CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
CD274	29126	CD274 molecule	9	B7-H, B7H1, PD-L1, PDL1, B7-H1

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
23785454	2013	Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 310 Stage : -	Tissue microarray and immunohistochemistry	Up-regulation	-	Univariate (P<0.001) and multivariate survival (P<0.001) analysis of 310 located CRC patients revealed that high level of PD-L1 expression was associated with increased risks of metastatic progression. PD-L1 can be used to identify CRC patients with high risk of metastasis and poor prognosis.

Gene Details

Chromosome 9 - NC_000009.12 (5450381..5470567)
View Larger Image

Gene Type	protein coding
Gene Family	CD molecules, "Immunoglobulin superfamily / V-set domain containing", "Immunoglobulin superfamily / C2-set domain containing", "Endogenous ligands"
Description	-
Chromosome	9
Location	9p24.1
Start	5450381
End	5470567
Strand	+
Gene Sequence	>gi\|568815589:5450381-5470567 Homo sapiens chromosome 9, GRCh38.p2 Primary Assembly CAACACTAGATACCTAAACTGAAAGCTTCCGCCGATTTCACCGAAGGTCAGGAAAGTCCAACGCCCGGCA AACTGGATTTGCTGCCTTGGGCAGAGGTGGGCGGGACCCCGCCTCCGGGCCTGGCGCAACGCTGAGCAGC TGGCGCGTCCCGCGCGGCCCCAGTTCTGCGCAGCTTCCCGAGGCTCCGCACCAGCCGCGCTTCTGTCCGC CTGCAGGTAGGGAGCGTTGTTCCTCCGCGGGTGCCCACGGCCCAGTATCTCTGGCTAGCTCGCTGGGCAC TTTAGGACGGAGGGTCTCTACACCCTTTCTTTGGGATGGAGAGAGGAGAAGGGAAAGGGAACGCGATGGT CTAGGGGGCAGTAGAGCCAATTACCTGTTGGGGTTAATAAGAACAGGCAATGCATCTGGCCTTCCTCCAG GCGCGATTCAGTTTTGCTCTAAAAATAATTTATACCTCTAAAAATAAATAAGATAGGTAGTATAGGATAG GTAGTCATTCTTATGCGACTGTGTGTTCAGAATATAGCTCTGATGCTAGGCTGGAGGTCTGGACACGGGT CCAAGTCCACCGCCAGCTGCTTGCTAGTAACATGACTTGTGTAAGTTATCCCAGCTGCAGCATCTAAGTA AGTCTCTTCCTGCGCTAAGCAGGTCCAGGATCCCTGAACGGAATTTATTTGCTCTGTCCATTCTGAGAAC CCAAAGGAGTCCTAAAAGAGGAATGGAGGAGCCTAAGAATAAAAATAGTATAATAAAACATTTCTTAGAC ACATTGACCTTGGCCTATGTCAAAGTTCAGTCTGGGTTTGTCTTATAACACAAGGAGTAAAAGTACCATT GTTCTACCTCTTTTTTTAATACTTGAAAAAAATTTACTGTGGATGCTTTTCTATGAATTAAATAACCTTC TAAAAAATGTTTTCATTGCTGCATTCGATTAGATTGGGTAACTAAATGAAATTAATTCCTCACTGTTGGG TATAAAGGTTATTTACAGTGGTTCTGTCTTAGCCATTCACTGAACTCATTGCATATATATCTCTGGAATA TTGCTGATTGTTTCCTTCAAGTAAACTTAGAAGTGTAACTACTTAGTCAAAGAGCCTGAATATTTTAAAG GCCTTTTGAAGAAAACTGAAAATGCTTTCCAGAAAGGATGTATCAGTTGACAATGACAGTCGTCAACAGT ATTTAAGGAGAACTATGATACTCTGAAGAAAAACTTAGCCTTTCTCAGTAAAAGTAGGTAGGCAGAGGCC ACATGACAGCAGTTAGAGTGTGGTCTTCAAGGAAGTCACAGAAATACTGTGGGGAATTGAAACCCCATGT GGAAAATGTACAAGAGTGTCTCAGTGTGACTGAGAAGGAGGTTGGGCATGGGGTTTCATGGAGTTTAATA AAGTTTGGTCACTTAGTAGAGGTTTAATAAATCAACTGTCTTAATCTTTGATCCTACTTAAGAATTTTTT TTTTGTTTTTGTAGAGATGGGGCTCTTGTTATGTTGCCCAGGCTGTTCTCGAACTCCTAGCCTCAGGCGA TCCTCCCTCCTCAGGCTCCAGAAGTCCTGGGATTACTGGCGGGAGCCACCATGCAGGCCTCTTGCTCCTA CTTTTGAGAAAGGAAGTTTAACCGGTTTTTTTTGTCTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTC TGTTGCCCATGCTGGAGTGCAGTGGTGCAATCTCAGCTCACTGCCTCCCGGGTTCAAGTGATTCTCCTGC CTCAGCCTCCCGAGTAGCTGGGACTACAGGCACCTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTA GAAATGGGGTTTCACCATATTGGCCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCCGCCTGCCTCGG CCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCTCCTGGCTGCTTAACTTTTTCTCTATCTCATC CTCCTACCCATCCTACCCTTGGAAGATAGAGAAGTAGTATTAGTTCCATAGTGTTATACTGGGCTTCCCC CAGGGACAAACCCACTTCCCCAACCTGAATGAGCCATCACTTCTTCCCCAGTTTACATTTCATTGCTCTT TAAATGTCTCCATTCGGATATGGGAATTCACATATGGTCATAATTCTTACCTGAAGAAGATGTCAGTCTT CTTCTCTTAGACCAACTGCCCTGATATGAGGTTTAGAGGTTAAAGAACATGTGTGTATTTACATGATCTT TGTATTCTGCCTTTTCGTCCCTCACTAATGACAGCTGCACCCCAAGGAAATGGAGCTGTGGAAGAGAGGG TTTGATAAGAAATTAAGTAAATATTGGATCTAATCCATCACCCTCCAGGAAGCCTTTATTACTCCTAAAA ATTTCAACCAAATTCATTAAAGGACAAGAACTCCACCAGAGTAGGCCATAAACATTGGCAAAATTAGTTG TAATCCATGACTAGATTTAATGTCCCTTTGTTTTATTCCCATATGGTTATAATGCTTTGCTTGGCATTAG GGGTATTTTAAGTTTTCTTCTGCCTAGTAAGTGAATTTGTGTTTATAATACAATAATCATAAAATATCAC ATTAATATTTTATAACTGTACAGTTATAAAATATTTTATAAGTAATATTTATATTTTATAAGTAATATTT TATAACTGTACAGTTAACTCTGGCCCAAGGAAAAGATAGTCTGATAGATGCTGCAGCCCCATTTTAGCAA ATGTGACCTCACAGGCCTGAATGCCATCGCTATTCCACATCTACAGGATAGACGGAAAGGAAAGAAATAA AAAAATAGGTACCTAACACTGGCAAGAGGATGATGACTCATGTTATTTCACTTAACCTTTTTATCTTTTA ACATGAAGGACTCATACAGGTTGATAAGAAACCAGTGACATAAACAGACCAAAAAATGATCAGATCTTTC AAATTAGCAAAAAAATAATATTTTTTAAACAATGGGTGAAAATACAGTGTAACAGTACCAATTATCAACA TGTGTTGAGAACCAGAAAAATGTTCTTTTTCTTTGATCAGCAACACTATTTGGGAAAATCTATCCTCAGG GCCTAGCCTGGGGCCCTGGCACACAGTAGGCACTCAACGAATATTTGCTGAACACACAAATACTTATGAT ATTTTAAAAAATTGGCAACAATCTGATACCTAACAATAGAGGGATTAAATATTATGGAACTGTTAAATAA GATGCTTATGAATACCATGCAGTAAGATGGGCAATATTTATGCCATAAGCTTTAATGAAACAAATGGGTA TTAAATGTATGATAAGGTTATAAATTACTTTTTAAAAGATTACAGGGAAAAAAATTGAAAGATATACACT GAAATGTTTTTTGCTCACAGTGGTGACAAGGTTTCTCAGCACTGGCACTGTTGACGTTTTAGGCTGTATG TCTTTGCTGTGGGAGGCTGGCCTGTGCACTGCAGGGTGTTTGGCAGCACTCTTGGCCTCTGCCCCTAGAT AGCAATAGCAGTCCTCCCTCAACCAGCCCAATTTTGACAACCAAAAATGTTTCCAGGCATCACCAGATGC TCCCTGGGTGAGAGTGATGAAATAGTAGGGGATTTTCCCCTTCTTTTCTTATTTTCTGTAATTCCATTAT ATTACTTTAATAATAAAGAAAAAAACATAAAAAATAAACGAATGTTATTATTCTACGTCAGTTTGGATGT TTGGACTCCATTTTGGGGTTCTTTCCATTATATCACTTGGTCTGCTAAACATTCTACGGTTTGGTAAGGT GAAGTGATTCATGAAATTTTGGTTTTATTTTTTTCCTGATACTAAAAATAAAACATTCTTTCACTTGGAA ATTTGGACACAGAACACCAAAAAAAATCCATAATCTCATCTCTCTTTTTCTGTCTTTTCCTTCCTTTTTT CCCTTTAAAAACAATAAAGAGTGAAACCTACCTGTTCTCCCTCTAATTTAATTCCTAAATATAATCACTG TCAATATCTTGGACATTTCCTGTGTCTAAACACACACACACACTTTTTTTTTTCAGCAAAAGTGGATTTC TGCTACATGTAGTGTTCTGCAACTTACTTTCTATGTGTTTACAAAATCAGTACATGTACATATGCTGAAT TCAGTCCTTAATGGTATTATATTTTGTGAATATACCAAAATTTGTTTAACCACTTAGACAATCTAGGATA TTCTCAGTTTGCTGTTATGAGCAATGCTCTTCCTTTACATATACAGACATATATATATATATGTGTGTGT GTGTGTTTTTGTTTTAGTAGGATAGATTTCTAGGAGAGGGTGAAAGGTCTTATGACATCCGCATTTACGA TTGTAATAGGAAGTATCAAAGTGCCCCCTAAAGAAAAAAATCCTCCCATTAGTGGGTAAGAAAGCCTATT TGTTCATATCTTCACAAACACTAAATATTAGAAATATTTACAATTGTGGTCAAGCTCATAAGTGAAAATG GTATTTCATATCTTATATTTTTTATTGTGAGATTGAACATCTTTCATATGTTTACATGTCACCTGTATTT CTTATTCTCTGAACTATATGTTATGACCTTTCACTTTTTTTCCTCATGGGTTATGTGTAGTTTGTATAGT TGTCTTATTGATTGTTAGGAGCTATTTATATATTAGGAACATTAATCTCCTGTCTTATATATACGTGGCA TCGATTAGTTGATCATTTGTGAGTTCATGTCTGTATACAAAGATTGGAGAGGCACTAAGAGGGAAAACTT ACCTCTTTCTTATCAAAGTTTGTAAATATATGTATAACAGAAGAGGGAGAAAATATTAATAAATGCACAG ATTGGCTGAAATAGAGTATAAATCTTTTACTCCCCTACTTCAACATAAACTGCAAAAGGAGAGTGACTTT TCTTTCACTCTGACTTCCGTATTCCTCATGCTTAAAATAGTGCCTAGCACAGAAGAGGTGCTCAATCAGT GTTTGCTAAACGAAATAATTAGTCACATTTCAAGCAGGATGACTAAATGAAGAATAGAATCTAGGCAGAT ACTCTGGAAGAGTGGCTGTGAGTCATTCATATCTTAGTATGAATTAGTCAAATCCAACTCTCTCCCCTTC CCACTCCCCACTGTTAGTAGAAGAATCTGTTTATTGAGAGAATAGATTTATAATTTAGAATAAGTGAGAG GGGCAGAAGAGGAGATTTTGAAGGATGGCACCTGAAGGAGGACTAGCATGGCTGAGACAGTGAAGTGGAA GCCTTGAATAGCTAAAGGGTAAGATGAAAGTATTTAGCTGTAGGGGGAAAAAGCATTGACAGGTTGGAAA AGTAAAAGTCAGATTCTCCTTGCTCTGAAATTTTGTACAGGGCAGGTTCTACTAGGTATGTTACAATGCA GAAAAAACATGAAATAATTGAGAGGAATTTGGTGCAATATTATCTTCTTGGCTTCTTTTGAGTGGGCAGA TTTTTTTCACGGCCTGTAACTATAATAAATTTGAAACTTCTCATCTTTTAGTAACTTTTTTCACTTAAGT TTATGTGGCTGTGGGCAATGGAATGAAGATATTGAACTTCCAATTCCCTGTTGGGTTTCCACAATTACAA GTCAATCATGACTGGTTATTAGAAGACTATTTCAGTTAGAACCACCAAGTCCCATATTGTCATATTGTAT GTTTAATTATTAAGTGAAGCAGTCTTCTTTTCGTGTTTTCCATAATTAGGGCATTCCAGAAAGATGAGGA TATTTGCTGTCTTTATATTCATGACCTACTGGCATTTGCTGAACGGTAAGACACCAAATCCTTCCATTAG GTTCTATATTTTAAATATTTTAACCATGAGTTTAAAACTAAAATGATCATTTAAAATGCATGCAATTTTC TTATAGAGAGAACATTCTATTCTTTCTTCTACTTTACACAATGGCAAAGTCTTCTTTCTACTTTACGCAA TGATAAAGTTACCTGTGTCATTTTGTAAAAATATAGAGAATATAGACAAATTGAAAGACACAAAATAATC TATTACCCATTTCCCAGGGTTAACTACTGAAAATATCTGGGGAAATGGCCTGTATGTATACATTTATTTG TTTGCTTTCAACAAGGCCAAGATCCTTTGATCTTTCAGTCTTGGTTGCTCTGTGACATGCCTTTCCTGAT GAGGATACTTTAAGGAAGAATTGTAAGATACATGGAAAATGTCAGGCTAACACAGTACTGGCATCACCCT GTGCTCTTTCCTGAACTCCATACCAATGTACTTCTTGCCAGAAAACTGATCAAAAGTTTAGGGAAGTAAA AAGAGATGACTGTTAGAATCTACCATTCCCTCTATGTAGGAAGCAAATAGGTGTCCTGTCAAAGGACATT CTGGGGATGTCTACATGAAACCAAGTCTCCCTGGTTGTAAGGACTCCATCTCCATATAATATTTATACAG TAATATATGTTTATAAATTGTGGGGGCAACTTGTTTAGCTAATTTTATTATTCTGCTATTGGGACACTGT GTCTCAGCATGAGATATAGTGTCCCAAAACATATTTCAAGCCCATTGGATAAAATATGTGTTTAGCAAGT TCTTAAATATAATGATAACATAACCGACCAGATAAAGTGATTTATAAACGCTGTGCCAATTTTGTAAATG TTTCGAGGAATTTTCCCTTTTCTGAAGATTGTCCTTCTTTCTTTTTAGCATTTACTGTCACGGTTCCCAA GGACCTATATGTGGTAGAGTATGGTAGCAATATGACAATTGAATGCAAATTCCCAGTAGAAAAACAATTA GACCTGGCTGCACTAATTGTCTATTGGGAAATGGAGGATAAGAACATTATTCAATTTGTGCATGGAGAGG AAGACCTGAAGGTTCAGCATAGTAGCTACAGACAGAGGGCCCGGCTGTTGAAGGACCAGCTCTCCCTGGG AAATGCTGCACTTCAGATCACAGATGTGAAATTGCAGGATGCAGGGGTGTACCGCTGCATGATCAGCTAT GGTGGTGCCGACTACAAGCGAATTACTGTGAAAGTCAATGGTAAGAATTATTATAGATGAGAGGCCTGAT CTTTATTGAAAACATATTCCAAGTGTTGAAGACTTTTCATTCTTGTAAGTCCATACTTATTTTCAAACAG AACAGCATAGTCTGTTCATTCATTCATTCAATTCATGAATTCATTCACATAATTATCCAATTTCTTGAGC ACCTATTTGATAGTCACTGGAAATCCAGAGACAAACAACACAGAGCCATGTTCTACAGTATGTACAGTTT TCCAAAAAGAATTTCTAGTCTTTACTTTTTTATTACAAATGGAATACGTATACTTGCAAATAATTCAGAT ACTGTGGAAGAGATCAAATGAATTGCAAAAGTGTCCCTCCTCCCTTCACCACTATCTCCCATGGCATGCA GAGAGAGTAACCATTATTTGTGTGTCCCTCCAGAAATTTTTTTATTCAACTACTATTTTTTTATTTTATT AGGTCCGTCAGTTTTCCTTTTTTGAGCCTCTCTATATCAAATGCAAATAAATATATTCAGAACAAACCCC ACTGTAAGGTTCACATTAAAAAAGACTTGAAGTCACCCTATGAAGACAAAAAATAATCACATTAAGTGTG AAAGAACCTATTCTTCCAGTACAGGATAAGCCATACTTACTGGGCATATATTCATCTTGAAAATCTATAC TGATGTTGTCTTGGGGAATTGAAAAGGAACTAGGAGTGTTAGTTCCTCGGTATTGACCCACAGTTATGTT ATCAGGTCACTTGAGTTCAAAGTTTTGTGTTGGCACTAGCTAAGTAAAGGAAAACACCTCTGCTTTCATT GTTGAGTTTCACAGAATTGAGAGCTGAAAGGATCCCAGGCAGGAGCAGCTAATCCAAACTCCCACAAAGA ACAAAAATCCCCCAGAGGATCTTCTGTTCTTATATTTCCTGCAATGGCGTCCCTGTCATATCCCACAATG GCCTCCCTGCCATTTGGATATCCCTTCCATATCCTGTTGAAATTACTCCCTAATAGTAAGCTGAAATCTG CCCCTCTAGTTGTAGTCTTGGGATTATTTCATTTACATGATGACCTTTTAATATTTGACTAGAATTAAAT CATCTCCCCTTGGTCTTTCCATTCCTGGGCTAACTACCATCAATCTGAGGGCTAACAATACAAGTAGAAA AAGTATACATTTGTCACTGATCACTGATCAATTATTAATCAATGATCACTGATAACTATAAACTCAAAAA CAAAATCATGTGGGGATTAAGAGAAATGTATCAGTTTTATGTTGTATTTCTGGTCCCTGATACTGGCTCA GGTAATGCCACTATTGTCAAGAAGATACCACTTGTAAAGTAGATTTAATTTTCATTATATTTTACCATAT GCTTCTCCATTCATGACATCTCTTGAGATGTTGTGGTTTATACTTTCAGTTTTTCTCCAGTCCATCCGCA AATATCAGGCATCTACTGTGTTCCAAGATATTAAAGAAATCATCATGACTTAGCCTCATCAACAGCATTG CTAGATCTGGGATGGAAAGGAAGAGTATAATCCTGGCAGTCAGGAAGAAGGCAGCATAAAGTATAAGTTT CTGCTTCCAAAAAAGGTCTCTCATCAGCCTGTAGGGAGTGTGTAGGGAAGGGACAGCTGTCCTTGTAGTA GGGAAGGGTTTTATTCAGGTCGTCTGGGCTCCATAATATCCCTTGTGTATCTGCAGTCTCCTTTGCCATG GATCAACACAATAGGAAATCTTCCGGCACTGATGGTTTTTCCAAGGGGGAGTTCTTCCTGGAGCAAAGCA AATGACCAACCAGGTTTGAGGACCTGATTTGTTTGACAATTCCATTTTGTATTGTAAATTACTTAATTGG CATTCTACTCCCAATCCATCTTGTCATTTGCATACAGTGGTTTTGGGATTGAGTTCAGCTATACCAAAAG TCTGAACCTTCTGCACTTAGAACAAGGCAACCACCAAGCTTCACTTGCACTGAGGCCGTGTCTCCAATGG AAATGAGGCAGCTGGCTTGCAGGAGCTTCCCAACTCAGGGAAGTAGAACTCCTGAGTCACCTCCATATGC AAATGATTTCACAGTAATGCTGTTGAACTTCACTTCCCATCACAGCAAATGTGTGGTAACATAGCTTCCC CACAGGAGTTTACTCACCATGGTATTTTAAAGGTGAAACATTTCAAAACTGAAATTTGAAAGAATTTAGT TTTGGATTCACTCAATTATCACTATCACTTCGGGTGTTATTGCACCTTTCTTGTTTGTGAGTTTAAATGC CAGACTCTCAGGCCACTAACTTTCAATTAAAAGTGTTTTTCTTTAATCGCTGAACCTAACAGCAGGGAAA ACGAAATGTTCATTCAGACTTTCAGAACCTTCAATGAGATTAGGCAGCTGAAAGATCAAAGTGTTGCATA GTTGTCCCGATAAAGCTATTTGGATCATATGGACCAAATCGACTGCTGTCATTCCCCACCAACCCCATCT CTCCCCAAAATTCCCAGCCCTGTTTAAGTGTTCTCTGTAGCATTTATCTCTATCTAGTATATTGTGTAGC ATATCATATCATACTTTTCTGTTTTGTTTATTGTCTCTCTCCTCCTAGAATATAAACTCCACAAGCACAA AGATTTGGGCCTGTTTTATAATATTGTTGCATCCCCAGGGCCTGATATACAGCAGAGTGGTGGTACGAAA AGAGCACACAAAAAAATATTTGTTGAGTCAATGAATGAATGATTTCCTCAAATAGGATTAGCCTAAAATT TTGGAAACATGAACAGATTTGGATATGTGAAAATTTATTTCCAGACTGTTCATCAGGAACTGTTAGCAGC TTCTAAAGGGTACACTGGAGCAGCAGTAGTAAAAGGAGGAAGAGGAGCAGCTCTGCTACTGCTACTATCG AGTACTACTACAATTAGCACTTGCTTATTCTGTGTGTTAGGCCCTGTACTGAACACTCTGTCTAAATTAG TTCATTTCCTCCTGGAAATGACTCTAGGGGGTAAGTGCTTCATCATGTAAGATGAGTATTTTTCACATTT TGTTGTGTCTGAAATCTGAGTGTGTCTTTCAATGATGGAATCTTTGATTCCATGATAAGTGGTATTATTC CCATTTTAAGGATGAGGAAACTGAGGTCCAAAGAAATTAAGTAATTTGCCCAAATTCACCCAGCCTAGAA AATGATAAAGCTAGTTCTAAACCCAAGCAGATTAGCTCTGAAGTCTGGGCCCTTAATAACCACTTTTTAT TGCCTATATTTGTACCTCTGGTGTACGTATCAAGTTATATGTTGACTTCAAAACTATCATGACCTTTTCT TGGTTTTGATTGTCCAACATTAGTATAGTGTTCTGGGTCTGCAAAAATTTTGATTACTCATCTCATCTGT AAAACATTTTGAACTCGTGTGTTTGTGCATGCACATTTGTGTGTAATTATAAAAATTTTACTTTCTGTTA ATATATAAGTTGTATCATAAGAAACTGCCGTTTTTGAAGAGCAAAAAAAGGTTGAATGTTACCAGTTACA TCTGGTTCAACCTAATAGACATTTGTACAAAAACAGACATTTTAAGAGGTTGAAATAAAAATTTAATAAA CAATATTTTCAGTTTTTACTAATTGTGATGCTTCACTATCATTAGCTAATATGTCAAGGCATAATATACC TTAGGGTGAACTTTATCATTAACAAAGGTGGATGGTGTCAATAATCTTGAGGTTTGTGTTTTTTTATATA ACACTGCGAGGTCTAATTAAGTACTTACTGTTTACCACCTCATACAGTGGCCGATAAAAAGTGTCACTTC TGCTGTTTCCTCTGGGTTGTGCTTGAATTATTAGTATTATCTTCAGTCCTCAGTTTCTTTGTGGGAAACT TTTTAATTAGTTGTTTAATTTTGTAAGATGGTTAGTTTAGTCAAAATTAGATAAGAGAATTTGAAAATCC GTAGCTACCCCAAAGCAACCTACACATAAGAACTATTATTTTTGTGTTTTGAAATCATAATTTTATTGAT TTCCAGTGTTTCCACTGGTAGTGGTTTCATTGATATAGGAGTATCAAAACATCACTCATTATTTATTTCA GTTTCATTTGATCCTAGCCGTTTTGTATTAACTCTCTGTGAAGAAATTACCTCACAAATCTATTGCTGTC CTTGGTAAAGGAATGGAGAATTAAGGCTCTAGATCATTAGTGGTTACACTATAGTATTAGAAGTAAAAAA AAGATTATACCAACAAAATAAGAACATGTTAATGTACTTGTAATGAATAAACATGAATAAAGCTCTTATG CTATATAGGTGCACTAAACAATCTACTAGAATTGTCAGCAAACTACGTATCTTAATCCTGAAAGGGTCCC AAACCAATGATCTAAAATTGAATCAAACTTTCTTCCTTGAGCATAATTACTTAAATGATTTATTAAAATA GCCAGCATTTAAAAGCTTAAAATGTAAATATCATAATGTGGTATCCTAGATAGCATCCCAGAACAGAAAA AGGATATTAGGGAAAAACTGGAGGAATGGAATAAATTATGCAGTTTAGTTATTAATAATGTACTAACGTC CTTAGTTATGACGATTGTACCATGGTAATGTAAGATACTAACAATAGAGGAAACCGGGTAAGGAGTATAC AGTAACTCTATACTATCTTTGCAACTTTTTTGTAAATTTAAAACTTCTAAAATAAAGAACAAATTTAAAC ATTAAAAAGTATCACCAGGAACATATATCACTGTTTACAGATGAAATACTATGTATTTTCATATCTAATT TCTGATCATTGACTTCAAATCAGAAAAGTGAATGACACCTCAAAATCAGGTTTTCTGTTTACTGAAGTCT AAGAAAAGAAAGCATACCAGCTGGAGAGATTCATGTTTATAAAGACAGATTTATAACAACAAAAATAAAA TATCCAAGAATAAATTTAAGAAGAAGCACTTTACTGAGAAACATATGAAAACCTGAACAAATGGAGAGGG ATATTTTGTATTTGAATAGAAAGACTTCTGGTTTAAAGATAATTCTCTTTAAATTATTTTTTGTAGAAAT TTAAGGGGTACAAGAGCAGTGTTGTCACATGGATATATTACATAGTGGTGAAGTCTGGGGTTTTAGTGTA AATTAATCTTTACATTTTGTTTGAGCCCAATAAATGTACCAACATGATTTTTATAGAAAGATAGTCATTC CTATTAATCCAAACTTGTCCCAACTTTGAATTGAATTGAGGCAGAGCTAGCAGGTGTTCCCCACGGCTGA GGCATCTGAACATTAAGCATATCCCTCTGAGAACCAGCCTGCATTGATACTCTTTCTAATGTGGACAGCA TCAAGCTATGTACGTAGTTCTGTGCTCAGCAAAAGCCCTGACTTCTTTTTGTTTATGTCCTAGCCCCATA CAACAAAATCAACCAAAGAATTTTGGTTGTGGATCCAGTCACCTCTGAACATGAACTGACATGTCAGGCT GAGGGCTACCCCAAGGCCGAAGTCATCTGGACAAGCAGTGACCATCAAGTCCTGAGTGGTAAGACCACCA CCACCAATTCCAAGAGAGAGGAGAAGCTTTTCAATGTGACCAGCACACTGAGAATCAACACAACAACTAA TGAGATTTTCTACTGCACTTTTAGGAGATTAGATCCTGAGGAAAACCATACAGCTGAATTGGTCATCCCA GGTAATATTCTGAATGTGTCCATTAAAATATGTCTAACACTGTCCCCTAGCACCTAGCATGATGTCTGCC TATCATAGTCATTCAGTGATTGTTGAATAAATGAATGAATGAATAACACTATGTTTACAAAATATATCCT AATTCCTCACCTCCATTCATCCAAACCATATTGTTACTTAATAAACATTCAGCAGATATTTATGGAATAT ACCTTTTGTTCCATGCATTGTAGTACTCATTGGATACACATAGAATAATAAGACTCAGTTCACACTCTTC AGGAAACAGATAAAAAACTAAGAAACAAACAAAAAACAGGCAATCCAACACCATGTGGGAAATGCTTTCA TAGCCGGGAAACCTGGGGAATACCTGAGAGGAATACTCAATTCAGGCCTTGTTTCAGGAATCCAAATCCT GGCACATCAGAGCTGCTTCCCTCTTTCCAGGGTGGCAGGAAATAAATGGAACATATTTTTCTATCTTATG CCAAACATGAGGGACCCTTTCTCCCCGGTGCCTCTCCCAAGGTAGTCTACAATATTTCAACTCTAGCAGT CTGCTTAGTGCATAGAACATGAGGCTGTGTGTCCCTGGGCAAATTACTAGACTTCTGTGTGCTTCACTTT CCCTGTAGGATTATAATCTACTGAGCAAGCTTATTGTAAGGGTCAGATTAGCAACAGTGTATGAAAATGA TTTGAGACCATTGCCTGCACAAATTCAACTATTTTTTTTTATCTCACTACTCTACAGAAGTAGGTAGGGT GGGAGACAGAGTCTGATGAGAGGCTCAGAATGTGAAAGAAAGTGAGGCGAGTGAGCATGATATTTAATAT AAACACAAAGATATTCTGAGAAGAGCTGCTCACTGCCCCCTCCCCCAATACATGTTGATAGGAAAATGCC ACGTACTTCAGCAAAAACAACTGAAAAATTAGATAGAAAAGTCAATCAATAGGAAAAGATAATCCAGGAC GGTGTTGTGAACAGAAAGAGGGGGAAAAAACTTTAGAAAATGATGGGGATGCTCTTACTGGGGTACGAGT CCTCAGGTATTGAACTGGCTTTCAGTAAAAGCTAGATTAGTGGGTTCCTGCCATTTACAAGCTGTTTTAT GACAACTTACTTGTTGGGTGGCCTACAGTAACTCACCTAACTGCACTGAGTCTGTTTCCTCATCTGTAAA TTGGGGATTTTTTTTTAAATACCTGGCATGCCTAACTCATAAAGTTGTTCTGAAACTGAAATAAAACATA CGTGAACAGGCATTGTAAACTGTAAGTTACGGAAAAAGCTGGCTGTTGTTGTGTCTTTAAAGTTTCACCT GGGTAGTCAAAGATGGATCATGGGTCTCAGTGGAGAGCTGAGCCAGGCAGGAGCTGACTAAGGGTGAGAG GTGGGAGTTAGCAGCCTCTGAACATCTGTGTACCATGGGACCCCCTTTCCTCCTGCATGGTACCCCAGAC AAGGAGCCTAGTAAGAGATACTAATGGCTTGTTGTCCAGAGATGTTCAAACTGCAGAGAAAGATAAGACA ACAAGCATTGGCCTCCAATCATGATGACAGATAGGAGGAGGTGGGAGCTCCTTAGCAGTGCTGGTTGGCC TTCCATGTTCTACTGTGGGCCATCTCTGCCATGTACTGTAGGCTACTAGCTTCTATATTAAAGAATGCAA GAGGGGCCAGGAGCGGAGGCTCATGCCTGTAATCTCAGCACTTTGGGAGGCCAAGGTGGGCAGATCACTT GAGGTCAGGAGTTTGTGACCAGCCTGGCCAACATGGTGAAACTCTGCCTTTACTAAAAATATAAAAATTA GCTGGGTGTGGTGGTGTGCACCTGTAATCCCAGCTACTCGGGAGACTGAGGCACAAGAATTGCTTGAACC TGGGAGGCGGAAGTTGCAGTGAGCCCAGATTGCGCCACTGCACTCCACCCTGGGCAACAGAGAAAGACTC TGCCTCAAAAAAAAAAAAAAAAAGCAAGAGGAAGTGAAATAATCAAGGCCGCCATTTAATAGTGAGCAGC CACTCCATGTGGTACTGTGCAAGCACATTATAAATATTAGCCTCACAAGAAATGTATTAGCATTTGTATT TTGTACACTGGTTAAGTATCTTGCCCAAGACCTCAAAACTGGTTAAGGGCAGCAGAATTTAGCCCCAGCA CCACCTTTTCAAAGCCTGGGCTTCTCACACTTCTCCATGCTGTTCCCATTTTAACACAGGTATCTCGCCA TTCCAGCCACTCAAACTTTGGCATTTAAGAAAATTATCCTAAAGCTAAACTAAACTTCAAGGATGACCAT TCTCCTGACCCCTTCCCATCAAAATTTTATCTTTAGTCAGTTTGTTTTCGTTTTGTTTTGTTTTTCAGAA CTACCTCTGGCACATCCTCCAAATGAAAGGACTCACTTGGTAATTCTGGGAGCCATCTTATTATGCCTTG GTGTAGCACTGACATTCATCTTCCGTTTAAGAAAAGGTAGTATTTCCTTAATTGCAGTGGTCTCCACTGG GGGTGAGGAAGGGGTGAGAATTGGATCATGGCTGCAAGGAAACCCGACTTAACCTCTGCAAGGTGGTGCA AAGGCATTCCACTGTTCAACAGCAATTATATTGAAGCTGAGTGGGATCACTGGGTGAAGATGAAGCGTAA GGGGTGAGGGGCAGGAGAATGGGTATGGATGGAGGTAGAAGATGCAGTGTCATACAGTTTTTTTCTATCA TGAAAATAACCACAGACTTACAGAAGAGAAAGAGCTAAAATGCCCGTCATTTTCAGTTGCATTTTAGTCT TGCATTAGTTGCAACCAGCTGGTTTCTGGGTACCCTAAGTAATAAAAATAGTTCCTCTGTAGAACTGTAG TATGTTTACCATAGAGTATTTTGCAAAATTTTTGGTAGAGGATGTTACATAATTTGCATGTGTTCATTTC TCCATTTACCTGTGGGAACAATTAAAATCCAGGAAAATGAGTATATTCAAATAATTTCCTCCCATTTAAG ATGAGTCAGAGTAAATAATTCCTCCAATACTTAGAGAAGTATACCAAGAGATCCAGTGATGGTATAGAGT TGTCTGATGTTAAATAGGGAAGTAGAATATGGAAGGGGATTCCAATAGTCGTTGAAAAATTCCCCATAAC CCCTTACATGGGGGAAAGTAGTGTTAACTGAGAGAGTAGAGATAAGCTGTTTCCAAAAATTATATTCTTA ACAGGACTGAGATAGCCAGAATATAAGGATCAAGTTTCAATGACAGTAAGATCCTGAGATGGAGTTGATT TGCACAAAGAAATAATTGTTGCCAGCATGCATTTTGAATATTTCTCTGGAAAAAAAGATTAGTTGGCAGT AGAAATGGATAGAAATCAATAGATATTAAAATACCTCAGAATTTGGTTCATCTCTGGGAAAAGATGAAAA ATAAAAGTGTATACTCCTCAAGAACATCTAGGATCAAAAGCATGTGCCCTACACTATTGAATTAATTAAC CTCATAAGTTGGGACCTGTGGAATAAGGATGTCCACCAGACTTCCTAGGGATTACAAATGTTTCACAGAA CTTGAAATTTAAACTTGGGTCACTGTATGGGATGTAGAGCTGTGCTATATGGAAATAAAAATGATTTCTT TTTCTCAAGGGAGAATGATGGATGTGAAAAAATGTGGCATCCAAGATACAAACTCAAAGAAGCAAAGTGG TAAGAATATCAGAAGGAATTGGGAAGTAAAAGTCAAAGGAAACAAAAAGCTAAAGCAATAACAAAGAGAA ATCCATCAGTCATAATCTCCTCTCCTTTTAAAGAATGCTGGTTCCCCTTTGCCTCACAGCTAACACAAGA ACTCCTCCACCGTCTGAGGAGGTTTAGGAGCAGGGAAGGGGAAGGAGTCAGCTTCATTTGCTAATCTTCT GTTGCCCTGCACCCTAGCAGCTCCTTGCAGCAGGGGACAAGGATGACTTAGGTGGATGGATAATTAATTG ATTCTAAAATATTGTGTGTCAGTATTGTAATACTATGTTAATTGCACCATGCACGGTATCTCATTTAATC CCCCACCCCTTGCCATTACCAAAGAGAGAGAGAGAGAGAGAGAGAGAAATACTAGAATTTATCCTCATTT TACAGTAGAGAAAACAGAGGGTCAAGAAGATAATGTAAAGTGCCCAAGAACACACAGCTGATCACAAAAA TCAAGCTTGGGGGCCATTAGCCTAACCACAGACCCTTACTCTTAACCCATCTGCTTCAATCCATTTTGCT ACAAATGTTTACATTTATAAGCAGGGCAGAAAAACCTCATCCAGGTTATTGAACTAAGAAGAAAGTTATA TTAAGGTTTCTAATTTTTTTAATGTAGTTAGAAACCAAACTTAACAATGAGCCCAAGTTTAAAGCAGTCT AATTAACCTGGACAAGCTCAGGCAAGTTTCATTCTGTGGCCCATAGCATCATCTGTGTTGTAAAGCTAAG TAGCAAATGTTGTTTGGGTCATGCTGGGGGACAAGCCATCCCAATTTGCTCAGGACTGAGGGGTTTTCCA GGATATCATGTAAGGATAATTGGGTACAAATATAACCTGCTGCTTTCTCTCATTTCAAATTTATCATTTA TCATATCAGCAACTATGAGTTATGTTTTTTATTAGATTTCTTGTTACTTTTTCCCCAGACCACTTCCCAT GAAATTAATATACTATTATCACTCTCCAGATACACATTTGGAGGAGACGTAATCCAGCATTGGAACTTCT GATCTTCAAGCAGGGATTCTCAACCTGTGGTTTAGGGGTTCATCGGGGCTGAGCGTGACAAGAGGAAGGA ATGGGCCCGTGGGATGCAGGCAATGTGGGACTTAAAAGGCCCAAGCACTGAAAATGGAACCTGGCGAAAG CAGAGGAGGAGAATGAAGAAAGATGGAGTCAAACAGGGAGCCTGGAGGGAGACCTTGATACTTTCAAATG CCTGAGGGGCTCATCGACGCCTGTGACAGGGAGAAAGGATACTTCTGAACAAGGAGCCTCCAAGCAAATC ATCCATTGCTCATCCTAGGAAGACGGGTTGAGAATCCCTAATTTGAGGGTCAGTTCCTGCAGAAGTGCCC TTTGCCTCCACTCAATGCCTCAATTTGTTTTCTGCATGACTGAGAGTCTCAGTGTTGGAACGGGACAGTA TTTATGTATGAGTTTTTCCTATTTATTTTGAGTCTGTGAGGTCTTCTTGTCATGTGAGTGTGGTTGTGAA TGATTTCTTTTGAAGATATATTGTAGTAGATGTTACAATTTTGTCGCCAAACTAAACTTGCTGCTTAATG ATTTGCTCACATCTAGTAAAACATGGAGTATTTGTAAGGTGCTTGGTCTCCTCTATAACTACAAGTATAC ATTGGAAGCATAAAGATCAAACCGTTGGTTGCATAGGATGTCACCTTTATTTAACCCATTAATACTCTGG TTGACCTAATCTTATTCTCAGACCTCAAGTGTCTGTGCAGTATCTGTTCCATTTAAATATCAGCTTTACA ATTATGTGGTAGCCTACACACATAATCTCATTTCATCGCTGTAACCACCCTGTTGTGATAACCACTATTA TTTTACCCATCGTACAGCTGAGGAAGCAAACAGATTAAGTAACTTGCCCAAACCAGTAAATAGCAGACCT CAGACTGCCACCCACTGTCCTTTTATAATACAATTTACAGCTATATTTTACTTTAAGCAATTCTTTTATT CAAAAACCATTTATTAAGTGCCCTTGCAATATCAATCGCTGTGCCAGGCATTGAATCTACAGATGTGAGC AAGACAAAGTACCTGTCCTCAAGGAGCTCATAGTATAATGAGGAGATTAACAAGAAAATGTATTATTACA ATTTAGTCCAGTGTCATAGCATAAGGATGATGCGAGGGGAAAACCCGAGCAGTGTTGCCAAGAGGAGGAA ATAGGCCAATGTGGTCTGGGACGGTTGGATATACTTAAACATCTTAATAATCAGAGTAATTTTCATTTAC AAAGAGAGGTCGGTACTTAAAATAACCCTGAAAAATAACACTGGAATTCCTTTTCTAGCATTATATTTAT TCCTGATTTGCCTTTGCCATATAATCTAATGCTTGTTTATATAGTGTCTGGTATTGTTTAACAGTTCTGT CTTTTCTATTTAAATGCCACTAAATTTTAAATTCATACCTTTCCATGATTCAAAATTCAAAAGATCCCAT GGGAGATGGTTGGAAAATCTCCACTTCATCCTCCAAGCCATTCAAGTTTCCTTTCCAGAAGCAACTGCTA CTGCCTTTCATTCATATGTTCTTCTAAAGATAGTCTACATTTGGAAATGTATGTTAAAAGCACGTATTTT TAAAATTTTTTTCCTAAATAGTAACACATTGTATGTCTGCTGTGTACTTTGCTATTTTTATTTATTTTAG TGTTTCTTATATAGCAGATGGAATGAATTTGAAGTTCCCAGGGCTGAGGATCCATGCCTTCTTTGTTTCT AAGTTATCTTTCCCATAGCTTTTCATTATCTTTCATATGATCCAGTATATGTTAAATATGTCCTACATAT ACATTTAGACAACCACCATTTGTTAAGTATTTGCTCTAGGACAGAGTTTGGATTTGTTTATGTTTGCTCA AAAGGAGACCCATGGGCTCTCCAGGGTGCACTGAGTCAATCTAGTCCTAAAAAGCAATCTTATTATTAAC TCTGTATGACAGAATCATGTCTGGAACTTTTGTTTTCTGCTTTCTGTCAAGTATAAACTTCACTTTGATG CTGTACTTGCAAAATCACATTTTCTTTCTGGAAATTCCGGCAGTGTACCTTGACTGCTAGCTACCCTGTG CCAGAAAAGCCTCATTCGTTGTGCTTGAACCCTTGAATGCCACCAGCTGTCATCACTACACAGCCCTCCT AAGAGGCTTCCTGGAGGTTTCGAGATTCAGATGCCCTGGGAGATCCCAGAGTTTCCTTTCCCTCTTGGCC ATATTCTGGTGTCAATGACAAGGAGTACCTTGGCTTTGCCACATGTCAAGGCTGAAGAAACAGTGTCTCC AACAGAGCTCCTTGTGTTATCTGTTTGTACATGTGCATTTGTACAGTAATTGGTGTGACAGTGTTCTTTG TGTGAATTACAGGCAAGAATTGTGGCTGAGCAAGGCACATAGTCTACTCAGTCTATTCCTAAGTCCTAAC TCCTCCTTGTGGTGTTGGATTTGTAAGGCACTTTATCCCTTTTGTCTCATGTTTCATCGTAAATGGCATA GGCAGAGATGATACCTAATTCTGCATTTGATTGTCACTTTTTGTACCTGCATTAATTTAATAAAATATTC TTATTTATTTTGTTACTTGGTACACCAGCATGTCCATTTTCTTGTTTATTTTGTGTTTAATAAAATGTTC AGTTTAACATCCCAGTGGAGAAAGTTA Download Select all
Length	20187
OMIM ID	605402
HGNC ID	HGNC:17635
Unigene ID	Hs.521989
Ensembl ID	ENSG00000120217
PharmGKB ID	-

mRNA Information

mRNA ID	XM_006716759.2
Exon	join(1..216,5720..5785,6699..7040,12454..12588, 12695..12741,15119..15226)
mRNA Sequence	>29126 GGCGCAACGCTGAGCAGCTGGCGCGTCCCGCGCGGCCCCAGTTCTGCGCAGCTTCCCGAGGCTC CGCACCAGCCGCGCTTCTGTCCGCCTGCAGGGCATTCCAGAAAGATGAGGATATTTGCTGTCTT TATATTCATGACCTACTGGCATTTGCTGAACGCCCCATACAACAAAATCAACCAAAGAATTTTG GTTGTGGATCCAGTCACCTCTGAACATGAACTGACATGTCAGGCTGAGGGCTACCCCAAGGCCG AAGTCATCTGGACAAGCAGTGACCATCAAGTCCTGAGTGGTAAGACCACCACCACCAATTCCAA GAGAGAGGAGAAGCTTTTCAATGTGACCAGCACACTGAGAATCAACACAACAACTAATGAGATT TTCTACTGCACTTTTAGGAGATTAGATCCTGAGGAAAACCATACAGCTGAATTGGTCATCCCAG AACTACCTCTGGCACATCCTCCAAATGAAAGGACTCACTTGGTAATTCTGGGAGCCATCTTATT ATGCCTTGGTGTAGCACTGACATTCATCTTCCGTTTAAGAAAAGGGAGAATGATGGATGTGAAA AAATGTGGCATCCAAGATACAAACTCAAAGAAGCAAAGTGATACACATTTGGAGGAGACGTAAT CCAGCATTGGAACTTCTGATCTTCAAGCAGGGATTCTCAACCTGTGGTTTAGGGGTTCATCGGG GCTGAGCGTGACAAGAGGAAGGAATGGGCCCGTGGGATGCAGGCAATGTGGGACTTAAAAGGCC CAAGCACTGAAAATGGAACCTGGCGAAAGCAGAGGAGGAGAATGAAGAAAGATGGAGTCAAACA GGGAGCCTGGAGGGAGACCTTGATACTTTCAAATGCCTGAGGGGCTCATCGACGCCTGTGACAG GGAGAAAGGATACTTCTGAACAAGGAGCCTCCAAGCAAATCATCCATTGCTCATCCTAGGAAGA CGGGTTGAGAATCCCTAATTTGAGGGTCAGTTCCTGCAGAAGTGCCCTTTGCCTCCACTCAATG CCTCAATTTGTTTTCTGCATGACTGAGAGTCTCAGTGTTGGAACGGGACAGTATTTATGTATGA GTTTTTCCTATTTATTTTGAGTCTGTGAGGTCTTCTTGTCATGTGAGTGTGGTTGTGAATGATT TCTTTTGAAGATATATTGTAGTAGATGTTACAATTTTGTCGCCAAACTAAACTTGCTGCTTAAT GATTTGCTCACATCTAGTAAAACATGGAGTATTTGTAAGGTGCTTGGTCTCCTCTATAACTACA AGTATACATTGGAAGCATAAAGATCAAACCGTTGGTTGCATAGGATGTCACCTTTATTTAACCC ATTAATACTCTGGTTGACCTAATCTTATTCTCAGACCTCAAGTGTCTGTGCAGTATCTGTTCCA TTTAAATATCAGCTTTACAATTATGTGGTAGCCTACACACATAATCTCATTTCATCGCTGTAAC CACCCTGTTGTGATAACCACTATTATTTTACCCATCGTACAGCTGAGGAAGCAAACAGATTAAG TAACTTGCCCAAACCAGTAAATAGCAGACCTCAGACTGCCACCCACTGTCCTTTTATAATACAA TTTACAGCTATATTTTACTTTAAGCAATTCTTTTATTCAAAAACCATTTATTAAGTGCCCTTGC AATATCAATCGCTGTGCCAGGCATTGAATCTACAGATGTGAGCAAGACAAAGTACCTGTCCTCA AGGAGCTCATAGTATAATGAGGAGATTAACAAGAAAATGTATTATTACAATTTAGTCCAGTGTC ATAGCATAAGGATGATGCGAGGGGAAAACCCGAGCAGTGTTGCCAAGAGGAGGAAATAGGCCAA TGTGGTCTGGGACGGTTGGATATACTTAAACATCTTAATAATCAGAGTAATTTTCATTTACAAA GAGAGGTCGGTACTTAAAATAACCCTGAAAAATAACACTGGAATTCCTTTTCTAGCATTATATT TATTCCTGATTTGCCTTTGCCATATAATCTAATGCTTGTTTATATAGTGTCTGGTATTGTTTAA CAGTTCTGTCTTTTCTATTTAAATGCCACTAAATTTTAAATTCATACCTTTCCATGATTCAAAA TTCAAAAGATCCCATGGGAGATGGTTGGAAAATCTCCACTTCATCCTCCAAGCCATTCAAGTTT CCTTTCCAGAAGCAACTGCTACTGCCTTTCATTCATATGTTCTTCTAAAGATAGTCTACATTTG GAAATGTATGTTAAAAGCACGTATTTTTAAAATTTTTTTCCTAAATAGTAACACATTGTATGTC TGCTGTGTACTTTGCTATTTTTATTTATTTTAGTGTTTCTTATATAGCAGATGGAATGAATTTG AAGTTCCCAGGGCTGAGGATCCATGCCTTCTTTGTTTCTAAGTTATCTTTCCCATAGCTTTTCA TTATCTTTCATATGATCCAGTATATGTTAAATATGTCCTACATATACATTTAGACAACCACCAT TTGTTAAGTATTTGCTCTAGGACAGAGTTTGGATTTGTTTATGTTTGCTCAAAAGGAGACCCAT GGGCTCTCCAGGGTGCACTGAGTCAATCTAGTCCTAAAAAGCAATCTTATTATTAACTCTGTAT GACAGAATCATGTCTGGAACTTTTGTTTTCTGCTTTCTGTCAAGTATAAACTTCACTTTGATGC TGTACTTGCAAAATCACATTTTCTTTCTGGAAATTCCGGCAGTGTACCTTGACTGCTAGCTACC CTGTGCCAGAAAAGCCTCATTCGTTGTGCTTGAACCCTTGAATGCCACCAGCTGTCATCACTAC ACAGCCCTCCTAAGAGGCTTCCTGGAGGTTTCGAGATTCAGATGCCCTGGGAGATCCCAGAGTT TCCTTTCCCTCTTGGCCATATTCTGGTGTCAATGACAAGGAGTACCTTGGCTTTGCCACATGTC AAGGCTGAAGAAACAGTGTCTCCAACAGAGCTCCTTGTGTTATCTGTTTGTACATGTGCATTTG TACAGTAATTGGTGTGACAGTGTTCTTTGTGTGAATTACAGGCAAGAATTGTGGCTGAGCAAGG CACATAGTCTACTCAGTCTATTCCTAAGTCCTAACTCCTCCTTGTGGTGTTGGATTTGTAAGGC ACTTTATCCCTTTTGTCTCATGTTTCATCGTAAATGGCATAGGCAGAGATGATACCTAATTCTG CATTTGATTGTCACTTTTTGTACCTGCATTAATTTAATAAAATATTCTTATTTATTTTGTTACT TGGTACACCAGCATGTCCATTTTCTTGTTTATTTTGTGTTTAATAAAATGTTCAGTTTAACATC CCAGTGGAGAAAGTTAAAAAA Download Select all
Length	3349

CDS Information

Location	join(5734..5785,6699..7040,12454..12741,15119..15226, 16390..16449,17460..17482)
CDS Sequence	>lcl\|NM_001267706.1_cds_NP_001254635.1_1 [gene=CD274] [protein=programmed cell death 1 ligand 1 isoform b precursor] [protein_id=NP_001254635.1] [location=109..639] ATGAGGATATTTGCTGTCTTTATATTCATGACCTACTGGCATTTGCTGAACGCCCCATACAACAAAATCA ACCAAAGAATTTTGGTTGTGGATCCAGTCACCTCTGAACATGAACTGACATGTCAGGCTGAGGGCTACCC CAAGGCCGAAGTCATCTGGACAAGCAGTGACCATCAAGTCCTGAGTGGTAAGACCACCACCACCAATTCC AAGAGAGAGGAGAAGCTTTTCAATGTGACCAGCACACTGAGAATCAACACAACAACTAATGAGATTTTCT ACTGCACTTTTAGGAGATTAGATCCTGAGGAAAACCATACAGCTGAATTGGTCATCCCAGAACTACCTCT GGCACATCCTCCAAATGAAAGGACTCACTTGGTAATTCTGGGAGCCATCTTATTATGCCTTGGTGTAGCA CTGACATTCATCTTCCGTTTAAGAAAAGGGAGAATGATGGATGTGAAAAAATGTGGCATCCAAGATACAA ACTCAAAGAAGCAAAGTGATACACATTTGGAGGAGACGTAA Download Select all
CCDS ID	CCDS6464.1

Protein Information

Protein ID	NP_001254635.1
Protein Name	CD274 molecule
Molecular Wt. (Da)	17991
Protein Sequence	>29126 MRIFAVFIFMTYWHLLNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGK TTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLV ILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET Download Select all
Length	176
Uniprot ID	P05787
Ensembl Protein ID	ENSP00000293308

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
5133	PDCD1	2590	NP_005009.2	in vivo	1 289 327 612 719 480

Pathway Information

Pathway Name	Pathway ID
Cell adhesion molecules (CAMs)	hsa04514

Structure Information

PDB ID	3BIK
Resolution	2.65
Method	X-RAY DIFFRACTION
Chains	A
Molecule	Programmed cell death 1 ligand 1
Model	View

Domain Information

ID	Location	Description
cd00098	153-210	IgC
cl11960	153-210	Ig superfamily
cd05713	66-114	Ig_MOG_like
cl11960	66-114	Ig superfamily
pfam08205	135-211	C2-set_2
cd05712	19-141	Ig_Siglec_N
cd05714	33-119	Ig_CSPGs_LP
cd05716	27-131	Ig_pIgR
cd00096	152-223	Ig
cd05900	33-130	Ig_Aggrecan
cd05877	33-119	Ig_LP_like
cd05846	33-114	Ig1_MRC-OX-2_like
cd05878	78-130	Ig_Aggrecan_like
cd00099	99-128	IgV
cd00096	37-120	Ig
pfam00047	33-115	ig
cd05901	81-122	Ig_Versican
smart00406	68-114	IGv
cd05731	152-194	Ig3_L1-CAM_like
smart00410	24-130	IG_like
smart00409	24-130	IG

Ontology Information

HPRD ID	1016
Molecular Class	Ligand
Molecular Function	Structural molecule activity (GO:0005198)
Biological Process	Cell growth and/or maintenance (GO:0008151)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO