CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
APOB	338	apolipoprotein B	2	-

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
25024621	2014	Cell line : - Source : Department of Anus and Intestine Surgery, Provincial Cancer Hospital of Shanxi Province. Sample Type : CRC tumor No. of Sample : 260 CRC including 166 rectum carcinoma and 94 colon cancer Stage : TNM Stage I-IV.	Measurement of lipid levels	Down-regulation	-	Serum levels of TCH, LDL-C, ApoA-I and ApoB were significantly lower in patients with colorectal cancer than in patients with benign colorectal disease and healthy controls.

Gene Details

NC_000002.11 (21224301..21266945, complement)
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Gene Type	protein coding
Gene Family	Apolipoproteins
Description	This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
Chromosome	2
Location	2p24-p23
Start	21224301
End	21266945
Strand	-
Gene Sequence	>gi\|568815596:c21044073-20999218 Homo sapiens chromosome 2, GRCh38.p2 Primary Assembly ATTCCCACCGGGACCTGCGGGGCTGAGTGCCCTTCTCGGTTGCTGCCGCTGAGGAGCCCGCCCAGCCAGC CAGGGCCGCGAGGCCGAGGCCAGGCCGCAGCCCAGGAGCCGCCCCACCGCAGCTGGCGATGGACCCGCCG AGGCCCGCGCTGCTGGCGCTGCTGGCGCTGCCTGCGCTGCTGCTGCTGCTGCTGGCGGGCGCCAGGGCCG GTGAGTGCGCGGCCGCTCTGCGGGCGCAGAGGGAGCGGGAGGGAGCCGGCGGCACGAGGTTGGCCGGGGC AGCCTGGGCCTAGGCCAGAGGGAGGGCAGCCACAGGGTCCAGGGCGAGTGGGGGGATTGGACCAGCTGGC GGCCCCTGCAGGCTCAGGATGGGGGGCGCGGGATGGAGGGGCTGAGGAGGGGGTCTCCGGAGCCTGCCTC CCTCCTGAAAGGTGAAACCTGTGCCGGTGGTCCCCCTGTCGGGCCCTAGCACCCGCTGGGAAGACGTGGG AAGCTCACAGATTTCTTTCTCCTGTCTTACAGAAGAGGAAATGCTGGAAAATGTCAGCCTGGTCTGTCCA AGTAAGGCATCTGCGCATGGGGCGTGGAAGGGCGCCCAGCCCCGTGCACTCTCCTACACCCGGGTCCCTG AGGGCCTCCCACTCTACAGGGCTGAGATGGCATCGTGGTGTGCCTTGCTCTGACCCCAGGAAGCAAGTTC CCTGAGCCTCTGCCCACACCCAAGGGATGCCAACTCTCTTCTACCTGGCCTTCTGTTCTGTCCCAAAAGT TCAGCCTGGGGGCGGGGGAGGGAAGGGATTGTCTCTCCGCTGGCCTGTGCACACTTTGAAGAAACATCAC TGTCCTGTTTATCAGTGACTAGTCATTGATTCGAAGCATGTGAGGGTGAGGAAATACTGACTTTAACCTT TGTGAAGAAATCGAACCTCCACCCCCTTCCTATTTACCTGACCCCTGGGGGTTAAAGGAACTGGCCTCCA AGCGCGACCCTGTGTGCTGGAGCCGCGGGGCGGACTTCTGATGGGGCAGCACCGCCATCTAGTGGCCGTC TGTCATCACTGCAGCTGGACTCAGGACCCAGATGTTCTTTTTCTTCAATTGTTCAGAAAATTCCTCTCAA CTACAGTGGAAACCTCCAGAAATTCTTTTCTAGGAGTTTGTTAAGTTAGTTACGCTTAATGCTTAATGAA CTTTGCCTTAAGTATTTGGTAGTCTTAGAGTCACGGAATTACGGCGTGTTCAAGCTAAAAAAGCATTAGA GATAGTACTATTTGCGTAATGTTGTCATCTCTTAATTTGCCAGAGGGTCTCTCATGCAGATTTTCTGAGC CCCATTACTTGACACTTGTCACTCCCTTCCCTGTGCCTCAGATGAGATATTCAAGACATGCCAGCCAATT TAAACATTAGCCTCAGCAAAAACATAATGGAGAAGTCAAATCTATAAAGGAAAATTAAGTATAAAGTCAA TTAAAAAATAATTTGAGTTGAATTACCATTTTTAATTCTCTATGCCACTGCCCCTCTCTGCCCAGAATTG GCTGTCCTTGGGAGAGCTATTTCTGCTATGTGGCTGACGTATTTCTCCCCACGTTAGAAGATGCGACCCG ATTCAAGCACCTCCGGAAGTACACATACAACTATGAGGCTGAGAGTTCCAGTGGAGTCCCTGGGACTGCT GATTCAAGAAGTGCCACCAGGATCAACTGCAAGGTATGGAGGATGCAGGCAGGAGGGACCTAGAGCCCAC AGCTTTCCCCCAGCCCTGTTCCAGCGGGCGCCCAACACGCGACCTTCCCGGAGGGTGTGTACTGAGCAAA CGCAGAACATCCCAGAACTGTTGTAATCTGATCAAAGCACTGGGACTTTGCCTCTGTTTGTAAGTCAGCC ACATTGCTGAGATGTGGTCTGCCCCCACCAAATTTCGCAAGTCAGAAGTATTTTCCCGTTAACTTCCCAG ATGCAATAGGAATCCATGATCTAGATTAGCAGCAGTGTGGGTCTGTAGATTTCAGCGTGAGAGAGGCCCA GTAGGTGAGCTATGGGAGGCAGGCAACTCGGAATCGCACTGTGAAATGCAGTTTTTATAATTTAAGTCAA ACAGAATCTGTTGCTGAAAAATGAATGGAAAGAAGAAAAAAATATAAACATACAGTTTGTTCTAAAATAA AACTTTGCTTATTATTGAGACTGGTTGTACTCATGTTACATACATGTGGAGCAGATCTACAGGCTGCTAT TGGGGTTTGGGTGGGGAAGAGAAGTCAAGCTGAGCAGTCACCTTTTTTTAGAGAGTACCGTAGCTCTTGT ATGTGCTGTCCAATATGGTAGACATGAGCCACATTGGGCTATTTAAATGGAATGAAATTAAAAATTCATA TTCGTTGTCACATTAGCTGCATTTCAACTGCTCAACAGCCACCCTGGCTACTGGCTCCCATATTGAACAG CACACATGTACAACATTTCTATAAAGTTATTTGAATAGTGCTGGATAATAAGTAGGAATCCGTTGAAACT CCAGCTATATGCAAAGCTCTAAATAGGCCCTAATAGATATAACCAGTTTTTTGGGTGACATTAAGGAGAC ATTTGCTGTGGAAACGAAGGATGGCCCTCTTCCTGCTTTCTGTTTTTCTTCTTCACTTTCACTCCTAGTC TGCAGCGCTTCTATTTAACCACAGCTCTTTATAATTAAAGTGAGTAACTTTAGAACCAATAAAAGGACAT CCTCCTTCCCATGCCTAGGGGCAAACTTAAGAAATGTGTTACCCGGGAGGGGGAAAACGTCAGCAATAGG ACTAAGTCTAGGTTGGTGCACAGAGAACCCAGGAGGCATGTTGATAAGGCATGTGGTGTTGAGGCGCAGG CAGTGGTGTTCCCAGCACCATTCCCTTTGGTGCTCTGATTAGAGATTAAGCCCTGGGCTTCAGGGGCCAC CTCTCATTCTTGATAGACAACCTCAATGCTCTGCTACCCTGAATTCTCAGGTTGAGCTGGAGGTTCCCCA GCTCTGCAGCTTCATCCTGAAGACCAGCCAGTGCACCCTGAAAGAGGTGTATGGCTTCAACCCTGAGGGC AAAGCCTTGCTGAAGAAAACCAAGAACTCTGAGGAGTTTGCTGCAGCCATGTCCAGGTAAGTCATGTTGT ACATGAGCACACGCATGTGTGTGTGTCCGCTGAGGTATGAACTTGTGTGTTTGCACCAGGCACGGATGTG ACTGTAAGTATTTGTATTCCGTATCCATCGTGGATCAGGGAATTACTGAGTTTTCACAATCATCAAAAAG AGAGAAGCATTAGTTAACCTTCCCTAGTTAGGTTCCTTTAATTATCATTTTCATGTGTTTCTAAAAATCT CATGCTTTAAACTTCTTGAGATTATAAAACTGAGATGCTTTGTTTAAACAAGTGAATTCTTATTTAAAGA ACTAGTCAAGACTAGTGCTTGGTGGTCTTTGGTGTGGGGTCCCAGAGGCACTGGCTGCTGTGGCCGGCAC ATGGCGGGGCAGGGTCTGTTCACCGCAGGGCAGAGGAGCACCAAGGCTTCGGTGGCTCCCCCTCCTAGGC TGGCATTCAGCCACTGCACGCTGATCGGCCACTGCAGCTGCATCTCTGCTGACTGGTCAGGGCCCATGTC GCACCCATTGTAAATATTTTCAACATCACCCCTGCCTCATCCTCAATCACAGTTTGTAGGGTCCTAGGTG TGTATGAATACAGGCAGGATAGAGTTGTTAACTTGGTAGCATCAGAAAACTCTGTCTGTATTAGTCTGTT TTCATGCTGCTGATAAAGACATACCTGAGACTGGGCAATTTACAAAAGAAAGGTTTATTGGACTCACAGT TCCACGTGGCTGGGGAGGTCTCACAATCATGGCGGAAGGTGAGGGACAGCAAGTCACATCTTATGTAGAT GGTGGCTGGCAAAGAGAGCTTGTGCAGAGAAACTCCTGTTTTTAGAACCATCAGATCTCCCGACACCCAT CTGCAATCACGAGAACAGCACGGGAAAGACCTGCCCCCATGATTCAATCACCTCCCCCCGGGTCCCTCCC ACAACACGTGGGAATTATGAGAGCTACGAGACGAAATTTGGGTGGGGACGCAGAGCCAAACCATATCACC ATCCTTGCCCATTTTTCAGTTTTGCTAAACATTAGATTCAGATGCCAGTCCTTTCTTGCCAAAATAGGCT GTGAGGCTTCTTTCTTTCCTATGCTTTATTTTCTCCAAGACTTAACTGTATATGAGGGAGAGGGGTATGG TGGCAGGAGGAAAGAGTGGTTTATTTTTTGGTCCTTGGTCTTCTCCAAATACAGAAGAGACTCCTGTTCT TGAAAAGGAGGGCTTTCCATGTTTGCATCTTCATGACTTTAACTGTCTTTTTTAAAAATTGACATACAAT AATTATACATATTTATTGAGAACATAGTGATATTTTGATACATGTAATGTATGGTGATCAGATCAGAGTA ATTAGCATACCCATCATCTCAAACATTTATCATTTCTTCGTGTTGGGAACTTTCTGAGAGAGTGTAGGCT GTGGGAGATAAGTCCGTCACCTTTTCCTCCTGATGTAACCAGAGTGGCTGCAGCCAGGTCCTCAGAAACT CAGAGAGTACCCAGTGGGAAATCCCTAAGACCAAAGTCAGCATGGGCTTCAGCCATGGCCTGACACCATA CAAAAGAATGACTGTCCAACAAGTGTATGAAAATAAGCTCCAATTCACTGGTAGTCAAGAAATGCGAATT AATGTAACAACAAGATATTTATCTGCTTTTACCCATCATACTGCAAAACTGGAAAACAGTGATAGCACCT GTTGCTGGCAGGCCAGTGAGGAAAAGTGTGCTGTCCTGAGCTGCTGGTGGAAACGAGAGCCATCAGGCAA TATCTACTGTAATTTAAAATACTTAATACCCTTTGACACAGATATTTTAGTCTTTGGGACTCTAGCCCAT GAAAATAAAAGCAGTAATGTGTGAAGATAGGCACATAAGGATGTTTGTTTTGGTATTGTTTGTGTGGTTT AAAAAAAATCCAGAAAGAGAGAGGGCAAATGCCATCAAATGGGGCAATGTGTGAATAAATTATATTTAGC CATGGAATGGAATGTTCTGCATGCAGCTTTTAAAAAAATCTGTTAGAGCTGTACCAAGTGACTCAGAAGG ATTTTTGTGAAGTATAATTAAGTGAGAAAAACAAGATAAAAGTATGCATAATACAATGCCACTTGTATAA AACAAACAATGGCAAAATCTTTGTATGACTCTGTTTGCACTCACCCATGTTTACAGAGGATTGTATGAGT GTGCAGAAACAAATGGAACAACCACTCGGGTGTCCGTATGGGGAGGATGGGCAAAGAGACTGATATGGGT GGAGAACAGAGCAGGGCTGGATGAGCCAAGCAAAAAAAGTTAAAACACAGCTGGACCTGGTGGCTCATGC CTGTAGTCCCAGCACTTTGGGAGGCCGAGGAGGGAGAATCACCTGAGGTCAGGAGTTTGAGACCAGCCTG GCCAACATGGTGAAAACTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGATGGCACATGCCAGTAG TCCTAGCTACTCCGGAGGCTGAGGCAGGAGAATCACTTGATCCCAGGAGGTGGAGGTTGCAGTGAGCTGA GGTTGCGCCATTGCACTCCAGCCCGGGCGACCGAGCGAGACTCCATTTCAAAAAAAGAAAAAGAAAAAAG AAAAAAAGAAAAAAAAAGAATCACCAAAACTTATGTATATGTGCATACTTTTTTGAAAATGTATGTCTAT GTGTAGCTATATTCTATATTTACAAATAAATGATGTCAGAAGAACAATTGGTTAAAAAAATATGAGAAAA GAAACTTCAGTGCCACCCAGCTTACTTCCAGCAAGTTGTAATGGAGAAGGACATTTCCGTGACCATCCTC TCTCTGGGACAGGTATGAGCTCAAGCTGGCCATTCCAGAAGGGAAGCAGGTTTTCCTTTACCCGGAGAAA GATGAACCTACTTACATCCTGAACATCAAGAGGGGCATCATTTCTGCCCTCCTGGTTCCCCCAGAGACAG AAGAAGCCAAGCAAGTGTTGTTTCTGGTGAGGATTTAGAAAGCTGATAGCAGTGGCCCTTGAAACTCATC TTCATGTGTTAGAGACCAGTCCTACCATATACAAAGCAGATCACTGAGTCAGCTCCATGACTAGTTACAT AGGAAGCCCTGGATTGGCGTGAAATACTGGTGCCCGAGGTTCCTCCTGCCCCTTAGGCTCACTGACAGAT CATCCCAAGCAGGCTTATCAGGTTGGGTCTAATTTTAAAACAGTCATTGAGGAGTCCTGGCCACCCCACC CCTGCTTTTGTTTGATGCTTCACCTGTGTTTGCTGGGTTATGGTGTACACAGTAAATCCTGTGTGTATTT TAAACACCAAAAATAATGGGATCTGTTGCTGGTCTCTTTTACGAATTTCAGGTTTCACTGTGAGACAGAA TTCATTTCACCTCAGTCCCATGAGCACTTTTGTGTGTTCTAATTTCTCTACGACACCATAATGGGAGAAG ACACCGATGCAACCTGCGGAGGCCTTTCTGCAGACCCACCTTTAACTGGTTTTCTCTCTCCCAACTTGGG CTGGCCAGGCACTAGCAAGACCACACTCTGCATAGGAAGAAAAAGAAAGTCCCTCCCAAAGCTAGATTCC TTCTGCTTTTTCTTTCACGATCCCCACCCCATCCCTCCCAAGTACCCAAGGATGTTGCCCGTGTTGAATA CATGTGGTTGCATCTTCTTCCTCCATAGGATACCGTGTATGGAAACTGCTCCACTCACTTTACCGTCAAG ACGAGGAAGGGCAATGTGGCAACAGAAATATCCACTGAAAGAGACCTGGGGCAGTGTGATCGCTTCAAGC CCATCCGCACAGGCATCAGCCCACTTGCTCTCATCAAAGGCATGGTAAGTCCCATGTCAGCACTGTCGTG CACAGCAAGGAGCATCCTCTTATTAATACAATTCCAGAACTTTTGAGCTAGTGGGCACCTTTGAGGACAG CCTGCCCTGGCTGTTTTTTATACAGACTAGAGATAGGACCCTGAGCAGGCACGGGAAGGTCTGCCCAGGC TTCACGGCCTGGGATCAGTTGAGCCAAGGCTTGAGTCAGGCTCCTCCCTCCCAGCCCAGAGCTCTGTCTT TCCTCCTGTCCTTCTGTCACTGGCACCAAACTGCCTCTAATCTCATCACTTGAGAGTAATGACTACTCAC CTCTGAGAAGGTTCCGGGGATGGATGTAGGGCAGCAAAACCACCTTCTGTTCTTTTCTGCACAAGGACTC CTTGTGCCAGCTCCAAGCCTCTGGCCTTTGAAGAAGTCCCAAGACCTGTGTTCTCCCCCTCTCCCTCATC CCATGAAGTGGAGTGACTTAGAGTGCTCCAGCTTCTTGTCCTTCCACCCCCAGTACCACCCTGACCAAAC ATGGCCCCACTGCCACCGGCCTGGAGCACCCTCTCCTCTCTGTTAACTGGGGCCATGGAGCACCATATTA CCTGAGCCTGCCTGACCCCTGCAACATCTTCCCTGATATGAGCCCCAGCCTGTCTCAGTGAACATGAATA ACTTGGGCAATCACTGTCATGCTGGGCGCTGTTCCTGGTCATTGTCCTTAGGGTTGAAAACAGGGAGTCT GATGACCATGAGTGCCACAGTCAGAAGAGGATAATGCACTGGCTTAGGGGTCTTTTCTGAGCATCTGCTG TTTGCTCAACCCCACTCTGGGCAGCACCAAGGAAGGGACAGTGGCAGATGAACCATGGACCTTCCCCTCA GGATGCTTCCAGTCTAATGCAGGAGCCAGGTCAATAAAGTATACGTGGTATACTCAATAAGGTGATAAGC TGAACAGTGCAGACAAGAAGTCCTGGGCCTGACCAGGAAGGAGAAAGAATTATTCATGTAGCTCAGCGGG CAACATTTCATGGAAGATGTGGAGCAGGAACCCAAAAAATGCAAAGAATATGTAAATGAAAGAGACATGT AAGAATGGGCTTTTGGGCAAAGAAAAGTTACTGAGCAGGTGTGTGAGGGGCTATGTGGTGGGATGGGCAT GTGGAGGATACAAAGTTTAGACATTGTCCAGTGAGGGTGGAAAAAGAGGAGTCTACAGCTTGACTCAGCT TTGGGGATGCCGACTTGTTGCACCCCCTGGTCTAAATGTCAAGTACCCAGTTATCTTCTTTCTCTGAGTT TATCTAGTGGTACAGGACTCCTGCTCCCTTCTACCTTGAAGGTAAATGCTTTTAACAGAAGATACAGGGA CTGATCAAAATGCTCGTCTCCAATCTCTTTCATAGACCCGCCCCTTGTCAACTCTGATCAGCAGCAGCCA GTCCTGTCAGTACACACTGGACGCTAAGAGGAAGCATGTGGCAGAAGCCATCTGCAAGGAGCAACACCTC TTCCTGCCTTTCTCCTACAAGTAGGTCATGTGATGCACCCCTGATTTGTCATTTAATGGGTCAGTGTGAA CTGAACACTTCTCAAGTGCTCTGTTCCAGGCAAACCTGTGCCTGGGAGGGAGGAATGGAGAGGGATAAAA TGCCGCCCCTCCCTGTCCCCCTTTTTAAGCGAACAGGCCATTTGGCAGAAAAGTCCTAGGCATGCAAAAC AATCCAAGACCAACAAAAGATATCTAAGACCCATTCTTTAAGGGCTGTAGATCCAGAAAACCTGAGGATC ACTGCAGGGTACCCTGGTTAGAAAAGGTTTCATGGAAGATTTGGGATACTGACTGGAAACTTGTGTATCC AAATCCACTTTGAAAACTGATAATCAATGAATATATATTGAGTAACTGCCATATTCTTGGCTCTATGTTG TGGAAGATACGAAAGAATTTTGAGACATTGCACTAGTTCCTACCTCTGGCCACTCCAGACTAGTGGAGAG TATAAGGCACGCATGTCTTTTTGATGGGAGGATAACTAGCGTGACCAGGAAGAGGTGGATGTTATTCATT CAGGGCCAACAATGGCTGGATTTACCCATGCTTTGAAAGATGGGCAGGACTTGGGTAGATGCAGAGACAG GGAAAACCTTCAACATGGAAAGAATAGTATGTTCTGGCCATCCGTGACATGGTGTGCTTCCTTGGTTACC AGGAATAAGTATGGGATGGTAGCACAAGTGACACAGACTTTGAAACTTGAAGACACACCAAAGATCAACA GCCGCTTCTTTGGTGAAGGTAAGAGTTTCTGTCCACATAGTTGCTGGAAAATCTACTCAAGATGTGCCTA TCATGGCTTAGCCACTTGCTGAGCCCTGTTAAATGTCTGCTGACTAACAAGTGATACAGACACTGGTGTT CTGGCTACCTCTAGTGAGAAAGCAAACTCATTTCATGATGTCAAGTTGCAATGGCATAAAGGAAAAGAAG TTCCCAAAGCTACTTAGGCATTTGTAAATAGAAAACTGGAATCCTAAGTTTAACATGACATATTTGATAG AACTGACATCACCCATCCTGTGATAAGATCCAGAGCTGTCCCAGACGAGGTGGACCAAGTGGGAGAGAAC CTTCAGAGTCTGGCCAGATAGTAACCTCAGGAGTCAGTCTTTAGAGGTAGAAGGAACTCTAACAATCTCA AGTCCAACCCTTACCCAGTATTGTATTGTATTTATATCTGTCCAAATTCCTTCTTGTACATTACCTCATT GTCCTTTTTGCTCATAGCAACCTGTGATGTCAGGTGGTAGAGATGTGATTTTATACCTATTCTACAGAGG AGACAGTGACACAGAGAGGCTTAGAGTTTGATGTAGTCAAGGCCGCAGAATATTAGAGGGGGGAAAATAA GTGCCAGGTTGTAATCTAAGCCAGGACTATTCTCATTACACCACATTTCCATGATGACTTTTACCTCTCT TCCTGGCATAGGTCACAGTAGGTGGTGGAGAGGATACAAAAGTGTCTCCCCTCCCCACAAGCTGCTGGTA GACCCAATTAGAAGAAATGGTGATAAGCACCCATGTGCCTGGTCCCAGTTGTAACCATGTCAACAGTAGC ACCTCCTCACCAATTATTTCAAGCTAAGGGTAACCTGATGATAGACTCAGACAAGTCTGGATTCCACTTT AGCTCTACCTCTTAGACCCTGAGAGCTCTTGGGAAACCTAAGTTGCTCATCTCTGGGTCACACTTCCTCA TCTCTGGGTCTCATCTCTTTGTCTCATCTCTGGGACTCAGAGCTGAGATCCAGGGATGAGCAATTTACAT GGCCCAAAAACTCTGTGGGTCTCAGAAGCAGGGCTGAATTTATCATTAAATTGAACAATAATGCCACCCC ACAGGGATAGGATGATGAGTCAGTGAAAACAAGTCAATCACCTATGGCAGAGCCAGATCTAGCAGGCATT GAATACAGGATAGTTTCTTTCCCTTTTCCCCTGTGCTGATACTCCACAATTTCCAGCTTCCAGTAGACAA AGATATGGTTGAGATGAAGAAAGCTAGAGTTCCTTTGACACTTTCCATCTTCCAGGTACTAAGAAGATGG GCCTCGCATTTGAGAGCACCAAATCCACATCACCTCCAAAGCAGGCCGAAGCTGTTTTGAAGACTCTCCA GGAACTGAAAAAACTAACCATCTCTGAGCAAAATATCCAGAGAGCTAATCTCTTCAATAAGCTGGTTACT GAGCTGAGAGGCCTCAGTGATGAAGCAGTCACATCTCTCTTGCCACAGCTGATTGAGGTGTCCAGGTATC TAATGGTTACAGCTCAACTTTTTATAAAACTGATGGTAACTGACTGAACTTTCAAACCTTGGCCAAATGG AGAATCTCAGGGACCATTTGGATATCAATCCAGTTAATCAATTAGTCAATCAGTTCATGATTGCTGGATA GAGAACTATCAGCTGCTGCGCTGAGTTCCATGAAACACACACGCGCATACTGTGTTCAAGGCAGCTATGT ATTTGTGTGTTAAAACAGAAGGAGAATAGTTCCCACATTTTGATGGGTAACTTTTAATTCCTAGGTCTAT TGCAGGTGCTCTCCAGAAGCTTATAGGCTGGTGGAGAGAGAACTCAGACGAAAAATATAATATGATTTCT CTACCCTTCAAGGCACTGGCTTTAAGTGCTATGAAGGTGAGAGAAGGGACTGAGGCCAGGAATGAGACCC AGCTAATGTTGGCCAGGCATATTCTGTGTGCTGGCCAAAGGACTGTGATAACAGTCTTCTTGTTGCTACA GATCCACAGTCCCCTCTTGGAACTTTTCTCGATTGGGCTTCTTCTGTGGGTAATATTCCTAAGGAAAGCA TCATGGTTCTGAGCTCCAAGTTGGGTTTTGAAGTTAGATTTGAATAGTGAATGAGGTGATTAAGGGCTCT CCTGGCAGAGGACACACCATGAGCAATATTTTATGTGCCCTGAAGGTGGTCTGTATAACTTTATCCATGT CTTTCTTCTCAGCCCCATCACTTTACAAGCCTTGGTTCAGTGTGGACAGCCTCAGTGCTCCACTCACATC CTCCAGTGGCTGAAACGTGTGCATGCCAACCCCCTTCTGATAGATGTGGTCACCTACCTGGTGGCCCTGA TCCCCGAGCCCTCAGCACAGCAGCTGCGAGAGATCTTCAACATGGCGAGGGATCAGCGCAGCCGAGCCAC CTTGTATGCGCTGAGCCACGCGGTCAACAAGTGAGTTTCCACACTGTATTTCTCCTCCTAGGAGCAGAGG AACATCTTGCACCTCTGTGCATCTCTGTATTAAAACTGAACCCCTCCTTCCACTTTCAAACTCTGCTCCT TACTCTTGTGTTTTTTCTTGATCATTTTTGGGGTAATGACTTGAAATAAGAAATCAGCAAACACAAATTG AATTTTTAAAAATATTTTCTCTACATTATATTATAAAAGTTTTTGAACATAGCAAAGTTGACAGAATTTC ACAGGGAAAACCCCTAGAAAACCAGCTATCTCCTACTATTTAAGTGTTATTATATTTGCTTTATCACATA TACATCCATCCATTAATTCATCTTATTTTCTGAAGCATTTCAAAGTAAATTGCAAACATCAACACACTTT CCCCTAAGTATTACAGCTTGCATATTATTAACTTCAGTTCAATATTAGTTAGCAGTTTTTTCCTCTGAAT TTTTTTGTTTGTTTGTTTTGTTTTTTTTTGTTGTTGTTGTTTTTTTGAGATGGTCTCACTGTGTCACCCA GGCTGGAGTGCAGTGATGCAGTCACGGCTCACTGAAGCCTCAAATTCCTGGGCTGAAGTGATCCTCCCAC CTCAGCCTCCTGAGTAGCTGGGACCACAGGTGCATGCTACCATGCCCTGGCTAATTTTTGTATTCTTGGT AGATACAGGGTTTCACCATGTTGCTCAGGCTAGCAGGTTTTTCCTTTGATGAAATTTTTTGGCTTTTTCT TTTTTACATTTTTATATAAATTTATGTGGAACAAGTGTAATTTTGTTACATGAATAGATTGTGCAGTAGT TAAGTCAGGGCTTTCAGGGTATCCATCACCCAGACAACATATAGTGTACCCACTAAGTAATTTCTCACCA TCCATCTCCCTCCACTTCCACACCTTCTGAGTCTCAATTGTCTATCATTCCACACACTATGTCCTTGTGT GCACATTATTTCACTCCCACTTATAAATGACAACACGCAATATTTGTCTTTCTGTGACTGTCCTGTTTCA CTTAAGACAATGACCTCCAGTTCCATCCATGTTGCTGCAAATGACATGATTTTATTCTTTTTATGGCCGA ATAGTATTTTATTGCCTATACATTTCACATTTTTAATCCAATCGTCCATTGATAGACACTTAGGTTGATT CCATGTCTTTGCTATTGTGAATAGTGCTGTGATAAACATATGGGTGCAGGTTTCCTTTGGATATAATGAT TTCTTTTCCTTTAGGTATATACCCAGTAATGGGATTGTTGGATTTATTGGTAGTTCTATTTTTAGTTCTT TGAGAAATCTCTGTATTGTTTTCCATAGTGGTTGTACTTATTTACAATCCCATCAACAGTGATTAACTGT TTCCTTTTCTCTGTATCCTCACCAACAACTGTTATTTTTTGTCTTTTGAATAATGGCCCTCCTGACTCTT GTAAGATGTTATCTCATTGTGGTTTTAATTTACATTTCTCTAATGATTAGTAATGTTATGCATTTTTTCA TATGCCTATTGCCATTTGTATGTCTTCTTTTGAAAAAAATGTCTATTCATGTCCTTTGCCTACTTTTTAA TGGGATTATTTGGGGGATTTTTTTGTTGAGTTGTTTGAATTGCTTGTACATTCCGGATATTAGTACCCCA TTGGATGAATAGTTTGCAAATATTTTCTCCCATTCTGCAGGTTACCACCCTGTTGATTATTTGTTTTACT GTGCAGAAACTTTTTACTTTAATTAAGTTCTATTTGTCTATTTTTTGTTTTTGTTGTCTTTGCCTTTGAG GTCTTATTCACGAATTCTTTGTCTAGGCCAATGTCCAGAGAAGTTTTCCCTAGGTTTTCTTCTTGCATTT TTATAGTCTCAGGTCTTATATTTAAGTCTTTGATCCATCTTGAGTTGATTTTTTTATATGGTGACAGATA GGAGTCCAGTTTTATTCTTCTGCATATGGCAATCCATCTTTCCCAGCACCACTTATTGAAAAGGGTGTCC TTTCCCTAGTGTATGTTTTTGTCAATTTTGTCAAAGATCCGTTGACTGTAAGTATGTGACTTTATTTCTG GGTTCAGTATTCTGTTCCATTGATCTATGTGTCTATTTTTATGCCAGTACCATGCTGTTTAGATTACTAT AGCCTTGTTGTATAATCTGAAGTCAGGTAATGTGATGCCTCCAGCTATGTTCTTTTTGCTTAAAATTGCT TCAGCTATTCAGGCTCTTTTTGGATTCCATATGAATTTTATAATTATTTTTTCTAATTCACAAGTTTGGG TTTTAAGACAAACCTAACTGGGGTTACCAAGTCCTGACTCTCTTCTCTTATTCTGTAGCTATCATAAGAC AAACCCTACAGGGACCCAGGAGCTGCTGGACATTGCTAATTACCTGATGGAACAGATTCAAGATGACTGC ACTGGGGATGAAGATTACACCTATTTGATTCTGCGGGTAATCTCAGTCTTTTATATGACATACATCATTT CAGAAGCACTTTTCCTGGACACCTTTTACTTCCCTCTCCTGCACCCTGATGGGTTCTTGTTTCTTTTCTT CAATGCAGGTCATTGGAAATATGGGCCAAACCATGGAGCAGTTAACTCCAGAACTCAAGTCTTCAATCCT GAAATGTGTCCAAAGTACAAAGCCATCACTGATGATCCAGAAAGCTGCCATCCAGGCTCTGCGGAAAATG GAGCCTAAAGACAAGGTAAAGTCCACAAGAAGAGGTCTGAAAGTGAAAGTTTATTAACAAGGATTTGGAA GGTACTAGGGGAATGAGACTCTAGATTTCATCTACTGACTTTATTCTGCTGTTTCTTTCCTTTCCTTCCT TCCTTCCTTCCTTCCTTCCTCCCTCCCTCCCTTTCTTCTTTCCTTCCTTCCTTCCTTCTTTCGAGATGGA ATCTCACTCTATTGCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACTTCTGCCTCCTGGG TTCAAGCAATTCTCTCTGCCTCAGCCTCCTGAGTAACTGGGATTACAGGCATGTGCCATTACACCCAGCT AATTTTTGTATTTTTTAGTAGAGATGGAGTTTTGCCATGTTGGCCAGGCTGGTCTTGAGCTCCTGACCTC AGGTGATCCGCCTGCCTCAGCCTTGCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCTGGCCTCTA CTGTTTTCTAATTGCAAATTTCAACAAGCCTATTGACTTGACTGCCTAGCAGTATGTGACGTGAGAGAAA TACTTGACTTTGCTGCTATGTCAACATGCAGAACGTGAGATGTTTTTGCTTCCTACCGTCCACCTACCAG ATTGACCATCCCTCTCATCATGGAAAAACATGCTTAATTTTCCCCCAATAAGCTTAGGCTAGGATAGCCA ACTTGGCCCCCTCTTAGGTGCAAAGACTCCAGAACTTTGGAAACTACCCTATTTATTAGCCCCAAACTCT TACTACCCCTTCTCATCTTTATCCTCACATTAAAATAACTTACGTTAAAACAACTTGATTTTCACTTAGT GGTGGATCTCCAAACAAATCACAACTTGGCCATAATTTATGTGTTTTAATGGAATTGAATTCAACAGGCA TTCCACAGGCTTTTTCTGGGAACCCTTACTTGATAGTGCTCTAGGAAACACTGGCAAGAAGATTCAATAC CAGCATTTGAAGAACGATTACAGAGAAATTAGACCTGTGCTTAAGAAAGAGCTAGCAGACAATGCCAGTG TTTGCCAGGCATGTTCTGTGTTCTGACCACAGGACAGTGATAACCATCTCCTCTTTTGACTGCAGGACCA GGAGGTTCTTCTTCAGACTTTCCTTGATGATGCTTCTCCGGGAGATAAGCGACTGGCTGCCTATCTTATG TTGATGAGGAGTCCTTCACAGGCAGATATTAACAAAATTGTCCAAATTCTACCATGGGAACAGAATGAGC AAGTGAAGAACTTTGTGGCTTCCCATATTGCCAATATCTTGAACTCAGAAGAATTGGATATCCAAGAGTA AGTAAGAGCTATTCACCCCATATACCACTGAGGGCCCTGAGCTGGAATTCCAACCCTAGGTTTTGGCATA GCCACTGTCTGCCCTTGCTTCTGAAACAAACACTTGTGCAAATGTGTAGCAGATCTAGACCCAAAGACTT AGGGTCAATGAAATCAAGACATTTTGGTAGTGATTGGAAATCCATATTTACTTGGGGTGCAAGAGTCAAA GGATAATAACATGGTGTGTCAGCTCAAAATATACTTCTTCTTATCTAGTCTGAAAAAGTTAGTGAAAGAA GCTCTGAAAGAATCTCAACTTCCAACTGTCATGGACTTCAGAAAATTCTCTCGGAACTATCAACTCTACA AATCTGTTTCTCTTCCATCACTTGACCCAGCCTCAGCCAAAATAGAAGGGAATCTTATATTTGATCCAAA TAACTACCTTCCTAAAGAAAGCATGCTGAAAACTACCCTCACTGCCTTTGGATTTGCTTCAGCTGACCTC ATCGAGGTAAGTGTGAAGAGTTTGAGGTTCTCTAGCCCATTTTGTACAGCATCATAAACAGAGAGTCCCT GGGAGCCAGGAGCTACCCAGAGGAAAACTAAGAACCACCAGGCACTTCCTACCATGATTCTGAGGCTTTC TTCTTTCCCTCCTTCCCCGCCTTCCTCTCTCCCCGCTAGGGGTCACCTGAAGCATGACTTCTTAACATTA ATAGAAATGCAGGCCTGGCGAGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGG ATCATGAGGTCAGGATATCGACACCATCCTGGCTAACACGGTGAAAGCCCATCTCTACTAAAAATACAAA AAATTAGCCGGGCGTGGTGGCAGGCACCTGTAGTCCCAGCTACTTGGGAGGATGAGGCAGGAGAATGGCG TGAACCCAGGAGGCTGAGCTTGCAGTGAGCCGAGAGATTGCGCCACTGCGCTCCAGCCTGGGCGACAGAG CAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAATTGAAATGCAAATGTCTCGTCTTTAAGTCCCAA AGCCAAGGAAGCATATGTGCTGCCTAGTCAGATCTGCTTCAAATCTCAAATCACTCCCAACTCTGAATCC TTTGTTGAATTATTTGTCCTATCTGAACCTTAGCTGCCTCTTCTAGAAAAAAGCAAGTAATAAGGTCAAG ATTCTAGTGAGATTTTAATAAAGCAGCTCCTGTGAAATGCTAAGGTCAGCTCCTGGCCTGTGGTATTCAA ATACTTGTTTAGATAAATGGACATCAAGAGTGGGGACTACTAGGCTGGCATACAACAAAGAAACCTGATG CCATTTTCTTGTCTGATTTTCTTTCTCAGATTGGCTTGGAAGGAAAAGGCTTTGAGCCAACATTGGAAGC TCTTTTTGGGAAGCAAGGATTTTTCCCAGACAGTGTCAACAAAGCTTTGTACTGGGTTAATGGTCAAGTT CCTGATGGTGTCTCTAAGGTCTTAGTGGACCACTTTGGCTATACCAAAGATGATAAACATGAGCAGGTGT GTATTTGTGAAGTATCTTCTTAAGGAAAGCTTTGGGTCTCAATGCAAAAACAATTCTTTTCTAAGCATGG AAGTCCTCAAAATACTATCTAACTGAAGGGATAACTATGGTTTTTATCAACCAGACCTGCTGGGGTAAGG GCCAGTATCCTCTGCAGTTAAAGATCTCCTGAATTCAGTGTGCCCAGAAACCAGACTCACAATAAGTACT CTAGGATAACAAGAGTATGAACTCTGGGCTGGGTGTGGTGGTTCATGCCTGTAATCCCAGCACTTTGGGA GGCCAAGGTGGGCAGATCACAAGGTCAGGAATTTGAGACCAGCCTGGCCAACATACTGAAACCCCGTCTC TACTAAAAATACAAAAAAACTAGCTGGGCATGGTAGTGGGTGCCTGTAATCCTAGCTACTCGGGAGGCTG AGACAGGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCGAGATCACGCCGTTACACTCCAG CCCGGGTGACAGTGTGAGACTGTATCTTAAAAAAAAAAAAAGTATGAACTCTGGGCATAGATTTAATTCT AACTTCCCTGTCTTGAAGCTGTGCGCACTTGGGGAAGTTGGTTGATATTATGTGTATCTGTTTCTGTCTG TATCCCAGACTACTAATAACAGTCCAAACCTCACAAGGTTATTTAAAGACAATGAAATAAGGCATCTAAA ATGCCAAGCACAGTGCCTGATGCTGGCATTGGTTGTTCAATAAGCAGACACTATTACGAGTTCTAAATTA ATATTTTCATTATTATTAACTGCTGTCTTTGGCTCTCACTCCCATCAGTGCACTAGCAAATGAGACCAAA CTTCCACTTTGAAGCTAGCAATGAGCCCCCATTTAAGGAGGGAAATAGGTTGTATGATCTGGAGCTTATT CTTGAATTTTTTGCTACCCAAAGTGTGGTCTGGTCAGAAATACAGCTTCTCATGCTTCACCCACAATCTA CTGAATCAGAAGCGCATTTTAGCAAGACCTCATGTGACTTGTATGCACATTCAACTTTGCAGAGCAAGGC AGTAATTTACCCCTCCAGGCTCACTGTTGAGCACGAGCTCCATCTTCTAATTTCCTGACCCCCACTTGAG GCCGAGGATCTTTGATCTGCTTTGAGTCTGTCAGTTTCACATTTTTTTTTTCCCAATGCCTGGGCATCCA TCTCTGAGATTCTTCTTCTCTCTGAGAAGAACTTGTCTAGGATCAAGTGTTTTTCAAACTTCTGGTGAAT TTATATAACAGCTACATTTTCTTAAGAAACACCTTGTAGTCTTCACTGGTCAAAGAAGAGAAGGCTAAGC AGGGAACGGGTGGGGGATAGAGGATCTTCTAATCTTGAGGATCCTGGCATACTGGAGAATAGGGACCCCT CCTCTCATCCCACCACATCTTACTATGTCTACAGATTTTTTAATTAAGAATAGCTTTAGGAGTGCCACTA TCCCTGACAAGACCTTAGTTCTTTAATCTCTGCTTAGAGGAATTAGCCTGGACTTCAGTGTCTCCCTGTT CCTCACCTGGAGCATTTTTTAGGCCCATCCTGGCTGCATCAGACAGGTCCCACATTGGGAACTGAAAGGT GTTTGACATTGCTGACATCTCACTGGCCATTTTATTACTAAACTCTCAGGATATGGTAAATGGAATAATG CTCAGTGTTGAGAAGCTGATTAAAGATTTGAAATCCAAAGAAGTCCCGGAAGCCAGAGCCTACCTCCGCA TCTTGGGAGAGGAGCTTGGTTTTGCCAGTCTCCATGACCTCCAGCTCCTGGGAAAGCTGCTTCTGATGGG TGCCCGCACTCTGCAGGGGATCCCCCAGATGGTAAGTCAGCAGGCCCCACTGGGGGCCCATGAGACCAGA CGTTGGTTTTTTTTTAGATCGCCCAGACTCCCTTACGATCCCAGCTGCACAAGCCCGAAAAGATGCTTGT ACTTTCTTCAGAGATGGAGGTTTGCCTTGAATTTCACTGAAGATGACTCTTGGATCACATGGAAATGTTA ACATTTAGAAATTAAGCTATTCATAATGTTAGCTGTATTTTTAAGAGCATTAATTTATTCATCTGGAAAA CAATGTTCGGTATACCTTCCTCTACCTTTGCTGAAGGTCCTTTTATTTTTATTTTTATTTTTTTAATTTT TTGAGATGGAGTCTTGCTCCCAGGCTGGAGTGCAGTGATACAATCTCGGCTCACTGCAACTCTGCCTTCC GGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTGTGGACGTGCACCAGCATGCCCGG CTAATTTGTGTATCTTTAGTAGAGACAAGCCTGTTGACAACCATGTCAGGCTGGTTTCGAACTCCTGACC TCAAGTGATCCTCCAGCCTGGGCCTCCCACAGTGCTGGAATAACAGGTGTGAGCCACTGCACCTGACCTG AAGGTCCTTTTAAGATTGAAATGATACAATGATTATAAAAGAAAGTATTTGGCAAACTATAATTCACTAT CTAAATATGCTATAATTTTTATTATTAATTCATAAAAGGAAATATATAAATGTACTCCTATGGCTTGATT AAAAAAATGTTGACTTTAAGAAAACAGGTCTCAAGCTATTTTATTGAAATATTATTTAAAAAATAAAACC CAATGCAAATTGATATGTACATCATCTCAATAGGCCTTTGGTTTCAAAAAATTGATTTTATCATAATATA ATACATTTCAAGTACACCTTCACTTACAGTCAGACTCCAGAACACCAGAATTAAGCCATGGCATATATGA TACTTAAAGTCCATAAAGCTCTGAGGCCCAGCAATATTCTTAAGAGCCTTCTGAGTCCACTTGAAAATGA CATGATATCTATCTAGTGAAATTTCTTATATCCTGATTCACTGAAAACGGTAAAAACATCAGTTTGATCT TTATTTATCAAACTATTCAGCTCATCAAAATATGCTAGTCCTTCCTTTCCAGATAAAGAGGAATTACTCT CCAATGTATGGGAGGTTGTAATTAACAAAACCGACTTTAAAAAGACTTACTTTTATTTGCTCTCCCTTGT TGGGTCTACAGATTGGAGAGGTCATCAGGAAGGGCTCAAAGAATGACTTTTTTCTTCACTACATCTTCAT GGAGAATGCCTTTGAACTCCCCACTGGAGCTGGATTACAGTTGCAAATATCTTCATCTGGAGTCATTGCT CCCGGAGCCAAGGCTGGAGTAAAACTGGAAGTAGCCAACGTAAGATTCTGTTTGCCTTTTGATTTCTTAG GTTATTACTTTCTTCCAGGGTGCATTTCTTGTTAAAACATATTTAAAAATGTGTTTCCACTTCAAGACAA AATGCTTCATCATTGTAATCACCTCATTATTTTTTTATGAAAAACTTCAAGCTTCCACCAGAATGCACTA CCTCACTAGCTCCAGTAGTGGTATGGCCATAAGACAAGAACTCAGTTCTCTCAACAAATGAGTATTCCTA TCATCTTTTTAATCTGGTTTTGCCTCACGTTAACTCAGGTGCTTTCTAGTTCTGGGTAGTATACTCCAAC TCTAGAGAACTGAGAACTCGCTTTCCTTCTTCCAAACAAATCCCAGTAATGTTTCCAAAGGTCTGAGTTA TCCAGGAAATCTTTGCCCGGAGGTGAGAAAGGGTGGTTGATCTGACTGACAGGGGACTGAAGTATTTAAT GAATCTGAATAGGTTGTTTTCTGACTTATAGATGCAGGCTGAACTGGTGGCAAAACCCTCCGTGTCTGTG GAGTTTGTGACAAATATGGGCATCATCATTCCGGACTTCGCTAGGAGTGGGGTCCAGATGAACACCAACT TCTTCCACGAGTCGGGTCTGGAGGCTCATGTTGCCCTAAAAGCTGGGAAGCTGAAGTTTATCATTCCTTC CCCAAAGAGACCAGTCAAGCTGCTCAGTGGAGGGTAATTCTTTCAGCCAAGTCTGCCTAGCCAGTTTGAA AGAGAGAACAGAGAATGTACCTGCAGAATTTTGCCAGGCTAAACAGTTGATTGAGATCATTCAGGTCCTG AGGAAGCAGGAGAGGAGTAGAAAGGAAAGATTCCGGGTTACCTATTTTAATTCTAGCCTAGACTTACTAC ATAACTACATAATTACCTTTCTTCTACTTTTCACATTTTACTAAACTGTCCTTTATCTTTCTGCTTTGAG ACTTATTAAGACCTACTGCTTAATTAGTTTTTATTAAGTTGTGATTTTTTGTTATCTATTTGTTTTGAGA ATGAAGAAACAATAGCTCTGGAGAGATCATCTTTGGAAAATTAATATTTTCCCCCCCAAAAAATACCTAA GAACATATTGATTTGAGGTAGCTAGGTAGGTAAAGCATGAAACTCCTAACCTCGTGATAATGGAATACAG CCTCTTTTGGAGAGTTCCATTTTAAGTGGCACCCTCAACCATTGATTTGCCTTAGTTTTCATATTTTAGA CACATTCATGTGTTCATTCAAAAATAATATTTAATTGGCCAGCCACGGTGGTTCATGCCTGTAATCCTAG CACTTTGGGAGCCCCAGGTGGATGGATCGCTTGAGCCCTGGTGTTTGGATACCAGCCTGGGCAACATGGC