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General Information
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26317553 | 2015 | Cell line : SW480, SW620, LoVo, Colo205, HCT116 and Caco-2 Source : ATCC, Fudan University Shanghai Cancer Center (Shanghai, China). Sample Type : CRC tumor and normal tissue No. of Sample : 64 CRC, 36 recurrence and 28 without recurrence Stage : TNM Stage II,III | Real-time quantitative PCR and immunohistochemistry,gene transfection, CCK-8 assay, flow cytometry, and invasion assay | Down-regulation | - | Up-regulation of ANO9, as a metastasis-related gene, could be a novel approach for inhibiting CRC progression. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Ion channels / Chloride channels : Calcium activated : Anoctamins |
| Description | - |
| Chromosome | 11 |
| Location | 11p15.5 |
| Start | 417930 |
| End | 442011 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 24082 |
| OMIM ID | - |
| HGNC ID | HGNC:20679 |
| Unigene ID | Hs.501622 |
| Ensembl ID | ENSG00000185101 |
| PharmGKB ID | PA164715791 |
Protein Information
| Protein ID | NP_001012302.2 |
|---|---|
| Protein Name | anoctamin 9 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 782 |
| Uniprot ID | Q9Y2Q3 |
| Ensembl Protein ID | ENSP00000351181 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam04547 | 179-740 | Anoctamin |
| cl21726 | 179-740 | Anoctamin superfamily |
Ontology Information
| HPRD ID | 13613 |
|---|---|
| Molecular Class | Integral membrane protein |
| Molecular Function | Glutathione transferase activity (GO:0004364) |
| Biological Process | Metabolism (GO:0008152) |
Drug Information
No matching records could be found.