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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
GTF2F2 2963 General transcription factor IIF, polypeptide 2, 30kDa  13BTF4; RAP30; TF2F2; TFIIF 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22968445   2012Cell line : -

Source : Department of Pathology of Wrocaw Medical University.

Sample Type : -

No. of Sample : -

Stage : -

Laser capture microdissection,FFPE-FASP,SAX fractionation, LC-MSMS,Label-freequantitation.Up-regulation2.3-


Gene Details



Chromosome: 13; NC_000013.10 (45694631..45858240)

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Gene Type protein coding
Gene Family General transcription factors
Description -  
Chromosome 13
Location 13q14
Start 45120464  
End 45284889  
Strand +  
Gene Sequence

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Length 164426  
OMIM ID 189969   
HGNC ID HGNC:4653   
Unigene ID Hs.654582    
Ensembl ID ENSG00000188342   
PharmGKB ID -   

mRNA Information


mRNA ID XM_011535052.1
Exon join(1..258,16270..16343,29307..29325,31224..31368, 62938..63015,86961..87042,132408..132507,146770..146913, 162979..164426)  
mRNA Sequence

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Length 1469  



CDS Information


   
Location join(193..258,16270..16343,29307..29325,31224..31368, 62938..63015,86961..87042,132408..132507,146770..146913, 162979..163098)
CDS Sequence

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CCDS ID -



Protein Information


      
Protein IDNP_004119.1
Protein NameGeneral transcription factor IIF, polypeptide 2, 30kDa
Molecular Wt. (Da)28249
Protein Sequence

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Length 249  
Uniprot IDQ13887
Ensembl Protein ID ENSP00000366915  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation248
SPhosphorylation142;-
KAcetylation33
KAcetylation137
KAcetylation22
SPhosphorylation76

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                                                                                                                                      
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
405ARNT524NP_001659.1in vitro8794892   
1054CEBPG738NP_001797.1in vivo8628277   
1385CREB1442NP_604391.1in vivo8628277   
1386ATF2443NP_001871.2in vitro8628277   
2353FOS1275NP_005243.1in vitro;in vivo8628277   
2960GTF2E11799NP_005504.2in vitro11113176   
2961GTF2E21800NP_002086.1in vitro967   742   311   113   176   
2962GTF2F11803NP_002087.2in vitro;in vivo86   626   608   441   635   
3725JUN1302NP_002219.1in vitro;in vivo8628277   
4488MSX2421NP_002440.2in vitro9265625   


Pathway Information


      
Pathway Name Pathway ID
Basal transcription factors hsa03022


Structure Information


PDB ID1BBY
Resolution-
Methodsolution NMR
Chains A  
Molecule RAP30  
Model View



Domain Information




ID Location Description
cd079805-118  TFIIF_beta
cl021225-118  TFIIF_beta superfamily
pfam022705-241  TFIIF_beta
COG50906-247  TFG2


Ontology Information


   
HPRD ID4212
Molecular ClassTranscription factor
Molecular FunctionTranscription factor activity (GO:0003700)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO