCTCAAAAAAAAA AAAAAAGAAAGAAAGAAAAAGGAAAATGTATATATCATTATAGGTCAGTGAACTTTCACAAACAGAACAC ACCCAGGTCAGGAAATGTGAGATAAACAGCACCTCTAGAGTTCCTTCATGTCCCCTTCCATTGACTTGTA CATATATATATATATTTTGAAGTAAACATAAACTCTTGGGAGGCCGAGGTGGGTGGATCAGGGGGTCAAG TGATCGAGACCATCCTGGCCAACATAGTGAAACCCCCTCTCTACTAAAAATACAAAAAAATAGCCGGGCG TGGTGGCGGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGC GGAGCTTGCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAA AAAAAAAAAAAAAACATAAACTCAGGATTTTATTGTCTTCATAATAAAACAAAAGATGACACTTAGAACT GGATCACTTGGCCCTTTCTCTTCTTATCTCCTCCCAGTTCAAAATGCTTGCATCTTTTAATAGCCAGCAT TCTCTTAGATCTGCAGTTGGGCTCAACGCACTCAAGCCTTAGCACAGTCTTCTTTGTGGTTTCAGCCTTT TTCCGGAAAATCGACTTAGTCTGCCCACCATAGCCACTCTGCTTCCTGTCATAACGCCGCTTTCCCTGGG CATACAGAGAATCCTTTCCCTTCTTGTACTGTGTCACTTTGTGGGGTTGATGCTTGCCACACTTCTTAGA GAAAGTCCAGTGAATTTTAGGAAAGTTGACCATTTGCGTGAGTGCTATCAGCACAGAAAGGACTTGTATA TTTTTAATTCTTCTGTGTAAAGCTCACCTCATTCCTCATCTCTTAAATTTCTTCCTGATTTGGGCTCTTA ACATTATTTTCAGTCTCTTTGCAAAAAAAAACCAAAAAACAAAAAGAACTGTCTTCACTGAAACTTGTCT CTTCCTCCTCTTATAATCTCATCTCTTGATCAATCTGCTTCCGTTAAACCAAAGTGTCGTGTGGCTACAA AGTCATAACTCGAGGGAATATGGGGGTTGGAATAGAAAATGCAGCTGTGGGGTAATAGCTAAAAACATTC CTTGGAGATTTTAAAGCTGAAGGAAACTTTTTGTGAGCTCACCCGTGGATTTGTGCAGAGGGAGTGAATA AGCAAGTGAAGACACAGTGATGGGAGCAGCTTGCTCATGCTCAGGAGTCTGACTAGGCCTTTAAAAATTA TTTGTGGCCGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCAGATCACC TGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTATGAAAAATACAAAAATT AGCTGAGCATGGTGACAGGCGCCTGTAATCCTAGCTACTCAGGAGGCCAAGGCAGGCAAATCACCTGAGG TCAGAGGTTCAAGACCAGCCTGACCAATATGGTGAAACCCCATCTCTGCTAAAAATACAAAAATTAGCCA GGCGTGGTGGCGGGTGCCTGTAATCCCAGCTACTCGAGAGGCTGAGGCAGAGAATCACTTGAACCTGGGA GGCGGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCT CAATAAATAATAATAATAATAATAATAATAATAATAATAATAATAATAGTAGTAGTAGTAGTAGTAGTAG TAGTAGTAATAGTAGGCCGGGCGCAGTGGCTCACGCCTATAATCCCAGCACTTTTGGAGGCCGAGGCAGG CGGATCACGAGGTCAGATCAAGACCGTCCTGGCTAACACAGTGAAACCCGTCTCTACTAAAAATATAAAA AATTAGCTGGGCGTGGTTGCAGACGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCCT GAACCTAGGAGGCGGACCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGA GACTCCATCTCAAAAAAAAAAAAAAAATAGTAACAGTAATAAAATAAAAATTATTTGTGAAGGATGTGAG CTTTCACCTAAAGCCACAGCAAATGAAACAATCTTTGTAGGTGCAGCCTCATCCTCAGATGCTTCTGGTC TCTGCCACCTCGAGCTCTTCAACATTCATTTGTGTTCTTTGCTGTTTTGTTTTCTTTTTCTTTCTTTTTT TTTTTTAACCCGACACTTCAGTAGCTGTTTTGTATACTTAAACATTTGAATAAAACTTAATTTTTAAGCA TCTAATTACATCACTCCAGTTTCAGGGCTTGTGTGTGCAAGCTCCCAGTGCAGGTGGAGCAGTTGGGTTG AAAGGCCTGGTCTCTGGCTCAGGGTTGCAGCTGCATTGTTCATCCTGTGTTTTGCCTCCGGCAGAACCAA GCTTTTTCTGAAATTCTAGAGTGAAGAGGTTTAGAGGTATGTGCAGCAATACCTGGGCTATCTGATAACG TGATATTCTGGATACTAGAATTTTCCAGATAACCAAAATCGTAACCATTCATGTACTCAAATGTTACATT TTTGGCCAGCATGATGGCTCACGCCTATAATCCCAGCACTTTGAGAGGCCAAGGTAGGTGGATTGCTTGA GGCCAGGAATATGAGACCAGCCTAGCCAACATGGTGAAATCCCGTGTCTGCTAAAAGTACAAAAATCAGC TGGGTATAGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGCCGAGGCACTTGAATCACTTGAACCCG GGAAGTGGAGGTTGCAGTGAGCCGAGATCATGCCACTCCACTGCAGCCTGGGTGACAGAGCAACAGAGCA AGACTCTCTCAAAAAAAAAAATTACATTTTTAAAAGCATTAATTCCATATTTTCCTTCTTTCTGGGGGAG AAAAACATACTAAACACCAAGTAATAATTTTTGTTCTGTAGACAGCCATAGTTCTAAGTTGATGTCAAAT CTAGGAGTTGCCCTGGAGTTGTGTTTGTTGGGGGAGGGGACACTTTTTAGAGGGATTTGCCTCTGTCTTG GTAAAGGTGACAAGAAGAGAGTGTAGCTCTATGAACTCCTGGCAGGTAAATAGAGTTATCTTTTTCTGCA AAGTTATTGGTCACAAATCAAAAGTGTCCCTTTCTAATGATTACTTTGTTCTGTTTTGATGCACAAATAG GTTACAAGCAGCTCTTTGTCAGTCTGACTCTCTGTCTTCCAAGAACAAGTGTATACAGTAAAAGTAGACA CACCTCACCATTTCAGGAGTTAAGACATTTTCAAAAACTCTTCATAGCTGGTATGGGTGCACGCACCTGT AGTCCCAGCTACTCCAGCCTGAGCAACGTAGACTCTGTCTCTGAAATAAAATAATAAATATTGTTTATAA GCCTGTGGGGTTTTTATTATTACTATAGGATGATGCTTTATAAGGTCATTATTAGACCACATTTTCCTTC TAGACCTTATTTTTGGTAGATAACAGAATCCTGGCCTTAAATAACTTTTAAAGTAGCTCCTTTTCTCAAA GGCTATTCAGAGTTTTCTGTGCTGCCAGTACAGGGGCAGGTGGTGGTGGCCCGGCAGGGTTCAAGCGCAC TTTCCCTCCTCAAACTTGTCCTTGGTGTGTGCTTTATAATTGTCTATCAATACAGCACCATTGCTGGCTG CAGCACAATGCAGTGTTTTTAAAATGAAGACTTAAAAATTATGAGTGTACCTTGCATATATTGTTTTATC TCATTCCAGTCTTTGATGTGATTTTTTTACGAGAAACAAAATGATGACTAGAAGAAAGTTTTCATCAATA CTCTATCAATATTTATGTGACTCTTGGAAACTTTGAATACACTGGGATTTACCACTAGCTAATTTTTTTT GAGAGTTTGCTACACATATTTATTAGCTCTTTCAGGATTTATCACCTTATCCTAAGCATTGAAACCCAGT GTCTGGCACCTGCAGTCAGAGTGTGGTAAGCATAGCAGATAAGCACCAGCATTGCAAAGCTCTGCAGGGC ATACCCTCTGTTAAGAAAGCGTAGTCATTAATGCAGCCTGGCTAGTTGTCGATCATCTGTCATTCTTATC TACCCTTTCTATTGCATCTCACTTTGAATGGCAGTACACAGACAGCACTCACTTTAGAGCAATCCAGCTT CTGATTGGCTACGAGTACAGCATTGTTCAACATCTTGAATAAATCATTTTGTAAAGAATGTTACCAGTTT CCTCTCAGAACTTTGTTATGCAGTGTAGATTACCACTGTACTAGCCAACATTTTCCTGGGCCCACCATTT TGGGGTTGTATTCACATTTTTGTTTTATCTTTTACCAACTTTATGCCTTCTGCCCTTTGCCTTTTGTTGT AAGTCTAGAATTCATAGGGTGGCTTTCACGCTGTACCTGATTCTGTTCTGCTCCGTATATACTAGTCCCC CCTTACCTGCGGCCAGTTGCAATCCAACATATAAATAACATATTTTGGCCAATCGCAGTGGCTCACACCT GTAATCTCAACACTTAGGTAAGCTGAGGCAGGAGGATACTTGAGCGCAGGAGTTCAAGACCAGCCTGGGC AACATGGCAAGTGCCTATAGTCCCAGGTACTCAGGAGGCTGAAATGGGAGGATAGCTTGAACCCAGGAAG TTGAGATGCCATGAGCCGTGATGGTGTCACTGTACTCCAGACTGGGCAGCAGAGCAAGACCCTGACTCAA AAAAAAAAAAAAAAGATATTTTGAGAGATAACACATTCACATAAATTTTTATTACAGTATATTGTTATAA CTTTTCTTTTACACTTTTTAAATATAAAGACAGGGTCTCACTATGTTGCCCAGGCTGGTCCTAAACTCCT GGGCTAAAGCAGTCTTCCCACCTTAGCCTTCCAAACTGCCAGGATTACAGGTTTGAGCCAGCACACCTGG CCTGTTAAAACTTTTCTATTTTACTACTAGTCATCATTAATCTCTTACTGTGCCTAATTTACAAATTAAA CTTATAGGTAGGACTGGCATGGTGGCTCACACCTGTAATCTCAGCACTTTGGGAGGCTGAGGCAGGAGAA TCCCTTGAGTCCAGGAGTTCAAGACTAGCCTGGGCAAAATAAATAAATCGGCTGGGCACGGTGGCTCGTG CCTGTAATCCCAGCACTTTGGGAGGCCGAGTCGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGG CTAACATGGTGAAACCCCGTCTCTACTAAAAAATACAAAAAATTAGCCGGGCGTGGTGGCAGGCGCCTGT AGTCCCAGCCACTCGGGAGGCTGAGGCAAGAGAATGGCGTGAACCCGGGAGGCAGAGCTTGCAGTGAGCC GAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCTGTCTCAAAAAAAAATAAATAAATA AATCTAAAAAAAAATAAAACGTATAGGTATGTGTATAGTGTAGGAAAAAGCATAGCATATCTAGAGTCCT GTACTATCCACGGTTTCAGGCACCCACTGGAGGTCTTGAAACGTATCCATCATGATAAGGAGGACTACTG TATTACTCTACACATTACAGCGTCATGGCCTAGCCTATGCATGGCCTGGTACATGCAATTCAAGAGGCAG CATTGGAGAGAACGGTCATTGGAAATATGAAAGTCTGGGCATGATGTTAGCTCTGTGGGGTCACTACCTC GTAACCTGGGTTGACCATTGATCTTGTTTTTTTACATCTGTAGAATGCAGTGGTTCAGTTCCAGGATTTC CAAGGCATCTGCCTGAATTCTGCTGGTTGATATGCTTTCAGCACTATCTAACTTTAATACAATGTGGCAT TTGGGTTATTGAACTGAGTAGGATTTGCCATGCTTTTTCCTGAAAATAGTTTTCCCATACGAGGGCATAT GGTTGTCCTCACAAGCAGCAGTGTTCTGGAGCTGTTTGGTGGGTGACCCGTACTTGCGGTAACCCAGAGA AGCCATGAGGGGATCCAGGACTGTATCACTGTAGATTCTGGAGGTCGGTTGGAAGATCTCTAGAGGAGTC TAATAAAAGGTTCTGTTGCTGCTTAGTTCTGCTGTGACACCTCTCTCTCCCAGAAAGTAGACTTTGTCTT CGTCAGGCTCCCTTATTCTCCTATGTGTTTGCCATTTTCCAGAACCTCTTCTCCAGGTTTCTCTCTTAGA AAAACCAAACCAAACAAAAAAACTGGCCGGGCACAGTGGCTCACACCTATAATCCCAGCAATTTGAGAGG CCAAGGTGGGCAGATCACCTGAGGCCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTC TACTAAAAATACAAAAATTAGCTGGGCAACGTGGCATGCGCCTGTAATCCCAGCTACTCGGGAGGCTGTG GCAGGAGAATCGCCTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCGCGCCACTGCACTTCAGCC TGGGCGACAGAGCAAGACTCCGTCTTAAAAAAAAAAAACAACTAATACTTGCCATTCTTCTTTCTCCTTC CTTACTGAGGGTTTCATTCCAGATGTTTGGGAGCCTGAATTTTCATTTTCAGAGATAATTTCTGTTTCAT TTTAACAGAGTTTAACATAATGCTGGTTGTTTGAAGTTAAAAGGAGTCTTATATCCGTATAACTGATAAT ACTTCGAGTGAAACCGTTCACAGACCTAAAAGATAGCATAATTGTCTTGTAACTATCTTTTTAAAGGGAA AAGGAAATGATTGGGTTTTTTTGTTGTCTTATTTCTTTTCAGGTTTTGAACGAAGAATGTGATCAGAACT GGTACAAGGCAGAGCTTAATGGAAAAGACGGCTTCATTCCCAAGAACTACATAGAAATGAAACCACATCC GTAAGTTAAGCTCCATTAGTCTTGGAAGGGTTGGACCCACCTCCTTGTTTCAAACACTCTTTTTAAAATT GAGATCACTGGGATGGATGTCATACTTTTTATTCACGTTTCTAGGGAATTAACAAAGGATATTGATTGTG CATGTTAATAGTATATAATAATATATCATAGTCAATAATATTATATGTTTTAGATTGATAATAACTGTCA GTGATCTTCAAAAATAAAACGATAGTTGGTGCAGGTCCGTAATTCTTTTTCTGTTAAATATGTCTTAGAG CCAGATGTGTTTTATAATTCTGCATTTTTTTTGAGTTTTAGAAAAGGTACTTAGATGATTTTGTGTTTAT ATGTGCTAATGCTGTGGGACGGTATCTTAATATCTTTGTATCCCCAGAGTACGGTGCTTGGCATCTAATA GTTCTCAATAAATGTTTATCCCTCCATCTTAGTGTTCCTACTTACAAGAGAACAAAATATGCTGTCCTCC AGGCTGCTGGGAGCAGTGAATATTTTTAATTTTTTTTCAGAAGCTACCCTTGTCACGATTTTATTAATAA CGCAACATAGTGGACCCCTGAGAGCCCCTGCAGACCACTGTCCTCCCGTTCTCACCCACCCCTCATTCAC AGGCCCTGCTCCTAGCACAGAAGCAGTTGCTGGCTTGCCTTACAAGTGTGTCAGGGGAGCTGAGGCTTTC CACGCTCAGACTAGAATGCCCTTGGACATTGTCCACTTGCTTTCACAGCAGCTGGTGGCGGAGACTTTCA GGTGGCTTGTCGCATCTTGAGTGGGAGGGGCCTGTTGGATCACAGCACATCCTCCCCAGGTCCCATATAA GCCACATAATTTGTGTACTTCTGTTTCCTTCAGTCGTCCTCAAAAGAAACTGTAGGTCAAGGGTTGGCTA AACTTTTTCTGTGAAGAGCCAGATAGCAAGTAATTTCGACTTTGTGGGCTGCATACAATCCTGTCAAATA TTCCTTGTAAAAATTTTCTTTTAACAATCGAGTAGAAATTTAAAAAACAGTCTTAGGTTGTGGGCAGATT TGGGCAGAAGGCCATTATTGTTTGCTGGCTCCTTCATTAGATCCAAACACAACATCGACTTCAGTTCCCT TTTGTTTTCATATTTTCAGATTGAAAGGGAATTCAACAGAACATCATACTACACTTCTTATATGACATGC CTGTGGCTCGAAATTCTTATTTTTCTTCAGTGTTTCGGGTGACACAGGCATTTAAATCTGACTGTTGAGG AAAGATAGGAAAGGCTACCTTCCTTGGAAAGTTGTAGTTACTGCCAGGCTGACTGGGACAGTCACTCCCT TGCCTTGACCTTTTGTCCCCACTATGAAGAACTTTAGAAGAATTGATGGAGAAGCACCCAGCACAGGCTC AGCTGTGTTGTTATTTGCAGACTCTGCCCAAAGGGTGGGCAGTGCTCAGCCACTCTGAGCTCTGAAAAGG CAACTAGCAACTTAAAAACCCTTATTTATTCAGGTCTACCATATTGCTAACAAAGACCATGCTTGTGCCT ATGTAGGTGTTTGGCCTTGCAGACGTAGTTGCTGTTGTATAGGGCTGCTCTGTGGCTGGATGTTCATGAG TATAGGGTCAGGGTCAGTACCAGGCCTTCTCCTCCACATCCTACCACCTCCTGTTTTTTTGTTTGTTTGT TTGTTTGTTTGTGGGGGTGGGGAGCAGGGGTTATGGAGGAAGAGGGAAGCATAAAATGTAGCACCATGTC AGCTAATGCAGCATTCAAGTTAACAAATTAGACTACAAAATGATTGTTGGCATTAGTGCTGCAGCATGAG TTGTATATGCTTGAGGGGTGGATCCAAATATGTGCTTTTCACACTAAATGCATATGGATGGGAGCCTACG GGATGTAGTAAAGAATTATATTGGAAAATTAGCCTTCTCCCCTCACCCCCTTAGCTCTCGCCCTTGCTAT TTCTGTTGTATAAGCCCACCTTTTTTTTTTTTGTTTTTTGTTTGTTGTTGTTCTTGTTGTTTTTATGAGA CGGAATCCTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCTATCTCAGCTCACTGCAACCTCCGCCTGC TGGGTTCAAGCGATTCTTGTGCCTCAGCCTGCCGAGTAGCTGGGACTACAGGCGCGTGCCTCCACTCCCG TCGAATTGTTGTATTTTTAGTAGAGATGGGGTTTCACTGTGTTGGCCAAGCTGATCTCGAGCTCTTGGCC TAAAGTGCTGGGATTACAGGTGTAAGCCACCGCACCCTGCCAAAGCCCATCTTTTGTTTGTTTGTTTGTT TGTTTGTTTGAGATGGAGTCTCGCTCTGTCGCCAGGCTAGAGTGCTGTGGCGCGATCTCGGCTCACTGCA ACCCCCAACTCCCTGGTTCAAGGGATTCTCCTGCCTCCACCTCCTGAGTAGCTGGGATTACAGGCATGTG CCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACTGTGTTGGTCAGGATGGTCTC AATCTCCTGACCTCCTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCAC ACCCGGCCCAAAGCCCATCTTTTTAAAGACTTTCAAAACATTTGCCTGTTAGAGCTTGCAGCAAGCCAAG ATCACGCCACTGCACTCCAGCCTATTCAACAAAGCAAGACTCTGTCTCAAAAAATAAAAAATAAAAAAAA TTCACCCGTAAGCATGTAGTCACATGTACATATCATCATTTTAAAAAGTCAAATTTATAAATGATATAAA ATGCTATAGAAATGTAGAATGGTGGTATTTCAGTGTTTTAGTAGTGACAGCTATTCACAGGGTCTTGCTC TGTCATCCAGGTTGGGCTCAAGTTATCCTCCCACCTTAGTCTCCTAAGTTGCTGCGTCTACAGCTGTGCA CCACTATGCCTGGCTAATTTTTTATTTTTCGTAGAGACAGGGTCTCACTGTGTTGCCCGGGCTGGTCTTG ATCTACTGGGCTTAAGCAATCCTCCCACCTTAGCCTCCCAAAGTGCTGGAATTAACAGGCGTGAGCAACT GCACCTGGTGCCAGATTTTTTATTTCTTGATCTGGGTGCTTATAACAGAGTTGTGGTTTTTTTGGTTTTT GGTTTTAATTCCAGTTAGAGTACTTTTTAAACATTATAATTTGTACTTCACTACAATTTATTTTTTTTAA TTGAAAATAAAATTGCGTTAATTTTAAGCTGGGGGCAAGAAAACACAGCAGCCATGTCTATGTGACACCA GACAGAAAGGTCTGGAAACCTAAGTGTTAGAACCGCCAACACGTGCTGCCTCTGGGGAGTTTGAGGGAAG CATCTTACTTTTTATGTTTGCTTCATGTACATCTAGGCTATTTCAGTTTATATTCATTATTTTATACCTA CAAATGGGAAAAAACCTCCCTAGTGGAGAGATCTTGGGGGCCTAGGAGGAAAGAGAGCCTTGCTGATTGA GAATCTTCACCCTCACCATTGCTATTGGAAGTGGCAGTGGTGGGGAGTGTGGGGCAGTGTGGGGAGAGCC AGCCGAGGCCATGTGTGGATTTTCACTGCTGTACCCAGTCAGATGCATGCTGCATACACTTATATTAGAA ACCCAGGGCCCCCCGATATGAGAAGGTTTAAATACCGTTGATTGGGGCCCCCCGATTGAGAAGGTCTCAA TACCGTTAAGTGTCCTTATTTATTTATTTATTTATTTATTTATTTATTTTTTGAAAGCGAGTCTCGCTTT GTCGCCCAGGCTAGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCAGGTTCACTCCAT TCTCCTGCCTCAGCCTCCTGAGTAACTGGGACTACAGGCACCTGCCACCACGCCTGGCTAATTTTTTGTA TTTTTAGTAAAGACAGGGTTTCACCGTGTTAGCCAGGTTGGTCTCGATCTCCTGACTTTGTGACCCGCCC GCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCGGCCTATTTAATTTTTTTGAG ATGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGATCTCGGCTCACCGCAACCTCTGCCT CCCGGAGATTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGCGCCACCGCG CCTTGCTAATTTTGTATTTTTAGTAGAGATGGAGTTTCTCCATGTTGGCCAGGCTGGTCTCGAACTCCTG ACCTCAGATGATCCGCCCACCTCGGCCTCCCAAAGTGCTGCGATTACAGGCATTGAGCCACCGCACCCAG CCTCCTTTTTTATTTTATTTATTTATATATTTTTTTGAGACAGAGTCTCACTCTTTCGCCCAGGCTGGAG TGCGGTGGCACAGTCTCGGCTCACTACAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCT CCCGAGTAGCTGGGATTACAGGTGCCCACCACTGTGCCCATCTAATTTTTGTATTTTTGGTAGAGAGTGG GTTTCACCACGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATTCACCCCACCTCAGCCTCCCA AAGTGCTGCAATTACAGGCATGAGGTACCGGGCCCAGCCTGTCCTTTTATATTTAGAGAGCATTCTATTC TAGTGATATGTGATTTCTCTTGTGTGGCCTGATTTCCAGGCACTGCAGGCCCTAGCCTTGAGTTATTTGT AGAAGCAGGAGGATCTATTGTCCCAGCTCCTCAGCATCCTGGCAGTAGAGTATGCAAAATGAGAAAGACT CCAAGCAGGTAGATGTCAGACTATTCAGAGTTACTAAGAGTCCCTAGAGGCTGACACACACACACAAGGA CAAAGTTACTAAGGGCAGCTTCTAAGTGTATCCTTCCTAGCAGATCACATCTTTCTGTTTGAATTTGAGT ATAGTATATTATTTTAGGTACATCTTCCAATATGGTTGCTTATAAGTAAGATATGTAAATTAGCCGGGCG TGGTGGCTCGCGACTTTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCTCGAGGTCGGGAGTTCA AGACCAGCCTGGCCAATATGGTGAAACCCCGTCTCTATTAAAAATACAAAAATTAGCTGGGCGTGGTGGT GGCCGCCTGTAATCCCAGCTACTAGGGAAGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGAAGGTT GCAGTGAGCCGAGATCGTGCCACTGCACTCCAGCCTTGATGACAGAGTGAGACTCTATCTAAAAAAAAAA GGGCCGGGCGTAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCAACAAGG TCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCATCTTTACTAAAAATACAAAATATTAGCC GGGCATGGTGGCGGGCGCCTATGTATAGTCCCAGCTGCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATG GCGTGAACCCGGGAGGCAGAGCTTGCAGTGAGCGAGATCGTGCCACTGCACTCCAGCCTGGGTGACAGAG CTAGACTCCTCAAAAAAAAAAAAAAAGAAAAGATATGTAAGTTAGATTTACAACTTTAATGGACTATTTG GTCCATTAAAAGGACTTTTGATATTATAATTAGCATATTAAATGAATGCCAGTTTCCATGTTTATAGGTC TTTATTTGCTATAACTTTTGCTTTTAAAAATGATAACTAAAGACAATTTTGAGAAGAGAACATGGTTTTC ACAGTTTCTTCTTCCTAATTATAGTTTTCATTTGAAATAGTGAGGCAGCTTGACTTGAAGCTCTTGTAGA AGTGTTCCTCTCCTCTTCCTCTTGATAAGCCACAGCCAGTTGCTTCACAGTTTTTCATGAATTTAGCCAC TTTTTCTTCTGGCCAAGGTGAATCAGCAATTGGGAGCAGAAGAGTCTGCAACTTGCCTCAAAAATCTGAA TTTTGCAGCTAGCTGCTGAGCATATGGTAAATTACAATATTCCTGGTGGCTTCTGAAAGCTGAACTCTGA GCAGTGGCCCCAGAGGCAGGCCTTGAGAGGAATGCTGACCTTAGTTACTGGTAGAGGCACCCTCATACTA TCTGAACCTTTTGCCTTTGGGCTGTTAGCAAAAGTAACCCTGCCTCCAGCTCCTGGCCGTCCAGGTTTCC TCCCCACTTTCCCTTAGTCCCACTGTGGTGAAGCTGTGATCTTATCACATGGCTGCAGGAAGGGGCCAGT CTCTCCTTGGCAGTTCATCCCGTACACCAAGCCCAAAGGCCTGAGCTTTTCCCCAGGCGCCTTTGTCATG AGTCAGTAGGGAGTCCAGTGGGCTTTGGCCTGGGGGGCCCATTTTCAAATGTCTCCCTCTATAGAAAGAG TGACCCACGGTTAGTGCCTTGGTGAGTCGCTTTCTGGGAAATGGAGTAGGCTAAAGACCTTTGAAGGTCC ATCTCTGGGGACCCAACCCAGTGTCGATCTTGGGCACTGTGAGGCTGGAGGATGAGGAGGGAGGCCCCTT CCTCTGGCAAGGAGTGTTGTGTTACTCACATTTTGAAGGCTGGATATCCCGTTTCTTTGTGGGGAAGCAG ATGTTGACCAGCTTGCCTTCCTTCCTTAGGTGGTTTTTTGGCAAAATCCCCAGAGCCAAGGCAGAAGAAA TGCTTAGCAAACAGCGGCACGATGGGGCCTTTCTTATCCGAGAGAGTGAGAGCGCTCCTGGGGACTTCTC CCTCTCTGTCAAGTAAGTATTTCCTGCTGCAGTTGCCTGGAATCCTGTCTCTGACTGATCCAAATTGTGA AGCCGTTGGTCAGGTGCCTGGCTACACACAAAATGGTGGAGGCTTAGCCTAAACAGTTTCTTCATTTCAC ATTAAAATCCTAATTTCTGGCTCCTCTCAAAATGAGTTCTAGAAGCACTGGATGTAGATTCCCATGTGGA CACAGCCTTCAGGAGGTGAGCAGCAGCTCCCTGCAGCCAGCTGGAGCCTGCCAGTTTTCCCTAGTGCCCA GCACTCCTGAGCTTCTGCCCTCCAAGGGATTCCCGCAGCTCTCTCTAATGGGATAGTGGAGCGCCTGTCG GCTGCCTTGGCTTGCCTTGCTCAGGTCCACTGACTTAAATCAACCAGCCCCATCCTAGGCCCTCACAGTC ACTTAAGAAGGCTGCTGCAGGGGATGTGGGGCTTGCATTTCCCCGGTGGAAAGTTCAGGTGTGAAAGGGA GCGGGTAAGCAGGGAATGGAGAAGACAGGAAGTTCTGCCGCCATGGAGAGTGTGGAGAATAGAAACCAGC ACTTGAAGATTCTAAACAATTCACACCTCAGCTGTGAAGTCGGGATTTTGAATTAAATTGTTATTTCCAT GTTTTTTACTTTCAGTTATTTTCTAGTTAATGTATTATCATAGGACCCTCCCCAGGAGTCCGGCAGATCA CTTCATCAGTTATATATAAAGAAGTAATTAGATTCAACACTCAGATCACTACTTAGTTTAGATTACATTA AGATTGTTTTGTTTTTGAATGGGGGATAGAAAACCATTTTCCTTTTATTTTATTTACTTATTTTTGAGAC AGAGTCTCGCTCTGTCCCCCAGGCTGGAGTCCAATGGCATGCCTCAGCTCACTGCAACCTCCACCTCCCA GGTTCAAGCAGTTCTCCCTGCCCCACCCTCCGAGTACCTGGGATTACAGGTGCCTGACACCACGCCCGGC TTATTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCATATTGGCCAGGCTGGTCTTGAACTCCTGACCTC AGGTGATCCACCCACCTCGACCTCCCAAAGTGCTGGGATTACAGGCTGGAGCCACTGCTTCCAGCCACCA TTTCCCATTTATAACTGATGTAAAGCGTGAGACTTTTCCATTTCAAAAATGAACTGACCAGCCTGGCCAA CATGGTGAAACCCTGTTTCTGCTAAAAATAGAAAATAACCCAGGCATAGTGGCACACACCTGTAGTCCCA GCTACTTGGGAGGCTGAGGCCAGAGAATCATTTGAATCCAGGAGGCGGAGGTTGTAGTGAGGCGAGATGG CGCCATTGCACTTTAGCCTGGGCGAAGAGCAAAACTCTGTCTCCAAAAAAAAAAAAAAAAAAAAAAAAAA AACTGGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCACCTGAGG TCAGAAGTTCGAGACCAGCCTGGCGAACATGGTAAAACCCTGTCTCTACTAAAAAAAAAAAAAAAAAAAA AAATACAAAAATGGCCTCGGCGTGGTGGCGTGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGAGAGAA GAATCACTTGAACCCGAGAGGCAGATGAGCCAAGATCGTGCCACTACACTCCAGCCTGAGTGACAGAGTA AGACTGTGTCTCCCAAAACAAACAAACAAACTGAATATCTTATTTGGTTTTAGAACCACTTAATGTGTGA TTAAAATGTAGATTTTTTTTTTGAAACGTAGATTTTAAATTTATAGTTGTGGCCCGGCATGGTGGCTCAT GCCTGTAATCCCAGCCCTTTAGGAGGCTGAGGCGGGCCGATCATGAGGTCAGGAGTTTGAGACCAGCCTG ACCAATATGGTGAAACACTGTCCCTACTAAAAAAATACAAAAATTAGCCAGGCGTGGTGGCACATGCCTG TATTCCCAGCTACTCCGGAGGCTGAAGCAGGAGAATCACTTGAACCTAGGAGGCAGAGGTTGCAGTGAGC CGAGACTGAGCCATTGCATTCCAGCCTGGGTGAAAGAGCAAGACTCCATCCATCTTTAAAAAAAAAAAAA AAAGAAAAGAAAAACATGTGTGACACCTGTCTTTCTTTAGTTTTATACTGACCCAAGTGTAACTGAAACC TTATAAGATGAGGGGAACAAGCAGTAAATCACTGGGTGGTGGCCAAAACCACGGGGGCAGCCACGTGCTC GGCTGGACGCTGCCTGTTTGCTCAGCAGAAACTCTCAAACTTCCATTTTCTCAAGTAGAATCTTTTAAGG ATTTAATGCATTTATTGTTTTAGAAGCAAAGCAGGTGTCATGACTCTCTTTAACAACACACACACCTCTG CAAAAAAGGTTCAAGAATCAACAGTTGTCAGATGTTTCTTAGTTTTAGGATGTTTTGAGCCTGTGATTTG AAACACTGCTCATTATTGGGGCCCTGGGCTCTTAGAAACCACCTGCATTGCATGGGTGGAAGTGGGCCTC