Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| GTF2F2 | 2963 | General transcription factor IIF, polypeptide 2, 30kDa  | 13 | BTF4; RAP30; TF2F2; TFIIF  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22968445    | 2012 | Cell line : - Source : Department of Pathology of Wrocaw Medical University. Sample Type : - No. of Sample : - Stage : - | Laser capture microdissection,FFPE-FASP,SAX fractionation, LC-MSMS,Label-freequantitation. | Up-regulation | 2.3 | - |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | General transcription factors |
| Description | -   |
| Chromosome | 13 |
| Location | 13q14 |
| Start | 45120464   |
| End | 45284889   |
| Strand | +   |
| Gene Sequence |    Download   Select all |
| Length | 164426   |
| OMIM ID | 189969    |
| HGNC ID | HGNC:4653    |
| Unigene ID | Hs.654582     |
| Ensembl ID | ENSG00000188342    |
| PharmGKB ID | -    |
mRNA Information
| mRNA ID | XM_011535052.1 |
|---|---|
| Exon | join(1..258,16270..16343,29307..29325,31224..31368, 62938..63015,86961..87042,132408..132507,146770..146913, 162979..164426)   | mRNA Sequence |    Download   Select all |
| Length | 1469   |
CDS Information
| Location | join(193..258,16270..16343,29307..29325,31224..31368, 62938..63015,86961..87042,132408..132507,146770..146913, 162979..163098) |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | - |    
Protein Information
| Protein ID | NP_004119.1 |
|---|---|
| Protein Name | General transcription factor IIF, polypeptide 2, 30kDa |
| Molecular Wt. (Da) | 28249 |
| Protein Sequence |    Download   Select all |
| Length | 249   |
| Uniprot ID | Q13887 |    
| Ensembl Protein ID | ENSP00000366915   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 248 |
| S | Phosphorylation | 142;- |
| K | Acetylation | 33 |
| K | Acetylation | 137 |
| K | Acetylation | 22 |
| S | Phosphorylation | 76 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 405 |    ARNT |    524 |    NP_001659.1 |    in vitro |    8794892    |
| 1054 |    CEBPG |    738 |    NP_001797.1 |    in vivo |    8628277    |
| 1385 |    CREB1 |    442 |    NP_604391.1 |    in vivo |    8628277    |
| 1386 |    ATF2 |    443 |    NP_001871.2 |    in vitro |    8628277    |
| 2353 |    FOS |    1275 |    NP_005243.1 |    in vitro;in vivo |    8628277    |
| 2960 |    GTF2E1 |    1799 |    NP_005504.2 |    in vitro |    11113176    |
| 2961 |    GTF2E2 |    1800 |    NP_002086.1 |    in vitro |    967   742   311   113   176    |
| 2962 |    GTF2F1 |    1803 |    NP_002087.2 |    in vitro;in vivo |    86   626   608   441   635    |
| 3725 |    JUN |    1302 |    NP_002219.1 |    in vitro;in vivo |    8628277    |
| 4488 |    MSX2 |    421 |    NP_002440.2 |    in vitro |    9265625    |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Basal transcription factors |    hsa03022 |    
Structure Information
| PDB ID | 1BBY |
|---|---|
| Resolution | - |
| Method | solution NMR |
| Chains | A   |
| Molecule | RAP30   |
| Model | View |
Domain Information
| ID | Location | Description |
|---|---|---|
| cd07980 | 5-118  | TFIIF_beta |
| cl02122 | 5-118  | TFIIF_beta superfamily |
| pfam02270 | 5-241  | TFIIF_beta |
| COG5090 | 6-247  | TFG2 |
Ontology Information
| HPRD ID | 4212 |    
|---|---|
| Molecular Class | Transcription factor |
| Molecular Function | Transcription factor activity (GO:0003700) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
