CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
BIRC5	332	baculoviral IAP repeat containing 5	17	EPR-1, survivin

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24338523	2014	Cell line : - Source : - Sample Type : Blood samples No. of Sample : 92 CRC patients and 60 healthy volunteers Stage : TNM Stage I-IV	real time RT- PCR	Up-regulation	-	Serum cell free BIRC5 mRNA is a promising non-invasive biomarker for diagnosis and prognosis of CRC. Cell free BIRC5 mRNA levels were significantly increased in serum of CRC (P <0.001), and significantly correlated with tumor differentiation (P=0.035), regional lymph node metastasis (P <0.001) and TNM stage (P< 0.001).
23405201	2013	Cell line : - Source : Tsuchiya General Hospital in Hiroshima. Sample Type : CRC tumor and Normal tissue No. of Sample : 40 Stage : TNM Stage I-IV	Immunoblotting, Indirect immunofluorescence, Immunoprecipitation	Up-regulation	-	The detergent soluble cytoplasmic Survivin might be a promising predictive biomarker for lymph node and distant metastases of colorectal cancer. An anti-apoptotic function of detergent-soluble Survivin in interphase cells experiencing anoikis is mediated at least via XIAP/IB-/NF-Kappa B signaling.

Gene Details

Chromosome 17 - NC_000017.11 (78214196..78225635)
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Gene Type	protein coding
Gene Family	Baculoviral IAP repeat containing
Description	This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Chromosome	17
Location	17q25.3
Start	78214196
End	78225635
Strand	+
Gene Sequence	>gi\|568815581:78214196-78225635 Homo sapiens chromosome 17, GRCh38.p2 Primary Assembly CCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATT AACCGCCAGATTTGAATCGCGGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGC CCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTTCTTGGAGGG CTGCGCCTGCACCCCGGAGCGGGTGAGACTGCCCGGCCTCCTGGGGTCCCCCACGCCCGCCTTGCCCTGT CCCTAGCGAGGCCACTGTGACTGGGCCTCGGGGGTACAAGCCGCCCTCCCCTCCCCGTCCTGTCCCCAGC GAGGCCACTGTGGCTGGGCCCCTTGGGTCCAGGCCGGCCTCCCCTCCCTGCTTTGTCCCCATCGAGGCCT TTGTGGCTGGGCCTCGGGGTTCCGGGCTGCCACGTCCACTCACGAGCTGTGCTGTCCCTTGCAGATGGCC GAGGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGG AGCTGGAAGGCTGGGAGCCAGATGACGACCCCATGTAAGTCTTCTCTGGCCAGCCTCGATGGGCTTTGTT TTGAACTGAGTTGTCAAAAGATTTGAGTTGCAAAGACACTTAGTATGGGAGGGTTGCTTTCCACCCTCAT TGCTTCTTAAACAGCTGTTGTGAACGGATACCTCTCTATATGCTGGTGCCTTGGTGATGCTTACAACCTA ATTAAATCTCATTTGACCAAAATGCCTTGGGGTGGACGTAAGATGCCTGATGCCTTTCATGTTCAACAGA ATACATCAGCAGACCCTGTTGTTGTGAACTCCCAGGAACGTCCAAGTGCTTTTTTTGAGATTTTTTAAAA AACAGTTTAATTGAAATATAACCTACACAGCACAAAAATTACCCTTTGAAAGTGTGCACTTCACACTTTC GGAGGCTGAGGCGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCTGCCTGGCCAACTTGGCGAAACCCC GTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTAGCGCACGCCCGTAATCCCAGCTACTCGGGAGG CTAAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGTGCCAATGCACTC CAGCCTCGGCGACAGAGCGAGACTCCGTCATAAAAATAAAAAATTGAAAAAAAAAAAAGAAAGAAAGCAT ATACTTCAGTGTTGTTCTGGATTTTTTTCTTCAAGATGCCTAGTTAATGACAATGAAATTCTGTACTCGG ATGGTATCTGTCTTTCCACACTGTAATGCCATATTCTTTTCTCACCTTTTTTTCTGTCGGATTCAGTTGC TTCCACAGCTTTAATTTTTTTCCCCTGGAGAATCACCCCAGTTGTTTTTCTTTTTGGCCAGAAGAGAGTA GCTGTTTTTTTTCTTAGTATGTTTGCTATGGTGGTTATACTGCATCCCCGTAATCACTGGGAAAAGATCA GTGGTATTCTTCTTGAAAATGAATAAGTGTTATGATATTTTCAGATTAGAGTTACAACTGGCTGTCTTTT TGGACTTTGTGTGGCCATGTTTTCATTGTAATGCAGTTCTGGTAACGGTGATAGTCAGTTATACAGGGAG ACTCCCCTAGCAGAAAATGAGAGTGTGAGCTAGGGGGTCCCTTGGGGAACCCGGGGCAATAATGCCCTTC TCTGCCCTTAATCCTTACAGTGGGCCGGGCACGGTGGCTTACGCCTGTAATACCAGCACTTTGGGAGGCC GAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCTTGGCTAATACGGTGAAACCCCGTCTCCACT AAAAATACAAAAAATTAGCCGGGCGTGGTGGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCA GGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGG GCGACAGAATGAGACTCCGTCTCAAAAAAAAAAAAAAAAGAAAAAAATCTTTACAGTGGATTACATAACA ATTCCAGTGAAATGAAATTACTTCAAACAGTTCCTTGAGAATGTTGGAGGGATTTGACATGTAATTCCTT TGGACATATACCATGTAACACTTTTCCAACTAATTGCTAAGGAAGTCCAGATAAAATAGATACATTAGCC ACACAGATGTGGGGGGAGATGTCCACAGGGAGAGAGAAGGTGCTAAGAGGTGCCATATGGGAATGTGGCT TGGGCAAAGCACTGATGCCATCAACTTCAGACTTGACGTCTTACTCCTGAGGCAGAGCAGGGTGTGCCTG TGGAGGGCGTGGGGAGGTGGCCCGTGGGGAGTGGACTGCCGCTTTAATCCCTTCAGCTGCCTTTCCGCTG TTGTTTTGATTTTTCTAGAGAGGAACATAAAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAAGAAG CAGTTTGAAGAATTAACCCTTGGTGAATTTTTGAAACTGGACAGAGAAAGAGCCAAGAACAAAATTGTAT GTATTGGGAATAAGAACTGCTCAAACCCTGTTCAATGTCTTTAGCACTAAACTACCTAGTCCCTCAAAGG GACTCTGTGTTTTCCTCAGGAAGCATTTTTTTTTTTTTTCTGAGATAGAGTTTCACTCTTGTTGCCCAGG CTGGAGTGCAATGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCTCGGGTTCAAGTGATTCTCCTGCCT CAGCCTCCCAAGTAACTGGGATTACAGGGAAGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGA GATGGGGTTTCACCACATTGCCCAGGCTGGTCTTGAACTCCTGACCTCGTGATTCGCCCACCTTGGCCTC CCAAAGTGCTGGGATTACAGGCGTGAACCACCACGCCTGGCTTTTTTTTTTTTGTTCTGAGACACAGTTT CACTCTGTTACCCAGGCTGGAGTGGGGTGGCCTGATCTCGGATCACTGCAACCTCCGCCTCCTGGGCTCA AGTGATTTGCCTGCTTCAGCCTCCCAAGTAGCCGAGATTACAGGCATGTGCCACCACACCCAGGTAATTT TTGTATTTTTGGTAGAGACGAGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGA TCCACCCGCCTCAGCCTCCCAAAGTGCTGAGATTATAGGTGTGAGCCACCACACCTGGCCTCAGGAAGTA TTTTTATTTTTAAATTTATTTATTTATTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTAGAGTGCAGCG ACGGGATCTCGGCTCACTGCAAGCTCCGCCCCCCAGGTTCAAGCCATTCTCCTGCCTCAGCCTCCCGAGT AGCTGGGACTACAGGCGCCCGCCACCACACCCGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGTTTTC ACCGTGTTAGCCAGGAGGGTCTCGATCTCCTGACCTCGTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTG GGATTACAGGTGTGAGCCACCACACCCGGCTATTTTTATTTTTTTGAGACAGGGACTCACTCTGTCACCT GGGCTGCAGTGCAGTGGTACACCATAGCTCACTGCAGCCTCGAACTCCTGAGCTCAAGTGATCCTCCCAC CTCATCCTCCCAAGTAATTGGGACTACAGGCGCACCCCACCATGCCCACCTTATTTATTTATTTATTTAT TTATTTATTTATTTTCATAGAGATGAGGGTTCCCTGTGTTGTCCAGGCTGGTCTTGAACTCCTGAGCTCA AGGGATCCTTTTGCCTGGGCCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACCGTGCCCAGCTAGGAA TCATTTTTAAAGCCCCTAGGATGTCTGTGTGATTTTAAAGCTCCTGGAGTGTGGCCGGTATAAGTATATA CCGGTATAAGTAAATCCCACATTTTGTGTCAGTATTTACTAGAAACTTAGTCATTTATCTGAAGTTGAAA TGTAACTGGGCTTTATTTATTTATTTATTTATTTATTTATTTTTAATTTTTTTTTTTGAGACGAGTCTCA CTTTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCCGGGGTCAAG CGATTCTCCTGCCTTAGCCTCCCGAGTAGCTGGGACTACAGGCACGCACCACCATGCCTGGCTAATTTTT GTATTTTTAGTAGACGGGGTTTCACCATGCTGGCCAAGCTGGTCTCAAACTCCTGACCTTGTGATCTGCC CGCTTTAGCCTCCCAGAGTGCTGGGATTACAGGCATGAGCCACCATGCGTGGTCTTTTTAAAATTTTTTG ATTTTTTTTTTTTTTGAGACAGAGCCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCAGCT CACTACAAGCTCCGCCTCCCGGGTTCACGCCATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAG GTGCCCACCACCACGCCTGGCTAATTTTTTTTGGTATTTTTATTAGAGACAAGGTTTCATCATGTTGGCC AGGCTGGTCTCAAACTCCTGACCTCAAGTGATCTGCCTGCCTCGGCCTCCCAAAGCGCTGAGATTACAGG TGTGATCTACTGCACCAGGCCTGGGCGTCATATATTCTTATTTGCTAAGTCTGGCAGCCCCACACAGAAT AAGTACTGGGGGATTCCATATCCTTGTAGCAAAGCCCTGGGTGGAGAGTCAGGAGATGTTGTAGTTCTGT CTCTGCCACTTGCAGACTTTGAGTTTAAGCCAGTCGTGCTCATGCTTTCCTTGCTAAATAGAGGTTAGAC CCCCTATCCCATGGTTTCTCAGGTTGCTTTTCAGCTTGAAAATTGTATTCCTTTGTAGAGATCAGCGTAA AATAATTCTGTCCTTATATGTGGCTTTATTTTAATTTGAGACAGAGTGTCACTCAGTCGCCCAGGCTGGA GTGTGGTGGTGCGATCTTGGCTCACTGCGACCTCCACCTCCCAGGTTCAAGCGATTCTCGTGCCTCAGGC TCCCAAGTAGCTGAGATTATAGGTGTGTGCCACCAGGCCCAGCTAACTTTTGTATTTTTAGTAGAGACAG GGTTTTGCCATGTTGGCTAAGCTGGTCTCGAACTCCTGGCCTCAAGTGATCTGCCCGCCTTGGCATCCCA AAGTGCTGGGATTACAGGTGTGAACCACCACACCTGGCCTCAATATAGTGGCTTTTAAGTGCTAAGGACT GAGATTGTGTTTTGTCAGGAAGAGGCCAGTTGTGGGTGAAGCATGCTGTGAGAGAGCTTGTCACCTGGTT GAGGTTGTGGGAGCTGCAGCGTGGGAACTGGAAAGTGGGCTGGGGATCATCTTTTTCCAGGTCAGGGGTC AGCCAGCTTTTCTGCAGCGTGCCATAGACCATCTCTTAGCCCTCGTGGGTCAGAGTCTCTGTTGCATATT GTCTTTTGTTGTTTTTCACAACCTTTTAGAAACATAAAAAGCATTCTTAGCCCGTGGGCTGGACAAAAAA AGGCCATGACGGGCTGTATGGATTTGGCCCAGCAGGCCCTTGCTTGCCAAGCCCTGTTTTAGACAAGGAG CAGCTTGTGTGCCTGGAACCATCATGGGCACAGGGGAGGAGCAGAGTGGATGTGGAGGTGTGAGCTGGAA ACCAGGTCCCAGAGCGCTGAGAAAGACAGAGGGTTTTTGCCCTTGCAAATAGAGCAACTGAAATCTGACA CCATCCAGTTCCAGAAAGCCCTGAAGTGCTGGTGGACGCTGCGGGGTGCTCCGCTCTAGGGTTACAGGGA TGAAGATGCAGTCTGGTAGGGGGAGTCCACTCACCTGTTGGAAGATGTGATTAAGAAAAGTAGACTTTCA GGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGAGGT CAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTTTACTAAAAATACAAAAAATTAGCTG GGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGG AGGTGGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTC TCAAAAAAAAAAAAAAAAAGTAGGCTTTCATGATGTGTGAGCTGAAGGCGCAGTAGGCAGAAGTAGAGGC CTCAGTCCCTGCAGGAGACCTCTCGGTCTCTATCTCCTGATAGTCAGACCCAGCCACACTGGAAAGAGGG