TGTGGGGCCAGAAGTGCCGTGGAATATACCCTTGCTAATGAAGCTTTCTCACCTTCCACATTTTGTCTTA ACATGTAAAGCAGTATTTTTTCCAAATGCGAGGCATCTTGTGCTGAGTGGCTTCCTTGAGGCTCAGTGCT GCCACCTGCCGGATTGATTTTCTGAAGCCTTTGGTTTCCATCAGCTGAAAGACTGAAGGAGAGGAGGGAC TCATTCATTCATTGAACAAGCACTCTCAGAGAATGCCTTTTTTTTTTTTTTTTTTTTTAATGAGATGGAG TGTCACTCTGTCGCACAGGCTGGAGTACAGTGGCCCAATCTCGGCTCACTGCAAGCTCCTCCTCCCGGGT TCACACCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGTGACTACAGGCATCTGCCACCACACCTGGCTAA TTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCATGGTGGTCTCGATATCCTGACCTTAT GATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCATCCGGCCGAGAATGC CGAGAGTGCCCGGCCAGGTGAACAGGACAGGCAGAAGCGCCCTCGCTAGGCTGGTGTTTTAGCCAAATAT CCTGTGACAGACCCTGTGAGCTAGTACCAGCCAGCCACGCTGTTGCCGGTTTTGCTTGCCAGTATAAAAG GGTGTGATCTAGTGATGGAGAAGCTTTTGGGTTTTGAAGTCTGGGCCTCTTTTATTGTCCCAGTACGTCC TTTTGTTCAGAGACCTTTTCCCCATGAGTGGAGCTAAAATTCCTGAATGGAAAACATTACTTTGAACTAT TCCCAGTTACGAGAGAATTGTTGAAAGTATTTCCAGCCCTCCTCACCTTCTTCCTGCATATAAGATTTTA ATTATTTTTTTATTCAAAGGATGTTAAGTCACACTCCTTTGTCTTAAGTACGGCTGTTTTTATTTGGTAG GGTTCAGGGCACATGGACTCTTTTTTTTTTTTTTTTTGAGACAGAGTTTCACTCTTGTTACCCAGGTTGG AGTGCAATGGCGCGATCTCAGCTCACCACAACCTCGGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGC CTCCCGAGTAGCTGGGATTACAGGCATGCACCATCATGCCCAGCTACTTTTGTATTTTTAGTAGAGATGG GATTTCTCCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTGCCCACCACGGCCTCCAA AGTGTTGGGATTACAGGTGTGAGCCACCGCACCCGGCCTGGACTCTTTATCTTACAAACATCTTCAGAAT GAGAATGACTGATGGCCTGTCCCTCTCTGGTTTCTGGATGTTGTCCTGGTGCCCATCATTCATAGGGAGA GGTCCGTCCCAGGGACACCCAGTGAGGAAACTTGTTGCTCTGCAGTCCCTGAGGAGTGCTGCTGGGACAG TGGTTCTCTCGAGATAGCTCCTATATGGAAATACCCTCGATTTGCCAAGTTAGAGCCTTTAGCCGGTCAC ATGTGCTTTCTGTCCCTCCCAGGTTTGGAAACGATGTGCAGCACTTCAAGGTGCTCCGAGATGGAGCCGG GAAGTACTTCCTCTGGGTGGTGAAGTTCAATTCTTTGAATGAGCTGGTGGATTATCACAGATCTACATCT GTCTCCAGAAACCAGCAGATATTCCTGCGGGACATAGAACAGGTGCCACAGGTAAGCCTCATCAGGGTGA GATGGGATCATTTTTAGTTAAGAATAGCTCCTCAGTGTGCATTCCTGTAGGAAAGGGGAGGCGCCCCTCA ACATGCGGGCGCCCTTCAGGGATTGCCGCTGGGGCTTCTGTGCTCCTTACTGAAAATGTTACCCTCCATT CACACTAAAGAGTTCTTTTTTCTGGCCCAGCATAGTAGCTCACACCTATAATCCCAGCACTTTGGGAGGC CGAGGCAGGCAGATCTCTTGAGGTCAGGTGTTTGAGACTAGCCTGGCCAACATGGTGAAACCCTGTCGCT ACTAAAAATACAAAAATTAGCTGGATGTGGTGGCGCACACCTGCAGTCCCAGCTACTCGGGAAGCTGAGA TGGAAAAATTGCTTGAACCCAGGAGGTGGAGATTGTAGTGAGCTGAGATTGCACCACTGCACTCCAACCT GGGCGACAGAGGGAGACTTCATTTCAAAAAAAAAAAAAAAAAAAAAAAAAGATTTGTTGTTTCAAATACA AGGTTTTTGCTTTTCCAGAGGCAGTGTGTAGCCAGCTTGCCAGCCTCTCTAGGGAGATGGTCTTTAACAC ACCCACCCAAAGATCCTGTCCCTGGAAGCAAATTATGAGGAAAACTATGCTTGTGAGGGAATGGGGTCGG CACCCGTTCCTGTCCCTCGAGCCCTGGTCGTAAGTTACGGTTAGAGCCCCTTATGTTATTCGAGCTCCAG AACTTTAGGCTTTAATACCTTAAGGGTGTCGTAGAAGGGATTTGCGATTCTGGGCCCACGGCCTAAACAC AGATGGCTGTTTCTGAAGAACTTTCTCCTCCAAGCACTGCCTGCCCTCTACTTGATAATACGGCACAGTT GGCCACCCTCCTCTGGGAGACATACTCTAATATTTTCTGAGCACTGGGAAATATCACACTAAACCCGCTT GGCCTGTAAACTTAGAATAGGTAAGAATAAACGGGGGGTTGGGAGATGGGAGGTGAGTTTAAGAAACATG GAGAATTTGGCACGCATTCGTTTCCCCCTGGAACCCATCTGGCCTCGGAGGTGGCCAGTCACAGACCAGG AATGCAATGTGGGTTTTTCCTGCTCCTGTTTTGCAGCAGCCGACATACGTCCAGGCCCTCTTTGACTTTG ATCCCCAGGAGGATGGAGAGCTGGGCTTCCGCCGGGGAGATTTTATCCATGTCATGGATAACTCAGACCC CAACTGGTGGAAAGGAGCTTGCCACGGGCAGACCGGCATGTTTCCCCGCAATTATGTCACCCCCGTGAAC CGGAACGTCTAAGAGTCAAGAAGCAATTATTTAAAGAAAGTGAAAAATGTAAAACACATACAAAAGAATT AAACCCACAAGCTGCCTCTGACAGCAGCCTGTGAGGGAGTGCAGAACACCTGGCCGGGTCACCCTGTGAC CCTCTCACTTTGGTTGGAACTTTAGGGGGTGGGAGGGGGCGTTGGATTTAAAAATGCCAAAACTTACCTA TAAATTAAGAAGAGTTTTTATTACAAATTTTCACTGCTGCTCCTCTTTCCCCTCCTTTGTCTTTTTTTTC ATCCTTTTTTCTCTTCTGTCCATCAGTGCATGACGTTTAAGGCCACGTATAGTCCTAGCTGACGCCAATA ATAAAAAACAAGAAACCAAGTGGGCTGGTATTCTCTCTATGCAAAATGTCTGTTTTAGTTGGAATGACTG AAAGAAGAACAGCTGTTCCTGTGTTCTTCGTATATACACACAAAAAGGAGCGGGCAGGGCCGCTCGATGC CTTTGCTGTTTAGCTTCCTCCAGAGGAGGGGACTTGTAGGAATCTGCCTTCCAGCCCAGACCCCCAGTGT ATTTTGTCCAAGTTCACAGTAGAGTAGGGTAGAAGGAAAGCATGTCTCTGCTTCCATGGCTTCCTGAGAA AGCCCACCTGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGA TCACAAGGTCAGGAGTTCGAGACCAACCTAGCCAACATGGTGAAACCCCGTCTCTACTAAAAATAAGAAA TTAGCCGGGTGTGGCACGCACCTGTAGTCCCAGCTACTTGGGAGCCTGAGGCAGGAGAATCGCTTGAACC TGGGAAGTGGAGGTTGAGTGAGCCGGGACCGTGCCATTGTACTCCAGCCTGGGTGACAGAGCGAGATTCC GTCTCAAAAAAAAAAAAAAAAAGCCCACCTGAAAGCCTGTCTCTTTCCACTTTGTTGGCCCTTCCAGTGG GATTATCGAGCATGTTGTTTTTTCATAGTGCCTTTTTCCTTATTTCAAGGGTTGCTTCTGAGTGGTGTTT TTTTTTTTTTTTTAATTTGTTTTGTTTTAAAATAAGTTAAAGGCAGTCCAGAGCTTTTCAGCCAATTTGT CTCCTACTCTGTGTAAATATTTTTCCCTCCGGGCAGGGGAGCCAGGGTAGAGCAAAGGAGACAAAGCAGG AGTGGAAGGTGAGGCGTTCTCCTGCTTGTACTAAGCCAGGAGGCTTTAAGCTCCAGCTTTAAGGGTTGTG AGCCCCTTGGGGGTTCAGGGAACTGCTTGCCCAGGGTGCAGTGTGAGTGTGATGGGCCACCGGGGCAAGA GGGAAGGTGACCGCCCAGCTCTCCCACATCCCACTGGATCTGGCTTACAGGGGGGTCGGAAGCCTGTCCT CACCGTCTCGGGGGTTGTGGCCCCCGCCCCCTCCCTATATGCACCCCTGGAACCAGCAAGTCCCAGACAA GGAGAGCGGAGGAGGAAGTCATGGGAACGCAGCCTCCAGTTGTAGCAGGTTTCACTATTCCTATGCTGGG GTACACAGTGAGAGTACTCACTTTTCACTTGTCTTGCTCTTAGATTGGGCCATGGCTTTCATCCTGTGTC CCCTGACCTGTCCAGGTGAGTGTGAGGGCAGCACTGGGAAGCTGGAGTGCTGCTTGTGCCTCCCTTCCCA GTGGGCTGTGTTGACTGCTGCTCCCCACCCCTACCGATGGTCCCAGGAAGCAGGGAGAGTTGGGGAAGGC AAGATTGGAAAGACAGGAAGACCAAGGCCTCGGCAGAACTCTCTGTCTTCTCTCCACTTCTGGTCCCCTG TGGTGATGTGCCTGTAATCTTTTTCTCCACCCAAACCCCTTCCCACGACAAAAACAAGACTGCCTCCCTC TCTTCCGGGAGCTGGTGACAGCCTTGGGCCTTTCAGTCCCAAAGCGGCCGATGGGAGTCTCCCTCCGACT CCAGATATGAACAGGGCCCAGGCCTGGAGCGTTTGCTGTGCCAGGAGGCGGCAGCTCTTCTGGGCAGAGC CTGTCCCCGCCTTCCCTCACTCTTCCTCATCCTGCTTCTCTTTTCCTCGCAGATGATAAAAGGAATCTGG CATTCTACACCTGGACCATTTGATTGTTTTATTTTGGAATTGGTGTATATCATGAAGCCTTGCTGAACTA AGTTTTGTGTGTATATATTTAAAAAAAAAATCAGTGTTTAAATAAAGACCTATGTACTTAATCCTTTAAC TCTGCGGATAGCATTTGGTAGGTAGTGATTAACTGTGAATAATAAATACACAATGAATTCTTCA    Download   Select all
Length	87634
OMIM ID	108355
HGNC ID	HGNC:4566
Unigene ID	Hs.444356
Ensembl ID	ENSG00000177885
PharmGKB ID	-

mRNA Information

mRNA ID	NM_203506.2
Exon	join(1..221,11945..12159,72913..73010,83883..84051, 85157..87634)
mRNA Sequence	>2885 AAGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGTATTGCTGCTTCGGCGACCGGGC GGCGGCAGCGGCGGCGGCGGCTGTGGCAGAGTCTGTGCCTGTGGCGGTGACGGCGGCGGGAGCA AGCGCTGCCCTCGCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGC CGGACGCTGAGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGT CCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCAGCAGGGAAGACTCCCTTCC CCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTT CAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGTTTTGAACGAA GAATGTGATCAGAACTGGTACAAGGCAGAGCTTAATGGAAAAGACGGCTTCATTCCCAAGAACT ACATAGAAATGAAACCACATCCGTTTGGAAACGATGTGCAGCACTTCAAGGTGCTCCGAGATGG AGCCGGGAAGTACTTCCTCTGGGTGGTGAAGTTCAATTCTTTGAATGAGCTGGTGGATTATCAC AGATCTACATCTGTCTCCAGAAACCAGCAGATATTCCTGCGGGACATAGAACAGGTGCCACAGC AGCCGACATACGTCCAGGCCCTCTTTGACTTTGATCCCCAGGAGGATGGAGAGCTGGGCTTCCG CCGGGGAGATTTTATCCATGTCATGGATAACTCAGACCCCAACTGGTGGAAAGGAGCTTGCCAC GGGCAGACCGGCATGTTTCCCCGCAATTATGTCACCCCCGTGAACCGGAACGTCTAAGAGTCAA GAAGCAATTATTTAAAGAAAGTGAAAAATGTAAAACACATACAAAAGAATTAAACCCACAAGCT GCCTCTGACAGCAGCCTGTGAGGGAGTGCAGAACACCTGGCCGGGTCACCCTGTGACCCTCTCA CTTTGGTTGGAACTTTAGGGGGTGGGAGGGGGCGTTGGATTTAAAAATGCCAAAACTTACCTAT AAATTAAGAAGAGTTTTTATTACAAATTTTCACTGCTGCTCCTCTTTCCCCTCCTTTGTCTTTT TTTTCATCCTTTTTTCTCTTCTGTCCATCAGTGCATGACGTTTAAGGCCACGTATAGTCCTAGC TGACGCCAATAATAAAAAACAAGAAACCAAGTGGGCTGGTATTCTCTCTATGCAAAATGTCTGT TTTAGTTGGAATGACTGAAAGAAGAACAGCTGTTCCTGTGTTCTTCGTATATACACACAAAAAG GAGCGGGCAGGGCCGCTCGATGCCTTTGCTGTTTAGCTTCCTCCAGAGGAGGGGACTTGTAGGA ATCTGCCTTCCAGCCCAGACCCCCAGTGTATTTTGTCCAAGTTCACAGTAGAGTAGGGTAGAAG GAAAGCATGTCTCTGCTTCCATGGCTTCCTGAGAAAGCCCACCTGGGCTGGGCGCGGTGGCTCA CGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACAAGGTCAGGAGTTCGAGAC CAACCTAGCCAACATGGTGAAACCCCGTCTCTACTAAAAATAAGAAATTAGCCGGGTGTGGCAC GCACCTGTAGTCCCAGCTACTTGGGAGCCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGA GGTTGAGTGAGCCGGGACCGTGCCATTGTACTCCAGCCTGGGTGACAGAGCGAGATTCCGTCTC AAAAAAAAAAAAAAAAAGCCCACCTGAAAGCCTGTCTCTTTCCACTTTGTTGGCCCTTCCAGTG GGATTATCGAGCATGTTGTTTTTTCATAGTGCCTTTTTCCTTATTTCAAGGGTTGCTTCTGAGT GGTGTTTTTTTTTTTTTTTTAATTTGTTTTGTTTTAAAATAAGTTAAAGGCAGTCCAGAGCTTT TCAGCCAATTTGTCTCCTACTCTGTGTAAATATTTTTCCCTCCGGGCAGGGGAGCCAGGGTAGA GCAAAGGAGACAAAGCAGGAGTGGAAGGTGAGGCGTTCTCCTGCTTGTACTAAGCCAGGAGGCT TTAAGCTCCAGCTTTAAGGGTTGTGAGCCCCTTGGGGGTTCAGGGAACTGCTTGCCCAGGGTGC AGTGTGAGTGTGATGGGCCACCGGGGCAAGAGGGAAGGTGACCGCCCAGCTCTCCCACATCCCA CTGGATCTGGCTTACAGGGGGGTCGGAAGCCTGTCCTCACCGTCTCGGGGGTTGTGGCCCCCGC CCCCTCCCTATATGCACCCCTGGAACCAGCAAGTCCCAGACAAGGAGAGCGGAGGAGGAAGTCA TGGGAACGCAGCCTCCAGTTGTAGCAGGTTTCACTATTCCTATGCTGGGGTACACAGTGAGAGT ACTCACTTTTCACTTGTCTTGCTCTTAGATTGGGCCATGGCTTTCATCCTGTGTCCCCTGACCT GTCCAGGTGAGTGTGAGGGCAGCACTGGGAAGCTGGAGTGCTGCTTGTGCCTCCCTTCCCAGTG GGCTGTGTTGACTGCTGCTCCCCACCCCTACCGATGGTCCCAGGAAGCAGGGAGAGTTGGGGAA GGCAAGATTGGAAAGACAGGAAGACCAAGGCCTCGGCAGAACTCTCTGTCTTCTCTCCACTTCT GGTCCCCTGTGGTGATGTGCCTGTAATCTTTTTCTCCACCCAAACCCCTTCCCACGACAAAAAC AAGACTGCCTCCCTCTCTTCCGGGAGCTGGTGACAGCCTTGGGCCTTTCAGTCCCAAAGCGGCC GATGGGAGTCTCCCTCCGACTCCAGATATGAACAGGGCCCAGGCCTGGAGCGTTTGCTGTGCCA GGAGGCGGCAGCTCTTCTGGGCAGAGCCTGTCCCCGCCTTCCCTCACTCTTCCTCATCCTGCTT CTCTTTTCCTCGCAGATGATAAAAGGAATCTGGCATTCTACACCTGGACCATTTGATTGTTTTA TTTTGGAATTGGTGTATATCATGAAGCCTTGCTGAACTAAGTTTTGTGTGTATATATTTAAAAA AAAAATCAGTGTTTAAATAAAGACCTATGTACTTAATCCTTTAACTCTGCGGATAGCATTTGGT AGGTAGTGATTAACTGTGAATAATAAATACACAATGAATTCTTCA    Download   Select all
Length	3181

CDS Information

   

Location	join(12082..12159,72913..73010,83883..84051,85157..85342)
CDS Sequence	>gi|156602649:359-889 Homo sapiens growth factor receptor-bound protein 2 (GRB2), transcript variant 2, mRNA ATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACGACGAGCTGAGCTTCAAAAGGGGGGACA TCCTCAAGGTTTTGAACGAAGAATGTGATCAGAACTGGTACAAGGCAGAGCTTAATGGAAAAGACGGCTT CATTCCCAAGAACTACATAGAAATGAAACCACATCCGTTTGGAAACGATGTGCAGCACTTCAAGGTGCTC CGAGATGGAGCCGGGAAGTACTTCCTCTGGGTGGTGAAGTTCAATTCTTTGAATGAGCTGGTGGATTATC ACAGATCTACATCTGTCTCCAGAAACCAGCAGATATTCCTGCGGGACATAGAACAGGTGCCACAGCAGCC GACATACGTCCAGGCCCTCTTTGACTTTGATCCCCAGGAGGATGGAGAGCTGGGCTTCCGCCGGGGAGAT TTTATCCATGTCATGGATAACTCAGACCCCAACTGGTGGAAAGGAGCTTGCCACGGGCAGACCGGCATGT TTCCCCGCAATTATGTCACCCCCGTGAACCGGAACGTCTAA    Download   Select all
CCDS ID	CCDS11722.1

Protein Information

      

Protein ID	NP_002077.1
Protein Name	Growth factor receptor-bound protein 2
Molecular Wt. (Da)	25075
Protein Sequence	>2885 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGK IPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSL NELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPN WWKGACHGQTGMFPRNYVTPVNRNV    Download   Select all
Length	217
Uniprot ID	P51587
Ensembl Protein ID	ENSP00000369497

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Phosphorylation	168
Y	Phosphorylation	160
Y	Phosphorylation	119
Y	Phosphorylation	209;-
T	Phosphorylation	211
T	Phosphorylation	170
K	Acetylation	6
K	Acetylation	6
K	Acetylation	50
K	Acetylation	50
K	Acetylation	109
K	Acetylation	68
K	Acetylation	38
K	Acetylation	38

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING)      View   

                                                                                                                                                                                                                                                                                                                                          

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
100	ADA	38	NP_000013.2	in vitro	9299436
351	APP	100	NP_000475.1	in vivo	12485888
867	CBL	1320	NP_005179.2	in vitro;in vivo	929   505   211   964   172   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000   000
919	CD247	1729	NP_932170.1	in vivo	7629168
933	CD22	114	NP_001762.2	in vitro;in vivo	11551923
971	CD72	118	NP_001773.1	in vitro	10820378
2099	ESR1	589	NP_000116.2	in vitro;in vivo	15173068
2534	FYN	655	NP_002028.1	yeast 2-hybrid	9344857
4869	NPM1	1246	NP_002511.1	in vitro	8633037
5058	PAK1	3995	AAC24716.1	in vitro;in vivo	12522133
5294	PIK3CG	3135	NP_002640.2	in vivo	10386953
6195	RPS6KA1	3402	NP_001006666.1	in vitro;in vivo	8630373
6855	SYP	2435	NP_003170.1	in vitro	8547634
7535	ZAP70	1495	NP_001070.2	in vivo	7629168
8660	IRS2	2878	NP_003740.2	in vivo	75   595   799   852   124
10298	PAK4	5675	NP_005875.1	in vitro	12529371
10603	SH2B2	16097	NP_066189.3	in vitro	92   337   739   856   458
10957	PNRC1	8412	NP_006804.1	in vitro;in vivo;yeast 2-hybrid	15122321
30011	SH3KBP1	2301	NP_114098.1	in vitro	11152963
53358	SHC3	12005	NP_058544.3	in vivo	12242309
54923	LIME1	7904	NP_060276.2	in vivo	16249387
58480	RHOU	6965	NP_067028.1	in vitro;in vivo	15556869

Pathway Information

                                                                                                                                                                                                                              

Pathway Name	Pathway ID
Acute myeloid leukemia	hsa05221
Alcoholism	hsa05034
B cell receptor signaling pathway	hsa04662
Chemokine signaling pathway	hsa04062
Choline metabolism in cancer	hsa05231
Chronic myeloid leukemia	hsa05220
Dorso-ventral axis formation	hsa04320
Endometrial cancer	hsa05213
ErbB signaling pathway	hsa04012
Estrogen signaling pathway	hsa04915
Fc epsilon RI signaling pathway	hsa04664
Focal adhesion	hsa04510
FoxO signaling pathway	hsa04068
Gap junction	hsa04540
Glioma	hsa05214
GnRH signaling pathway	hsa04912
Hepatitis B	hsa05161
Hepatitis C	hsa05160
Insulin signaling pathway	hsa04910
Jak-STAT signaling pathway	hsa04630
MAPK signaling pathway	hsa04010
MicroRNAs in cancer	hsa05206
Natural killer cell mediated cytotoxicity	hsa04650
Neurotrophin signaling pathway	hsa04722
Non-small cell lung cancer	hsa05223
Osteoclast differentiation	hsa04380
Pathways in cancer	hsa05200
Phospholipase D signaling pathway	hsa04072
PI3K-Akt signaling pathway	hsa04151
Prolactin signaling pathway	hsa04917
Prostate cancer	hsa05215
Proteoglycans in cancer	hsa05205
Ras signaling pathway	hsa04014
Renal cell carcinoma	hsa05211
Signaling pathways regulating pluripotency of stem cells	hsa04550
T cell receptor signaling pathway	hsa04660
Viral carcinogenesis	hsa05203

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd09941	56-150	SH2_Grb2_like
cl15255	56-150	SH2 superfamily
cd11946	Jan-56	SH3_GRB2_N
cl17036	Jan-56	SH3 superfamily
cd11949	160-212	SH3_GRB2_C
cl17036	160-212	SH3 superfamily
pfam00017	60-135	SH2
cd11804	Feb-53	SH3_GRB2_like_N
smart00252	58-139	SH2
cd11805	160-212	SH3_GRB2_like_C
cd00173	59-135	SH2
cd11948	Feb-55	SH3_GRAP_N
cd10354	59-135	SH2_Cterm_RasGAP
cd09935	58-136	SH2_ABL
cd11951	160-212	SH3_GRAP_C
cd09933	59-139	SH2_Src_family
cd10369	59-139	SH2_Src_Frk
cd11803	162-210	SH3_Endophilin_A
smart00326	157-211	SH3
cd11964	161-211	SH3_STAM1
cd11820	161-211	SH3_STAM
cd10408	58-145	SH2_Nck1
cd11947	Feb-55	SH3_GRAP2_N
cd09943	59-145	SH2_Nck_family
cd10347	60-135	SH2_Nterm_shark_like
cd11772	161-212	SH3_OSTF1
cd11963	161-211	SH3_STAM2
cd00174	160-209	SH3
cd11950	161-212	SH3_GRAP2_C
cd09940	58-143	SH2_Vav_family
smart00326	Mar-54	SH3
cd09932	59-136	SH2_C-SH2_PLC_gamma_like
cd10370	59-135	SH2_Src_Src42
cd09937	56-112	SH2_csk_like
cd11840	161-212	SH3_Intersectin_5
cd10362	56-139	SH2_Src_Lck
cd11769	Jan-54	SH3_CSK
cd10409	60-145	SH2_Nck2
cd10343	57-136	SH2_SHIP
cd11809	Feb-53	SH3_srGAP
cd10361	59-141	SH2_Fps_family
cd10358	59-146	SH2_PTK6_Brk
cd10402	59-134	SH2_C-SH2_Zap70
cd09931	60-138	SH2_C-SH2_SHP_like
cd11961	161-210	SH3_Abp1_fungi_C2
cd00174	Mar-52	SH3
cd10352	61-132	SH2_a2chimerin_b2chimerin
cd10360	59-135	SH2_Srm
pfam14604	163-211	SH3_9
cd10367	60-135	SH2_Src_Fgr
cd11766	161-212	SH3_Nck_2
cd10341	59-139	SH2_N-SH2_PLC_gamma_like
pfam00018	162-206	SH3_1
cd11840	Apr-55	SH3_Intersectin_5
pfam00018	Apr-49	SH3_1
cd11781	Feb-55	SH3_Sorbs_1
cd11772	May-54	SH3_OSTF1
cd10406	58-140	SH2_Vav2
cd09925	59-160	SH2_SHC
cd11803	May-54	SH3_Endophilin_A
cd10344	49-135	SH2_SLAP
cd10337	58-113	SH2_BCAR3
cd09942	59-141	SH2_nSH2_p85_like
pfam14604	May-54	SH3_9
cd11875	160-212	SH3_CD2AP-like_3
cd11830	Mar-54	SH3_VAV_2
cd10365	60-136	SH2_Src_Src
cd10418	60-135	SH2_Src_Fyn_isoform_a_like
cd11786	160-210	SH3_SH3RF_1
cd11996	161-210	SH3_Intersectin2_5
cd10340	60-135	SH2_N-SH2_SHP_like
pfam07653	160-210	SH3_2
cd11843	May-54	SH3_PACSIN
cd11995	161-210	SH3_Intersectin1_5
cd11828	160-210	SH3_ARHGEF9_like
cd11996	Feb-55	SH3_Intersectin2_5
cd11826	160-211	SH3_Abi
cd10368	60-139	SH2_Src_Fyn
cd09930	60-146	SH2_cSH2_p85_like
cd09944	59-136	SH2_Grb7_family
cd11845	Apr-52	SH3_Src_like
cd11875	Jul-54	SH3_CD2AP-like_3
cd11805	May-54	SH3_GRB2_like_C
cd11842	160-210	SH3_Ysc84p_like
cd10364	60-139	SH2_Src_Lyn
cd12142	160-212	SH3_D21-like
cd11781	163-210	SH3_Sorbs_1
cd11995	Feb-55	SH3_Intersectin1_5
cd11827	161-211	SH3_MyoIe_If_like
cd09938	59-135	SH2_N-SH2_Zap70_Syk_like
cd11841	161-211	SH3_SH3YL1_like
cd11956	Jan-53	SH3_srGAP4
cd11833	159-210	SH3_Stac_1
cd10363	60-139	SH2_Src_HCK
cd11782	Feb-54	SH3_Sorbs_2
cd11786	Mar-54	SH3_SH3RF_1
cd11819	163-211	SH3_Cortactin_like
cd10405	54-140	SH2_Vav1
cd11778	160-209	SH3_Bzz1_2
cd12055	162-210	SH3_CIN85_2
cd11976	Mar-54	SH3_VAV1_2
cd10371	60-135	SH2_Src_Blk
cd10407	58-140	SH2_Vav3
cd11818	Feb-52	SH3_Eve1_5
cd12061	161-213	SH3_betaPIX
cd12142	Jul-55	SH3_D21-like
cd11877	161-212	SH3_PIX
cd11824	Feb-54	SH3_PSTPIP1
cd10353	60-139	SH2_Nterm_RasGAP
cd11864	Feb-54	SH3_PEX13_eumet
cd11768	161-212	SH3_Tec_like
cd11766	Feb-54	SH3_Nck_2
cd11985	159-210	SH3_Stac2_C
cd11978	Mar-54	SH3_VAV3_2
cd09945	59-135	SH2_SHB_SHD_SHE_SHF_like
cd11823	163-210	SH3_Nostrin
cd12073	163-210	SH3_HS1
cd11820	May-53	SH3_STAM
cd11877	May-54	SH3_PIX
cd11775	Feb-54	SH3_Sla1p_3
cd09926	60-108	SH2_CRK_like
cd11874	162-211	SH3_CD2AP-like_2
cd11964	May-53	SH3_STAM1
cd11904	161-211	SH3_Nck1_3
cd11876	163-212	SH3_MLK
cd10399	60-139	SH2_Tec_Bmx
cd11866	May-53	SH3_SKAP1-like
cd11758	Apr-54	SH3_CRK_N
cd12057	Jul-55	SH3_CIN85_3
cd12059	163-212	SH3_MLK1-3
cd11959	163-210	SH3_Cortactin
cd11962	162-210	SH3_Abp1_fungi_C1
cd11817	Mar-52	SH3_Eve1_4
cd11882	161-212	SH3_GRAF-like
cd11920	Mar-54	SH3_Sorbs2_1
cd11845	159-209	SH3_Src_like
cd11870	161-212	SH3_p67phox-like_C
cd11862	160-206	SH3_MPP
cd10355	60-134	SH2_DAPP1_BAM32_like
cd11878	May-52	SH3_Bem1p_1
cd11919	Feb-55	SH3_Sorbs1_1
cd11758	160-211	SH3_CRK_N
cd10419	60-135	SH2_Src_Fyn_isoform_b_like
cd11882	Mar-54	SH3_GRAF-like
cd12060	161-210	SH3_alphaPIX
cd11826	Apr-54	SH3_Abi
cd11920	162-210	SH3_Sorbs2_1
cd12061	May-53	SH3_betaPIX
cd11873	Feb-54	SH3_CD2AP-like_1
cd11804	163-210	SH3_GRB2_like_N
cd11907	161-211	SH3_TXK
cd11806	Feb-53	SH3_PRMT2
cd11838	160-212	SH3_Intersectin_3
cd11824	162-211	SH3_PSTPIP1
cd11873	161-211	SH3_CD2AP-like_1
cd11842	Feb-54	SH3_Ysc84p_like
cd11778	Jan-52	SH3_Bzz1_2
cd11916	162-213	SH3_Sorbs1_3
cd12047	161-212	SH3_Noxa1_C
cd10392	60-137	SH2_SHF
cd11959	Mar-55	SH3_Cortactin
cd11771	160-211	SH3_Pex13p_fungal
cd09934	60-139	SH2_Tec_family
cd12059	May-55	SH3_MLK1-3
cd11796	163-210	SH3_DNMBP_N3
cd12058	163-212	SH3_MLK4
cd11823	May-54	SH3_Nostrin
cd11780	162-212	SH3_Sorbs_3
cd11763	160-212	SH3_SNX9_like
cd12046	160-212	SH3_p67phox_C
cd11971	161-213	SH3_Abi1
cd10366	60-135	SH2_Src_Yes
cd11923	Feb-55	SH3_Sorbs2_2
cd11843	161-210	SH3_PACSIN
cd11770	Apr-55	SH3_Nephrocystin
cd11817	160-209	SH3_Eve1_4
cd11951	May-53	SH3_GRAP_C
cd11876	May-53	SH3_MLK
cd11963	May-53	SH3_STAM2
cd12056	160-210	SH3_CD2AP_3
cd11812	161-210	SH3_AHI-1
cd11919	162-210	SH3_Sorbs1_1
cd11991	163-212	SH3_Intersectin1_3
pfam07653	Mar-54	SH3_2
cd10414	56-136	SH2_Grb14
cd11807	May-55	SH3_ASPP
cd11836	160-210	SH3_Intersectin_1
cd10397	60-142	SH2_Tec_Btk
cd11800	Apr-53	SH3_DNMBP_C2_like
cd11767	161-211	SH3_Nck_3
cd11998	May-54	SH3_PACSIN1-2
cd12054	162-210	SH3_CD2AP_2
cd12058	May-53	SH3_MLK4
cd11763	May-54	SH3_SNX9_like
cd11844	Mar-55	SH3_CAS
cd10411	53-137	SH2_SH2B2
cd11837	161-212	SH3_Intersectin_2
cd12005	Apr-55	SH3_Lck
cd11997	May-54	SH3_PACSIN3
cd12060	May-54	SH3_alphaPIX
cd12036	160-195	SH3_MPP5
cd11812	Apr-53	SH3_AHI-1
cd10350	59-141	SH2_SH2D4A
cd11928	May-55	SH3_SH3RF3_1
cd11955	Feb-53	SH3_srGAP1-3
cd11998	161-212	SH3_PACSIN1-2
cd11767	Feb-54	SH3_Nck_3
cd11791	161-211	SH3_UBASH3
cd11809	163-212	SH3_srGAP
cd11954	Mar-53	SH3_ASPP1
cd12052	Feb-53	SH3_CIN85_1
cd12003	162-210	SH3_EFS
cd11925	163-213	SH3_SH3RF3_3
cd11952	May-52	SH3_iASPP
cd12009	Apr-53	SH3_Blk
cd11783	160-212	SH3_SH3RF_3
cd11901	158-211	SH3_Nck1_2
cd12033	160-206	SH3_MPP7
cd11949	May-54	SH3_GRB2_C
cd11855	Mar-55	SH3_Sho1p
cd12007	159-214	SH3_Yes
cd12005	161-210	SH3_Lck
cd11950	Mar-54	SH3_GRAP2_C
cd10345	59-134	SH2_C-SH2_Zap70_Syk_like
cd12004	Apr-53	SH3_Lyn
cd11960	161-211	SH3_Abp1_eu
cd10390	58-137	SH2_SHD
cd09946	60-136	SH2_HSH2_like
cd11769	159-211	SH3_CSK
cd11807	161-209	SH3_ASPP
cd11905	Mar-56	SH3_Tec
cd11827	May-54	SH3_MyoIe_If_like
cd11974	160-210	SH3_ASEF2
cd11992	163-212	SH3_Intersectin2_3
cd12056	May-53	SH3_CD2AP_3
cd11956	163-211	SH3_srGAP4
cd11953	May-51	SH3_ASPP2
cd11884	160-212	SH3_MYO15
cd12053	Feb-54	SH3_CD2AP_1
cd11972	Feb-59	SH3_Abi2
cd11774	161-210	SH3_Sla1p_2
cd10346	54-137	SH2_SH2B_family
cd11903	161-210	SH3_Nck2_3
cd11904	May-53	SH3_Nck1_3
cd11762	160-206	SH3_FCHSD_2
cd11808	Apr-54	SH3_Alpha_Spectrin
cd12006	159-212	SH3_Fyn_Yrk
cd11837	Mar-55	SH3_Intersectin_2
cd12057	160-210	SH3_CIN85_3
cd11972	161-213	SH3_Abi2
cd11816	163-210	SH3_Eve1_3
cd10401	59-135	SH2_C-SH2_Syk_like
cd11762	May-54	SH3_FCHSD_2
cd11977	Mar-54	SH3_VAV2_2
cd11921	165-210	SH3_Vinexin_1
cd10348	60-135	SH2_Cterm_shark_like
cd09929	54-138	SH2_BLNK_SLP-76
cd11921	Mar-55	SH3_Vinexin_1
cd11819	Mar-55	SH3_Cortactin_like
cd10391	58-137	SH2_SHE
cd11990	162-211	SH3_Intersectin2_2
cd11927	Mar-55	SH3_SH3RF1_1
cd11970	161-210	SH3_PLCgamma1
cd12037	160-206	SH3_MPP2
cd12000	Jan-55	SH3_CASS4
cd11874	May-55	SH3_CD2AP-like_2
cd12007	Apr-53	SH3_Yes
cd11818	162-209	SH3_Eve1_5
cd12052	165-210	SH3_CIN85_1
cd11961	Mar-55	SH3_Abp1_fungi_C2
cd11883	160-209	SH3_Sdc25
cd11947	162-210	SH3_GRAP2_N
cd10412	58-136	SH2_SH2B3
cd10396	60-136	SH2_Tec_Itk
cd10356	60-132	SH2_ShkA_ShkC
cd11841	Feb-53	SH3_SH3YL1_like
cd12008	163-212	SH3_Src
cd10342	59-118	SH2_SAP1
cd11999	May-54	SH3_PACSIN_like
cd12003	Mar-57	SH3_EFS
cd11836	May-54	SH3_Intersectin_1
cd10413	56-136	SH2_Grb7
cd11815	164-210	SH3_Eve1_2
cd11813	162-210	SH3_SGSM3
cd10351	59-136	SH2_SH2D4B
cd11861	160-194	SH3_DLG-like
cd11948	163-210	SH3_GRAP_N
cd11918	162-213	SH3_Vinexin_3
cd11789	Apr-55	SH3_Nebulin_family_C
cd11973	160-210	SH3_ASEF
cd11782	163-210	SH3_Sorbs_2
cd12073	Mar-55	SH3_HS1
cd10398	60-136	SH2_Tec_Txk
cd11935	159-214	SH3_Nebulette_C
cd11928	160-210	SH3_SH3RF3_1
cd12080	160-206	SH3_MPP1
cd11821	161-209	SH3_ASAP
cd11765	Mar-53	SH3_Nck_1
cd11773	161-209	SH3_Sla1p_1
cd12006	Apr-53	SH3_Fyn_Yrk
cd11796	Mar-53	SH3_DNMBP_N3
cd10388	60-146	SH2_SOCS7
cd11976	162-210	SH3_VAV1_2
cd11929	Mar-55	SH3_SH3RF2_1
cd11952	161-209	SH3_iASPP
cd11901	Jan-53	SH3_Nck1_2
cd12064	Feb-54	SH3_GRAF
cd12012	13-54	SH3_RIM-BP_2
cd11825	161-210	SH3_PLCgamma
cd12066	Feb-54	SH3_GRAF3
cd10400	61-118	SH2_SAP1a
cd11927	162-210	SH3_SH3RF1_1
cd11902	158-210	SH3_Nck2_2
cd11816	Mar-53	SH3_Eve1_3
cd12054	Jul-54	SH3_CD2AP_2
cd11905	161-211	SH3_Tec
cd11894	May-54	SH3_FCHSD2_2
cd11764	160-213	SH3_Eps8
cd11986	160-210	SH3_Stac3_1
cd11933	May-54	SH3_Nebulin_C
cd11856	Apr-54	SH3_p47phox_like
cd11911	Mar-55	SH3_CIP4-like
cd12039	160-206	SH3_MPP3
cd12000	162-212	SH3_CASS4
cd11839	162-210	SH3_Intersectin_4
cd11971	Feb-58	SH3_Abi1
cd10415	60-136	SH2_Grb10
cd11771	May-54	SH3_Pex13p_fungal
cd11953	161-208	SH3_ASPP2
cd11761	Jul-54	SH3_FCHSD_1
cd11789	159-212	SH3_Nebulin_family_C
cd12045	Jul-53	SH3_SKAP2
cd12065	Feb-55	SH3_GRAF2
cd11999	161-210	SH3_PACSIN_like
cd11773	May-52	SH3_Sla1p_1
cd12013	Apr-54	SH3_RIM-BP_3
cd11774	Mar-53	SH3_Sla1p_2
cd11855	161-210	SH3_Sho1p
cd12055	May-54	SH3_CIN85_2
cd11894	160-206	SH3_FCHSD2_2
cd11849	161-211	SH3_SPIN90
cd11924	Feb-55	SH3_Vinexin_2
cd11830	163-210	SH3_VAV_2
cd10417	59-140	SH2_SH2D7
cd11764	Mar-55	SH3_Eps8
cd10349	59-135	SH2_SH2D2A_SH2D7
cd11922	Feb-55	SH3_Sorbs1_2
cd12030	160-195	SH3_DLG4
cd11810	Feb-52	SH3_RUSC1_like
cd12046	Apr-54	SH3_p67phox_C
cd11934	May-54	SH3_Lasp1_C
cd11878	161-209	SH3_Bem1p_1
cd11821	May-44	SH3_ASAP
cd11851	Apr-54	SH3_RIM-BP
cd11866	160-210	SH3_SKAP1-like
cd11850	Apr-53	SH3_Abl
cd11849	May-54	SH3_SPIN90
cd11902	Mar-53	SH3_Nck2_2
cd11906	Jan-53	SH3_BTK
cd12001	Mar-55	SH3_BCAR1
cd11929	162-210	SH3_SH3RF2_1
cd11887	158-212	SH3_Bbc1
cd12009	160-212	SH3_Blk
cd11903	Jul-53	SH3_Nck2_3
cd11906	161-211	SH3_BTK
cd12008	Apr-53	SH3_Src
cd12035	160-206	SH3_MPP1-like
cd11987	May-54	SH3_Intersectin1_1
cd11960	Mar-55	SH3_Abp1_eu
cd12002	162-210	SH3_NEDD9
cd11810	161-209	SH3_RUSC1_like
cd12034	160-209	SH3_MPP4
cd12044	Jul-53	SH3_SKAP1
cd11765	160-210	SH3_Nck_1
cd11926	163-212	SH3_SH3RF1_3
cd11997	161-210	SH3_PACSIN3
cd11933	161-213	SH3_Nebulin_C
cd12141	May-53	SH3_DNMBP_C2
cd11889	161-210	SH3_Cyk3p-like
cd11856	159-212	SH3_p47phox_like
cd11785	167-212	SH3_SH3RF_C
cd11847	Apr-53	SH3_Brk
cd11954	161-208	SH3_ASPP1
cd11912	Jul-55	SH3_Bzz1_1
cd12002	Mar-55	SH3_NEDD9
cd11770	160-210	SH3_Nephrocystin
cd11989	162-210	SH3_Intersectin1_2
cd11917	162-210	SH3_Sorbs2_3
cd11806	163-212	SH3_PRMT2
cd11908	159-210	SH3_ITK
cd11935	May-55	SH3_Nebulette_C
cd12012	163-210	SH3_RIM-BP_2
cd11934	162-210	SH3_Lasp1_C
cd12013	163-212	SH3_RIM-BP_3
cd11815	Mar-54	SH3_Eve1_2
cd11869	162-210	SH3_p40phox
cd11987	160-209	SH3_Intersectin1_1
cd11978	163-210	SH3_VAV3_2
cd11829	162-210	SH3_GAS7
cd11990	Nov-55	SH3_Intersectin2_2
cd11832	167-206	SH3_Shank
cd11907	Jan-53	SH3_TXK
cd10357	60-113	SH2_ShkD_ShkE
cd12031	160-217	SH3_DLG1
cd11858	May-54	SH3_Myosin-I_fungi
cd11768	Apr-54	SH3_Tec_like
cd12064	162-210	SH3_GRAF
cd11991	Feb-55	SH3_Intersectin1_3
cd12029	160-206	SH3_DLG3
cd12047	Apr-50	SH3_Noxa1_C
cd11895	161-206	SH3_FCHSD1_2
cd11887	Apr-54	SH3_Bbc1
cd11844	160-208	SH3_CAS
cd11797	160-209	SH3_DNMBP_N4
cd11833	Apr-53	SH3_Stac_1
cd11955	163-210	SH3_srGAP1-3
cd11879	Mar-55	SH3_Bem1p_2
cd11884	17-54	SH3_MYO15
cd11793	161-211	SH3_ephexin1_like
cd11862	17-49	SH3_MPP
cd11787	Mar-52	SH3_SH3RF_2
cd11790	161-213	SH3_Amphiphysin
cd09918	58-135	SH2_Nterm_SPT6_like
cd12024	Sep-53	SH3_NoxO1_2
cd12066	162-210	SH3_GRAF3
cd11787	163-209	SH3_SH3RF_2
cd11794	161-210	SH3_DNMBP_N1
cd12032	160-196	SH3_DLG2
cd11969	May-54	SH3_PLCgamma2
cd12038	160-210	SH3_MPP6
cd10410	58-136	SH2_SH2B1
cd12044	160-210	SH3_SKAP1
cd11865	163-210	SH3_Nbp2-like
cd12081	160-206	SH3_CASK
cd11793	Feb-54	SH3_ephexin1_like
cd11984	167-210	SH3_Shank3
cd11986	Apr-53	SH3_Stac3_1
cd11977	163-210	SH3_VAV2_2
cd11813	Mar-55	SH3_SGSM3
cd11988	162-210	SH3_Intersectin2_1
cd11870	Feb-54	SH3_p67phox-like_C
cd11783	Apr-53	SH3_SH3RF_3
cd12072	May-55	SH3_FNBP1L
cd11975	162-210	SH3_ARHGEF9
cd11828	Mar-53	SH3_ARHGEF9_like
cd11825	May-54	SH3_PLCgamma
cd11969	161-213	SH3_PLCgamma2
cd11941	Feb-53	SH3_ARHGEF37_C2
cd11865	Feb-55	SH3_Nbp2-like
cd09923	59-103	SH2_SOCS_family
cd11808	160-210	SH3_Alpha_Spectrin
cd11846	Apr-53	SH3_Srms
cd12011	Mar-53	SH3_SLAP2
cd12065	162-210	SH3_GRAF2
cd12068	160-212	SH3_MYO15B
cd11848	Mar-53	SH3_SLAP-like
cd11885	May-53	SH3_SH3TC
cd11898	Jul-55	SH3_SNX9
cd11958	Nov-52	SH3_RUSC1
cd10389	60-137	SH2_SHB
cd12017	Aug-54	SH3_Tks_3
cd11859	160-187	SH3_ZO
cd11989	Feb-55	SH3_Intersectin1_2
cd11790	May-54	SH3_Amphiphysin
cd11918	May-53	SH3_Vinexin_3
cd11791	Jul-54	SH3_UBASH3
cd11916	May-55	SH3_Sorbs1_3
cd09927	60-100	SH2_Tensin_like
cd11983	167-206	SH3_Shank2
cd11922	163-210	SH3_Sorbs1_2
cd11886	Apr-52	SH3_BOI
cd11957	161-211	SH3_RUSC2
cd11757	161-210	SH3_SH3BP4
cd11936	161-212	SH3_UBASH3B
cd12016	Apr-54	SH3_Tks_2
cd11780	May-54	SH3_Sorbs_3
cd11784	163-212	SH3_SH3RF2_3
cd12045	160-210	SH3_SKAP2
cd11924	163-210	SH3_Vinexin_2
cd11839	Feb-55	SH3_Intersectin_4
cd11923	163-210	SH3_Sorbs2_2
cd11800	160-212	SH3_DNMBP_C2_like
cd11871	Jul-54	SH3_p67phox_N
cd11895	May-54	SH3_FCHSD1_2
cd11900	Apr-56	SH3_Nck1_1
cd11864	162-211	SH3_PEX13_eumet
cd11899	Apr-56	SH3_Nck2_1
cd11871	164-213	SH3_p67phox_N
cd11970	May-54	SH3_PLCgamma1
cd11957	Nov-53	SH3_RUSC2
cd11777	Feb-53	SH3_CIP4_Bzz1_like
cd11795	166-210	SH3_DNMBP_N2
cd11965	Jul-55	SH3_ASAP1
cd11788	Oct-54	SH3_RasGAP
cd11937	161-209	SH3_UBASH3A
cd11811	Feb-48	SH3_CHK
cd12076	Apr-54	SH3_Tks4_2
cd11965	161-210	SH3_ASAP1
cd12001	162-208	SH3_BCAR1
cd12051	Mar-56	SH3_DOCK1_5_A
cd11860	160-192	SH3_DLG5
cd11975	Jan-55	SH3_ARHGEF9
cd12036	17-49	SH3_MPP5
cd11982	163-210	SH3_Shank1
cd10387	60-100	SH2_SOCS6
cd12033	17-52	SH3_MPP7
cd12021	Mar-54	SH3_p47phox_1
cd11858	159-212	SH3_Myosin-I_fungi
cd11854	Feb-49	SH3_Fus1p
cd12071	May-55	SH3_FBP17
cd11838	Apr-53	SH3_Intersectin_3
cd12053	165-213	SH3_CD2AP_1
cd11775	162-212	SH3_Sla1p_3
cd11908	Apr-56	SH3_ITK
cd11988	May-54	SH3_Intersectin2_1
cd11926	Apr-53	SH3_SH3RF1_3
cd11872	Mar-56	SH3_DOCK_AB
cd11940	161-212	SH3_ARHGEF5_19
cd12141	163-210	SH3_DNMBP_C2
cd12021	159-212	SH3_p47phox_1
cd11958	161-211	SH3_RUSC1
cd11974	Mar-55	SH3_ASEF2
cd11847	163-210	SH3_Brk
cd10404	59-134	SH2_STAP2
cd11869	Mar-55	SH3_p40phox
cd10416	60-114	SH2_SH2D2A
cd11850	163-212	SH3_Abl
cd11932	162-210	SH3_SH3RF2_2
cd12014	Apr-54	SH3_RIM-BP_1
cd12004	161-214	SH3_Lyn
cd12050	Apr-56	SH3_DOCK2_A
cd11883	Apr-52	SH3_Sdc25
cd09919	60-112	SH2_STAT_family
cd11857	Sep-51	SH3_DBS
cd12015	166-212	SH3_Tks_1
cd11985	Apr-54	SH3_Stac2_C
cd11899	161-210	SH3_Nck2_1
cd11962	Mar-55	SH3_Abp1_fungi_C1
cd11885	163-210	SH3_SH3TC
cd11757	Feb-54	SH3_SH3BP4
cd12081	May-49	SH3_CASK
cd11835	170-210	SH3_ARHGAP32_33
cd11761	158-211	SH3_FCHSD_1

Ontology Information

   

HPRD ID	2554
Molecular Class	Adapter molecule
Molecular Function	Transcription regulator activity (GO:0030528)
Biological Process	Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)

SNP Information

View SNP Geneview Report   

Drug Information

Uniprot ID	DrugBank ID	Name	Type
P62993	DB00061	Pegademase bovine	BiotechDrug

External Links

                                 

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO