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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
HSPA9 3313 heat shock 70kDa protein 9 (mortalin)  5GRP75, PBP74, mot-2, mthsp75 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24023782   2013Cell line : -

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : 62

Stage : TNM stage II, III

 PCR Unknown--


Gene Details



NC_000005.9 (137890571..137911318, complement)

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Gene Type protein coding
Gene Family Heat shock proteins / HSP70
Description This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010]  
Chromosome 5
Location 5q31.1
Start 137890571  
End 137911318  
Strand -  
Gene Sequence

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Length 20748  
OMIM ID 600548   
HGNC ID HGNC:5244   
Unigene ID Hs.184233   
Ensembl ID ENSG00000113013   
PharmGKB ID PA162391712   

mRNA Information


mRNA ID NM_004134.6
Exon join(1..392,1504..1562,1780..1867,4489..4670,6581..6705, 7908..7981,8069..8175,8467..8629,8912..9004,13841..14050, 15539..15766,16973..17077,17644..17761,18134..18228, 18764..18856,19038..19178,19516..20748)  
mRNA Sequence

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Length 3506  



CDS Information


   
Location 312..2351
CDS Sequence

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CCDS ID CCDS4208.1



Protein Information


      
Protein IDNP_004125.3
Protein Nameheat shock 70kDa protein 9 (mortalin)
Molecular Wt. (Da)0
Protein Sequence

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Length 679  
Uniprot IDP45985
Ensembl Protein ID ENSP00000262445  



Post-translational Modification Information (Source : HPRD)


Residue Type site
CS-Nitrosylation487
SPhosphorylation200;-
YPhosphorylation568;-
KAcetylation300
KAcetylation288
KAcetylation135
KAcetylation138
KAcetylation567
KAcetylation646
KAcetylation143
KAcetylation345
KAcetylation234
KAcetylation595
SPhosphorylation378
SPhosphorylation616
SPhosphorylation638
SPhosphorylation639
TPhosphorylation62
TPhosphorylation111
TPhosphorylation120

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

                                             
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
2246FGF1567NP_000791.1in vitro;in vivo;yeast 2-hybrid10510314   
7157TP531859NP_000537.3in vitro;in vivo11900485   
7184HSP90B11860NP_003290.1in vitro;in vivo12470827   


Pathway Information


            
Pathway Name Pathway ID
RNA degradation hsa03018
Tuberculosis hsa05152


Structure Information


No matching records could be found.

Domain Information




ID Location Description
cd1173352-428  HSPA9-like_NBD
cl1703752-428  NBD_sugar-kinase_HSP70_actin superfamily
cd1023452-428  HSPA9-Ssq1-like_NBD
cd1173455-428  Ssq1_like_NBD
cd1024153-426  HSPA5-like_NBD
cd1023356-429  HSPA1-2_6-8-like_NBD
cd1017056-426  HSP70_NBD
cd1023655-425  HscA_like_NBD
cd1023556-426  HscC_like_NBD
cd1022854-428  HSPA4_like_NDB
cd1023755-430  HSPA13-like_NBD
cd1023854-426  HSPA14-like_NBD
cd1173954-429  HSPH1_NBD
cd1023056-425  HYOU1-like_NBD
cd1173754-429  HSPA4_NBD
cd1173257-424  HSP105-110_like_NBD
cd1023254-425  ScSsz1p_like_NBD
cd1173854-429  HSPA4L_NBD
cd1023156-423  YegD_like
cd1022955-425  HSPA12_like_NBD
cd1022556-423  MreB_like
cd10227218-420  ParM_like
cd00012174-256  NBD_sugar-kinase_HSP70_actin
pfam02782346-429  FGGY_C
cd07808329-430  FGGY_D-XK_EcXK-like
cd07809328-441  FGGY_D-XK_1
cd07791335-449  FGGY_GK2_bacteria
cd07805346-434  FGGY_XK_like_2
cd07774346-423  FGGY_1
PRK0029052-673  dnaK
TIGR0235055-653  prok_dnaK
PTZ0040051-676  PTZ00400
pfam0001255-653  HSP70
PTZ0018646-679  PTZ00186
CHL0009453-662  dnaK
PRK1341153-662  PRK13411
PRK1341053-660  PRK13410
COG044355-654  DnaK
PLN0318455-668  PLN03184
PTZ0000952-624  PTZ00009
PRK0518356-644  hscA
TIGR0199155-644  HscA
PRK0143355-654  hscA
TIGR0090456-421  mreB
pfam0672356-423  MreB_Mbl
PRK1167856-407  PRK11678
PRK13928190-291  PRK13928
PRK1393056-423  PRK13930
TIGR02529170-273  EutJ
COG4820170-271  EutJ
PRK13929174-420  PRK13929
COG107755-338  MreB
PRK15080166-256  PRK15080
TIGR01312332-460  XylB
PRK13927190-290  PRK13927
COG1070346-430  XylB
PTZ00121565-677  PTZ00121


Ontology Information


   
HPRD ID7284
Molecular ClassChaperone
Molecular FunctionRNA binding (GO:0003723)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO