Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| HIPK2 | 28996 | homeodomain interacting protein kinase 2 | 7 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25282590 | 2014 | Cell line : HCT 116, LoVo, HT 29,
SW62 Source : Chinese Academy of Science. General Surgery Department of our hospital. Sample Type : CRC tumor No. of Sample : 100 Stage : - | Immunohistochemistry,CCK-8 assay and flow cytometry | Down-regulation | - | HIPK2 protein modulates the phosphorylation status of p53, and levels of Bax and Bcl-2 in CRC. We also found that VB effectively activated the HIPK2-p53 signaling pathway, resulting in increased CRC cell apoptosis.100 human CRC tumor samples and 20 normal intestinal tissues, showed HIPK2 expression to inversely correlate with Dukes stage and depth of invasion in CRC |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| Chromosome | 7 |
| Location | 7q32-q34 |
| Start | 139415730 |
| End | 139477693 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 61964 |
| OMIM ID | 606868 |
| HGNC ID | HGNC:14402 |
| Unigene ID | Hs.731417 |
| Ensembl ID | ENSG00000064393 |
| PharmGKB ID | PA29291 |
Protein Information
| Protein ID | NP_001106710.1 |
|---|---|
| Protein Name | homeodomain interacting protein kinase 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 1198 |
| Uniprot ID | O95445 |
| Ensembl Protein ID | ENSP00000365081 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| K | Sumoylation | 1191 |
| Y | Phosphorylation | 361 |
| Y | Phosphorylation | 360 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 861 | RUNX1 | 1043 | NP_001745.2 | in vitro;in vivo | 16917507 |
| 1387 | CREBBP | 2534 | NP_004371.2 | in vivo | 11740489 |
| 1482 | NKX2-5 | 2787 | NP_004378.1 | in vitro;yeast 2-hybrid | 9748262 |
| 1616 | DAXX | 4424 | NP_001135442.1 | in vitro;in vivo | 14678985 |
| 3159 | HMGA1 | 2829 | NP_665906.1 | in vitro;in vivo;yeast 2-hybrid | 11593421 |
| 4086 | SMAD1 | 3356 | NP_005891.1 | in vitro;in vivo | 12874272 |
| 4087 | SMAD2 | 3221 | NP_005892.1 | in vitro;in vivo | 12874272 |
| 4193 | MDM2 | 1272 | NP_002383.2 | in vitro;in vivo | 16212962 |
| 4602 | MYB | 1810 | NP_001123645.1 | in vitro | 15082531 |
| 4824 | NKX3-1 | 3620 | NP_006158.2 | in vitro;in vivo | 10559189 |
| 5080 | PAX6 | 6167 | NP_001595.2 | in vitro;in vivo | 16407227 |
| 5727 | PTCH1 | 3200 | NP_000255.2 | in vitro;in vivo | 12874272 |
| 6497 | SKI | 1271 | NP_003027.1 | in vitro;in vivo | 12874272 |
| 7080 | NKX2-1 | 2798 | NP_001073136.1 | in vitro;yeast 2-hybrid | 11438542 |
| 7157 | TP53 | 1859 | NP_000537.3 | in vitro;in vivo | 11 925 430 117 801 200 000 000 000 000 000 |
| 7161 | TP73 | 3587 | NP_005418.1 | in vitro;in vivo;yeast 2-hybrid | 11925430 |
| 7919 | BAT1 | 805 | NP_004631.1 | yeast 2-hybrid | 14667819 |
| 8626 | TP63 | 4469 | NP_003713.3 | in vitro;yeast 2-hybrid | 11925430 |
| 8717 | TRADD | 4610 | NP_003780.1 | in vitro;yeast 2-hybrid | 11032752 |
| 8850 | KAT2B | 6780 | NP_003875.3 | in vitro;in vivo | 16917507 |
| 8945 | BTRC | 4596 | NP_378663.1 | in vivo | 18765672 |
| 10048 | RANBP9 | 4835 | NP_005484.2 | in vitro;in vivo;yeast 2-hybrid | 12220523 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14227 | 183-537 | STKc_HIPK2 |
| cl21453 | 183-537 | PKc_like superfamily |
| cd14211 | 199-527 | STKc_HIPK |
| cd14228 | 183-537 | STKc_HIPK1 |
| cd14229 | 198-527 | STKc_HIPK3 |
| cd14133 | 199-527 | PKc_DYRK_like |
| cd14212 | 199-527 | PKc_YAK1 |
| cd14210 | 182-527 | PKc_DYRK |
| cd14226 | 182-526 | PKc_DYRK1 |
| cd14134 | 196-526 | PKc_CLK |
| cd14135 | 199-527 | STKc_PRP4 |
| cd14225 | 175-527 | PKc_DYRK4 |
| cd05118 | 199-526 | STKc_CMGC |
| cd14224 | 175-527 | PKc_DYRK2_3 |
| cd07830 | 199-526 | STKc_MAK_like |
| cd07829 | 199-526 | STKc_CDK_like |
| cd14137 | 196-526 | STKc_GSK3 |
| cd07833 | 197-526 | STKc_CDKL |
| cd14213 | 199-526 | PKc_CLK1_4 |
| cd07834 | 199-526 | STKc_MAPK |
| cd14215 | 199-526 | PKc_CLK2 |
| cd14214 | 199-526 | PKc_CLK3 |
| cd14136 | 199-526 | STKc_SRPK |
| cd07831 | 199-526 | STKc_MOK |
| cd07851 | 197-531 | STKc_p38 |
| cd05117 | 199-526 | STKc_CAMK |
| cd00180 | 205-394 | PKc |
| cd07840 | 199-526 | STKc_CDK9_like |
| cd07852 | 199-531 | STKc_MAPK15-like |
| cd07846 | 197-526 | STKc_CDKL2_3 |
| cd07838 | 199-527 | STKc_CDK4_6_like |
| cd07848 | 197-424 | STKc_CDKL5 |
| cd14014 | 199-420 | STKc_PknB_like |
| cd07841 | 199-526 | STKc_CDK7 |
| cd07849 | 198-531 | STKc_ERK1_2_like |
| cd14132 | 199-526 | STKc_CK2_alpha |
| cd07832 | 199-528 | STKc_CCRK |
| cd05122 | 199-527 | PKc_STE |
| cd07877 | 199-531 | STKc_p38alpha |
| cd07860 | 199-526 | STKc_CDK2_3 |
| cd07878 | 199-531 | STKc_p38beta |
| cd07835 | 199-526 | STKc_CDK1_CdkB_like |
| cd07850 | 199-528 | STKc_JNK |
| cd07855 | 198-531 | STKc_ERK5 |
| cd07847 | 199-526 | STKc_CDKL1_4 |
| cd07843 | 193-526 | STKc_CDC2L1 |
| cd07837 | 199-526 | STKc_CdkB_plant |
| cd07863 | 199-526 | STKc_CDK4 |
| cd07836 | 199-526 | STKc_Pho85 |
| cd14002 | 199-527 | STKc_STK36 |
| cd05581 | 197-407 | STKc_PDK1 |
| cd07866 | 193-526 | STKc_BUR1 |
| cd07857 | 199-531 | STKc_MPK1 |
| cd14003 | 199-526 | STKc_AMPK-like |
| cd13999 | 205-420 | STKc_MAP3K-like |
| cd06606 | 203-420 | STKc_MAPKKK |
| cd07845 | 193-526 | STKc_CDK10 |
| cd07842 | 198-526 | STKc_CDK8_like |
| cd07861 | 199-526 | STKc_CDK1_euk |
| cd07858 | 205-531 | STKc_TEY_MAPK |
| cd07856 | 195-531 | STKc_Sty1_Hog1 |
| cd05123 | 205-410 | STKc_AGC |
| cd07880 | 199-531 | STKc_p38gamma |
| cd14098 | 199-526 | STKc_Rad53_Cds1 |
| cd14007 | 199-528 | STKc_Aurora |
| cd14006 | 205-415 | STKc_MLCK-like |
| cd07879 | 198-526 | STKc_p38delta |
| cd07865 | 193-526 | STKc_CDK9 |
| cd07876 | 275-529 | STKc_JNK2 |
| cd14009 | 205-405 | STKc_ATG1_ULK_like |
| cd14008 | 205-527 | STKc_LKB1_CaMKK |
| cd08215 | 199-394 | STKc_Nek |
| cd07854 | 199-540 | STKc_MAPK4_6 |
| cd14216 | 199-527 | STKc_SRPK1 |
| cd07859 | 199-526 | STKc_TDY_MAPK |
| cd14073 | 199-417 | STKc_NUAK |
| cd05579 | 207-399 | STKc_MAST_like |
| cd07875 | 199-529 | STKc_JNK1 |
| cd07864 | 199-527 | STKc_CDK12 |
| cd07871 | 198-526 | STKc_PCTAIRE3 |
| cd14105 | 199-424 | STKc_DAPK |
| cd07839 | 199-422 | STKc_CDK5 |
| cd07873 | 198-526 | STKc_PCTAIRE1 |
| cd05611 | 202-399 | STKc_Rim15_like |
| cd07862 | 199-422 | STKc_CDK6 |
| cd05580 | 197-399 | STKc_PKA_like |
| cd06627 | 198-401 | STKc_Cdc7_like |
| cd06623 | 200-531 | PKc_MAPKK_plant_like |
| cd06632 | 203-413 | STKc_MEKK1_plant |
| cd08217 | 199-394 | STKc_Nek2 |
| cd14080 | 199-390 | STKc_TSSK-like |
| cd07874 | 199-529 | STKc_JNK3 |
| cd06605 | 200-529 | PKc_MAPKK |
| cd14087 | 199-396 | STKc_PSKH1 |
| cd14077 | 199-397 | STKc_Kin1_2 |
| cd14086 | 197-527 | STKc_CaMKII |
| cd08529 | 199-394 | STKc_FA2-like |
| cd14120 | 205-391 | STKc_ULK1_2-like |
| cd13994 | 205-527 | STKc_HAL4_like |
| cd06614 | 199-528 | STKc_PAK |
| cd14121 | 203-405 | STKc_ULK3 |
| cd08530 | 199-394 | STKc_CNK2-like |
| cd14083 | 196-443 | STKc_CaMKI |
| cd13996 | 197-395 | STKc_EIF2AK |
| cd14084 | 195-527 | STKc_Chk2 |
| cd14113 | 200-397 | STKc_Trio_C |
| cd14218 | 199-527 | STKc_SRPK3 |
| cd14217 | 199-527 | STKc_SRPK2 |
| cd14196 | 199-414 | STKc_DAPK2 |
| cd14166 | 198-399 | STKc_CaMKI_gamma |
| cd14167 | 199-443 | STKc_CaMKI_alpha |
| cd06612 | 197-527 | STKc_MST1_2 |
| cd06917 | 199-484 | STKc_NAK1_like |
| cd14194 | 194-414 | STKc_DAPK1 |
| cd07872 | 198-422 | STKc_PCTAIRE2 |
| cd14010 | 199-399 | STKc_ULK4 |
| cd08528 | 198-394 | STKc_Nek10 |
| cd14164 | 199-397 | STKc_TSSK6-like |
| cd14089 | 205-525 | STKc_MAPKAPK |
| cd14099 | 198-399 | STKc_PLK |
| cd13993 | 199-412 | STKc_Pat1_like |
| cd14091 | 199-389 | STKc_RSK_C |
| cd14201 | 199-408 | STKc_ULK2 |
| cd05573 | 197-399 | STKc_ROCK_NDR_like |
| cd05570 | 205-412 | STKc_PKC |
| cd14169 | 199-443 | STKc_CaMKI_beta |
| cd14081 | 205-527 | STKc_BRSK1_2 |
| cd14195 | 199-414 | STKc_DAPK3 |
| cd06609 | 199-411 | STKc_MST3_like |
| cd14085 | 195-528 | STKc_CaMKIV |
| cd06608 | 196-399 | STKc_myosinIII_N_like |
| cd14019 | 197-526 | STKc_Cdc7 |
| cd07844 | 198-422 | STKc_PCTAIRE_like |
| cd14096 | 197-527 | STKc_RCK1-like |
| cd14093 | 199-399 | STKc_PhKG |
| cd14161 | 199-397 | STKc_NUAK2 |
| cd07870 | 198-422 | STKc_PFTAIRE2 |
| cd05572 | 205-411 | STKc_cGK |
| cd13985 | 198-391 | STKc_GAK_like |
| cd14168 | 199-427 | STKc_CaMKI_delta |
| cd14193 | 196-396 | STKc_MLCK4 |
| cd14092 | 203-391 | STKc_MSK_C |
| cd14209 | 198-399 | STKc_PKA |
| cd14046 | 197-423 | STKc_EIF2AK4_GCN2_rpt2 |
| cd07853 | 266-526 | STKc_NLK |
| cd14175 | 199-528 | STKc_RSK1_C |
| cd14016 | 199-351 | STKc_CK1 |
| cd14202 | 203-408 | STKc_ULK1 |
| cd14179 | 205-397 | STKc_MSK1_C |
| cd14182 | 199-526 | STKc_PhKG1 |
| cd06607 | 199-394 | STKc_TAO |
| cd14107 | 199-396 | STKc_obscurin_rpt1 |
| cd14114 | 199-408 | STKc_Twitchin_like |
| cd14131 | 199-402 | PKc_Mps1 |
| cd14183 | 194-528 | STKc_DCKL1 |
| cd14005 | 199-399 | STKc_PIM |
| cd14103 | 205-392 | STKc_MLCK |
| cd06626 | 204-399 | STKc_MEKK4 |
| cd14104 | 199-413 | STKc_Titin |
| cd05616 | 199-406 | STKc_cPKC_beta |
| cd13989 | 205-402 | STKc_IKK |
| cd14004 | 199-391 | STKc_PASK |
| cd14176 | 189-576 | STKc_RSK2_C |
| cd08219 | 199-394 | STKc_Nek3 |
| cd08220 | 199-394 | STKc_Nek8 |
| cd14095 | 199-525 | STKc_DCKL |
| cd14663 | 199-398 | STKc_SnRK3 |
| cd14185 | 199-409 | STKc_DCKL3 |
| cd14082 | 197-391 | STKc_PKD |
| cd07867 | 205-526 | STKc_CDC2L6 |
| cd05620 | 205-438 | STKc_nPKC_delta |
| cd06633 | 202-394 | STKc_TAO3 |
| cd05060 | 205-420 | PTKc_Syk_like |
| cd07869 | 197-422 | STKc_PFTAIRE1 |
| cd14048 | 197-455 | STKc_EIF2AK3_PERK |
| cd14047 | 195-395 | STKc_EIF2AK2_PKR |
| cd13982 | 205-526 | STKc_IRE1 |
| cd14191 | 196-414 | STKc_MLCK1 |
| cd05600 | 199-405 | STKc_Sid2p_like |
| cd14163 | 199-391 | STKc_TSSK3-like |
| cd14173 | 203-403 | STKc_Mnk2 |
| cd13997 | 199-411 | PKc_Wee1_like |
| cd14192 | 196-413 | STKc_MLCK3 |
| cd07868 | 205-526 | STKc_CDK8 |
| cd05587 | 202-406 | STKc_cPKC |
| cd06613 | 199-394 | STKc_MAP4K3_like |
| cd14171 | 194-399 | STKc_MAPKAPK5 |
| cd05615 | 199-406 | STKc_cPKC_alpha |
| cd05599 | 197-399 | STKc_NDR_like |
| cd14178 | 196-398 | STKc_RSK3_C |
| cd06625 | 205-395 | STKc_MEKK3_like |
| cd05574 | 199-397 | STKc_phototropin_like |
| cd06621 | 202-397 | PKc_Pek1_like |
| cd05591 | 205-408 | STKc_nPKC_epsilon |
| cd05038 | 205-457 | PTKc_Jak_rpt2 |
| cd14078 | 199-398 | STKc_MELK |
| cd14180 | 205-397 | STKc_MSK2_C |
| cd14117 | 197-413 | STKc_Aurora-B_like |
| cd14172 | 195-399 | STKc_MAPKAPK3 |
| cd05577 | 205-397 | STKc_GRK |
| cd05612 | 199-399 | STKc_PRKX_like |
| cd14177 | 196-429 | STKc_RSK4_C |
| cd14162 | 199-397 | STKc_TSSK4-like |
| cd06635 | 202-394 | STKc_TAO1 |
| cd13987 | 205-469 | STKc_SBK1 |
| cd13990 | 199-397 | STKc_TLK |
| cd06643 | 199-394 | STKc_SLK |
| cd14116 | 199-417 | STKc_Aurora-A |
| cd14165 | 205-391 | STKc_TSSK1_2-like |
| cd14038 | 205-402 | STKc_IKK_beta |
| cd14069 | 199-397 | STKc_Chk1 |
| cd06619 | 202-402 | PKc_MKK5 |
| cd06629 | 203-399 | STKc_Bck1_like |
| cd13979 | 202-407 | STKc_Mos |
| cd06636 | 199-399 | STKc_MAP4K4_6_N |
| cd14066 | 205-397 | STKc_IRAK |
| cd06637 | 199-399 | STKc_TNIK |
| cd05619 | 203-406 | STKc_nPKC_theta |
| cd14058 | 205-394 | STKc_TAK1 |
| cd14097 | 205-411 | STKc_STK33 |
| cd00192 | 205-405 | PTKc |
| cd14184 | 199-410 | STKc_DCKL2 |
| cd05601 | 197-397 | STKc_CRIK |
| cd06610 | 197-401 | STKc_OSR1_SPAK |
| cd06642 | 202-401 | STKc_STK25 |
| cd14186 | 199-399 | STKc_PLK4 |
| cd05578 | 199-453 | STKc_Yank1 |
| cd14090 | 203-408 | STKc_Mnk |
| cd14115 | 205-388 | STKc_Kalirin_C |
| cd05593 | 197-401 | STKc_PKB_gamma |
| cd13978 | 205-415 | STKc_RIP |
| cd08221 | 199-394 | STKc_Nek9 |
| cd05589 | 199-412 | STKc_PKN |
| cd14112 | 196-408 | STKc_Unc-89_rpt2 |
| cd05609 | 199-455 | STKc_MAST |
| cd14198 | 205-415 | STKc_DRAK2 |
| cd06620 | 200-397 | PKc_Byr1_like |
| cd14190 | 203-397 | STKc_MLCK2 |
| cd14108 | 196-396 | STKc_SPEG_rpt1 |
| cd08225 | 199-394 | STKc_Nek5 |
| cd06611 | 199-394 | STKc_SLK_like |
| cd14100 | 199-397 | STKc_PIM1 |
| cd05592 | 205-406 | STKc_nPKC_theta_like |
| cd05604 | 202-410 | STKc_SGK3 |
| cd06648 | 205-401 | STKc_PAK_II |
| cd06638 | 196-399 | STKc_myosinIIIA_N |
| cd06622 | 200-423 | PKc_PBS2_like |
| cd14205 | 202-428 | PTKc_Jak2_rpt2 |
| cd08224 | 199-423 | STKc_Nek6_7 |
| cd05608 | 205-394 | STKc_GRK1 |
| cd08218 | 199-394 | STKc_Nek1 |
| cd05632 | 197-406 | STKc_GRK5 |
| cd05627 | 197-412 | STKc_NDR2 |
| cd06634 | 202-394 | STKc_TAO2 |
| cd06659 | 205-532 | STKc_PAK6 |
| cd05571 | 205-401 | STKc_PKB |
| cd05607 | 203-397 | STKc_GRK7 |
| cd06644 | 199-394 | STKc_STK10 |
| cd14074 | 199-399 | STKc_SNRK |
| cd08223 | 199-394 | STKc_Nek4 |
| cd06628 | 205-421 | STKc_Byr2_like |
| cd05622 | 199-401 | STKc_ROCK1 |
| cd14174 | 203-403 | STKc_Mnk1 |
| cd05630 | 198-397 | STKc_GRK6 |
| cd14071 | 199-397 | STKc_SIK |
| cd14106 | 203-396 | STKc_DRAK |
| cd05605 | 205-397 | STKc_GRK4_like |
| cd14050 | 199-422 | PKc_Myt1 |
| cd14170 | 203-399 | STKc_MAPKAPK2 |
| cd14110 | 196-406 | STKc_obscurin_rpt2 |
| cd06657 | 205-401 | STKc_PAK4 |
| cd05586 | 205-401 | STKc_Sck1_like |
| cd06658 | 205-401 | STKc_PAK5 |
| cd05595 | 203-401 | STKc_PKB_beta |
| cd14037 | 200-394 | STKc_NAK_like |
| cd14039 | 205-398 | STKc_IKK_alpha |
| cd06631 | 203-405 | STKc_YSK4 |
| cd14181 | 199-399 | STKc_PhKG2 |
| cd06641 | 199-399 | STKc_MST3 |
| cd14197 | 205-415 | STKc_DRAK1 |
| cd05628 | 199-430 | STKc_NDR1 |
| cd14052 | 199-393 | PTKc_Wee1_fungi |
| cd14101 | 199-397 | STKc_PIM2 |
| cd05594 | 197-427 | STKc_PKB_alpha |
| cd06630 | 203-399 | STKc_MEKK1 |
| cd14075 | 205-388 | STKc_NIM1 |
| cd06640 | 202-399 | STKc_MST4 |
| cd05585 | 205-409 | STKc_YPK1_like |
| cd14017 | 198-397 | STKc_TTBK |
| cd05036 | 205-405 | PTKc_ALK_LTK |
| cd05631 | 198-397 | STKc_GRK4 |
| cd14065 | 205-394 | PKc_LIMK_like |
| cd06618 | 197-403 | PKc_MKK7 |
| cd05051 | 200-395 | PTKc_DDR |
| cd05617 | 199-397 | STKc_aPKC_zeta |
| cd05048 | 202-421 | PTKc_Ror |
| cd05603 | 205-399 | STKc_SGK2 |
| cd06639 | 190-399 | STKc_myosinIIIB_N |
| cd05602 | 199-410 | STKc_SGK1 |
| cd06653 | 203-428 | STKc_MEKK3_like_u1 |
| cd05621 | 199-401 | STKc_ROCK2 |
| cd05598 | 199-399 | STKc_LATS |
| cd14079 | 199-397 | STKc_AMPK_alpha |
| cd05148 | 199-421 | PTKc_Srm_Brk |
| cd14076 | 199-428 | STKc_Kin4 |
| cd06617 | 200-422 | PKc_MKK3_6 |
| cd05584 | 305-413 | STKc_p70S6K |
| cd14068 | 204-397 | STKc_LRRK2 |
| cd14060 | 206-395 | STKc_MLTK |
| cd14111 | 198-390 | STKc_SPEG_rpt2 |
| cd05618 | 199-397 | STKc_aPKC_iota |
| cd08222 | 199-394 | STKc_Nek11 |
| cd14000 | 205-397 | STKc_LRRK |
| cd06616 | 202-411 | PKc_MKK4 |
| cd05629 | 197-413 | STKc_NDR_like_fungal |
| cd05596 | 199-401 | STKc_ROCK |
| cd06652 | 203-399 | STKc_MEKK2 |
| cd05633 | 197-397 | STKc_GRK3 |
| cd14040 | 194-397 | STKc_TLK1 |
| cd08228 | 199-401 | STKc_Nek6 |
| cd06650 | 197-445 | PKc_MEK1 |
| cd05582 | 205-397 | STKc_RSK_N |
| cd05575 | 307-399 | STKc_SGK |
| cd14189 | 198-427 | STKc_PLK3 |
| cd05116 | 205-395 | PTKc_Syk |
| cd05092 | 205-395 | PTKc_TrkA |
| cd05059 | 202-415 | PTKc_Tec_like |
| cd05039 | 200-414 | PTKc_Csk_like |
| cd14072 | 199-397 | STKc_MARK |
| cd05590 | 205-408 | STKc_nPKC_eta |
| cd14094 | 199-565 | STKc_CASK |
| cd05032 | 205-413 | PTKc_InsR_like |
| cd14187 | 204-399 | STKc_PLK1 |
| cd05624 | 199-401 | STKc_MRCK_beta |
| cd14223 | 199-397 | STKc_GRK2 |
| cd14154 | 205-394 | STKc_LIMK |
| cd14020 | 259-400 | STKc_KIS |
| cd14665 | 199-402 | STKc_SnRK2-3 |
| cd14063 | 200-400 | PK_KSR |
| cd06647 | 199-420 | STKc_PAK_I |
| cd05080 | 205-395 | PTKc_Tyk2_rpt2 |
| cd05040 | 203-395 | PTKc_Ack_like |
| cd06654 | 199-420 | STKc_PAK1 |
| cd06624 | 205-399 | STKc_ASK |
| cd14070 | 198-388 | STKc_HUNK |
| cd06656 | 199-420 | STKc_PAK3 |
| cd05063 | 205-421 | PTKc_EphR_A2 |
| cd06615 | 199-529 | PKc_MEK |
| cd05115 | 205-422 | PTKc_Zap-70 |
| cd14013 | 301-527 | STKc_SNT7_plant |
| cd05614 | 199-397 | STKc_MSK2_N |
| cd14041 | 194-397 | STKc_TLK2 |
| cd05606 | 205-397 | STKc_beta_ARK |
| cd14119 | 205-388 | STKc_LKB1 |
| cd05034 | 205-415 | PTKc_Src_like |
| cd05049 | 205-415 | PTKc_Trk |
| cd05613 | 199-397 | STKc_MSK1_N |
| cd14049 | 197-423 | STKc_EIF2AK1_HRI |
| cd05033 | 201-393 | PTKc_EphR |
| cd14188 | 205-442 | STKc_PLK2 |
| cd14036 | 205-391 | STKc_GAK |
| cd05091 | 197-420 | PTKc_Ror2 |
| cd05070 | 197-420 | PTKc_Fyn |
| cd05057 | 200-411 | PTKc_EGFR_like |
| cd14102 | 199-397 | STKc_PIM3 |
| cd14203 | 205-421 | PTKc_Src_Fyn_like |
| cd05072 | 205-420 | PTKc_Lyn |
| cd14158 | 191-399 | STKc_IRAK4 |
| cd14059 | 205-397 | STKc_MAP3K12_13 |
| cd05597 | 199-401 | STKc_DMPK_like |
| cd05055 | 205-403 | PTKc_PDGFR |
| cd06646 | 199-394 | STKc_MAP4K5 |
| cd13988 | 205-388 | STKc_TBK1 |
| cd14147 | 203-403 | STKc_MLK3 |
| cd13986 | 282-390 | STKc_16 |
| cd14051 | 202-330 | PTKc_Wee1 |
| cd05626 | 205-426 | STKc_LATS2 |
| cd14062 | 205-410 | STKc_Raf |
| cd05623 | 199-401 | STKc_MRCK_alpha |
| cd06651 | 203-420 | STKc_MEKK3 |
| cd05588 | 205-397 | STKc_aPKC |
| cd13968 | 205-348 | PKc_like |
| cd05583 | 205-397 | STKc_MSK_N |
| cd05067 | 197-420 | PTKc_Lck_Blk |
| cd05097 | 203-395 | PTKc_DDR_like |
| cd05081 | 205-395 | PTKc_Jak3_rpt2 |
| cd05069 | 205-420 | PTKc_Yes |
| cd05065 | 203-421 | PTKc_EphR_B |
| cd14148 | 205-397 | STKc_MLK2 |
| cd05095 | 203-395 | PTKc_DDR2 |
| cd05083 | 203-405 | PTKc_Chk |
| cd14138 | 196-332 | PTKc_Wee1a |
| cd08229 | 205-394 | STKc_Nek7 |
| cd06645 | 199-394 | STKc_MAP4K3 |
| cd05050 | 205-413 | PTKc_Musk |
| cd06655 | 199-420 | STKc_PAK2 |
| cd05105 | 281-411 | PTKc_PDGFR_alpha |
| cd14012 | 267-395 | PK_eIF2AK_GCN2_rpt1 |
| cd05625 | 202-426 | STKc_LATS1 |
| cd05054 | 205-403 | PTKc_VEGFR |
| cd05071 | 205-403 | PTKc_Src |
| cd05046 | 205-395 | PTK_CCK4 |
| cd05090 | 202-420 | PTKc_Ror1 |
| cd05053 | 200-403 | PTKc_FGFR |
| cd05073 | 205-420 | PTKc_Hck |
| cd14118 | 205-389 | STKc_CAMKK |
| cd14109 | 203-397 | PK_Unc-89_rpt1 |
| cd06649 | 199-402 | PKc_MEK2 |
| cd14221 | 205-394 | STKc_LIMK1 |
| cd14155 | 205-394 | PKc_TESK |
| cd05112 | 205-395 | PTKc_Itk |
| cd14662 | 199-402 | STKc_SnRK2 |
| cd05084 | 203-421 | PTKc_Fes |
| cd14088 | 185-527 | STKc_CaMK_like |
| cd05079 | 205-395 | PTKc_Jak1_rpt2 |
| cd13995 | 203-422 | STKc_MAP3K8 |
| cd14027 | 205-412 | STKc_RIP1 |
| cd05066 | 205-421 | PTKc_EphR_A |
| cd05093 | 205-395 | PTKc_TrkB |
| cd05114 | 205-415 | PTKc_Tec_Rlk |
| cd14146 | 205-403 | STKc_MLK4 |
| cd05068 | 197-403 | PTKc_Frk_like |
| cd05099 | 205-403 | PTKc_FGFR4 |
| cd05052 | 205-403 | PTKc_Abl |
| cd14061 | 205-403 | STKc_MLK |
| cd14664 | 205-397 | STK_BAK1_like |
| cd14152 | 200-406 | STKc_KSR1 |
| cd13977 | 199-391 | STKc_PDIK1L |
| cd14067 | 289-397 | STKc_LRRK1 |
| cd05610 | 205-399 | STKc_MASTL |
| PHA02882 | 275-352 | PHA02882 |
| cd05096 | 203-396 | PTKc_DDR1 |
| cd05103 | 307-403 | PTKc_VEGFR2 |
| cd05576 | 307-400 | STKc_RPK118_like |
| cd14150 | 200-413 | STKc_A-Raf |
| cd05101 | 205-403 | PTKc_FGFR2 |
| cd14207 | 281-403 | PTKc_VEGFR1 |
| cd05113 | 202-395 | PTKc_Btk_Bmx |
| cd05082 | 200-402 | PTKc_Csk |
| cd05058 | 307-420 | PTKc_Met_Ron |
| cd05109 | 202-430 | PTKc_HER2 |
| cd14199 | 197-388 | STKc_CaMKK2 |
| cd14222 | 205-394 | STKc_LIMK2 |
| cd05044 | 204-413 | PTKc_c-ros |
| cd05056 | 203-420 | PTKc_FAK |
| cd05102 | 294-403 | PTKc_VEGFR3 |
| cd14145 | 203-397 | STKc_MLK1 |
| cd14159 | 205-397 | STKc_IRAK1 |
| cd05085 | 203-405 | PTKc_Fer |
| cd05107 | 307-402 | PTKc_PDGFR_beta |
| cd05111 | 202-411 | PTK_HER3 |
| cd13991 | 199-401 | STKc_NIK |
| cd14033 | 205-394 | STKc_WNK4 |
| cd05098 | 205-403 | PTKc_FGFR1 |
| cd14129 | 199-356 | STKc_TTBK2 |
| pfam06293 | 275-347 | Kdo |
| cd05100 | 205-403 | PTKc_FGFR3 |
| cd14130 | 199-350 | STKc_TTBK1 |
| cd05120 | 262-351 | APH_ChoK_like |
| cd14149 | 205-413 | STKc_C-Raf |
| cd05064 | 205-421 | PTKc_EphR_A10 |
| cd05094 | 205-395 | PTKc_TrkC |
| cd14031 | 205-423 | STKc_WNK3 |
| cd13983 | 203-391 | STKc_WNK |
| cd05041 | 203-405 | PTKc_Fes_like |
| cd14204 | 205-419 | PTKc_Mer |
| cd14200 | 199-388 | STKc_CaMKK1 |
| cd05061 | 201-394 | PTKc_InsR |
| cd14151 | 205-410 | STKc_B-Raf |
| cd14127 | 199-381 | STKc_CK1_fungal |
| cd05047 | 203-405 | PTKc_Tie |
| cd05104 | 307-403 | PTKc_Kit |
| cd05045 | 205-403 | PTKc_RET |
| cd05037 | 199-397 | PTK_Jak_rpt1 |
| cd14156 | 205-402 | PKc_LIMK_like_unk |
| cd14032 | 259-394 | STKc_WNK2_like |
| smart00220 | 199-527 | S_TKc |
| pfam00069 | 199-527 | Pkinase |
| PTZ00284 | 178-433 | PTZ00284 |
| COG0515 | 199-627 | SPS1 |
| PTZ00036 | 175-526 | PTZ00036 |
| PLN00009 | 199-526 | PLN00009 |
| PTZ00024 | 194-524 | PTZ00024 |
| pfam07714 | 202-421 | Pkinase_Tyr |
| smart00221 | 202-415 | STYKc |
| smart00219 | 202-420 | TyrKc |
| PTZ00263 | 199-399 | PTZ00263 |
| PHA03207 | 199-394 | PHA03207 |
| PTZ00426 | 199-399 | PTZ00426 |
| PHA03212 | 199-446 | PHA03212 |
| PHA03211 | 273-446 | PHA03211 |
| PHA03390 | 208-397 | pk1 |
| PTZ00266 | 194-410 | PTZ00266 |
| PHA03210 | 199-394 | PHA03210 |
| PTZ00267 | 223-506 | PTZ00267 |
| PHA03209 | 199-530 | PHA03209 |
| TIGR03903 | 221-405 | TOMM_kin_cyc |
| PLN00034 | 205-397 | PLN00034 |
| PTZ00283 | 307-394 | PTZ00283 |
| PLN03224 | 277-350 | PLN03224 |
| PLN03225 | 299-351 | PLN03225 |
Ontology Information
| HPRD ID | 12761 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.