AAAACCCCATCTCTACAAAAAAAATTAAATAAATAACAAAATTAGCCAGTCGTGGTGGCACATGCCTGTA GCTCCAGCTACTCAGAAGGCTGAGATGGGAGGATCAACTGAGCCCAAGAGTTCAAGCCTTCAGTGAACCA TGCTTGCACCACTGCACTCCAGCCTGGGAGACAGAGCAAGATCCTGTCTCACAAAAAACAAAAAATAGTA TATTTAATTGCCTAATATATACCACGTATGTTGAGTGAGACACACAAGGTCCCTGACCTTTGAACGCTTA CATTTTATAAGGGAGACACACAATTAAGCAAGCAGTAATCATAGAGTAAGGGCTAAGTTATAGAAAGTAT TAGAGTACCATGAAATTTTATATCATGTAGCCTGTGCTAGTCAGGGAATGCATTCTGAAGCAAGTGTACT TGACCTGATAACTGAGGACTGTGTCAGAGTCATTTAGGCAAAGGAGAAAGGAGTGAGTGTTCCAGGCAAA AGGAAAAGCATGTAATGGCCTGAAGGTAAAGGAATATGGTTCAAGGAACTGGAAGAAGTGCAGAATGGTA AGGGGCTCAGAGATGATGGGGAGAGGTAGGCAGGGGAGAGAGCATGCCCAGCTGCGAAAGCCATCCTAAG GAGTTTGGACTCTTTTGAAGGCACAGGAGTTGAAAAGGGGAGCAGAAATAAGATAGGGGTGATGTTTTAG AAGAAATACTCTGACTCTAGTGTGGAAGATGGGTGAGAAGGAGGCACAGCTGGACACGAAGAGACCATTG GACATCTCTTACGATCCTATGTGGCTAAGAGCTGATAATGGCCTGCAGTGGAGAAAAGCCAGGTATAGAA AGGAGTGAGCAGATTCTACAACTTTCTAAGAGGCAGAATCATAAGTACTGGGTGATTAACTGGGTATGGG GACAAGGCAAAAGAAAGAAGAAAAGAGGAAGGAGGCGCCCTTCATTTTAATAAGAACTACAGTGGGAGAG CTTCTGGTTTCAAGGAAAGTGACAAATTCAGTTTTGGATGTGCTGTATTTGATGTCCTCCTATGAAACAA CCAGTTTAGAAATCTAGCTGTCAAATAGACCTATGGATCTGAGCCCAGTAAAGAGGCTTGGGCTCCACAT ATGGATTTGGGAATCATTAGTATACAGAGGTTGTTGTGGTTAAACAGCAACTGGTATAGAGTGAGACATG AGAGATGAGGACAGAAATATGGAGAAGACAAACATATAAAGGAAGAAGGGGAATAACCAGCAATGAGTTA GAAGAAGTGACCAGAGAAGCAGAAGGAGAACCAAAGCCATAAAAGGTCACAGAAGCCAAAGAGCAGCCAC AGGGGAGATCACCCCATGGGTAGGCGAAAGCTGGCATTAGGACTCCAGCACATCAGCAAAGCTTGGTCTT GTGGCACCCCCAACTTGGAGAAACAATACTTGGAGGAAAATGTGCTATTTCAAAGAAAGCATCCTTAGAA AAAACCAGGCCAATGTTGAACTTTCTTACATGTACTAAGTTTTTAAGTACACACTTGGAAGGAAGGTGCC ATCATCTCTTCAGATGTGAGAGGCTCCAGCGTCTTAGTCTGGTCATGAGTGCGCAACTCTATGGAAGGCT TCTGGGAGGTCAAGGAAGATGAAACCTAAATATGCCCATTGGATGTAGGAGCAAGGAGGGCATTAGAGAC ATTGATGAAAGCATTTTCAGGAGATGGAGTGAGCAGTCAGAGCACATTGGGAGGAAGTAGAGACTGCAAA GGCAGACAACTCTTGATGGTGAGGAAGATGAGAAAGCAAGAAAAGAAAGAAAGGAGCATAGGGGAGGGGC ACAGGGGAAGAGACTTGAGCGTGCTTAATGCAGGTGGAAGGAAGCAGGTAGAGAGTAGGAGATTTCATAT GAAAGAGACAGTTTCTCTTGCCCTGCATTGTAGGAAGGAAGGGGCACACTGAAGTTCAGCCCCAGTGATC AGCTATTTAACATCTCTGAGCCTCTGCTTCTGTAAAATGAGAACCATAAGCCTACTGTTGTGGGGATTAC AGGTAACAGATGGAAAGAACTCAGCCAGAAGCTTCAGAGTCACTCTCATGGCTTGTCATGTTGATGTTCT TTCTAATATTATTTGTTTCTCAGTAAATTAAATAGTTAGAGATAGGTGTGGACTGAGGGAAGACAGGAGG ATAAGGGGGTATTTGCACCCTGAGAATTTGTGATGTCCATTTTGATTCATGACTTGGCAATAACTCAGGT ATTTTTGTTCTTCACCAGCAACACATTACATTTGGTCTCTACCACCAAAACGGAGGTGATCCCACCTCTC ATTGAGAACAGGCAGTCCTGGTCAGTTTGCAAGCAAGTCTTTCCTGGCCTGAATTACTGCACCTCAGGCG CTTACTCCAACGCCAGCTCCACAGACTCCGCCTCCTACTATCCGCTGACCGGGGACACCAGGTTAGAGAT GCTCAGTGCCTGACCCAGCATTTTCTCACCTTCCACATCATGGCCACCTAGCATGGCACAGGAAAAAATA CTCTGTGTTGTAAGACCCTGTCACTAGCCTTCTGGGTTTGCACCATCTTTGGGTATTTAAAGCAGGGTCC TCTGGCCAACACATTGGGTGTCACCTTTTGCTTCCTTGTGCATGGGATGGGATCACAGCACAGATCCCAA TTTGCTCCTAATTCAGTGTCCATGTTTCTGAGCCTCCAGACCCATCGCTATGAGCTTCCTGGAGCCCACC AATGTGCTTGAAGCCTTCACCGTACTTAGGTGGCTCCCTGTCTTCAGCCCCCAAGTTCCAGTGCTTGTTC TCAGCTTTGCTGAAACAACCAGCCAACTCCTGCTCTGCTTGTCCAAAGTCTTGGGAATCCTGGTGTCTGC CCTTGCCTTGGGTTCTTGTAGGACTGAGGGATCAAAAAGATCATCTTAGTTAAGGGCAAGAGACAATGTT AAAATAAGGACCATATTTTTGTTGCATTTGAGGCTGAATTGTTTTGGGAACATAATCACCATCCTTGAAA GCTCTAACATTATGCACTGTCTTCATTGTAATGTCTTTAGATTAGAGCTGGAACTGAGGCCTACAGGAGA GATTGAGCAGTATTCTGTCAGCGCAACCTATGAGCTCCAGAGAGAGGACAGAGCCTTGGTGGATACCCTG AAGTTTGTAACTCAAGCAGAAGGTGAGTATTCAAAACACAGCTGCCTCATCTCTGCTCGCAGTCTCAGGT TCAGAATTCATGAGGAGAAGACATGTAATTTAACCTATTTAACAAATAGGTTAACTGAGTACCCACTAAG CGGCAGGCCTATTCTAAGACCTGGGTTAACTGAGTACCCAATAAGCGGCAGGCCTATTCTAAGACCTGGG GCTAGAACAGTGAACAATGGAGTCTCTGCCTTCATGGAAGTTACAGTGAACAACCAAACAAGTTAATATT TGGAATATCAGATAAGTACTGAGGAGGAAAACAGAGCGTAGACTGGTCTATGGAGGGCTAGGAGTAGGAG GGAGGAAGAAGGGCAGGGAAAGCAGTGCATTTGGAATAATAAGGGAAAGTCTCCCTGGTAAAGTGAGCAT AAGGAGACCTATCAGAAATAAGAGGAGAAGCCGTGTGGTAAGACTGTTAACAGGCAGAGGGACCAGCAAG TGCAAAGGCCCTGAGGCTGACACACTACTACCATGTTTCAAGGAAAGGAAGGAAGACAGTATGGCTGGAG CAGAAAGACCAGGGAGAAAAGAGGTAGAAGATGAGGACAGAGAGATATGGAGAGGTGAAGGAAGGATAAT CTCATAGGCCATGGTAAGAACTTTGGCTTTTTCTATGAATTAAACGAAAGCCATTGGGGAGTCCTCATGA TTTGATTTATGTTTATGTTGAGAAAAGACTATGGGCAGACAAGGGCAGAGAAACTAATATGTAGGTTATC ACAATAATCCAGGCAGGAATCAGTGTTGTTTTGGATCAGGGCAATGGCAGAAGAGATATGAGAAGGGGAT GGATTCTGGCCATATTTTGAAGATTAGGCTGACAAGATTTGCTGATACAGTGGATGTTGAGTGTAAGAGG AAAAGGGGAATGAAGACAAACCTAAGGTTTTTGGCCCGGGCAACTGAAAAATGGAACTTCCATTTATTGA GATGGAAAGGGCTACTGGAGGAGCAGGTTTTAGGGAATGGGAGAAATTTAGGTGTTCACTTTGGAAAAAA AATTATATAGGGATAGCGAGGAGCAGGTTTTAGGGAATGGGGCACATTTAGGTGTTCACTTTGGAAAAAT TTTTATATAGGGATAGCATATCACAGAATTAAACTAGGAAGAAAATCCCATGATAGAAAGCACTGGAGGA GCAGGGCACGCTGGGGAAATAGTGTTTGGTAAACATTGTTTTACGAAGGATATAAAATGGACCAGCCTAT GGATTGAAGGACGCCCGGGAATCTTGTTACAAAGAAAGGGGGAGTTGGGGAGATGGAGCCCAGGGCAAGG GCAGCAAGGAACCAGGACAGGCATCTTGGGTAGAAAGTAATATAGAGATGTCGTGTCTTCCTGGCCCAGA AGGGCTGCGAGCCTTTGCTGTTCCACAAACAAGCTAAGTGCTCCCCATTTCAGGGCCTTTGCATTCCTGA CCTTCTGCCTGGAATGTGCTCCTCCCAGAACTCAGCGTGGCTCCAACCTCTTTTCATTCTGGTCTCTGCC CACATGTGCCCTTATCAGAGAGAATTTCTCTGACCACCAAGTATGAAATAACACTTCTTCTATCCCTTTC TTTTATCCTTGTATCCAGTTTTACTCTTCTTCATAACATTCATTACCATCTGACATGAGCAAGTTACTTG TTTATTGCCTGTACACCTCCCCCACTAGAAGGTAAGCCCCATGAAAGCAAGGATTCCCCAGTACCAAGAG CAGTGCCCAGCACACAATAGGCTCATAACAGGCAATCCATAAAGACTTGCATACATGAACACAACTGAGT TTAAAATTATCAGTAAATGAGACCCATTAAAAAATTTTAATGAGAAAAAAAAAATTCAGTAAAATCCTGA ACTGTGTTTTTGTTTAAGCACATTGATTCCTTGGAGTTTCTCTACCTTTTCCTCTCTTTCCTTCCAAAAC ATAGCTTCTTTATTTATTTATTTATTTATTTGTTTGTTTATTTATTTATTTATTTATTTATTTATTTTTT GAGATGGAGTCTCGCTCTTTTGCCCAGGCTGCAGTGCAGTGGTGCCATCTCGGCTCACTGCAAGCCCCGC CTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACCCACCAACGCG CCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGAATGGTCTTGATCTCC TGACCTCATGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCCGGC CCAAAACATAGCTTCTTACCACACATCTCTTGATTCTCTTATACACTCGTCCAGGTGCGAAGCAGACTGA GGCTACCATGACATTCAAATATAATCGGCAGAGTATGACCTTGTCCAGTGAAGTCCAAATTCCGGATTTT GATGTTGACCTCGGAACAATCCTCAGAGTTAATGATGAATCTACTGAGGGCAAAACGTCTTACAGACTCA CCCTGGACATTCAGAACAAGAAAATTACTGAGGTCGCCCTCATGGGCCACCTAAGGTAAAGAAGGCCGAG GGTCATCTGACCTGCACTGCAGGCCTGGGTGGTTCTTTTCATTATTCCTCTTCCACTTCATACCTGACCA AGCCATGTTCTCCCCTAGTCTACAATCAGAGTGGCAGAGAGAGCCCTCAACAATTTTTTTTTTTTTTGAG ATGGAGTCTCACTCTGTCACCAGGCTGGAGTGCAGTGGCACAATCTCGGCTCACTGCAACCTCCGCCTCC CGAGTTCAAGTGATTCTCCTGCTTAAGCCTCCCAAGGAGCTGGAACTATAGGTGCATGCCACCACACCCA GCTAATTTTTATATTTTTAGTAGAGACAGGGTTTCACCATATTGACCAGGATGGTCTCGATCTCCTGACC TCGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTAAGCCACTGCACCCGGCCAAGC TCTCAACATTTTAACCCTCTGCGCATGTCCAGTTGGATTTTCCTACCATTTATCAGGCACTTACTATTCA TGTATCAAGCACAGTGCTGGGTGCTTTAAAGAAATTATCTCGGTCCTCACAATAAACTGCGAGGTCACTG TGAGTTTTCCTGTTTCATGGATAAGGAAATGGTAGCTCAGAGGGGTTAAATCATTTGGTCAAAATCACAG AGCTAGTAAATAGCAGAGCAGGATTCAAACAGTTTTCAAAAAACTTCTCTTTCTCCTAAACCTGTTTGCA AAGTCCTTAATTTGTGCTGAATGTTGGCTTTAGAAGTTGATGAGTTTGATCTGTGGCTGTTTCTCTGAAC CATCCTTGTATCTGGTTTTGATCACCACAAATGGAACTTCTGTTTAATCCTGCATATCTCCATTGAAAGG ACAAAATCATTGGTGCCAACTGATTTTCTTTACCATAGTTGTGACACAAAGGAAGAAAGAAAAATCAAGG GTGTTATTTCCATACCCCGTTTGCAAGCAGAAGCCAGAAGTGAGATCCTCGCCCACTGGTCGCCTGCCAA ACTGCTTCTCCAAATGGACTCATCTGCTACAGCTTATGGCTCCACAGTTTCCAAGAGGGTGGCATGGCAT TATGGTATGTGTCTCTTCCCCTGTGTGAGCACTTCCAAAGTAATGCAGGTGTTGAGACCTGTGGTTACAG GCTGAACTAGTACCATTCACAACTATTTCCTACGTATTTTCAGATGAAGAGAAGATTGAATTTGAATGGA ACACAGGCACCAATGTAGATACCAAAAAAATGACTTCCAATTTCCCTGTGGATCTCTCCGATTATCCTAA GAGCTTGCATATGTATGCTAATAGACTCCTGGATCACAGAGTCCCTCAAACAGACATGACTTTCCGGCAC GTGGGTTCCAAATTAATAGTTGTAAGTATGAGTCTGCCAGTCAATAAATACATGGATATAAGTGCTAATT ACATCCTCAACTCTGAGCTAGGTGCAGGAAGGTTTCCAAAGATGTATAAGGCATGCTTCCTTCCCCCCAG GGAATTCTTGGGGAGAAAAAAAAACTTTCACAAGTGTGTAGTTACCCAGTTACACAAAGCTGAATGTGAT ACATATCAAAGAGATGCTACTAAGTAGAACAGTTCTTTGCCTAGTGGTATCAAAGGAAGCTTCAGGACAC CAGCTAGGAGGCTGACTATGTTAGACATTCCTTTTATAAATATGGACAGTGATCAGTGACTGGCAACGAA GATTCATAATTTTCTGTTATTTATTTTTAACTTTCAGTGCATTGTCCAGCTTAATAATTAACTTGTCAAA TCGGTATTTTTGCCTAATGTTCATTGCTCTTTGAGGCTCATCCAAGCCCATTACCTTAAAAATCTCCTGT CATTTTGTAGGCAATGAGCTCATGGCTTCAGAAGGCATCTGGGAGTCTTCCTTATACCCAGACTTTGCAA GACCACCTCAATAGCCTGAAGGAGTTCAACCTCCAGAACATGGGATTGCCAGACTTCCACATCCCAGAAA ACCTCTTCTTAAAAAGGTAAAAGAAGAAAGCAGCAAGGCTTCTTGAACCATGCAAAGTAAATGAAAGATT TTACATAGCATGATTTAGACATTTTTTTAAATTTTTAAAGGAAATAATTTAAGCATTTTAAGGAGATTAA TAACTATAGCACAAACACTGTGGCATCTTTGCATTAGTAAACATGAGAACACCAACCCTGTCAGGAAGAA TCTAAGAAAGTCATTAGAGGATTCTGGTACTTTCACCCTAAGATATTTTATTCAGTACAACCTGTTATAA GCAAATTCTCCCTCTGACTGTGAAGAATTCAGAATGGCTAGAGGCGTTATTGACTACAGGCTTGCTGTTA AGCTAGAGAGAGTCAGAACAGCCATTGAGCACTAAATGGAGGCAGCATTCTGAGAAAATACTTTAACCCA GGCTTACTGACTTCCATACCTATGTTCTTTCCACAAATCAAGTTGTCTCAATTCAGTTTAGCAAATTTGT ATCAAGTATCCCCTATGTGCAAAATGCTAGACTAGGTACAGTGAGAAGATAGAAACTGGGTAAGGTATAG CCTTTTCTTTCAAGAAGATACCATGGAGACATCAACAAATGAGAAATAATTAATTATATAAGCAAAATTA TGACATGCTCTTTGAGAAAGGTGCAAGGGACTATGTAACTGTAAGAATGAGACAAATTGGCTATGACTTA GGTGGGATGGTAATGATAAGGAGTGGCCCTTAGAAGAGCTTTGTCAGGATTTGAGTGTTTGACAGGTGGA GGTAAAAGCAAAGGGGTCCAGGCATAGGAGTAGCACAAAGAAAAGTGCAGAGTGGCTTTGGGAATGGGGC AAGTACAATATTGTTGTGAAGGTCAGAGGCAGAGAACTTTGAATGACTGATGTCTGACTGTGGGGATGTT ATCTTTGTTGTTCATTTCAGCGATGGCCGGGTCAAATATACCTTGAACAAGAACAGTTTGAAAATTGAGA TTCCTTTGCCTTTTGGTGGCAAATCCTCCAGAGATCTAAAGATGTTAGAGACTGTTAGGACACCAGCCCT CCACTTCAAGTCTGTGGGATTCCATCTGCCATCTCGAGAGTTCCAAGTCCCTACTTTTACCATTCCCAAG TTGTATCAACTGCAAGTGCCTCTCCTGGGTGTTCTAGACCTCTCCACGAATGTCTACAGCAACTTGTACA ACTGGTCCGCCTCCTACAGTGGTGGCAACACCAGCACAGACCATTTCAGCCTTCGGGCTCGTTACCACAT GAAGGCTGACTCTGTGGTTGACCTGCTTTCCTACAATGTGCAAGGTGAGCTATGCTCAGGTAAAGGGTGC ACCGGGCTAGTTCATGGCAGGCTCTAAGAGGAGAGCCTCCTCCAGGGAGGAAAGGACTTTGGCTTTCTAG CAGATAATCTTCCTTGCTACTTGGAAGTCTTTTATTTTATTCAACAAATAGAAATATTTATTAAACATAT CACGTGTATTAAATATTCTAGTAGGCAGTAACAGAAAGTAGACAGATAAGCCAGCAATTATAATTCAGTG TGAGAGGTGCTATGATAAAGTGTAGTATATAAGTATAAGGTAGAGTGGAAGCACTCAACAAGGGAACCTA AACAAAGCCTGTGGTGGTCAGGCAAGGCTTCCTGGAGGAATGCCTTTTGCTATCAGATTTTATCTTTGCA TTACAGATGGAGGAGTCTATTGCACAATTGGCCCAGAAAAATGGGGCTTTATTATTGAAAGACTTTCAAC ATAGAGATTGCTCTGGAAATGTACTGCTTAATTTAACCAATGTCTTTTCATTTTTATGTTAGGATCTGGA GAAACAACATATGACCACAAGAATACGTTCACACTATCATGTGATGGGTCTCTACGCCACAAATTTCTAG ATTCGAATATCAAATTCAGTCATGTAGAAAAACTTGGAAACAACCCAGTCTCAAAAGGTTTACTAATATT CGATGCATCTAGTTCCTGGGGACCACAGATGTCTGCTTCAGTTCATTTGGACTCCAAAAAGAAACAGCAT TTGTTTGTCAAAGAAGTCAAGATTGATGGGCAGTTCAGAGTCTCTTCGTTCTATGCTAAAGGCACATATG GCCTGTCTTGTCAGAGGGATCCTAACACTGGCCGGCTCAATGGAGAGTCCAACCTGAGGTTTAACTCCTC CTACCTCCAAGGCACCAACCAGATAACAGGAAGATATGAAGATGGAACCCTCTCCCTCACCTCCACCTCT GATCTGCAAAGTGGCATCATTAAAAATACTGCTTCCCTAAAGTATGAGAACTACGAGCTGACTTTAAAAT CTGACACCAATGGGAAGTATAAGAACTTTGCCACTTCTAACAAGATGGATATGACCTTCTCTAAGCAAAA TGCACTGCTGCGTTCTGAATATCAGGCTGATTACGAGTCATTGAGGTTCTTCAGCCTGCTTTCTGGATCA CTAAATTCCCATGGTCTTGAGTTAAATGCTGACATCTTAGGCACTGACAAAATTAATAGTGGTGCTCACA AGGCGACACTAAGGATTGGCCAAGATGGAATATCTACCAGTGCAACGACCAACTTGAAGTGTAGTCTCCT GGTGCTGGAGAATGAGCTGAATGCAGAGCTTGGCCTCTCTGGGGCATCTATGAAATTAACAACAAATGGC CGCTTCAGGGAACACAATGCAAAATTCAGTCTGGATGGGAAAGCCGCCCTCACAGAGCTATCACTGGGAA GTGCTTATCAGGCCATGATTCTGGGTGTCGACAGCAAAAACATTTTCAACTTCAAGGTCAGTCAAGAAGG ACTTAAGCTCTCAAATGACATGATGGGCTCATATGCTGAAATGAAATTTGACCACACAAACAGTCTGAAC ATTGCAGGCTTATCACTGGACTTCTCTTCAAAACTTGACAACATTTACAGCTCTGACAAGTTTTATAAGC AAACTGTTAATTTACAGCTACAGCCCTATTCTCTGGTAACTACTTTAAACAGTGACCTGAAATACAATGC TCTGGATCTCACCAACAATGGGAAACTACGGCTAGAACCCCTGAAGCTGCATGTGGCTGGTAACCTAAAA GGAGCCTACCAAAATAATGAAATAAAACACATCTATGCCATCTCTTCTGCTGCCTTATCAGCAAGCTATA AAGCAGACACTGTTGCTAAGGTTCAGGGTGTGGAGTTTAGCCATCGGCTCAACACAGACATCGCTGGGCT GGCTTCAGCCATTGACATGAGCACAAACTATAATTCAGACTCACTGCATTTCAGCAATGTCTTCCGTTCT GTAATGGCCCCGTTTACCATGACCATCGATGCACATACAAATGGCAATGGGAAACTCGCTCTCTGGGGAG AACATACTGGGCAGCTGTATAGCAAATTCCTGTTGAAAGCAGAACCTCTGGCATTTACTTTCTCTCATGA TTACAAAGGCTCCACAAGTCATCATCTCGTGTCTAGGAAAAGCATCAGTGCAGCTCTTGAACACAAAGTC AGTGCCCTGCTTACTCCAGCTGAGCAGACAGGCACCTGGAAACTCAAGACCCAATTTAACAACAATGAAT ACAGCCAGGACTTGGATGCTTACAACACTAAAGATAAAATTGGCGTGGAGCTTACTGGACGAACTCTGGC TGACCTAACTCTACTAGACTCCCCAATTAAAGTGCCACTTTTACTCAGTGAGCCCATCAATATCATTGAT GCTTTAGAGATGAGAGATGCCGTTGAGAAGCCCCAAGAATTTACAATTGTTGCTTTTGTAAAGTATGATA AAAACCAAGATGTTCACTCCATTAACCTCCCATTTTTTGAGACCTTGCAAGAATATTTTGAGAGGAATCG ACAAACCATTATAGTTGTACTGGAAAACGTACAGAGAAACCTGAAGCACATCAATATTGATCAATTTGTA AGAAAATACAGAGCAGCCCTGGGAAAACTCCCACAGCAAGCTAATGATTATCTGAATTCATTCAATTGGG AGAGACAAGTTTCACATGCCAAGGAGAAACTGACTGCTCTCACAAAAAAGTATAGAATTACAGAAAATGA TATACAAATTGCATTAGATGATGCCAAAATCAACTTTAATGAAAAACTATCTCAACTGCAGACATATATG ATACAATTTGATCAGTATATTAAAGATAGTTATGATTTACATGATTTGAAAATAGCTATTGCTAATATTA TTGATGAAATCATTGAAAAATTAAAAAGTCTTGATGAGCACTATCATATCCGTGTAAATTTAGTAAAAAC AATCCATGATCTACATTTGTTTATTGAAAATATTGATTTTAACAAAAGTGGAAGTAGTACTGCATCCTGG ATTCAAAATGTGGATACTAAGTACCAAATCAGAATCCAGATACAAGAAAAACTGCAGCAGCTTAAGAGAC ACATACAGAATATAGACATCCAGCACCTAGCTGGAAAGTTAAAACAACACATTGAGGCTATTGATGTTAG AGTGCTTTTAGATCAATTGGGAACTACAATTTCATTTGAAAGAATAAATGACATTCTTGAGCATGTCAAA CACTTTGTTATAAATCTTATTGGGGATTTTGAAGTAGCTGAGAAAATCAATGCCTTCAGAGCCAAAGTCC ATGAGTTAATCGAGAGGTATGAAGTAGACCAACAAATCCAGGTTTTAATGGATAAATTAGTAGAGTTGGC CCACCAATACAAGTTGAAGGAGACTATTCAGAAGCTAAGCAATGTCCTACAACAAGTTAAGATAAAAGAT TACTTTGAGAAATTGGTTGGATTTATTGATGATGCTGTCAAGAAGCTTAATGAATTATCTTTTAAAACAT TCATTGAAGATGTTAACAAATTCCTTGACATGTTGATAAAGAAATTAAAGTCATTTGATTACCACCAGTT TGTAGATGAAACCAATGACAAAATCCGTGAGGTGACTCAGAGACTCAATGGTGAAATTCAGGCTCTGGAA CTACCACAAAAAGCTGAAGCATTAAAACTGTTTTTAGAGGAAACCAAGGCCACAGTTGCAGTGTATCTGG AAAGCCTACAGGACACCAAAATAACCTTAATCATCAATTGGTTACAGGAGGCTTTAAGTTCAGCATCTTT GGCTCACATGAAGGCCAAATTCCGAGAGACCCTAGAAGATACACGAGACCGAATGTATCAAATGGACATT CAGCAGGAACTTCAACGATACCTGTCTCTGGTAGGCCAGGTTTATAGCACACTTGTCACCTACATTTCTG ATTGGTGGACTCTTGCTGCTAAGAACCTTACTGACTTTGCAGAGCAATATTCTATCCAAGATTGGGCTAA ACGTATGAAAGCATTGGTAGAGCAAGGGTTCACTGTTCCTGAAATCAAGACCATCCTTGGGACCATGCCT GCCTTTGAAGTCAGTCTTCAGGCTCTTCAGAAAGCTACCTTCCAGACACCTGATTTTATAGTCCCCCTAA CAGATTTGAGGATTCCATCAGTTCAGATAAACTTCAAAGACTTAAAAAATATAAAAATCCCATCCAGGTT TTCCACACCAGAATTTACCATCCTTAACACCTTCCACATTCCTTCCTTTACAATTGACTTTGTAGAAATG AAAGTAAAGATCATCAGAACCATTGACCAGATGCTGAACAGTGAGCTGCAGTGGCCCGTTCCAGATATAT ATCTCAGGGATCTGAAGGTGGAGGACATTCCTCTAGCGAGAATCACCCTGCCAGACTTCCGTTTACCAGA AATCGCAATTCCAGAATTCATAATCCCAACTCTCAACCTTAATGATTTTCAAGTTCCTGACCTTCACATA CCAGAATTCCAGCTTCCCCACATCTCACACACAATTGAAGTACCTACTTTTGGCAAGCTATACAGTATTC TGAAAATCCAATCTCCTCTTTTCACATTAGATGCAAATGCTGACATAGGGAATGGAACCACCTCAGCAAA CGAAGCAGGTATCGCAGCTTCCATCACTGCCAAAGGAGAGTCCAAATTAGAAGTTCTCAATTTTGATTTT CAAGCAAATGCACAACTCTCAAACCCTAAGATTAATCCGCTGGCTCTGAAGGAGTCAGTGAAGTTCTCCA GCAAGTACCTGAGAACGGAGCATGGGAGTGAAATGCTGTTTTTTGGAAATGCTATTGAGGGAAAATCAAA CACAGTGGCAAGTTTACACACAGAAAAAAATACACTGGAGCTTAGTAATGGAGTGATTGTCAAGATAAAC AATCAGCTTACCCTGGATAGCAACACTAAATACTTCCACAAATTGAACATCCCCAAACTGGACTTCTCTA GTCAGGCTGACCTGCGCAACGAGATCAAGACACTGTTGAAAGCTGGCCACATAGCATGGACTTCTTCTGG AAAAGGGTCATGGAAATGGGCCTGCCCCAGATTCTCAGATGAGGGAACACATGAATCACAAATTAGTTTC ACCATAGAAGGACCCCTCACTTCCTTTGGACTGTCCAATAAGATCAATAGCAAACACCTAAGAGTAAACC AAAACTTGGTTTATGAATCTGGCTCCCTCAACTTTTCTAAACTTGAAATTCAATCACAAGTCGATTCCCA GCATGTGGGCCACAGTGTTCTAACTGCTAAAGGCATGGCACTGTTTGGAGAAGGGAAGGCAGAGTTTACT GGGAGGCATGATGCTCATTTAAATGGAAAGGTTATTGGAACTTTGAAAAATTCTCTTTTCTTTTCAGCCC AGCCATTTGAGATCACGGCATCCACAAACAATGAAGGGAATTTGAAAGTTCGTTTTCCATTAAGGTTAAC AGGGAAGATAGACTTCCTGAATAACTATGCACTGTTTCTGAGTCCCAGTGCCCAGCAAGCAAGTTGGCAA GTAAGTGCTAGGTTCAATCAGTATAAGTACAACCAAAATTTCTCTGCTGGAAACAACGAGAACATTATGG AGGCCCATGTAGGAATAAATGGAGAAGCAAATCTGGATTTCTTAAACATTCCTTTAACAATTCCTGAAAT GCGTCTACCTTACACAATAATCACAACTCCTCCACTGAAAGATTTCTCTCTATGGGAAAAAACAGGCTTG AAGGAATTCTTGAAAACGACAAAGCAATCATTTGATTTAAGTGTAAAAGCTCAGTATAAGAAAAACAAAC ACAGGCATTCCATCACAAATCCTTTGGCTGTGCTTTGTGAGTTTATCAGTCAGAGCATCAAATCCTTTGA CAGGCATTTTGAAAAAAACAGAAACAATGCATTAGATTTTGTCACCAAATCCTATAATGAAACAAAAATT AAGTTTGATAAGTACAAAGCTGAAAAATCTCACGACGAGCTCCCCAGGACCTTTCAAATTCCTGGATACA CTGTTCCAGTTGTCAATGTTGAAGTGTCTCCATTCACCATAGAGATGTCGGCATTCGGCTATGTGTTCCC AAAAGCAGTCAGCATGCCTAGTTTCTCCATCCTAGGTTCTGACGTCCGTGTGCCTTCATACACATTAATC CTGCCATCATTAGAGCTGCCAGTCCTTCATGTCCCTAGAAATCTCAAGCTTTCTCTTCCAGATTTCAAGG AATTGTGTACCATAAGCCATATTTTTATTCCTGCCATGGGCAATATTACCTATGATTTCTCCTTTAAATC AAGTGTCATCACACTGAATACCAATGCTGAACTTTTTAACCAGTCAGATATTGTTGCTCATCTCCTTTCT TCATCTTCATCTGTCATTGATGCACTGCAGTACAAATTAGAGGGCACCACAAGATTGACAAGAAAAAGGG GATTGAAGTTAGCCACAGCTCTGTCTCTGAGCAACAAATTTGTGGAGGGTAGTCATAACAGTACTGTGAG CTTAACCACGAAAAATATGGAAGTGTCAGTGGCAACAACCACAAAAGCCCAAATTCCAATTTTGAGAATG AATTTCAAGCAAGAACTTAATGGAAATACCAAGTCAAAACCTACTGTCTCTTCCTCCATGGAATTTAAGT ATGATTTCAATTCTTCAATGCTGTACTCTACCGCTAAAGGAGCAGTTGACCACAAGCTTAGCTTGGAAAG CCTCACCTCTTACTTTTCCATTGAGTCATCTACCAAAGGAGATGTCAAGGGTTCGGTTCTTTCTCGGGAA TATTCAGGAACTATTGCTAGTGAGGCCAACACTTACTTGAATTCCAAGAGCACACGGTCTTCAGTGAAGC TGCAGGGCACTTCCAAAATTGATGATATCTGGAACCTTGAAGTAAAAGAAAATTTTGCTGGAGAAGCCAC ACTCCAACGCATATATTCCCTCTGGGAGCACAGTACGAAAAACCACTTACAGCTAGAGGGCCTCTTTTTC ACCAACGGAGAACATACAAGCAAAGCCACCCTGGAACTCTCTCCATGGCAAATGTCAGCTCTTGTTCAGG TCCATGCAAGTCAGCCCAGTTCCTTCCATGATTTCCCTGACCTTGGCCAGGAAGTGGCCCTGAATGCTAA CACTAAGAACCAGAAGATCAGATGGAAAAATGAAGTCCGGATTCATTCTGGGTCTTTCCAGAGCCAGGTC GAGCTTTCCAATGACCAAGAAAAGGCACACCTTGACATTGCAGGATCCTTAGAAGGACACCTAAGGTTCC TCAAAAATATCATCCTACCAGTCTATGACAAGAGCTTATGGGATTTCCTAAAGCTGGATGTAACCACCAG CATTGGTAGGAGACAGCATCTTCGTGTTTCAACTGCCTTTGTGTACACCAAAAACCCCAATGGCTATTCA TTCTCCATCCCTGTAAAAGTTTTGGCTGATAAATTCATTATTCCTGGGCTGAAACTAAATGATCTAAATT CAGTTCTTGTCATGCCTACGTTCCATGTCCCATTTACAGATCTTCAGGTTCCATCGTGCAAACTTGACTT CAGAGAAATACAAATCTATAAGAAGCTGAGAACTTCATCATTTGCCCTCAACCTACCAACACTCCCCGAG GTAAAATTCCCTGAAGTTGATGTGTTAACAAAATATTCTCAACCAGAAGACTCCTTGATTCCCTTTTTTG AGATAACCGTGCCTGAATCTCAGTTAACTGTGTCCCAGTTCACGCTTCCAAAAAGTGTTTCAGATGGCAT TGCTGCTTTGGATCTAAATGCAGTAGCCAACAAGATCGCAGACTTTGAGTTGCCCACCATCATCGTGCCT GAGCAGACCATTGAGATTCCCTCCATTAAGTTCTCTGTACCTGCTGGAATTGTCATTCCTTCCTTTCAAG CACTGACTGCACGCTTTGAGGTAGACTCTCCCGTGTATAATGCCACTTGGAGTGCCAGTTTGAAAAACAA AGCAGATTATGTTGAAACAGTCCTGGATTCCACATGCAGCTCAACCGTACAGTTCCTAGAATATGAACTA AATGGTAAGAAATATCCTGCCTCCTCTCCTAGATACTGTATATTTTCAATGAGAGTTATGAGTAAATAAT TATGTATTTAGTTGTGAGTAGATGTACAATTACTCAATGTCACAAAATTTTAAGTAAGAAAAGAGATACA TGTATACCCTACACGTAAAAACCAAACTGTAGAAAATCTAGTGTCATTCAAGACAAACAGCTTTAAAGAA AATGGATTTTTCTGTAATTATTTTAGGACTAACAATGTCTTTTAACTATTTATTTTAAAATAAGTGTGAG CTGTACATTGCATATTTTAAACACAAGTGAAATATCTGGTTAGGATAGAATTCTCCCAGTTTTCACAATG AAAACATCAACGTCCTACTGTTATGAATCTAATAAAATACAAAATCTCTCCTATACAGTTTTGGGAACAC ACAAAATCGAAGATGGTACGTTAGCCTCTAAGACTAAAGGAACATTTGCACACCGTGACTTCAGTGCAGA ATATGAAGAAGATGGCAAATATGAAGGACTTCAGTATGGAGCTTTTATTGAATTGAAACCTTATACCTTT TGAAAACTCATTGTGATTTTCTTCATCTCCATACCCCTTTCGTGATAGCTCATCTGTTTTTCTGCTTTCA GGGAATGGGAAGGAAAAGCGCACCTCAATATCAAAAGCCCAGCGTTCACCGATCTCCATCTGCGCTACCA GAAAGACAAGAAAGGCATCTCCACCTCAGCAGCCTCCCCAGCCGTAGGCACCGTGGGCATGGATATGGAT GAAGATGACGACTTTTCTAAATGGAACTTCTACTACAGCCCTCAGGTAAATACCACCTAATGAGTGACAC GCCCCCAAGAGCGAGTGGAGAATTGGGGCAGATACATTTAATTCAGGACCAAATATTCAGAGATTCCCCA AACTAGGTGAAAGACAGGCGGTAAGCAACTTCTTCTCTGAGGAAATATTCTCTAGAAAGTATTACAATGA GTCCTTGATTGATTTTAATGTTTAGATGCACACATGACATCCCATCAGCACTATTATTTATTAATTCTGG GCAAATCCAGGAAGATGAGGGTTATACCTCATCATCTAAATCATAGGCAAGCTCAGCCATAGGCAGGGTA TATTTTTCAGAGAGGACTGGTTTCTGTAGTATTTAAAACTTTAAAATTCTTCCCCACAATAGAATTGCTA GATGAGATACATCAAATTCCTCTCATGTCATTTACAAGCTCTGCCAGGGCCAAATCAAGGGTGACATTAC CAGAGGAGAAGACCAAACATGGTTCTATGACTGTTACTAAAAGTTTGTCATGGGCTTGGAGAATGCGTAC TGATGTTGGGATTCTGGGTCTCTGCAGGGTGGGCTCCAACTTGCCTTTTTTGCTATTTCTTCTTTTCCTA TCTGTCATTTCCTGACTCTTCTTCTCTCTCCTCTTCTTTCTCTTCCCCCCACTCCTCTTCCAGTTTTCAG TCCTAGGAAGGCTTTAATTTTAAGTGTCACAATGTAAATGACAAACAGCAAGCGTTTTTGTTAAATCCTT TCTGGGGCATGTGATAAAGAGAAATTAACAACAGTAGACTTATTTAACCATAAAACAAACACATGAACTG ACATATGAAAGATAAATCCCTTTCAGTATATGAAAGATTCTCTGATCTTTATTTTTAACTGCTAATGAAG TTTTAGTGTACTATATTGTGTAATTGGAGTAATTGAAAACATGTTATTTTTTTTTTTCTCTCTGTTTAGT CCTCTCCAGATAAAAAACTCACCATATTCAAAACTGAGTTGAGGGTCCGGGAATCTGATGAGGAAACTCA GATCAAAGTTAATTGGGAAGAAGAGGCAGCTTCTGGCTTGCTAACCTCTCTGAAAGACAACGTGCCCAAG GCCACAGGGGTCCTTTATGATTATGTCAACAAGTACCACTGGGAACACACAGGGCTCACCCTGAGAGAAG TGTCTTCAAAGCTGAGAAGAAATCTGCAGAACAATGCTGAGTGGGTTTATCAAGGGGCCATTAGGCAAAT TGATGATATCGACGTGAGGTTCCAGAAAGCAGCCAGTGGCACCACTGGGACCTACCAAGAGTGGAAGGAC AAGGCCCAGAATCTGTACCAGGAACTGTTGACTCAGGAAGGCCAAGCCAGTTTCCAGGGACTCAAGGATA ACGTGTTTGATGGCTTGGTACGAGTTACTCAAGAATTCCATATGAAAGTCAAGCATCTGATTGACTCACT CATTGATTTTCTGAACTTCCCCAGATTCCAGTTTCCGGGGAAACCTGGGATATACACTAGGGAGGAACTT TGCACTATGTTCATAAGGGAGGTAGGGACGGTACTGTCCCAGGTATATTCGAAAGTCCATAATGGTTCAG AAATACTGTTTTCCTATTTCCAAGACCTAGTGATTACACTTCCTTTCGAGTTAAGGAAACATAAACTAAT AGATGTAATCTCGATGTATAGGGAACTGTTGAAAGATTTATCAAAAGAAGCCCAAGAGGTATTTAAAGCC ATTCAGTCTCTCAAGACCACAGAGGTGCTACGTAATCTTCAGGACCTTTTACAATTCATTTTCCAACTAA TAGAAGATAACATTAAACAGCTGAAAGAGATGAAATTTACTTATCTTATTAATTATATCCAAGATGAGAT CAACACAATCTTCAGTGATTATATCCCATATGTTTTTAAATTGTTGAAAGAAAACCTATGCCTTAATCTT CATAAGTTCAATGAATTTATTCAAAACGAGCTTCAGGAAGCTTCTCAAGAGTTACAGCAGATCCATCAAT ACATTATGGCCCTTCGTGAAGAATATTTTGATCCAAGTATAGTTGGCTGGACAGTGAAATATTATGAACT TGAAGAAAAGATAGTCAGTCTGATCAAGAACCTGTTAGTTGCTCTTAAGGACTTCCATTCTGAATATATT GTCAGTGCCTCTAACTTTACTTCCCAACTCTCAAGTCAAGTTGAGCAATTTCTGCACAGAAATATTCAGG AATATCTTAGCATCCTTACCGATCCAGATGGAAAAGGGAAAGAGAAGATTGCAGAGCTTTCTGCCACTGC TCAGGAAATAATTAAAAGCCAGGCCATTGCGACGAAGAAAATAATTTCTGATTACCACCAGCAGTTTAGA TATAAACTGCAAGATTTTTCAGACCAACTCTCTGATTACTATGAAAAATTTATTGCTGAATCCAAAAGAT TGATTGACCTGTCCATTCAAAACTACCACACATTTCTGATATACATCACGGAGTTACTGAAAAAGCTGCA ATCAACCACAGTCATGAACCCCTACATGAAGCTTGCTCCAGGAGAACTTACTATCATCCTCTAATTTTTT AAAAGAAATCTTCATTTATTCTTCTTTTCCAATTGAACTTTCACATAGCACAGAAAAAATTCAAACTGCC TATATTGATAAAACCATACAGTGAGCCAGCCTTGCAGTAGGCAGTAGACTATAAGCAGAAGCACATATGA ACTGGACCTGCACCAAAGCTGGCACCAGGGCTCGGAAGGTCTCTGAACTCAGAAGGATGGCATTTTTTGC AAGTTAAAGAAAATCAGGATCTGAGTTATTTTGCTAAACTTGGGGGAGGAGGAACAAATAAATGGAGTCT TTATTGTGTATCATACCACTGAATGTGGCTCATTTGTATTGAAAGACAGTGAAACGAGGGCATTGATAAA ATGTTCTGGCACAGCAAAACCTCTAGAACACATAGTGTGATTTAAGTAACAGAATAAAAATGGAAACGGA GAAATTATGGAGGGAAATATTTTGCAAAAATATTTAAAAAGATGAGGTAATTGTGTTTTTATAATTAAAT ATTTTATAATTAAAATATTTATAATTAAAATATTTATAATTAAATATTTTATAATTAAAATATTTATAAT TAAATATTTTATAATTAAAGTATTTATAATTAAATATTTTATAATTAAAATATTTATAATTAAATATTTT ATAATTAAAATATTTATAATTAAATATTTTATAATTAAAATATTTATAATTAAATATTTTATAATTAAAA TGTTTATAATTAAATATTTTATAATTAAAATGTTTATAATTACATATTTTATAATTAAAATGTTTATAAT TACATATTTTATAATTAAAATGTTTATAATTACATATTTTATAATTAAAATGTTTATAATTACATATTTT ATAATTAAAATGTTTATAATTACATATTTTATAATTACATATTTTATAAAGTATTTATAATTACATATTT TATAATTAAAGTATTTATAATTACATATTTTATAATTAAAGTATTTATAATTACATATTTTATAATTCAA TATTTTATAAATAGTTAAAAAGACGAGGAAAAAATTAAAAAGACGAGGTTATTGATCTCAGGAATTGTAT TTGCCAAGTGAGAAGGAAAAAATATTCACAAAGGCTTGTACATACTTTGATCCTGAGGAACACCTCTGGT GTCTTCATGTGCCACATAGTCTTCCTCACTGACTGTCTGCCTTTGCAAGGCAAGGCTCTCCGGTAGGCCT CGAGATGAAATAACAAGTCCTTTATTTCACTCAGCCTGCCAGGAGTGGAGAAGGAATGGCTAGGGAGTCC TAGCCCCAGGGGCTTCATGGCAATACGGACCCCAGATGTCTCCCTGGAGCTCTGCCAGGATCCATTCAAG GCCAAGAAAGTATGATTGGGAGAGGAGGGGTGGAGATGTAGATTCCTAACAATTCTGTGACCCAGCATAC ATGTATGCTCTTTAGGCTCTTAAGCATCCTTATTTTTCCAAATATAATATCCAACAATCCCAAGTGTAGT AAAAACCCAAGGGTTTCTCCTGCCACATCCACTCACTTCAAACTCTGATTTTAAACACTGGCAATATCCA GTCAGAGCCTCCAAGCTGAGCTCTAGAAAGAGAAAGCTGCAAAAAACCTGTGCAACAAAACTTGCACTCA TATTACTGACAAGGGTAGATATAAAACAGCGCATTCTTTTCCATGACACTGAAGAGCAAAGAAGAGTGTA ACTTGGGGGCAATAAGAAATTGGAGGTCACCACCTCCCAAATCCTACATGAGGTCTATTTGGAAAAGACC TCCTTTTTTAATTCAAAAATCCTTCAACCTCCACCATTCTTTCATAAAGCTTCACATTCTCTTGGTGAAG CCCACTGTTAAAATGCACAGGCGTTACCTGGAAAAGGAAACACATAGCCTTAACAATATTCTTCTGTACT GAACTGAAGAGTGAGAAAGAGTCTATGGAGCTATAATACGGTAGTGTATGAATCTGGTACTCAAGGAAAG TCTGTTGGATAATGGATGGATGGATGGATGGATGGATGGGTGGGTGAGCGAATAAATGAGTGGATAAATG AGGGGTCAGTTTTGAGAGTGAGAGAAACATGGAAATTAGACTCAAATCCCAAGGCACCACATGGAATAGT TCCAGGAATAGTTCTGCAAGAGTTTCCCTGATGAGCTATAAGCAGCAAAAATTTAGTGAGTGTTCAAACT GAAAGGAGGCCTGGAATTGTGGCTTAATTTGGAGGGAAAGAGGGAGTCCAAGATTCCCAGTGCTTATTTG TTGATATCTATCTAGTGCTGAAAAGAAAAAAAAATAGCCACAAATCCAAAATGATTGTGCAGTCACATGG TACCCACTGCCCAGTTCCTTGACCAGTGTCCCTCATACAAAGGGCCCCTGATGAGCTCAGAATGTCTTTG TTGTACTGAATAAAGTTTGAAGAACAAGGGATCCTTGTGGGGACTTGGACTTTGCCTGCTCCCTTCTTAG GTCTTCTACTGCATATCTGGATACTTCTCTGGTTCAATTAATAGCTACATTTTTTA Download Select all
Length	42645
OMIM ID	107730
HGNC ID	HGNC:603
Unigene ID	Hs.120759
Ensembl ID	ENSG00000084674
PharmGKB ID	PA50

mRNA Information

mRNA ID	XM_011532809.1
Exon	join(1..210,523..561,1598..1713,2991..3136,5963..6116, 6819..6974,8366..8490,9173..9258,10556..10775, 11493..11720,14059..14176,14289..14435,15536..15747, 16009..16246,17110..17286,18950..19141,20382..20549, 21032..21243,24169..24351,24961..25082,27425..27635, 28529..28704,28814..29001,29481..29626,30541..30914, 31423..33070,33337..33341,44801..44856)
mRNA Sequence	>gi\|767914429\|ref\|XM_011532809.1\| PREDICTED: Homo sapiens apolipoprotein B (APOB), transcript variant X1, mRNA ATTCCCACCGGGACCTGCGGGGCTGAGTGCCCTTCTCGGTTGCTGCCGCTGAGGAGCCCGCCCAGCCAGC CAGGGCCGCGAGGCCGAGGCCAGGCCGCAGCCCAGGAGCCGCCCCACCGCAGCTGGCGATGGACCCGCCG AGGCCCGCGCTGCTGGCGCTGCTGGCGCTGCCTGCGCTGCTGCTGCTGCTGCTGGCGGGCGCCAGGGCCG AAGAGGAAATGCTGGAAAATGTCAGCCTGGTCTGTCCAAAAGATGCGACCCGATTCAAGCACCTCCGGAA GTACACATACAACTATGAGGCTGAGAGTTCCAGTGGAGTCCCTGGGACTGCTGATTCAAGAAGTGCCACC AGGATCAACTGCAAGGTTGAGCTGGAGGTTCCCCAGCTCTGCAGCTTCATCCTGAAGACCAGCCAGTGCA CCCTGAAAGAGGTGTATGGCTTCAACCCTGAGGGCAAAGCCTTGCTGAAGAAAACCAAGAACTCTGAGGA GTTTGCTGCAGCCATGTCCAGGTATGAGCTCAAGCTGGCCATTCCAGAAGGGAAGCAGGTTTTCCTTTAC CCGGAGAAAGATGAACCTACTTACATCCTGAACATCAAGAGGGGCATCATTTCTGCCCTCCTGGTTCCCC CAGAGACAGAAGAAGCCAAGCAAGTGTTGTTTCTGGATACCGTGTATGGAAACTGCTCCACTCACTTTAC CGTCAAGACGAGGAAGGGCAATGTGGCAACAGAAATATCCACTGAAAGAGACCTGGGGCAGTGTGATCGC TTCAAGCCCATCCGCACAGGCATCAGCCCACTTGCTCTCATCAAAGGCATGACCCGCCCCTTGTCAACTC TGATCAGCAGCAGCCAGTCCTGTCAGTACACACTGGACGCTAAGAGGAAGCATGTGGCAGAAGCCATCTG CAAGGAGCAACACCTCTTCCTGCCTTTCTCCTACAAGAATAAGTATGGGATGGTAGCACAAGTGACACAG ACTTTGAAACTTGAAGACACACCAAAGATCAACAGCCGCTTCTTTGGTGAAGGTACTAAGAAGATGGGCC TCGCATTTGAGAGCACCAAATCCACATCACCTCCAAAGCAGGCCGAAGCTGTTTTGAAGACTCTCCAGGA ACTGAAAAAACTAACCATCTCTGAGCAAAATATCCAGAGAGCTAATCTCTTCAATAAGCTGGTTACTGAG CTGAGAGGCCTCAGTGATGAAGCAGTCACATCTCTCTTGCCACAGCTGATTGAGGTGTCCAGCCCCATCA CTTTACAAGCCTTGGTTCAGTGTGGACAGCCTCAGTGCTCCACTCACATCCTCCAGTGGCTGAAACGTGT GCATGCCAACCCCCTTCTGATAGATGTGGTCACCTACCTGGTGGCCCTGATCCCCGAGCCCTCAGCACAG CAGCTGCGAGAGATCTTCAACATGGCGAGGGATCAGCGCAGCCGAGCCACCTTGTATGCGCTGAGCCACG CGGTCAACAACTATCATAAGACAAACCCTACAGGGACCCAGGAGCTGCTGGACATTGCTAATTACCTGAT GGAACAGATTCAAGATGACTGCACTGGGGATGAAGATTACACCTATTTGATTCTGCGGGTCATTGGAAAT ATGGGCCAAACCATGGAGCAGTTAACTCCAGAACTCAAGTCTTCAATCCTGAAATGTGTCCAAAGTACAA AGCCATCACTGATGATCCAGAAAGCTGCCATCCAGGCTCTGCGGAAAATGGAGCCTAAAGACAAGGACCA GGAGGTTCTTCTTCAGACTTTCCTTGATGATGCTTCTCCGGGAGATAAGCGACTGGCTGCCTATCTTATG TTGATGAGGAGTCCTTCACAGGCAGATATTAACAAAATTGTCCAAATTCTACCATGGGAACAGAATGAGC AAGTGAAGAACTTTGTGGCTTCCCATATTGCCAATATCTTGAACTCAGAAGAATTGGATATCCAAGATCT GAAAAAGTTAGTGAAAGAAGCTCTGAAAGAATCTCAACTTCCAACTGTCATGGACTTCAGAAAATTCTCT CGGAACTATCAACTCTACAAATCTGTTTCTCTTCCATCACTTGACCCAGCCTCAGCCAAAATAGAAGGGA ATCTTATATTTGATCCAAATAACTACCTTCCTAAAGAAAGCATGCTGAAAACTACCCTCACTGCCTTTGG ATTTGCTTCAGCTGACCTCATCGAGATTGGCTTGGAAGGAAAAGGCTTTGAGCCAACATTGGAAGCTCTT TTTGGGAAGCAAGGATTTTTCCCAGACAGTGTCAACAAAGCTTTGTACTGGGTTAATGGTCAAGTTCCTG ATGGTGTCTCTAAGGTCTTAGTGGACCACTTTGGCTATACCAAAGATGATAAACATGAGCAGGATATGGT AAATGGAATAATGCTCAGTGTTGAGAAGCTGATTAAAGATTTGAAATCCAAAGAAGTCCCGGAAGCCAGA GCCTACCTCCGCATCTTGGGAGAGGAGCTTGGTTTTGCCAGTCTCCATGACCTCCAGCTCCTGGGAAAGC TGCTTCTGATGGGTGCCCGCACTCTGCAGGGGATCCCCCAGATGATTGGAGAGGTCATCAGGAAGGGCTC AAAGAATGACTTTTTTCTTCACTACATCTTCATGGAGAATGCCTTTGAACTCCCCACTGGAGCTGGATTA CAGTTGCAAATATCTTCATCTGGAGTCATTGCTCCCGGAGCCAAGGCTGGAGTAAAACTGGAAGTAGCCA ACATGCAGGCTGAACTGGTGGCAAAACCCTCCGTGTCTGTGGAGTTTGTGACAAATATGGGCATCATCAT TCCGGACTTCGCTAGGAGTGGGGTCCAGATGAACACCAACTTCTTCCACGAGTCGGGTCTGGAGGCTCAT GTTGCCCTAAAAGCTGGGAAGCTGAAGTTTATCATTCCTTCCCCAAAGAGACCAGTCAAGCTGCTCAGTG GAGGCAACACATTACATTTGGTCTCTACCACCAAAACGGAGGTGATCCCACCTCTCATTGAGAACAGGCA GTCCTGGTCAGTTTGCAAGCAAGTCTTTCCTGGCCTGAATTACTGCACCTCAGGCGCTTACTCCAACGCC AGCTCCACAGACTCCGCCTCCTACTATCCGCTGACCGGGGACACCAGATTAGAGCTGGAACTGAGGCCTA CAGGAGAGATTGAGCAGTATTCTGTCAGCGCAACCTATGAGCTCCAGAGAGAGGACAGAGCCTTGGTGGA TACCCTGAAGTTTGTAACTCAAGCAGAAGGTGCGAAGCAGACTGAGGCTACCATGACATTCAAATATAAT CGGCAGAGTATGACCTTGTCCAGTGAAGTCCAAATTCCGGATTTTGATGTTGACCTCGGAACAATCCTCA GAGTTAATGATGAATCTACTGAGGGCAAAACGTCTTACAGACTCACCCTGGACATTCAGAACAAGAAAAT TACTGAGGTCGCCCTCATGGGCCACCTAAGTTGTGACACAAAGGAAGAAAGAAAAATCAAGGGTGTTATT TCCATACCCCGTTTGCAAGCAGAAGCCAGAAGTGAGATCCTCGCCCACTGGTCGCCTGCCAAACTGCTTC TCCAAATGGACTCATCTGCTACAGCTTATGGCTCCACAGTTTCCAAGAGGGTGGCATGGCATTATGATGA AGAGAAGATTGAATTTGAATGGAACACAGGCACCAATGTAGATACCAAAAAAATGACTTCCAATTTCCCT GTGGATCTCTCCGATTATCCTAAGAGCTTGCATATGTATGCTAATAGACTCCTGGATCACAGAGTCCCTC AAACAGACATGACTTTCCGGCACGTGGGTTCCAAATTAATAGTTGCAATGAGCTCATGGCTTCAGAAGGC ATCTGGGAGTCTTCCTTATACCCAGACTTTGCAAGACCACCTCAATAGCCTGAAGGAGTTCAACCTCCAG AACATGGGATTGCCAGACTTCCACATCCCAGAAAACCTCTTCTTAAAAAGCGATGGCCGGGTCAAATATA CCTTGAACAAGAACAGTTTGAAAATTGAGATTCCTTTGCCTTTTGGTGGCAAATCCTCCAGAGATCTAAA GATGTTAGAGACTGTTAGGACACCAGCCCTCCACTTCAAGTCTGTGGGATTCCATCTGCCATCTCGAGAG TTCCAAGTCCCTACTTTTACCATTCCCAAGTTGTATCAACTGCAAGTGCCTCTCCTGGGTGTTCTAGACC TCTCCACGAATGTCTACAGCAACTTGTACAACTGGTCCGCCTCCTACAGTGGTGGCAACACCAGCACAGA CCATTTCAGCCTTCGGGCTCGTTACCACATGAAGGCTGACTCTGTGGTTGACCTGCTTTCCTACAATGTG CAAGGATCTGGAGAAACAACATATGACCACAAGAATACGTTCACACTATCATGTGATGGGTCTCTACGCC ACAAATTTCTAGATTCGAATATCAAATTCAGTCATGTAGAAAAACTTGGAAACAACCCAGTCTCAAAAGG TTTACTAATATTCGATGCATCTAGTTCCTGGGGACCACAGATGTCTGCTTCAGTTCATTTGGACTCCAAA AAGAAACAGCATTTGTTTGTCAAAGAAGTCAAGATTGATGGGCAGTTCAGAGTCTCTTCGTTCTATGCTA AAGGCACATATGGCCTGTCTTGTCAGAGGGATCCTAACACTGGCCGGCTCAATGGAGAGTCCAACCTGAG GTTTAACTCCTCCTACCTCCAAGGCACCAACCAGATAACAGGAAGATATGAAGATGGAACCCTCTCCCTC ACCTCCACCTCTGATCTGCAAAGTGGCATCATTAAAAATACTGCTTCCCTAAAGTATGAGAACTACGAGC TGACTTTAAAATCTGACACCAATGGGAAGTATAAGAACTTTGCCACTTCTAACAAGATGGATATGACCTT CTCTAAGCAAAATGCACTGCTGCGTTCTGAATATCAGGCTGATTACGAGTCATTGAGGTTCTTCAGCCTG CTTTCTGGATCACTAAATTCCCATGGTCTTGAGTTAAATGCTGACATCTTAGGCACTGACAAAATTAATA GTGGTGCTCACAAGGCGACACTAAGGATTGGCCAAGATGGAATATCTACCAGTGCAACGACCAACTTGAA GTGTAGTCTCCTGGTGCTGGAGAATGAGCTGAATGCAGAGCTTGGCCTCTCTGGGGCATCTATGAAATTA ACAACAAATGGCCGCTTCAGGGAACACAATGCAAAATTCAGTCTGGATGGGAAAGCCGCCCTCACAGAGC TATCACTGGGAAGTGCTTATCAGGCCATGATTCTGGGTGTCGACAGCAAAAACATTTTCAACTTCAAGGT CAGTCAAGAAGGACTTAAGCTCTCAAATGACATGATGGGCTCATATGCTGAAATGAAATTTGACCACACA AACAGTCTGAACATTGCAGGCTTATCACTGGACTTCTCTTCAAAACTTGACAACATTTACAGCTCTGACA AGTTTTATAAGCAAACTGTTAATTTACAGCTACAGCCCTATTCTCTGGTAACTACTTTAAACAGTGACCT GAAATACAATGCTCTGGATCTCACCAACAATGGGAAACTACGGCTAGAACCCCTGAAGCTGCATGTGGCT GGTAACCTAAAAGGAGCCTACCAAAATAATGAAATAAAACACATCTATGCCATCTCTTCTGCTGCCTTAT CAGCAAGCTATAAAGCAGACACTGTTGCTAAGGTTCAGGGTGTGGAGTTTAGCCATCGGCTCAACACAGA CATCGCTGGGCTGGCTTCAGCCATTGACATGAGCACAAACTATAATTCAGACTCACTGCATTTCAGCAAT GTCTTCCGTTCTGTAATGGCCCCGTTTACCATGACCATCGATGCACATACAAATGGCAATGGGAAACTCG CTCTCTGGGGAGAACATACTGGGCAGCTGTATAGCAAATTCCTGTTGAAAGCAGAACCTCTGGCATTTAC TTTCTCTCATGATTACAAAGGCTCCACAAGTCATCATCTCGTATGCCGTCTTCTACTGCATATCTGGATA CTTCTCTGGTTCAATTAATAGCTACATTTTTTA Download Select all
Length	6053

CDS Information

Location	129..6038
CDS Sequence	>lcl\|XM_011532809.1_cds_XP_011531111.1_1 [gene=APOB] [protein=apolipoprotein B-100 isoform X1] [protein_id=XP_011531111.1] [location=129..6038] ATGGACCCGCCGAGGCCCGCGCTGCTGGCGCTGCTGGCGCTGCCTGCGCTGCTGCTGCTGCTGCTGGCGG GCGCCAGGGCCGAAGAGGAAATGCTGGAAAATGTCAGCCTGGTCTGTCCAAAAGATGCGACCCGATTCAA GCACCTCCGGAAGTACACATACAACTATGAGGCTGAGAGTTCCAGTGGAGTCCCTGGGACTGCTGATTCA AGAAGTGCCACCAGGATCAACTGCAAGGTTGAGCTGGAGGTTCCCCAGCTCTGCAGCTTCATCCTGAAGA CCAGCCAGTGCACCCTGAAAGAGGTGTATGGCTTCAACCCTGAGGGCAAAGCCTTGCTGAAGAAAACCAA GAACTCTGAGGAGTTTGCTGCAGCCATGTCCAGGTATGAGCTCAAGCTGGCCATTCCAGAAGGGAAGCAG GTTTTCCTTTACCCGGAGAAAGATGAACCTACTTACATCCTGAACATCAAGAGGGGCATCATTTCTGCCC TCCTGGTTCCCCCAGAGACAGAAGAAGCCAAGCAAGTGTTGTTTCTGGATACCGTGTATGGAAACTGCTC CACTCACTTTACCGTCAAGACGAGGAAGGGCAATGTGGCAACAGAAATATCCACTGAAAGAGACCTGGGG CAGTGTGATCGCTTCAAGCCCATCCGCACAGGCATCAGCCCACTTGCTCTCATCAAAGGCATGACCCGCC CCTTGTCAACTCTGATCAGCAGCAGCCAGTCCTGTCAGTACACACTGGACGCTAAGAGGAAGCATGTGGC AGAAGCCATCTGCAAGGAGCAACACCTCTTCCTGCCTTTCTCCTACAAGAATAAGTATGGGATGGTAGCA CAAGTGACACAGACTTTGAAACTTGAAGACACACCAAAGATCAACAGCCGCTTCTTTGGTGAAGGTACTA AGAAGATGGGCCTCGCATTTGAGAGCACCAAATCCACATCACCTCCAAAGCAGGCCGAAGCTGTTTTGAA GACTCTCCAGGAACTGAAAAAACTAACCATCTCTGAGCAAAATATCCAGAGAGCTAATCTCTTCAATAAG CTGGTTACTGAGCTGAGAGGCCTCAGTGATGAAGCAGTCACATCTCTCTTGCCACAGCTGATTGAGGTGT CCAGCCCCATCACTTTACAAGCCTTGGTTCAGTGTGGACAGCCTCAGTGCTCCACTCACATCCTCCAGTG GCTGAAACGTGTGCATGCCAACCCCCTTCTGATAGATGTGGTCACCTACCTGGTGGCCCTGATCCCCGAG CCCTCAGCACAGCAGCTGCGAGAGATCTTCAACATGGCGAGGGATCAGCGCAGCCGAGCCACCTTGTATG CGCTGAGCCACGCGGTCAACAACTATCATAAGACAAACCCTACAGGGACCCAGGAGCTGCTGGACATTGC TAATTACCTGATGGAACAGATTCAAGATGACTGCACTGGGGATGAAGATTACACCTATTTGATTCTGCGG GTCATTGGAAATATGGGCCAAACCATGGAGCAGTTAACTCCAGAACTCAAGTCTTCAATCCTGAAATGTG TCCAAAGTACAAAGCCATCACTGATGATCCAGAAAGCTGCCATCCAGGCTCTGCGGAAAATGGAGCCTAA AGACAAGGACCAGGAGGTTCTTCTTCAGACTTTCCTTGATGATGCTTCTCCGGGAGATAAGCGACTGGCT GCCTATCTTATGTTGATGAGGAGTCCTTCACAGGCAGATATTAACAAAATTGTCCAAATTCTACCATGGG AACAGAATGAGCAAGTGAAGAACTTTGTGGCTTCCCATATTGCCAATATCTTGAACTCAGAAGAATTGGA TATCCAAGATCTGAAAAAGTTAGTGAAAGAAGCTCTGAAAGAATCTCAACTTCCAACTGTCATGGACTTC AGAAAATTCTCTCGGAACTATCAACTCTACAAATCTGTTTCTCTTCCATCACTTGACCCAGCCTCAGCCA AAATAGAAGGGAATCTTATATTTGATCCAAATAACTACCTTCCTAAAGAAAGCATGCTGAAAACTACCCT CACTGCCTTTGGATTTGCTTCAGCTGACCTCATCGAGATTGGCTTGGAAGGAAAAGGCTTTGAGCCAACA TTGGAAGCTCTTTTTGGGAAGCAAGGATTTTTCCCAGACAGTGTCAACAAAGCTTTGTACTGGGTTAATG GTCAAGTTCCTGATGGTGTCTCTAAGGTCTTAGTGGACCACTTTGGCTATACCAAAGATGATAAACATGA GCAGGATATGGTAAATGGAATAATGCTCAGTGTTGAGAAGCTGATTAAAGATTTGAAATCCAAAGAAGTC CCGGAAGCCAGAGCCTACCTCCGCATCTTGGGAGAGGAGCTTGGTTTTGCCAGTCTCCATGACCTCCAGC TCCTGGGAAAGCTGCTTCTGATGGGTGCCCGCACTCTGCAGGGGATCCCCCAGATGATTGGAGAGGTCAT CAGGAAGGGCTCAAAGAATGACTTTTTTCTTCACTACATCTTCATGGAGAATGCCTTTGAACTCCCCACT GGAGCTGGATTACAGTTGCAAATATCTTCATCTGGAGTCATTGCTCCCGGAGCCAAGGCTGGAGTAAAAC TGGAAGTAGCCAACATGCAGGCTGAACTGGTGGCAAAACCCTCCGTGTCTGTGGAGTTTGTGACAAATAT GGGCATCATCATTCCGGACTTCGCTAGGAGTGGGGTCCAGATGAACACCAACTTCTTCCACGAGTCGGGT CTGGAGGCTCATGTTGCCCTAAAAGCTGGGAAGCTGAAGTTTATCATTCCTTCCCCAAAGAGACCAGTCA AGCTGCTCAGTGGAGGCAACACATTACATTTGGTCTCTACCACCAAAACGGAGGTGATCCCACCTCTCAT TGAGAACAGGCAGTCCTGGTCAGTTTGCAAGCAAGTCTTTCCTGGCCTGAATTACTGCACCTCAGGCGCT TACTCCAACGCCAGCTCCACAGACTCCGCCTCCTACTATCCGCTGACCGGGGACACCAGATTAGAGCTGG AACTGAGGCCTACAGGAGAGATTGAGCAGTATTCTGTCAGCGCAACCTATGAGCTCCAGAGAGAGGACAG AGCCTTGGTGGATACCCTGAAGTTTGTAACTCAAGCAGAAGGTGCGAAGCAGACTGAGGCTACCATGACA TTCAAATATAATCGGCAGAGTATGACCTTGTCCAGTGAAGTCCAAATTCCGGATTTTGATGTTGACCTCG GAACAATCCTCAGAGTTAATGATGAATCTACTGAGGGCAAAACGTCTTACAGACTCACCCTGGACATTCA GAACAAGAAAATTACTGAGGTCGCCCTCATGGGCCACCTAAGTTGTGACACAAAGGAAGAAAGAAAAATC AAGGGTGTTATTTCCATACCCCGTTTGCAAGCAGAAGCCAGAAGTGAGATCCTCGCCCACTGGTCGCCTG CCAAACTGCTTCTCCAAATGGACTCATCTGCTACAGCTTATGGCTCCACAGTTTCCAAGAGGGTGGCATG GCATTATGATGAAGAGAAGATTGAATTTGAATGGAACACAGGCACCAATGTAGATACCAAAAAAATGACT TCCAATTTCCCTGTGGATCTCTCCGATTATCCTAAGAGCTTGCATATGTATGCTAATAGACTCCTGGATC ACAGAGTCCCTCAAACAGACATGACTTTCCGGCACGTGGGTTCCAAATTAATAGTTGCAATGAGCTCATG GCTTCAGAAGGCATCTGGGAGTCTTCCTTATACCCAGACTTTGCAAGACCACCTCAATAGCCTGAAGGAG TTCAACCTCCAGAACATGGGATTGCCAGACTTCCACATCCCAGAAAACCTCTTCTTAAAAAGCGATGGCC GGGTCAAATATACCTTGAACAAGAACAGTTTGAAAATTGAGATTCCTTTGCCTTTTGGTGGCAAATCCTC CAGAGATCTAAAGATGTTAGAGACTGTTAGGACACCAGCCCTCCACTTCAAGTCTGTGGGATTCCATCTG CCATCTCGAGAGTTCCAAGTCCCTACTTTTACCATTCCCAAGTTGTATCAACTGCAAGTGCCTCTCCTGG GTGTTCTAGACCTCTCCACGAATGTCTACAGCAACTTGTACAACTGGTCCGCCTCCTACAGTGGTGGCAA CACCAGCACAGACCATTTCAGCCTTCGGGCTCGTTACCACATGAAGGCTGACTCTGTGGTTGACCTGCTT TCCTACAATGTGCAAGGATCTGGAGAAACAACATATGACCACAAGAATACGTTCACACTATCATGTGATG GGTCTCTACGCCACAAATTTCTAGATTCGAATATCAAATTCAGTCATGTAGAAAAACTTGGAAACAACCC AGTCTCAAAAGGTTTACTAATATTCGATGCATCTAGTTCCTGGGGACCACAGATGTCTGCTTCAGTTCAT TTGGACTCCAAAAAGAAACAGCATTTGTTTGTCAAAGAAGTCAAGATTGATGGGCAGTTCAGAGTCTCTT CGTTCTATGCTAAAGGCACATATGGCCTGTCTTGTCAGAGGGATCCTAACACTGGCCGGCTCAATGGAGA GTCCAACCTGAGGTTTAACTCCTCCTACCTCCAAGGCACCAACCAGATAACAGGAAGATATGAAGATGGA ACCCTCTCCCTCACCTCCACCTCTGATCTGCAAAGTGGCATCATTAAAAATACTGCTTCCCTAAAGTATG AGAACTACGAGCTGACTTTAAAATCTGACACCAATGGGAAGTATAAGAACTTTGCCACTTCTAACAAGAT GGATATGACCTTCTCTAAGCAAAATGCACTGCTGCGTTCTGAATATCAGGCTGATTACGAGTCATTGAGG TTCTTCAGCCTGCTTTCTGGATCACTAAATTCCCATGGTCTTGAGTTAAATGCTGACATCTTAGGCACTG ACAAAATTAATAGTGGTGCTCACAAGGCGACACTAAGGATTGGCCAAGATGGAATATCTACCAGTGCAAC GACCAACTTGAAGTGTAGTCTCCTGGTGCTGGAGAATGAGCTGAATGCAGAGCTTGGCCTCTCTGGGGCA TCTATGAAATTAACAACAAATGGCCGCTTCAGGGAACACAATGCAAAATTCAGTCTGGATGGGAAAGCCG CCCTCACAGAGCTATCACTGGGAAGTGCTTATCAGGCCATGATTCTGGGTGTCGACAGCAAAAACATTTT CAACTTCAAGGTCAGTCAAGAAGGACTTAAGCTCTCAAATGACATGATGGGCTCATATGCTGAAATGAAA TTTGACCACACAAACAGTCTGAACATTGCAGGCTTATCACTGGACTTCTCTTCAAAACTTGACAACATTT ACAGCTCTGACAAGTTTTATAAGCAAACTGTTAATTTACAGCTACAGCCCTATTCTCTGGTAACTACTTT AAACAGTGACCTGAAATACAATGCTCTGGATCTCACCAACAATGGGAAACTACGGCTAGAACCCCTGAAG CTGCATGTGGCTGGTAACCTAAAAGGAGCCTACCAAAATAATGAAATAAAACACATCTATGCCATCTCTT CTGCTGCCTTATCAGCAAGCTATAAAGCAGACACTGTTGCTAAGGTTCAGGGTGTGGAGTTTAGCCATCG GCTCAACACAGACATCGCTGGGCTGGCTTCAGCCATTGACATGAGCACAAACTATAATTCAGACTCACTG CATTTCAGCAATGTCTTCCGTTCTGTAATGGCCCCGTTTACCATGACCATCGATGCACATACAAATGGCA ATGGGAAACTCGCTCTCTGGGGAGAACATACTGGGCAGCTGTATAGCAAATTCCTGTTGAAAGCAGAACC TCTGGCATTTACTTTCTCTCATGATTACAAAGGCTCCACAAGTCATCATCTCGTATGCCGTCTTCTACTG CATATCTGGATACTTCTCTGGTTCAATTAA Download Select all
CCDS ID	CCDS1703.1

Protein Information

Protein ID	XP_011531111.1
Protein Name	apolipoprotein B
Molecular Wt. (Da)	219290
Protein Sequence	>lcl\|XM_011532809.1_prot_XP_011531111.1_1 [gene=APOB] [protein=apolipoprotein B-100 isoform X1] [protein_id=XP_011531111.1] [location=129..6038] MDPPRPALLALLALPALLLLLLAGARAEEEMLENVSLVCPKDATRFKHLRKYTYNYEAESSSGVPGTADS RSATRINCKVELEVPQLCSFILKTSQCTLKEVYGFNPEGKALLKKTKNSEEFAAAMSRYELKLAIPEGKQ VFLYPEKDEPTYILNIKRGIISALLVPPETEEAKQVLFLDTVYGNCSTHFTVKTRKGNVATEISTERDLG QCDRFKPIRTGISPLALIKGMTRPLSTLISSSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVA QVTQTLKLEDTPKINSRFFGEGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFNK LVTELRGLSDEAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPE PSAQQLREIFNMARDQRSRATLYALSHAVNNYHKTNPTGTQELLDIANYLMEQIQDDCTGDEDYTYLILR VIGNMGQTMEQLTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDKDQEVLLQTFLDDASPGDKRLA AYLMLMRSPSQADINKIVQILPWEQNEQVKNFVASHIANILNSEELDIQDLKKLVKEALKESQLPTVMDF RKFSRNYQLYKSVSLPSLDPASAKIEGNLIFDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEPT LEALFGKQGFFPDSVNKALYWVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVEKLIKDLKSKEV PEARAYLRILGEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPT GAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQMNTNFFHESG LEAHVALKAGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENRQSWSVCKQVFPGLNYCTSGA YSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATYELQREDRALVDTLKFVTQAEGAKQTEATMT FKYNRQSMTLSSEVQIPDFDVDLGTILRVNDESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERKI KGVISIPRLQAEARSEILAHWSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMT SNFPVDLSDYPKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKE FNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPALHFKSVGFHL PSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNTSTDHFSLRARYHMKADSVVDLL SYNVQGSGETTYDHKNTFTLSCDGSLRHKFLDSNIKFSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVH LDSKKKQHLFVKEVKIDGQFRVSSFYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDG TLSLTSTSDLQSGIIKNTASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLR FFSLLSGSLNSHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLENELNAELGLSGA SMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKVSQEGLKLSNDMMGSYAEMK FDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTVNLQLQPYSLVTTLNSDLKYNALDLTNNGKLRLEPLK LHVAGNLKGAYQNNEIKHIYAISSAALSASYKADTVAKVQGVEFSHRLNTDIAGLASAIDMSTNYNSDSL HFSNVFRSVMAPFTMTIDAHTNGNGKLALWGEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVCRLLL HIWILLWFN Download Select all
Length	1969
Uniprot ID	Q13233
Ensembl Protein ID	ENSP00000382423

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
C	Palmitoylation	1112
N	Glycosylation	1368
N	Glycosylation	1377
N	Glycosylation	1523
N	Glycosylation	185
C	Disulfide Bridge	186;212
C	Disulfide Bridge	245;261
C	Disulfide Bridge	3194;3324
N	Glycosylation	3358
C	Disulfide Bridge	385;390
C	Disulfide Bridge	39;88
C	Disulfide Bridge	478;513
C	Disulfide Bridge	78;97
C	Disulfide Bridge	966;976
N	Glycosylation	983
S	Phosphorylation	520
Y	Phosphorylation	4510
S	Phosphorylation	928
S	Phosphorylation	4507
K	Acetylation	2004
N	Glycosylation	3465
N	Glycosylation	3411
N	Glycosylation	34
N	Glycosylation	3895
T	Phosphorylation	2515
S	Phosphorylation	4048
Y	Phosphorylation	1714
S	Phosphorylation	1723
T	Phosphorylation	2018
S	Phosphorylation	2022
T	Phosphorylation	2707
T	Phosphorylation	3776
S	Phosphorylation	3778

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

No matching records from HPRD source could be found.

Pathway Information

Pathway Name	Pathway ID
Fat digestion and absorption	hsa04975
Vitamin digestion and absorption	hsa04977

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
pfam09172	632-945	DUF1943
cl11721	632-945	DUF1943 superfamily
pfam06448	958-1072	DUF1081
cl05778	958-1072	DUF1081 superfamily
pfam12491	4494-4551	ApoB100_C
cl13872	4494-4551	ApoB100_C superfamily
cd01347	1448-1865	ligand_gated_channel
cl21487	1448-1865	OM_channels superfamily
pfam01347	46-597	Vitellogenin_N
smart00638	46-597	LPD_N
TIGR01612	2060-2490	235kDa-fam
pfam13166	2035-2490	AAA_13
TIGR02169	2132-2487	SMC_prok_A
COG0419	2083-2542	SbcC
COG0419	2075-2477	SbcC
pfam06160	2169-2478	EzrA
COG1196	2092-2458	Smc
TIGR01612	2037-2593	235kDa-fam
COG1340	4258-4523	COG1340
pfam04286	2262-2552	DUF445
PRK04778	2169-2478	PRK04778
COG0610	2161-2430	COG0610
TIGR02168	2259-2520	SMC_prok_B
COG1196	2261-2552	Smc

Ontology Information

HPRD ID	3904
Molecular Class	Transport/cargo protein
Molecular Function	Protein serine/threonine kinase activity (GO:0004674)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO