CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
ANXA11	311	Annexin A11	10	ANX11; CAP50

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
21239504	2011	Cell line : - Source : Aberdeen colorectal tumour bank. Sample Type : CRC tumor and Normal tissue No. of Sample : 10 Stage : Duke Stage C	In vitro chemosensitivity assay, Clinical association analysis, Cell viability assays.	Polymorhpism	-	The candidate marker LIFR rs3729740 and possibly ISX rs361863 will hopefully predict responsive patients to cetuximab regimens.
18071363	2008	Cell line : - Source : Asan Medical Center,Seoul, Korea. Sample Type : CRC tumor and Normal tissue No. of Sample : 118 Stage : -	2-D Gelelectrophoresis, MALDITOF MS, Immunohistochemistry	Up-regulation	-	-

Gene Details

Chromosome: 10; NC_000010.10 (81914880..81965328, complement)
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Gene Type	protein coding
Gene Family	Annexins
Description	This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, May 2013]
Chromosome	10
Location	10q23
Start	80152610
End	80205677
Strand	-
Gene Sequence	>gi\|568815588:c80205677-80152610 Homo sapiens chromosome 10, GRCh38.p2 Primary Assembly TTCCTGGAGCAGCTCCGCAGCCGGAAGGCTGCTGCTCCTCGCGGGCCCGCCGTGCCCAGTCCTCATCTTG GGGGCGGGGCCGCGCTCAGGCCCCGCCCCTCCCTTGCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGC GGAGTTTTCCGCCCGGCGCTGACGGCTGCTGCGCCCGCGGCTCCCCAGTGCCCCGAGTGCCCCGCGGGCC CCGCGAGCGGGAGTGGGACCCAGCCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGA GCCACTCCCGCCCACGTCCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGGTGAGTGAGGGTCCC GAGCCGGCTGGGGGCCTGGGACCAGGCGGCGGCAGTGCACCGCGGCGCCGCGGGTGAGGCCCGGGGCTGC CTGGCGCCCAGCCCAGCGCGGCCCTGCGGCTTCCTGGTTGCACTACAGGCGTGGGGGTGGGGGGCAGGGG AGGGCGTCGGCGGGTCGCGGGCGGGCCGTGTCGGCCTGGCAGCCCCCTAGATCAGCCTCGGCGTCTGGGG CTGCTCCCTCATGTGTGGTCGGGGTGCACTCGCCGTCCCCCCGGGCTCAGGGGTCGGGGTCTCAGTCTGG GCCTGGGTAGGGCCAGGGGCCGTGACCCTGGGCGCAGGAGGCAACGGGTGGCGGGAGGGGTGCCGGAGGC CCGGCCCCGCAGCCCTGCGGAGCCCTCCAGGGTGCGCGCGCCCTTCTAGGCGAGGCTTGGGGAGATTAAG CAGAGAAGGCTATCTTCAGGAACTTTCCTCCGAAACTGGGAGCACGCACATTCCTGGGAGCTGCTACCAT TGCAGTTTATTTGTAAGGAACTCTCCCCAGTGTTTGAGGGAATGCGGGAGCCATCCCAGGTGCTGTGCGT GCCTTCGCCCCTTCCCCAACCTTGATCCCCAGTTTCAGGAAGGGATTCCTGGACTTGTATCTCCCATGGG TGCAGGCCAGGCCCTTAAGACTTAGGTAAAATGGTCTGTTGGTTTAAAGGAGACACGCGAAGTTTGTTAC CTAGAGACTTTGGAGGGGAAAAGTTAAGCCAGCCAGTGCTAGCCCAAGCTGGAAACAGTCAGCCCGGGGC ATTTCTGTCTCTGCCCTCCAATCCTTGACCTCTCTGTAGAGATTCGGCGTTTGTGGTAGCTCTCCCCTCT GTTCTCTGCGCTGGGCATGGAGTGGAGCTGTGAGGCCGAGCCCCTGCCCTGCCCTGCCCTGCCCTGCCCA CGCAACAGGGACTAGGTTTGCAGGGCAGGGCCTGGTATGCTCACCCTTCACTGGCTCTCATTGCTTTCCT CATTCCTTTTATGCGGCAGTCAATTGTTGGGGATTCCAGGGGATTAACAGGGCCCCTTTCCTCAAGGCAT TCTTTGTGCTGCAAGGTGTTCCCTGATAAGAGAGGCCAGGTGAGGTGCCAGGGCAGTTTGTTGCCCTGGC ATTGGGTGCCCACTACTTCAGGCTCCTGCATACCTTGCTATCTTTTCTTTGACTATTGTCTGTGCTTTGG TTTTTCATCTGTAAAATGGGGGTAATAGTAATCCCTGCCTCACAGGCTTGTGAGATTCAGTGCATTCATT TATTTAATAACAATACAGAGCTCAGGTACGGACCAGTCAGAACAGGTGGTGACTGCTGCACCACACTTGT GTATCCCAGATGGGTGTCACCCACATTAGCCATAAAGTGTGTGAGGCAGGCCTGGGTCATAAATAATCAG GTGTAAGGGTCAATAAATAGTAGCAGTGGAAGGTTCAGCTAAAGTTGAAATGCACTTCTCCTGAACCGTC TTTCTGGCTTAGCTCATGCTAAGCTCATGCTCTCTGTCTTACTGGAATGCCCTCCCTCCCCTGTCTGGCC TAGCATTCTCCACCCTCCTGGGAGCCATCCGGGTGCCTGCTCCCAGCAGGAGGGACGGGATATGCTCTGA GCTCACTCAGCCCTTCTGGCACTGACTCGGTTCTCATCTCTCGCCTTGCATAGTATTTGTGTGGCGGTGT GGCTTATCGCTGCCCTGTCCTCTGACTCTGGAGGGTGGGGGCTGTTTCTGACTTACCTCTTGGTGGCAGC ACTCAGGATGGGCCTTGCCTAATGTAGGTGCTCAGAAAATTAGTTGTCGTTAGTTGAACAACAGAGACAG CACAGGGAAGTGGTTTCCCTGTGGTTAAAATATAGGACCTTGAAGGCTGGGTTTGGATAGAGAAACGTGG GGAGGGTGAGATGGAGATGAATTGGGACTAAGAGGTGGGAGTGGAAGCCTCACCTGACGCCTTTATGCAT GATACTATAGAAAGGGCCCACCCTGGGTGGATGTGTCTAGAAGGCCAGGATCGATTAGTGATGCCTAGTT CACGTGATTGGGGAGGTGATGTGTGGCTTGGGATGACAGGAGTGGGAGTTGAGACAGAATAGGTTAGTGT GGGTTCTTCTTGGAAATTGTAGAATAGAGAAAAGAAACTGGTGTGGGCAGGAGCTGAATGTGGAACCAAA ATGCATGCTGAATGCTGGAACATCAGAGGTCCTGGGACCTTTCTGGTGCACCCCCTCCTTCCTCCTGGAT TCACCCCTCTTCTTCTGCTGTCTTTTTTTTTTTTTTTTTTTTTGAGACAGATTTCGCCCTGTCACCCAGG CTGGAGTGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCTCCCTGGGTTTAAATGATTCTCCTCCCT TGGCCTCCCGAGTAGCTGGGATTACAGGCATGCACCACCATGCCCGGCTAATTTTTGTATTTTTAGTAGA GACGGGGCTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCTGCCTCAGTC TCCCAAAGTGCTGGGATTACAGGCATGAGTCACCGTGCCCGGCCTCCTCTCTCTTCTTAGCCACTGTTTT CCCCCGTAAGCCTGAAGCAGTTCCTGGCACTTGTTCCCATGGGGAAGCGTCTGTGTAAGGGTATGCTTCA CCAGCACTGCCAAGGAAGTAGACTTTTCACTTTCTCTGGATTTTTCTCTGCAACACCCTCTGATCCCATT GCCCCCAGAATAGTAGGAATTTTGAGTGATACCTAGATAGGAAAGCTCTTAGGATTAATGAAGAAACTGA GATTTTCTTGGTGGGAGTTTGTGCTTTTAAAGGGAGTTGTTGCAATTCAATGGAACTCTGTAATAACCAC TGAAACTGTTACACATTAGGCTTACTGACCCTATCTCCTATAACCCATGAAATAAAGACCTGATAGTCAC ATAGTTGTTTGCTATTTGGGAGGATCCTAAAAGTACAGCCTGAACAGTGACCCAAACCACAGCTGGCCTT GCCCATGCTGATGTGAGGAAGGAATGGGTGGGGGCAACTAAGAAATTGGGGGACAGAGTTCTCTGTGCTA GGTATCCTAGGACAAGCCACCCAGCCACACAGAGACCCCCCGCTTCCCCCCCACAGAACAGTTCTGGATG ATAAAATGCCTGCCTGGAATGGAGAATCAGATGAGAAGATGTTTGCAAAGGGGTTTGAGATCAGTTAGCG GGTGGTGATGACAATGTTGATACCGTGGGTGTGTGACTGCCAGGAGCTGTGAAGCAGAGGGTGGAGTGTG CGGTGGTCAAAGCCTGGTTCTGGGATCTCTAGCTTTCCAGGGGCTTAGGCTCCGCCTTAGCAGAAAAGAA GGAAAGGAAATTGAGAAGGAAGTCAGGTGTCCCCTGCCCCTCACACTTGGGGATGGCTGACTTGGAGGAC ATGAGATGGGGGAAATCTGAGTGAGGGCAGAGAAGAGAAATGTGGAGGCTGCTCACAGGGAGGCTAGGGA GCATATGGCATATCCAGCCTGGGGAGTGGCACCACTGGGGGAAAGGGTGCGTGTGACAGTGGGGAAGGAG TGGTGATAACAGATGTGAGCTTGCTGTGTCCACTAAAAAGGTCACGGCTATTTTTAGGAAGTAGGTGACA AGGCATGTTCCTGTAGAACTGCTTATTACTGAGAACCCACTGTTGGCCTCGCCCTGCGTGGTGTGCTTAA AAGGAGAGACCGCCCCCACTCACCCTAGAGTCATCCACCTGGTGTCCCTGAGACATGGGACACTGGATGA GGACCAGGTTTGGAGGATGAAGAAGATCATGTATTTGGTTTTGGACATGTTGTGTTTGAGGTGTCTTTGA GATACCAAATAAGCTGGTGGGTCTGGGGCTCAGGAGGCGTCTTGGCTAGACAGACATTTGTCTAGGTTGT GTTTGTATTTGAAGTCATGGGCACAGCGAGATTGAAGAACTCACCTCGAACAGCTGAGTAAAGGAAGATG AGCCTATAAAGGACCCAGAAAAAGAGCGACCTGAGAGGGGCCCAGAAAGCCAGGACAGAGTTGTATCCCA GGGGCCAGGGTGAGTCTGCTTCGTGGGATGGAGTGGTCAGCTTGGCATCGCGGCTGTGGTGAGTGATATG GAGGAGATGTGGCTGCCTTCACTGCTTTGGTGGGATGATGTGAGCAGAAGCGAGGTTGGAGTGAATGGGT GAGGAGTAGCAGGACGTGAGGATCTGATGATAGACAGGCTCTGAAATGTTGGCTTTGAAGGCGAAGAGGA CGTCGTTGAGGGAGTGTTTGATTCTGTTGCCTCGATTTACCCTCCTGCTCCCTTTCCAATCCCAGAAGGG AACATGTGGATGGCCTGCCACTGACATCCCTCCCCACGGCGCTCCGTGCTCAGGCAGACCTAGGTACCTG CAAGGGTTTGCTTCTTTCACAAAGTGGATTCATTCTCATGAATGAATGAATGAGTGAATGAAGCATGTTG CCCAGGTTGGTCTCAAAGCCCTGGCCTCAAGCAATCCCCCCGCCCCGCCTCAGCCTCCCAAAGTGCTGGG ATTACAGGAGTGAACCACTGCACCTGGCTGGTATTAAATTTTCTTTGTGGCCAACTGCATGATAAATATT AACATGTTTCATGGGCGTGAAAGGAGAAAATAGGTCCTCTGCGGGACGCTGACTTTAGATAGATCTCTTA ACTTCAGTTACCCTTATATCCCTGCTTGCCTGGCTGTCAGATTCTGAGAGGTATAACAAAAACTCTCACT GTAGTTTTTTAAAGTCCAGCTCTACTTATATTTGTGGGAGTTCTAGCCTTTTGAGTTTGGCTTTCGTGTT TCATGTATATAGGCTTATCAAGCTGATCTTCCTACCTGTCATTTGCTGGTTATTTAATGCCTTTGGTCTT TGGTCTTAAATTCCATATTGTCTGTGTTTTAGGAGAATACATGGCCAAGGATCTGGGAGAATCTCTTTTC TTTACAGTCTTAAAATTAATAAATAAGTGCATTTTATAAGATAATAAGTGAAAGGCTCAGAAATTTAAAT GCAGGCATCAGAGGACATTCAAGCCATGCCCCTTTAGCTTCTGTTCAGGCTCACATGGAGCGGTTAGTAA TCAGGTCTCACTGATGACCATGAGCTCCCTGTCCTTGGCTGTCCTAATGGTTCCCATGATAGCCAGATTT TTAGGAGGGGTGGATAAAATGAGATTTGCGTGCAAACTCCTGGGACGTTGCCTGGGAACCTCTTCTCTCA CTTTGCAATTCCTGCCCCTTCCTGTAGGTCCAAGAAGCGGACTGCTCTGCCTCTCATTTACGCATTTCCT TCCTCATTCCAGACAGCAAGATGAGTTTTTGACAGAGTAGCCAGTACAAACACTTCTCAGGGCCAGAAGT CAGAAAGACGCGGGCCCCAAGTCATAAGCTCATCTCTGTGCTTGTGTTTTAAGCCACATAAACTGTCTCA GCGGGCTGGACTAGGCTATGCCTTGTTGTACCCTGAGATCCTAGTGAGTAGTTCTCCAAGTACTGTGTTT ACAGATAAAGGCAAATGCCAGAGAGAAATGGCTGGAAAAACCCCTTGGCTTGCTAAGGCAGGATTATCGA AAAGTCTTCAACATATATGTTTTTAAATTTTACATATTTTTTCATTTTTATTTATTTTGAGACCAGACTA ATTTTTGTATTTTTGGTAGAGATGGGGTTTTGCCATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAA GTAATCTGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACGGACATGAGCCACTGCACCCAGCCAACCAC TGTGCCCAGCCTATTTTTACTATTAATATTTCCACCTCTGTTTTTCTTTGCATTTATTTGGTATGTCTTT GCCCAACCCTTAGTTTTAAATATTTCTTTCTCACTTAAAAAAGTTTATCTTGGCTGGGCGCGGTAGCTCA CGCCTGTAATCCCAGCACTTTAGGAGGCCGAGGCGGGCAGATCACGAGGTCAGGAGATAGAGACCATCCT GGCTAACACGGTGAAATCCCGCCTCTACTAAAAATATAAAAAATTATCCAGGCGTGGTAGCGGGCGCCTA TAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGGAGGCGGAGCTTGCAGTGGAG CCGAGATCGTGCCACTGCACTCCAGCCTGGACGACAGATCAAGACTTGGTCTCAAAAAAAAAAAAAAAAA AAGTTTATCTTGAAGATGGAATCTTCGTAAATAAAATTTGTTTCTCTTATAATCAGAACGTGGTTGAGGG TGGATGGAGGTTGACAGAAGGCAATGATAACAGCAACAAACCTAATTGCATGGTTTCTGTCTTTGGTAGA GGAATTCTGACTGTTGACATACCAGATATACTTGATTTTATTCTTTGCATCTTGCTTATTACTTATTATA CTTGCATGCATTCCTTTCCTGATTTTTGCTGTTGGGTTAAGTTTCTCATCGTCATCTTCCCCACGCCACC TGTATTACGTTTCAGGTTTGGTTGTGAATGAAGAGAGGAGCCCCGTCTCTCTCTCTCTCTCTCTCTCACT CACTCTCTCACTCTTTCTTGAAAAATCAGGGTCGAGGTTAAGTGTGTGTTCCATGAGATTGTCTTGGCAC CAGGCTCCTTATGGACTGTTGTCCCTAGCATTCTCAAGGGCTGTGGTTTTCAAACTTGAGCATGTATAAG AACAATCTGGAAGGCTTGTTAAAGCATAGATTCTTGGACTGCACCCTGAATCATTCTAATTTAGGAGGTC TGTGATGGGACCTGAGCACGTTAATTGCTTACAGGCTCCCATATTGTATAATGCCGCCGGGCCACATGTT GGGTAGCACCGTCTAGGTGCCTCCCTTAACTGCATGGCCCAAGACAGCTCACTTTCACATCCCCATGGCA GGCCCTCCTAGCTGCTAGGGGTCTGGAAAGCAGTCCTTAGTGGGGGCTGCTGTGTGCCAGGCTATGGTGT GTTCTGTTACTAAAGCAAGAGAGAACAGATGGTTGAGGAGGACAATCAGAAGTTTCTGGAACACCACCCA CTGCTCTCCTGAATTTGAAACTACTACTATGCTTATCAGTCTTGCTGTTGGCTAAGCCTGTGTTCCTCAG GTTAGGAAGTGGGAATGGTTTCTCATGACAGTGGCAAGCCCGCAGGCAGTGCAAGCAAGGCAGCTTCTGT TCCTGTGGGCTGGTGCACAAGCTGGCAAGCTGCTGTGGCTTTGCTGATGCCCCGAGAGTCATCTGCTGCT CCCAGCCGTCAGGTCTGGCATCCGCATACTCCATTGCTGCAGCCACCACCAGATCTTCCAGACCCCATGG GATCGAGGGGCCCCCTCCAAGACCCAGTGGGATAGGGGTTATTTTTTTTTTTTTGAGACGGAGTCTCACT CTGTCGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAAGCTCTGCCTCCTGGGTTCACGCC ATTCTCCTGCCTCAGACTCACAAGTAGCTGGGACTACAGGCGCCCGCCACTGCGCTTTGCTAATTTTTTT TGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCC TCCCGCCTCGGCCTCCCAAAATGCTGGGATTACAGGTGTGAGCCACCGCGCCCGGCCAGGGGTTATTTTT TTGTGCTACCTCCTCCCAACTTCCCTTCTTCAACCCCAAATATGACACCTAGGTGACTGTTTCTAGGAGA GTTTGAGGGCAGAGGCTATTTGAACCCTGAACTGAGGTGGGGGTGATGTTCGGTCTCCGTGGCTGGTAAT ATCCTTGAGAGATCAGAGCAGTGGTTGCCAACCCCCATTCTCTGTTGTCATCACACATAGGGAGGGGATC TGGAGAGAAACAGGGTCATAAGGCTCCTATGGAGTGGCTGGTACTTTTCTGAGTGGCTTGATTATATGGG ACATTATTTGGGAGGCAGTAGTAACTTTCTTCTCTTTCCGGGGTTTAACCTTTGTATTTCTCAAGTCCAT TCTCCAGCCTGAGAAGGTGTGATGGAGCCCAGAAATACGTTGAGTGGTTGGGGACCAGCCTGGTTCATAA TGCACTGGCCTGGAAATCCAGAGATGTGGTTCTAGTCATTGTCCTGCCCCCAGCCAGCTCTGAGACCTCA GGCAGAGTCTTTCTGCTCTCTGGGTCTCAGCTCCCACCTCAAATAAAATAAACAGGTTGAATGAAATGAT TTCATGAAGGCCCTTTCCAGCTCCAGTATTTTAGGATTCTTATGTAATCCAAATGCTAGTGCACTGGGAA TTGACTTTATCTTGAAGAAGTGTCTTTCAGAACCTGCTTGCTCAAGTTCAGCCCCTTGGTGAGGCTCCGG ACGCTGCCACTCTCCCAGCCTGCCTTGTCTGGAGTTTCTCCAGGCTGAGCTGCCCCAGGTGCCAGCCCTC AGAGGGGAGGTCTGAGGTGCAGCCTGGCTAATGATTAACATACGCTACAGCTATTTTAGTTCCTGGCATG TGGGTGGGGAGTTGAATGCTTAACAGCACCTGTGTAGGCTTTTTGTTTAGTGCCTGGGAAAATATGGTCA GGGTTGGTGGAGTGCTGCCCTGAGGCTGGCTGGCTGGCTTCGGTGACTTAATGGCACCTGTGACCAGCAA GGGCAGGACATTGGGGCTCTGGAGTGCACGCCCAGGGCCCCCACCCCCTTCTCAGTAGAGCTGGAGATGT TCATACTCCCACTCACATCACTTAAGGTCCTGCCTTGAGGTGGGGGAGAGAGGGGAATGTCCTAGATGTG TCCTCCCTGCCCCCAGAATTCCTGGGGCCTACGTAATAGAGGCTACCGAAACAGGTGCCACCCAGAGAGT GAAAGAAATGAGTCAGAGTCCACCGGGGTTCCTGCCAGTATTCAGTATGTGTCAAGGGCCTCACAGTGCC AGCCCTGTGGCAGGTGGTGGTGGGGGACAGGAAGAGAGGCCTGTCCTACAGCCTGTAGCACTGATGCTCT CATGGGGAGGCCTAGAAAAAAAGTGTCTGGCTCTGGCACTTGGGTGTGTGACCTTTGCATGTCAAGAGTC AGCTCAGCCTTCGTTCCCTTGCTTATAAAATGAGGATGATAATACCTATCCAATAGGAGCATTGTGGAGG TTAATGAGGTAATATATAGGGATGTAATATATGTATCTATCCTAGGAGTTAGAAAAAGGAGAGCTTATTA GAACATTAGAGAACATGGAAAACATTTTAGGACAAGTGCTGTGAGAGTTCCAAGAAGAGTGAGCATTGTG GATAGGAGATCAGGGTGGGCTTCCTGAAAGAGATATGGTATGGTTTGGCTGTGTCCCCACCCAAATCTCG AATTCCCTCGTGTTGTAGAAGAGACTTGGTGGGAGGTAACTGAATGGGGCAGGTCTTTCCTGTGCTATTC TCGTGATAGTGAATAAGTCTCACAAGATCTGATGCTTTTATAAAGGGAAATTTCCCTGCACAAACTCTCT TCTCTTGTCTGCTGCCATGTGAGACGTGCCTTTCACCTTCAGCCATGATTGTGAGGCCTCCCCAGCCACG TGGAACTGTGAGTCCATTAAACCTCTTTCTTTTGTAAATTGCCCAGTCTTGGTTATGTCTTTATCAGCAG TGTGAAAATGGACTAATACAAGGTGGAACTTCATCTGGACTCAGGGAAGGCCAGGAGACAGGAGGTCAGA CCAGCTAGAGGGACCACCTAAGCAGAGGTGTCCTGAAAAGGGAAAGTGCTGAGCTGGGCTGGGCTAAGGA CATGCATTTTTTGTGCTTCTCTCCATCATGCATGTCCCTGAGGTACCTTCTGTTTTCATGCTGTTCCTCA GTGGCCCAGTGTGAGTGACTCTTGGCTCCAGACTGCTTGACACAGCTTAGGATGCCAGCTGCAGAAGGGT CAGCCCATTCCCAAGTGAAGGTGTTTTCTCCTCCAGAGTGAGCTGCAGGTCCTTGAACTTCCAGTTGCAT GCGGCTGACTGGGGACATTGTCACCATCTGAAGAGCAGACCTTGATAAGGGATATTTGGAAAGGTTTCCT GAGGCTTCTAGGTAGAGCAGGGGTGCTCAGCCATTTGGAGCTGGAATATACACTCTGTTAAGTCTCCCAG GCTTGAAGGGGCTGGGCTTCCAGAGTGGTTTGAACAGGCCCCGAGGACTGGCTGATGGGCATCAGGGCCT TTCCGGGAGAGGCTGGGGGACACACTGCTGCCATCACACTCTTCAGTCTTCTTCGCCTCTCTTCCTCAGC CTGTGGTGAGAGACGGGTCTGTGCCGGCCATTCATAAGGAGATGAGATGGCTCATAACACACCAACTGGA AGGGCCCTGGTAAACCTCTACTCCTGTGATCACAAATGCAGATTCCTGCAAGGACAGCCCGGCAGCTGAA GGAGGGAGGGAGGTGCGCAGCTGTTGCCAGCCCTAGCCGAGTGTCACCATGCAGAAATATGGGGCCCTTG TTGCCAGAGCTCCTGTTTTAATATTTTTGAAGGATTTAAGCCAGAGTCTCCCTTTTGCAGCCCTTTCCTC CCTCCAATGAAATAATGCTATTGAGCTCCAAAACCTTCAGGAGCCCCAGGTTCTGGGAGGCAGCATGCAA ACCACTGAGGCCCTGCAGGCGCACTCATTGAAAATAGGTGAGGTAGACGAGGCTGGGAGGGCTTAGATTT GCCAAGGCCCCTCAGAGAGAAGCCAGTTTCTCAGACGCCCCTATGCTCCACTGCCAGGGAACACATTTTC TGAATTCTTTGTCTTCCCCCCCCGACTCTTCCTAGGAGTGGCTCTTAAATATTGTAGTGTGTGTTTCCCT GGAAGTGCGCTATTGTGTTTATCTCGCTAGCTAGAGGGAAAGCATGATGCAGGCCAGGACTTTATTTTTT TCTTCCCTATCCTAGGGGGTGTAGCCCAGCCCCTGGTGCCTCCATAAACCCAGGTGGGATTGCTGTGAAG CTAATGAAGTGGAAGCTTCAGGTCCCCGGACTTGTAGCACCCTAGTGAGGGGCCGTGGGAGGGGCACTAG CAGTGAGTTCACAGAGTCATATGGTTTATAACATTTGCAAAAAACTAAGATTTTTTGTATTCTTTGTCCT GAAGAGGGTTCCTAAAATTGTATAAGCTTCAGGCCCCACAAAACCTGGACCTACTGCAGATGTTGGTACC AGTCTCACAGACTGGCTGCTAGTGTTTTATTTTAACTTTCCCCTAAAAAATATATGCCTGTTTTTTCAGA AAGCAGTTGAAGAATATAGTTCACCAGGCTGGTCAACATGGCGAAACCCTGTCTCTACTAAAAATACAGA AATTAGCTGGGCGTGGTGGCGCATGCCTATAATCCCAGCTACTTGGGAGGCTGAGGCTGCAGTGAGTCGA GATTGCACCACTGCATTCCAGCCTGGGTGACAGAGCAAGAGACTTCTTCAAAAAAATAAAAAAGAAGAAG AATGTAGTAATATTCTGTCTTTTTTTTTTTTTTTTTGAGACAGAGTCTCCCTCTGTTGCCCAAGCTGGAG TGCAGTGGCACGATCTTGGCTCACTGCAGCCCCAGCCTCCCGAGTAGGTGGGAGTATAGGCATGCGCCAC CACGCCAGACTACTTTCTGTATTTTTAGTAGAGACGGGGTTTTGACATGTTTGCCAGGCTGGTCTCGAAC TCCTGGCCTCAAGTGATCTGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCATTGCGC CTGGCAGAAGTAATGTTCTCTTTCTAAAGTTAGATGATAAAGGATGCTTATTTTATTGTGCTTTATAATT CATATATATGTTGTATTTATTGCTATATTGTAAAAATATTTTATAATAATACACGAAAAAAGCCAAATAT GTTGATCCAAAAGGCTTATAATGAAGCCAGCAGTCCCCTGACACATCCTTCCTCTTTCCCTTTCTCCAGA GTTAATCATTTTTAACTATTTTTAATTAATAGGCTTATATGACTGTTTCTTAATTTATCAGTTTTGAAAT ATGTTGACTTCCTGCTTGGTAGATTAGGAACCAATACATACATCAATATTTAATGTATGCATTATTGTGA CCATAAATTGTATTGTTCGATGCTGTGCAAGTAATGTGCCGTGGTCACACATTAGGAGTACAATCCTTCC TGTCCCAATATTCCTCAGGTGGATGCTTTCCCTCCTTGGGGGCCTGATTTTCTGTGTATCTATTGTTCCA AACTGGTCTGGTTGCTCCGCAGGCCTGCTGCTCAGCTGTTGTCCCGGGACTTCTTTTTACAGTCTTCTGT GTTAGATTCTCCTATTCCTAGATCCTATATATTTTATTTTCTTTATTTTCCTTATTTATGTCTCATTTTG CTGAAATCATCCAGAAGTTCCTAAGAAAAGTGCATGGGAGGTAGATTTTGTTTTGTTTTTTGTTTTTGAA GCTTGTGTGCCTGCAAATATCTCTATTCCTCCCTAATGGATAGAAATATCCATTCCAAATATCTCTATCC AGTAGTGGATAATTTAGCTGGCTATAGAATTATAAGCTGAAAATAATTTCCTTTCTGAACACTGAACACA TTATTCTGTTATCTTCTAGTTTCTAGTGTGGCTGTTGAAGTCCAGTGTCCTTCCAGTTCCCCTGAAAAGG ACCCTTGTTCTTTCTTTTCTAAAGTTTTAGTATCTTCTGCCTCTTCTCTTCTCAAATTTCACAATGATTG CTTTGCTGATCTTTTTGCTTTGTGGATATAACATTTTCTCTTCCGTCTCTAAGGATATTATTGATTATAT TTTTGTCCTCTATTTCTCATCATTGTCTGTTTCTTTGGTTCTCTTCTATCTCTGAGGATATTATTGATTA TATTTTTGTCCTCTACTTCTCATCGTTGTCTGTTTCTTTGGTTCCTTTTCTTCTGTTTTGGTCTCTCCCT TTCTTGGTGTAGACTTTCTCAGATGTCCTGTGACCCTTTGCTGTCTATATGAAGAGGGAGACCATAAAAA TCTGATTAGAGTGCATAGGTGAAATGTACAGGAGGGGCAGGATTTTATCACATCTCTTCCCCCTTCGGTG TGTTTCCTGGAAGGCAGTTATTCCCCAATATTGCAAAATTAATCTCTCCTCAGCGCTGGTCTTCCCACTG TACCTGCTGTTGCCTCGGGCAGGAAGCAGCAACCCAGGCTTGAACTCCCATGGGCTGCCCCCGTGATGGA ACAAAAAGAATCATCCTAGAGAACTGGGCCTGAGTCCGCCAGCAGCTCTGAGGACAGGAAGCCTCTCTAC CCACCCTGCCCTGGGGACGATGAGCTCTAGCCTGGGAGTGGGGGATTCAGCACCAGCCCTCTTAGGGTCT TGCTGTATCACCTTGGCATGCCACAACCCTCTCTCTGGTTGTCAGTGTGACCATTTGTGAAATGGGGTGA GGTGGGGTCGGTGGGAGTGAACTGAGTCGTCTCTGAGGTGCTGAGCTGGCCTCTGGCATCCGGTTGTGAG GTCCTGGCTGATGGGGTGTGATGGCCCTGCCTGTGCAAATCCGACTGGGCAAATGCTGACTGGGCATGCG TAGCCTGGCCACACGGAAGCCACTGAGGGCCCAAGTCCCCTGGTGACTCATGTTGATTGGTAATTCAAGT TAGCACACCTGTGCCGAGCCTGTTCCCGACACATGGGAGAGGCGAGCACCTGGTTCCTCCTTGTGCCGTT GGAAAGGGTTTTTTTTGTAGTCTTGGTGGTTTAATATTTCCCTTGTTGAAGAAAGCTGGCTGAGTTAGGT AGACATGTTCACAGAGCTCTTATGCAAAGAGAACAGAGGCCTTTGGAAAGAGAATGCCATAGAAGGATCT GGAAGGAAAGAGAAGGAATGGTCACTGTATATATTAGTTTTCTTTAAAGTTTTTTTTGTTGTTGTTTGTT TTTGTTTTTTGAGACAGAGTCTCACTCTGTCACCCAGGCCGGAGTGCAGTAGCACAATCTCGGCTCACTG CAACCTGTAGCTCCTGGGTTTAAGCAATTCCTGAGTAGCTGGGACTACAGGCACGTGCCACCATGCCTGG CTAATTTTTGAATTTTAATTTTATTTTATTTTGAGACAGAGGTTTGCTCTTTTTGCCCAGGCTGGAGTGC AATGGCATGATCTCGGCTCACTGCAGCCTCCACCTCCCGGGTTCAAGTAATTCTCCTGCCTCAGCCTCTC GAGTAGCTGGGATTGCAGGTGCATGCCACCACACCCAGCTAATTTTGTATTTTTAGTAGAGATGGGGTTT TGCCATGTTGGCCAGGCTGGTCTCAAGCTCCTGACCTCAGGTGATCCGCCTGCCTCAGCCTCCCAGAGTG CTTGGATTATAGGCATGAGTCTCTGTGCCTGGCCAATTTTTGTATTTTTAGTAGAGACAGGGTCTCACTA TGTTGCCCAGGCTGGTCTCAAACTCCTGGCCTCATGCAGTCCGCCCACCTTGGCCTTCCAAAGTGCTGGG GTTACAGGCGTGAGCCACCGTGCCTGGCCAATAGTTTTCTTTAAAAATTTTTTGGCCAGGCGTGGTGGCT CACGCCTGTAACCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACGAGGTCAGGAGATCGAGACCATC TTGGCTGACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAACTAGCTGGGCGCGGTGGCGGGCGCC TGTGATCCCAGCTACTCAGGAGGCTGAGGCGGGAGAACGGCATGAACTCAGGAGGTGGAGCTTGCAGTGA GCCAAGATAGGGCTACTGCAGTCCGGCCTGGGCAAAAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAA AAATTTATTGTAAATTAACATTTATAATTATGTAAATTTATGGAGTACAAAGTGATGTTATAATCTATGA ATACAATGTGAAATAAAGCAAACTAGTTAATATATCCATCACCTCAAATAGTTTTCAATAATTAGTTTTC AATTACTGCTGTAACAAATTACCACAAACTTGTGGCTTAAAACCATGCAACTCTTTTTGTGGTAAAAATA TACACAACGTAAAATTTACCATTTTACCCACTGTTAGGTGTGCAGTTCAGTGGTGTTAAATACATTCACT TCGTTGTGCAACAGTCATTACGATGCATCTCCAGAAGGTTCTCATCTTCCCAAACTGACTCTGTACTCAG GAAATGTAAACTCCCCATTCCCTCTTACCTGAGCCCTGGCCAACAGCAGTCTACTTTCTGTCCTTAGGAA TTTGACTCCTTTGGAGACTTCATATAGGTGGAATCAGAAGTATTTGTTCTTTTGTGCCTGGCTTGTTTCA TTTAGCATAATGTGTTGAAGATTTATCCACATTGTAGCATATGTCAGTTTTCTTCTGTTTTGAGGCTGAA TGATATTCTCTTTTTATGTGGAGATCTTGTTTTGTTTATCCATTCATCCATCAATGGGCACTTGAGTTGT TTCCACCTTTTGACTACTGTGAATGAGGCTGCTATGAACATGGGTATACAAATGTCTGTTGGAGTCCCTG CTTTCATTTCCTTTAGGTATATAGGTTGAGTATCCCAAATCTGAAATGTTCCAAAGTCCGAAACTTTGTG AGCTCCAACATGACGCTCAAAGGAAGTGCTCATTGAAGCATTTTGGATTTTGGATTTTTGGATTTTGGAT ACACAATGGTAAGTATGATGCCAGTATTCCAAAATCTGAAGTCATCTGGTCTGAAGACCACAATGTCTGA AACATTGCTGATCCCACACATTTTGAATGAGAGGTACTCGGCCTGTATGCCCAGGAGTGAGATTGCTGGA TCGTATGGTAGTTCTATGTTTAATTTTTTGAGGAATCTCCATACTGTTTTCCATAGTGGCTGCACTATTT TACCACATGGTTTTTTTATCTTTACAGTTTTATCTCAGGGTCTTTTGGATCTCATGGTGCTAAAATGAAG GTGTTGGCAGGGTTGTGTCTTTGTCTGGTGGCCCTAGAGGTGAATGCTTCCTTGCCCTTTCCAGCTTTAG AGGCCATTTGAGTTCCGTGGCACTTGGCCCTTTTCCTCCATGGGTGGAATCCCTCTCATGCTTGGACTCT GTCCTTCTTATTCTTCCTTTTCATCCTTAACCCAGCAACAAAGGCTCTCTGCTTTGAAGGACGCTTCTCA CTGGATTGGGCCCACCCGGATAATCTAGGCTAGTCTCCCCATTTCATGGCGGGTAACCCTAATCACCTCA GGACAGTCCCTTTTGCCACCTAAAGTAACGCATTCACAGGTACCGGGGATGTCTTTGAGGGACCTAATCA GAGAAGCTGATGGTAGCTGAGTTTCAGGCTCTGAAAAGCCCTCCCTCTACCCCTCCCCTTACCAGCATTT TCCTGAGGCCCCGGGACCCTAAGGGTTGGCTGGACACTCCCCTCACTGTGTGGGCTGGGCTGGTCCCCTG GCGGGAGCCTGACACCTGAGTTTAGTGTGTGCCCAGGATCTGTGACCCTTTTCTCCCTCTCGAAATGTCA GAGCCTGGCTTCTTTGGCCACTAGGCGTGTTGGTCACAGAGTGAAGATAACTGTGTCCTGCTTTACAAAG CGCGTTCCTGTTCTTTTTACTTTTAGTCCTCATAGTAATCCAAGGTAGGTGGGGTACATCAGGTCTTTGC AGATAGAATGGAGGTTCGGAGAGGTTAAGTTGCCCAGGGGGGTCACACAGCAAGCAGTTGCGTTAGGAAC CAGACCTTGGCTCCAGGCTAATGCCTCCTAGGGACTAAGTTAAAATTAACTGAGCACCTGCTGTGTGCTA ATACCTGTTGTAGTGCTATATATATATATATATATATATATATATATGTGAGAATACTACATTCTCACAG CTGTGTAATGAGATGGATGCATTTTTCCTCTTTTCACAGGTGAGGAGAAAGGCTCAGAGTGGTCAATCTA TATATCCAGGGTCACACAGCTAACAAGAGGTAGAGCTAGAATGGAATCATTGTCACTGGACTCCAAACCC TGTGTACCATCCCAGTGGCCTAGCAGCAGTGTTAGAAGATGATATCAGAGCTGTGTGGGCTGCGGTAAAA CTCATGCAGCAGAATTGAGAAGTCCCTTGTGACTGTCCTGTGATGTTTGGGGCCCTTGACGGGGGAGTGT GGGCCGTGAAAAGATGGGGGAGCTGGTTTAGAGTGTGTGAGAGAGAGTAATTGGGGGTGGTAGAAGCCTG CCAAGAATCTAGGGGTAGACATTGTGAAAGCCAATGTCAGTGAGGCTCAGGCCCAGTGTCTTGGAGCTGC AGAGCTTCCCTTTACCTCCCACTGCAAAATGAGGGAAGGGTTTAGAGAAGTTTCTGCTTCCTTCCGGCAG AGCTGCTGCAAGGGTTGTCTTGTAGATAGTAACTACCACAGGACTTGGGGTGTGGCACATCCCTGTGGGC CCAGGAGATCTGGGAGAAGCTGGGTTGGACTTTGCAGTAACTGGAGTGACCTGACAGCTAAGAGGGGTGG GATTGACAGGGAAGCCTCAGCCACCCTGGGACTTGTGCCCAATTGACATCAGCTCACTACCATTGTTTTG CTGGTCCCTCCTAGGCGGGCCCTGGCAGAAGCTCCCTCTGCTCAGGTGGTGTAACTGGCGGTGGCTTCCC CTTGCGGAAGTGGGTAAACAAAGACAGAGACCTGTGTCTCCTCCCCGCCCCTGCCACCTGCACTTATAAA CACAACCCACTGTTTCCCTTTTTGGGAGTGTGTGAGAGAGAGAGAGAGTGTGTGTGTGTGTGTGTGTGTG TGCACGCGCGCACATGCGCGTGCATCCTTAGGTTCCGTCTAAATCCGTTCAAGCTGCTGTAATAAAATAT CATAGACCGGGTGGCTTATAAACAACAGAAGTACATTGCTCACAGTTCTGGAGGCTGGAAGTTGAAGATG AAGGTGCCAGCAGACTCAGTGTCTGGTGAGGGCCCACTTTCTGGTTCACAAATAGGATAGCACCTTCTCC CTGTGTCCCCACATGGTGGAAAGGGTTGGGCCCTCTGGGATCTCTTTTATAAGGCCATGAATCCCATTCA TGAGGACTCCAACCTCATAACCTTCCAGAGGCCCCGCCTCCAAATGTCATCACACTGGGAGTTGGGATTT CAATAAATGAATTTTGGGGAGACAGAAGTATTCAAACTATAGCAGGTCCTGGCCACACTTTGGAGTCAGG ACTTGGGTGGGGGGCTTTTTCTGTCACTGCCACTGTGTCTGTTGCAAGAACCTCAGCGTCCTCCAGGACC TGAGTGCCCATCACGTGCTGGCCTGCGAGGCAGCCAGATATTAGCACTGTGTCTCTGTCACTTTCTTCCT CTGCTGCCCACTTTCCACTCCTCAGAAATTCTGAATTGGACTCAGCATTTGACTGAGCATTGGCTCTTAT GTGAGCCTGTTTGGTGTGGGCAGGCCTCAGAGGTGACTCTGCCCACAAAGAGGAGTGGCCTGGCTTCCAG GGAAGCCTGCCATGGAGGAGCGTGACGGAGAGATCTGCGTGTGACGCTGTGTGCTCTCGGTCTGCGTTGT ATGGAAAGTGAGTTCCTCCTCACTTGCCCCCATCCCCCTTCTCAGCACCTGGTCTGGAGAGGCAGGCAGG AGGAGAGAAGATGGCCCCATCCATGCCACACCTCAGTGAAAATTCTGAGGACAGGCTCTGGTGCCCGCAG GGTTGGAGCTTCATGCAGGCTGAGGCCCTGCCTCTGCGGGTCCCTCTCCCAGGCAGGTTTACTCTCCGAG GGTCTTTCATATCTCCCTGCCCGGTGGCCTCCCTCCACCATCAGTCTTGCCTTCGCTGTCCCCTCTACTC TTGGAGTGGAGCAGGCCCCCATACACCCAGGCACGTGGAGGGGATGGAAAGAAAACAGCGCCAATTTCCT GTTGGTGCTTTCTCTATTGGGAGGCTGGAAAATCCAACACAGCCATGCCAGTGTGCTCCCCACTCCCATC CTCCACCTGTCACACTGCCCTGACCCTCCCCAGTTCCGTGTTTCTCTCCTACCCCCCTCCTTCCCCCTTC AGTCCCCACAGTTCTCATCCTGGGCATTATCAAATAGCCCAGGGTCCTCTCTTTCTTATTTTGTTTTGGA GAAACAGGATGTCATGATATGTTACATGATATAATGGGAACAAACTTGGTATTAAACTGTTAATATCCCC ATTTTACAGATGGGGAAAACTGAGGTGCAGAAAGGTCTCGTAAACTGTCAAGATCGCGTTGCTGGTGGGG AGCAGGACTAGGATGTGAACCTGGGTAGTCTGGCTTCAGAGTCTGTGTTCTTCTCACCATCCTCCATTGC CTTTAATGAAGTACTTTAATGAAGTACCTTTAATGAAGTATGTAATGAAGTTTCATACAGTGAAACCGGA CTTAGAAGCCAGGTATCCTGATTCTGAATTCCATGCTATTTCATCATACCAGTGTTTCTAAAGCTCTGTT CTTAAAATACTAGTCCCTGGGGCCAGTGGGCTCTGTGAGGAAGTATAGTGTAGTGGTAAAGTCTGGGCTT TGGAAGCAGACTGCCTGGCTCAGCCATTCAATAGCTATAACCTTGAGCAAGTTACACAGCCTCTCTGTCC CTCAGTCTTCATTTCTGATATGAGAAGGATAATTTTAGTATTTGCCTCATAGGGTTGTTATAAAGTTCAG TTCCGTGTGAAGCACTTAACAGTGCCTGGCACATAGTAAGCATTTAATAAATGGTAACTACTATTATGGC CTAATTAGTTTGGGAAATTTGAGGATAGAGTTAAGCAGGCACTTTTGTTACAGGATTTATCAGAGCTTTT ATTACGCTGTTGCAAATTGGCAGTTTCCTGGAAAGGGGATGTGTAGTTATAGTACATAACTATATGTAGT AAGCATTTTCTAAACTTTTCGGGCAACTAATCTCTTGCTCTTGTCTGCCTGTCTCGCTCCTTAAACTGCG TGCCTTCTAACTTCACAACTTGTAAGATATGAAGCTGGTGTCAGGGAACACATTCCGGGCAGCACTGAGC TGCCCATCACTCTATCTGCTTCTAAGTGAGGCTGAGCTAGGCCTGGGCATCCCGGTTAGATCTGAGCAAG ACTTCTGGGGGCAGTAGATGGTAGGTGTTCAGAAGCAAACAGACTTATAGTGAAAATGAACAAGCTGTCC ATCAGTTGACTGTCATGCACCAGGTGGGTTCTGCTCTACAGAAGGCCAAAATGCATATTGTGGGAGTGTG ATGTCCTTGCTGAGATCCTTGGATTTATAAGTGTTTATTATGCTGTTCCTTGCCCTGCAGGCCAAATACA TCCTATTTGATACTTAAATAATCTCAGGAGCCAATGAAGGAAGAGGTTATAAAGGAGAAAATTGACTAAC TGGCAAAGCAGAGGCCAGTCCCCAGAACTCCATCCATTCTTCCACTCAAGCTGCATTTATGAGGTGCACA TTCAGCCAGATGCTGGGGTAACAGTGGTAAACAAGGCTGTGGGACTGCATTTTTGACTCTGGAAAACATT TGCAGATGGTTGGCAGCATCACCACTAGGTAGAGCTCAGTGGTCCTGGAAGAGTCCTGGGGAGGTTGGTT TTCTGGCCCTCTTGTATTGACAAGTGCCCCCTCAAGCATTCCAAGCTCATACTCTTCCTAAGGTGAATCA GCACCTGAGTCTTTTGCTGATGTAGAAGCCTGATCTCAACTTAGAGTCCCAGCTGTATTATAGTTATATA AACACACTGTCTGTCTGTCTGTCTCTCTCTCTCGTATTAGTTATATAAACACACTCTCTGTCTCTCTCTC ACACACACACACGGTCCCTGACTCAAGATGGTTGAACTTACAGTTTTTCAACTTTATGATGGGGTTACAT CACTTTCAGAAGGGATGTAACCAGCTCCTCCACTTTTGATGGGGTTACAATGAGGCTACGGTTTTTATTG AGTGCATGTCACTCTTGCACCATCATAAAGTTGAAAAATCATAAGTCGAACCATCATAAGTTGGGGACTG CTGTGTTGCCAGCATTAAATGCATTTTCAACTCATGATGGCTTTATTTGGATGTAACCCTATCATAAGTC AAGGAGCATCTGTATGTATTTATATTTAAAGTTCCTAACATTTAGAGATATGAACAGTTACAGATGAAAT AATATATGATGTCTGGGATTTGCTTCAAAACAATACAGGGGTGTGGGTGGGGTTCGGGATGAATCAAGAT GGGCCTTGAGGTGATAATTGTTGAAGCTGAGGGATGATGGTTTATTAAACTGTTCTGTTTTATATATGTG CTCCATAACAAAACTTTGTGAAAAAAGTCGACCATTATTAATCACCGCCTCTGTGATTAATGGATTAATT AGGATTGTGGCTCACTCCATGGAATTCCACAGCCACAGTTAGGTACATGGTCCCCTGGGGCCAGCTCCTG CCACTGAAGGGGTGTGTGGGGCAGAGCTTGGGCTCTATCTGCCTTCCCTCGTCTTCATAGTTATGGGGGA ACTGTGAGCTGATGCACTGAGGGTTTCTGGAACCTTCTGGCTGTGAGGAGTGGCCTTGGCAGACCCTTGT TTAAAGCATGCTTATTGCACTGTCTCCTTTTGCCCTTGGAGGAGGGGTCTTCAAGTAGGTTGCCAAGGGC AGGGCCCACTGGGACCACCAGTGAAGCCAGCTCAGCTTGGACAGAAGTGGCACACGTTTTGCAATGCAGC ACTGTGAGGGGATGTCAGGTTTTGTCGTCAGCTGCCTGCAGGCCAAGCTCTACCATGGACCCTCTCCGCC ACACCCGTGTGATGTGAGCAAGCCATGTCCCTGGTGTATTTTAGCTGCAAAGCTGAGGAAGTTAGAACAT GATCCCTTCCAATGTGGACATTTTGTGAGTCTGTAAGTCTAGGATTTGGGGTGAAAGCTGAAAGAGGCCC CCTTCAGAAATCCTGAGATCCCAGAGGAAGGAAGGACCTCAAAAAGGGTTGCCCCTGGTTTTGCCCATGG GTCAAGTGAGGTCTGGGAGAGGAGGCCTGGCCTCAGGTTGCTGGCTGAGATCCTTTTCTGGCTGAGATCC TTGGAACAGGACTACCGTAGTAGACGTTTCTGCCTCGTCTTAGACCTTCCATCTTGAGTTCTGGGCTCCA GGCCCTTGTCTGCACCTTGCTCTAGCCTGGTGCCTCCCTCTCTCCTGCCCAGTGACCTGGGACGAGTGCC TAGCCACTCACAGGGCACTGTGTGGAGGTCGTGAGCCACTCACATCAGCTCAGGGCTAAGTAAGTCTTCA TTTCCCCAGCCCATGCCAGGAGGGGCACCAGGTCGGAATGTGAACTAAGAAGGAAAACTCCAAGCAAAAC TCTCAACACTTCACCCTGCGACCAGATGTGTGTTTTTTTTCCCCACACTGACCAATTCTCTGACTCTAAC TGGGTGTCCTATAATGCAGCTCAATTCTGACCCTAACTGGAGTCACTGCAGACCCTATAGGTTAAAGGGC TCAGTCCCACAAGACTGCCAGATATATATTTCTTATATCACATTATCACCTGAGACATTACTTAACCAGA GCCGAGCCTTCTCCCGGAGTGAAGAGAGTTTGCAGATGCGTCAGTTTCTTTCCTCTTTTAAAAAAATTAT GTACATATATGGGGAATGGGAGGCCAAGGGAGGGAGAGCATTAGGACAAATACCTAATGCATGCGGGGTT CAAAACCTAGGTAACAGGTTGATAGGTGCAGCAAACCACCATGGCACATGTATAACTATGTAACAAACCT GCATGTTCTGCACATGTATCCCAGAACTTAAAGCCAAAACAAAATGTACATATATCTGAGCATGTATAAA CACATATGCATATACATTTATATATTTATGTAAATATATATACATGTATTATACATTTCTGTGTGTTTTA AACTGTACGTTGAAAACTGCTTGGTGGTGACCTTTGTGTACAAGGATAGAGGGAAGAATGCTTGCTTTTC ATTTTGTGTGTTTCTATTCTGTTTGAATTTCCCTACAGTGTGCTTGTATTCCTTTTATTTGTTAAATAAA ATTTATTTTTTAGAGTGGTTATAGATTTACAGCAAAATTAAGTGGAAACCACAGAGTTTCCCTGTCCCCC TGCCCCCACACTTGCACCCCCCGCCATTAGCACTCCCACCACAGTGGTATATTGTTACAATCAGGGAAGC AACATCGATCCACCTATTCATTCTTTCCTCCCCTGACCTCTGGCAACTACTCATCTTTTTGCTGTCACCA TAGTTGCTTTCTCCAGAATATCGTAGAGTTAGAATTATACAGTGTGTAACCTTGGGTGCTTCCAAATTGT TGGCCATTATGAATAACACTACTGTGAATGTCCATGAGCAGGTTTTGTGTGCGGCAGAAGTTTTCAACTT ATTTGGGTAAATACCAAGAGCATGATTGCTGGATCATTGGTAAAACTATGTTTAGTTTTGTAAGAAACCA CCAAACTGTCTTCCAAAGTGCCTATACCGCTTTACATCCCCACCAGCGATGAATGAAAGTTCCCGTTGCT CTGTATCCTCACCAGCATTTGGTGTTATCAGTGTTTTGGATTTTGGCCATTCTAATAGGTGTATAGTAGT ATCTTATTGTTTTCATTTGCAATTTATTAATGACATGTTGAGCGTCTTTTCATATGCTTATTTGCCACCT TATATCCTCTTTGGTGAAGTGTCTGTTCAGGTCTTTTGCCTATTTTTTAAATCGTAAGGTTTTCTTGTTG AGATTTAAGAGTTCTTTGTATATTTTGGATAATAGTCCCTTTATCAGATATGTCTTTTGCATTTATTTTC TCCCATTCTATGGCTTGTTTTTCCTTCCTTTCATTTTATTTTATTTATTTATTTTTTATTTTTTTGAGAC AGGGTTTCACTTCCATCGCCCAGGCTGGAGTGCAATGGCGTGATCTGGGCTCACTGCAACCTCCACCTCC CAGGCTCAAATGATTCTCCTGCCTCAGCCTCCTGAGTAGAGTAGCTGGGACCACAGTCGCATGCCATGGT GCTCGGCTAATTTTTTTGTATTTTATTTTTGTAACGACAGGGTCTCATTATGTTGCCCAGGCTGGTGTCA AACTTCTGAGCTCAAATGATCTGCCTGCGTCAGCCTCCCAAAGTGCTGGGATTATAGGCATGGGCCACTG TGCCTGGCCTCATCTTGTCATTTTAAAGAATATATCAGCAGGGATTATTGGACCTGCCTGGTTTAAACTA TTGTCTTAGTTAATTTTGTGCTGCTCTAACAAAATATCACAGACTGAGTAATTTATAAGCAATAGTAGCT TATTTGGCTCACAGTTCTGGAGGCTGAGAAGATCGTGAGGCTGCATCTGGCAAGGGCCTTCTTGCTGCTT CATAACATGGCAGAAGACATCATGCGGGTAAGAGAGAGCATGTTATACTTTTGTAACAAACACACTGGTG GTAAGGAGCCCACTTCCTCCATAACACATTAATCCATTCGTGAGGGTAGAGCCTCTTAAAAGTACCGCCT CTCAGAACTGTTGTATTGACCATTAAGTTTGCAGCACATGAACTTTGGGGGATACATTTAAACAATAGCA ATGATATATTTAAATTTTATGGATACAACCTTATGGGGAAAGTATTTTAAAAAATAAATTGTGTGTGTGT GTGTAAAAACAGGTTAAGGATCTAATGTTAAAAAAAAAAAAAACTAATATACAAATCAATATTCCAGCCA CCAGACTGGGGAAGGCCAGTGGAAAATCACTCCATGAAAGCATCCACTGTAGTCCCGGTCTGCTTGGTTT GCTGTTAGGCCCTGAGGGGCAGGGGGTGTCACTGCTGTGTGGCTTCTGGCCCGAGATGATGTTTCTAGGC CCTTGCCTCTCAGCATTAACCTGGTGTAGGCTCTGTTCCCAAATGAGCCCTGTGTTGTCTTTCTGGGGAG GACAGTCCAGAGTCCCAGGCATGGCACTGACACCATCCACCCCTCCTTTCCCTTCTGTATCCCTGAAGTC AGGCAGGACACCAGCAAATGTGCATGGCCTAGCCTTGCTGGTGGCTGGAGCCCATATCTCCACCTCCAAT TGTTGGGTAGAGACACAGCAAGGCTTCCCTTTTGGTAGGGGGATGACTGAGTCGGGGCAGTGAGGCTCTT CTTGCTCTGGCAGTTGCCTCCTGTCCCAGTGTAGCATTTCTAGATTCCTGTGTTAGGGGACTCCAGCTAG TACCCTTTTAGAGCCTGTGGAGTTGAATGGTACACTTACGTACACGTAACATGGCTTTAGGGAACAGGCC ATTTTGCAGCCACTGAGAAGCACCCCCAGATAGCTGCTCTATGCTTTTGGCATTCACCAGACGCTTTGAG GCTGGCTTCTGATGCAGTGCTGTCATGCCAGACTCCTGTCAACTTTAATAGGGATGGCACCATGTTTGAG AGGCCGAAGAAGAGACCCAGAGCCAACGAACAAGGCATAGGGCTTATTGAGGGGACTTACATATGGGGCG GTCCAGTGGCAGCAGGCTGGATGGAAGGACCACTACTATTTGTAAAAAGCATGCAGTTTGTATAGCATTT TAATTTAGCATCCTCCTTCCTAACCACCTCCACCTGGCAACCTTCATTTAACGCAGAACAAAGGGCCTTG ATCTCCTGTATGGCCATGGAATGGCTTAGGGGTTCTGATGTTCCTTATAGATAAGGAATGGATCTCCAGG TTGGCCACAGTTCCTCAGCTCAGAACTCTGAACACACATTCTTCTTAGACTATAGGGTCGTTCTGGGTAT GCTTAAGTGATTGCTGTCAGGTGCATCTGTCATACAACTGTGGGGGTGCCTAGGTCTAGTCTGTGTCCCT AGAGCTTACTATTGTGAAGAAGAGTATATTCGTCCATTCTCACACGACTATAAAGAAATATCTGAAACTG GGTAATTTATAAAGAAAAGAGGTTTAATTGGCTCACAGTTCTGCAGGCTGGGCCTATGCCAGGTTGAAGG GCCCAGAATATGGGAGCCAAGGTACCAGCATTTTTAGCCAGCTCTCCAAGTGAGGGAAAGCATGATGCTG GCATCTGCTTGGGGAGGCCTCAGGAAACTTACAATCATGTGGCAGGCAGATCTTAACCTGGCTGGAGCAG GAGGAAGAGAGGTGTGGGGAGGAGGCGCTACACGCTTTTAAACAACCAGATCTCACCAGAACCCTATCAT GAGAACAGCACCAAAGGGGGAAATCTGCCCCCATGATCCAGTCAGCTCCCACCTGGCCCCACCTCCAATG CTGGGAATTACAATTCGATTGTATTGTAATTAGAAATTACAATTTGGGCAGGGACACAAATCCAAACCAT GTCAAAGAGTGAGATCAGATGAGCTAGAGAGTGTCCAATACCTTAAGGGAAAGAGTGTTTCCTAGAGTGT GGACCACAGAACCAGTTACATCAGAATTACTGGGGACTGGGGGGTATGTATGCTTGTTTACACTTCAGAT TCCTGGGCCTATCCCAGGTTAGAAGGCCCAGAATATGGGGGCTAGGGCGCTAGCATGTTTAGTGAGCTCT CCAGGTGATTATCATGCATGATGAAGCAGTGTGGCCTGCAGGCAGGCAGCATCAGCATCACCTGGGAGCC ACTGGAAATGCAACTTTTTGGGCCCTGCCCCAGAGACACTGATTCAAAGACTCTGGAGGTGGGGCCCAGC AATCTGTGTTTTAACAAGCCCTATAGGGGACTGTTTTCCAGAAGCACCGATTTAACTGGAGAGGGCCCCA GCTGGATGAAATCAGGTGCACAGCTGCAGGTGGATGGTCGCAGTGAGGAAGGAAGGGCGGTATTTGTGCT GCAGCCTGCCCTGAGAGGCAGGACCAGAGGCCAGAAGGTCCCCAGAGACAGGTTTCTAAGAATTGGACCC ATCCTTAAGGAGGCCAGCTGCCTGCTGTGTGCAGGAGGCCCTCTCCAGTGAGTCCCCATGTCAGAGGGCC GTGATTAGAAGCAGGCGTAGAGCGGGGGACATGCCCCAGCCATCAGAATTGCACCAGCAGTGTGAAGCAT GTCTCTTGCCCCATGCAAGGAAAGGAGGAGAGAGGCATTGGTCAGGGTGAAAGGTATGATTCTCATGGAT GCCAGAGAGAGAGAGAGAGAGAGAGAGCAGATCTTCTGGATTATAGCTCACTGTGTTGCCTCTCTCCTGG GGAGTGGGTGCTGGACAGGCTAGGGAGGGGGACCCGAGGGCCTTAGAAGTCTTGCCGAGCCCAGATATGG CAGCCCTGGGGTGCCAGGAACGACTTCTCCAAGGACAGCCCCTTGCGGTAGCCTCTTTTGAAAAAATGCA GAGGTCACAGTTACCAGAAGACTGGACCATGAGCAGATTTCTTAATTTTCAAAGAAAAGGAGGAGAAGAA TGCTGCTTCTGTGAGTCAGAGAGCAGTGTGCTAATCCTGCAGCCTCTAGCCTCCTAGAACATGGATAGCT TGGGGGGAGATTGGTCAGCGCTGGGAGCCTGTGTCCACCTGAAGGTCACCCCTGGCTATTGGGCTGCGTT TACTTTTCTCCTGGGGGTAATTAGGCAGATAAACAGGCTCTCTTCAGAGTAAATGTGCTAGAACCCTCAC TTGGGCATGTGGAGAAATGTGTACTGGGTGGTGGCAGAGTGAGTTGGGGGAGAGCTGGTTAAATGCCTGC ACCCACATGATGCCTAGTGTTTGATGTTGAACTGGGGAGTTCTGAGTATGACAGTTCTGTAGTGTCCCTC GTTGTCCCTTTCGTCTTGGTTACTTGGCAGAACACAAATGCCATGCTTATTGCATCCATGGATGTAAAAC AAAGCTGAGAGAGAGGGGGAAGATGTTTGATGTTGAGCAGAATCCCAGAAGGTCTCAGGAGACTGGAGCA ATGGGCAGAACCCAGGGGAGAAATTTCACAGGAGCCCACATAAGGTCTCCGTGGCCTGAAAACCCACTTG TACCAGTCCGGGGAGGTAGGGAGTAGCATCCACTGGAGGGAGATGAAGGTCCCGCCCTGCACTCTTCAGA CCATACCTGGGGCGTTTGGTCCTGAAAAGAACTAAAAGATAAGAGTGGGGTCAGGCCAGGCATGTAATCC CAGAACTTTGGGAGGCTGAGGCGGGCGGATCATCTGAGGTTGGGAGTTCGAGACCAGCCTGGCCAACATA GTGAAACTCTGTCTCTACTAAAAATACAAAAATCAGCCTGGTGTGGTGGCAGGTGCCTCAGGTGCCTGTA GTCCCAGCTACTTGGGAGGCTAGGGCAGGAGAATTGCTTGCACCGAGGAGGTGGAGGTTGCAGTGAGCTG AGATTGCGCCACTGCACTGCAGCCTGGGTGACACAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAGTGG GGAGCAGGCTTGAAACTATTTCAGGCAGAGAATGACAGAGGGAAAAATGAGGCTATTCTTTCTAAGAACG GAGGACTAGAGGTATATCTTGGGGAGAGGGGAAGACCCAGGGTCGCAGGACCACAGCTCACAGTGGGGTC GACCTGCCCTGTGGGGCCATGCAGGGCAGAGCTCCTAGCCAGGAGGCAGATTTTGACTCCTGCTGGGAAC TCCCTTAAAAGCCACCCCAAGAATGAGCTCCACGAGCGCCATCAAGGCTGGCCTGCAGGCCCTCCAGGGT TACCAAGGCTGCCTGGAACTGAATGGACCCTGTGTGTGTTCTTTTAGTCTTGGAAGACCAGCCAGGACTT TGGGGGCCAGACGGCTAGCCTCAAGTGAGCTCAGAAATCTGCACCTGAATTGGGCCTTTTTAAAAGTTGT TTAATGGCCAATACATACATGCAGCAGAAATGCACAGGGAACAGATCTAAACCGGAAGCCTCATTTTCTA GCCCCACCTTTCCTCTCGAGAGGCAGCTAGTGTTAGCTAGTTTCTTGTGTGTCATTCCAAGGATGTCCGT GCACGTCTACACTCAGGAACCACTTAGTTTGTATGTTTCTGGGTTTTTTATTAGCTTAGTACATACACAG TACTGCACCTTGATTAATAATGGTGGTCATTGCATCTTTCCATATACAGAGCTGGCTAAATCCAGAAATA GCTACAGAGTATCCATTGTTGGATCTGTTGTGGTTTATTTAACCAGCCTCATTGGTGGAGGTTTAGGAGT TGTTGCAGATAAGGCTGTAGTAAAATTCATGTCTGTATGACATTTCACACAGGTGTGTGTCTGGGGAAGA GACTTACAGAAGTGGAGTTGCTGAGTCAAAGGTATGTCATTTTAAGTTTTGATATCTTTGTATTTTATTT ATTTATTTATTTTGGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCATAATCTTGGCTC ACTGCAACTTCCGCCTCCCAGGTTCCAGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGTATTACAGG CACCCACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAGTGTTTCACCATGGCCAGGCTGGT CTCGAACTCCTGACCTCAGGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCC ACTGCGCCCAGCCGACATCTGTGTATTTTTAATTGGTGATTTCCTCAGCACATTGGTGAAGGTGAGCATC TTCAGCTCCTTTTCTGTAACTGCCAGATCTGTTCACATCATTTGACAGTTTCTCTAGTGGTTATTGATCT TTTTCTTATTATATTAATAAAACTTTTTTCCTAAGTTTTTTTCTCATCTTTATTTTTTTTTAATTTGTCT CTTATGCTGAAATTTTATTTATGTCGTTGGTTTTTGGGGCTACTTCTTTCACTGCATTATTTGGCCTGGC TGGAATTTACTTGGTATAAGGAACAGGGTGGTATCCAGCTTCTGTTTCTTGGGTTTTTTCCCTGGCCTGG CTGTGGATGGAGCTTTTGGCTTCATTTCTCTGAGAGGAGGCCAGGAGTGGAGAGTGTCTTTGGTGCTCAA AGGTCCTGCCTAGTGGTGTCTCCAGAGAGGAAGGTGACAGAGACACCATCCCGGCTCTTCCTGCTCACCT GTCGGGCAGTTCCTTCTATTAGAAGGTTCCTGGCCTACTGGTCATTTACATCCCCCAGATTACCTCCTCA CCAGTGAAGTCTGAGGGTTTGGCAGAGTCTGGGCAGAAGGGTCAGGCTGGGGCCGGGACGGGGAGGGCTT TGTACTGACAGCCCACCCAGCCTCAGGGACACCCTCTCTGAAGGTGATGCCACCGGGGACCTCATCCACC ACGTGCTTAGGGGCTCAGAGAGACCGAAAACTGCAAGGAGTAGGTCCTTGGTCCACACTACAGGGAGCCA ATTCCAGCTTTCTCCAAAGCCATAGGGCTTTGCCTACGGTCACCTCTGGACCCACTGACCCAAACAAATG ACTACACCCGTAGGGCTGAAAACCAGGCCCACCCTATGGGGACCGGTGGTACCTTAAGGAAGTTCTTTAG CTTCCTTAAAAACAGCATGTAGGCTGGGCACAGTGGCTCATGCCTGTAATCCCAGCACTGTGGGAGGCCG CAGCGGGCAGATCACTTGAGGCCAGGAGTTCAGACCAGCCTGGCCAACATGGCGAAACTCCATCTCTACT AAAAATACAAAAATTAGCCAGGGATGGTTGCGCCCTCCTGTTGGAGGCTGAGGCACAAGAATCCCTTGAT CCCAGGAGGCGGAGGTTACAGTGAGCTGAGCTCGCACCACTGCACTCCAGCCTGGGTGATAGAGTGAGAC GCTGTTTAAAAAATAAAAGTAGGCCAGGCATGGTGGCTCATGCCTGTAATCTTAACACTTTGGGAAGCCG AGGCAGGCAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTGC TAAAAATACAAAAATTAGCCAGACATGATGGCGGGCGCCTGTAATCCTAGCTACTTGGGAGGCTGAGGCA GGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCGAGATCACACCATTGCACTCCAGCCTGG GTTACAGAGTGAGACCCTGTCTCAAAAAAATAAAAATAAATAATAAAAAAACTTAAAAAGAACAGCATAT ACCAGCCTCGGCAACATAGTAAGACTCTCAAAAAAAAAAATTAGCTGTGTGTGGTGGCACATGTCTTTAG GAGGCTGAGGCGGGAGGATTACCTGAGCCCAGGAGGTCCAGGCTGCAGTGAGCCATGATTGTGCCAGTGC ACTCCAGTCTGGGTGACAGAGCGAGACCCTGTCTCAAACAAACAAAACCCAATATGCCCAGTTCTTCAAG ATAGATATGAAGGGCAGCTAGACTCTTATAGTTGGATAGCGTGGCTAGAACAGTGGTCTTCAAAGTGAGT TCCCTGGACCAGTAACATCATCTGGAAACTTGTTCCAAATGCAAAAACTGGTTCCACTGTCTCAGAAACT CTTGGTGGTGGAGCCCAGCAATGTGTTTTAACAATCCCATCAGGTGATTCTGATATGCATTGCAGCGTGA AACCCAGTGTGTAAAAAGAAGCCACATACTCGAGACGAGCAGGTGTGATTGTTGAGGGACCCTGCAGGTT TCCTCACATGTCCGCCTGCCATTGGGTGTCTCTGCAGACTGCAGCAGCAGCTGCTATTAGCAAGAGCAGG CAGGTTGCACAATGTGGCTGGTGTCACAGCAGATCTGTGTCCCTCCTCACAATTTAACTGGCAGGGGACA TTGCCAAGGGATCCGTGTTCAGAGGGACTTCGTGAGAGCAGGTGTCTCACCTGGCACCTGTCCAGGCTGC TCTTCCTCCCTTACTGACAGATCTGCAAATCACTTACTTCTCTTAATCAGCAGCCTCTACTGCAGAAACA GGGTGATGCTGCCTCATTTGCCCTGGTTCTTCACCCTGCATCAGATGAACCTCCTGAGGGCCCTTTTTGC TTCTAGGAACGATGATTCCATACCTTACCAGGTCCCCTTGCCTGATGAACCAGAGGTTGGAGAATGAAGA GAGACAGGGGCCTCTGACTTCCCCTGTTGCTGGAGGGATGGCAATAAGGACACAGGAAGATAAATAGACA GACCTGGAGTCCTGAGAATGAGGCAGTGCGTCTCTACCTCTGAGGTGGGAGAACAGGCCCAGAGGCGCAC TGCACCCTTGCCAGCAGAGGCAGGAGCAAAGCTTCAGTGAGAGGGCCTTTCAAGGAAACTGGCTCATGGG GAGTGAATCCTGTCACTGTGGGTGGGGCCGGGGGTGTGGCCCTGGCCCAGAAGTCAGGCAGCATGCTGGT GGGTACTGTTTCTAGCTGGAGGCACCAGCAGGAGACAGTGAACTGGTCTGCGACAAGCAGGGCAGATGCA GCAGTTTCTTCTGCAGGGTCCCAGTTGTGGTGGTGGCTGCCCTTTCAAGAAGCTGGGTCCCACGGGCCAG CAGGGGCTCTCAGGCAGAGCCTGAATGTGCTTTCGTCTTCTCTTCCAGATCTAACCATGAGCTACCCTGG CTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTAAGAGGGTCTGGGGTGGGGAGGAGAGT GAATGCTGCCTCTGTACAGTGGCTGGGAGTGGAGAGGGGAGAACAGTAGTTTCCTCACTCCCCTCCTCCC CTCACAGCACGGCCCAGCAGGGGAGGAGAGGACAACAGGAGTAGTGGGACAGCCAGCCGAGGCAGGGGCT GGAGAAGAGCATGACACTAAGGCCATCGGAGGCCTAGGTTTGAAACTGCCTCCAGAAAGCCCTGGACCAG GCCCAGGGCTGGGTCTCTTGCCTTACTCTCTAGTAACAGTGGGCAAATGCTGTCACTTTGAGACTCAGTT TTCTTCTCCGCAAAATTGCTTCAAGGATTTCTCCCTCATTAGGTGGTCCTGGATACTGATGAGATAGGCA GGCAGAGCGACACGGTGTCCTCCAAAGCATTGCTAGGTGATGGTTGCCCCTTACCACCTCTCCTACCCTC TGCTCAAGGTGTGTGGGTTTGCAGCAACAAGATCCCCCTTGCCAAGAGAGGAAGTGGAGGCAGATGCTAA GGGTCAAAGGTCACTCCCTGTTTTCTGCAGGAGCTGTGGGTAGTCACATGGAGAAGTCGTCTTCTCTGGC CCTGGCCCCTTTTGGTCCTCAAATGAGATTTGGTCCCCACTGTGGGAAAGGAAATATGAGGGCTCATGAG ACCAAGGGGAGAAAAGGGTCATTCCAAGGCTGGTCATCCTGAGGGTGCCTGAGCCGCTGCCCCTCTCCCC AGGGGACTCCTAGGCATCATTGATTTCTTTGGAGCTGAGGTCCTGTGGTTTGAACACCCCAGACCTGCAG GCCATTTACCTTCCCTCCCATTCAGCAGGTGAAGAACAGACTCAGACCTAGAGGTGGCTCAGCTGCTGTC CCAGGGCATGTTAGGGGCTGAGCTGGGCCACTGCCCTCTGAATGAGCCCACCCCAGGTTGGCTGGCACTG GCCTGGGTTCTCTCTCTATAGTAGAAATCCTGCCATCCAGATCCTGCCACTGCCACCTTTGCTAGCACAG CTGAGCAGCCTCTGAGCAGCAAGAGAGGAGGAGGCAGGAAATTTAGGGAAGGTTCTTCCTGGAGGGTCTG GAGCCCTGGAGATGAAGAGCCGATCCGAAGCTGCCATGTAGAGGAAAGCATCTAACAGGCCAGAGGCCCC ATGATGATGTCGAATGCCCATCGGGCACCCAGCTGAGCCCTGCAGGTGTTAACTCAGTCTTCGTCACAGC AGTCTAGGCATACACTCACCATTAGCCCATTTGTAAGCTGAGGAAACAAGCCTAAGGAGGGTGAAAGCCT TGCCCCAGGGCACATACCGGTCCTGCTGGTTTCAGAGCGGGCTTTTCACCTCTGTTTCTTCCTGTCCTCT TGTGGACTGGTATCTGTGTTTACCATGACCCAGCCCCATGTCCCTCCAGCCTCTTATCCTGCTTCTCCCT GCCTTTTACAGACTTGTAATAGCAAACAGCCAAACCCCCTCCCGCCAGTGCCTTCGCATTACTGAAATCT CAGAGCTCCCTATGGTCACCTCTGTCATGGGCTCAGCATGGTGTCCCACAACAGTCTGTCCTTGTCTGTC CTCCTGCTCCATGATGGTGAACTTGGGAGGGCAGAGCCTGCCTGGGCTCTCCCAGCCTCCTTAATACCCC ACAGAGGGTCTTGGGAGTGTTTGGGGAACTCCACCTTCCTCCCTGGGAAGAGGGGAAGGTTTCCCCTCCT CTGCCAGTGGGATAGGGGGAGACTTTCCTCCTGGTGTTTTCATGTGGTCTGTGGTGTCCCGAGGCTCGAG GCTCGAGGCTTTACTGGGCCTCCCTTTCTGACCACCTGGGAGCTCTCATCTCTGCCTTTCCCCGTGTGGT GGGGGACTGGCAGGGGGCTAAAGGGCTTGGTGTTGCTTTCAGGTGGTGGTCCCTGGGGAGGTGCTGCCTA CCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTCAACCAG GACTATCTCTCGGGAATGGTGAGTCCAGCTCTCCTGCTGAGGCAGCCCTGGGGCCACACCTGCGTGGCCA GAGGAATCAAAGCTGCTGGCCTCTGGGGCTCCAGAGTTGTCTATGTGTGTGTTGCTGTGGTGTGTAGTGT GTTGAGCTGTACCTTAGAACAGGGTTTTCATCAGGCTTCTGCCACCTGCTCTCTGCCCCTCTCTGGGTCT CACTTTTCCCATCTGTAAAATGAGGGGAAGGGGACCAGATGATCTCACAGGTCCCTTTCAGCCCTGAGGG GTTAGGGTTGGGAAGGTGGCGAGGGTATCTGCATGAGTGTGCATGCACGTGCTATGTATGAGTATCCACA TTCATATACCTGCATGTGCATGTGTGTACATATGGAGGGCTCTTCTGGTTAGGCCTTGGTGGGTGTGTGG CAGGTATCTTGGGCAGACATGCTACTTTTTAAATTTGTTGTTTCACTTTTAAAATAATACATTTTATGAT TTGAAAACAAACGTATGCTTAGTTTATGATTTGAAAACAAACGTATGCTTAGAGGAAATTATGCAACCAA TACACACCCTAATTTGTGCCAGGCCCAGTTCTAGGCACTGGGGATATGTGAATAAAACAAACAAAAATCT CAGCCGTGCTGCACTTATCATCTATGGGGAAAAGACAGGCAGTACCTTAAGTCAACGATGTGATGTTATT GAAAGTGTAGGTGCCATAGGAACAAGTTGACCAGGGTAAAGGGGTCAGGAGTGGGGGTGGGGTGATGTAA GGATAATGATTTTAAGTTAGCAGTAAGGTGGGTCTGGCTGAAAAGAGGATGTGTGAGCAAAGACCTGCAT CAGGGGAAGGAAGTGCTGTATGGATGTCTAGGGAATGCCGGTGCCCTGAGGTGCCAAGGGGTGTGAGGTG CTCAGGGACAGGGAGGAGAGGCCAGTGTGGCTAAAGTGGAAAGGCGAGGGGGTGAGATGGGAAATGAAGT CTGGGGGTCTAGCTCTTGCAGGGTGTAGGAGGCTATCCATCCTAAGGATTTAGGTTTTTATTCCTGGTGA GTGCAGATTCACCTGAACATGCCTGCCAGAGGTGTCTGTGGGTAGCAGGCTGATGTGATGGGGATGCCCC CAACCCTGCATATGGGACCCACGCACCTTCTTGGGCAGTGAGCTCTTAACCTTCACCCAGGTGGTCTGGG ATGGGAGGAGCAACCATGTGGAGAGGGAAGGCATCTCCCCTGCAGAAGGGGATGAGGATCTCTGGTTTGG ATCGAGTCGCACTGTTCACTGGCTGTGTAACTTTGAGCAAGTAAACTCATTCTGTGGTCTGTGAAATGGG TATAACGGTACTTCATATTCCACAAGCGGAGATGCTGTGAGGACTGACTTGGCTTAGGTATGAAAAAGGG TGGAGGGACGGAGTGCAGCAGGGCCCATTGGCCTCAGGCTCTGCTTTGTGTCCTTGCAGGCGGCCAACAT GTCTGGGACATTTGGAGGAGCCAACATGCCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCA GTGCCCCCTGGCGGCTTTGGGCAGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCAC CCCCAGGAGGAAACCCACCCTCCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCA GCCCATGCCACCCCCCGGACAGCAGCCCCCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGT CAGCCTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGGGGTCTGGGA CTGTCACCCCCGCTGTGCCCCCAACCCAGGTGAGTGTCAGCCCACTGCCTCCCTTGGTCCAGGCCTGGGC CCCAAAGGCTGGAGACACATGGCTCAGTAGATGGGGAGACAGGGAAAGGCGCAGGCCTCCAGCTGCACTT CTTGTTTTAACAAATAGTGTCGGCCGGGTGCAGTGACTCATGCCTGTAATCCCAGCACTTTGGGAAGCTG AGGTGGGCAGATCGCTTGAGCCCAGGAGTTCAAGACCAACCTGGGCGAAATGGTGAAACCCTATCTCTAC TAAAAATAGAAAAAAAATTAGCTGGGCATGGTGGTGCATACCTGTAGGCCCAGCTACTCGGGAGGCTGAG GTGGGAGGATCACCTCAGCCCAGGAGACAGAGGTTGCAGTGAGCCGGGATCATGCCGCTGCACTCACTCC AGCCTAGGTGACAGAGTAAGACCCAGTTTTTAAAACAAAAACAAAAACAAAAAAAGACAAACAAAGAGCG TCACCTTCTTGCAGACTCCCCACCTCTGGGTTGTGTTGCTTAAGGCCCAAGGGAGCTGTCCTGTTTCTCC TGGTGTGATGAGACGCTCCACATCCGAGTTGGGTCAGAACACCCCTGGCGAGTACTCCTTATTCCTCTGT GTCATTTACTGCCTGGGCTGTGTGTTTTGTAAGAACTGCCCAGGCCACCTGTCTCAAGGCTTTGTGCTCA ACAGCTGTCTTCGGTCCCTTGATATGCACCACCCCCGCCCCCCCCGGCACAGACAGGTTTTGGAGGATTA TTAAAATTCCCTTTGGGTAGGGAGAATGTTGGCAGTTCCTCCAGGGTTGATCTTGGCTCATTTTGGAGAA CAGTTCGTGTTTGCAGAGCCTAGAATTCGTTGTCATGGTTCTGTGGCCCAACCAGCCAGCACAGGGGTAG TGGTATGTGCTCAATGACTATTTTTAGACAGAGGGTCTCCTTTCCTCCTTCCCTTCCATACCCACACGTT CCCCCACCCTGTGCCATCCTCCAGCCTCCCTCCCTTATCTTTTCCCTGAGCTGCCCTCTTAATTGTGTTA TAACCAGTTTGTACCAGCCCCTAGGAAGACAATCCACTGGGAGACAGTTTAGCCTGGAAAGTTCCAGTTT GCGGGTTTGTGCAGCTATCAGGGTCTGGAGGAAGTCCGGCAGATGCTAGTCTAGAGAACAGTGCGAGGGA ACCAGTGCTAGATCAAGAGGTCATCAGGCTGCCATGCACAGTTGTGGAGGCTCAATACCTGCATCCACTG GAGGGGACACATGGGCTAGCCAGCCCTGTTAGGAGTACCCATGTGTGCTCACATGTGCTGTGGAGGCCAG GCATCGATGAGAGAGGCCACAGCCCCTGCTCCCGAGACCTGCCCTTCATCAGGAGCCTGAGCCCCAGCCC TGGAGGACCTGGGCACTGGGCAGATTTTCAGCATCAGGACTCAGCTATAGGTGAGCTCCCAGCCACTGGA GCCAGGAAAAAGCTTCAGTACTAGAACACAAGGCCAGATAACAGTCAAGTTAGGTAGACGCGGCGTAAAG TCCTCTGCATTGTTGACTGTGGACTCCTTTAGATACTCCAACTCTTAGAGAAAGGGCTGTTCCCAGAGTC TAGGGGTGGAGCAGCCTTGAATGTGGGGAAGGCGGCATGCACGACATCTTACCTGAGACTGTTTGTCCGA GTAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAGATGCCGAGGTCCTG CGGAAGGCCATGAAAGGCTTCGGTAAGAGACCCTGGGTGGCTCAAATCCTACTCCCTGCCCCCTATTTCC CAGGCAGTTTCACTGTGGCTCTGTGGGCTGGGGTAGCTGGGGGACGCTGACCTGGCCCCAGTGGTGATAG AAGGTGGATGTGGGGGTATGGCTAGCATGCCCAGAACAGTTGAGGGGCCCAGGCCAGGGAAGTCTCAGCT GCAGAGCATCTCATGACCCCTACCCGACCCACCCCTGCTGCCTCTTCCTCCAGGGACGGATGAGCAGGCC ATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGCGGCAGCAGATCCTACTTTCCTTCAAGACGGCTT ACGGCAAGGCGAGCTGCGGGGTGGGGGCGCGGGACAGTGAGGCGTGTCCTGGGCTCAGCACAGCCCTGCT CTCCCCTGCTTTTCCTTGGGTGGGCCCGGATCTCCCGGATGGACAGTAAGGAGCAGGAGGGCATTTCCTT CTGCCCATCCAGCTGGTGGCATCGTTGGGAGGTGAAGGATGCCACCGGGTGCTGAGGTTTGCTGAGAGGC TCCAGACATCTATCCCTGGGTTCTAGCCCTTGCTCTGCCACATCTCACTGAGGTTGTGGCCACATCATTT TCCTTCCCCTGCCCTCTTCATGACCACCCTGGGGGGTTTAGCTGATGTAAGAGCTTTGCAGGGAAAGGCT GTGAGTGCTGCCCAAGTACGAGGGGCGTGTATGAGCATATTTTGAACTTCTGGGGTTTTGAATCTTAGAA AGATAAAAATTCGGTAAATATTGATTAGATTCGTGTTCTAGCCCAGTGCTTCTCAAACTTCATTGTGTCA CCGATCCCCTGGGCATCTTGGTAAAATGTGGTCTCTGATTTGGGAGGTTTGGGGCAGGGCTGAGAGCAGG CTTTTCTCTCAGGCCCCTGGGGGATGTCCATGCTGCTGTTCCTCAAATCTGGGATATGGCTCTTATTAGT CACTTCCTGTGGATTTTTTAAATAGACTTGTTTTTTTTTTTGTTGGTTGTTTGTTTGAATATCCAATCAG GATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTTGAGAAGACAATCTTGGCTCTGATGAAGA CCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAGCCATCAAGGTGTGTACGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGCGCGCGTGTGTGCGCACGCGCGCATGCGTGTGGACACACAGCCCAGAAGGAGGCC TGGATGGCGTGCTGTGTTCTAGCCCACTCATTAGCTGCTGTTGTCAGTATGGCTCCCAGGCCTTCCTGGG TTGGAGTCCACATGCTATAGAAAAGGGAACTCCCTGTGATTTCCCCAAGAGGCAAATGACGCACCAGTCA TCATCAGGGAGGCTTAAGTCTCTCTCCATCTTAAAGAAAAGGGGGAGCTCGGGTTTGAAGGTTGCGATTC TGTGGTAAGAAGAGGGGTAGGAGGCCATGGTTGGTATCGTTCTCATTCTTTAGGACTCTGTTACTAGCAA ATGACAGAAACACACTTCGGTTTAAGAACAACAAAAGTGGAGAATCAGTCATGTGGGTAAAGAGGGCCCA GGCCAGACGTCTCTCTGGTCTCTGTCTCTCCTGAGCGCCCGCTTTTCTGTCAGTTTCTGTGCTTCTCCTA CCATGGCTGCTTCATGTGGGGTGGGAGAGGGGGCCTGTCGACCACTCTCCGCATAACTATGAGACCCAGC TCCAGAAGAGACCAGCAGGGTCTCCAAACGGGCAGGTTCTGACGGGCCCGGCTTGGACTCACTGTTCCCT CCAGTCCTGCGGGTTTTGACTGAGGGTTGGGTCCTGTCCATTCTGTGCAGTCCCACAGCTCTGTGTGCAC CCTGCAGGCAGGGGCAGGCAGCTCCCTTGGAAAGGGAATCCCATGAGTCAGGCTGGAGCCCAGAAGGAGC CTGTCACTCAGAGGCCTGATAAGCACAGTGAATGTTCCCTCCTTCAGGAGAAGCAGAGACTTCAGTGTGG TGGCCTGGAAAGGAGAGGGGTCTCCGCTGAAACACATCTACATGTGTTATTCTAGGGAGGGGGTCAGGAG GCCATCAGGCAGGGCGATGGCCCGGGGCCCCAGGGAGTGGACCCAGACATCTCCCTGGCCCCCGTCTTCA GCCGGAGTCATGAGCTGGTGGTTGTGGAGTGTTAGAAACCACACAGGTTTGGGGCAGCTGTCACTCACCA GCTGTGTGTCCTTGAGCACCTGTGAAATGGGGACAGTGGATGCTGTCTCAGGACATGCTGGGAATACTGG GTGAGGGGCTAACGTGTAGTAACCCAATAGTAGCTGTAGCAGGAAACAGCTGACACAATGTCGCACGTCC TGCCTGACAGGCCCTAAGTGCTCTACGTACATTAACTCACTTAATCCTCATGACTTTCCTGTGAGGTAGG TCCTAGTATCACTCCCATCTTACAGACAAGGAACTGGAAGCACAGAGAGGTTAAGTAATGTGCCCGAGGT CACACAGCTGGTAAGCTGCAGAGCCAGGATTCAAACCAACATACAAGCCAGGCTGCCCAGCCTGTCCTCT ATGGTCTTACTGTCCCTGGCGTGGTTGTCCGATTCATCCTTGTTGTTCCTACCTTTTCCTAGTTGTTTTC AGACATTCCACCATCCCCTCTAGGACCAGGGTTTCGTATGTCCACTTGGATCTCTCTTGCTTTTTACCCA TTTTTTTCAGTTGTTGTCATCTCGCTTCCGGCTGAACTCTGAATAAAGCAGGCCTCGGTCCACATTTTAA CCCAACCATTTACTGTGTGGCCTCGGACCAGCCAGTACCCCTCTCTGATGCTCAGTTTTCTGATCCATGG GGATGCCCCTTTGTGTGAGCCCTACTCATCACCACTGCCACTGTCATTGTGCTTGCCCGGGCTGTGGAGA AGAGCTGATGCCCTCGAGCCTGGGAGTGGCTGGAGGGTGTGTCTCTGTGTCAGGGGCCTCTGTTGCTGGG ATTAAGGCAGCAGCGTAGCCCCCACCCTTCTTCCCGAGTGCTGGTGAGGCTGCTGGAACAAGCACATGGT TGGTTGTATTCTCTGCCCCTGCAGGGGGTTGGCACTGATGAAGCCTGCCTGATTGAGATCCTCGCTTCCC GCAGCAATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGGTGAGGCCGCTCCCTCTGCCCTCTG CCCTCTGCCCTCTGCAGATCCCTGTGCTCTTGGGGCTGTGGCCTCATTCTCTCCTAGGGCCTTTTACTCC TTCCTGGCCTTCTTATCAACCCATCTTCTGCCACCCCCAATACTTTGGGCTTTGACCCAAGACCCAGCCC TTCCTTCTGTTTATACATGGTGCAAATGACTAATGTAAGGGAGAGGCAGGGAAAACCTGGATGTGGTTTG GGCCAAGGCTGACTAGAGGCCAGGTCAGCCTGGAGGTCACAGGCTTGTATATCCCTGGAGGGCCATATGG GCTATTTGTTCTCTTGAGCCCGAGCCAAGACCTCCAGCCTTTTTCTCCCCAGTACCCACTTTTGATAGTG TTTTGCAATGGGCAGCTCCATAAAGAGAGCTACAGGATGGACCTTCCTTGCTTCTCCCTTTCAGAATTCA AAAAGACCCTGGAAGAGGCCATTCGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTC TCAGGTACTTTTCCCACGACAGGGCTCGGGGCCCCCAAGCCATGGAAGTCAAAGAGATGGGATCCCCGCA ATGAGGAAAGGGAAAATAAATGGGGAAGGAGTGGGCATGACCATACACCTGCTTCCTTTCAGGGAAACCG TGATGAAAGCACAAACGTGGACATGTCACTCGCCCAGAGAGATGCCCAGGTGAGTGTGATGGCCAAGCCC CTGGACTTCCTAAAGCAGGGATGCACCCCGCTTTCTTGCTTCCTGAGAGAGGTACCCTAGGGTGGAAAGA ACAATAGATAAGCAGTGGGTTGCAGATGCTGTGAGTTTCAGACGCGCTGAACTGTTCAACTGTATGACCT AGAACAGGTAATCTGACCTCCAGGGCTTCAGCTTCCCCACCTATAGGAGGGAACATGTGAGATAATTAGT ATTTCGATAGTTGATAGATCATGGTTTTGGACGTGGGATTTTGTGTGACAGCGTACTTTCCCCATGTTTA GTTGCACATAGCATTATGTTTGCAAAGGGGCAAAATTTGCACTTGCTTATTAAGTTTTTGAGGATTTGAG CCTAGAAACCAGCTGCCACATTAGTTGAGCACCCTTAGAATTCTGTCGTTGTCCCTCTTGTGAGTTGCAG ACAAAAGGGGAAAAGTCCAAGCAAAGTCCAGGCATCTGAGCTACTCTCTCGAAAAGTTTGGGTTTCCCAC TAATGAATTTCAACCGTAGTATTATGGCAGGGCAGAGCCATTACTTCCTGGTGGGGTGGAGTTGGCCATA CCTCTCTGTCTCCCTTCACTGCTCTTGTCATCCACGGCAGGGCATTCACCAGGAGCTGCCAGTGGTCTAA ATTATCTCTACCATCTGCGGGATTGGAATGAGACCTCAAGGAATGCCCCCTTGTTAGGGCTGGAGGAGAG CTACTCCTCTGGTCTGGTCCTTTTGCTGGTCCTCCTTTTCCGGAGGAGGAAACTGAGGCTCAAAAAGGTT GAGCACTGTTCCCAACTGAAAGCTAGAAGCAGAGCCCGGACAAGGGCCTATACTCCTGGCTCGGTCTTCT GTGCCCAGTCAGCACTTGCCTCTGCCCTGGTCTCAGACCTGCTGCTCCTGCAGGGTCTGCCTTATTCAGT GTCTCTCTGGCTGGTAACATCCATTCCCATTCTGGGAGTCAGGGCTGGACACGCCTGGGGCTCAGGGCTC TGGCTTTTGCTCCAGCGAGAGTTTTGCATGCCACTTTTAGCGGGGCAAAAATTGTCTCATGCTCTGCCTT CTCAGTCCAGAGCTGCTTTGGCCTCATCTTGACCTGTGGGATCTCAGCCCCTGATTGCTGCTTTCTGCTC TTTTTCAGGGCTGCTACCTGAGGCCTAGCAGGCACTTTAGAGGCCATCTAGTTCAGAGGTTGCAAATTGG CAAATACTTTAGGCTCAAACCTTCAGAAGTTTACCAGGCTCTCCTGGGTGACCTGGGCCTGGGGTCTGGG TGTGGCCTGTGCCACATGTGCGTCTTCCTCTCTCTCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGG GAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCTCCCGGAGCCGGGCCCACCTGGTAGCAGGTAAGGC AGGCTGGGGTCCCTCAGAGGCCAGTTAGATGAGGGCAGTCAGGGGATTGTGGGGAAACAAAGCTATGGGA ACACTTGGTCGTTCCTCCCTGCGTGGGGCTTTCGCCTCCTCAAAAGAGCCCCCTGGTGGGAATTTAAAAG ACACTGTCAGAGGGTTTCCTGAGTTCTGGCAAACATCCAGTTCTGGAGGTTCTACCGGTGTAGAAACCTG GTGTCTTTGTACGTGGGAATGTGGAACGTCAGAGTTGGGAGGGTCCTTCGGGAGCACCCAATCCAGTGTT TTCCAAAGCCTGGCATAAGAAACAGTCATAACAATAAAACTGGGTGCCATTCATTTACTCATTCATTCAA CAGATGTAAATCGCGCTCCCGCATGGGTCAGTCTGTCAGGTGGTGGAGCAGGTGTGGGGCCACGGTGGGG GGCAGGGCACTGCAGAGTGTGTTCCATGGGCTGCACTTTCTCATTTGGGGAGACAGACAGTAAACAACAA TGAAATAAAATCTGTATCAGATGGGAAATCCTGTAGAGGAAAATCAAGCTGGAAACAGGTAGGGAGTGAT GGTAGGGTCCACCGGGAGGTGCTTGGGCCAGTCCCCACTGAGGTCGTGACATTTGATTTAAAAACCTAAA GGGAGATGCAGGGGCAGAGGCCTGCCTGGGGCTCCCAGCACGACTGAGAACAGTGAAGGGGGACCATGTG GAGCAGGTGGAGTGAGCAAGAGGAGTGGGAGGTGAGGGCAGAGAGGGGAGAGGGCCCTGCTGATGACTTC CCGGAGCTGGGTATTTATCCTGAGCAAAAGAGGAAGCCAGTGGAGGGCCCTGAGCAGAGGAGGCTGTGCA GAATCCCTGGCTGTGGTGCCGAGAATGGAGTGAAGGGTGCAAGGCCAAGCAGCGAAGCCTGTCGGGAGGC TGCTGCAGGGACCCGGGGAGGAATGGTGGTAATAGGGGCTTGTGGTGAGGAGGTGTCAGGTTCCGGCCAT GTTTGCTGATGAATTGGACACGTGACGTGTGGGAGAGAGAGGGTTCGAGGATTATACAGGGTTTCTTTAG GCCAAGCAGTGGGAGAATGGCCCTCAACTGAGACAGGGGGACTGTAGGTGGAGCTGGCTTTAGGTGCCTG TAGGGTGGAGCTGCAGGGAGGCTGCTGGGTTGCTGAGTGTGGAGGTCAGGAGAGGTCTGGCCTGGTTGTG GAAGGTAAGGGAGCTATGGGTAGTTGAAGTTATCTGAGGCTCTGGGACTGCAGGAGGTCCCCTCAGGAGG GAGACTGTGGGGAGCCCACCGGTGTGAGGAGACTAAGAAGGAGCAGCTAGGGAGGGAGGAGGACGCAGAG GAAGGGGGTCCTGGAGGCCAGTGTGAGGTGGCAGGCAAGGACTGAGGATGGTGACCACACGGAGCAACTG GTGGGCTGTGGCCAGGGCTGCTCCAGTGGGCAGTGAGGGTGAAAACCCAGCGACCGCTCTGTGCTGCACA CAGAGACAGGCGCTGTGGCTCTCCCCATTCGCAGCTGTGAAAGCAGGCACAGGGTGGTAGAGGAAGTAGG GGTGCACAGCTAGTAACAGCTGAGCTGGGATTTGAACCCAGACCACCCGACCCCAGAGCACACTTTTTAA CCTCTGCACTATCCTGTAATGGAGCCTGAGTGAAAGCATTTTCATCTTAATCATTATTTCTTTTAATGAG TACAGAACATGTAAGTAGTGCATCAAGCCCATGGCTTCACAAACATTATTACTTAGGAGAAAAGAGTAGC TGATTGGAAGAAGATATTAATTGAGACAGATACACACAGAGCAGAAATCACAACTTTAAAATGCAAATGG TAGCTGAGACTCAGGCTGGGGAAGGAGAGTTTTATGTCCTGGGTCAGAACTGGAGTCAGGACCAAGGTCT CCATCATGCCACCTGTCTCTCTAGGAGCCAGCCATCCACTCCTGTGGGTGCTTAGCGTGTCCTAGGTCGA GGTGAGCAGCAAGAAGCCAGGCTGGCTGGGGCAGGCTGGGCCTCAGCTCACAGGCAGGCTGAGGAAGACA GATGGATGCATGAATAAAGCCAAGGAATGGCAGAGACTGGAGGTGTGGAGGATTTGAGAAGAGGGGACAC TGTCTTGGAGTACATGGGAGTGGGCCCTGGAGGGGTATTAAGGTGCGATTTGGTTAAGCAGATTGGCAGT CCTGAGAAAGGGACCACACAGGGAGGGACATCAGGTGGTGCATGTAACTTGTGACGAAGACTCTGACTTC CTTGAGCGCTAGCAGGCCTGGGGACGTGCAGGGTGTGGGAGCAGAGTGGCAGGTGGGAGATTTTGGGGCA GAGGCCACCTCATGTGAGTCCTCTGTTAGTCTGCTCATGCTGCCATGACAAAATACCACAGACTGGGTGG CTTAAGCAGCAGATACTCATTTTGTTACAGTTTTGAAGGCCAGATATCCAAGAGTGGGGTGCCGGTTTCT CCCGTGGCCTCTTCGTGACAATCACTGTGCTCACATGGTCTTTCCTCTGCATGTGCACATCCCTGGGATC TCTGTGTGTGTCCTAATCTTCTCTTCTTCTAAGGAGACCAGGCGAATTGGATTAGGGTACACCCTAGCAG CATGTTTTAACTTAATTACCTCTTTAAAGATCTTATCTCCAAACACGGTTATATTCTGAAGTCCTGGGAG TTGGGACTTCCACATATGAACTTTGGGGAGACACATTTCAGTTCATAATATAAGCCTCTGTCATCCCCAT AGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGTCCGGG GACCTGGAGGAGGGCATGCTGGCCGTGGGTAAGTGTCTCAGGTTTGCCGCCCACCTGCCAGGGGCTAACG TGTATCGTGAGTGTTCAGGCTGCTCGCCTGTCCTCCAGCTGATGGGTGACACCGTGAAGGGACCACAGGA TCCAAGATCGCTCAGCCCAGAGTGTCCAGATGCTGGGAAGTCATGCTGCTTCCCGGTTCCCTGTGCAGTT GAACCCCTAGCTGTCCTGGAGGTGTCTTGTGTGTGTTTGCGGTGCAGCTCTGGAGTAGGGAACTGCAGTG TGGGTATTAGTGGGAGGGCATCCAACTGCGCTCCCGGAGGAGTATGACTCATATCCTGCCACGTTTCCTC TAAAAATACATCCCTGCAGGCAGTTGTCAGATGTTTGTGATGGAAACACGTGGAAAGATTTTTACTTGCA GCAGCGAAACAGGCCCATGCTGAGGAAAGCTGGCTTGGCTCCAGGATGGTGGTGTGCCTCTTACATTGCC CATGTCCTCTAGCAGGGCCCTCCCACTGTGCAGAGTTGGGTCCCTGCCCTGAGGCCCTCACAACCCCTCT TTCTACTCACTTGGGAAAATCAGTCTGCCCCTTTTTTCATTATGCTTTTTTTGGAGCTTTCTGGATGGGA GAGATGGAAAATCCTCATTTCCCTGCCTGTCCCCCATAGTAGGTCTCATGGCCTGGGAAGCCTAGGGAGA TGCACATTCCACTCAGCCACGGTTTCTCCATGACGGTCATGGCCTCTCCAGTCTGCCCCTCCTGCCTGAG CAGCAGCACAGTTCCTCATCACCATCCACATTGCTTCCCTGTGTAGCTCCTAGCCCCACTAAGACCCCCG CCCCTCTGACTCTTGGTCCTTTCACCGCAGTGGTTGCCAGGAAAGAGGGTGGGTTGGTTTCCAGGCTTTG CGTGTTTCTGTTCCAAATAGCTGGAGCCAAGATCATGGGATAGTTGAGCCTGGAACAGAAGGAGGAGGAG AAAAGATGGATGCAGTGATGGGTTTGACATCTGGGCCTCTAAGAGGACACTTGTAGACTCCATGCCCTGC TTGGGCTGAGAATTTTCTGCAGATCTGGTTATGCCGAGTTTCTCTCTTCTAGTGAAATGTCTCAAGAATA CCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGAGGGTATGTAACTTCCATGTGCAGGTTGCGAT GGAACCTTAGCCTCGCCTGTGCCTGGGACCAAGGGCTGAGGGCAGAAGGCCTGGGGAGAGCTAAATCTCA GCTGAGAGTTCCGAGGACCTGGGTAGGGAGGGGACTGGAGGGCCCAGGGCAGGTGGGAAGGTGAGGAGGC CTGGTGCTCATGCTCTTGGGTGGACTCTCTTTAGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATC ATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGCGGATGTACGGCAAGTCGC TGTACCACGACATCTCGGTACGGGCCTGCTGCAGGCCAACTGGGCTCCCTTTTGGCATCTCAGTCACCTG TGGAACCTCCCTCCTTGGAGTGGCCATATGCTTGGCCTCTGTGCTGTGTGTGGGCATCTTGATTATGGAC CTCGGACTTGTTCATCCCCTTGCCCTTAAACAGATTATAAATTTCTGAGGGCAGGTGGATCATGACCTTG CTGTCGCCCCCACCTTGCATCCCCCAGCAGCATCAGAGAACACTCGGGACCTCCCCAACCTTGACCGTGA CCTTCAGCGTTCCGATCACCGTGTGATTCCTTGATCTGTCAGTGAGAACTCATGTCCCAAAGGCTCTGTG GAGCTCTGCTGTCACTCCCTGACAAAGCACTTCCTGCACTCAGCTTTATGGCGTAGGCCACATAGTAAGG CCGTTCAGAGCGAGGGCCCTGGGGGTCACGCCACTTGGAGTCCAGCTTTTCTACTTGCTAACTGTGTGAC CTTGAATGGCTCCCTTAAATCTCCCTGAACCCCAGCTCCATTGTCTTTAAGATGAGAAAATAATCGTTCC TTCCTGGGAATGTTGTGAGTATTGAGTGAGGCAGTGCAGGTCAAGTGTCTATTAAACACTAGCCACAGTT GTATCGCTGTGTGGCAGAGCCAGTCTGACAAAATACATTCTCAGCTGTGTGGTCTAACGCTCAAATTCTG AACTCACATGAGCCTTGCAATTGCACCATGGGGACCACGTCCTCCCACCTTAGACTCAGTAGCATTTGAT GATGGTGGGCATGTCATCACAGGAAACTCACTGTGTTTCCTTGGCTGTATGAATGAAGCTGTTGTTAGAG AATTAGTGATTCTAGGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGG TGGATCATTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAAGGTAAAACCCTGTCTCTACTAAAAAT ACAAAATTAGCTGGGCTTGCCTGTAATCCCAGCTAATTAGGTAGGCTGCGGCAGGAGAATTGCTTGAACC CGGGAGACAGAGGTTGCAGTGAGCTGGGATCACGCCATTCCACTTCAGTCTTGGTGACAGAGTGAGACTT CGTCTCAAAAAAAAAAAGAGAGTTAATAATTCATTACAGAGTATCTCCTGCATGCCAGCAAGCTATGGAC ATCTGGAAGAAGCCACATGCCTTGCCCTCAAGTTGCTTAGGGTGGAAGGAAATGATTAGAAATGAGCCAA GCCGAGCCTGCACTCTTAGAGTAAGTGTAGTGGCCTCAGACAGAGGAGAGATCCCTGGGACCTGGGCAGT CTGAGCCTTCCACTGGACAGTCATGTGTGAGGAGATTGCATTTCCTGAGCAGGACACTGTGTTGCGTTAC ATTGGTAACCCCAATTTAAGGCAGCATAAATGCACTGGGAAAACAGCAATATTGGTTAGCCCTGGGAAGT GGTTTTTAGGATGATTATAATTTTTTTTTGTGGGTATTCATTTGATGTGGATAGCTGGGGTGAGTGCTGC TTTCCGTCTTCTGATGGGGGCCTGGAGAAGGCTGAACTGCATTTTTTAAGGTCTGTGACGCCTGCTGCAG GACCTGCAGTGGGAGAAAATTCCCCAGGGTGGGGCTTTCTCCCTATAAGGGTGCTCAGGGCTGAATATCA GGACCCAGAAGGCTGAAAGTGACTGTCCCTCCCTTAACGGATGTCTTCCTTGTTTCTGTGGCCAGGGAGA TACTTCAGGGGATTACCGGAAGATTCTGCTGAAGATCTGTGGTGGCAATGACTGAACAGTGACTGGTGGC TCACTTCTGCCCACCTGCCGGCAACACCAGTGCCAGGAAAAGGCCAAAAGAATGTCTGTTTCTAACAAAT CCACAAATAGCCCCGAGATTCACCGTCCTAGAGCTTAGGCCTGTCTTCCACCCCTCCTGACCCGTATAGT GTGCCACAGGACCTGGGTCGGTCTAGAACTCTCTCAGGATGCCTTTTCTACCCCATCCCTCACAGCCTCT TGCTGCTAAAATAGATGTTTCATTTTTCTGACTCATGCAATCATTCCCCTTTGCCTGTGGCTAAGACTTG GCTTCATTTCGTCATGTAATTGTATATTTTTATTTGGAGGCATATTTTCTTTTCTTACAGTCATTGCCAG ACAGAGGCATACAAGTCTGTTTGCTGCATACACATTTCTGGTGAGGGCGACTGGGTGGGTGAAGCACCGT GTCCTCGCTGAGGAGAGAAAGGGAGGCGTGCCTGAGAAGGTAGCCTGTGCATCTGGTGAGTGTGTCACGA GCTTTGTTACTGCCAAACTCACTCCTTTTTAGAAAAAACAAAAAAAAAGGGCCAGAAAGTCATTCCTTCC ATCTTCCTTGCAGAAACCACGAGAACAAAGCCAGTTCCCTGTCAGTGACAGGGCTTCTTGTAATTTGTGG TATGTGCCTTAAACCTGAATGTCTGTAGCCAAAACTTGTTTCCACATTAAGAGTCAGCCAGCTCTGGAAT GGTCTGGAAATGTCTTCCTGGTACCAACTTGTTTTCTTCTGCTTGATTCTGCCCTGTGGCTCAGAGGTCT GGCCTTATCAGCCAGTGAAAGTTCATGTAACCTTACGTAGAGATTTGTGTGCAGGAAACCCTGAGCATAC ACTAGTTTGCAGGGACTCGTAAGGACATGGGAAGGGAGGTTCCCGAAATCCAGGCAGGAGGCCCAGACAC CTGAAAGGCAAAGGGATCTTGGTTGGTTGCAGGTGCAGTGAAGTCCACTGAAGGTGTGGTGCGAAGAATG CAGTCCTTCACCCAGGTCCCAGGAGGGAAGAAGGGTGTGTGCTAATTCCTGGTGCCCCTCGGCGGGGGCC AGAGAGAAGGATGGGGACAACCCAGAGAGTCACAAGACCAGTGCCTCCCCTCAGGGTGCCTCCAGGCTGA AAGGGGCTCCTGGCTCTGGTCTCTGGGGACCCTGTGCCCGTTGGTTGGTGGTGTGAGGGAAGAGAATCCA TAAGAGAGTTTCTGAGAATTATGGTGTCATGTCCAGAAGCTAGAGCTTACCTTGCATCAGGGGTCTCCAC CCACTCCTTTTCCAACCTCCTGCGTTGAGGTTTAGAAAAGAGAGAATCGACTAGGCACTATGGCTCACGC CTGTAATCCAAGGACTTTGGGAAGCTGAGGTGAGAGGATCACTTGAGCTCAGGAGTTCAAGACTAGCCTA GCCAACAGCGAGACCCCTGTCTCTACTAAAAAATTTGGCCAGGCGTGGTGGCTCACGGCTGTAATCCCAG CACTTTGGGAGGTGAGGCGGGCAGATCACCTGAGGTCAGGAGTTCGAGACCCAGCCTGGCCAACATGGTG AAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCACATTCCTGTAATCCCAGCTACA CAGGATGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGTAGTGAGCTGAGATCACACCAT TGCACTTCAACCTGGGTGGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAATTTACCTGGCATTGTA GTGCATTCCCTATAGTCGGCTACTCTGGAGGCTGAGGCAGGAAGATCCTTAGAGCCCAAGAAATTGAGGC CGTAGTAAGCTGTGATTACACCACTGCACTCCAGCCTGGACAACAGAGCGAGACCTTGTCTCAAATGAGA AAAAAACAAAAAGAAATGGGAGAATCCAGAGAGACTAGGCTAGATCAAGCCTGCTGGGTCCTGGCAGGAG CCCCAGGGAGTAGCTCATCTGCAGACATTTGCTTGAGGACTACCCCCTAAACATAAAGGAAGAATGACAT CCGAAGGGTGTGGAGCAGCCATGAGCTGAGAACTAGCCTGGTCTACCTGAGATTGATGGCAGGTCCTGGT CAACACGTCAGCTCTGCGTCAGAGTCCATGCCTCAAGCCCAAGCTGAAGCCCCATCCCTGCTGCTCTCCC AAGAACTCCTCTGCTAGGGCAGGCCCCTTGCCCTTGGGTGCCAGGTGGGACCTGCCTGATGGGATGGGGT GCTTGGCATATACAACTTGCCATGAACTCAAGGTGACCCTGGGGGCCTCCTGAATTGTGATGGGGCCTAG AACCAATGTGCTCTGATGTGACCATATTCTGTGACATTACCTTGCCCTGTTTACTCCAAAGTTCCCAGCC TGGTGCCCAGCAGGCAATATTGCACCTACAGACACATTTACTTTGGTTTCCAAAGTGTTTTTAGACATTT GAATTTGTTGCCAACATTTAAACATTGAGAGATTTCATATTTTTAAAAATCTGGAATTCTGGCTTCTCTT GAAAACTCAGAAATTCTGGCACTATGGGGCTTGCATTCCTGCATGGCTGGAGCTGAGTTGCAGCTGCCCC TTTAGGCCTGTACTCCTTATTTGCTATAGGCTCCGTCTTGTATTACACTAAGCCCATGTCACCCATTTGG CTCCTGCAGGCCTTTGGGTTTGAGACCCTGGTCTACACACTTGGAGACCACCTGTTGTAAAGTACATGGA TGTGCTTTGGTCAAGGAATAGACCAAGGTGGATATCCAGGCCAGAGTGACTCAGCGAGTTTAGGTCACAG GCGTATACTCCACTTGTTATATAACCTGCTTGTGTAAGTTCATACTTGGCTCAAAGCCACTATTGTTTGG AAAAGGTATAACTGCCCTGCTGACGCTGTACAGATGTTCTTGGGCTCGGATGGGCATGGCTCCACGTGGT GTGCACTAGCACCCAGAGAGAGTGAAGCTATTGACCCCTGTAAGGGAGAGTGACCATCTGGCAGATAGAT AGAGGGGAGCCAGGACATGGCTCAGCTTGTGCCCAGAGGGAGAGTTAAGCCGCTGACCCTGTAGCCAGGG AGTGCACCTGCAAGCATGGGGGTGGCAGGAGCCACAGAGCTGGCTGCTGAGAGGAGCTGCAGATCTGGAG AAGACAGCCTAGGTAAAGGTGGACAGTGTGAGAGCTGCTGATGAGATAGCTGCTGAATAAAACTACATTT TACCTGCC Download Select all
Length	53068
OMIM ID	602572
HGNC ID	HGNC:535
Unigene ID	Hs.530291
Ensembl ID	ENSG00000122359
PharmGKB ID	-

mRNA Information

mRNA ID	XM_011539736.1
Exon	join(142..335,24223..24737,29523..29571,32809..32871, 34763..34878,36320..36709,38365..38452,38694..38788, 39481..39594,41535..41625,42065..42144,42273..42329, 43650..43743,46483..46578,47653..47711,47915..48037, 49766..53068)
mRNA Sequence	>311 GCACTGCCTCTGGCACCTGGGGCAGCCGCGCCCGCGGAGTTTTCCGCCCGGCGCTGACGGCTGC TGCGCCCGCGGCTCCCCAGTGCCCCGAGTGCCCCGCGGGCCCCGCGAGCGGGAGTGGGACCCAG CCCCTAGGCAGAACCCAGGCGCCGCGCCCGGGACGCCCGCGGAGAGAGCCACTCCCGCCCACGT CCCATTTCGCCCCTCGCGTCCGGAGTCCCCGTGGCCAGATCTAACCATGAGCTACCCTGGCTAT CCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTGGTGGTCCCTGGGGAGGTGCTGCCT ACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTT CAACCAGGACTATCTCTCGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATG CCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAGTGCCCCCTGGCGGCTTTGGGC AGCCCCCCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCC ACCCTCCAGGATGCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCA CCCCCCGGACAGCAGCCCCCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGTCAGC CTCCAGTGCCACTCCCTGGGCAGCAGCAGCCAGTGCCGAGCTACCCAGGATACCCGGGGTCTGG GACTGTCACCCCCGCTGTGCCCCCAACCCAGTTTGGAAGCCGAGGCACCATCACTGATGCTCCC GGCTTTGACCCCCTGCGAGATGCCGAGGTCCTGCGGAAGGCCATGAAAGGCTTCGGGACGGATG AGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGCAGCGGCAGCAGATCCTACTTTC CTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGAACTGTCAGGAAACTTT GAGAAGACAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAGATAAAGGAAG CCATCAAGGGGGTTGGCACTGATGAAGCCTGCCTGATTGAGATCCTCGCTTCCCGCAGCAATGA GCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGGCCATT CGAAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATG AAAGCACAAACGTGGACATGTCACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGA GAACCGCCTGGGAACAGACGAGTCCAAGTTCAATGCGGTTCTGTGCTCCCGGAGCCGGGCCCAC CTGGTAGCAGTTTTCAATGAGTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCC GGGAGATGTCCGGGGACCTGGAGGAGGGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCC AGCCTTCTTTGCGGAGAGGCTCAACAAGGCCATGAGGGGGGCAGGAACAAAGGACCGGACCCTG ATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCTGGACATCAGATCAGAGTATAAGCGGA TGTACGGCAAGTCGCTGTACCACGACATCTCGGGAGATACTTCAGGGGATTACCGGAAGATTCT GCTGAAGATCTGTGGTGGCAATGACTGAACAGTGACTGGTGGCTCACTTCTGCCCACCTGCCGG CAACACCAGTGCCAGGAAAAGGCCAAAAGAATGTCTGTTTCTAACAAATCCACAAATAGCCCCG AGATTCACCGTCCTAGAGCTTAGGCCTGTCTTCCACCCCTCCTGACCCGTATAGTGTGCCACAG GACCTGGGTCGGTCTAGAACTCTCTCAGGATGCCTTTTCTACCCCATCCCTCACAGCCTCTTGC TGCTAAAATAGATGTTTCATTTTTCTGACTCATGCAATCATTCCCCTTTGCCTGTGGCTAAGAC TTGGCTTCATTTCGTCATGTAATTGTATATTTTTATTTGGAGGCATATTTTCTTTTCTTACAGT CATTGCCAGACAGAGGCATACAAGTCTGTTTGCTGCATACACATTTCTGGTGAGGGCGACTGGG TGGGTGAAGCACCGTGTCCTCGCTGAGGAGAGAAAGGGAGGCGTGCCTGAGAAGGTAGCCTGTG CATCTGGTGAGTGTGTCACGAGCTTTGTTACTGCCAAACTCACTCCTTTTTAGAAAAAACAAAA AAAAAGGGCCAGAAAGTCATTCCTTCCATCTTCCTTGCAGAAACCACGAGAACAAAGCCAGTTC CCTGTCAGTGACAGGGCTTCTTGTAATTTGTGGTATGTGCCTTAAACCTGAATGTCTGTAGCCA AAACTTGTTTCCACATTAAGAGTCAGCCAGCTCTGGAATGGTCTGGAAATGTCA Download Select all
Length	2486

CDS Information

Location	join(32817..32871,34763..34878,36320..36709,38365..38452, 38694..38788,39481..39594,41535..41625,42065..42144, 42273..42329,43650..43743,46483..46578,47653..47711, 47915..48037,49766..49825)
CDS Sequence	>gi\|22165429:239-1756 Homo sapiens annexin A11 (ANXA11), transcript variant a, mRNA ATGAGCTACCCTGGCTATCCCCCGCCCCCAGGTGGCTACCCACCAGCTGCACCAGGTGGTGGTCCCTGGG GAGGTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGG GCAGTTCAACCAGGACTATCTCTCGGGAATGGCGGCCAACATGTCTGGGACATTTGGAGGAGCCAACATG CCCAACCTGTACCCTGGGGCCCCTGGGGCTGGCTACCCACCAGTGCCCCCTGGCGGCTTTGGGCAGCCCC CCTCTGCCCAGCAGCCTGTTCCTCCCTATGGGATGTATCCACCCCCAGGAGGAAACCCACCCTCCAGGAT GCCCTCATATCCGCCATACCCAGGGGCCCCTGTGCCGGGCCAGCCCATGCCACCCCCCGGACAGCAGCCC CCAGGGGCCTACCCTGGGCAGCCACCAGTGACCTACCCTGGTCAGCCTCCAGTGCCACTCCCTGGGCAGC AGCAGCCAGTGCCGAGCTACCCAGGATACCCGGGGTCTGGGACTGTCACCCCCGCTGTGCCCCCAACCCA GTTTGGAAGCCGAGGCACCATCACTGATGCTCCCGGCTTTGACCCCCTGCGAGATGCCGAGGTCCTGCGG AAGGCCATGAAAGGCTTCGGGACGGATGAGCAGGCCATCATTGACTGCCTGGGGAGTCGCTCCAACAAGC AGCGGCAGCAGATCCTACTTTCCTTCAAGACGGCTTACGGCAAGGATTTGATCAAAGATCTGAAATCTGA ACTGTCAGGAAACTTTGAGAAGACAATCTTGGCTCTGATGAAGACCCCAGTCCTCTTTGACATTTATGAG ATAAAGGAAGCCATCAAGGGGGTTGGCACTGATGAAGCCTGCCTGATTGAGATCCTCGCTTCCCGCAGCA ATGAGCACATCCGAGAATTAAACAGAGCCTACAAAGCAGAATTCAAAAAGACCCTGGAAGAGGCCATTCG AAGCGACACATCAGGGCACTTCCAGCGGCTCCTCATCTCTCTCTCTCAGGGAAACCGTGATGAAAGCACA AACGTGGACATGTCACTCGCCCAGAGAGATGCCCAGGAGCTGTATGCGGCCGGGGAGAACCGCCTGGGAA CAGACGAGTCCAAGTTCAATGCGGTTCTGTGCTCCCGGAGCCGGGCCCACCTGGTAGCAGTTTTCAATGA GTACCAGAGAATGACAGGCCGGGACATTGAGAAGAGCATCTGCCGGGAGATGTCCGGGGACCTGGAGGAG GGCATGCTGGCCGTGGTGAAATGTCTCAAGAATACCCCAGCCTTCTTTGCGGAGAGGCTCAACAAGGCCA TGAGGGGGGCAGGAACAAAGGACCGGACCCTGATTCGCATCATGGTGTCTCGCAGCGAGACCGACCTCCT GGACATCAGATCAGAGTATAAGCGGATGTACGGCAAGTCGCTGTACCACGACATCTCGGGAGATACTTCA GGGGATTACCGGAAGATTCTGCTGAAGATCTGTGGTGGCAATGACTGA Download Select all
CCDS ID	CCDS7364.1

Protein Information

Protein ID	NP_001148.1
Protein Name	Annexin A11
Molecular Wt. (Da)	54259
Protein Sequence	>311 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGT FGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPV PGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRG TITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKS ELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKK TLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLC SRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAG TKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGND Download Select all
Length	505
Uniprot ID	P78325
Ensembl Protein ID	ENSP00000453855

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
C	S-Nitrosylation	294
C	S-Nitrosylation	294
C	S-Nitrosylation	294
Y	Phosphorylation	365;-
Y	Phosphorylation	365;-
Y	Phosphorylation	365;-
Y	Phosphorylation	482;-
Y	Phosphorylation	482;-
Y	Phosphorylation	482;-
K	Acetylation	255
K	Acetylation	255
K	Acetylation	255
K	Acetylation	479
K	Acetylation	479
K	Acetylation	479
K	Acetylation	248
K	Acetylation	248
K	Acetylation	248
T	Phosphorylation	321
T	Phosphorylation	321
T	Phosphorylation	321
S	Phosphorylation	462
S	Phosphorylation	462
S	Phosphorylation	462
T	Phosphorylation	464
T	Phosphorylation	464
T	Phosphorylation	464

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
2026	ENO2	573	NP_001966.1	yeast 2-hybrid	16169070
3189	HNRNPH3	3818	NP_036339.1	yeast 2-hybrid	16169070
5359	PLSCR1	8855	NP_066928.1	yeast 2-hybrid	16189514
6277	S100A6	237	NP_055439.1	in vitro;in vivo	12 601 007 129 961 900 000 000
6717	SRI	1680	NP_003121.1	in vitro	9268363
10016	PDCD6	3035	NP_037364.1	in vitro;yeast 2-hybrid	11883939
85365	ALG2	9716	NP_149078.1	in vitro;yeast 2-hybrid	11883939

Pathway Information

No matching records could be found.

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
pfam00191	435-500	Annexin
cl02574	435-500	Annexin superfamily
pfam00191	204-269	Annexin
cl02574	204-269	Annexin superfamily
pfam00191	276-341	Annexin
cl02574	276-341	Annexin superfamily
pfam00191	359-425	Annexin
cl02574	359-425	Annexin superfamily
smart00335	448-498	ANX
smart00335	289-341	ANX
smart00335	217-269	ANX
smart00335	373-425	ANX
PHA03378	75-194	PHA03378
pfam04503	71-190	SSDP
pfam03276	75-167	Gag_spuma
pfam09770	69-187	PAT1
pfam06346	66-200	Drf_FH1
pfam07223	71-194	DUF1421
pfam03154	62-199	Atrophin-1
pfam03154	70-187	Atrophin-1
pfam07271	71-202	Cytadhesin_P30
PHA02682	39-223	PHA02682
PRK07764	75-192	PRK07764
pfam07117	78-199	DUF1373
PHA03247	68-190	PHA03247

Ontology Information

HPRD ID	3777
Molecular Class	Calcium binding protein
Molecular Function	Metallopeptidase activity (GO:0008237)
Biological Process	Protein metabolism (GO:0019538)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

Mechanism	Polymorhpism/Up-regulation
Biomarker	-
Drug Target	-
Biological Process	Signal transduction

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO

CoReCG

Search results:

General Information

Evidence Information

Gene Details

mRNA Information

CDS Information

Protein Information

Post-translational Modification Information (Source : HPRD)

Enzyme Information

PPi Information

Pathway Information

Structure Information

Domain Information

Ontology Information

SNP Information

Drug Information

External Links

Important Information