GAGACATTACAGCCTGCAAGAAAAGTAGGGAGATTTAAAAACTGCTTGGCTTTTATTTTGAACTGTTTTT TTTGTTTGTTTGTTTTCCCCAATTCAGAATACAGAATACTTTTATGGATTTGTTTTTATTACTTTAATTT TGAAACAATATAATCTTTTTTTTGTTGTTTTTTTGAGACGGGGTCTTACTCTGTCACCCAGGCTGAGTGC AGTGGTGTGATCTTGGCTCACCTCAGCCTCGACCCCCTGGGCTCAAATGATTCTCCCACCTCAGCTTCCC AAGTAGCTGGGACCACAGGTGCGTGTGTTGCGCTATACAAATCCTGAAGACAAGGATGCTGTTGCTGGTG ATGCTGGGGATTCCCAAGATCCCAGATTTGATGGCAGGATGCCCCTGTCTGCTGCCTTGCCAGGGTGCCA GGAGGGCGCTGCTGTGGAAGCTGAGGCCCGGCCATCCAGGGCGATGCATTGGGCGCTGATTCTTGTTCCT GCTGCTGCCTCGGTGCTTAGCTTTTGAAACAATGAAATAAATTAGAACCAGTGTGAAAATCGATCAGGAA ATAAATTTAATGTGGAAATAAACTGAACAACTTAGTTCTTCATAAGAGTTTACTTGGTAAATACTTGTGA TGAGGACAAAACGAAGCACTAGAAGGAGAGGCGAGTTGTAGACCTGGGTGGCAGGAGTGTTTTGTTTGTT TTCTTTGGCAGGGTCTTGCTCTGTTGCTCAGGCTGGAGTACAGTGGCGCAATCACAGCTCACTATAGCCT CGACCTCCTGGACTCAAGCAATCCTCCTGCCTCAGCCTCCCAGTAGCTGGGACTACAGGCGCATGCCACC ATGCCTGGCTAATTTTAAATTTTTTTTTTTCTCTTTTTTGAGATGGAATCTCACTCTGTCGCCCAGGCTG GAGTGCAGTGGCGTGATCTCGGCTGACGGCAAGCTCCGCCTCCCAGGTTCACTCCATTCGCCTGCCTCAG CCTCCCAAGTAGCTGGGACTACAGGCGCTGGGATTACAAACCCAAACCCAAAGTGCTGGGATTACAGGCG TGAGCCACCGCACCCGGCCTGTTTTGTCTTTCAATAGCAAGAGTTGTGTTTGCTTCGCCCCTACCTTTAG TGGAAAAATGTATAAAATGGAGATATTGACCTCCACATTGGGGTGGTTAAATTATAGCATGTATGCAAAG GAGCTTCGCTAATTTAAGGCTTTTTTGAAAGAGAAGAAACTGAATAATCCATGTGTGTATATATATTTTA AAAGCCATGGTCATCTTTCCATATCAGTAAAGCTGAGGCTCCCTGGGACTGCAGAGTTGTCCATCACAGT CCATTATAAGTGCGCTGCTGGGCCAGGTGCAGTGGCTTGTGCCTGAATCCCAGCACTTTGGGAGGCCAAG GCAGGAGGATTCATTGAGCCCAGGAGTTTTGAGGCGAGCCTGGGCAATGTGGCCAGACCTCATCTCTTCA AAAAATACACAAAAAATTAGCCAGGCATGGTGGCACGTGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGG TGGGAGGATCACTTTGAGCCTTGCAGGTCAAAGCTGCAGTAAGCCATGATCTTGCCACTGCATTCCAGCC TGGATGACAGAGCGAGACCCTGTCTCTAAAAAAAAAAAAACCAAACGGTGCACTGTTTTCTTTTTTCTTA TCAATTTATTATTTTTAAATTAAATTTTCTTTTAATAATTTATAAATTATAAATTTATATTAAAAAATGA CAAATTTTTATTACTTATACATGAGGTAAAACTTAGGATATATAAAGTACATATTGAAAAGTAATTTTTT GGCTGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGTGGCGGGCAGATCACATGAGAT CATGAGTTCGAGACCAACCTGACCAACATGGAGAGACCCCATCTCTACTAAAAATACAAAATTAGCCGGG GTGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCTCTTGAACCCGGGAGG CAGAGGTTGCGGTGAGCCAAGATCGTGCCTTTGCACACCAGCCAAGGCAACAAGAGCGAAAGTCCGTCTC AAAAAAAAAGTAATTTTTTTTAAGTTAACCTCTGTCAGCAAACAAATTTAACCCAATAAAGGTCTTTGTT TTTTAATGTAGTAGAGGAGTTAGGGTTTATAAAAAATATGGTAGGGAAGGGGGTCCCTGGATTTGCTAAT GTGATTGTCATTTGCCCCTTAGGAGAGAGCTCTGTTAGCAGAATGAAAAAATTGGAAGCCAGATTCAGGG AGGGACTGGAAGCAAAAGAATTTCTGTTCGAGGAAGAGCCTGATGTTTGCCAGGGTCTGTTTAACTGGAC ATGAAGAGGAAGGCTCTGGACTTTCCTCCAGGAGTTTCAGGAGAAAGGTAGGGCAGTGGTTAAGAGCAGA GCTCTGCCTAGACTAGCTGGGGTGCCTAGACTAGCTGGGGTGCCCAGACTAGCTGGGGTGCCTAGACTAG CTGGGTACTTTGAGTGGCTCCTTCAGCCTGGACCTCGGTTTCCTCACCTGTATAGTAGAGATATGGGAGC ACCCAGCGCAGGATCACTGTGAACATAAATCAGTTAATGGAGGAAGCAGGTAGAGTGGTGCTGGGTGCAT ACCAAGCACTCCGTCAGTGTTTCCTGTTATTCGATGATTAGGAGGCAGCTTAAACTAGAGGGAGTTGAGC TGAATCAGGATGTTTGTCCCAGGTAGCTGGGAATCTGCCTAGCCCAGTGCCCAGTTTATTTAGGTGCTCT CTCAGTGTTCCCTGATTGTTTTTTCCTTTGTCATCTTATCTACAGGATGTGACTGGGAAGCTCTGGTTTC AGTGTCATGTGTCTATTCTTTATTTCCAGGCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAAC TGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGCTGCCT GGTCCCAGAGTGGCTGCACCACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTGTGGGCCCCTTA GCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAACTGTGCTCTTGTTTTGTCTTGA AAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTCT CTCTCTTTTTTGGGGGCTCATTTTTGCTGTTTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAA GAAGGCAGTGTCCCTTTTGCTAGAGCTGACAGCTTTGTTCGCGTGGGCAGAGCCTTCCACAGTGAATGTG TCTGGACCTCATGTTGTTGAGGCTGTCACAGTCCTGAGTGTGGACTTGGCAGGTGCCTGTTGAATCTGAG CTGCAGGTTCCTTATCTGTCACACCTGTGCCTCCTCAGAGGACAGTTTTTTTGTTGTTGTGTTTTTTTGT TTTTTTTTTTTTGGTAGATGCATGACTTGTGTGTGATGAGAGAATGGAGACAGAGTCCCTGGCTCCTCTA CTGTTTAACAACATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAGAATAGCACAAACTACAATTAA AACTAAGCACAAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGAGGAGACAGAAT AGAGTGATAGGAAGCGTCTGGCAGATACTCCTTTTGCCACTGCTGTGTGATTAGACAGGCCCAGTGAGCC GCGGGGCACATGCTGGCCGCTCCTCCCTCAGAAAAAGGCAGTGGCCTAAATCCTTTTTAAATGACTTGGC TCGATGCTGTGGGGGACTGGCTGGGCTGCTGCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTGTCA CGTTCTCCACACGGGGGAGAGACGCAGTCCGCCCAGGTCCCCGCTTTCTTTGGAGGCAGCAGCTCCCGCA GGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCCCTCCTCCCTGTCATAGAGCTGCAGGGTGGAT TGTTACAGCTTCGCTGGAAACCTCTGGAGGTCATCTCGGCTGTTCCTGAGAAATAAAAAGCCTGTCATTT CAAACACTGCTGTGGACCCTACTGGGTTTTTAAAATATTGTCAGTTTTTCATCGTCGTCCCTAGCCTGCC AACAGCCATCTGCCCAGACAGCCGCAGTGAGGATGAGCGTCCTGGCAGAGACGCAGTTGTCTCTGGGCGC TTGCCAGAGCCACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAAT GCACTTCAGACCCACTTATTTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGA GAATATCACAGTGGTTTTTGTTAGCAGAAAATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTATTTT TGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTAATAACTGTTGCTTAGTAATTGGCTTTGTAGA GAAGCTGGAAAAAAATGGTTTTGTCTTCAACTCCTTTGCATGCCAGGCGGTGATGTGGATCTCGGCTTCT GTGAGCCTGTGCTGTGGGCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCCCGCCTGCCACGGCCTTTCCTT AAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCTGAAAGCTTCCTCGACATCTGTTAATAA AGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACATGTCCATTTTT CAGGTTCTCTAAGTTGGAGTGGAGTCTGGGAAGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTTC CAATGGCAGGTTAGAGCCCCTCGGGCCAACTGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCA GAAGAGACCAGCAAGCCAAACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCACAAT TGCCAATAAAGTCTCATGTGGTTTTATCTA Download Select all
Length	11440
OMIM ID	603352
HGNC ID	HGNC:593
Unigene ID	Hs.744872
Ensembl ID	ENSG00000089685
PharmGKB ID	-

mRNA Information

mRNA ID	NM_001012271.1
Exon	join(1..232,485..594,1771..1839,2469..2586,9270..11440)
mRNA Sequence	>332 CCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGC GCCATTAACCGCCAGATTTGAATCGCGGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTG CCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAGAA CTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGAGGCTGGCTTCATCCAC TGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCT GGGAGCCAGATGACGACCCCATGCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAACT GCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGC TGCCTGGTCCCAGAGTGGCTGCACCACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTG TGGGCCCCTTAGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAACTGTG CTCTTGTTTTGTCTTGAAAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTA ACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTTTTGGGGGCTCATTTTTGCTGTTTTGATTCCCG GGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTGCTAGAGCTGACAGCTT TGTTCGCGTGGGCAGAGCCTTCCACAGTGAATGTGTCTGGACCTCATGTTGTTGAGGCTGTCAC AGTCCTGAGTGTGGACTTGGCAGGTGCCTGTTGAATCTGAGCTGCAGGTTCCTTATCTGTCACA CCTGTGCCTCCTCAGAGGACAGTTTTTTTGTTGTTGTGTTTTTTTGTTTTTTTTTTTTTGGTAG ATGCATGACTTGTGTGTGATGAGAGAATGGAGACAGAGTCCCTGGCTCCTCTACTGTTTAACAA CATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAGAATAGCACAAACTACAATTAAAACTA AGCACAAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGAGGAGACAGAA TAGAGTGATAGGAAGCGTCTGGCAGATACTCCTTTTGCCACTGCTGTGTGATTAGACAGGCCCA GTGAGCCGCGGGGCACATGCTGGCCGCTCCTCCCTCAGAAAAAGGCAGTGGCCTAAATCCTTTT TAAATGACTTGGCTCGATGCTGTGGGGGACTGGCTGGGCTGCTGCAGGCCGTGTGTCTGTCAGC CCAACCTTCACATCTGTCACGTTCTCCACACGGGGGAGAGACGCAGTCCGCCCAGGTCCCCGCT TTCTTTGGAGGCAGCAGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCC CTCCTCCCTGTCATAGAGCTGCAGGGTGGATTGTTACAGCTTCGCTGGAAACCTCTGGAGGTCA TCTCGGCTGTTCCTGAGAAATAAAAAGCCTGTCATTTCAAACACTGCTGTGGACCCTACTGGGT TTTTAAAATATTGTCAGTTTTTCATCGTCGTCCCTAGCCTGCCAACAGCCATCTGCCCAGACAG CCGCAGTGAGGATGAGCGTCCTGGCAGAGACGCAGTTGTCTCTGGGCGCTTGCCAGAGCCACGA ACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAATGCACTTCAG ACCCACTTATTTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGAGAA TATCACAGTGGTTTTTGTTAGCAGAAAATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTAT TTTTGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTAATAACTGTTGCTTAGTAATTGG CTTTGTAGAGAAGCTGGAAAAAAATGGTTTTGTCTTCAACTCCTTTGCATGCCAGGCGGTGATG TGGATCTCGGCTTCTGTGAGCCTGTGCTGTGGGCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCC CGCCTGCCACGGCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCT GAAAGCTTCCTCGACATCTGTTAATAAAGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACT TTCTTTCAGATACATGTCCACATGTCCATTTTTCAGGTTCTCTAAGTTGGAGTGGAGTCTGGGA AGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTTCCAATGGCAGGTTAGAGCCCCTCGGG CCAACTGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCAGAAGAGACCAGCAAGCCAA ACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCACAATTGCCAATAAAGTC TCATGTGGTTTTATCTAAAAAAAAAAAAAAAAAAAAAAAAA Download Select all
Length	2537

CDS Information

Location	join(122..232,485..594,9270..9462)
CDS Sequence	>lcl\|NM_001012270.1_cds_NP_001012270.1_1 [gene=BIRC5] [protein=baculoviral IAP repeat-containing protein 5 isoform 2] [protein_id=NP_001012270.1] [location=122..535] ATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTTCTCAAGGACCACCGCATCTCTACATTCAAGA ACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGAGGCTGGCTTCATCCACTGCCC CACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCTGGGAGCCAGAT GACGACCCCATGCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAACTGCGGAGAAAGTGCGCCG TGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGCTGCCTGGTCCCAGAGTGGCTGCA CCACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTGTGGGCCCCTTAGCAATGTCTTAG Download Select all
CCDS ID	CCDS32751.1

Protein Information

Protein ID	NP_001012271.1
Protein Name	baculoviral IAP repeat containing 5
Molecular Wt. (Da)	18506
Protein Sequence	>332 MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKEL EGWEPDDDPIGPGTVAYACNTSTLGGRGGRITREEHKKHSSGCAFLSVKKQFEELTLGEFLKLD RERAKNKIAKETNNKKKEFEETAEKVRRAIEQLAAMD Download Select all
Length	165
Uniprot ID	P01241
Ensembl Protein ID	ENSP00000312673

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	34
T	Phosphorylation	34
T	Phosphorylation	34

Enzyme Information

No matching records could be found.

PPi Information

No STRING Network could be found.

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
836	CASP3	2799	NP_004337.2	in vitro	9850056
840	CASP7	3457	NP_203124.1	in vitro	11 170 436 985 005 600 000 000
842	CASP9	3756	NP_001220.2	in vivo	11069302
1019	CDK4	447	NP_000066.1	in vitro	10713676
5921	RASA1	745	NP_002881.1	in vivo	11976319
7514	XPO1	3975	NP_003391.1	in vitro	17099693

Pathway Information

Pathway Name	Pathway ID
Colorectal cancer	hsa05210
Hepatitis B	hsa05161
Hippo signaling pathway	hsa04390
Pathways in cancer	hsa05200

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00022	16-87	BIR
cl00035	16-87	BIR superfamily
smart00238	14-87	BIR
pfam00653	18-87	BIR

Ontology Information

HPRD ID	1996
Molecular Class	Adapter molecule
Molecular Function	Carboxy-lyase activity (GO:0016831)
Biological Process	Metabolism (GO:0008152); Energy pathways (GO:0006091)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO